LOCUS       DAVAZT010000001        74105 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVAZT010000001 DAVAZT010000000
VERSION     DAVAZT010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 74105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 74105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..74105
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.001"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(803..2053)
                     /gene="ilvA"
                     /locus_tag="VQT45_000001"
     CDS             complement(803..2053)
                     /gene="ilvA"
                     /locus_tag="VQT45_000001"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HET2358414.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(2103..2459)
                     /locus_tag="VQT45_000002"
     CDS             complement(2103..2459)
                     /locus_tag="VQT45_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET2358415.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(2697..2933)
                     /locus_tag="VQT45_000003"
     CDS             complement(2697..2933)
                     /locus_tag="VQT45_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2358416.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(3040..4062)
                     /gene="ilvC"
                     /locus_tag="VQT45_000004"
     CDS             complement(3040..4062)
                     /gene="ilvC"
                     /locus_tag="VQT45_000004"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET2358417.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVVEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(4128..4604)
                     /gene="ilvN"
                     /locus_tag="VQT45_000005"
     CDS             complement(4128..4604)
                     /gene="ilvN"
                     /locus_tag="VQT45_000005"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HET2358418.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(4597..6297)
                     /locus_tag="VQT45_000006"
     CDS             complement(4597..6297)
                     /locus_tag="VQT45_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HET2358419.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(6498..8165)
                     /locus_tag="VQT45_000007"
     CDS             complement(6498..8165)
                     /locus_tag="VQT45_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HET2358420.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(8168..8533)
                     /locus_tag="VQT45_000008"
     CDS             complement(8168..8533)
                     /locus_tag="VQT45_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET2358421.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(8690..8878)
                     /locus_tag="VQT45_000009"
     CDS             complement(8690..8878)
                     /locus_tag="VQT45_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HET2358422.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(8994..9170)
                     /locus_tag="VQT45_000010"
     CDS             complement(8994..9170)
                     /locus_tag="VQT45_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HET2358423.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     DGMWRAENVTQDLI"
     gene            complement(9281..9430)
                     /locus_tag="VQT45_000011"
     CDS             complement(9281..9430)
                     /locus_tag="VQT45_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HET2358424.1"
                     /translation="MDKVETTIKSLCVHHYNLKFYVFNDDLPREWFQLMEKRLETLNS
                     EIVNV"
     gene            complement(9742..11286)
                     /locus_tag="VQT45_000012"
     CDS             complement(9742..11286)
                     /locus_tag="VQT45_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HET2358425.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            11499..11801
                     /gene="gatC"
                     /locus_tag="VQT45_000013"
     CDS             11499..11801
                     /gene="gatC"
                     /locus_tag="VQT45_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HET2358426.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            11801..13267
                     /gene="gatA"
                     /locus_tag="VQT45_000014"
     CDS             11801..13267
                     /gene="gatA"
                     /locus_tag="VQT45_000014"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HET2358427.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDANNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDTKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            13267..14709
                     /gene="gatB"
                     /locus_tag="VQT45_000015"
     CDS             13267..14709
                     /gene="gatB"
                     /locus_tag="VQT45_000015"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HET2358428.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDLHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            14838..15398
                     /gene="efp"
                     /locus_tag="VQT45_000016"
     CDS             14838..15398
                     /gene="efp"
                     /locus_tag="VQT45_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HET2358429.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            15420..15809
                     /locus_tag="VQT45_000017"
     CDS             15420..15809
                     /locus_tag="VQT45_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET2358430.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGVYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            15802..16224
                     /gene="nusB"
                     /locus_tag="VQT45_000018"
     CDS             15802..16224
                     /gene="nusB"
                     /locus_tag="VQT45_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HET2358431.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTNVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKVGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(16273..16650)
                     /locus_tag="VQT45_000019"
     CDS             complement(16273..16650)
                     /locus_tag="VQT45_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2358432.1"
                     /translation="MVLSNGQPTFLSTILSFVLLVIIGPVFEETLDRGYFMNTFFPKS
                     KYYLDVILSGLIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDNLRLTILCHSFF
                     NFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(16991..17176)
                     /gene="briC"
                     /locus_tag="VQT45_000020"
     CDS             complement(16991..17176)
                     /gene="briC"
                     /locus_tag="VQT45_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HET2358433.1"
                     /translation="MTGTETFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRTG"
     gene            complement(17335..18102)
                     /locus_tag="VQT45_000021"
     CDS             complement(17335..18102)
                     /locus_tag="VQT45_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HET2358434.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(18099..18965)
                     /locus_tag="VQT45_000022"
     CDS             complement(18099..18965)
                     /locus_tag="VQT45_000022"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HET2358435.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(19002..20369)
                     /gene="accC"
                     /locus_tag="VQT45_000023"
     CDS             complement(19002..20369)
                     /gene="accC"
                     /locus_tag="VQT45_000023"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HET2358436.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(20381..20803)
                     /gene="fabZ"
                     /locus_tag="VQT45_000024"
     CDS             complement(20381..20803)
                     /gene="fabZ"
                     /locus_tag="VQT45_000024"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HET2358437.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            complement(20800..21285)
                     /locus_tag="VQT45_000025"
     CDS             complement(20800..21285)
                     /locus_tag="VQT45_000025"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HET2358438.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVASEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(21288..22523)
                     /gene="fabF"
                     /locus_tag="VQT45_000026"
     CDS             complement(21288..22523)
                     /gene="fabF"
                     /locus_tag="VQT45_000026"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HET2358439.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(22545..23276)
                     /gene="fabG"
                     /locus_tag="VQT45_000027"
     CDS             complement(22545..23276)
                     /gene="fabG"
                     /locus_tag="VQT45_000027"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HET2358440.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(23310..24230)
                     /gene="fabD"
                     /locus_tag="VQT45_000028"
     CDS             complement(23310..24230)
                     /gene="fabD"
                     /locus_tag="VQT45_000028"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HET2358441.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(24223..25197)
                     /gene="fabK"
                     /locus_tag="VQT45_000029"
     CDS             complement(24223..25197)
                     /gene="fabK"
                     /locus_tag="VQT45_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HET2358442.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVE
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(25316..25540)
                     /locus_tag="VQT45_000030"
     CDS             complement(25316..25540)
                     /locus_tag="VQT45_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET2358443.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(25600..26574)
                     /locus_tag="VQT45_000031"
     CDS             complement(25600..26574)
                     /locus_tag="VQT45_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HET2358444.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANNRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(26574..27008)
                     /locus_tag="VQT45_000032"
     CDS             complement(26574..27008)
                     /locus_tag="VQT45_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET2358445.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(27102..27887)
                     /locus_tag="VQT45_000033"
     CDS             complement(27102..27887)
                     /locus_tag="VQT45_000033"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HET2358446.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            28212..29576
                     /locus_tag="VQT45_000034"
     CDS             28212..29576
                     /locus_tag="VQT45_000034"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HET2358447.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            29579..29950
                     /locus_tag="VQT45_000035"
     CDS             29579..29950
                     /locus_tag="VQT45_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HET2358448.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            30164..31438
                     /gene="serS"
                     /locus_tag="VQT45_000036"
     CDS             30164..31438
                     /gene="serS"
                     /locus_tag="VQT45_000036"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HET2358449.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGTDEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(31463..32362)
                     /locus_tag="VQT45_000037"
     CDS             complement(31463..32362)
                     /locus_tag="VQT45_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HET2358450.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACSGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPALSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(32472..33020)
                     /locus_tag="VQT45_000038"
     CDS             complement(32472..33020)
                     /locus_tag="VQT45_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HET2358451.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(33238..34560)
                     /locus_tag="VQT45_000039"
     CDS             complement(33238..34560)
                     /locus_tag="VQT45_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HET2358452.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGARFIWLYRVFFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(34651..34739)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(34903..37239)
                     /locus_tag="VQT45_000040"
     CDS             complement(34903..37239)
                     /locus_tag="VQT45_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HET2358453.1"
                     /translation="MNKKILETLEFDKVKALFDPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVHFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(37343..37891)
                     /locus_tag="VQT45_000041"
     CDS             complement(37343..37891)
                     /locus_tag="VQT45_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HET2358454.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIFYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(37888..38190)
                     /gene="zapA"
                     /locus_tag="VQT45_000042"
     CDS             complement(37888..38190)
                     /gene="zapA"
                     /locus_tag="VQT45_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HET2358455.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            38277..39158
                     /locus_tag="VQT45_000043"
     CDS             38277..39158
                     /locus_tag="VQT45_000043"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HET2358456.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQLVEENRGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TSDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLSVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            39162..39776
                     /gene="lepB"
                     /locus_tag="VQT45_000044"
     CDS             39162..39776
                     /gene="lepB"
                     /locus_tag="VQT45_000044"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HET2358457.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            40055..42421
                     /locus_tag="VQT45_000045"
     CDS             40055..42421
                     /locus_tag="VQT45_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HET2358458.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLSKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLETIQKHITTIEEELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTHLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(42469..43752)
                     /locus_tag="VQT45_000046"
     CDS             complement(42469..43752)
                     /locus_tag="VQT45_000046"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HET2358459.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     EDGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(43946..44305)
                     /locus_tag="VQT45_000047"
     CDS             complement(43946..44305)
                     /locus_tag="VQT45_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET2358460.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNRFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPITAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNIT"
     gene            complement(44604..45233)
                     /locus_tag="VQT45_000048"
     CDS             complement(44604..45233)
                     /locus_tag="VQT45_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET2358461.1"
                     /translation="MVLSKYYGVADGMNVEGRGSANFIKDNVLITAAHNYYRHDYGKE
                     ADDIYVLPTVSPSQEPFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLG
                     TLGLPTSQKNLTGITVTITGYPSYNFKVHQMYTDKKQVLSDDGMFLDYQVDTLEGSSG
                     STVYDASHRVVGVHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGW"
     gene            complement(45278..45517)
                     /locus_tag="VQT45_000049"
     CDS             complement(45278..45517)
                     /locus_tag="VQT45_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2358462.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(45667..45933)
                     /locus_tag="VQT45_000050"
                     /pseudo
     CDS             complement(45667..45933)
                     /locus_tag="VQT45_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(45958..46266)
                     /locus_tag="VQT45_000051"
     CDS             complement(45958..46266)
                     /locus_tag="VQT45_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET2358463.1"
                     /translation="MDWDFADTCWEKEPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHPELEEIILILFENLFKPRQLYLQPQNSVLRLQIAS
                     "
     gene            complement(46191..46433)
                     /locus_tag="VQT45_000052"
     CDS             complement(46191..46433)
                     /locus_tag="VQT45_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET2358464.1"
                     /translation="MSLADLLEELEAAKDSKKARPMEAYMRHQFSFLGIAVPERNKLY
                     KNIYQKRKKQRLSIGILQTLAGKRSLENTNMWLLTI"
     gene            complement(46434..47066)
                     /locus_tag="VQT45_000053"
     CDS             complement(46434..47066)
                     /locus_tag="VQT45_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2358465.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(47080..48075)
                     /locus_tag="VQT45_000054"
     CDS             complement(47080..48075)
                     /locus_tag="VQT45_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2358466.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLYDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDPDLDASFKS
                     LSGKLNLLTEALQKAENHSLDQEEEIIEKERKRIARDLHDTVSQELFAAHIILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFRLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(48072..48770)
                     /locus_tag="VQT45_000055"
     CDS             complement(48072..48770)
                     /locus_tag="VQT45_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HET2358467.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(48848..49858)
                     /locus_tag="VQT45_000056"
     CDS             complement(48848..49858)
                     /locus_tag="VQT45_000056"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HET2358468.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(49842..50849)
                     /locus_tag="VQT45_000057"
     CDS             complement(49842..50849)
                     /locus_tag="VQT45_000057"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HET2358469.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLTPNPDYSLIQETIALMGDFLAVRGQNLRSFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKSEKIIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(50836..51789)
                     /gene="mvaD"
                     /locus_tag="VQT45_000058"
     CDS             complement(50836..51789)
                     /gene="mvaD"
                     /locus_tag="VQT45_000058"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HET2358470.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVIADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YSVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(51771..52649)
                     /gene="mvk"
                     /locus_tag="VQT45_000059"
     CDS             complement(51771..52649)
                     /gene="mvk"
                     /locus_tag="VQT45_000059"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HET2358471.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(52771..53100)
                     /locus_tag="VQT45_000060"
     CDS             complement(52771..53100)
                     /locus_tag="VQT45_000060"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2358472.1"
                     /translation="MTRKAYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMIPHDFPLYLTVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVN
                     YNGEWVQ"
     gene            53762..54098
                     /locus_tag="VQT45_000061"
                     /pseudo
     CDS             53762..54098
                     /locus_tag="VQT45_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic-modifying protein"
     gene            53998..54585
                     /locus_tag="VQT45_000062"
     CDS             53998..54585
                     /locus_tag="VQT45_000062"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2358473.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCEIAY
                     ALFAYSKVLEPSMFYNDLHTFHAELKKLLEKVTSNTENLGNLQLSWCEGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKIQQVILA
                     CSERDDHGLLMFQGDSGKADLFDFGIGSRGYIGVY"
     gene            54628..55860
                     /locus_tag="VQT45_000063"
     CDS             54628..55860
                     /locus_tag="VQT45_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2358474.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALCIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVHIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLFALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFVTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(55978..56934)
                     /gene="cbpC"
                     /locus_tag="VQT45_000064"
     CDS             complement(55978..56934)
                     /gene="cbpC"
                     /locus_tag="VQT45_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HET2358475.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDDLFDNRPVFEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLRSSGAMA
                     TGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSSGAMATGWYQDGSTWYYLNAGN
                     GDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYNGEWVR"
     gene            complement(57032..57721)
                     /locus_tag="VQT45_000065"
     CDS             complement(57032..57721)
                     /locus_tag="VQT45_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2358476.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            complement(57733..59157)
                     /gene="gndA"
                     /locus_tag="VQT45_000066"
     CDS             complement(57733..59157)
                     /gene="gndA"
                     /locus_tag="VQT45_000066"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HET2358477.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVSDVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEDQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            complement(59233..60627)
                     /gene="mapZ"
                     /locus_tag="VQT45_000067"
     CDS             complement(59233..60627)
                     /gene="mapZ"
                     /locus_tag="VQT45_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HET2358478.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTNSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLVTQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            complement(60640..61797)
                     /locus_tag="VQT45_000068"
     CDS             complement(60640..61797)
                     /locus_tag="VQT45_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HET2358479.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARLPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVERKLELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            complement(61882..62262)
                     /gene="rnpB"
                     /locus_tag="VQT45_000069"
     ncRNA           complement(61882..62262)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VQT45_000069"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(62283..62612)
                     /gene="gpsB"
                     /locus_tag="VQT45_000070"
     CDS             complement(62283..62612)
                     /gene="gpsB"
                     /locus_tag="VQT45_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HET2358480.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            complement(62682..63209)
                     /locus_tag="VQT45_000071"
     CDS             complement(62682..63209)
                     /locus_tag="VQT45_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HET2358481.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            63275..63871
                     /gene="recU"
                     /locus_tag="VQT45_000072"
     CDS             63275..63871
                     /gene="recU"
                     /locus_tag="VQT45_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HET2358482.1"
                     /translation="MINYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            63868..66027
                     /locus_tag="VQT45_000073"
     CDS             63868..66027
                     /locus_tag="VQT45_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 1A"
                     /protein_id="HET2358483.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGIYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLTYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(66194..71497)
                     /locus_tag="VQT45_000074"
     CDS             complement(66194..71497)
                     /locus_tag="VQT45_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HET2358484.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATANENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLFSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKTPGNSTWYKGNRVVAPEPGSVNRLSITLKSDGQLNASNNDVNLFDTVTLPGAVN
                     DNLKNEKKILLKAGTYGNDRTVVSVKTDNQEGVKADDTPAQKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVFLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVNDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGQGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLVSDQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
     gene            complement(71798..73780)
                     /locus_tag="VQT45_000075"
     CDS             complement(71798..73780)
                     /locus_tag="VQT45_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2358485.1"
                     /translation="MKSSKLLALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDDQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQGSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
BASE COUNT        21480 a        16874 c        13714 g        22037 t
ORIGIN      
        1 aaacatatat tcaacgaaaa taattagttc agaattttct tacttccttt ttaaatccga
       61 taatatatag gttttgctag cctctacacc ataaatattt gctaataaaa atactgtatt
      121 attaccctct taaggtgcaa aattattcaa gttcttaaaa aatgcttctc tatttccgta
      181 agatagctta tttcttcgat ttaagaactg aagatgatag ttctaacctt tagaaatcca
      241 agccttctct agctcaaaaa ctcctatctt tcttcctcaa taaatcatct gagagatagg
      301 tattccttat atccttcaaa ttcatcactc ctttggatat tgaggtgcta gcctagaagc
      361 agacacccga ttatctaaac catccttaat agagatgaca agacagataa gctcagttaa
      421 ttacttatat atctttttaa tatggtatat ttgtcaacaa aaagaaatca aatcatacct
      481 tatactcaat gaaaatcaaa gagcaaacta ggaagctagc cgcaaattgc tcaaaacact
      541 gttttgaggt ttcagataga gctaacgtgg tttgaagaga ttttcgaaga gtattaaaga
      601 cagtatgact atgcttgtca atagatagga aatcaaaatg aaggatggaa atctgagcca
      661 aacatcataa gtgctataat gaacagaagt aagaattgca cgataagttt tctaaaacca
      721 taggaatcgt cccctttctt catcttcatt atagcacata tacatcagtt gtacaaataa
      781 tatgatattt ttttattagt cctcagacaa gcatattata aagcgtttca ttaccattta
      841 agttaatata agctggatca aaaccttcca ttctacggat caaacctgca taatcatgct
      901 tatctgccaa agcgatccca atcaatactg ggcctgttcc cttgctagct cgtttgatat
      961 actcaaaacg tgtgatatca tcatttggcc ccaggatatc atttacaaac tcacgcaaag
     1021 ctcctggacg ctgtgggaaa ttgaccacaa agtaatgttt gataccatca taaatcaagg
     1081 cacgctcttc catttctggc atacggttga tatcattatt tcctccagaa atgatacaac
     1141 aaatggtttt ccccttaata tattcagcta aaacctctaa agaggcgata ctagccgctc
     1201 cagcaggttc tgcgactatc ccttgcttag agtaaaggtc aatcaaggtt tcagaaatca
     1261 atccctcatc gacacctacc aaagtttgaa tatgttgacg agttgcttca taggtcaact
     1321 gacctacctt ttgcacagca atcccatccg caaatttatc aatttccttg agtttgactg
     1381 gacctccagc ctcaaaggca gctttcatgg aacgcgctcc attcgcctct actccgataa
     1441 cctcaatctc tggacttgtt tccttgatat aggtagaaac cccggcaatg agaccgccac
     1501 caccaacagg aaccaagaca gcatcaaaat caatcgattc ttttcgagct tcttctaaaa
     1561 tctcataagc aactgttcct tgacctgctt gaacatgagc atcatcaaaa ggatcaataa
     1621 aggtacgatt ttcagagact gtaaattctt gagctgcttt ggctgaggca tcaaaggtat
     1681 ctccaactag tttaatagtt acaaaatccc caccaaaaaa gcgaacctga ccaatctttt
     1741 gttgtggcgt agtaataggc ataaagatag tagcaggaat tttcatttca ttacaagtat
     1801 aggctactcc ctgcgcatga tttcccgcag aagcgcagac taccccacgt tcacgttctt
     1861 ccttgctgag ctgggaaatg gcataatagg caccacgaat tttaaaggag cgaacacgct
     1921 gggcattttc ttttttcaaa taaatcttag caccatactt ctccgataaa taatgatcgt
     1981 aatccagtgg agtattcaca accacaccgt tcaagacctt gtgagccttg attatatctt
     2041 ttgaacttaa catataaaac ctctttttct ataaaaaaca gtcactaatg actgtttttt
     2101 agttattcat ctccgaaaac ttcagtaaca ctttcatggt atttatgagc catacgaatc
     2161 gaaaactctt taggaagttc ataacgattt gtggaaatcc aatcatataa ccattctacc
     2221 aaactttctt cactatcatt acgatggaag ataaaatagt ttaaaatttc tttatattct
     2281 acatcattca aatccaacgt gtctacaaat tgactacgag gaacaaaatt agaatctaat
     2341 tttcttagtt gatctgtcaa ttctcccaat tgtaaatcca actgaaaaaa tagtttttgc
     2401 agttgcctat cagtttcatc acatcctgtc ttgatagaaa acaaattggt aatattcata
     2461 tgatttcaac ccctaaataa gtacatctaa tatcccacga atagctgaag ctaaagtttt
     2521 cgcagtccag tcatttaaac ccgattcttt caatccagat gcaataattt gctctatttg
     2581 atataaaccg ccatctatcg tctcatttat tctgcgaaga ggaccttcaa tataggataa
     2641 agcttctccg aatctaacag ctgatttagg tcctaatgat ttaccaacta tatttgttaa
     2701 tgttttttat ttctcaaaat ccatttcgct atataacgag cagatttagt cgcaccagct
     2761 ctctcaaacg gagaatgaat ttcaagacct tcttctctag ctatttgtgc caatttgaag
     2821 aattgttcaa aggtcatatg caacctacca tcttcaaaat tagcatcatc ataaatgtta
     2881 attacagcat tttcatcata cgaccaatct gctttatttt ggtctgctag cactattacc
     2941 gacggtgtaa ttacattata caactagaac caataataac gatgcaattt ttctcataat
     3001 ctttttcata aaatcatctc cagcgctata tatttctaat tagttataga ttttgaatgc
     3061 atcatcgtcg tttttaccaa caaatggcat tgctttacgc aattctgcac caactttttc
     3121 aatttcaagg ttagctgctt gttcacggta agcagtcaat tttggacgtc cagctttata
     3181 gtcatttaca aagtcatttg caaatttacc attttggatg tctgccaaga cagccttcat
     3241 attttcttta acttgttcag tgattacacg tggacctgat acatagtcac cgtattcagc
     3301 agtgtttgaa atagattgac gcattttctt gaatccacct tcgtagatca agtcaacgat
     3361 caatttcatt tcgtgaagaa cttcaaagta agccaattct ggagcgtaac ctgcttctgt
     3421 caagacttcg aaacctgctt cgataagggc agtcaaacca ccacaaagta cagcttgttc
     3481 accaaacaaa tcttcttcag tttcttcttt gtaagttgtt tcaagaagac ctacacgagc
     3541 cgctccaaca cctttacacc agtccatagc aatgttttta gcatttcctg ttgcatcttg
     3601 gtatactgca taaagagctg gaacaccaaa tccttcttcg taagtacgac gtaccaagtg
     3661 tcccggtcct ttaggagcac acatgaagac atctacatcc gcaggaactt tgataaattc
     3721 aaagtggatg ttgaaaccat gggcaaatcc aactgcgttt ccagcttcca agtttggagc
     3781 gatttctgct tcgtacaatt cttgttgaat ttcgtctggc gccaagatca tgataacatc
     3841 agccaactta gtagcttcta ctactgtgta agtatcaaat ccatcttctt ttgctttatc
     3901 aaaagattta cctggacgta caccgataat aacgtcacga cctgaatcac gcaagttttg
     3961 agcatgcgca tgtccttgtg aaccataacc gataacggcg atttttttac cgtcaagtgc
     4021 tgctacttta acatcttttt catattccat ttgaactgtc atagcttttc tctcttttct
     4081 attatttatt gccttttagg ctggtttaat aaatttaagt tggattttta atcgcgggta
     4141 aatccagttg cacccgttcg agcaatattg cgaataccgt atgggcgaat gactcgcaat
     4201 agggcttcgc tcttttctgc atttcccgtc atctgaatgg taatcgagct tggcgctacg
     4261 tctaccactg ttgcacggaa aggttgaata atcgctaaaa tctcagctct cttctcagct
     4321 ggcgctgaca tcttaaccaa aatcacctcg cgctccaaat gaggcttgtc tgtaatatct
     4381 cgaatgcgaa tcacatcaat ctgacgattg agctgtttga tgatttgctc cacttcatca
     4441 tgagaagcaa catcaataat aatagtgata cgcgatacat tcggatcttc tgttgctcca
     4501 acagagatgc tttcaatatt aacctgacga cgagatagga cacctgtaaa gcgattgagg
     4561 actcctgaac gattttgtag ttttgctgtt aacattctac gcatggaact gcacccccaa
     4621 catctcatga ttactcttac cagccggtac cattggtaac acctgttcct tacgagaaat
     4681 atctacctca attagcatag gaacatcctc agtgatgact tcaaggtctt gagccaaggt
     4741 ctcaggattg tcaaacttat agtttttaat accataagcc tgcgccatca attggaaatc
     4801 aggaagggta tcaaagaccg actctgatgt tctgccttca tagaaggatt cctgccactg
     4861 gcgaaccatt ccaagtgaat gattgttcag cataaccacc ttgattggca ccttgtaaat
     4921 attcaaaata gccaactcct ggttggtcat ttggaaacca ccatccccaa caaacaagac
     4981 tacttcctta tctgggttag caattttagc accgattgct gctggaattc caaagcccat
     5041 tgttcccaaa ccacctgaag tcactaactg acgctcattt tggtagggat aatactgagc
     5101 tgtccacatt tggtgttgac caacgtctgt taccacaatg gcatctccat tcgtcaattc
     5161 accaattcgt tcaataactg cttgcggttg aaccacacgc tctttcttgt cataagaacg
     5221 aacacgattc ttgtctttag tgactttctc aatccacttt tcagtattgt tgtgaactgt
     5281 tggttctgct agcaacattt gcaaggcctt cttagcatct ccaactacag gaatgtctgc
     5341 actgataatc ttgccaatct cagctgggtc aatatcaatg tgggcaacct tagcattctt
     5401 agcgaaagtc ttaggattcc ccgtcaaacg gtcatcgaaa cgagaaccaa tactaatcat
     5461 aaagtccgct tccgtcatgg caatatttgc tgcgaatgac ccgtgcatgc ctcccattcc
     5521 aagaaagagt gggtgactcg ttgcaatcgt tccttgtccc aaaagactgg ttaccactgg
     5581 aatttgatag cgttctgcaa attcatttag ttccgtagca gcctcagcat aactaattcc
     5641 accaccagct aacaagactg gctttttagc cttggacaat tgcttcaaga ttttcttgat
     5701 ttgcatatca ttcggctcaa gagtcggctg ataacttggt aaattcactt ctggtgaata
     5761 aatgaagtct gtttctaaag cagatatgtc ttttggtagg tcaattacaa ctggccctgg
     5821 acggcctgta gttgcgatat ggacagcttc cgtaatgata cgcggaatat cagctgtctc
     5881 acgaacttgg taattgtact tagtgattgg catggtaatt cctacgatgt ctgcctcctg
     5941 aaaggcatcc ttcccaatcc ctgctcgcgc cacctgacct gtaaagacca aaaggggaac
     6001 gctatcgctc atagcatccg caatccctgt aatggcattt gttgctcctg gtccactagt
     6061 gacgacggca acacccaact ttccagttga tttggcataa ccttcagctt catgcaaaca
     6121 accttgctca tggcgcccta gaatgtggcg aatgccttta aaattatata tcgcatcata
     6181 aaaaggcaaa accgcaccac caggataacc aaagatggta tcaactccta aatcacgaag
     6241 tgtttccaaa actaggtccg accccgtctt aggagattct aaactgattt tctccattgt
     6301 tcccctttct ttcctcttaa aaataacttg ttactatcat accatttttt caaaattttt
     6361 caagataaaa gaagaaattt tctgaatttt ctattttaac gtttatttat gaatgttatt
     6421 tttgttttta ttaaaaagat accgatttca tttactaaaa aagaaaaaag aactgatttc
     6481 tcagtccttc attaatctta ttccacacta aataggtatg ggtaaacagg ttgttgacct
     6541 tggtgaatct cgacttcaac gtcttcgaat tcttctacga tttcttgagc gatttcattg
     6601 gcaagttctt cgcttccgtc ttcaccgaca tagaaggtta cgatttcact atcttcatcc
     6661 aacatatgtt tcaaggtttc agtcaatgtt tggtgcatat cagggtttga cacaagaatt
     6721 tttccatcca ccatacctag attatcgttt tcatggattt ctaagccatc gatcgttgta
     6781 tcacgcacgg ctgttgtgac gcttccgcta acgacatcgc taagagcagc tgtcatacgc
     6841 tcttggtttt cttcaatgga cttgcttgga tcaaaggcaa gaagacttgt cataccttga
     6901 ggaagagtgc gagcctctac cactactgct ggttgctcca aaacttctgc cgcagattga
     6961 gctgccatga agatgttctt gttgtttggc aagaagatga tgttacgggc attgacctgt
     7021 tcaacagcct tgataaagtc ttctgttgaa gggttcatgg tttgaccgcc ttcgataaca
     7081 taatccacgc cttgagaaca gaagatatct gctagacctt taccagccac cacagcaatc
     7141 aaagcatact ctttttcttc agccgacttg ataacttgag tagcttcttt ctcaacctgt
     7201 gcttcgtgtt ggttacgcat attgtcaact tttaccttga ccaagctacc atatttgaga
     7261 ccttcttgca taacaagtcc tggatcttct gtatgaacat ggactttgac aatttcatca
     7321 tcgttaacaa cgaggagaga atccccaagc tcatccaagt agttacggaa ttcatcgtag
     7381 tcaaaatctt tagcataggt tggaccttgc ttaagagcta ccatgatttc agtacagtaa
     7441 ccaaacgtga tgtcctcagt cgctacgtga ccagctacag acttatgatg ctctacattg
     7501 atcatctcac tcatgttggc aggagtcgct acaaagtcct cagatgcaat atattcgcca
     7561 gtaagggctg aaaggaaacc ttcgtagatg aagaccaatc cttgaccacc tgagtccaca
     7621 acgccaactt ctttcaatac tggaagcatg tctggtgttt tagctagagc tgttttagca
     7681 ccttccaagg ctgcgcgcat gacttcaaca gtgtcatctg tttgctcagc ttttttctta
     7741 gcaccgatag cagctccacg agaaactgtc aaaatcgttc cttcaacagg tttcatcact
     7801 gccttatagg caacttccac acctgattgg aaggccagag ccaagtcttg acctgttaac
     7861 tcgtctttat ccttgatagc ttgggaaaat ccacggaaaa gctgagacgt aatcactcct
     7921 gagttcccac gcgcacccat caaaagccct ttggcaagaa tgctcgctac ttctccaact
     7981 gtagaagctg gcttgtctgc aacttcttta gcaccatttt caatggtcat tcccatattt
     8041 gtcccagtat ctccatctgg aactggaaag acgtttaatg aattgacata ttcagcttgc
     8101 ttattcaagc gagttgatgc agcctgcacc atttcttgaa ataagctagt agtaattttt
     8161 gacacggtta ttctcctaca actttgatat tttgaatgta gacatttaca gtctgagcag
     8221 taattccaag ctggttttcc aagctaaagg caacacgctc ttgaatgttt tttgacactt
     8281 cactaatctt tgttccgtag cttaacacgg tatatacatc aactgcaata ctgccatctt
     8341 cggctgcctt tacgacgaca cctttagaat aattttcctt acctagcagg gcttggaaat
     8401 tatctttgag ggcattttta ctagccatac cgaccacacc aaaaatctca gttgctgctc
     8461 cacctacgac ggttgcaatc acttcatctg ttagttcgat ttgaccatct tttgtattaa
     8521 tttttacagt catccttttt acctcaacta gttgatactc tattttatca tatttcagcc
     8581 caagtgtaaa agcagaatga tgtatcagcg gatatttact ctatttttca aacgatgtta
     8641 tacccacaat aaaagaaaaa agaccctaag gtctcctttg cttttattat taaacgcgtt
     8701 caactttacc tgatttcaaa gcacgagctg aagcccaaac ttttttaggt ttaccatcga
     8761 taagaacagt aactttttga aggtttggtt ttacggcacg ttttgtttgg ttcatcgcgt
     8821 gtgaacggtt gtttcctgat acagtcttac gacctgtaaa gtaacatact ttagccattg
     8881 tgttttcctc ctattagatc taatatagcg gatgtgctag caccacatac cgtactatgt
     8941 tatcacactt tcttgttttt tgcaagggaa ttggaagatt ttttatttgt gtcttaaatc
     9001 aggtcttgcg tgacattttc tgctctccac atgccatcgt tgattaacag aacaccagaa
     9061 ttaaaattat gtgtataaaa atcatctcta actgcagcta agggtatagc cgtcaagtcc
     9121 aaatcccaca gctcatctat cgattttctt acaacaatat ctgaatccaa atacagtaca
     9181 cgagactcgc ttacatactt tggaataaaa tacctaaaaa agccgcatat gaaagtccct
     9241 caaaggggag acgataacct ttcagaatat tactgtcaat ctaaacattc acaatctcac
     9301 tattcaaagt ctctagtctt ttttccatca attggaacca ttctcgcgga aggtcatcat
     9361 taaaaacata aaacttaaga ttataatgat gaacacaaag agattttatt gttgtttcaa
     9421 ctttatccat ataagcatta tctgcaccta agacaatcgc ttttttctct tttttctctt
     9481 ctttcacttt ttatctcatt tctttttatt cccatcatat gtttctacgt aaccattatt
     9541 ttcgcctatt cgttcgtaaa accataccag tggagatttt agatgaagtc ccattacggt
     9601 ttacaatttt tacattacga cacggagttt tacaaatcga tttcatttgc caaacgtagt
     9661 tagtgaggca gttagctagt tcgccaaata gcgactagcg tccaacaatt tggaacttta
     9721 gttccaattg ttggtactga gtcacatctt ctcctctaac tctacgtctg gatacttgtc
     9781 agcaaaccag cggagggcaa agtcattttc aaagagaaag actggttggt caaaacggtc
     9841 tttggctaag atattgcgac ttgacgacat ccgttcatcc aagtcctcag gcttgatcca
     9901 acgaacggtc tttttaccca ttgggttcat aactacttct gcattgtact cgccttccat
     9961 gcggtgttta aagacttcaa actggagttg acctacagcg cctagcatgt actcacctgt
    10021 ttggtaattc ttataaagct gaacggctcc ttcttgcacc aattgctcaa tccccttgtg
    10081 gaaggatttt tgcttcataa cattcttagc agaaactttc atgaaaattt caggagtaaa
    10141 ggttggcagt ggttcaaatt caaacttgtt tttaccaact gtcaaggtat ccccaacttg
    10201 ataagtaccg gtatcgtaaa ccccgataat atcacctgcc acggcattga tcacattctc
    10261 acgactttcc gccataaact gggtaacatt agatagtttg gcccccttac cagtacgagg
    10321 gagattgaca ctcatgccac gctcaaattc gcctgatacg atacggacaa aggcaatacg
    10381 gtcacggtga cgaggatcca tgttggcttg gattttaaag acaaagcctg agaaatcctt
    10441 gtcataagga tccacaattt caccgtctgt tttcttgtga ccatgtggtt ctggagcaaa
    10501 cttgaggaag atttcaagga aggtctgcac accaaagttt gtcagggctg aaccgaaaaa
    10561 gacaggcgtc aattctccag ccagaatagc ttcctctgaa aactcattcc cagcttcatt
    10621 taaaagctca atgtcatcct tgacttgctc gtagaaagga ttgctaccaa agagtttgtc
    10681 cccgtcttct agactggcaa aacgctcatc ccctttgtaa agctctaaac gttggttata
    10741 gaggtcatac aagccctcaa aggctttccc catcccgata ggccagttca tagggtagct
    10801 agcaatgccc aagatttctt ccaattcttg caagagatcc aaaggctcac gaccgtcacg
    10861 gtccagcttg ttcataaagg taaaaactgg aatgccacga tgtttcacaa cctcaaacaa
    10921 tttcttggtt tgagcctcga tccccttggc agagtccacg accatgaccg cagcatccac
    10981 cgccatcaag gtacgatagg tatcttctga gaagtcctcg tgccctggcg tgtctaagat
    11041 attcacgcgc ttgccgtcgt agtcaaattg cataacagat gaagtaacag aaatcccacg
    11101 ttgcttctcg atatccatcc agtcagattt agcaaaagtc cctgttttct tcccttttac
    11161 cgtaccagcc tcacgaatct cacccccaaa gtagagtaac tgctcagtga tggttgtttt
    11221 ccccgcgtcc gggtgggaga taatggcaaa ggtacgacgt ttcttaattt cttcttgaat
    11281 attcataagt tctctttctt tgattctcta tttttcttgt ttcaatagct gagaatgatt
    11341 tttacattgg attttaccat tcctttcaac attccattat atcggatttt agcatttttt
    11401 tcaatttcta tttcttttca cttccccctc ccttatttat aggaaaatat ggtaaaatag
    11461 aacagactaa aaatcatcat ttcacgaaag gatgcaagat gaaaattacg caagaagagg
    11521 taacacacgt tgccaatctt tcaaaattaa gattctctga agaagaaact gctgcctttg
    11581 cgaccacctt gtctaagatt gttgacatgg ttgaattgct gggcgaagtt gacacaactg
    11641 gtgtcgcacc tactacgact atggctgacc gcaagactgt actccgccct gatgtggccg
    11701 aagaaggaac agaccgtgat cgcttgttta aaaacgtacc tgaacaagac aactactata
    11761 tcaaggtgcc agctatccta gacgatggag gagatgccta atgactttta acaataaaac
    11821 tattgaagag ttgcacaatc tccttgtctc taaggaaatt tctgcaacag aattgaccca
    11881 agcaacactt gaaaatatca agtctcgtga ggaagccctc aattcatttg tcaccatcgc
    11941 tgaggagcaa gctcttgttc aagctaaagc cattgatgaa gctggaattg atgctaacaa
    12001 tgtcctttca ggaattccac ttgctgttaa ggataacatc tctacagacg gtattctcac
    12061 aactgctgcc tcaaaaatgc tctacaacta tgagccaatc tttgatgcga cagctgttgc
    12121 caatgcaaaa accaaaggca tgattgtcgt tggaaagacc aacatggacg aatttgctat
    12181 gggtggttcc ggtgaaactt cacactacgg agcaactaaa aacgcttggg accacagcaa
    12241 ggttcctggt gggtcatcaa gtggttctgc cgcagctgta gcctcaggac aagttcgctt
    12301 gtcacttggt tctgatactg gtggttccat ccgccaacct gctgccttca acggaatcgt
    12361 tggtctcaaa ccaacctacg gaacagtttc acgtttcggt ctcattgcct ttggtagctc
    12421 attagaccag attggacctt ttgctcctac tgttaaggaa aatgccctct tgctcaacgc
    12481 tattgccagc gaagatacta aagactctac ttctgctcct gtccgcatcg ccgactttac
    12541 ttcaaaaatc ggccaagaca ttaagggcat gaaaattgct ttgcctaagg aatacctagg
    12601 cgaaggaatt gatccagagg ttaaggaaac aatcttaaac gcggccaaac actttgaaaa
    12661 attgggtgct atcgtcgaag aagtcagcct tcctcactct aaatacggtg ttgccgttta
    12721 ttacatcatc gcttcatcag aagcttcatc aaacttgcaa cgttttgacg gtatccgtta
    12781 cggctaccgc gcagaagatg cgactaatct tgatgaaatc tatgtaaaca gccgtagcca
    12841 aggttttggt gaagaagtga agcgccgtat catgctgggt actttcagtc tttcatcagg
    12901 ttactacgat gcctactaca agaaggctgg acaggtccgt acacttatca ttcaagattt
    12961 cgaaaaagtc ttcgcggatt acgatttgat tttgggtcca actgctccaa gtgttgccta
    13021 tgacttggat tctctcaacc atgacccagt tgccatgtac ttagccgacc tcttgaccat
    13081 acctgtaaac ttggcaggac tgcctggaat ttcgattcct gctggattct ctcaaggtct
    13141 acctgtcgga ctccaattga ttggtcccaa gtactctgag gaaaccattt accaagctgc
    13201 tgctgctttt gaagcaacaa cagactacca caaacaacaa cccgtgattt ttggaggtga
    13261 caactaatga actttgaaac agtcatcgga cttgaagtcc acgtagagct caacaccaat
    13321 tcaaaaatct tctcacctac ttctgcccac tttggaaatg accaaaatgc caacactaac
    13381 gtgattgact ggtctttccc aggagttcta ccagttctca ataaaggggt tgttgatgcc
    13441 ggtatcaagg ctgctcttgc cctcaacatg gacctccaca aaaaaatgca ctttgaccgc
    13501 aagaactact tctaccctga taatcccaaa gcctaccaaa tttctcagtt tgatgagcca
    13561 atcggttata acggctggat tgaagtcgag ctagaagacg gtacgaccaa gaaaattggt
    13621 atcgaacgcg cccacttaga ggaagacgct ggtaaaaaca cccacggtac agacggctac
    13681 tcttacgttg accttaaccg ccaaggggta cctttgattg agattgtatc tgaagccgat
    13741 atgcgttcgc cagaggaggc ctatgcttat ctgacagccc tcaaggaagt tatccagtac
    13801 gctggcattt ctgacgttaa gatggaagaa ggttctatgc gtgtggatgc caacatctcc
    13861 cttcgtcctt atggtcaaga gaaattcggt accaagactg aattgaagaa cctcaactcc
    13921 ttctcaaacg ttcgtaaagg tcttgaatac gaagtccaac gccaggctga aattcttcgc
    13981 tcaggtggtc aaatccgcca agaaacacgc cgttacgatg aagcgaataa agcaaccatc
    14041 ctcatgcgtg tcaaggaagg ggctgctgac taccgctact tcccagaacc agacctaccc
    14101 ctctttgaaa tttctgacga gtggattgag gaaatgcgga ctgagttgcc agagtttcca
    14161 aaagaacgtc gtgcgcgtta tgtatctgac cttggtttat cagactacga tgctagtcag
    14221 ttgactgcta ataaagtcac ttctgacttc tttgaaaaag ctgttgccct aggtggtgat
    14281 gccaaacaag tctctaactg gctccaaggg gaagtcgctc agttcttgaa tgctgaaggt
    14341 aaaacactgg aacaaatcga attgacacca gaaaacttgg ttgaaatgat tgccatcatc
    14401 gaagacggta ctatttcatc taagattgcc aagaaagtct ttgtccatct agctaaaaat
    14461 ggcggtggcg cgcgtgaata cgtggaaaaa gcaggtatgg ttcaaatttc agatccagct
    14521 atcttgatcc caatcatcca ccaagtcttt gccgataacg aagctgctgt tgccgacttc
    14581 aagtcaggca aacgtaacgc cgacaaagcc tttacaggat tccttatgaa ggcaaccaaa
    14641 ggccaagcca acccacaagt tgcccttaaa ctacttgcac aggaattggc gaagttgaaa
    14701 gaaaactaga cagaacaaaa ccagccctaa ggttggtttt ttcttctcta ccaactccca
    14761 ataactattt tggctttatt tccagagtat tttatggtaa aatgaagagt aataatattt
    14821 attaaagagg taaaaacatg attgaagcaa gtaaattaaa agctggtatg acctttgaaa
    14881 cagctgacgg caaattgatt cgcgttttgg aagctagtca ccacaagcca ggtaaaggaa
    14941 acacgatcat gcgtatgaaa ttgcgtgatg tccgtactgg ttctacattt gacacaagct
    15001 accgtccaga ggaaaaattt gaacaagcta ttatcgagac tgtcccagct caatacttgt
    15061 acaaaatgga tgacacagca tacttcatga atacagaaac ttacgaccag tacgaaatcc
    15121 ctgtagtcaa tgttgaaaac gaattgcttt acatccttga aaactctgat gtgaaaatcc
    15181 aattctacgg aactgaagtg atcggtgtca ccgttcctac tactgttgag ttgacagttg
    15241 ctgaaactca accatctatc aaaggtgcta ctgttacagg ttctggtaaa ccagcaacga
    15301 tggaaactgg acttgtcgta aacgttccag acttcatcga agcaggacaa aaactcgtta
    15361 tcaacactgc agaaggaact tacgtttctc gtgcctaatc tctagaaaga ggtcattcta
    15421 tgggaattga agaacaactt ggcgaaatcg ttatcgcccc acgtgtactt gaaaaaatca
    15481 ttgctatcgc tactgcaaag gtagagggtg ttcactcttt ttcaaacaga tcagtgtctg
    15541 ataccctttc aaaactttca ctcggccgtg gcgtttatct taaaaacgtg gacgaagaac
    15601 tcacagcaga tatctatctc taccttgagt acggagtaaa agttcctaag gtagcggttg
    15661 ctatccagaa agctgtcaaa gatgccgtcc gtaatatggc tgatgtagaa ctcgctgcta
    15721 tcaatattca cgttgcaggt atcgtcccag ataaaacacc aaaaccagaa ttgaaagatc
    15781 tatttgacga ggacttcctc aatgactagt ccactattag aatctagacg ccaactccgt
    15841 aaatgcgctt ttcaagctct catgagcctt gagttcggta cgaatgtcga aactgcttgt
    15901 cgtttcgcct atactcatga tcgtgaagat acggatgtac aacttccagc ctttttgata
    15961 gacctcgttt ctggtgttca agctaaaaag gaagaactag ataagcaaat cactcagcat
    16021 ttaaaagtag gttggaccat tgaacgctta acgctcgtgg agagaaacct ccttcgcttg
    16081 ggagtttttg aaatcacttc atttgacact cctcagctgg ttgctgttaa tgaagctatc
    16141 gagcttgcaa aggacttctc cgatcaaaaa tctgcccgtt ttatcaatgg actgctcagc
    16201 cagtttgtaa cagaagaaca ataaaaagaa aaagtgtttg atagatatca aacacttttt
    16261 ctttgcctcc cactatctaa aaaaatgata atagatataa ttgtaaacaa aaatccagat
    16321 aggttttgca tgattgagaa agttaaaaaa actatggcag agaatcgtta atctcagatt
    16381 gtcggtagaa cgataaacaa gggcaaaaaa gaaaccaatc agactataat ataataaact
    16441 aattggatct ctgtgagata gtatcaaatg gctaatccca aagataaggc ctgataagat
    16501 gacatctaaa tagtactttg acttaggaaa gaaggtattc ataaaatacc ctctatcaag
    16561 agtctcctca aaaacaggac cgatgattac aagcaggaca aaagataaga tagtcgataa
    16621 aaaggttggt tgtccatttg aaagaaccac ggtaaaatac tcatcatgaa tattcctatg
    16681 gttaatcaaa tgagcatagc gtgcctaaaa attaccgaga atctgataaa ccacataagt
    16741 tgcaaataag gagaagacaa atgaccagtc ccagctcttt ttctttttta acctccaaat
    16801 taatagaaaa ggaaacttcc cactaatccc actgttaaaa taagagaata gacatcagct
    16861 cctaacccta aaatgatcgt cacatacaat ccaattgttt gtggtaaata ggtagatagt
    16921 aaaataataa gcaaaaatat tccaaattgt cttagtttct ttgtgtttct catcgtactt
    16981 ttttgaaaga ttaccctgtt cggaagccgt acttccaagc atctatataa gaattaagtg
    17041 ccccttgcct catataggga gcaaattctc tataatataa ccatctacta tatccatctt
    17101 cccaaacagc aagaccacct gaagtttgct ccaagtcctc agttgaaaga actgtaaatg
    17161 tttctgtacc tgtcattgca agtaccttct taaaatagat tgttgtaggc tcacatttat
    17221 agtatatttc tttttttgtc tattttatag tctatctcct caactggcaa tttttcgacc
    17281 tgaattgcat ttttccataa aaaatgagac ctttctagtc tcatttagtc attcttagta
    17341 ttttctaaat cgttgatagc gttcttccag caactcttct agcggttttt gtgaaagtct
    17401 agccagctcc gtttggagtt cttttttgac actcttaatt agttctttac tagaaagtcc
    17461 tacttcagaa atcaccttat ccaccacgtc catttctaac agttcatgcg aagtgatttt
    17521 catcagttct gctgcttcca tggcgcgagt accgtccttc cataaaatgg aagcaaagcc
    17581 ttctggactg agaatggcat agatagaatt ttccagcatc cagacacggt ccgcgacagc
    17641 tagagccaga gccccgcctg aaccaccttc accgataata atggcgataa taggaacttt
    17701 caggtcactc atttccatga gattgcgagc gatagcttcc ccttgaccac gttcttccgc
    17761 tccgacacca ggataagcac ctgctgtatt gataaaggtc acaactggac ggccaaattt
    17821 ctcagcctgt ttcatcaacc gcagtgcctt tcggtagcct tctggatgtg gttggccaaa
    17881 attccgtttg aggttgtctt gcaaactctt gcctttttgg ataccaacca ctgttacagc
    17941 ttggtctcca agccaaccaa taccaccaac aactgcacca tcatcacgaa aagaacggtc
    18001 accatgtaat tggataaatt catcaaaaat gcctgtcgca aagtccaagg ttgtcaagcg
    18061 actctgctca cgcgcttctc tgactatttt tgcaatattc atctaggact ccctccatgc
    18121 aatctgacta ggctagcaat cgtatctggt aagtctcttc ttttgacaat agcatccaca
    18181 aagccatgtt ctaataggaa ttctgccttt tggaaatcct caggcaagct ttcacgaacc
    18241 gtattttcaa tcacacgacg cccagcaaaa ccaaccaagc tctgtggttc agccagaatg
    18301 atatcgcctt ccatagcgaa agaagctgtc acaccaccag tcgttggatc tgtcaaaatg
    18361 gtcaggtaaa agagaccagc atttgaatgg cgtttaaccg ctgcagagat cttagccatc
    18421 tgcatgagac tcatgattcc ttcctgcata cgggctccac cagaggctgt gaataggaca
    18481 actggtaatt tttcgacagt cgcatactca aacaaacgag tgattttttc acctacaacc
    18541 gtacccatag aagccatgat aaaattagaa tccataatcc caagagccac agtctgacct
    18601 ttaataagag cagttcctgt cacaacggct tcatgcagac ctgttttttc acgcatagat
    18661 gccagtttct tttggtaacc agggaaatgc aagggatcct tgctttcaat ccctgtaaac
    18721 aattctttga aggttcccat atcaatcgtc aaagccaagc gttcttgggc agaaatacga
    18781 aaggtatagc tacagtgcgg acagatacgt tcacttccca gatccttctg atagatggta
    18841 tgcttacagc ctggacactg ggaaaataat tcatctggaa cctctggctt agcttgaggt
    18901 ttttccctaa ccgaacgatt gggattgatt cgaatatact tatctttttt actaaataga
    18961 gccattgatt ccccttttcg gtttaaactc ttaaagtcat tttattcttt ttcttgatat
    19021 ttaggtaaga aggtttccat caagaaggaa gtatcataat ccccagcaat gacattgcga
    19081 tctgaaatga gatcaagctg gaaatctgca ttggtctgca ctccttcaat ctctaattca
    19141 tagagggcac gttgcatttt catcaaggcg tcaaaacgat tttcgccgtg tactatgatt
    19201 ttggcaatca tactatcata ataaggcgga atggtataac ctggataaac tgctgaatcc
    19261 acgcgcaagc caactccacc acttggcaga tagagattag taatcttacc tggacttgga
    19321 gcaaagttaa aggctgggtt ttctgcattg atacgacact cgatggcatg accgcgtagg
    19381 acaatatctt cttgcttaac agacaaaggc tgacctgccg caatgcaaat ctgttcctta
    19441 acgatatcaa cacctgaaac aaactctgtt actggatgtt ctacctgaac acgagtattc
    19501 atctccatga aatagaaatt gctacttgct tcatcaagaa gaaattcaat ggttcctgca
    19561 ttctcatagc caacaaactc tgccgctcga acagcagcag cacctatttc atgacgcagc
    19621 gtttttccga ttgcaatcga gggactttct tccaaaacct tttggttatt cctttgaaga
    19681 gaacaatccc gttcacccaa gtgaatcaca tgtccatgct catcacctag gatttgaacc
    19741 tcaatgtgcc gagctggata gataacccgt tctatgtaca tggcaccatt gccataattg
    19801 gccttggcct cactagaggc agtttcaaag gcagaaacga ggtcatctgg tttttcaacc
    19861 ttacgaatcc ctttaccacc tccacctgct gaagccttga gcataacagg atagccaatt
    19921 ttttcagcaa caatcaaagc ttcttcagag ttatgcactt ctccatctga acctggtata
    19981 acaggcacac ctgctttaat catctgagca cgcgcattga tcttatcccc catcatatcc
    20041 ataacatgac cagatggacc gataaacttg atacctactt cttcacacat ggtcgcaaat
    20101 ttggaatttt cactgagaaa tccaaaacca gggtgaatag cttctgcctc agtcaagact
    20161 gcagctgata gaactgcatt aatattgaga taagactctg ttgccttgcc aggaccaata
    20221 caaactgctt catctgccaa cagcgtatga agagcttcct tatcagcagt tgaataaacc
    20281 gctaccgtcg caatccccaa ttcacgtgcc gcacggataa tacgaaccgc aatttcacca
    20341 cgattggcaa ttaaaatttt tcgaaacatg gagaacctcc ttagttccca attgcaaaag
    20401 taagggtacc actggctgca agcttgccat ccacttcagc ctttgcttca accacagcta
    20461 tggtgccacg acgttttaca aaagtcgctg tcataaccaa ttggtcgcct ggtacaactt
    20521 gcttcttgaa cttaacctta tccataccag cgtaaaagac cagttttcct ttattttcag
    20581 gttttgataa ctccaacaca ccagcagttt gcgccaaggc ttccataatc agaacacctg
    20641 gcataactgg gtattgagga aagtggccgt taaagaaagg ctcgttgatg gtcacatttt
    20701 tgatagcaac aatggtatcc tcgctcacct ccaagacacg gtccactaga agcataggat
    20761 aacggtgggg aagggcttct ttgattcctt gaatatcgat catttgatac gtaccaatcc
    20821 tttaccaaac tcaaccattt cttcgttaga gacgagaatt tccgttacca caccatcctt
    20881 aggagctggg atttcattca tgactttcat ggcttcgata attaccaatg tttgaccttt
    20941 tttgacacta tcaccaactg taacgaaggc aggtttatct ggtccagcag ccaagtaaac
    21001 cactccaaca agtggactct ctacaagatt tccctcacta gccacacttg cttcagctgg
    21061 agctggaact tcttctgcta cagtctctgc tggagcagat gtaggagcta ctggactcgg
    21121 tgttgctaga acgggtgctg gagcgacttg agttgcaact tcaggcacag gtctcgcttc
    21181 attcttgcta aactgcaact catccgtccc atttttataa gaaaattctc tcaaacttga
    21241 ctggtcaaat tgagtcatca agtctttaat atcgtttaaa ttcatactta tctattctcc
    21301 caacgtttga aagcaagaac tgcattgtgg cctccaaaac caaaagtatt tgaaatagcg
    21361 tatggaattt ctttctccaa gccttgtcca taaacgacat tagcttcgat ataatctgat
    21421 acttcacttg tcccagctgt cattggtaca aagttatgac gcatagcttc gatggtgacg
    21481 atagcttcta ctgcacccgc agcccccagc aaatgtcctg taaaagactt ggttgatgat
    21541 acaggtactt ccttaccaag aacagctacg atagcaccac tttctccttt ttcattggca
    21601 ggagttgacg ttccgtgagc attgacatag gctacttgct ctggagaaat ctcagcttct
    21661 tccaaggcta gtttgatggc cttgatagct ccctgacctt ctggatgtgg agaagtcatg
    21721 tggtaggcat cacaagtatt tccgtaacca accacttcag ccaggatagt agctccacgt
    21781 ttttcagcgt gttcaagact ttctagaacc aacatccctg aaccttcacc cataacaaac
    21841 ccattgcgat ccttatcaaa tgggatcgaa gcacgagttg gatcctctgt agtagagaga
    21901 gctgttaagg cttggaaacc agcgatggca aaaggtgtga tagaagcttc tgttcctccc
    21961 accaacatca catcttggaa accaaactta atggagcgga aggcatcccc aatcgcatca
    22021 tttgatgaag agcaggcagt attgatagat ttacaaacac cgtttgcacc aaaacgcatg
    22081 gctacattcc cagaagccat atttggtaaa gcttttggaa gagtcattgg tttgacacgt
    22141 ttgggtcctt tttcatgaag gcgaagtacc tgatcttcaa tttccttgat tccaccaata
    22201 ccagatgcaa cgataacacc aaaacgatcc ctattaagag cctctacatc aagattggca
    22261 tgatttacag cctcttgggc tgcatacaag gcatataaag aatagttatc aaaacggttg
    22321 gtatcttttt ttacaaagta tttatcgaac ggaaaatctt ggatttctgc cgcattatgc
    22381 acatcaaagt cactatgatc aaattttgta atgccaccaa tgccgatttt cccagttgct
    22441 aaactattcc aaaattcttc tggtgtattt ccgattggag atgttactcc ataacctgtt
    22501 accactactc gatttagttt cattcttttc acctctagct ttcgctacat acttaagcca
    22561 ccatcaatgg caatcacttg accagttaga taatcttggc ctgctaaaaa tactgtcaaa
    22621 tctgcaacct gctctgcctg cccaaattct ttcatcggaa tctgagctag tgtagcttcc
    22681 ttaatcttat ctgataagat agctgtcata tcagactcaa tcattcctgg agcaatcaca
    22741 ttgactcgta tattccgact agcgacctcg cgtgccacag acttggtaaa gccaatcaag
    22801 ccagccttag aagcagcata gttagcttga ccaatattcc ccatcaaacc aacaacacta
    22861 gacatattaa tgatagcacc ttctctggct ttcatcatcg gtttcaagac tgattgtgtc
    22921 atattaaagg caccagtcag attgaccttg agcacttttt caaaatctgc ttctgtcatc
    22981 ttgagcataa gagtatcttg ggtaatccct gcattgttga ccaaaacatc tactgaaccc
    23041 agttctgcaa tagcttgatc aatcatacgc ttagcgtctg caaaatctga tacatctcct
    23101 gaaatgggaa ccaccttgat accatagttt gaaaactcag cgagcaattc ttctgagatt
    23161 gccccacgac tgtttaagac aatgttggct cctgcttgag caaacttgtg ggcgatggca
    23221 agaccaattc cacgactcga acctgtaata aagatatttt tatgttctag tttcattttt
    23281 ttcctttcaa aacttctact tattttagtc tatttttcta aaagtgctac taaactcgct
    23341 tgatcttcca catgagctaa gtgagcagtt tgatcaattt ttttaacaaa acctgacaag
    23401 actttccccg gtccaatctc gataaagttg cttatgcctg cttcttgcat gaccccaata
    23461 ctttcataga aacgaacggg ttccttgacc tgacgcgtca agagctgagc aatgtcctct
    23521 ttttgcatca cagcagcttc tgtattgccg actaggggac aagtaaaatc tgaaaaactt
    23581 acctgagcta gagtttcagc tagtttctgg ctagcaggct caaggagagc ggtgtgaaag
    23641 ggacctgaca ccttaagagg aatcaagcgt ttggcacctg cttcttgcaa aagttcaacc
    23701 gctcgatcaa ctgcaaccac ttctccagca atgacgattt gtgcaggtgt gttatagttg
    23761 gctggagtaa ccactccaag ttcagaagct ttttgacagg cttcttcaat gacctctact
    23821 ggcgtattga gaactgctac catcttgcca gagtcagcag gagccgcttc ttccatatag
    23881 gctccacgct tagctaccaa ggcaaccgca tcttcaaaat ccaaggcgcc gcttgccacc
    23941 aaggcagagt attctccaag agacaaacca gcaaccatat caggctgata gcccttttct
    24001 tgcaataaac ggtagatagc aaccgaagtc gctagaatgg ctggttgcgt atagcgggtc
    24061 tgattgagtt tgtcttcttc cgtatcgatg agataacgta aatcataacc gagcacctga
    24121 ctcgctcgat caatcgtttc tttaacaatc ggatactgat catagaaatc ccgtcccatc
    24181 cctagatact gggcaccttg accagcaaat aaaaaggctg ttttagtcat ttcttacaac
    24241 tcctgcccag cgagaggctt cttcttgaat tttcttagcg gctccgtaat acaaatcttt
    24301 taggatttct tcagctgttt cttctttaga aacaagccct gcgatttgac ctgccatgac
    24361 agagccaccc tccacatcac cgtgaacaac tgctttggct agggcacctg ctcccatttg
    24421 ttcaaagatt tctaaatcag gatcttcctg cttaaaggca tctttttcag ccagttcaaa
    24481 atctctagtc aactgatttt taatagcacg aacagcatga ccaaagtgct gagctgaaat
    24541 cgtagtatca atatcccttg cttttaaaat tttctctttg tagtttggat gggcattcga
    24601 ctcttttgca actacaaacc gtgtccccac ctgtacagcc tctgcaccta gcataaagcc
    24661 agccgcagca ccttcaccat ccgcaattcc tcctgcagca ataacaggaa tagatatagc
    24721 tgtggctacc tgtcgcacca aggtcatggt tgttaattta ccgatatgcc ccccagcttc
    24781 cattccttct gcaataacag cgtctgcacc gattttttcc atgcgtttag ctaaagcgac
    24841 actaggaaca acaggaataa cgattatccc agcttcatgg aaacgttcca tatacttgct
    24901 tggatttcct gctcctgttg tgacaacttt aacaccttct tcaataacga gatccacgat
    24961 atcttccaca aagggagata agagcatgat gttgacccca aagggtttat cagtcaatga
    25021 tttgatttta tcaatattgg ccttgacaac ttctttcggg gcatttcccc caccgataat
    25081 tcctaatcct ccagccttgg aaacagcccc tgccaaatca ccatcagcaa cccaggccat
    25141 ccctccttgg aaaataggat agtcaatctt caataattct gtaatacgcg ttttcatagt
    25201 gcctccaacc ttccttgctt acgtaatagt tcgatttcac cataatttga cagtcaaact
    25261 attacctaaa caagagggag tgggtttctc cctactcctt ctactaatat tctgcttatt
    25321 ttgcttgctc ttcaacgtaa gcaaccaagt caccaactgt tttcaagtca ttttctgctt
    25381 cgatttggat atcaaaagca tcttcgattt ctgagattac ttggaacaag tccaatgaat
    25441 ctgcgtccaa atcatcaaaa gttgattcaa gtgttacttc tgatgcgtct tttccaagtt
    25501 cttcaacgat aatttcttgt actttttcaa atactgccat gataggactc ctttaaaata
    25561 aatagttttt ttataacaat gtgttcacca catgattacc taaattgtaa gaatgagcgt
    25621 gccccaggtc aagcctccac cgaagcctga tagaagaaca gtttggctac catctaaagg
    25681 gatgagacct tgttctacac actctgaaag taaaatcggg atactggctg cactggtatt
    25741 gccatattcc atcatattag ctggaagttt ggctcggtca acaccaattt ttctagccat
    25801 cttatccaaa atacggttat tggcttgatg aagtagcaga taatccaagt ctgtcacctc
    25861 tataggagat tcatcaatag tctgcttgat agacttggct acatctcgaa tggcaaaatc
    25921 aaagactgtg cgtccatcca tcttcaaaaa tgaatctgca ctttcttgat ctgaaaatgg
    25981 agaatgcaaa cctgaatgcc cataagttaa acactcgctg cgacttccat cgctattgag
    26041 actctcagct aagaaatgct cttgctcgct agcttctaac aagacaccac cagcaccatc
    26101 tccaaacaac acagctgttg atcgatccga ccaatcgact gccttagaga gggtttcact
    26161 accaatcacc aagccttttt gaaagcgacc agaagcgata aacttttcag cagttgaaag
    26221 agcaaataca aatccactgc aagccgcggt taagtcaaaa gcaaaggctt tattagcacc
    26281 aatattagct tgaacacgag cagctgtaga gggcatcatc gaatctggag taatggtagc
    26341 taggatgata aaatccagtt cttctcctgt tattccagct tttgccatca gtttcttagc
    26401 aacctctgta gccaaatcac tggtagattc tgttcttgaa atatgccttt gtcgtattcc
    26461 cgttcgactt gaaatccact catcattggt atccataatc tgagccaagt cgtgatttgt
    26521 aaccacttgc tctggcacat aatgagcaac ctgacttatt tttgcaaaag ccattatttc
    26581 aaatcctcca aaaattggta aagattagtc aaacctttac ccatgacagc aatttcttcc
    26641 tcgctcatgc catcaataat tttttctacc atggccttgt ggaagcgttt atgcagtcta
    26701 tgaatcaagc gacccttctt tgtcaaatgc agatgcacca cacgacgatc ctgttctgac
    26761 cgaactcgct caatgtagcc cttacgctct aaattgttca aacttgtcgt aacagttcca
    26821 agagttacca tcaactcttt tgacacttga cttggagtca catctggagc cttaccgatg
    26881 acatcaatcg tatgcatttc tttgatggag atatccttaa aacgactacc tctcaagttc
    26941 acttcctcaa ttacaaggac attgttaaat atagatgtta aatattcatt gattcgttgg
    27001 tagtccattt ttcatatccc tccttcttca aaaaactttt acaatcaaaa catttgacag
    27061 aaagaattat atcaaaattc aaagaatgat gcaagtattt tttattttcc tgtaaattta
    27121 ggtcttcttc tctccgaatg agctcgcact ccttctttga aatcctctgt ttgagctaag
    27181 gatttctgta ggttcagttc taaagtagcg taaccctgcc agtctttaaa ttggctctcc
    27241 caaaccaact tcttaatggc agcataggaa ttacttgaag cacgtcttaa ttttttaaga
    27301 agctgttctc tcgtcttttc aagtttttca gcttcagaaa cgcggtaaac caacccccat
    27361 tctagggctt tttctgccgt taaagcctct cctgtcatag ctaattgagc agcacgcgtc
    27421 acaccgatac tgcggctcaa gagatgaatt ccccctgcat ctggagccaa accaacacca
    27481 acaaaggctt ggataaactt agccttatcc gtcgccaaac agaaatctgc cgcaacagcc
    27541 atattcgctg cggcacctgc aacagcaccg tcaacttcca ttaaaacagg tttggctatt
    27601 tgcttgattt tataagaaat cgtattgacc aactctgcga tttttgtcaa tgatggaata
    27661 tcatcctcat ccactgcccg cttcatctct accaaatctc ccccaactga gaagaccttt
    27721 ccattggcat tgattaagat aaaatgcaca gctggatttt cttctgccaa agtcagagct
    27781 tctaaaatct cctcacacat gggaatatga aaaccatttg cgacctcagg acggttcaag
    27841 gtaaggattg ccaagtcctc ttcaagctga taaataatgt gttccatcag ggctcctttt
    27901 tattttataa gcagtttata ctcttcgaaa atctctttaa accgcgtcag cttccatctg
    27961 caacctcaaa acagtatttt gagctgactt cgtctagctt cttagtttgc tctttgattt
    28021 tcattgagtg ttaaattatt tcactgtcaa agtatatctt ttttaggagc agaaagcaag
    28081 aaaaaatcga ctgaaagtgt ctcagccgat aagaaaggct cgctttaggc tagaaagcat
    28141 cttattttct tcattgaaaa aagcctttct ttctgctata atcgtataaa atacttactt
    28201 taggagttct tatgaaagtt gttaaatttg gaggtagttc tcttgcctct gctagtcaat
    28261 tagaaaaagt tttaaacatc gtcaaaagcg attcagagcg tcgttttgta gtcgtttctg
    28321 cgcctggtaa acgcaatgct gaagatacta aggttacgga tgccctgatt aaatactacc
    28381 gcgactatgt tgcgggtaac gatattagca agagccaaag ctggattatc gaccgctatg
    28441 ctgctatggt tagtgaattg ggactaaaac cagctgtgct agaaaaaatt tctaaaagca
    28501 ttcacgcctt ggccactctt cctattgaag aaaatgaatt tctctacgat actttcctag
    28561 cagccggtga aaataacaat gccaaattga ttgctgccta ctttaaccaa aatggtatcg
    28621 atgcacgcta tatgcaccct agagaagctg ggattgtggt cacaagtgaa cctggtcacg
    28681 ctcgcatcat tccatcaagt tatgacaaga ttgaagaatt gacaaacacc aatgaagtcc
    28741 ttgtcattcc tggtttcttt ggtgtcacta aggaaaatca aatctgtact ttctcacgtg
    28801 gaggttctga tattacaggt tctatcattg ctgctggtgt caaagctgac ctctatgaaa
    28861 actttacgga cgttgatggt atctttgcag cccaccctgg tattatccac caaccacact
    28921 cgattcctga gttgacctac cgtgaaatgc gcgagttggc ctatgcaggc ttctcagtcc
    28981 ttcatgacga ggctcttctt cctgcctacc gtggaaaaat tcctctggtt atcaagaata
    29041 ccaacaaccc tgaccatcca ggtactcgta tcgttctaaa acacagtaat gatgaatttc
    29101 cagttgtggg aattgctggt gactcaggct ttgtcagcat taacatgtcg aaatacctca
    29161 tgaaccgtga ggttggattt ggccgcaagg ttctgcaaat cctggaagaa cttaacatcg
    29221 gttgggaaca tatgccaaca ggtatcgacg atctttctat cattctccgt tctcgccaac
    29281 taactcccat caaggaagaa gaaatcctgc gtcagttggt tcaaaaggct aaagtagatc
    29341 atgcagaaat cgaacacgac ctttctatca ttatgattgt tggtgaaaaa atgaagagcc
    29401 atatcggagt gactgctact gcgacacgcg ctctatctga aaacaaaatc aacatccaga
    29461 tgatgtctca aggttctagt gaagtttcta ttatgtttgt tgtcaataaa gaccaagaga
    29521 aagcagcaat taaagccctc tacaatgcct tttttggaga aagtaaggaa gactaagcat
    29581 ggcccaatca cttaacaaaa cagtactcct cagtacgaca ggcacttcct acctctctat
    29641 cgctgggaaa gttgggaaat tccttgtcgg agatcaggct ttggaatttt acccagatgt
    29701 caatgtcgaa caatttatcc agattccttg gagccatatc aatcagattg gagccaatgt
    29761 cactggacgc aaaatcagcc gccacttcga agtctttaca gacaaaggaa aattcctctt
    29821 tgcttcaaaa gactcaggtg ccattctcaa aattgcacgc gaaaaactag gcaatgacaa
    29881 ggtcgtcaaa cttccgaccc tgattcagac aattagccaa aaatttaaaa atctatttgc
    29941 aaaaaagtag aaactttagt ataatcatag caacggataa gtaggttatc ttcttctttc
    30001 agaaagtctg cgggtactgc gagcagatag gggggatagg tgaaattcta ccgttagtaa
    30061 caattacata cacaatcaag tgcacacctg tgaagttgga tggaaccgtg gccctgccac
    30121 tccaacgttt tgtcaggcgt gcttttttca taaaggagtt cttatgttag atatcaaacg
    30181 tattcgtaca gattttgaag ctgtcgcaga aaaattagct acacgtggtg tagatgctgc
    30241 tgtcttgaat gaaatgaaag aaatcgatgc taaacgtcgt aacatcttgg tcaaggttga
    30301 aactctcaaa gcagaacgta acacagtttc tgctgagatt gcccaagcta agcgcaacaa
    30361 ggaaaataca gatgacaaga ttgctgccat gcaaaatcta tctgctgagg ttaaagcctt
    30421 ggatgctgaa ttggcagaaa tcgatgctaa attgacagaa tttacaacga ctcttccaaa
    30481 tatcccagct gacagcgttc ctgttgggac tgacgaagac gacaatgtgg aagttcgccg
    30541 ttggggtact ccacgcgagt ttgacttcga acctaaagct cactgggatc tcggtgaaga
    30601 ccttggtatc cttgactggg aacgcggtgg taaggtaaca ggcgctcgct tcctcttcta
    30661 taaaggcctc ggtgctcgtt tggaacgtgc tatctacaac tttatgttgg atgaacatgg
    30721 aaaagaaggc tatactgaag tcatcacacc ttacatagtc aaccatgatt ctatgtttgg
    30781 tactggtcag tatccaaaat ttaaggaaga tacttttgaa ctcagcgata ccaactttgt
    30841 cttgattcca actgctgaag ttcctctgac aaactactac cgtgatgaaa tcttagacgg
    30901 caaagatctt ccaatctact tcactgccat gagtccgtca ttccgttctg aggctggttc
    30961 tgccggtcgt gatacgcgtg gcttgatccg tttgcaccaa ttccacaagg ttgaaatggt
    31021 caaatttgcc aaaccagaag aatcttacga agaattggaa aaaatgacag ccaacgctga
    31081 aaacattctt caaaaactca accttccata ccgtgtcgtt gctctctcta ctggagatat
    31141 gggcttctca gctgcgaaga cttacgactt ggaagtgtgg attccagcac aaaacaatta
    31201 ccgtgaaatc tcaagctgtt caaacacaga agatttccaa gcccgtcgtg cccaaatccg
    31261 ttaccgtgat gaagcagatg gcaaggtgaa actccttcat accttgaacg gctctggact
    31321 tgcagttgga cgtacagtgg ctgcaattct tgaaaattac caaaatgaag atggttctgt
    31381 gaccatccca gaagcacttc gtccatacat gggtggagct gaagtcatca aaccataaaa
    31441 aataaggttt agctatttct agctagacct tttttcgtaa ccaaatcaga taagcaccta
    31501 gtacaaagaa taaaatagtt aggcatataa tggtttcagc caataccagg taatccagaa
    31561 atggaagttt caaaattccc tgagccatct tgagcgaggt cgctgtgata atggttggga
    31621 aggtgagggc tgagagggct ggttgaaaac cttgttttaa aatgttgggc agacgagtta
    31681 aaacaaagaa aaagaaggat tgagaagcca aaatcatgac aatcaagacc caagtcggca
    31741 ggctggttcc tcctactcga actagagaag ccaagagtag agagaaagga gcacagtaga
    31801 ttccttcttg tccaagcaag gctagtggga gtggatgttt ctttaaatcg ctataaataa
    31861 ggggatagag atagaaggtc aagagaaaac caaaactcaa ggtcgcatag gcaatttcga
    31921 taatacctac cagaggatag gtcaaggcag ccactgctat ccccacatag agaaccgtcc
    31981 aacttggagt ggcatgaacc ctccgccctg aacaagcaaa cttgatggta aaaccagcaa
    32041 tcaaggtcaa atccaagaga aatgaaaacc accaaatccc ttgtgctacc aaaggaagat
    32101 aagagaatac gcgaaagaca taggtcgata aaatcatccc agccatagga aaggttgcca
    32161 ttcctgacaa aagagggggc ttggtcaatt cttgcttggt ttctttccaa ttaaagagat
    32221 gcagaattag aaagtaaatc cataaaacca aaccagtcag actaaaaaga tgggatagaa
    32281 ccggcaacgt atctaaaata agatttccag ctcctgccaa acctagcaaa caacctgaaa
    32341 atactaaggg gagttttttc atcctaacct ccaataatca tgttagtttc agtataacat
    32401 aaaagcgctt aaatgaggat ttaaaaaaac gaagtccgct tatttcagac ttcattttac
    32461 tcagatatga attaggcata aggttgcaat tctggattaa ttggtgtatt agctaagttg
    32521 ttggcatagt tacagaggat tgctaggctg acaccaaaaa ccacatccaa ggcattttgt
    32581 tgagtgtagc cagcttctaa aaactcagac aaggcttcat ctcctacacg acccttggta
    32641 ttgataactg ccaaggtaaa cttagctagg gtatccaatt taggatctgt ttcaattgga
    32701 gtacgattgc gaagagcttg aatcaagtca tcattcatct ggatttgttt gatggaaaag
    32761 gctgtgtgac ctgcgacaca gaaggcacaa ccattggtca cggctgccgt gatttgcacc
    32821 acttcacgct caacgggtgt caggctgttg cgacggtgga tagatgagac aatttggtag
    32881 gcttctaaaa cagtcggggc attggccaag agaccgatta ggttgggaat atagccattg
    32941 ttgtcttttt ctactgtttc aagaatttct ttcacttctg ctggtgctga ctctactgta
    33001 tggatagtaa atgttgtcat aagatacctc ttttcttatt attgacacta atattattgg
    33061 aaaatcttat aaaatcctga ttcctaagtt tatctaagat aaagctttat tctctcataa
    33121 gattttcgtt gttatattag tttatcacac ttccaatcac ttgcataata tatattatat
    33181 atcaggctga taaaaattat ttataggcaa aaaaatcaca cgagctgtgt gattccatta
    33241 tttgtcaaaa tactttttag tttcagcaat aacgactggc gacaagacca agagggcaat
    33301 caagtttggc agagccatca aggcgttaac gatatctgcg ataatccaga ccatatccaa
    33361 ctcgataaat cctcctaaca agaccatgag cacaaaaaac acacggtaga gccagataaa
    33421 gcgagcccca aagaggaact caaaacagcg ttctccgtaa tagttccaac ctagaatcgt
    33481 tgtaaaggca aaaagtacaa ggaagatggt caagagggca ggcccaaagt gtgaaaagac
    33541 tgttgagaaa gctgactgag tcaaggcaac cccattcaag tcaccactcc aaactccagt
    33601 taccaagatg gtcaaaccag ttagagtaca aatgatgagg gtatcaataa aggttcctgt
    33661 catggaaatc aaaccttgct ctactggttc atttgtcttg gcagctgcag ctgcaatagg
    33721 agcagaaccc agaccagatt cgtttgagaa cacaccacgc gccacaccat tttgaatagc
    33781 catccgaacg ctagcaccag caaatccacc taccgcagca aggggactaa aagctgaggt
    33841 aaagactaaa gcgattgtgc cagggatttt tccgatatta aagaaaataa ctgtaagagt
    33901 tcctaagata taaatgaggg ccataaaagg aacaacagta gttgaaacct tagaaataga
    33961 cttgagtcca ccaaagactg caatcgctac aaagacagac aagacgagag ctgtgatggc
    34021 tggcgaaatc gtcgttgtat tttggataga ttctgtaatc gagttgactt gggtgaaggt
    34081 tccgattccc aagagagcaa ccaatactcc tgctactgca aacaaaacag caagtggtcg
    34141 ccacttttct cccatcccta gaaggatata gtgcatggga cctcccgcta ctgcaccatg
    34201 gtcgtccttg gtgcggtatt tgatggccaa gagtccttcc gcatacttgg tagccattcc
    34261 aaagaaagcc gccatccaca tccaaaatag agctcctggt ccaccaacct tgatagccgt
    34321 cgcaactcct atgatatttc ctgttccaac agttgatgcc aaggctgtac acagagctgc
    34381 aaaactggat acatcaccat gtcccttatc ctggataaaa ataagctgaa aggccttggg
    34441 cagacgcaaa acctgcaaga gtcctagccg catggttagg taaatccctg ttccgaccaa
    34501 taaaatcaag aggggcggtc cccaagcaaa agcatcgatt gatttaagca attctaacat
    34561 ttccttctcc tatcgtttca accccaaaag aaagagcaca tgcaagatac atgtactctg
    34621 gaatgcttag ataaatgcta aaaagcggtc tatcctagct ctgtcctttt acctgagagt
    34681 ttgagcagtt gcctgccttg ccccttcggt gcctttacgg tctctccaga gttccgtcca
    34741 tttacagtca tggaaaatca aacgattccc cacttctatt aaacttcatt cggtgttggt
    34801 atttaattga ttctaatttt acaaaaaatg ttggcttttg tcaatgtgtt tattagtaaa
    34861 aattagttca acagttttta ctttataaag tccagaatac tgctatcctt taaaagtgac
    34921 aatagtcgca ccactgcctc cagcattttg tggggcatag ccgaaactct tgacatgttt
    34981 gtttctttgc aagtatttgg taactccttc acggatgact cctgttccga taccatggat
    35041 gatatcaact tgagccatat tgttaagcaa ggcttggtcg atgaaggtat ctagctcatt
    35101 catggcttct tcatagcgct tgcctcgaag atccagtcta gcttgaggtc ctcgcccaga
    35161 agttcgtttc acaacattga cctgtttctt cttgactggt ttttcttgct gggcttgaac
    35221 aagatcaaac tctttctctt ccaaggtcat cttaatcaag ccaacttggg cttcccagcg
    35281 accgtccttg agttgactgg tcaaggtacc acgctgacca taactgagaa ccacgatatc
    35341 atctcccacc tttggagctc gttttttctt ggccttttga aggaccttat ttttagacaa
    35401 gtccactttt tcaggagcca attttttcaa cttggccttg gcttcaatga tttcgtgggg
    35461 cttgagttgg gatttactgt ggagattttt gagaatctgg tcactttcac ttagggccat
    35521 atccacaatc tcagcagcct gttcacgcgc cttgttaagc tcggtttcct tttcacgatt
    35581 aagctcgttg tagagttttt ttagcgcacg gttcatcttg agattttctt gctccacctc
    35641 acggatattg tccaaacgtt tgcggctttc cagcgtctgc tcttctaatt gctcaatgat
    35701 acgattgacg tcattgtcct gatcgatctg ctgactggca tctcctacga taacttcaga
    35761 taggcctaga cgtttggcaa tttcaaaggc attacttcgg ccaggaacac cctgcataaa
    35821 gcgataggtc gggcgaagag ttgcagtatc aaactccata ctggcatttt gcacaaaggc
    35881 tgtctcaata ccgtaggcct tgagttctgg atagtgggtc gtcgccatgg tcttgatttg
    35941 acgcaggcga aggtcctcca gaatagccat ggcaagggct gctccctctt ggggatcagt
    36001 accagccccc aactcatcca aaagtaagag tgaatgttgg ttgaccttgc caagaatatc
    36061 cacgatattg gtcatatggc tagagaaggt agacaagctc tgctcaatag actgctcatc
    36121 tccaatatca gcaaagattt cttcaaaaat accaacacga cttcccttgt ctgctaaaat
    36181 cggcaatcct gactgggcca tgacctgtgt caagcccaga gttttgagca tgatggtctt
    36241 cccacctgta ttgggacctg taatgacaat agctgttaaa tcttgaccaa aatggacatc
    36301 atttgcgacg gcatttttga ccaaaggatg gcagacatgg agcagttgaa tctcttgatt
    36361 ttctgacagc tgaggcacga ctgcttgtct ttcttggata aatcgaacct tggcacgaat
    36421 caagtccaga tgaccgataa tccaagcgtc attagcaatc tcagccgcat gagggcggac
    36481 acgctcagaa atttcttgga gaatgcgaag catttcatag cgctcatctg ctcgcagact
    36541 agcaatttct tcgctcagtt tgactacctc acgtggttcg atatagacgg tgtttccact
    36601 agcagaaata tcatgaacga cacctgcaat cttattgcgg taggtgtttt tgactggtaa
    36661 aacctgacgg ccatttctgc tagcaacaat tccttccgtc aacatctgcg ctttttgctt
    36721 gagcaagtct tgtaaaacat cgcgtacctg actctcgcta tcatgtattt ttcgacggat
    36781 tcgcgccaat tcttcactgg caaaattttc aatgaaaccc gcatcattaa aggcctgaag
    36841 atttccttgt aattgcggaa aatcatgtaa tttctcaaac caaagggcta attcttccaa
    36901 gctgacattt tccagattgg cataaaaact ttgaagttct cggctggcaa gaagcacgcg
    36961 tttcaagagt aggaactcct cgatattgag atccgctccc atctccaacc tcttgcagac
    37021 tcctgcaatt tccttagttg agagaatagt aaaatgcggt tgctcgacga aaagagcctg
    37081 catttctttc atctcagcaa aagcctgttt gattttatct gctttggcag tcggagccag
    37141 ctgtctcaat tgctccaagc cctgctcggt caacaaatga ggatcaaaca aggccttgac
    37201 cttatcgaac tctaatgttt ctaatatttt cttattcatc tttatttcct tgtctttgaa
    37261 tgtctaggtg tggtagcttt ttacattctg atagattcga gtcaaatctg taaacaaagg
    37321 gctaggaaaa ctcctgccct ttttatccga ttaaatttgt cacccagatt tgtttgagcc
    37381 aactggttgt tatcggtatg ctctggatga tgtgttttgc gacgatactc ttttcaagag
    37441 gattttgtat aactgccatg gggatggtcg ccaagattgt caaggccatt tgcaagacaa
    37501 ataaggtcac caacatggac aagatacctg ctgaaacttg gaacaactta ccacccagtt
    37561 ttttgctagg aatcaagtgt aagagaagac caagcaaacg accaatgcta tagaaaatcc
    37621 caaatacaag caagtagccg atacctgcat aaaagacctt atccagctga aagagttgat
    37681 ccgatgggaa aaagaaagtc ccctgacctt cctgcgaatt tgcataaggg agcaataaat
    37741 ggaattgctc tccaagcccc ttataaaact ggccagccat aaaagccgat gccatggctg
    37801 aaatcaggta ataaacctgt aagagcaggc ctctccgata gccgatataa aatccccaaa
    37861 ccaagaccaa tagaagaagg aatgaaatca taaggaatcc tcaatcttgc tctgttcttg
    37921 cttacaagtc acaagcttgt gacggagttc ttctagctct tgctccttat cgtcaaattc
    37981 aatctcacgg ctgagctgag ttgataaaca gttgactgcc aacaaaagag cgattgtttc
    38041 atcatctgcg ctaggcattt gttctttaat tgcttggtat ttttctgtcg caaccttagc
    38101 gatttcctcc ataaaaaggt tatcatgttc gcttgtcaag gttaacgatt ttttcccgaa
    38161 tgtaaatttg aatcgattta gatttgccat aaaattcacc tcacgatatt ataccaaaat
    38221 tcgctaattt tgtcagtttt tacaaatttt actgcttttg tggtacaata gaaactatgg
    38281 caagtatcac actcacacca agcgaaaagg atattcaggc ttttcttgaa cactatcaaa
    38341 ccagtctggc tcccagtaag aatccctata tccgctactt tttgaaacta cctcaagcaa
    38401 cggtttctat ctatacttct ggaaaaatct tgcttcaggg tgaaggggct gagaaatacg
    38461 ctagtttctt tggctatcaa cttgtagagg aaaacagggg gcaaaatctt cctttaattg
    38521 ggacagatga ggtgggaaat ggttcctact ttggtgggct tgcagttgtg gctgcctttg
    38581 tcacatctga ccagcacgac tttttacgaa aactcggtgt gggggattct aagactctga
    38641 ccgaccaaaa gatccgtcag attgctccta ttctcaagga aaaaatccag caccaggcac
    38701 tccttctctc acccagcaag tacaacgagg tcatcggaga ccgctacaat gctgtttcgg
    38761 ttaaggttgc cctccataat caggctatct atctcctcct tcaaaaaggt gttcagcctg
    38821 agaaaattgt gattgatgcc tttaccagtg ctaaaaatta tgacaagtac ttggcacaag
    38881 aggccaatcg tttcagcaat cctatcagct tagaagaaaa ggctgagggc aaatacttgt
    38941 ctgtcgcagt ttcttctgtc attgcgcgtg atctctttct ggaaaatctt gaaaatttgg
    39001 gacgagaact gggttatcag ctcccaagtg gagctggaac ggcttctgac aaggtggcta
    39061 gccagatttt gcaagcctat ggtatgcagg gactcagctt ctgcgccaaa ttgcacttta
    39121 aaaacactga aaaagcgaaa aaacgcttag aaaggtaagt tatgaattca tttaaaaatt
    39181 tcttaaaaga gtggggattg ttcctcctaa ttctgtcatt actagcttta agtcgtatct
    39241 ttttttggag caatgttcgc gtagaaggac attccatgga tccgacccta gcggatggcg
    39301 aaattctctt cgttgtaaaa caccttccta ttgaccgttt tgatatcgtg gtggcccatg
    39361 aggaagatgg caataaggac atcgtcaagc gcgtgattgg aatgcctggc gacaccattc
    39421 gttacgaaaa tgataaactc tacatcaatg acaaagaaac ggacgagcct tatctagcag
    39481 actatatcaa acgcttcaag gatgacaaac tccaaagcac ctactcaggc aagggctttg
    39541 aaggaaataa aggaactttc tttagaagta tcgctcaaaa agcccaagcc ttcacagttg
    39601 atgtcaacta caacaccaac tttagcttta ctgttccaga aggagaatac cttctcctcg
    39661 gagatgaccg cttggtttcg agcgacagcc gccacgtagg taccttcaaa gcaaaagata
    39721 tcacagggga agctaaattc cgcttctggc caatcacccg tatcggaaca ttttaagaga
    39781 cctaagaggc cgagaatcac caatctcagc ctcttcttct atcgtgagaa gtgattgttt
    39841 attgacaaat actcaacgaa aatcaaagaa caaactagga agctagccgt aggctgctta
    39901 aaacagtgtt ttgaggttgt ggatagaact gacgaagtca gctcaaaata ctgttttgag
    39961 gttgcagatg gaagctgacg tggtttgaag atattttcga agagtataaa ataaaaacaa
    40021 tcccaactct cacctattca tgcaaaggaa ttttatggaa gtttattttt caggaaccat
    40081 tgaacggatt atttttgaaa atcccagcaa tttttatcgc atcctcctcc tagaaatcga
    40141 cgatacggac gcagaggatt ttgatgattt tgaaatcatt gtcacaggaa ccatggctga
    40201 tgtaattgag ggcgaagact atactttttg ggggcaaatt gtccagcact ccaagtatgg
    40261 agaacaactg caaatcagtc gttatgatcg cgcaaaacca actagtaagg gcttggtcaa
    40321 gtacttttca agtagccatt tcaaggggat tggtctcaag acagctcaga aaatcgtgga
    40381 tacctatggc gaaaatacca ttgacgaaat tttgcaacac ccagaaaagt tagaaggcat
    40441 cgcaggactc tctgccaaaa atcgcgaggc tttcgtctcc actctccgtc tcaactacgg
    40501 aacggagatg gttttgtcca aactagccaa ctacggcatt cccaacaaac tagcctttca
    40561 gattcaagac ttttacaagg aagaaaccct tgatgtggtt gaaaattatc cctaccagct
    40621 ggttgaggat atcaagggtt tgggctttac cattgctgac caactagctg aggaactagg
    40681 catcgaaagt caggctcctg aacgcttccg cgccggtcta gttcacagtc tttttcaggc
    40741 ctgtatggaa acaggggaca cctatgttga agcacgggat ttgctggaac aaacccttac
    40801 tctccttgag tcttcccgtc ccgtggaact agaccccagc caagttgccc aagagctctc
    40861 ctacctgatc gaagaagaca aggttcagca gattgatacc aagatctttg acaacagcct
    40921 ctttttcgct gaggaaggca tccgcagtca cttggttcgt atccttgaaa aaggaaaaca
    40981 gaagagtcat gatttagaaa ccattcaaaa acatatcact actatcgagg aagagctggg
    41041 aattgagtat gataacattc aaaaacaggc tatctgtgat gctatccaga ataaggtctt
    41101 tatcctgaca ggtgggcctg gtactggtaa gacaactgtt atcaatggaa tcatcgctgt
    41161 ttatgccctg ttagagggac ttgacttcag gaagaaaagc aatctgccta ttcttcttgc
    41221 tgctccaact ggtcgagctg ctcgtcgcat gaatgaattg acaggtttgc ctagcgcgac
    41281 catacatcgc cacttgggaa tgacaggtga cgatgatacc agtcatctgg aagattacct
    41341 agatgctgac tttatcatcg tggatgaatt ctctatggta gatacttggc tggccaatca
    41401 actcttctcc aatatctctt ctaacagtaa gatcctcatc gtaggtgaca gtgatcagct
    41461 accttctgtc agtcctggac aggttctagc ggatctgctt catattcctt tgattcctca
    41521 gactcacttg gaaaaaattt atcgacaaag caaagaatca accatcgtca ccctagctag
    41581 tcagattcga cagggcatct tgccagctga tttcacccaa aaaaaagctg accgttccta
    41641 ctttgaaatt gctagtggcc atattcctgc caccattgaa aaaatcttag gtgccgccct
    41701 cagaaatggt attcctgccc gtgatatcca agttctggct cctatgtacc gagggacggc
    41761 agggattgat gctatcaatc agctcatgca agacctgctc aatcccccac aaaaagatca
    41821 actcagtttt gaagctcctc agtgccacta tcgtaaggga gacaaggtca ttcatttggt
    41881 taacgatgct gaaatcaatg tctttaatgg ggatttagga gctatcacag acctgattcc
    41941 tggtaaatac accgaatcga aacaagacga gattgtcatt gattttgatg gtaatgaagt
    42001 ctcttacccc cgtaacgaat ggtacaagat tcgcttggcc tatgccatga gtattcataa
    42061 gtctcaggga agtgagttcc cagttgtcat cctaccgatt actagtgcta gccgacgtat
    42121 gctggagcga aatctcatct acacagccat tacacgtgcc aaaagcaaac tcatcttact
    42181 aggcgaatta caagccttcg actatgctac ccaacacatc ggaactgccc gaaaaaccta
    42241 tctgattgaa cgcttcagtg atctactgga gaatgttgaa gaaaagcaac aagctgtctc
    42301 tgaaacagtc acatcaagtg cctctgaaca atcctacatc ctaaccgaag aaaactggga
    42361 cagcattcca gccatgattg ggattacaga cacagacctc aaagagattt ttggaaaata
    42421 gtgcatcaga aaaaccacca attcaggtgg gttttctgtt tattaagatt attttactgt
    42481 tgctgtgctt gtaatcaatt caacagcttt tttgatagtg atatcatgtt tcaacatgtc
    42541 agctgaaagc aagttttgaa cttgtgcaac ttccatgttg tagtctgctg ccaattgctc
    42601 aacttctttt tggatttctt cttctgaagc atcaaatcct tcagctttgg caactgcttc
    42661 gataacaagg ttagtcttag tacgtgactc agcttctgct tggtattggt tgtgaaggtc
    42721 ttcttgagta gttccagtaa tttggaagta catgtcaggg ttgatccctt gacgttgcaa
    42781 gttcccaagg aattcattta ctgaacggtg aacttcttcg tggatcattt cttctggaag
    42841 ttctacgatt tcagcatttt ctacagctgt atcaattgct gcaccttcaa ctgcatcttt
    42901 gtaagcttct tctttagcag cagccaattc tttgcggtat ttttctttca agtcagcaag
    42961 tgtttcaact tcttcatcaa tgtcttttgc aagttcatcg tcaagagctg gaacttcttt
    43021 agcttttact tcgtggatag ttgtcacgaa tttagcttct ttacctgcaa ggtcttctgc
    43081 ttggtagtct tctgggaatg ttacgataac atcaacggtt tcgccagctg agtgacctac
    43141 caattggtct tcgaaaccag ggatgaattg acctgaacca agtccaagtg agaagttttc
    43201 accttttcca ccgtcaaatt caacaccgtc gatagaacca acgaagtcga tcacaacagt
    43261 gtcgccgtct tcagcagcag cttccttgat aaccaattca gccaggttgt tgcgttcacg
    43321 ttcgatacgc tcttcgacat cagcgtcagt tacttctttt tctacatcaa ctgatacttc
    43381 aaggtttttg tagtcaccca attttacttc aggttttgta acaacttcag cagcgataac
    43441 ccagtcttga cctttttcca ttgaagttac gtcaattttt ggttgggcaa ccacttcaag
    43501 accagcctct tttacagctg cttcataagc gtttggcaaa agagcgttca taacgtcttg
    43561 gtaaagtgat tcttcaccaa attttttatc gaagatagga cgtggaaggt gacctttacg
    43621 gaaacctgga acattaagag atttcttcac tgacttgaag acacggtcca attctggttt
    43681 gatttggtct tgagagatag tgaaagtcaa gacaccacgg tttgtttctt tgttttcaaa
    43741 tgatacagac attctgtcat ttctccttaa aattttttaa atacagtcta ttataacatt
    43801 ttctataaat aaaatctaga ctaatgcaga caattataga caacaagcct ttttcctaac
    43861 taaaacactc ataaagtata gacaatttta gactactttg gatatctttt ggttagtcat
    43921 tttccaaaac taatttatct aatttttaag ttatatttga cttcatcttc tcagtaacat
    43981 gagtataaac acttaaaatc tttgtttcat tagtataatc tacacgatcc attatcgctg
    44041 ttataggtac ttccaattca gcaagcaaac ttatatgcga atatctaaaa acatgagcag
    44101 tcaatacaaa atcatctttc ttaatttcac ttttcctaaa cctgtttttc aaaaagtaat
    44161 tgaaacaagt tatcattaag ggagaaccat tatttgtaaa tatataatca ccttcttcta
    44221 aaagaagata ttcttttaaa atttctaaca ctctatcact aataccaatt actctatatg
    44281 aagctaaact tttcggacta tccaaaaaca cttcgttatt ggacgattac attatagtaa
    44341 aacgaaataa gaacaggaca aatcgatcag gacagtcaaa tcaatttcta acaatgtttt
    44401 agaagtagag gtgtactatt atagtttcaa tctactatac aagacgaaat tgaagaaatc
    44461 tttccattat aaaacgcata ttatcaaggt ttttaaacac ctaataatat gcgttttttc
    44521 ctattttaaa gacttttatc cacctattat acaaagttaa gtatccatca cagtttacaa
    44581 ttagccttca ttacctaacc cattcaccat ccttcaagag agtaaccttt aagaaccgaa
    44641 taaataaatg gcaaatttcg ttcatttaat ttaactgcac tgttaatttg attagctcca
    44701 tctcctaaag tatgcactcc tactacacgg tgactagcat cataaactgt agatccacta
    44761 gacccctcta aagtatcaac ttggtaatcc aagaacatgc catcatcact taaaacttgt
    44821 tttttatctg tatacatttg atgaacttta aaattatatg atggatagcc tgtgatagtc
    44881 acagttattc ctgtcaaatt tttttgacta gtaggaagac ccaaagtccc taattttgca
    44941 ccaatgggct cttctagaat taataaagcc aagtcatatt cccttgcatc cttagaattt
    45001 aaatttctaa attccttcaa ataacgaact tcctttactt tgatctttcc aaatggttct
    45061 tgacttggac taacagtcgg aagaacataa atatcatccg cttctttccc atagtcatgt
    45121 ctgtagtagt tgtgagccgc tgtaattaac acattatctt taataaaatt cgcacttccc
    45181 ctcccttcta cattcattcc atcggctact ccataatact tagataaaac catagctgaa
    45241 gtcgaatacg gatactgtaa agtattatca attttaatca aatcatcatt accgataata
    45301 cttctgattg cttttggtag tatgaaccat atgttggtga aatctcagat aatgaagaat
    45361 cattagatcc tggacctttt tctagtgtct cacttacctc atattcttca cccgtactag
    45421 aaataacact caaagcagat actgtcgata actggctagc caataaagta ctcgcaataa
    45481 ttgaaatacc caatttttta taaacagttt tcttcattat tgtatcctcc taatgtaatt
    45541 atagcgtact attctaaatt tcttaatcta ctatagaatc aagaaatcta ccaccttctt
    45601 taaataccct ccattatcac ataaacaggt aaacttttca attaatgact gcgcttttca
    45661 atcacgctag aggtacttac ttgcttcttt gatactaagt tcagccattc tttccttgtt
    45721 tttctcaata aagcatgtta cccaagtggg attcgttttg gagtagtctc gcagagtcca
    45781 gccaatggct ttattgataa aaaattctgt ttggttcaag ttatgaagta gaatcttttc
    45841 cattaattga gtattggtct tctcttttct taacaactgg tggtcaatag cgacacgtct
    45901 cagccagata ttatctgata ggctccattt tatactcaat gaaaatcaaa gagcaaacta
    45961 ggaagctatc tgcaacctca aaacactgtt ttgaggttgc agatagagct gacgtggttt
    46021 gaagagattt tcgaagagta ttaagattat ttcttctagt tcagggtgtt catacaccaa
    46081 actccctact actcgatcta ggatatctac cgtgtcccac caggattttg tcacgactaa
    46141 ctgctctagc ttaggcaaat cggtttcctt tagataagac tgcattgctt tcaaatagtt
    46201 agcagccaca tattggtatt ttctaggctc cttttcccag caagtgtctg caaaatccca
    46261 atcgataatc tttgtttttt tcgcttctgg taaatatttt tatagagttt atttctttca
    46321 ggcaccgcaa tacctagaaa agaaaattga tggcgcatat aggcttccat gggccttgct
    46381 tttttagagt cttttgctgc ttctagctcc tcaagtaaat ctgctaaact catctaaaac
    46441 tcctcttgcc ccaccaaatg gtgctgaaag gcatagacag ccgcctgggt acgatcgctg
    46501 acttcaagtt tggcaagaat attggacacg tgggtcttga ccgtcttgag agagataaag
    46561 aggtcatctg cgatgcgctg attttcgtag cccttggcga tgagttggag aacatctcgc
    46621 tcacgcgcag tcaattcttc atgaagttcc atatgattgc ggtggtattc aaccttcttg
    46681 ctaacctctt gctcaatggc cagctcgcca gcagctacct tactgacggc atgaagcaat
    46741 tcatctgcac tagaagtctt gagcatatag cctttggcac cagcatctaa gactggcatg
    46801 attttttcat tgtccaaata agaggtcaca atcaaaatct tggcttcagg ccattcttta
    46861 aggattgcta aggtcgcgtc aatcccattc atctcaggca tgacaatatc catgacaatg
    46921 acatctggac gcagttccaa ggccaagtca atcccttgag acccgttgga cgcctcaccc
    46981 acaacttcta catcgtcttg gaggtcaaag tagcttttca agcccaaacg gaccatttca
    47041 tggtcatcta ctagtaaaat tttcatcttt actcctttat cattccttat ctaacagggg
    47101 aatacggata tcaactgcca gcccttgctt gggagctgtt aataactgaa ccgtccctgc
    47161 catatcttca acccgctcct tgatatttcg cagtccataa ctcaagtcgt ctaagcttcc
    47221 taaccggaaa ccaatcccat tgtccaccac cttcagttgc aattcaacat ctgtctgata
    47281 gaggtagaca tctaggcaag atgcctgggc atggcggagg gtattgctaa tcaactcttg
    47341 caggatacgg aagatatgct cctcgatttt cttaggcaat ttcgtcatat tctgcttgag
    47401 actaacccta agatcactct tgtcctcaag ctcttttaag agaatctgaa tcccttctat
    47461 caagctcttc tgctccagtt caactggtcg caaatgcaag agcaaaaccc gcaaatcctt
    47521 ctgggcagtt tctaaaatag ctgtgacact ctgcaactgg gtctgcatct tttctctatc
    47581 caatttcaaa gcctgctgac tgatacccga taaaataatg tgggccgcaa acaactcctg
    47641 actgactgta tcgtgcaaat cccgagcaat tcgcttccgt tccttctcga taatttcctc
    47701 ttcctgatca aggctatgat tttcagcttt ttgaagagcc tctgtcaaaa ggttaagttt
    47761 acctgataag gacttgaaac tggcatccaa atctggatct acaacctgaa ctacttcttg
    47821 ccctgccaat aaacgcttga gattagcctg catttttctt agagaaagct cttcgatccc
    47881 tcgccaaaac agggctaaga gacaggtcat ggacatgctg aaaaccaaca ataaaaagac
    47941 aaatttttct gttttttcga catcgtacaa aaagatagac cagtcaaaat caagtatttc
    48001 cagcaagctg tgggagaaaa aaaagacaaa taggaaggag gtgagagcaa taatgacata
    48061 ggcttgtttt ttcatcctct aaccacctcc acatcaccaa tcatagtggt caagaaaatc
    48121 ttgacactct tgttactctt gagatagtct tttgtttctt gatgatagtg ttcattgcgg
    48181 agggctcgct tgggctggtt gaaaaaagtc aaatccccat agagacagtt aacgctgaga
    48241 ctgacttcca catctacagg tacgatgatt ttggtcgttc ctaccatctt tctgaggata
    48301 atgacattgt catgattggt taagatgact ctctccagat gaatagtgtc cttgcccatg
    48361 aagcgaaaga gattgatatc atcaaattgg caagtctggt agcttgaaaa atgatgaaga
    48421 tttccaaacc aacgattttt ctccttctta accgtcacaa cctcttcaaa aaccaaattg
    48481 gtctgctctt tttcctggtt catcatcggg taaagaagaa agagactata gataaccgca
    48541 acaaaaatag ctagaatcac aaaaggattg agcataacga tgaaaaagaa gagaatggtt
    48601 gccgctacta aaagaagatt attcccctct ttaccagtat agtagcgaat caaaagcaaa
    48661 aagaggaata gtatcagcag aaaacgcgaa aaatgctctg ataccatcaa aatcagagct
    48721 cctgtcagaa gacaggcttc gataaataaa aagattttaa attttctcat aggttcatcc
    48781 tctcccttct attttatcac aattcaaaaa agtcacctca gtctgaggat ggaaaaaaag
    48841 gcgctggtta cgcctttttc atctgatcct ttgcttcttt taattttcca taaagaagat
    48901 agtctacttt ttgtagatct gctatggtgg cacagttaag ggaacacata atcaagcgta
    48961 gatctgcttt ccagccttgg acaatgccaa tcacttcttc aactgtgtag gtttcaacca
    49021 attccagaac ggttcgtgac aatcccacag ccttagcacc aaaaaccaag cacttaatca
    49081 tatccagcgg attccgaacc cctccactaa ccaagagttc gaccttatct ttccattctt
    49141 gggcattgag aagggcctgc atggtagact gaccccattg attgaggtaa tcacgctggc
    49201 cactacgacg gttttcgata taggcaaagc tggtgccacc acgacccgat aggtccactg
    49261 tacgaacacc gaattcatag gctctttcga ttgtcttggc atccattcca aagcccactt
    49321 ccttgaggac aataggaacg ggaatttgct tgctataatc tgctagatgc gattgccagc
    49381 ttctaaactt cctttctccc tcgggcatga gtaattcctg catgacattg acatgcactt
    49441 gcaatagaac aggattcatc tcttctacag tctgaagtcc taactcgaca ggtttgtcca
    49501 atccaatatt ggttccaagg aggagattgg gatgactaga cttgacagaa aaagaatcat
    49561 ccgttggatt tttgagggct gcgctataag aacccgttac aaataaaata ccacaggatt
    49621 ccgccacctg agccagcttt tgattgattt ctcttccctt attacttcca ccagtcatgg
    49681 cattgatata aaaaggaaag tcccactttc gaccagcaaa ctctgtcgaa agatcgattt
    49741 catccagatt gtaaagaggc aaggaagaat gaatcagctc cacctcatca aagctattat
    49801 aggaactttt ctgctcaagg gcatagagga tatgctcgtc cttacgattt gtcgtcatgt
    49861 cctatccttt cttgatataa gagctcaatc cccagatcgg cccaacgatt ttttaaggtt
    49921 ttggttgatt gcgcatcaaa actcagggcg atgccacagt caccaccacc agcaccacta
    49981 ctcttggcaa cggcctgcaa atcttgactg gcttctttca actgtctaag caaaggcgtg
    50041 taaatatctg tactcaagcc ttctaaaagc ttgctggcta cttctacttg ctcgataatc
    50101 ttttctgatt tcccctgttc caaggcttcg accaaagaaa ccaccgtttc ttttgaggaa
    50161 cttaaaaaat tttgattgat attttgcttg atttgctgga ccatgtgact cgatacagcc
    50221 acttccttgg tccatcccac taagaaatca cattctaaag ttggtttcac ttgtgaaatt
    50281 gaaaagcccc aatcacgctc cagaactgtc gccaagtttt cttcttctaa ccaagcagcc
    50341 accttctggc gatcaaatga ctggtagaga accaaatcct ctgccacaat acaggcaagg
    50401 tcgcccatgg aaccattgtc tcctcgcttg agcaagacag cgctagtcag cttgaacaag
    50461 agctcctgat caacagaaac atcatacaga gccagtaaag ccttgacaac caagacaacg
    50521 acgctgccac tagaacctag accaaacttt ttcccttctc gttccatttt gccacagatt
    50581 tctagggaaa aagatcttaa attctgaccg cgaacagcga ggaagtctcc catcaaagca
    50641 atcgtttctt gaatcaagct gtagtcagga ttgggcgtta agtccactgc gaaatcaaac
    50701 atatctgaat agatacggta gctgtcagaa aaagcaatct cagccctcat atagatggga
    50761 atatccttta tcaaagctaa ctgccctggc tctaaaatag catattcacc tgcccaatag
    50821 agttttccgc aagttttaac agcaatcatc ttgactcaaa tcctttgttt ttgacacaat
    50881 caagcgataa cgctgaccga aaatttctga caaatgctcc aagtctttct cctgacaaaa
    50941 gaccttaaca ttgggaccag catccatggt aaagtagcag gcctctcctt tctcacgaag
    51001 ctggcgaaca aagtccatag cctcataaga ggcatccgtc agataagaaa aggctggact
    51061 agcagtcttt gtcgtagcat gcatagccag ggcatttttc tccgttaatt ctccaatctt
    51121 ggcaaaatca ttttccttga gataaatcag catatcctga tagtccttct cagactgacg
    51181 aacccagtcg tcaaaagtcg tcgaggtttc cacacaaagt ttcatcccgt cacggctaga
    51241 gattggtttt ttcttgtcct ctagcaccaa cataatcata gctagtttca agtctgtctc
    51301 tacagagtaa atttctccac tatccttatc ccaggctcct agcggtccat aaaaactccg
    51361 agaagaagag cctgaggcaa acttggcttc ctgcgctaac tgacttctat ccaatccaag
    51421 cttgaaataa gcattacaag ccttgaccag ggcggacaaa ccactagaac ttgaggacag
    51481 gcccgctgca gtaggcatat tgttttgagt atcgatacgg acaaagccct caccagctgg
    51541 acgataacgg tcaataatct tactcatctt ggcatgctcg acctcatttt gtagctgacc
    51601 attgatgtaa aattcgtcag ctattacatt ggctggtaaa ggcgacaagg tcgtctctgt
    51661 atacatattt tccaaagtta gagaaatact gctagtagca ggcaccatct ctttttcttt
    51721 tttctttccc caatatttga taatagcaat atttgcgtag gaacgtactg tcacaggctc
    51781 tctatccatg tctgaacagc tcctttctct tctaatcttt ctgctagttc ttgtgcgtgt
    51841 gtcaaattgg ttaccaaggc tatgatacaa cctcctagcc caccaccgct catcttggca
    51901 cccagagcac catggctaag agtcgtttca accaaaaagt ctgcctcagg gctactgact
    51961 ccaatttctt ttaaatgtaa atgcgcttga ctgaggattt gtcccagtcc ttcagcatct
    52021 ttttgtgaaa tcgcaacttc tgcttgctgg gttaattctc ccaaggcatg caaaaacggt
    52081 agggcatcct tgcccttatt ttgaaccact tggatggctt cacgagtatg accataaaca
    52141 cccgtatcgg caatcaccaa ataggcggat aaatccatct caagttctgt aaatcctacg
    52201 ttcttgataa agcgaatagg ttggtcactg agacaggtct tagcatccaa accactagga
    52261 ttcatatggg caatcatctc agctcgattg accaagattt ctagtacatc atgaggcaga
    52321 tcagcctgat agtagtcaaa taccgcacga atggccgcta tgctgatagc cgctgacgaa
    52381 cccatccccc gtttctcagg gatagccgag tcaatctcac aacgaatgca ggcttctgtg
    52441 atatccaaat actccagtga ggcataaacc gccatggaca aggtatcctc ctcataaagg
    52501 cgccaaggac tctctgcagg aactacctta caggtcacct ccacctccaa aagaggcagg
    52561 gaaatggcag gataaccgta aacgaccgca tgttccccta ttaaaattat cttactatgt
    52621 gcctgaccga caccaacttt ttttgtcatt ttttcctttt actagacgaa aaaacgtctt
    52681 atttttcata caagtattaa ttctttccta tctattttat tatattttca caaaaaaagc
    52741 gattgtttcc attcacaatc gcttctttca ttattgaacc cattcgccat tatagttgac
    52801 agaatagcca tctacggtcg tattcactgc caaggcacct gagctataag cgtagtacca
    52861 tctgccattg acctggaacc aacctgtcgt catagaacga cgaaagaaac tccataccgt
    52921 taagtaaaga ggaaagtcgt gagggatcat gcgccattga caacctgttt tagtgacgta
    52981 caaagtctca ttaacaagta ctcgtttcgg ccatttatag gtgcggtgtt tggagaaata
    53041 gggttcaatc ttagcccatt cttgatcgtt taaatcagta tcatatgctt tgcgtgtcat
    53101 aactctagtt taacattttt tgtgaataca agttctaaat aatcgaccac gaaaatttct
    53161 taagtggaaa acgccttatg aagtatgcta cgggaaactt atgcacttaa tttgacaatt
    53221 caagatgtaa aaatatatac tatagtagat tgaaactaga atagtacacc tctacttcta
    53281 aaacattttt agaaatcgat ttgactgtcc tgatcgattt gtcctgttat tattttattt
    53341 tactataata tttgacaagt tatcctaaaa gtattattat gttgttgtgt tatagattga
    53401 ttgaatctaa ctaaaggatc ctattcaatt actagaacta tcacatactc aaggtcagct
    53461 cacagatgag caactatttt ggttacaatg tctactaaat ttaagtcaaa caaataattt
    53521 agtcaaaatt aaaaaaatag aggaacataa atatgattac aaaacagaat gtaatagtgt
    53581 tctacgattt ttactagata aaactgtaaa ttctgaagga aggatcactt cttcaacaga
    53641 atttggaaat ttcgtaagta atttatcatt ccaacacgga atagctggac tactgtttcc
    53701 tctaaataaa ttgtaccccc cagaactgga ttctaaaata ctctctatca tcaagaaggc
    53761 agtgacaatt agaacgacac acatatgaat atcaatactc actgctattt ggtgatgcag
    53821 gctatctatg gttactccta catttatttt ctatcagtaa aaatcaatac tatctacaat
    53881 tagcaaacgt caccgctaag aaattaatag agaattatga tactctagaa gaaatagact
    53941 ttgcattggg aaaatctggt gtcctattat cattaataaa atactatcaa tttaccaatg
    54001 acaatactct taaaactttc atccacaata gtatatgggg aaatttatca ttatttccta
    54061 caaagagata cagccaaaga aagcatttta gactatagct ttgctcatgg atattgtgaa
    54121 attgcatatg ctttatttgc ctattctaaa gtcttagaac cttctatgtt ctataatgat
    54181 ctccatacat tccatgctga attaaaaaaa ttattagaaa aagttacttc taatactgaa
    54241 aatttaggaa atttacaact ttcttggtgc gaaggaattt ccggaataat cttatatctt
    54301 tgtatgtacg attgtgacgg aaacaaagat attattagta aatatcaaga atttgttttt
    54361 aaccatcatc taaaaatgat gacaggatat tgccacggaa taactagctt actacaaacc
    54421 actgtctaca atcaaaacaa attactgatg aaaaaaatcc aacaggtaat tttagcatgt
    54481 tctgaacgag atgatcacgg tttactgatg tttcaaggag atagtggtaa agcagatttg
    54541 tttgacttcg gaataggaag cagggggtat attggtgtct attaaataat aaattcccat
    54601 tcgatgtgca aacataagga gaaatgtatg aaattatttt ggacaaacaa catatataga
    54661 cagttgctgc taaacagctg tttttcatca ttcggcgaca gtattttcta cctcgccatt
    54721 atcaattatg tggctcagta caatttcgct ccgctagcga ttttactgat ttccatttca
    54781 gagatggttc ccctactatc gcaactcttt ctcgggattc taggagattt tcaagaaaat
    54841 agagtcaaac acgcactctg tattgccaaa atcaaaatcc tgctctacgc tattttgaca
    54901 gtatttctcg tcttgtcgcc cttttcatta gtttcagtca ttatgattgt catcatcaac
    54961 ctcatctctg acaccttgag ctacctgtct gcctacatga tgaacgccct ctacatcagt
    55021 gtaattaagg atgacctgca tgatgccatg gggttcaggc agtctctgat gagggttgtc
    55081 cacattgtcg ccaatctggc tggcgcattc cttatcaatg ttataagtat tcaaactatt
    55141 tcccttatca acactctgac ttttgtcatt gcctttttgg gcctgtatgt tattcgacat
    55201 accttgtatg aggttgaaaa aaggattgaa atgtcacata cagcactgag ttttaagaaa
    55261 tattttcaac atcttaaaca gtcgctggct gtgctcctga ggttaaaaga taccgtcata
    55321 ctactgtttc tgacgaccag tatgattgcc atcttggatg tgtcccctcg gctgattgcc
    55381 ctccgcttca tccaacagac actagcacaa ctgagcattg ggcaactctt cgccctgctc
    55441 tccatcatca tgtcttgtgg agctatcctt ggcaatatga ccagcagtaa tctatttaaa
    55501 aatatccgtt tcacgcacct cttggttttc tgtgagattt ccctattggc tctaataact
    55561 agtatccttt gtcaagccta tatcgtaatt ttcgtgacca gtttcatcag ttctacgatt
    55621 atcggcattc tcagccctcg cctacaagca gctgtctttg cccatatccc cagtgacaag
    55681 atggggacgg tgggctctgc tctgagcaca gtagacattc tcgccccgtc cctgctctcc
    55741 ctattagccc tatccatagc atcgggcgtt tcggtgcagt tagcattgat atttttgtat
    55801 cttattttga ttgctcttat cttttgtcaa tggttagtca agttcaacac tcataactaa
    55861 cgaaaaagca tgtgtagatt tcacatgctt ttaatctccc caatcgtcag gtcaagtaca
    55921 acaaagtcac ttctttgatt aagcgagtgt tctaatataa ttataagcgc cctgtcatta
    55981 ccgaacccat tcgccattat agttgacaga atagccatct acggtcgtat tcactgccaa
    56041 agcacctgag ctataagcat agtaccagtt gccattgacc tggaaccaac ctgtcttcat
    56101 gtctccatta cctgcattta ggtagtacca agttgaacca tcttgatacc aaccagttgc
    56161 catagctcct gatgaacgga gatagtacca tttgttccca aggttttgcc aacctgtttt
    56221 catatcgcca tttggctggt ctaaataata ccaagtggta ccttcctgat accagccagt
    56281 ggccattgct cctgaggaac ggaggtagta ccatggagca ggtttgcttc tatcaatgtc
    56341 aatagtaaca tgaaaatctt gagtccaacc cttagcaact tcaccaattg gtagtggatt
    56401 gtaagaatca tcaccaaaat ttcctagctt atttaaataa taccaattgc cgtcttcata
    56461 aatccagcct gtctttacag cataattatt atcaaaataa taagttctct tttcagcaga
    56521 tagaggatat tgttcaccgt atacttttcc tgtattttca gacgtttttg cctctagtac
    56581 ttgtttatct gtttgttcta gcaaagcacc atcttgtcca aaatagtacc acttctcctg
    56641 aaggccaatt tcgaagactg gacgattatc aaataaatca tcacgataac ctgttccagg
    56701 aatttctaag tattgccaac cgacaaccat ctctccaata tcaccaaaat agtaagtttt
    56761 accgtctatt ttatgccaat agattgcttt atgatcatct tttacataat attttctatt
    56821 atccttatca acaaatcggc cacctgtggt attcgcaaat accgtatttg tagctagcaa
    56881 accaaagaaa aagactgcta gtagaacttg catcattttt ttcaaaagtt tcatttatat
    56941 atcctcctaa aacgattgta gcaaagacac gactgcatgt caatatataa aaactcctca
    57001 aaaaagcagt tacacaactg caactgcttt tctattcttg catggtgtaa ccaacaccac
    57061 gcacggtttt aatgtagctt ttttgtcctt taacatcaag cttgctccgt agatagcgga
    57121 tatagacatc tacgatattt gtctcggtcg cactttcata cttccaaaca ctttccaaca
    57181 attgctcacg agtcaatact ttcttgcttc ccataagtgt cgccaaaagg tcatactcac
    57241 ggcgggtcag agcaatcatc tcttcaccac gataaaccgt gtgatgttca acatctatcc
    57301 taagattgcg gtaggtcctt ggaactttca tcagactgca gtgttgatca atgaagtccc
    57361 gacctcggaa gatcgccgaa atacgcgcta ccagattttc gataaagact ggcttataga
    57421 tgtatgaaac tgcaaaacgc tgaacaactt ccagctcttc ttgcaagtct tcccaatgat
    57481 ctaaaatcat gatgactgag gcaggtttag ttcgactcaa tttttctgca aaatcctgag
    57541 ccatcatatc tcccagatta acgttcaata aaatcaaatc atagtctgtc tgaagagcca
    57601 tggaaagggc tttttgcccc tcctctacca gatcaacccg atactgctct ttctggagtt
    57661 ccaaacttaa aaaatgagct agatttcgtt ctttctcaag taataaaatc cgtttcccca
    57721 tggctgacct acttattttt cgtcatacca agagtagtgg aaggttcctt ctttgtcttt
    57781 acgttggtaa gtgtgagcac caaagtagtc acgttgtgct tggatcaagt tagccggaag
    57841 gtcagctgaa cggtagctat caaagtaagt aatagctgct gagaaagttg gcactggcac
    57901 accagcttga accgcaagag ctacgatatc acgcactgct tgttgatact tagcagtaac
    57961 atccaagaag tactcgtcca aaagaaggtt ggcaagatct gcatcgcggt tgtaagcatc
    58021 tgtaatcttt tgcaagaaac gagaacggat gatacagcca tcacgccaga tagatgcgat
    58081 atctgcaaat ggcaagttcc agttgttttc tttagaggct acacgcaatt gagcaaatcc
    58141 ttgtgcgtat gaaatgattt ttgagaagta aagggcttga cggatttttt caatcaattc
    58201 agccttgtct ccttcaaagt tgaaggcagc tggttttgga agcaccttgc tagcatgtac
    58261 acgttcttct ttgtaagttg aaatgtagcg tgcaaacact gactcagtaa tcagtgacaa
    58321 tggtacacca aggtcaagag atgattggct cgtccattta ccagttccct tgttacctgc
    58381 agcatcaagg atgtagtcta cgattggtcc atcttggtct tcatcgtctt tacggctcaa
    58441 gatatcagct gtgatttcga tcaagtagct atccaattca cccttgttcc actcagtaaa
    58501 gatttcagcc atatcctctg cagaaaggcc tagcaagtgt tgcatcaagt catagctttc
    58561 tgcgatcaat tgcatatcac cgtactcgat accgttgtga accattttca catagtgacc
    58621 agctccatca ggaccgatat aagtcacaca tggtttgcca tcttctggtg ctttagctga
    58681 gatttcttca agaacatccg aaaccaattc gtaggcctct ttttgtccac caggcatgat
    58741 agaaggacct tcaagggcac ctttttcacc accagaaact ccagtaccga taaagttgat
    58801 acctgagttt gccaattctt cattacgacg gatggtatct ttgtagaaag tgtttcctcc
    58861 gtcaatcaag atatcacctt tgtcaaggtg tggaagaagg gcttggatag tagcatctgt
    58921 accaggtcca gcttgaacca tcagcatgat acgacgaggt ttttcgattg agtttacaaa
    58981 actttcaacg tcatagcttg gtacaaaatt cttttcagga tggcaagcaa tcacatcttc
    59041 cgttttttct ttactacggt tgtagatagc aactgtgtaa ccacgtgatt caatattaag
    59101 ggcaaggtta cgacccatta cggccatacc tacgacacca aagttagctt ttgtcatttg
    59161 acactcctct tgtttcattt gttttatttt atcattttta cttttgaaaa gaaagaattt
    59221 tgtaacgact gcttagtagt ccaagtcatc cgcatgacca gcgccatttc cgacaaagta
    59281 gcctgtctta cagttaaggg taaagagata ggttccatct ggcttataga ggttgtaata
    59341 accattgccg ttaacgatat tgacacgttc aaggatatat tggtctccag tgatatagcc
    59401 acgtgaacgt gaagttgcta gaatttgttc caaaacacca tccgcaaaat cccaggcaga
    59461 gttattacta tcatcaatag cagactgatt ataggcaaca cgactggcac ttctttgaac
    59521 agcaacccct gcactcgaga gacccatatt gacttcactg cgactacttc tagtctcatt
    59581 tgaactactt ggttttggct cactagtcgt atttgaactt gcttgacttg aacttgagct
    59641 gctagtttga cttgaacttg agctagaagt acttgtttgc tggctcttac caagactgat
    59701 agccttatct agcactttat caagctccgt atttccagtt ttaatatccg taaatttagc
    59761 atccgatttg gctttggcat tggtatccaa cacaccatcc acaatagctg gtttttcaaa
    59821 ttgtgcattg acatcttgaa tggccttgat ttgcgttact agactatcat atttagattt
    59881 ggcaagcgta tgttcacgac taccttccag cttatcaagt aaagtcttga gttgactcag
    59941 tttatcaaac tggctatttt tcaaagccgt tttattgcta tttgtgtaaa aggcgtcata
    60001 aagtgtatta aaatcatcca catccgattg attggctgta gttgattgag aagtttcaat
    60061 ttccttggtc gaacgagcca cttgacgata gacataataa gcactgacac aaataattac
    60121 tgatacaagc gccaaaacgg tcaaaataaa gcctttttta cttttctttt ctgagtcctc
    60181 ttgatccaga cgagaaaggt tttgctcctc ttccacttct tcagtcattt ctgttggatt
    60241 ttcatcatct agcaatagag gatccaagcc ttgctcctca tcgtccagag gcaagggtag
    60301 taagatgtct tcagaagatg gaacttcctc cgaagaagct tctgacttct ctacagcctc
    60361 acgcatctct tgaattaaat catccagact ctgagtttca acgaactcct cttttttgta
    60421 ttgacgagtc gcaaacttat ccgcctcaat ttcatctctg tgttgcttaa catacttgtc
    60481 caaaatggaa tcctcaggca agactcctgc ttccacttct tcatttttac gaatagcttg
    60541 accaactgtt agctcttttg cttcatcaaa atcaaattgc ggttcttgac cttctttttt
    60601 atgacgattt cgtctttttt tactcatgag tatccctttc tattttacct cttgccgttt
    60661 gacacgctga ccaaaatatt gatatagatc cactttcaag gttccgttgt ataacttacg
    60721 cttcttatct gcttggctac catacttgct ttcaaaagct tcatcactag tcaggataaa
    60781 tttgctccaa gttttcagcg gtgcaaatac ttgccccatc tcagcataga gcttggtcac
    60841 tcctgcatca tctgacaaac gttcaccata aggcggattg gaaatgatta ctccattgat
    60901 tttatcggaa cgtaaatcct gcacgcgcat ctgcttaaaa gtaatatctc ctgcaacacc
    60961 agctgcctga gcattggcct tagcaatttc caccatgcga gcatcaatat cacagcccat
    61021 gatatccaac tcaagcttac gttctacttt tttagccgct tctgtgcgca cttcttgaat
    61081 caagcgatcg ctgatccagt tccattcctc aaatgcaaaa gagcgacgaa gacctggcgc
    61141 catctttcta gcaatcataa ctgcctcaat acagaaagtc cccgaaccac aggtcggatc
    61201 aatcaaaggc ttgtctggat accagttaga aagttgtaaa atggctgctg ccatattttc
    61261 cttgatagga gcgccacctt tttcggtacg ataaccacgt ttaaagaggc tagacccggt
    61321 cgtatcaatc atgacagttg ccacatcttt gagaatagag acctcaatct taaactctgg
    61381 gccattctcc atcagaggaa ccccttctgg gcgagcatag tgtttctgca atttcttgac
    61441 aacagctttc ttagaaatag cctgaacact gggctcattg tgaagtttgg acttaacaca
    61501 tttagctttt gaaatcggta accgagctcc aagtggtaaa taattttccc aatctaaagc
    61561 gaaaactccc tgaaatagct cttcaaaagt cttagctggg aacgttccta cgataatttt
    61621 gatacgatct gctgcccgaa gccaaaggtt ggtttcgata atagctctca cgtctccttg
    61681 aaaacgaaca cgtccatttt caacctgaca atcgtagccc aactctcgca cttcacgacc
    61741 aacgacagcc tcaagccctg ctgccacagt tgcaattaaa ttaaattctt ttttcatgtt
    61801 acagtcttgc aagacctttc tatatgtcca ctttaaaaaa tgaggttgag aaaatttctc
    61861 agccccaacc tatatgcaat tttctataag ccatgttttg ttccagaagt gactaggacc
    61921 acttccttcg ataatcatct gtctaccact aacagctcta gctgatagca gtcagaatac
    61981 tacgttcgtt tccgcatact ccatgccccg accaaaattt gggttgctag cttgaggggt
    62041 ttaccgcgtt ccactctctc tgtttccaga aagactccgt cactgtggca ctttcaagcc
    62101 tactctggcc tatccaagga cttagccatt tcaactgccg taacgatttc tcgtccctag
    62161 gcttatggtt tcgcctagca caaacactac aggcatcaca gcctgtgcta gcatggactt
    62221 tcctcatgag aagcaattct cctcacgcga ttatccaaaa attgcacatc tcaaataact
    62281 acttaaaaat ctgagttatc taaaatttgt ttaccaaaaa cttctttttc caatctattc
    62341 aggcgtttca aaatatcaaa attcgtcata gaacttgtaa ttgccgcttc aaggggttct
    62401 gcttgaactg gtgaaggttt cggtttacga gttaattctt ccttcaaatc cgcaatttcc
    62461 tgacgaagtg acttgaccaa ggcagcatag gtttcatagt ccttgatgac atcgtctaaa
    62521 aactcgtcaa cttctacttt attatagcca cggacttcac gtccaaactc ttgttcaaaa
    62581 atatctttcg ctgaaaaaat aatacttgcc atgtctctct ccattctcgc ttgctagtat
    62641 tattatataa aaaaaggcaa acaaaaatca aggtcaaagc ttcaattttc ggaaaaattt
    62701 tcagcaagtt catttaattg atcaaatgtt aatctcttta taaaatagtc ctcttgattt
    62761 ttcatctttt ggtaaaaata agctagtttt gtttcatttt cttcatcata aaaaagatag
    62821 gaactagtcg tgttttccag caaaaactgc tggtaatctc ttaactgccc cttgtgttca
    62881 tagcgaggat aagcatattt gacaaagtct acctgcttaa agcgactcag tttcatctga
    62941 ttgccttcat tccaattttc cccatgggtt tcaaaagcaa aaatggtggc caactggaaa
    63001 ccgtattcgg ttttcatctc ctgagcaacc tctaaaaccc aatattcaaa acccaaactc
    63061 cctgtaaaca caagccaaga caccccatct gctgccatag cctctaaatc tttacgtatc
    63121 gcttttttaa tcaatttaag acgaggatcc ttatcagaaa ataaacccaa atcaaaagca
    63181 gaatagccta aaaccaaagc tgtagccatt tttaaccctt tctgtgcaaa ttatggtata
    63241 ataaagtgat gttattgtac caataaggag aattatgatc aactatccac ataaagtttc
    63301 atcacaaaaa agacaaacat ctctttctca acccaaaaat ttcgcaaatc gaggaatgtc
    63361 ttttgaaaag atgatcaatg ctaccaacga ctactatttg tctcagggct tggctgttat
    63421 acataagaaa ccaactccta ttcaaatcgt acaagtggac tatccacaac gaagtcgtgc
    63481 caagattgtt gaagcctatt ttcgacaagc ttcaacgacg gactattctg gcgtttataa
    63541 tggatattac atcgactttg aagtcaagga aacaaaacaa aaacgtgcga ttccgatgaa
    63601 aaattttcat ccacatcaga ttcagcatat ggaacaagtc cttgcccaac aaggaatctg
    63661 ctttgtcctt cttcactttt cttctcagca agaaacctac ttattgccgg cattcgattt
    63721 gattcgcttc tatcatcaag ataagggaca aaaatcaatg ccacttgaat atattcgaga
    63781 atatggatat gaaatcaagg ctggtgcctt ccctcaaatt ccttatctca atgttatcaa
    63841 agaacattta ttaggtggta aaacaagatg aacaaaccaa cgattctgcg cctaatcaag
    63901 tatctgagca ttagcttctt aagcttggtt atcgcagcca ttgtcttagg cggaggagtt
    63961 tttttctact acgttagcaa ggctcctagc ctatccgaga gtaaactagt tgcaacaact
    64021 tctagtaaaa tctacgacaa taaaaatcaa ctcattgctg acttgggttc tgaacgccgc
    64081 gtcaatgccc aagctaatga tattcccaca gatttggtta aagcaatcgt ttctatcgaa
    64141 gaccatcgct tcttcgacca cagggggatt gataccatcc gtatcctggg agctttcttg
    64201 cgcaatctgc aaagcaattc cctccaaggt ggatcaactc tcactcaaca gttgattaag
    64261 ttgacttact tttcaacttc gacttccgac cagactattt ctcgtaaggc tcaggaagct
    64321 tggttagcga ttcagttaga acaaaaagca accaagcaag aaatcttgac ctactatata
    64381 aataaggtct acatgtctaa tgggaactat ggaatgcaga cagcagctca aaactactat
    64441 ggtaaagacc tcaataattt aagtttacct cagttagcct tgctggctgg aatgcctcag
    64501 gcaccaaacc aatatgaccc ctattcacat ccagaagcag cccaagaccg ccgaaacttg
    64561 gtcttatctg aaatgaaaaa tcaaggctac atctctgctg aacagtatga gaaagcagtc
    64621 aatacaccaa ttactgatgg actacaaagt ctcaaatcag caagtaatta ccctgcttac
    64681 atggataatt acctcaagga agtcatcaat caagttgaag aagaaacagg ctataacctg
    64741 ctcacaactg ggatggatgt ctacacaaat gtagaccaag aagctcaaaa acatctgtgg
    64801 gatatttaca atacagacga atacgttgcc tatccagacg atgaattgca agtcgcttct
    64861 accattgttg atgtttctaa cggtaaagtc attgcccagc taggagcacg ccatcagtca
    64921 agtaatgttt ccttcggaat taaccaagca gtagaaacaa accgcgactg gggatcaact
    64981 atgaaaccga tcacagacta tgctcctgcc ttggagtacg gtatctacga ttcaactgct
    65041 actatcgttc acgatgagcc ctataactac cctgggacaa atacccctgt ttataactgg
    65101 gataggggct actttggcaa catcaccttg caatacgccc tgcaacaatc gcgaaacgtc
    65161 ccagccgtgg aaactctaaa caaggtcgga ctcaaccgcg ccaagacttt cctaaatggt
    65221 ctcggaatcg actacccaag tattcactac tcaaatgcca tttcaagtaa cacaaccgaa
    65281 tcagacaaaa aatatggagc aagtagtgaa aagatggctg ctgcttacgc tgcctttgca
    65341 aatggtggaa cttactataa accaatgtat atccataaag tcgtctttag tgatgggagt
    65401 gaaaaagagt tctctaatgt cggaactcgt gccatgaagg aaacgacagc ctatatgatg
    65461 accgacatga tgaaaacagt cttgacttat ggaactggac gaaatgccta tcttgcttgg
    65521 ctccctcagg ctggtaaaac aggaacctct aactatacag acgaggaaat tgaaaaccac
    65581 atcaagacct ctcaatttgt agcacctgat gaactatttg ctggctatac gcgtaaatat
    65641 tcaatggctg tatggacagg ctattctaac cgtctgacac cacttgtagg caatggcctt
    65701 acggtcgctg ccaaagttta ccgctctatg atgacctacc tgtctgaagg aagcaatcca
    65761 gaggattgga atataccaga ggggctctac agaaatggag aattcgtatt taaaaatggt
    65821 gctcgttcta cgtggagctc acctgctcca caacaacccc catcaactga aagttcaagc
    65881 tcatcatcag atagttcaac ttcacagtct agctcaacca ctccaagcac aaataatagt
    65941 acgactacca atcctaacaa taatacgcaa caatcaaata caacccctga tcaacaaaat
    66001 cagaatcctc aaccagcaca accataacat ttatcaccca gatttttctg ggtgattttg
    66061 tcatagcact attgtattta tgtgcttaac aaaagcctga gaagatgtct tctcaggctt
    66121 tttctgtact ataaacctca ttggaaaaga tagagactgc ttccgtaatc ttgttaagag
    66181 gttttactaa atactagtct ttcttcgttt ttactacaaa gagagcagat agggctagac
    66241 taacacttgc taggaagagg gctgtgtcag attgactctc acctgttgct ggcaagattt
    66301 gttcaggtgt ttctggtcta gctatttctt gcttataatc tggcgtctta ccttgatcgg
    66361 aaactaaaga gctaagttta aactcaggtt tctctacagt tggagcatct ggtttcgtag
    66421 cagaatcttt taattggttg agataatctg caaagtattc caccattctt tccgtcaaga
    66481 gatggttatc cgtcgcatat ttcatgcttg cctgaacgct agctacttcc tcttgattgt
    66541 ctttgtctgt taatttctga gctttagcca aagctgcttc atagcctgac aagtcaagag
    66601 gtgtttctgc tacctgtgga cgagtaaaga tgagttccgc tgcagattgg tatttatcgc
    66661 caccatctcc gtaagtctta gtacctgtaa ggacaatttt cttagcctta attgtcttac
    66721 caaaatcaat gtcttttggc ttattgttat ctggccaatc agttgcagta aaggtatgct
    66781 ccttgccaga ctcatctgtc acaacaagtt tcacatcacg caagttacca tttgaacctg
    66841 atccacgtgg aacgtaacga agtccagtga tttcagttgg ttctttcaag accatggttg
    66901 caggcttgcc tacatctcca ccattccaag atgtatgcca taaactagat aagtttccat
    66961 caaaggcatt tgcaagacct tcttgagcct gagcaggagc tgtaagactt gcaaagtcat
    67021 ctgctaccaa agccgttttc ttctgaacca aagcattctt caaggcttca atcttggcaa
    67081 tctctgcacg cgcttcttcc acactgatat catcatcggc ctgactaagg ttaaagaccg
    67141 cctctttcaa agcatccata gactctttgg tgtagttagt catggcaacc gttggcaagt
    67201 agttcttcag agcattttct gtcaacatct tacctgttag ggtaatttct tcgatttgaa
    67261 gattatccat catgaagtcg ttataaccac ggaagttggc atttccacca gaatcaccac
    67321 gagtattact tgcattgcca gttgagtaga tacctaccca agtatcccct gtttctgcac
    67381 ctgtcacaag gaaggttgcc ttcttggctt tcttagaatc tgtccaagta tttggcaatt
    67441 catgcatttc caagttgctt gcttgagtgc cacgacgacc tgactggaat tctcccttac
    67501 cgactacaaa agcataggta ttgtctgaac ctgcttcgta ttcaaaggtt acacggtagg
    67561 tcttacctgc ttcaaaacgg aagttttgtg ggatggtttg gtaaaccaag ttacgacggc
    67621 tcactagtcc atttgtcttg agtgaccaat ttccttcgat aacatcatcg actttcttac
    67681 cgttccaacc acgttgtgta tatggatcgt gtttttcaga caagtgagtg cggttgtctt
    67741 cgacaccttc gacaccaccc actacaaatg ggaagattcc ttgagctaca ttttcaaagt
    67801 cttgcttgaa ggttccttga cctgtatcgt gcttgtctcc atacatgctt gaattgtttt
    67861 caaaggtacg aatttcatca aagtaagttg cttgatcacc agcttcacga ctcaatgtca
    67921 gagtaacatt tgagacgtcc gatcctgttg taaagaaggc gtacatgttt tggaagtaac
    67981 ttgtatcgtt aactgtagca ttgttacgac gtgtattgtg ggcgtaggct tttacatagt
    68041 tgagggcgag agacttattg gtataagtag tcacttcttt ttcaccagta ttcacagtga
    68101 tacttgcctt ggcattacta cggttatcga caccgacata aacggcatac ttggtatttg
    68161 gtttcaagcc agttaatttc tgagtgagac taactttttc tttgtttcct tgaatacgaa
    68221 gcatatcgtt tgccccttga gacttgacaa tttctgcctt agaagcatcg cctgaaatgg
    68281 tccaatgttt caaggtacca ctgttaaatc cttggtcata gatgtgcatg ccttcactcc
    68341 atgacatttc aggattggtt tgttttgaac gatagagaac gtatggttga tttgctagaa
    68401 gatctagggt aattttacca tcttttacag ttagttcttg ctcttctgtc ttaccttggt
    68461 cagttagctt gtaaaggtaa accttgctct ttgcccaatc gcttggaagg gtccaagttg
    68521 ttgcaccggc ctgcgtattg aagtagtaca tcttttcctt atcagtagaa agtttcttac
    68581 catttgcatc ccagttccaa ggagtcaagt aagctgaacc atcttggatg acacgtccgt
    68641 tgagagttac tgtacgttcg cgatattgtg gactattgac atcatttgac ttacgagtta
    68701 caactacttt attattgtca gcatctacca attccactcg catttctgga gtccatttat
    68761 aggtactacc gttatcggtc atagtcaccg gtgtaccatt ttcccattta cttacagtga
    68821 agtgttggaa gtacttagtc atgacgtcat gggcaaataa gttggttaca tagccattgt
    68881 agtcacttct tccctgccag ccttcaaagt ctttcatgct gtagccacct agcagtggat
    68941 agttggctgc accaccataa cttctgtagt ccccaaccca agcatctttt tggtggttac
    69001 ggataaagcg ggtgatggca ctgttgatac ctttattggt gtagccaccg taggtcaagt
    69061 cagctgccca gtgatggaag gtagagtcgt actcaccacc atggccccac tcgatcgcaa
    69121 agcgccagcc ttgtttgtta atttctttag caagaacgtg ggtagcccag gcaccgttat
    69181 cacctgattg accattaccc caaacgtcca catagataaa gtcgagaccg tcaccaagtt
    69241 ttttcttcaa atcttcccaa cgtgccaaac gaccatgagc taggtcatag gcagcatcaa
    69301 tgttgatacc ttgatctagc cagttccaac catagctata gcttccatct ggattcttac
    69361 ggagaatttt ttcattgaag tatttagact caggataagt ttctgaagcg ttaacgtgga
    69421 tacctagatg agctccatat ttcttagcct tctcaattag ggtcttgaag tcttcgacac
    69481 caccgatacg cttaccaata tcagcatagt tcaagtgacc agagtcatgg ccttcgctac
    69541 catatccttt aaggaaaaca ccttgcccaa gaccatctgt gtggagattg attttcttga
    69601 taccatccaa ggtcataagg aatggatttt gtgcttgaga accaaagttc atcgcgatac
    69661 ggtaagctgt gatatcctta actttttccc aaccttgagg attgttcata atgctacgat
    69721 aagcaatggc accatcttgc caatcgactt tcttgtctgc attggcatct tcagtgataa
    69781 caaccttagc acttggaagt tccttcgtgt attctgggaa aacaatgccc ttataagctt
    69841 tttcccattg ccattcagag ctgtggattc ctacatagtt ggcatttccg actgtttctt
    69901 tataagctgt caaacgagtc cagtcattcg aaccaccacc atagctattt tgagagttac
    69961 tccaaacacc agcagcaagc ttatctgtag aaacaaatcc atacatgtaa cccttggcta
    70021 ggtctttcat tggattggtt acatcgatat gatcatctcc gctgacatgc gtattgtttg
    70081 acatggttgc cccatcaaac ttagcaccag tttgatcact agaaacagag actaaagcat
    70141 tgccgaggaa actaatagaa gaaagtagtt ttctttcgtc atcaatcttt tgacctggag
    70201 tgacttgatt gtggttgaca atcttggtca catcaaagtg caattgattg tccacaactt
    70261 gcaagcgtac tgtcatttcc gcattgatta agtgagcatc atcgcgaagc ttcatcaagt
    70321 actctgctgt tgtctcattg attttcttat aagtgacttc aggggtgatt cggtggttat
    70381 tgataaagac ttggttgaac tgttgcacct gtcctggcaa agtatgtcca ttcaagctgt
    70441 attccttgac acgagggaag gcttggtcaa tcactgcttt gaggacctta gactggatcg
    70501 tatcataagt caccttgcta tcgtcaacaa ccggacctgt ttctttctgg gcaggagtat
    70561 catccgcttt tacgccttct tgattgtctg ttttaacgct gacaactgta cggtcattgc
    70621 cataagttcc tgccttgaga aggatcttct tctcattttt aagattatca ttgaccgccc
    70681 caggcagtgt cactgtgtca aagagattga catcgttatt gctggcattg agttgtccat
    70741 ctgacttgag agtgatagaa agacggttta cagaacccgg ttctggtgca actacacggt
    70801 tgcctttata ccatgtgcta ttacctggag ttttgtattc ccagaaccag ccatccttgt
    70861 cataaccgac aaaaacatta ttattggtat ctttaaattt caggaagaca ccaaagcgtg
    70921 atttgccctt ttcagaatct tctttgaagg ttaaatcaac agttgcattt ccattggcat
    70981 caacggtcaa gcccttcttt tcaaacaggg ctggtttgcc tgcgttatca ttttgagcag
    71041 ttgagaatag ttggttgtag cggacacctt tttcttctcg gatagtgact gttccctgtt
    71101 gttctttttt ctctaccgtt tgccattcag gagttaccgt cttaggtgtt tcaggtttag
    71161 cagctgcagg tttatcctct tttggttttt cttcagccgg tttttctttt tcaagtgcta
    71221 atagttcttc ttctgtctta ggtccatctg taacttctgg agaaccttgg tcttctccca
    71281 ccttaggcgc ttcaaaatca cgcccatcat tctcgtttgc tgttgcaaga gcagtagcta
    71341 aatcagctgg taagttcgcc gtggaaccag actgcacgct atctgcaaga accggacttg
    71401 tcccaaagaa tgcagctcca atcataacag aagcaacacc taatgaaaat ttccgaatac
    71461 tatatttaca acgtttttca aataatcctt tattcataaa cttctaaatc ctttcatttt
    71521 ttagcaagcg tttacatttc ctttttaaaa aatactcctt cctctgaaag tgcaatgctt
    71581 aaccctgata aataaaaaat aattgtactt ttaatataac aaataatagc tgagaaagca
    71641 ataggaaaca agtaaaatta acaaaaattt tctctattct gacaaaaaga ggctccaact
    71701 tttgggggtc agtacattta gaatctttct ttacaaatgt aaaaaaggat tcagcattca
    71761 agagaaatac taaatccttt cttatatttt gcaacagtta tttcacatgt tttgcgagat
    71821 cttcttgagc ctttttatta gactcttctt tttctttcat ccatttttcc tgagcttttt
    71881 ggtattcatc tacagtgact gccttgtctt gaagttccaa gtatttatac aagactggtt
    71941 cacttgtacc tttatttcct gacaatgcaa atggtattgt aaatggtacc atcttagaca
    72001 agattgggcg ccctgtacga gatgtagttg gaataatcaa agcactatct gtcaaccaag
    72061 cttgggctgc agcgtattta tcatagcgtt tagcaacatc tgtagcctca tcaccagcct
    72121 cagtgaccaa tttttcgtag tcatatagac ctactttttt agcagctaca ttatcttccc
    72181 ctgagtcaaa ccctaaatat gttttagtac tttctcctac agaaggtttg ataatatcaa
    72241 ggtaggttga tggatcggca aagtctggac cccaaccgac attatctgat aaatcccagt
    72301 cttcgccagc agcattttca gcaaaatatg taatattgtt tacttcgtct ttttgtagtt
    72361 gttggatatc aataatgaca ttatcagctc ctaaagttgc ttccaaggat tgtttcatag
    72421 attggacgcg ctgaactttt gtagttgctg tctggtcaac tggcatatcc aaatgaattg
    72481 ggaaagtcac accttctgct tgtaaggctg atttagcttt agcaaattca gccttggctt
    72541 tttctggatt gtaaagacca tcctgagaat ctgcaagatt aacatccttc cattcatccc
    72601 cataagtgac caatttctct ttgaccatat cgccaaagtt tttaccatct gcttgaacaa
    72661 atgttggtgg aacaaagata ttacgtaaga ttttgcttgc tccagtttgt ccattcaact
    72721 gagaggcata ggctgtacga tcaaaaccaa aggcaatagc ctgacggaaa tccttgttta
    72781 agagagcctt tttagtcgat gccttttgtt cgtcgctggt cttagatgta tatttatagg
    72841 actgacggtc aatatttgta ccaactagat acgtaataga gccttgttga gtatagacaa
    72901 tattgtcctt catactcttc tcaagctctg cgaaacttgc acttgttgga tagagacgag
    72961 ctgctgtaag gctaccatct ttaaagtttt ctgcaggttt gctggtatct tgaccatccc
    73021 agaatgacaa tttaactttg tcaacatgca cattgtcctt atcccagtag ttcggatttt
    73081 tcgcaaattc aacagaggat tttgtcacaa tggatttcaa caaataagga ccgttataca
    73141 agagactact tggatccgtc gctttggcaa aatcatcccc ttttgagttc aaaaactctt
    73201 cattaactgg cgcaagcaca cccatggttg tcttagaatt ccagaagctt tctggtttgt
    73261 tcaaagtgta ctgaactgtc tgatcatcca aagccttaat tcctacttgt gagaaatctt
    73321 tgatttcccc ttttacatag gcatccaacc ctttgattga ttcttgaaca aggtaaagag
    73381 catctgattt tttatcagca gcatatttta gtcctgttac aaagtcttga gctttgactg
    73441 ccgcgtattc ttcaccttca gaagtatacc attttgcatc cttacggata gtataagtgt
    73501 aagtcaatcc atccttggat acagaccaat cctcagccat agacggcaca aagttcccgt
    73561 agcgatcatt ttctagcaaa ccatcaacca cgttactggt aatatttgct gtcgcagcct
    73621 tagcagttgt caaatagttg aggttatcag ggtctgtctc ataaatgtat gagaatgtct
    73681 tctcaccttt agtgcttgaa cctgatccag agcatgcagc taaagtagtc gccgccaata
    73741 atgtcacgcc cgcaagggca agtagttttg aacttttcat ccttttctcc tttaaaactt
    73801 tctctccatt atagactctt ttcagaaagt tgtcaacaga attttcagaa tttttgaaaa
    73861 ttatttttca aataacatct ttgcaaaaaa tatgaatatc gtaaccgccc aataacgaag
    73921 tctattgaaa aatctccaga ctagagaact cacggatagt tcctaatctg gagatttctt
    73981 atttgcactt ttcttgtaca actttagtcc acggtaaata ggcctctaaa atctctttgt
    74041 ttacgagagt ttcctcgttt ggaagacatt ctagaagata ggatagatat ttctcgctat
    74101 ttaat
//
LOCUS       DAVAZT010000002        67528 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVAZT010000002 DAVAZT010000000
VERSION     DAVAZT010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 67528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67528
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.002"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(134..1882)
                     /locus_tag="VQT45_000076"
     CDS             complement(134..1882)
                     /locus_tag="VQT45_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2358486.1"
                     /translation="MKRQTVNQTLKRLVVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKELSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTISRVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            complement(1884..3608)
                     /locus_tag="VQT45_000077"
     CDS             complement(1884..3608)
                     /locus_tag="VQT45_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2358487.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFLSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGLNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENLPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            complement(3666..4604)
                     /gene="msrB"
                     /locus_tag="VQT45_000078"
     CDS             complement(3666..4604)
                     /gene="msrB"
                     /locus_tag="VQT45_000078"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET2358488.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            complement(4746..4823)
                     /locus_tag="VQT45_000079"
                     /pseudo
     CDS             complement(4746..4823)
                     /locus_tag="VQT45_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(4899..5768)
                     /locus_tag="VQT45_000080"
     CDS             complement(4899..5768)
                     /locus_tag="VQT45_000080"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HET2358489.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTKGVRVEAK"
     gene            complement(5770..7056)
                     /locus_tag="VQT45_000081"
     CDS             complement(5770..7056)
                     /locus_tag="VQT45_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HET2358490.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(7207..7944)
                     /gene="mecA"
                     /locus_tag="VQT45_000082"
     CDS             complement(7207..7944)
                     /gene="mecA"
                     /locus_tag="VQT45_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HET2358491.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(8144..9178)
                     /locus_tag="VQT45_000083"
     CDS             complement(8144..9178)
                     /locus_tag="VQT45_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET2358492.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(9207..10640)
                     /locus_tag="VQT45_000084"
     CDS             complement(9207..10640)
                     /locus_tag="VQT45_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HET2358493.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFIAKMLTKEN"
     gene            complement(10656..11642)
                     /locus_tag="VQT45_000085"
     CDS             complement(10656..11642)
                     /locus_tag="VQT45_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2358494.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQIYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(11644..12747)
                     /locus_tag="VQT45_000086"
     CDS             complement(11644..12747)
                     /locus_tag="VQT45_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HET2358495.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDLEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQIIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(12737..13582)
                     /locus_tag="VQT45_000087"
     CDS             complement(12737..13582)
                     /locus_tag="VQT45_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET2358496.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLTLDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(13861..15135)
                     /gene="psr"
                     /locus_tag="VQT45_000088"
     CDS             complement(13861..15135)
                     /gene="psr"
                     /locus_tag="VQT45_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HET2358497.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(15132..15980)
                     /gene="pheA"
                     /locus_tag="VQT45_000089"
     CDS             complement(15132..15980)
                     /gene="pheA"
                     /locus_tag="VQT45_000089"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET2358498.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYIDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(15977..16453)
                     /locus_tag="VQT45_000090"
     CDS             complement(15977..16453)
                     /locus_tag="VQT45_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HET2358499.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRHVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(16446..17729)
                     /gene="aroA"
                     /locus_tag="VQT45_000091"
     CDS             complement(16446..17729)
                     /gene="aroA"
                     /locus_tag="VQT45_000091"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HET2358500.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(17821..18159)
                     /locus_tag="VQT45_000092"
     CDS             complement(17821..18159)
                     /locus_tag="VQT45_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HET2358501.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(18170..19273)
                     /locus_tag="VQT45_000093"
     CDS             complement(18170..19273)
                     /locus_tag="VQT45_000093"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HET2358502.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            complement(19283..20449)
                     /gene="aroC"
                     /locus_tag="VQT45_000094"
     CDS             complement(19283..20449)
                     /gene="aroC"
                     /locus_tag="VQT45_000094"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HET2358503.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(20459..21526)
                     /locus_tag="VQT45_000095"
     CDS             complement(20459..21526)
                     /locus_tag="VQT45_000095"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HET2358504.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWKVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            complement(21545..22399)
                     /locus_tag="VQT45_000096"
     CDS             complement(21545..22399)
                     /locus_tag="VQT45_000096"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HET2358505.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKKMPTEEIW
                     QSLTEKYQ"
     gene            complement(22389..23066)
                     /locus_tag="VQT45_000097"
     CDS             complement(22389..23066)
                     /locus_tag="VQT45_000097"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HET2358506.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(23063..24226)
                     /locus_tag="VQT45_000098"
     CDS             complement(23063..24226)
                     /locus_tag="VQT45_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HET2358507.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQAFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDERRFIVMDVFEYF
                     KYAKRKNLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(24911..26545)
                     /locus_tag="VQT45_000099"
                     /pseudo
     CDS             complement(24911..26545)
                     /locus_tag="VQT45_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(26526..27275)
                     /locus_tag="VQT45_000100"
     CDS             complement(26526..27275)
                     /locus_tag="VQT45_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2358508.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSAPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVEN
                     LRKDHPDQFLESIYLSLAGRKEEVADASQGH"
     gene            27454..28908
                     /locus_tag="VQT45_000101"
     CDS             27454..28908
                     /locus_tag="VQT45_000101"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HET2358509.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKEQGIQPMADVVL
                     NHKAAADNREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(28998..31616)
                     /gene="alaS"
                     /locus_tag="VQT45_000102"
     CDS             complement(28998..31616)
                     /gene="alaS"
                     /locus_tag="VQT45_000102"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HET2358510.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLISPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNTSQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKIVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(31638..32123)
                     /locus_tag="VQT45_000103"
     CDS             complement(31638..32123)
                     /locus_tag="VQT45_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HET2358511.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLLDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(32398..32637)
                     /locus_tag="VQT45_000104"
     CDS             complement(32398..32637)
                     /locus_tag="VQT45_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2358512.1"
                     /translation="MKMSTFFNKSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILEK"
     gene            complement(32890..33960)
                     /locus_tag="VQT45_000105"
     CDS             complement(32890..33960)
                     /locus_tag="VQT45_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2358513.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDS
                     AYAFINFMLKPENALQNAEYVGYSTPNIPAKELLPEETKEDKAFYPDVETMKHLEIYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(33957..34730)
                     /locus_tag="VQT45_000106"
     CDS             complement(33957..34730)
                     /locus_tag="VQT45_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2358514.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(34727..35533)
                     /locus_tag="VQT45_000107"
     CDS             complement(34727..35533)
                     /locus_tag="VQT45_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2358515.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(35514..36671)
                     /locus_tag="VQT45_000108"
     CDS             complement(35514..36671)
                     /locus_tag="VQT45_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2358516.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(36730..37680)
                     /gene="murB"
                     /locus_tag="VQT45_000109"
     CDS             complement(36730..37680)
                     /gene="murB"
                     /locus_tag="VQT45_000109"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HET2358517.1"
                     /translation="MSVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            complement(37792..38544)
                     /locus_tag="VQT45_000110"
     CDS             complement(37792..38544)
                     /locus_tag="VQT45_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HET2358518.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWFEKKR
                     SLEKADALAYGLGHGGLELIFLGLTSLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLTAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(38554..39285)
                     /gene="budA"
                     /locus_tag="VQT45_000111"
     CDS             complement(38554..39285)
                     /gene="budA"
                     /locus_tag="VQT45_000111"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HET2358519.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFLHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            39427..40698
                     /locus_tag="VQT45_000112"
     CDS             39427..40698
                     /locus_tag="VQT45_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HET2358520.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(40718..41533)
                     /locus_tag="VQT45_000113"
     CDS             complement(40718..41533)
                     /locus_tag="VQT45_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET2358521.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEILSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKIDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(41690..42343)
                     /gene="phoU"
                     /locus_tag="VQT45_000114"
     CDS             complement(41690..42343)
                     /gene="phoU"
                     /locus_tag="VQT45_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET2358522.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(42355..43113)
                     /gene="pstB"
                     /locus_tag="VQT45_000115"
     CDS             complement(42355..43113)
                     /gene="pstB"
                     /locus_tag="VQT45_000115"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET2358523.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(43126..43929)
                     /gene="pstB"
                     /locus_tag="VQT45_000116"
     CDS             complement(43126..43929)
                     /gene="pstB"
                     /locus_tag="VQT45_000116"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET2358524.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(43940..44824)
                     /gene="pstA"
                     /locus_tag="VQT45_000117"
     CDS             complement(43940..44824)
                     /gene="pstA"
                     /locus_tag="VQT45_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET2358525.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(44814..45731)
                     /gene="pstC"
                     /locus_tag="VQT45_000118"
     CDS             complement(44814..45731)
                     /gene="pstC"
                     /locus_tag="VQT45_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET2358526.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(45731..46609)
                     /gene="pstS"
                     /locus_tag="VQT45_000119"
     CDS             complement(45731..46609)
                     /gene="pstS"
                     /locus_tag="VQT45_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HET2358527.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(47183..48487)
                     /locus_tag="VQT45_000120"
     CDS             complement(47183..48487)
                     /locus_tag="VQT45_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HET2358528.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEEFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(48488..49261)
                     /locus_tag="VQT45_000121"
     CDS             complement(48488..49261)
                     /locus_tag="VQT45_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HET2358529.1"
                     /translation="MKSKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLASFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(49251..49529)
                     /locus_tag="VQT45_000122"
     CDS             complement(49251..49529)
                     /locus_tag="VQT45_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HET2358530.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGKGKISLEK"
     gene            complement(49529..49930)
                     /locus_tag="VQT45_000123"
     CDS             complement(49529..49930)
                     /locus_tag="VQT45_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HET2358531.1"
                     /translation="MITLFLSPSCTSCRKAKTWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(50140..50757)
                     /locus_tag="VQT45_000124"
     CDS             complement(50140..50757)
                     /locus_tag="VQT45_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HET2358532.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(50747..51520)
                     /locus_tag="VQT45_000125"
     CDS             complement(50747..51520)
                     /locus_tag="VQT45_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HET2358533.1"
                     /translation="MKYKGYLIDLDGTIYKGKDQIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKEKPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(51531..52268)
                     /locus_tag="VQT45_000126"
     CDS             complement(51531..52268)
                     /locus_tag="VQT45_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HET2358534.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIVEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEESISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(52273..53403)
                     /locus_tag="VQT45_000127"
     CDS             complement(52273..53403)
                     /locus_tag="VQT45_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HET2358535.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(53487..53876)
                     /locus_tag="VQT45_000128"
     CDS             complement(53487..53876)
                     /locus_tag="VQT45_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET2358536.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(53892..54275)
                     /locus_tag="VQT45_000129"
     CDS             complement(53892..54275)
                     /locus_tag="VQT45_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HET2358537.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(54276..55064)
                     /locus_tag="VQT45_000130"
     CDS             complement(54276..55064)
                     /locus_tag="VQT45_000130"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HET2358538.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(55057..55992)
                     /locus_tag="VQT45_000131"
     CDS             complement(55057..55992)
                     /locus_tag="VQT45_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HET2358539.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLSETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(56122..56298)
                     /locus_tag="VQT45_000132"
     CDS             complement(56122..56298)
                     /locus_tag="VQT45_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HET2358540.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(56438..57145)
                     /locus_tag="VQT45_000133"
     CDS             complement(56438..57145)
                     /locus_tag="VQT45_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HET2358541.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            57296..58324
                     /gene="queA"
                     /locus_tag="VQT45_000134"
     CDS             57296..58324
                     /gene="queA"
                     /locus_tag="VQT45_000134"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HET2358542.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIINMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDSMFIY"
     gene            complement(58995..59384)
                     /locus_tag="VQT45_000135"
     CDS             complement(58995..59384)
                     /locus_tag="VQT45_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET2358543.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(59438..60145)
                     /locus_tag="VQT45_000136"
     CDS             complement(59438..60145)
                     /locus_tag="VQT45_000136"
                     /inference="COORDINATES: protein motif:HMM:NF019142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET2358544.1"
                     /translation="MFRRNLNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGGIIVK
                     VATKPKVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGHVTE
                     QVTVDRKQATDTVIKVPAKSKVEEVLVPCATKYEADNDLSAGQEQEITLGKNGKTVTT
                     ITYDVDGKSGQVTESTLSQKEDSQTRVVKKGTKPQVLVQEIPIETEYLDDPTLDKSQE
                     VEEVGEIGKLLLLQSIL"
     gene            complement(60845..61396)
                     /locus_tag="VQT45_000137"
     CDS             complement(60845..61396)
                     /locus_tag="VQT45_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2358545.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDIEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(61794..62618)
                     /gene="nadE"
                     /locus_tag="VQT45_000138"
     CDS             complement(61794..62618)
                     /gene="nadE"
                     /locus_tag="VQT45_000138"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HET2358546.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(62615..64075)
                     /locus_tag="VQT45_000139"
     CDS             complement(62615..64075)
                     /locus_tag="VQT45_000139"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HET2358547.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(64191..64679)
                     /locus_tag="VQT45_000140"
     CDS             complement(64191..64679)
                     /locus_tag="VQT45_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2358548.1"
                     /translation="MKNRFYYYQLLDEREEQLINKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(64669..64878)
                     /locus_tag="VQT45_000141"
     CDS             complement(64669..64878)
                     /locus_tag="VQT45_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2358549.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(65268..65710)
                     /locus_tag="VQT45_000142"
                     /pseudo
     CDS             complement(65268..65710)
                     /locus_tag="VQT45_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000640911.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(66002..66808)
                     /locus_tag="VQT45_000143"
     CDS             complement(66002..66808)
                     /locus_tag="VQT45_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2358550.1"
                     /translation="MILKDINFALNKGEIVGLVGRNGVGKSTLMKILVQNNQPTSGNI
                     ISSDNVGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQERFRSLIQELDLTQSINKKV
                     KTYSLGTKQKLALLLTLVTEPDILILDEPTNGLDIESSQIVLAVLKKLALNENVGILI
                     SSHKLEDIEEICERVLFLENGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGD
                     IVQEEGLRITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIYLNRSK"
     gene            complement(67214..>67528)
                     /locus_tag="VQT45_000144"
     CDS             complement(67214..>67528)
                     /locus_tag="VQT45_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HET2358551.1"
                     /translation="PEYKFVAEVVSYDDAAQTATIRQRNVINEGDQVEFYGPGFRHFE
                     TYIEDLHDAKGNKIDRAPNPMELLTIKVPQPVQSGDMVRALKEGLINLYKEDGTSVTV
                     RA"
BASE COUNT        20111 a        15200 c        12562 g        19655 t
ORIGIN      
        1 acctacggct agcttcctag tttgctcttt gattttcatt gagtattaca gtaaacaatt
       61 tttctagcta ttgtaacaaa aaagtcactc gaaggcaact tttttcgtcc ataaactttc
      121 aaaagagaat ggcttattca gaactaaaag ccgcagcttt ttgcatttgg taatacttac
      181 cctttctatc catgagttct tgatggttac catattcaac aatatcacca tctactaaga
      241 caagaattaa atccgcatcc tgaatggttg acaaacggtg agcaatgatg aagcttgtgc
      301 ggcccttcat gagttttgca aaggcatcct gtaccagcac ttctgtccgt gtatcaatgg
      361 aagaagttgc ctcgtctaag ataagaatct ttggaatagc cagaaagact cgggatatgg
      421 tcaagagctg agcttggccg acagagagag attctccagc attttccaac ttggtatcgt
      481 atccctgtgg caactgttgg atgaaaaagt ctgcattagc tgctttggca gcagcaatta
      541 cttgctctcg actggcttca ggattgccaa aggcaatatt atcatgaatg gtcccttgtg
      601 tgagccaggt ttcttgaagc accataccaa actgctgtct caatgatact cgtgtataat
      661 cataaatgga ttgcccatcc agcaagatat ctcccgagct aatgggataa aaacgcataa
      721 ggagattgat aagagttgat tttccagcac ctgtcggacc aacgatggct accttactac
      781 cagctggaat atcgatagac aactccttaa tcaaaatttt ttcaggatgg tagccaaaag
      841 agacatgttt aaaggaaata gctcccttaa cttggtcact ggtcaagact tccttacctg
      901 tttcagccac ttcagggcta tctaagaccc catagatacg ctctacgcaa gccagagcac
      961 tttgcaactc agctagcact gaagaaatat cgttaaaggg cttggtgtat tgctgaacat
     1021 agttcaaaaa agtcactaaa cgaccgacgg tcaaggttga acccatcatg atacgataag
     1081 ctcctactcc agctaaaagg gcataaatga gtgcatttac aaagcgagtc gaaggattga
     1141 ccgttgaaga ataaaagatg gctgactgag aatagcctga gtagttgtca tgagcctcac
     1201 gcaatctttg gataaattct gtttgagcat tgaaggactg gattatagtc tgctggctaa
     1261 gcgattcttc aatcaactga gtctgaattc ccctcgtctc tgtttgcttc tggaagagat
     1321 gataggatct cttggcaata aagcgtgaaa tcaccatgga cagtggcgtc aacagcaaga
     1381 ctaagagagt catgaggaga tgaatttgga gcatggctag aatactaacc aaaatcatca
     1441 aaacaccaat gaaaaattgg ttaaaaatca tggtcaagcc agctgccaac tgttcgatat
     1501 ccgtggttac acgactgacc atctctccat tgccttgccg atccgcaaaa gcaatcggta
     1561 accgatggag tttatggatg attcgctctc gtaaatctct ggtataagag aagattagac
     1621 gattatagag gagaggattg gcccattgta ccagagtatt tcctattacc accaagagca
     1681 tctggagaaa aatctgccaa aaaactggtg atgaaccagc cactaggact tggtcaatga
     1741 cctgcccaat cagaataggt aggtaaattg ataagccaac ttgggcaata gttcctagaa
     1801 aggctaggaa aaggaggaag ggatggtttg ctaaatctac gactaaacgt ttgagcgtct
     1861 ggtttacagt ttgtcgtttc attctagtcc tcctttccat gttgggatgc attgatttca
     1921 cgatagactt gactggattt catcaagtca tcgtgcttgc caacagctag caactcacct
     1981 ttttccaaga ggagaatctg gtccgccatc tggagtgtcg aagtccgttg agaaatcaag
     2041 attaagctca tatttggcag attttcgcgg atagctttca agagcttgga ctctgtaatg
     2101 gtgtccagtg ctgaggtcgc atcatctagg atgagaaacg gagcctggcg caagactgct
     2161 cgtgcgatag acagcctttg tttttgtcca cctgagaaat ttcgccctcc tgcttcaact
     2221 agagcatcca agagtccttc cttatcactg acaaaatcct tagcttgcgc aatctccaag
     2281 gcttgccaga gttcttgatc agtcacttct tgatttaaac ctaaagtcaa gttggaacga
     2341 atagttccct taaagagttc gaccttttga ggtacatagg caatccaaga ccgccactgc
     2401 tccaaattaa gaggactacg tccattttga taaaggtcaa tgttcccctt gtctactgga
     2461 taaagtccaa gtaagagttg caccaagctt gatttaccag aaccagtccc cccaatgata
     2521 ccaaggattt gtccttgagt catatcaaag gaaatgtctc tcagagaagg ctgggccgca
     2581 tcaggatagg taaaagtcaa ttcttggact tgtaaaaccc gaccactggt aacttgcttt
     2641 tgttctaatt ctgaatggat gttttcggga gattccgcaa agacctcctc gattctcttg
     2701 gctgagatat aggactggtt gagggaattg atcagcatgg ctagcttgac caattccacc
     2761 aaaatctgta agaggtaatt gataagagca atgagagcac cttgactgag tactcctcct
     2821 tgaattgaaa tatagccttg ccagataata acgagaagag ttccattgac aatcagatag
     2881 gtcagaggtg ttaataaact agacaagaaa cctgtctttt cttgtaatct agcataaact
     2941 tggttaaggg tttgaaaaat ctgtaactct cgtttttctt gaccaaaagc acgaataacc
     3001 cgcatccctt gcaattgctg gcgcgtttcc tgaaccagtt ggtccgtttt ctttctgaga
     3061 ctactgtaga gaggattgac caatcgagat aaccctacaa tgacaatggt caaaatggca
     3121 accatgacta agaaccagaa agtcaactca gctgagattc gataagccat aaaaatggca
     3181 ccaaaaacga taatgggcgc tcgtaaaaag agacgcagga attgattgat accagtctga
     3241 atctggtagg tatccgaagt caagcgagta accaaactag aagttgtcag acggtctctg
     3301 ctgtcctttg gcaaggaaag aatatgacga taaagatcgt ttgtcaattc cttagcaaaa
     3361 cctactgctg cctttgctga gtaaaattga gctatcaagg ccactaaaac gccaattact
     3421 gcaaagataa ggagcaggcc aatctgcatc cagagatgac cttgatctcc ctgaggtaaa
     3481 gattggtcaa caatcccagc aatcaccatg ggaaccaaga gctcaaaaac agcttctaac
     3541 agcttgaaca agggggctaa aattgattcc ttgatgtagg gtttgaagta agataatagg
     3601 tgtttcataa atcccttcta ttcatattct agaaatgaag aaagtgggaa gccccactct
     3661 ctgttttatt tgtttaagta aggcaataga tagccatatc ctgctttttc catctcatcc
     3721 ttggccacaa agcgtaaaga agcagaattg atacagtaac ggaggccgcc taactcccgc
     3781 ggtccatctg tgaaaacatg acccaagtga gcactgcctg aacgagaacg aacttcaatt
     3841 cgctccattc catggctcag atccttgtaa taatgaatca actctttgga aatcggacgg
     3901 ctaaaacttg gccaaccaca acctgaagca aacttatcct tggcaaaaaa gagtggctca
     3961 cctgtcgtaa tatctacata aatcccctct tcaaaggttt ggtcataggc attggtaaat
     4021 ggagcctctg tagcagcttc ttgtgtgaca cgataagact cttcagatag actggccttc
     4081 aacacctctt gactaggctt ttcatagttt gctgcatcaa tcaatggctt atcagcatcg
     4141 gtcacatcga tatgacagta acctgaagga ttcttcctga gatagtcttg gtggtagtct
     4201 tcagccagaa tgtagtggcg taattgctcc acttctactg caatctttcg acccagcatg
     4261 cgttcctgct cctgcaccac tgtgtagata gctggcaaat ctgcttcatc ctgataataa
     4321 atcccagttc gatattggcg accacggtca ttcccttgtt gattgataga tagaggatcg
     4381 ataactcgga aataataaag taaaatctct ctgagtgaca cttccttctc atcgtaaatc
     4441 acttggaccg tttctgcatg gtctgtttcc ttgatcaact ggtaattggt cgtttcgact
     4501 tgaccattag cgtagccaac actggtttct agcactccag aaatgcgtga aaaatattcc
     4561 tctaggcccc aaaaacaacc acctgctaga taaatttctg ccatctttat ttctccttta
     4621 tcacgttttt aactaatact cttcgaaaat ctcttcaaac cacgtcagcg tcaccttacc
     4681 gtaggtatgt tactgacttc gtcagttcta tctgcaacct caaaacagtg tcttgagctg
     4741 acttcgtcag ttctatctgc aacctcaaaa cagtgttttg agcagcctgc ggctagcttc
     4801 ctagtttgct ctttgatttt cattgagtat aaacttcttt tcacaaaaag gatatgaaac
     4861 cctctggtca agagtttccc catcctatct tctattcttt attttgcttc tacacggaca
     4921 cctttggtat caactctcaa gtcatgcagt tttcctttga aaggttgctt ttccaattct
     4981 gccttaattg ttggcatctt gtcatgagaa gccagaacca taactgtcgg cccagcacca
     5041 gaaaggtagg ttgcataggc cccattttct ttggtcactt gcttaatcat cgcaaattct
     5101 cttaccaagt cctgacgata gcgctcatgg aagaggtctc cctcgattgc ttgcccagcg
     5161 gtcaccatgt ctcctgccaa caaggcagca accgctacat tggcgataga acttgcagca
     5221 acagcttcct tataagacaa ttttttaggc aagacactac ggctgtcgcg agtacgtaat
     5281 tcatagtttg gaatgtaagc tagaaaatca cactctggaa agtctgctac gatagcagag
     5341 acttgccctt caacagaact tgcaataacg agattaccat aaatggctgg agccacattg
     5401 tcaggatgcc cttcaatctt ggtcgctaac tgcaattttt catggtctga taagttgagt
     5461 tgacccagtt ggttggctag ttcaatccca gcaacgataa ccgagctgga agaacccaaa
     5521 ccgcgcgcca aagggacatc actggtcatt ttcaagcgtc ttggttgcaa gtctggtaca
     5581 atttgcaaag cgattttaag caagagatta cgctcgtcat gtggaatcca tttgccaatc
     5641 tggtgttcaa tcagccactc atctcgttct tcgcagacct caatttgaag atacttggtt
     5701 acagctacac cgaccgagtc aaaacctggc ccgatattgg cactggttgc aggtacaata
     5761 atcttcatct tattctccta gcaccttgaa ggtattcaag aggtcgaatt ctgaaacctt
     5821 cttcaattca gctgagacat tttcaagctg ggctttatta atcttgtgtg tgatgataac
     5881 gacacgcgcc ttgtcaccct ctttgccatc ttgaaggatt tgcttaaagg aaatatcttg
     5941 agcattgaag atttcagcca acttcaagac ctgacctttt gagtctagag ccaagattga
     6001 gaaatagtag tttgctttga catcttcagg atttgccaag accaagtcac ggctatattc
     6061 gttgaagtct ttgccaatag taccatcatt caaacgacga acgatacgga caatatcagc
     6121 tacaacactt gttgcagttg gtttttgacc cgcacctggt ccgtagtaca tagactcacc
     6181 aataccgata gattctacaa agacagcgtt cattacgcca ttcacactag caagtgggtg
     6241 cgctttaggt aggaaggttg gagtcacttc tgcagcaata cctgaagaag tttcctcaat
     6301 agaaccaacc aatttcacta cgtaaccaag ctcttgagct acagctacgt cttctggtgt
     6361 gatattgcgg attcccttgt gggctacatc atcaaaggca atcttcatgc caaaggcaaa
     6421 ttggctcaaa ataaccatct tgtaggctgc atcaatccca tctacgtcat tcgtcggatc
     6481 gctttctgca aatcctagac gttgtgcttc cgcaagagca tcatcgtaag accagccttc
     6541 ttccaccatc ttggtcacca tgaagttgga agttccgttg actactccaa gcacgcgcgt
     6601 aattttatca gaagccaagg aatttgctaa agtacgaaga attggaatcc caccagcaac
     6661 tgctgcttcg tagtaaagtg ctaccttgtt agcttgagcg atttctagca attctgcgcc
     6721 atggacagct aaaaggtcct tgttagcagt aacaacgtgt tttccagctt ccaaggcacg
     6781 agtgataaag gttttagcag gctcaatacg ccccatcaat tccactacga tagtaatatc
     6841 ctggtctgat aaaatatcat ccacattggt tacaaagtta aagtcattcc ctgctgcaag
     6901 caagcgattt ttttcatctt catccttgac caatacctta gcaactttga tatctgaatg
     6961 tgctgattga ttgatttttc ctccattttc ctttaggagg aaaggcacac cacttgcaac
     7021 ggtaccaaat cctagtaaag caattttaac tgtcatcttt atctcctcga aattttctaa
     7081 tatagccatt ataacagaat tttgtgaaaa ttcctattat agtaaatcac tatttcagta
     7141 taaaaagaaa aaacgaatca gacgattcgc tcttcttaaa atctgaaaat agctttccag
     7201 aaaagattag ccgatttttt gcagattgag cactgcatcg tgactcatca agacttgacc
     7261 atactcttgt aagactgagc gactgatatc actatcgtct gcaaactcgc gcatacgggc
     7321 caacagccaa gctggatatg ggcttggatg attttcaata tccactaaaa tggtcaaata
     7381 atagcgctcg ttcattttgt agagttcaga agtttccatt tcaaaagtca ctgtcttggc
     7441 aaaagctacc aagtcagcca acttagcaaa agaaaggatg tagtagatgt aaggttcttt
     7501 cttactctca gcttcttgtt cagcctgctc ttgctcttct tccttggctt caacttgctc
     7561 aagagattga atggcttcga tatcatcctt ggttttgtct gcgatgcttt tttccagggt
     7621 tttgataaat tcatctggag acatttgagc caattcttcc atatctggca aatccgataa
     7681 gtcttcaaaa tctagatttt ggtcaatctt tgacttggtc acaaagacat ctaccttatc
     7741 aggttttgga gtcacacgga agctcaacat gcctgtatcc agaaagctat caggcatctc
     7801 tagctcatcc aagatagcat aaaagaactc ttctgttttt tcttgaggaa cgagaaagtc
     7861 agcaatctcc attccacgat ccatcaaatc ctctaaagac atcgtgattt ttaaagttgt
     7921 atcactaatt tgtttcattt tcattgctag taacctcata ctttcagttc tatctattat
     7981 actagatttt tacgatttta tcaaaagaag gctcctctat acggatagat tttccctagg
     8041 gtctttctat aggagactcc aagagaaaat ttctgcagac agatagaaaa agccttcaaa
     8101 atcggctaag agccgatttt gaagacctta tacatcagaa tacttataat ttaaaggttg
     8161 ctacaccgag gatagaacga tttaagtttc tgagaatttg aagactttgc tcaaatttct
     8221 tataacgagt cactccgtac tcttcaacaa gaaggactgt atctctttcc aaaagagatg
     8281 atacatcctg taaatctaca aaatgcattc cttttaaagc ttcttgactc tgtttcaatt
     8341 tatctaggat agctttattt gagctaacga tggtcaattc ctgtccagta tttttgtatg
     8401 acaaaacatc tgctaggtta gcaattgttg taatctctgt tacaaaatca atttgatact
     8461 gagaaaaatc acctactcta ttgattgttg gattaaagag ataaactaac acatttccca
     8521 tcacaaccaa aatcacacaa accactccaa taacaactaa acgaagaatc agatttttca
     8581 catttaagcc aagcgctgtt tcaccatttg cgttcaattc tttagagttg atggtttcca
     8641 gtttttcaat tttcacattt gcataggcat gtttaaattt ctcaatcaac ccatcaattt
     8701 ttttctctaa caagtcattg gcatctttac ttgatgtcaa aattttcaca ccaacccctg
     8761 catcgtcaat catatagtag acggtcaatt ttttccacca atagtcattc gttgaatttt
     8821 tcaaggttgt ttctgtcgtg tctaattcac tggcaatttt tttcaactca ctgggttcta
     8881 catcattgaa aagataagct ccattcaaat taccatcaat caatttccca taaaaatcac
     8941 tataaccacc aatttgatga ttcaaaatcg ttttggccga ctcttttgga ggagtgattt
     9001 tatagataag ataagttgaa taacttgttg tatctttgac agtgttttta ttcctaactg
     9061 ctttaattgt aaatggtaca gcaatgagag caaataaagc gatgagagct aaaatatttg
     9121 cttttcgctt tttataaaga tttgcaaaca aatcagctac tgaataatgt tcaaacatga
     9181 tttttttctc ctttgtttag tagatactag ttttcctttg taagcatttt tgctataaat
     9241 ataatcacaa gaacaattcc ccagaattgc attgtaaata aattgaagaa actttctgaa
     9301 aagctgcttc ttggcataaa gaatagatta ttcaagatga gtagggataa agcaaatagg
     9361 attgtccttg agcgataggc tacttgcagc atggctataa ataatacgcc gagtaagaaa
     9421 ctaagcagaa agactccaat cataccatag tcggtataca actccatgat ataactactt
     9481 ccgataccat gccctttcag gtattccttg ttcaagacaa gataggatag attgtgggca
     9541 taactattac tatcaatagc tagttccaca ctattggttg tatgttcaaa ggcttttcct
     9601 ccgaaaatgg ctcccaaact cccccttgca aaataatcaa gaacaggacc aaaagtaaaa
     9661 ttacggaaat ctcggtaagg gaggctactg ttaaatagaa aacctcgagc cagaacacca
     9721 aaactagtcc cttgtttata gataaagtca agtaagatat cccagaaacc tgtatgggaa
     9781 acttggacat tatcccgtac ataattgagt actcccatcg ctaacatgag aataggagaa
     9841 cctacaaaaa tcgctaactt ttctttaaac ccaatccatt ttcctttttc agtttgctcc
     9901 cgcataaagt aataaacaaa agcaaataaa atacttaaaa taaagggatt tcgtgtccca
     9961 attgccaaat gaatagtatt agctgcaata aaggagacaa gcactgctgt ggcctgcaat
    10021 ttctttggct tggttgccag atacatacac attgcataga ccgtaaaggt agacaaaatg
    10081 taggtaaaat aaggcagttt actttcaaaa tttgcatagt aggcatagta ggaagtctgc
    10141 aaacgataca agagccgttc aaataaccga atgaaataga aaggataagt tagaagaaaa
    10201 actcctagtg atacaaagcg taaccgcttg atataaacct cttttagaga atttcctata
    10261 tttgctactt ttattttctt cctagctatg aagtaacgag ccagaatgcc tcctgtggtc
    10321 aagcccagaa tcgaaaccat gacaactata aaggcaaaac gataggctat tggatgatag
    10381 gtatccaaag caccatccct aaaataatca atggtcggtc ttgataccag aaatacaaaa
    10441 atggttaaat agaaaataaa atggattaag taatacttga tatcattcca acaagcaatt
    10501 aagctactaa ccaacaagaa caataaagta gaaagtaagc taacattatt attattaaac
    10561 agatacacaa ttccacttac tagcgtcaag gcataactga ctatggtcaa actaaataat
    10621 aatcgtttcc catcaatcac ttggtcaccc ccgttctaat gtaatttttt agatttttca
    10681 atatttttca gtaataagaa tcgatataag gaaatattta tgaatagggc caaagcacta
    10741 attcttctcc ccttacggaa aattggattc ctagaaatag caaaggcatg gccttttaaa
    10801 aaacgatgaa tctgagaata ggcttcaaac tgtttatact gatcatctag caacatctta
    10861 tccagaataa agaagtgggc ataggccaat ctgaaaaaag cgacctcttt caagtcagga
    10921 tagtttttca caacttcatt ataaaacttt tggtagatat caatataggc taaatccttc
    10981 tctgcatagg gtttggtcgt aatactatcc cctctatgga aatagtaata atagggttta
    11041 gtattaacca catacttctt ggccaacttg attaaatcaa aatggtaata ggcatcttcg
    11101 taaatcaacc ccttaggaaa ggatagggca gttgcaatct gtctcttgat tagcttattg
    11161 caaatcgtcc caggtatttt ttcacctatg aggtattcct ttagaaatgt ttgagaatca
    11221 cagacaaaat agtcatcctg attggctgac tgtgggcttt catcattagc atagacattc
    11281 atgacaccac agcttgaaac atccgcatct tcttgaacta attgctcata taagctctga
    11341 atcatttctg gatggatata atcatctgag tcaataaaaa tcagataatc cccgtgagcc
    11401 tgcttcatcc catcatttcg tgcttgcgac aatccttcgt tctttttatg aagcactgac
    11461 accctgtcat cttgttcagc gattgagtca cacaagcgac cactttcatc tgttgcacca
    11521 tcatcaacaa gaataatttc cagattttga tagatctgct tctgaatgga agctatcgat
    11581 ttttctaggt actgcgccac attatagact ggcacaatca cactaattaa tgcagtttcc
    11641 atgctactcc tctaatagtt tttctacttg ttcgatttgt tttgtaattg taaattgttg
    11701 aatgaattgg ctagcctcat cgacatcaaa gtttgaggca gaagtcatgt aattagtaat
    11761 cgcctgagct gcctcttgat tgctctcaat gatttgtcca aatcgtcctt cttgggataa
    11821 ttcctcagcc cctccaacgt ccgtagagat aaaagggagt cccagactca aggcctccac
    11881 atacactcca ggaaaacctt cttgtttaga catagacaag agaactttcg tctgagataa
    11941 atactgataa ggattttttt gataaccaag gaaatgtaca tagtcctcaa tcccatactc
    12001 tttgactcgt tttttcagtt cctcttccat atcaccagcc ccgataaaat agagatgata
    12061 gttttttccc tcttggtgta ataatcgtat cacttccact acacggtcag aacccttatt
    12121 ttcctcaatc cgtccgatag tacagatact ttgaggagca atctcgatat cgatcttctc
    12181 ttgagatttt tctagaatag tctgaaaatc atatccattg tagattatct gtaatttaga
    12241 agcataatct ggataaactt ccttgataga attgctggtc ttttttgaaa tccctacaat
    12301 tgtattcgca gcatccaact ggcttctatg tgattctctt ttagagctat ccttaagaag
    12361 ttcttcaata cttccatgaa tccaagatat cttcttgact tctcttcttt tagagaacaa
    12421 cagtggtgga ttcataatgg taaaagaaac ttcaacatca taatcatctt ttacaagcaa
    12481 acgacgagtc agtcttggaa aataaattct cattctccac aaaaaagctc gtaaccatct
    12541 ggtttggcga taatcttgaa gggattttaa aatgcgtaca tgctttggaa cagattcata
    12601 tcccttgtca aagtgctcca tttcaagaat atcaatatca tacttttcta gatccagatt
    12661 tgaaacaatg gttgatagaa tcttctctgc accacctcca agagaaaaag accacataaa
    12721 aaataagatt tttttcttag ccaccatatt ctcccttgta ttctgtataa gacttatcca
    12781 tatcagcgat gacagcatca tgatgcggta cctgcttgtc tgctggtgga ggcgtcatat
    12841 aatccccaaa agcagttctg agatagacat catagccgat tggaataggc atctctgttc
    12901 cttcaaatgg caagaaaaga ttgtcttcaa aagatgtgat tgggtacttg tttctcatgt
    12961 agccaggacc tgagcataat tctgtaatgc catcacaatc agccaaatca tacttagtca
    13021 tttctttctc agcttttttc cagatgcgat aacggagaga ttttggagtc aaacccagta
    13081 aaatgcgact tccccatttc atgagagcac catgcttttc tggaatagtt tgcgcacaaa
    13141 agagtgaata aatcaaggcc caacgaacct gttttttccg ctcagctgga tttttcggat
    13201 aataatccaa aggcaaaaca tccaaggtca gaccatgtgg caaatctaaa tcctgctgat
    13261 aaggcttgat acaggtggtt tccttgtcac gaatggtaat aaaaagatta cgatcaacaa
    13321 aatccttgtg actctttgac aagaaataac gttcatctgc ataacgaggc cataattctg
    13381 ctaatttctc ataatcttta cgaggcataa aaaagtctag gtcgtcgtcc caaggaataa
    13441 atcccttgtt tcgaagggca ccaatagcgc ctccgccaca gagataacag agcaaatcat
    13501 gttctttaca aaaggccaca aaatattcag ccatctccag actacgagcc tgaattgctt
    13561 ttaaatcagt catattgttc attattcttt ctatcgtatc gtttcattat accacaaaca
    13621 aggggtgaaa atctattgca gactgtaaaa aatcaaagcc tgactgctat ccaaatagct
    13681 atcaaacttt gatttttctg tcttatactc ttcgaaaatc tcttcaaacc acgtcagctt
    13741 caccttgccg taggtatagg taactgactt cgtcagtctt atctacaacc tcaaaactgt
    13801 gtttttagca gcctgcggct agcttcctag tttgcacttt aattttcatt gagtattatc
    13861 ttatctcaag cccatttgag cgagcttggt ttgatatttg ttttgatcaa ccagcaagcc
    13921 caagcctcca taaacatcat aggcatctac ccagtcaccc agttctggaa tcgtcaattt
    13981 ttcaatacca ttttttgctc catccaaaac agataaaccg tttgttagga ggaaagtata
    14041 gggtacgttg gttgaggtca tagcaaaaac ctttccaaga gcttcagaac cagtgaaaag
    14101 tttagtggga tctttaattt gctctaaaat tgctgttaaa acttgttgct gtctttttgt
    14161 acggccgtaa tccgcctcat catcatcacg gaaacgagca taattgagca gggtcgagcc
    14221 attcatctgc tgttttccga ctttaatggt ttgggttgga gactcagtct cggtagcgta
    14281 taaatcatct ccgactgtag cttctgttag gggacgccca ttcaatgttg aaaattgagc
    14341 atcaatcgtc accccatcag ggaaaagcgt gtcaatcgct gtggcaaagg cctggaaatc
    14401 aaccaaggcg tagtacttaa tgtccaagtc aaaattatct ttcaagactt ggcgaaccat
    14461 ttctgcccct ttttgcccct cttgttctcc taactcgtag gctacgttta acttgttatc
    14521 tgtctgtttt ctaccattaa tcacttgact ataaccatct atatagacca aattatcacg
    14581 catgaaactg actagcttca ttttcttatc tgagcccccg acatttaata ccataataga
    14641 gtcagttcgt gtctcaacac tgttctggcc gattcgacca tcagtaccca tgattaaaat
    14701 attaactcca tctctagtgt cctgaccatt aaagacttct acttgagctg cccgggcatc
    14761 agcagttttc tttgcgctag catcttggta accacgcaaa aacatgaata ccatggccaa
    14821 agccacacag accaaaagtg aaaaaatcac cataaaaatt cgtttaagac ggagcttccg
    14881 tcttttcttt tttggaggga aagagagtgc ttgtgatttg gattgtgagc gactccggtt
    14941 cgcatagctt ggtaagtcaa cctgctcttc tctttcttgt tccaagctag agctactatt
    15001 tcccctagca agagttagct tttcttgcaa ataggcaaac tcattttttt ctctctcatt
    15061 gagatagtga atatttttta gcaaataatc ataacgcaac tgctcatgat gacttaaggg
    15121 attttcttta ctcatcttct ctcctttcca tggtctgata ttggataaat aggataggca
    15181 cccagaattt tatactggat tccaatcgct tctaattctt tttgggcaaa gtggaccaag
    15241 tccttatcga tataatccac atcgataatg aaaaagtatt cacccagtgc tgtcttgagt
    15301 ggacgacttt caatttttgt caagtcaatt cctcgccaag caaaggtcga cagggcctta
    15361 taaagtgcac ctggaaggtt gtcaggtaat gtcaaggcca aactcatctt ttcagtttgt
    15421 gcttgcaagg gaatactagg cttttcagct cctagaaccc agaaacgtgt gaaattggct
    15481 tccatttcct gaatatcctc ggcaatcagt tccaatccat attcttcagc agaacttcta
    15541 ggtgcaactg ctgcaaaggg ctggtctgga tgttcggaaa taaaacgggc cgcataagct
    15601 gtactagctg ttacctcgat ttgagcctct ggatattgtt catcgatgaa tttctttcct
    15661 tgagccaagg cctgtggatg tgaaaaaatc ttttcaatct tagtatggcc tggaaccacc
    15721 atcaactgct gatgaatagg ctgaacgatt tctgctactg cttggatgtg agcctgatga
    15781 aaaagatagt ccaaggtttc atgaacacta ccctcaatag aattttcaac tggcaccaca
    15841 gaatagtcca ctaatccttg ctcataagcc ttgatgacat ctgtaatgtt ggcaaaagcc
    15901 tgcaattcct catgaggaaa agctgtctgc acaacgtggt gtgaaaatga tcccttggga
    15961 cctagataag ctattttcat cttagttcct ctataatttc ctctgggctt agcttggtca
    16021 catccaaaac ccgactagcc acttcctcat accaagcctg tctttcttga aaaatagcta
    16081 ctagttcttc cttgctatta tttagaaaaa gcggtcgctg attgtcctta tcagctgcga
    16141 tacgtaggta gagggtttca aaatctgctt tcaggtagat gttatctgta ttagtcttga
    16201 gtaagtcacg atttctctga gaaataacca ctcctcctcc agttgacacg acttggtctg
    16261 tttgtagtaa atcagctagg acttctgatt ctacatgacg aaaggctgct tctccctttt
    16321 cagcgaaaaa attcgcaatg gacataccta ggcgcttctc aatcagagca tccatatcaa
    16381 ggtaattagg gtccaagcct cttgcaatag tcgattttcc agcccccata aaccctaata
    16441 acaccttagc catgaatcaa gctctccaaa tcatcaaaga aactaggata gctggtattg
    16501 atggcttctg cacggtcaag ctccacctct ccatctgcaa ccaagagggc tgcgatagct
    16561 gtcatcatgc cgatacggtg gtcaccaaac gtattgactc tagcaccgtg aagagctgat
    16621 ttccctttga taatcatccc atctgccgta ggagtaatat ctgctcccat actatttaag
    16681 gcgtctgcca caacctgaat acggtctgtt tccttgacct tgagctcctc agcatccttg
    16741 ataactgtta caccttgggc ttgagtcgca agcagggcaa taatgggcaa ttcatcaatc
    16801 aatcgtggaa tcaaagcgcc accaatctct gttcctttca agtcagaaga ctcaacaatc
    16861 aaggtagcag atttagcgac tggatcgatt tcagttattt ccaattttcc acccatggca
    16921 cgaatgacat caataatacc ggtgcgagtt tcgttgatcc ccacattctg cagcactaga
    16981 cgagaatttg gagcaatcaa acctgcgact aaccaaaagg ctgcactgga aatatctcct
    17041 ggtacgacca ccttctgtcc tgtcaatttt tgtggcccct ggactgtgat tttcttacca
    17101 tccacactta aatgaccacc aaattgttgc aacatatctt cagtatgatt acgggtgtac
    17161 tctttttcga taataactga ctccccctta gcttgtaagg ctgcaaacat caaggctgac
    17221 ttgacttggg cagaggcaat tggcaactca taatgaatag gtcttaggtt tttcgtccct
    17281 tttaagcgaa ggggaggcaa gtctcgttca gtttgccctg aaatgctgac gcccattttt
    17341 ttcagtggaa gggtcacacg gtccatagga cgtttggaaa gactatcatc tccaaacatc
    17401 tctacttcga aatctgcacc agcaaggaca cctgaaatca ggcgaatcga ggtgccagaa
    17461 tttcccatat taagggcatt ttgtggcgct tttaagccag ccatgcctac accttgaatg
    17521 gtaataaccc catctttatc ctcaatttca acaccaaggt cacgaaaaac ctgcatggtc
    17581 gaaagaacgt cttcacctcg cagaatatca taaaccttgg tctcaccctc agccaaactt
    17641 ccaaagataa tggaacggtg gctgatagac ttgtcacctg ggacgcggat actaccatgt
    17701 aaatggcgaa tgtttgtttt tagtttcata ctggacctca tacttgcaat acttttacct
    17761 attttatcat aaaaagtcag aaattcctta aaaattcctg actttaggat cgttcttttc
    17821 ttatttcagc aattctgaaa ctggttcaaa aacaattttt tcaatgtcag aaaggtaaat
    17881 ggccaattgt tgttgcttgg taaagaattc tgacaagagg ctatttcctt gaatctgttt
    17941 accaaagcct tccatcttag cttggaagga cgcatctggc atttgacctg tctgtgctag
    18001 tttttgaatt tcctcttgaa aggcaagata ttctgtaaag attttgcttg cctcagcatc
    18061 tgctgcaatc gcatctttag ctgctttaac agccttgtat tctggtaatc cgcgtagacc
    18121 gcgactgagt tcgtttgcac tatcgtaaat atttgacatg ttcttctcct tatttgatga
    18181 cgactgtata gtcggtattt tctgttatga gatgctcagc tctttccaag tcttgagcat
    18241 ttttaaatga aatttgtagg attccgtgaa tatcctcacg attttcctcg ttgatgtgga
    18301 tgttaaccaa ggaagttcca cgtagcagtt ccaaaatccg caggatgaca tcttcttcat
    18361 caggaacgtc aacatagagg tcgtaagagc tatccacacc accacgctta tggatttcca
    18421 tggtctggcg ttgttcacgc gcttggttaa aaaagttcca aatttgctct tcatctccct
    18481 tactaatggc ctgaccaatc acttccaaac gttccttgaa atcctcaatt ctatccagaa
    18541 tggtctcgct attggacaag agaatggagg tccacattcc tggctcgctt tccgcaattc
    18601 gggtcatatc tcgaaaacca cctgccgcaa agcgccttgc catctcatgc tcttgagcat
    18661 agaccgcagt ctgctccatg agactagaag ccaaaatatg aggaaaatgg ctaatctgag
    18721 aagtgacacg atcatgctcc ttggcatcaa tctcgataaa acgagcatga agacctgaaa
    18781 gcagatcctt catttcctta agcgtgtcct gacttgtcag gcttgaaggt gtaaagatat
    18841 aataggcatt ttcaaaaaga ttgacatctg ccgaagcagc ccctgtcttg tgactaccag
    18901 ccatgggatg ggccccgaca aagcgaacag acttgccagc caaatactgc tccgccgcat
    18961 ccacaatggt tgacttggtc gaaccagcat ctgaaataat aacgccttct cgcaaatcca
    19021 aattggccaa ctccttaatg aaagcaatag tttgtttgat tggcaagctg aggataatga
    19081 catctgccaa aggagcaaaa ctagcaaaat catccgttgc acggtcaatc ataccttctt
    19141 tcaaggcgat atctctcgaa gcttgactac gattataacc taaaatttca taatctggat
    19201 gatcgcgttt gataccaagt gccatagagg ctccaatcaa cccaagacct gcgatataga
    19261 ttgtttttgc cataggaact ccttaatagt tctttgtata gtctcggtgt ttggctaccg
    19321 cttcttttag ttcctcaaga ttatctgatg agaatttttc gaggatttct tgcgccagaa
    19381 ccgttgctac aactgcttcc atgaccattc ctgcagctgg aagagcagtc ggatcacttc
    19441 tctccacggt tgccttgtaa ggttcgtggg tttcgatatc cacactcata agaggtttat
    19501 aaagagtagg aatgggtttc atgaccccac gaacaacgat gggttgccca ttagtcatac
    19561 caccttcaaa accacctaga ttattggtac ggcgagtata accgtcttct ttagaccaga
    19621 gaatttcatc cataacttgg ctgcctttac gataaccagc ctcaaagcca agaccaaatt
    19681 ccaccccttt aaaggcattg atagagacaa cagcttgagc caatcttgca tccaattttc
    19741 tatcccattg gacataggaa ccaagaccaa ctggaacgcc tccgacgact gtctccacaa
    19801 ccccaccgat ggtatcacca tcacgtttga tttggtcaat atagtccttg atttcctgtt
    19861 ctcgttcttg gttgacaata gaaacttcag actgggcagc tctttgctta atttcagcga
    19921 ctgtcagatt ttcaggaaca tctatttcct taccaccaaa gaccacgaca tggttggcaa
    19981 tctccatatc cagctcagcc aagaggcgtt tggctactgc accaactgcc acccgcatgg
    20041 tggtttcacg agctgatgaa cgctccaaag aatttcgcaa atcatcaaaa cggtacttaa
    20101 tccccccaac caaatcggca tgacctgggc gaggatgagt aattttccgc ttgcttttaa
    20161 ggcggtcttc aatgtcctcc gcagacatga tgtccagcca tttctggtgg tccttattga
    20221 tgacatccat agtaataggc gcccctgtcg tcttcccgtg gcgaacaccc gaagtaaaga
    20281 caacctggtc actctcaatc ttcatacgac caccacgacc gtagccaccc tgacggcgtc
    20341 taagatcctc attgatatcc tcagctgtca atggaagtcc agctggaatt ccctcaataa
    20401 tagctgttag acgggggccg tgtgattctc ctgcagttaa atatctcata cactctcctt
    20461 attttaccaa gtagtctttc atctcttcca gagaaactgg gtgaatggtc gctgaaccaa
    20521 gctctggcac caagaccaat ttcaaggtgt taccacgcgc tttcttgtca tgagtaagag
    20581 cctgataaag cttgtcaact ttccaatttt catagtcaac aggcaagccg aatttctgac
    20641 acatctctgt gatagattgg gtaatgccag ctggcatgag gcctttttcc tcagcaacct
    20701 tggaaatctg taccattccc atggcaacag cctctccatg catgaccttg ccataaccgg
    20761 cagtcgcttc gatggcatgg ccaatagtgt ggccaaaatt gaggtaaaga cgaataccat
    20821 tgtccaactc atcttcaacc accatcttgc gcttcacctg acaagaatgt tcaatcaagg
    20881 tctctgcatg ttccaaaata ctctcaacag aaccattcag tcccgtcaag agagcccaca
    20941 gttctggatc ctcaatcaag ccatacttga taacttcacc catcccttca atcaactctc
    21001 tttttccgag ggtttcaaga acaagtggat caatcagaac cccatctggt tgggcaaagg
    21061 tccccaccat atttttagca aatggtgtgt taacgcctgt ctttccaccg atagaagaat
    21121 caacctgagc tgtcaaacta gtcggaatct gaacaaagtg aataccccgc atataggtag
    21181 aggctacaaa gccagccagg tccccaacaa cgccaccacc aagagcaacg attccatcgc
    21241 tacgagtcag accttgcttg actagaaatt catagacttt ctgaacagta gttaaattct
    21301 ttctttcttc accttctaag aaatcaaaaa cagctacctg aaaaccagca tcttctaggc
    21361 tgagcttgac cttctctgca tagagagagg ctacatggtt atctgtcaca atgactacct
    21421 tttgcggttg ccagagttct cgcaaccact gaccagcctg ggccatacaa cctttttcaa
    21481 tctgaatatc ataaggatga tgaggaatat cgattctgat tttcatagga gagtctccct
    21541 ttctttattg atatttttct gttaaagact gccaaatctc ttctgtcggc attttcttgc
    21601 ctgtccacag ttgaaaagct tctgcagctt gatagagcaa cattcccaga ccattgactg
    21661 ctggattgcc ctgacttcta gcccatttca aaaacggtgt ttcaaagggt tggtatatga
    21721 tatctgcaac taagagagtt tctggtaaga ctatgttttc aggaacagga gaggattggc
    21781 catccatgcc cacactggtg gcattaacta gcaaatccga ctcggcaatc cttgcttgca
    21841 gttcagaaac atattctaaa gcacacaaat ccactttaaa gcctgtctgc tcctgtaact
    21901 tgtctaggta aggtcttgtt ttttccatag aaacggaacg aacaaagacc gaaatctgac
    21961 tgacgccatc caaaatagcc tgtgccaaga ttgatttagc cgcaccacct gcacccagca
    22021 gggtcatctt tttacctgaa attgtaaaag aaggcaagca cttaaaaaat cccttgccat
    22081 ctgtattata tccaattaaa ttgccattct cattgacaac cgtattaacc gcaccaatca
    22141 agcgcgcttc atcgctcagc tcatccaaat aaggaatcac ctgctcctta tagggcatgg
    22201 acagattgat gccaaacatc tggtagcgac gaatattggc cactgtttct accaagtcac
    22261 tcgcttcaat ctcccaagcc acataagcac cgttggtagc tgtcgcctca aaggctctat
    22321 tgtggatgaa gggagaaata gaatgcttaa taggattggc aacaactgca gctaaacgtg
    22381 tatagccatc aagcttcatc caaaatctcc ctgatttttt tcatgctagc tagagaaatc
    22441 tgcccagggg cactaacctc atccagactg gcaaaagacc aactcgaacc agtcacatcc
    22501 gcagtgatac gagagacctt gcccacctta cccatagaaa tggtcacata ttcctgttca
    22561 ggattgagcg ttttaaagcc tcgtgtatag ttcatcaagt ctaagacatc ctgctccgtg
    22621 tgagccatca ccgcaacctt aacaagtttt ggatttagga tcgtcaactc tgacaagatt
    22681 tccatcatgt tctcaggtgt ttcttggaaa ttatggtaac tcaaaacaag atttgggaag
    22741 tccagcattt cctcaaaaac atccttgtag ctatagtact caaaatcaat atagtctggt
    22801 tgatagagtt gcgcaacttc cttgattaga tggatatact cttctggaga aaggtcgatt
    22861 tctccacctt cggagcgagt tcgtagcgtg aaaaccaact cacggcctgc gaatttttca
    22921 aaaatggctg gagctacctg caaaatcgct tctttaggca gatagtcggc acgccattca
    22981 atgatgtcgg catccaggta cctcgtggca tccagagcct gagcctcctc taaacttctt
    23041 ggcattactg aaacgattaa tttcatttac taaccttcat actaatcacc ttgaggtaat
    23101 tactactttc atctttttta ttataggcaa aatctgctgg aagaccatat ttgtttaaaa
    23161 tctggtaact tcttcctgca aagcctttat caatttgttc tgtaaatttc tgacgggaaa
    23221 cattggcagc attggtactg gcaatgataa tccctcccgg atttaaaatc tcaagactct
    23281 gggaaatcaa cttgtgataa tccttggcca cagagaaagt ttgtttttta ttccgagcaa
    23341 agctaggcgg atctaggaca atcacatcgt aggtcaagtt tttgcgtttg gcatatttga
    23401 aatactcaaa gacatccatg actataaaac gacgctcgtc tgtgctgagc ccatttgcct
    23461 gaaaatgcgc ttgagacaat tctcgtgaac gtttggctag atcaacagaa gttgtctggc
    23521 tagctcctcc catggccgca gctactgaaa aagccgctgt gtaggaaaac atattgagca
    23581 aggatttacc catagccaag ccgtcaacta aactaccgcg aacctcatgc tggtctagga
    23641 aaattcctgt catcaagcca tcattcataa agacttgata caggacacca ttttctaaaa
    23701 cagtgaaaaa gtcaggtgct tcttgaccat aaacatgggc agattcatag tccaaaccct
    23761 taaagcggat tttctcataa gcccctaaaa cctcagggaa aacctgtcta aaggcttctg
    23821 atatagtctg acgaatctga taaacataag agttatacca agaaaagacg gcgtagtcgc
    23881 cataaaggtc cactgtcaga cccccaaagc catctccctc ttgattaaag agacgaaagg
    23941 cagttgtcaa atcatcttga tagtaggcgt ttctcttttc tttggctttt ctaaacaacg
    24001 tttcaaagaa agcttgattg aaggccacct tgtctttgct gacaaaccag cccaagccct
    24061 tgttttgctg agaaaggtag gcagtcccaa gaaagtttcc ttcctgaccc tgcacctcta
    24121 cttcctgatc cttaagattg acattctcaa gatcactggc ttctagtaaa actagcccct
    24181 tagcaagctt cttttcaacc cttttgctga ctcttattct attcataact accattatat
    24241 caaactttta gacaattctc aaaaaagaaa ctacccttgc ttttttactc ttcttttaaa
    24301 aaatggtata ctagacttcc tgcaaaacta ggaagtaaat gtgtaagaat cacaataaaa
    24361 aatgctcttc cgtcttggag gagcatttct ttttatcaac gaaaatcaaa taacaaacta
    24421 tgaaactagc ctcaggttaa ctgtgagatt ataggtagag aggttgaatc agcaatatgt
    24481 gtctgtcaaa tttagtgaca aaggtagtag aagaaagatg aagaaataaa tctgcttcag
    24541 tagatatctg gaaaatttga ttttatagaa aagccttttg ttacaaactc aatatactat
    24601 caataaataa tattatagaa gcaacaataa ttaaaatttc acctatttgc atcattctat
    24661 ttcgaactct aaatatatgt tctatcaaaa atacttggat cacacacatt ataggaatta
    24721 acgtttttga aattgaaaaa tatcccaata aataaactat aaacaacaat aatagaacta
    24781 tattatattt cttattcaaa acattcctcc ctatattttt gattaccaat cttaatcatt
    24841 tacaactaca ttctaacaaa ctataaaagc gtttgtcgaa ttgaatttat caagcaagca
    24901 accaactatc tcatcttttt tctatttctg ccaatatgcg tgacaggtaa taatgatagc
    24961 caaaaatagc aagagcaagc aagacgataa gagctcctac tcccaagttg atggcaagga
    25021 taggggagag agactgaacc aagaatatgc tcccaattac aagggccatc aggattgcac
    25081 tataaataaa caataaaact atggcgacta tgccatttga acgattcacc aggtccgtaa
    25141 tgctactcca attggttgac agatttttaa cgtccttaaa gtaatggtgg caagaaagga
    25201 tgacactggc aatgatccag actacaagaa ggtaaatcat cgaaaggatg gacaagccta
    25261 gatatagaga aagaccgagc aaagtcagaa ctggtaaaaa ggactgaaca gcaaagataa
    25321 tccaaaattt cactttcaca taacgagcaa agtcaaaggg taaactcttc agaaaatcaa
    25381 cattttccct ctccaaggac aaggcaattg aatgcaggct ggtgatattg ttattgacaa
    25441 ctgctataaa cactcctaca aaaaacaagg gtaaccagta tggaggatga atgtctggaa
    25501 ctatctgaga atctcggatt ttggaaatca gactgatcat catgagataa ggaaggaaag
    25561 cacttgtaaa aagcactgta atcacaccag tcccctatcc caagagggtg aggtggtagc
    25621 gtaaaaccat acggaaaaag ccctttttag tagttgaaat cctctccttg ctgcgacgtt
    25681 cttttttgac cttctcctca ctgttaagca ggatcacgtc ataaaaacga ggaaggacct
    25741 tctttttggt cagataaagc aggaagagag ttagtcctat ccaagcgagc agacccacta
    25801 aggcttctgt cgaaaaaggc tccactgcta ttttgtaaaa gatatgaaga ggataaagga
    25861 gaaatggaat gtctctaact ttgtcaacaa tacttccaaa agtcgactga agaaagaaga
    25921 taaatattaa aggtatgaga actcctatcc caatcatcac attcgaaaaa atagactgat
    25981 actttctgaa gaccctagtc tgagccaaga aatgtactgc cactaccgtc actaaagtaa
    26041 cagagacaaa taataaggtc aaggacagta gcatcaaagg caaacccagc caaagagaag
    26101 gagctagact aatatagagg gctagaaaat aagctaggat tggtacaatt ccagttagag
    26161 ctggcaagag gacagacaga cctttggcca ttataatctc tgattcttta aaggcatagg
    26221 gcctatagga ggccaggtcc ttactctcat aaaagacatt gtaaaaggca gtgaaagaag
    26281 ttgaaaaggc cagcaccagt aaaatagcaa ccatcgagct aaaataaata ggtatttcct
    26341 caaaaggaaa atgaatggct atattactaa aacagatgag catcaagaga ctggaaaaaa
    26401 tgtaagaact taggactcta gcagaaacat ttactttttt cccaggattc ttagcctgct
    26461 tctttcgtag attagccaga ttagcttctt gagatgaata gaggatattg atatcaacta
    26521 attttttaat gaccttgaga cgcatccgca acctcctctt ttctaccagc aagactaagg
    26581 tagatacttt ccaaaaactg gtctgggtgg tctttcctca agttctctac actaccacaa
    26641 tagatcaaat gccccttttt caaaatagca atccgatcac agacttgctc ggctacctca
    26701 aggacatgag ttgaaaacaa gaccgtcttg cctttttgtg catgttcctt catcatttgc
    26761 ttcaaatcaa aggcggcctg gggatccaaa ccagtcaagg gttcgtccaa aacccaaata
    26821 tcaggagcag acaagagtgc cccaatgaca aagactttct gacgcattcc gtgagaaaga
    26881 gtttcaataa cctgatagcg gttttcagca aaatcaaaaa cgttcaatag cctagctaga
    26941 ctagtctcca agtcagagct agtcagatca taggatgaag cgatcaattc ccaaaattca
    27001 ttggccgtta agcgtaaaaa taagtcaggc gagtctgcta cgtagccaat ctttcgtttg
    27061 atcgccaagc gattttccga taactcctga ccgtctacca aaatacgacc actgctgggt
    27121 gaaatgatac tgactaggga ttttatggtg gtcgattttc cagccccatt atgaccaatc
    27181 aagcccataa tctctccatt ttcaatctgc aaattgagat tactcaaggc ctctttatca
    27241 ccatacaact tactaacatt ttgaaattca atcatgggac aactcctatc tttatctgta
    27301 ttatacatcg ctatactagc actttgatac aaaaaaatca atactttatt ttaagtagtt
    27361 aaaatagttt ccttctatct tacgcaaacg tttgcgccga gagatacttt atgatagaat
    27421 aaagaacaag attgacaagt aagaggaaac atcatgcaaa atcaaacact catgcaatac
    27481 tttgaatggt atctgcccca cgacggtcaa cactggacgc gtctggctga aaatgctcca
    27541 cacctagctc atctggggat cagtcacgtc tggatgccac cagccttcaa ggcaaccaac
    27601 gaaaaagatg tcggctatgg ggtctatgac ttatttgact taggagagtt caaccaaaaa
    27661 gggactgtcc gcaccaagta tggtttcaaa gaagactatc ttcaagccat tcaagccctt
    27721 aaagaacagg gaattcaacc tatggccgat gtagttctca accacaaggc tgctgccgat
    27781 aacagggaag cctttcaggt tatcgaagtt gatcctgtag accgtacagt tgaacttgga
    27841 gaacccttca ccatcaatgg ctggactagt tttaccttcg atggtcgcca agatacctat
    27901 aatggcttcc actggcattg gtaccacttc accggtacag actacgatgc caaacgcagt
    27961 aaatctggga tttatctgat ccaaggggac aacaagggct gggctaacga ggaattggtc
    28021 gataacgaaa acggaaacta cgactacctc atgtatgccg acctagactt taaacatcct
    28081 gaagtcatcc aaaacatcta tgactgggct gattggttca tggaaacgac tggtgtagct
    28141 ggtttccgtt tggatgccgt taagcatatt gactctttct ttatgcgcaa cttcatccgc
    28201 gatatgaagg aaaaatacgg tgacgatttc tatgtttttg gtgaattttg gaacccagac
    28261 aaggaagcca atctggacta tctcgaaaaa acggaagaac actttgacct tgtcgatgtt
    28321 cgtctccacc agaatctctt tgaagccagt caagctggcg caaactatga ccttcgtggc
    28381 attttcacag atagcctggt tgaactcaag cctgacaagg ctgtgacttt tgtcgacaac
    28441 cacgataccc aacgaggaca agcccttgag tctaccgttg aagaatggtt caagccagca
    28501 gcctatgccc tcattttgtt acgccaagac ggccttccat gtgtctttta cggagactac
    28561 tatgggattt caggccagta tgctcaagaa gatttcaaag aaatccttga ccgcctccta
    28621 gccatccgaa aagacttggc ctatggagaa caaaatgact actttgacca tgctaactgt
    28681 atcggttggg tacgttcagg tgctgaaaat caatccccaa tcgcagtcct tatctcaaat
    28741 gaccaagaaa acagcaagtc aatgtttgtc ggtcaagaat ggactaatca aacctttgta
    28801 gatttacttg gtaaccacca aggtcaagtt acaattgatg aggaaggtta tggacaattc
    28861 cctgtctcag ctagatccgt aagtgtctgg gcagtcaata ccatctaata gctcataata
    28921 accaagctag gtccaagcgg atttggcttt tttgtattca caaaaagacc tacccaaatg
    28981 gatagatctt tacttgatta caatttacct gctactgcat ccaacaattc ttggatctta
    29041 gcttggttgc ttcctcctgc catggccatg tctggtttac caccaccacg tccatcgatg
    29101 attggtgcta attctttgac aaggtttcct gcatgaaggt cttttgtctt gcttgctaca
    29161 aggacattga ctttgtcacc gatagcggca actaggacaa gaagatcaga gtagtctttt
    29221 tgtttccagt tatctgcaaa agtacgaagg gcaccggcat cggatacaga cacttgacta
    29281 gcaatgtaac gatgaccgtt gacttcctta gcatctttga agatatcgcc tgcggctgca
    29341 gctgcggctt tttctttcaa ctcagcattt tctttttgaa gttgacgaag ttgttcttga
    29401 agtccttcta ccttgtgagg tacttccttg acttgaggtg ctttcaaggt tgctgcgaca
    29461 gctttaagag catcctcttg ttcacgatag gcttcaaagg cttccttacc agtcactgcc
    29521 aagatacggc gagttcctga accgattcct tcttctttga caattttgaa gagaccaatc
    29581 tcagaagtgt tgccaacatg agtaccacca caaagttcaa tagagtagtc accgatagtc
    29641 acgacacgaa cttccttgcc gtatttctca ccaaagaggg ccatagctcc catttcttta
    29701 gcagtgtcaa tatccgtttc aactgtcttc acttcaagtg cttcccaaat tttctcgtta
    29761 acttgctgtt caatcgcacg aagttcctca gcagttactg cttggaagtg ggtaaagtca
    29821 aagcgaagga attcaacttc gttaagagat cctgcctgtg ttgcgtggtt tccaaggata
    29881 ttgtgaaggg cagcgtgaag caaatgagtc gcagtgtggt ttttcatgac acggtgacgg
    29941 cgattgctat caattgccaa ggtatattct tggttcaagg caagcggtgc aaggacttca
    30001 actgtatgaa gggcttgacc atttggggct ttctgaacat tggtcacagt agccacaatc
    30061 ttacctgact catccaagat ttgtccgtag tcagctacct gtccacccat ttcagcataa
    30121 aatgacgttt ccgcaaagat aagagaggca gttccttctg aaacagctcc tacttctgca
    30181 ttgtcagcaa cgatagctac caatttagaa gacaattggc tagtattgta gttgaagaca
    30241 ctttctacag tgatgttttg aagagtttca ttttgcatac ccattgagcc acccttgaca
    30301 gctgacgcac gcgcgcgttc ttgttgttct ttcatggctg cttcaaaacc ttcacggtct
    30361 acagtcatac cagcctcttc agcaatttct tcagtcaatt caactgggaa cccataagta
    30421 tcatagagtt tgaagacatc tgaaccagcg ataacagatt gacctttttc tttcaagtct
    30481 gctacaatgc cttgggcaaa gtgttgacct gagtgaaggg tacgggcaaa tgattcttct
    30541 tcgctcttaa cgattttctc aataaagtca cgtttctcaa gcacttctgg gtagtagctt
    30601 tccatgattt ttccaacagt tggaaccaat ttgtaaagga aaggctcgtt gattcccaat
    30661 ttttgaccat gcatagaagc acgacggaga agacgacgaa gaacataacc acgaccttca
    30721 tttcctggaa gggcaccatc accgatggca aatgaaagtg aacggatgtg gtcagcgatg
    30781 accttgaagc tcatgttgtc gccatcttgg tcataaacct taccagacaa tttctcgact
    30841 tcacggataa tcggcatgaa gaggtccgtt tcaaagttgg tcttagcccc ttggataacg
    30901 gccaccaaac gctccaaacc agcgcccgta tcaatgttct tatgtggcaa ttccttgtat
    30961 tcgctacgag gaacagcagg gtctgcgtta aattgtgaca aaacgatgtt ccagatttca
    31021 atataacggt cgttttcaat atcttctgca agcaggcgaa gaccgatatt ttctgggtca
    31081 aaggcttccc cacggtcaaa gaagatttct gtatctggtc cagaaggtcc cgcaccgatt
    31141 tcccagaagt tgtcctcaat tggaatcaag tgacttggat ccactcccac ttcaatccag
    31201 cggttgtaag aatctttatc gtctggatag taggtcatgt aaagtttttc agcagggaaa
    31261 tcaaaccatt cagggcttat caaaagctca taagcccaag tgatagcttc gtcacggaag
    31321 taatccccga tagagaagtt ccccaacatt tcaaacatgg tatggtgacg cgcagtcttc
    31381 cctacgtttt cgatgtcgtt ggtacggata gccttttggg cattggtaat acgtggattt
    31441 tcagggataa tggtcccgtc aaagtatttc ttaagggttg ctaccccaga gttgatccac
    31501 aaaagagttg ggtcatttac aggaaccaaa cttactgatg gttctactga gtgacctttg
    31561 gtcgcccaga aatcaagcca catttggcgt acttgtgcac tagatagttg tttcatattg
    31621 tctccttatt tacttgttta atgtgattgg ctttccagca tttccacata gtcaatcgcg
    31681 acacagaggg aaatgactag gtctgcataa gcgtcttcaa gaaccgttac ggtataggta
    31741 gaggtcagat ggaagagttc cttcttaatt tccgcaatca actgatcgcg atcatccagc
    31801 aatttgaaat tcaaatccca gatattgccc tcgatacgaa gacctagatt atcaaactca
    31861 tacttatctc gccaaaaggt caacttctta cgaatgacaa aactcgagcc atccagaagc
    31921 tgaatctcaa aacgaggaag caaggtcaag atttctttac tgatctgact gacttgttca
    31981 ccagccgcat catagatggt aaaagttttg ggaatcttaa aaaatgatcc ctccacctga
    32041 taggcaattt ctcccctgtc atccttgata gcgaagcgtt cgcctccaag acgaaacttt
    32101 tgtttgacaa gaaatgtttt catcaacacc tccaaaaatc aaaagacaag ctcatatcac
    32161 gaagggcgaa aaaccgcggt accaccttca ttcaatgaac ttgtcattct cttgttctta
    32221 tgcaattgta tgattgagta gcatgacttc ctagcttaga tggctcgcag caccgccatt
    32281 tctctggact aagacaagtg aaaatcaatt ctcaactttc ttattatatc gtttttttaa
    32341 tcttgcgtca actggaaatg atctccgttg aattagacca attccctaca tctctgatta
    32401 cttttccagg atatattttt tcttactgcc gtttttcttt ttatcccaaa ttttcatatt
    32461 actaaacaca gctactagaa tatttccaaa tataaaggtg cctatcaccc aatatatgga
    32521 ctcagttgtt aggtattgtc gatccaagcc atcctttaaa tggaatagta tagcagtttg
    32581 gttaacaatc ataaaggttg gccagaaact tttgttgaaa aaagtagaca ttttcattat
    32641 ttgttgccgc tttctgtaag gttaatactc aataaaaatc aaaaagcaaa ctaggaagct
    32701 agcctcaagc tgtacttgag tacggcaagg caacgctgac gtggtttgaa gagtataggc
    32761 ttagtatact actaggcaag caaataagca aataaacaac tagaatagaa aaagataggg
    32821 ctctaaaaac tgacttctat tccttaaaaa cgaaccagct tgactgattc gtcttcttac
    32881 gtttatctcc tacttccgat acattttaaa ctgtaggaag aggtcgctat atttccctgt
    32941 ccatttatgg tcaaatttct cataaatttc taggtgtttc atggtttcaa catcgggata
    33001 gaaggcctta tcttcctttg tttcctctgg gagcaattcc ttcgctggta tgtttggtgt
    33061 tgaatagccg acatactccg cattttggag agcattttca ggtttcaaca taaagttgat
    33121 aaaggcatag gctgagtctt ggtttttaac tgttttggga atgaccatat tgtcaaacca
    33181 aagattgctg gcctctgtcg gtaccacata acgtagattt tcattttttt ctaacatttg
    33241 gctggcttca ccagagaagg tcacgccgat tgcaacgtta ttctgaatca tatagccctt
    33301 catctcgtcc gcaacgatag ccttgatatt tggagtcagt ttgtagagct tatccactgt
    33361 ctcttccaac tgctgcagat ccttggagtt gaggctgtag ccgagggaat tgagtcctag
    33421 tcccagcacc tcacgcgccc catcaaagag catgatagaa ttcttatact ccggcttcca
    33481 aaggtcatcc caatgctcag gcgcttcatc taccatggtt tcgttgtaga caattcctaa
    33541 ggttccccag aagtaaggga tggagaattt attacctggg tcaaaggact ggttgagaaa
    33601 ctctggtccg atattttcga ttccttcaat ttttgaataa tcaagcggaa ccaagaggtc
    33661 ttcgtccttc atcttgttaa tcatgtattc acttggaatg gcaatatcgt aggtcgttcc
    33721 accctgcttt atcttagtgt acatggcttc gttggagtca aaagtctcgt actgaacttg
    33781 aattcctgtt tcttctgtaa actgagtcaa gagttcagga tcgatatagt ctccccagtt
    33841 atagataacc aatttttgac tatctcgact attgatttta ctatctaaat gagtcgcaat
    33901 tccccacaag acaaggataa tcgctgcaat tcctgctaaa aatgaataga tttttttcat
    33961 gcttgctcct ccttctcacg agagataaag taataaccta caactaggat aatactaaag
    34021 agaaagacta gagcagacag ggcattgatt tctaaggaaa tccccttgcg agcacgagag
    34081 taaatctcga ctgatagggt tgaaaagcca tttcctgtta caaagaaggt cacggcaaag
    34141 tcatctaacg aataggtgaa ggccatgaaa taaccagtaa tgatagacgg agtcaggtaa
    34201 ggaagcatga tttccttgaa catctgaaat tgactagctc ccaagtcata ggccgcatga
    34261 atcatgtcgc cattcatttc cttgagtcga ggcaagacca tcaagaccac gataggaatg
    34321 gagaaggcca cgtgactaga tagaacggtc aaaaagccaa gtgaaaactt gagttgggta
    34381 aagagaatca agaagctagc accaatcata acgtcaggcg caaccatgag gatattattg
    34441 agtgatagaa aggcttcttg gtatttctta cgagactggt agatgtaaat ggcaccaaaa
    34501 gtcccgataa tggtcgctat caaggctgat aggaaggcca agaaaaatgt ctgagccaaa
    34561 atcagcatga gtctcccatc tccaaacatg gtttcaaagt gagtccagct aaaacctgta
    34621 aagctattca tatcatcacc agcattaaag gcatagccaa tcaagtaaaa gataggcagg
    34681 tagaggacca gaaagaccag tcccagataa aggttggcaa attttttcat cgttctctcc
    34741 tttccttagt cacccacatg gtgatgaaca tggtcaggat gagaatcaca ccgatggttg
    34801 aacccatacc atagttgtca ttggttagaa aattctgctc aatagccgtc cccaaggtga
    34861 taacgcggtt cccaccaatc aaacgggtca gcatgaagag actcaaactt gggataaaga
    34921 ccgactgaac cccacttcgc acaccgttca tagatagagg gaagatgaca tgacggaagg
    34981 tctcccactt agttgcacca aggtcataac tagcattgat gagattatta tccatgtcgt
    35041 ctaagacatt gaaaatcggc aaaatcataa aggggagctc gatgtagctt gcgacaaaga
    35101 taaaggaaaa atcggtaaaa agcaactgtt gtgaaccaat tccgataaat tccaagaatt
    35161 ggttaataga gccattttga ccaaaaatcc cgataaaagc ataggcttta aggagcaaat
    35221 tgatccaggt aggaaggata atcagcatga gccagagttg acggtgcttg agacgggtca
    35281 aaaagagggc tgttggatag ctgataagca aggtcacaaa ggtcacaatc cctgcataaa
    35341 gcactgagtt gaaactcatt ttgaggtagg tcaagttttg tgacgcaaag taagatttat
    35401 aattttctaa actaaactgg ccttcaatgt tgaaaaagga ttgtccgaaa atcaagacca
    35461 agggtgccaa tacaaagagg gcaatccaaa gcatgtaggg cactacaaag agtttagagc
    35521 ttgttttctt catctctttc ctcctcgatc gcattgatca gacctgcttc ttgctcttcg
    35581 atttccacgt attcttcgat acgagcatcg aactcttctt cggtttcatt gagacgcatg
    35641 atgtggatgt cttctgattc aaagtccaga ccgatttcct cacccacgat ggccttacgg
    35701 gttgagtgga tcatccattc atttccaagt tcgtcatagg cgataatttc ataatgaact
    35761 ccacggaaga gctgggtgtc gaccttaact tggagtttgc cttcttcagg aagggtaatg
    35821 cgcaagtcct ctggacgaat aacgacctca acaggttcat ttggcttcat cccaccatca
    35881 accgcttcaa agcgtttgcc gttaaattcg accaagtagt cctcaatcat ggtacctggc
    35941 aagatgtttg actccccgat aaaggtggca acaaagtggt tgattggctc atcgtagatg
    36001 tccacagggg ttccagactg gacaatctcg ccatcattca taacgaaaat ccagtcactc
    36061 atggcaagag cttcttcctg atcgtgagtg acaaagacaa aggtaatgcc caatcgttgt
    36121 tgtaattcac gcaattcgta ctgcatgtct gttctcaatt tcaagtccag cgctgataaa
    36181 ggctcgtcca acaagaccac acggggttgg ttgatgatag cacgggcgat ggccacacgc
    36241 tgacgttgtc ctccagaaag tttgcggatg gaacgttttt cataaccttc caactgaacc
    36301 atcttgagaa cttccgctac acgctgctcg atttctttct tatcaatttt acgcaagcga
    36361 agtggaaagg caacattttc aaacacattc atatgtggga acaaggcata ggattggaag
    36421 acggtatgta cgtcgcgctt gttggttgga atatcattga tacgaacacc gtctagcatg
    36481 atatctcctg tcgtcgcatc cagtaaacct gcaataatgt ttaggatagt tgatttcccc
    36541 gaaccagatg cacctagaag ggtgtagaat ttcccttctt ccaactcaaa gttgatgtct
    36601 ttgagaacct tggtgttgct gtcttcaaaa actttagaga cgtttttgaa ttcgataatt
    36661 ggttttttca attggcataa attccttctt tttcatagat taaccgatcg gggctctgtc
    36721 aggtccccac tacctcttgc agggagtaaa accacctgca tacatcttcg ctaccgatag
    36781 gctttcaccc aagatccgga cttctctttc aagcgtaata cctgagtgtt ccttgacttt
    36841 ttcgataacc gattggatca agtcctcgta gtctttggcc gttccatctg cgacattgat
    36901 cataaatcct gcatgctttt ctgacacttc tacgccaccg atacgatagc ctttcaagcc
    36961 agcttctgaa attaactgac ctgcaaaatg cccgactgga cgcttaaaga ccgagccaca
    37021 agatgggtat tccaaaggtt gcttgagttc acgtaggtgc gtcaagcggt ccatttcctg
    37081 cttgataacc tgatgggttc ctggagctag ggcaaattta actgacaaga caactgcacc
    37141 agactcctga atagctgaat ggcggtaacc aaaagccaag tctttagcag acagggtttc
    37201 gatttctcca tccttggtca agaccttaca agactgcaag atgtgagcaa tctcgccacc
    37261 ataggcaccc gcattcataa agacagcacc gccaacgctt cctggaatac cacaagcaaa
    37321 ctcaaagcca gttaaactat gacggagggc aatgcgagtt gtttcaatca agttagcccc
    37381 agcttctgct tcaatggtat agccatcaac agaaacgtta ttgagcttgt cacacaagat
    37441 gacaaatcca cgaatcccac catcacgaac gatgatattg cttgcattgc caagaaccat
    37501 ccaagggata ttttcttggt tggcaaattt cacaaggcga gccaactcaa aacgatttcg
    37561 tggaaagacc aaataatcag cctctccacc tacttttgta taactatagc tatgcaaggg
    37621 ttcctgaaaa cggatatcaa ttccttctaa gatttcaagc attttttctc ttacagacat
    37681 gtcactcttc cttttccaaa attcattcca ttataccatt tttagagaca tttgacgacc
    37741 ataaaaatac cttgtttgga ttttgcataa gaaaaagagg ttcccccctt tttatgattt
    37801 tttacaaaag atttccttgg ttccataggc gaccagaacg agctccagtg ctagaatcac
    37861 ttcaaccaag actggatttg tcaaccagcc tacttggaaa agagatggtg ccagatcaaa
    37921 gaaggcatgc aagccatagg ctgttaggag ataaatccat ttcttctggc gaacagcttg
    37981 gtaaacccaa actgtcaaaa gtaattggaa accaagcgcc aagattcgct caaaaccaag
    38041 caaataaatc tgccagaccg aaagtgactg aatggttttt aacatatttt cagacagtaa
    38101 ttgcataacc tgtggattct gagtttgaac tgccgaaaga acaatgtaaa gattgagtaa
    38161 actagtaagg cctagaaaaa tcaactccaa gccaccatgc cccagtccat aggccaaggc
    38221 gtctgccttt tccaaacttc tctttttctc aaaccatttg aagaaaacaa gacgagccgt
    38281 ttcctcaaaa aatgctgcca tggctaggcc atagataata tagataagcg gatgatcttg
    38341 caagagggca atactaccgt ctttttgagg gtgcaaaatc aagatatgca ccagtttttc
    38401 caaaatctgc gaagagacaa agaaagcgac tgcacccaag cccaagacag ctagattaat
    38461 ctggtatttc tttttggcaa accaaatgct tcctatcaga aaagctagca acagcaacat
    38521 ggtaataatg atatgaatgg tcattttctt ctcctattct gccttttcaa tatctttttt
    38581 catctcgtca acattgaact tagcaaacaa gtattgacgg tcttggactg ggaaacgttg
    38641 gtccaactgg tcaactgctc ccacctcgat aatgccttcc ttgatgacaa aatccatgac
    38701 atgtccaccg aaggtcaaat catctgatat gaagtgcaga tggtagcctg ccacactgac
    38761 cccatggaaa atctcaggcg tccagaaacc aacaatagtc cccgcaacat tgtcacgact
    38821 atattccggt tgatgggttg cgacatcagc aaacttggta tcgggtgttg acttaggaat
    38881 catacgcaca tgcatatgta aaaattcccc ccgaatcttg atagagcgga aaagattttc
    38941 cccatcataa taagactcaa ttcgttcttt caattccttg tctgtcatct caaagcgctg
    39001 gcggaaaatg acctctgcct gatgcggtac cactgcagcg taaggaataa gggcatctgg
    39061 tgacacttcc acaatttctg gctggtctcc tgaccctttg gcctgataag ccttgccatc
    39121 caagacaatc aattccccat caatggaatc caaggttccc aaaccaaggt caccatgttc
    39181 tagcaattct cctactgtca tagtaccacc ataaaggcca gccatcaagg ctccaagagt
    39241 attgtattga aataatttca ctggttcctg cacgttctta tccattcact ttcttgtctg
    39301 ttattctata aatcttactc ctaagtatac cacatttgcc cctagatgtg aacgagagaa
    39361 acgttctaga cattgccaag aaggaaaaaa aagggtacaa tgtaacaaaa tcaagggagg
    39421 tctggaatga agaaacaaag caagtacaaa gaggtcgttt cctatctgaa aaatggtatc
    39481 gagtctggac gatttccgac gggtagtcgc ctgccttcta tccgtcaact gagccttgac
    39541 tttcactgca gcaaggacac cattcaacga gccctgctgg aattacggca cgaacaatac
    39601 ctctatgcca agcctcagag tggctactat gtattagaac aagggcaaca tcaagaccta
    39661 gaaatcgagg ttaccgacga acatgccagt gcctatgacg atttccgact ctgtgtcaat
    39721 gaaaccttga ttggccgaga aaactacctc ttcaactact atgacaatca agaaggatta
    39781 gaagacctaa gacagtccat tcacaaactc ctctttgagc aagctctcta ctgcaaggct
    39841 aaccaactag tactgacttc tggaacccaa caagccttat ttatcctctc tcaaatatcc
    39901 tttcctagac aagccaagga aatcttggtg gaacagccaa cctaccatcg gatgaatcgc
    39961 ctcttgattg cacaggggct ggactatcaa acgattgaac gaggcattga tgggattgac
    40021 ttggaggagc tggaaggcca cttcaaaaca ggaaaaatta aatttttcta caccattccc
    40081 cgatttcact atcctctggg acattcctat tctgagcaag acaaacgatc tattcttaac
    40141 ttagctgcca agtatgatgt ctatatcgta gaggacgatt atctgggtga tttggactcc
    40201 aagaagggcc aaaccttcca ctatcttgat acagaggagc atgtcattta tatcaagtcc
    40261 ttctcgacca gcctttttcc tgcccttcgt attacagcac tcattcttcc aaatgctatc
    40321 aaagaagcat ttgtggccta caaaaatatc ctagactacg acagcaacct cattatgcaa
    40381 aaggccctgt cactctatat tgacagtcaa ttgtttgaaa aaaatcgttt ggctcgcttg
    40441 accaatcatg aatcttacca aaaacaaatc gaggaaagga taactaaaac accttgtccc
    40501 cttcctcatt atcccctaca cgatggttta ttgctagacc tgagacagta tcctaaaatc
    40561 gccagtctca aacacagtca actgggcttg gacttctttg aagaggccta tttgagcacc
    40621 tgtccttatc aatttgccaa ggtgtcccta gacaatctgg aaaatgtttt aaactattta
    40681 aaagcagaat tggaatgaca tccaactctg ctttttctta ttcttcaact tcagttagac
    40741 ttgctgcttt ttcaagatag ctttggtaag ttccttcatc cttaagtttt tggatgacct
    40801 tgtctaccac ttctttcaaa tcatcactat tttttctaag agcaacggca ttggcgtcgc
    40861 cgtccttcat cttcaagctg acagttgcga cagctaagcc agcgttttta gcagcataac
    40921 taagtgcaac aggctcatcc atatgaacag catctatttt tccagcctgc aattcattga
    40981 ctgcttcacc catattagtt agggaagtta attgagcttt tggcaattgt tccttgacca
    41041 ttgattctgg aacagtccct ttttgggctg caatattagc actttctagg ctagttaaat
    41101 ccttgtattt ttccacatca gccttacgaa ccaagaaact aatcttgttt tcatagtatg
    41161 ggattgaaaa atcaaagact tcttttctct cgtcagtagc actaattcct gcaactgcta
    41221 ggtcagcctt accagtttga agactggtca aaacattgtc aaaactcatg cttaagattt
    41281 ccaacttaac cccaagttca tcagcgatag cctgagccat gtcgatgtct gcaccgacta
    41341 cctggttctt tccatcaacc aatgattgaa attcaaaggg tgcatagtca ggactggttg
    41401 ccacaactaa tttccccttt tgcttaatgg cctcaacagc tgactgagaa ccattagaac
    41461 ctgactggca agctactaag aagaaacttg caagaaaatt acataaaaca aatatccatt
    41521 tttttgattt cataaataaa caacctttct gttaattttg tataattata acgatatcca
    41581 agttacttgt caagtgtttt ttaaattttt atctcaaaaa tattttttcg ttcaaaaaaa
    41641 ggagccatca gttgatttca agctcctttt tatacagaat taaactattt tatagttcga
    41701 caatcttacc tgtttcaaag tagacaaccc attcacagat atttttagca tagtcaccga
    41761 tacgctccaa gtaggaaata acttggaaat aatcacgacc cgtaacaatg gcttctggat
    41821 ttttcttaat ctcttcagtc gcaaggtcac ggatagtttc aaaatagtgg ttaatttgct
    41881 catccatgga ggccacccgg tatgcgtcgt caacagaacc attaagataa agatcaagtg
    41941 ctgcttccac aacgctttta acttcacgtc ccattttttt aatttcttcc tctacagctg
    42001 ggatgcgttc ttcccccttc atacggatgg ttgcctgggc aatggctaca gcgtgatccc
    42061 ccatacgctc cacatctgat acagccttaa ggacagtcaa gactgtacgc aaatcttgag
    42121 agactggttg ttggagtgcg atcatttcaa atgatttctt ttccagtttc acttcgtatt
    42181 catttacttc tgcatcatct tcgatgacct cttttgccag gtcacggtca tgcgtgacaa
    42241 aagcacgtac cgtacgattg atttgtgaga gcacttcttg tcccatagcg tagaactggt
    42301 tatgtaattt ctctaaatct tcttcaaatt gagatcgtaa catctttcat ctccttatcc
    42361 aaattttcct gtaatatagt cttccgtttc cttgtgttgg ggatcaagga acatctgctt
    42421 ggtatcatta aattcaatca aatctccatc taggaaaaat cctgtcttat cagagatacg
    42481 tgaagcttgc tgcatggaac gggttaccag aagcatggtg tacttgtctt ttagaccata
    42541 caaggtttcc tcaattttac cagctgaaat cggatccaaa gccgaagttg gctcatccaa
    42601 gaggatgatt ttaggactag ttgccaagac acgggccacg cagacacgct gctgttgacc
    42661 acctgacaat ccaatagctg aatcatatag acgatccttg acctcatccc agatagaggc
    42721 accttgcaag gctttttcta cggcttcatc cagaacctgc ttatccttaa ttccattgat
    42781 acgaagcccg tagacaacat tctcatagat agtcataggg aaaggattag gttgttggaa
    42841 aaccattccg atttccttac gtaattcaac cgtatctgta cgcggactgt agatgttgtg
    42901 accattgtac accacggatc cagttgtggt cacctctgga ttgagatctc ccatgcggtt
    42961 gagagacttg aggagggttg acttccctga tccagatgga ccaatcaagg ctgtaatttc
    43021 cttaggttgg aaagataggg aaacactatt caaagccttc tttttattat aatatacgga
    43081 caggtctgat acctgtaaaa tcgcatctgt catacggttt cctttctaac caaagtgacc
    43141 agatacatag tcattggtgg actgtagctt ggcattttgg aaaatagttg cagtcttgtc
    43201 atactcaatc aaatcaccca agtaaaagaa gcctgtatag tcacttgcac gagcagcctg
    43261 ctgcatatta tgcgttacaa tgatgatggt aaagtttttc ttgagctcaa acatggtctc
    43321 ttctagttgc atggtcgcaa tcggatccaa ggctgaggct ggctcatcca ttaagaggat
    43381 atctggctta acagagatgg cacgagcgat acagagacgt tgttgctgac cacctgataa
    43441 ggtcaaggct gacttgtgga gatcgtcttt aacctgatcc cagagggcag cctgacgaag
    43501 ggaggtttct acgatttcat ctaggacttg cttatcctta actccagcac gttcatgcgc
    43561 aaaggtaata ttacggtaaa ttgacttagc aaatggattg gggcgttgaa aaaccattcc
    43621 aatgtgttta cgcatttcat aaacgttgat ttctggacgg ttgacatcaa ttccacgata
    43681 gagaatctgc ccagttactt tagcaatatc aatagtatca ttcatgcgat tgagactgcg
    43741 taagtaggta gatttccccg atcccgacgg accaatcaaa gctgtaattt tatttctttc
    43801 aaattgcata tcaatcccct taatggattc atttttacca tagtaaacat ggacatcctt
    43861 agtagaaagg gctacttttt cttcaggaaa ggtaaggata tgcttctcat cccagttata
    43921 tgttgacatg gcttctcctt taggcagcgg ttaatttctt gtgtagatag cttccgaact
    43981 tacgagctcc aaagttaaaa atcaggataa agatcaggag cacagcggca gaacctgctg
    44041 atacaatggt tccatctgga atagtgcctt cactattgac tttccagata tggacagcca
    44101 aggtttctgc ttgacggaag atagagatgg ggctagtcac actgaggata ttccagttag
    44161 accagtcaag agctggcgcc gattgccctg ctgtatagat cagagctgca gcttcgccaa
    44221 agatacgacc agatgccaag acgacacccg ttacaatacc tggaagcgct tctggaataa
    44281 caacatgaac cactgtctcc cagcgagaaa tcccaagagc cagaccagcc tcacgttggg
    44341 tatggtgaac gtgtttcaaa ctatcctcta cattacgcgt catctgaggc aagttaaaga
    44401 ctgtcaaggc caaggcacct gaaatgattg aaaatccata ctcaaactgg actacaaaga
    44461 tcaagtaacc aaagagaccc accaccactg atggtaaaga ggacaagatt tcaatacaag
    44521 tccgcacaaa gttggtaaca ggaccttttt tagcatattc agccaagtaa atcccagctc
    44581 ccatagaaag aggtacagaa ataatcaagg taatgaccaa taggaaaaag gaattgtaaa
    44641 gctgaatgcc aatcccacca cctgcttgaa aagcagaaga ccttccagtc aagaaagacc
    44701 aagagatatg gggcaagccc cgaaccaaga tatagagaat caaggaagcc aagattgtca
    44761 caatgatgct agcaatcgta tagaggacag ctgttgcaag tttatctaat ttcttagcgc
    44821 gcataatttt tctttcctct ttctttcgta atcaatttaa tcacactgtt aaaaactaaa
    44881 ctcatcaaga gcagtaccaa ggccagtgac cagagaacat tattatttac agttcccatg
    44941 acagtgttcc caattcccat agttaatata gaagttaaag ttgcagctgg tgtggtcaag
    45001 gaagttggga taacagctga gtttccgaca accatctgga tagctaaagc ctcaccaaag
    45061 gcacgcgcca tcccaaagac cactgcagtg aaaataccag aacgggccgc cttcaagatc
    45121 acacgccaga tagtctgcca gcgagtggct cccatagcga aacttgcctc acgataataa
    45181 cgaggaaccg cacgcaagct atccgttgtc ataaaggtta cggtcggcaa aatcatgaca
    45241 aagaggacgg aaatccctga caaaatccca aaaccagtcc caccaaagac actgcgaaca
    45301 aagggaacga cgacttgcaa gccaataaat ccgtacacta ctgaaggaat cccaaccagg
    45361 agttcaatag ctggttgcaa aatcttcgcc ccttttggtg atacttcggt cataaaaact
    45421 gctgcaccaa tagcaaaggg tgttgcgata agggctgaga gaatggtaac gataaaggaa
    45481 cccaaaatca taggaagggc accaaattct ttactagaag gattccaagt tcctcccaaa
    45541 agaaagtcaa agatattcac accattgaca aagaaggtcg acaagccttt ttgcgctacg
    45601 aaaaccaaaa tcatggccac aaggatgact atcaaagaaa gacaggcaaa ggtcaaacct
    45661 tttcctaatt tctccagacg agaattcttt gatggaagca acattttctt agctaattct
    45721 tcttgattca ttattgtctc ccttccaaca ctgtcacagt tccggcagca tctttttcaa
    45781 ccttcatttc cttaatcgga atatacttca atcctttgac aatcccttct tgggtctcat
    45841 ccgagagaac aaaattgaga aattctgcag ctaactcatt gggctgcccc aatgtataca
    45901 tatgctcata agaccacaag ggccaattat tgctacttat attttctgga cttaagtcat
    45961 agccattcaa cttcatgctt ttgaccgaat catctatata ggtaagagat aaataagaga
    46021 tagctcctgg actttttgat acgattgatt ttaccgctcc atttgaatcc tgctcctgac
    46081 tttgcatggc agactgacct tccataatga cagtatcaaa ggtagcacga gagccagagc
    46141 cggctgcccg attgataaca gagatgggta agtccttacc accaacctct ttccaattgg
    46201 ttacctcacc tatgaagatt tgacgaagtt gctctgtcgt taggttatca acatcaacct
    46261 ccttattgac aatcagagcc aagccagcta ccgcgacctt gtggtcaaca agagcagaag
    46321 catcaattcc gtctttttcc tcagcaaata catctgagtt tcctatatca actgccccag
    46381 actgaacctg ggacaagcct gtaccagaac ctcccccttg gacattgacc gtttttccaa
    46441 catggatcgt gccaaattca tctgccgcta cttcaaccaa gggttgcaag gcagttgagc
    46501 caacagccgt tatggattct ccacgatcaa tccagctagc acagcctact aaacaagccg
    46561 tcagccaaaa agcgataaga gacagagcaa gcttttttct ttttttcact gtttttctcc
    46621 tcgaaaataa ttatgaatac tgtgaatttt ttaagtagtt ctttatgagt tgacgcatga
    46681 attcttacca aatttctgcg caattgatta tttatataat ataggctata ttactctttc
    46741 ctaacctcct tttttcatat gtggataaaa tctcttgtct atcccttccc ccattgtcac
    46801 ccattatagt catttcgtgt ctctttttcc cctttttaat gcaagggaaa ttactctcct
    46861 tagatgataa tccaaaagct agaaaggtat ctcaaatctc tctactctcc cagactagtt
    46921 tacaactaaa aggaaaagat tctattttat gagaaatcta gtttacaagc ggtaagaacg
    46981 ctaataacta aacttcttgt actctttgaa aatctcttca aagcagtgtt ttgagctatc
    47041 tatggctagc ttcctagttt gctctttgat tttcatcgag tagtaaaact acatgtgatg
    47101 gcaatcaaga tatcaagaat catcctacta aaaaaatcca tactttcact ataacataga
    47161 ataagatatt tgactagcat tttcatttga atctgaggcc ttttggaaaa taatttttca
    47221 aaacatttcc agtaaccttt gcaaagccca agccattgcc tttaaccaaa acttggtacc
    47281 aaccatttgg cagactttct gccagctgaa cggtttctcc agccgcatac ttgacaaact
    47341 cttcttggcc aatttcaacc gactgttcga cctgactcgg tttcaaggct aaaccaagag
    47401 cgaaactggg ctcaaagcgt ttcttcttaa aagtacccag atgcagtcca ttgcgagcaa
    47461 tcttgagctt ccctaaatct ggcaaaagtt ctggcaagag ataaagctgg tctccaaaaa
    47521 tctgcaagat acccggtaga ttgaccttca aatggttttg ggcaaattcc tgccacaagg
    47581 caacttgttc acggctgagg ttactcttac ttgccttaaa tttaggagct ggattgttac
    47641 ccttaaactg tagatgggca acaaactgac cctctccctt aaactgatga gggtacatcc
    47701 gagccgtttc tggcaggtca ataccagcta ccattccatt gatatgctct actggcaaca
    47761 agtcaaaatc atactcttcc agcaaccaat tgacaatctc ttcgttttcc tcgggtgccc
    47821 aggtacaggt cgaataaacc agacgaccac cttcagctaa catggtcact gcatcctcca
    47881 gaatttctct ttgcaagcta gcacattgac tcggataatc taagctccaa tagtccatag
    47941 catcaggttg cttacgaaac attccttcac cagagcaagg ggcatcaaga acgattaagt
    48001 caaaatagcc tttaaagacc ttgaccaagc ggtcggcaga ttcattggtc accacgacat
    48061 ttgtcgctcc aaaacgctcc atgttttcaa ccaaaatctt agcccgtttg cttgaaattt
    48121 cattggaaac aagtagcccc tcccctgcta gataggctgc cagttgagtt gatttgcccc
    48181 ccggtgcagc agccaagtcc aagaccttca taccaggact gggttgggct acttgagcca
    48241 ccatttgagc agcaggttct tgcgaataaa ctaaacctgt agcatgctca ggcgatttcc
    48301 ctgaaacctt cccatagtgg ccccaagggg tttgagtaat ggcatcagaa aaggaaagtt
    48361 gctcttcttt taagggattg acccgaaagg ccgaaaccgc ttcctcctca aaagaggcaa
    48421 gaaaatctct tgcctcatct cctagtattt ctttatattt ttcaacaaat ccttctggaa
    48481 atttcattta agttcttttc ctttcgtaaa tataggactg aatttcctcc tgcatctcaa
    48541 gaggcaccat catgaccggc tgtctggttt gaaaatcagg agcttcacca aaaagggtca
    48601 caacccgata gcccagactt tcccctaaaa tactagctgc ggcataatcc catggttgca
    48661 gataggtgag ataggtcaac aaacgccctg acaaaatctt ggcaaaacta atggccgcac
    48721 ttccatagac acgaacacca agaaccgctc ggctcaaatc agccagcccc cattcattgg
    48781 tttccagcat accactattc cctgcaatga gaaaatctcc aagtggttta gttttaaaag
    48841 aagctagggg cctatcattt agacaaactg gaaattcccc accaccgtgg taacaatccc
    48901 ctttgaccac atcataaatc agaccaaact gtccctgacc attttcaaaa taagccatca
    48961 taacagcaaa atcttcctgc tgggctacaa aattattggt accatcaatg ggatcaatga
    49021 cccaaacctt gccctcttga accgaggctc gcagacaacc ttcttcagca caaatcttat
    49081 cctcaggata acgggacaaa atctcaccaa ccaagagttc ctgaacttct ttgtccagtc
    49141 tggtcaccaa atctgttgga gaggacttgg tttcaacacg caagtcttcc tgcatatggt
    49201 caagaatgta ctgacctgct ttcttaacaa gctctttagc aaattcaaat ttacttttca
    49261 agagaaatct ttcctttccc tttttctttg gcagcctgaa ctgctcggta aagtgaatag
    49321 ccactaaccg tttcaaattc tcgtcccaaa cgtttctctt cgctcttgct tggcacgacc
    49381 gctttgaatc ccttatagga gtccagtaac tttttagcct ctactttgcc ttcataggca
    49441 gcttcaacat cattaaaaaa agaaagcact gaagcaagtt cttcagtgct ccacgacaaa
    49501 tctagtgggt aactatactg tttgttcatt aactaatacc agctctcatt cttgcttctt
    49561 ttagttcttg cttacgataa ctacgaggga gaaaagcacg aatctcatct tcattaaaac
    49621 cgatttgcat acgcttggca tcaataataa ttggacgacg caaaagacta ggatactgct
    49681 caatcaaatg aagcaattcc gataccgaaa tactctctac atcaatattc aatttttgaa
    49741 aaatttttga acgagttgaa atgatgtcat cagtaccatt ttcggtcaag gaaaggatgt
    49801 gttgcaattc ttttcttgtt aaaggactgg tcataatatt gtgttccaca aagggaacct
    49861 tatgtttttc taaccaggtc ttagccttac gacatgatgt acagctcggt gatagaaata
    49921 gtgtaatcat gcttttctct tcttatctat actttgctac ttctattata caaaaaaata
    49981 aggcgcttga ctagggattt ttagaaaaaa agcctatttt ttcaggaaaa ataggctgtt
    50041 tgcgaacgat tgacacaatt ggatttggtt aattcactct taacgatggt tttaaacgat
    50101 atatatattt atatatgtaa attaaaaaca tctttccttt cacttcctac gacttttcag
    50161 acacagatag ccaaagaagc tttcatagag ggcaaaaaag aggaggaagg catgaagaaa
    50221 gaaggtctct ggcaaaatca taataacagg atccttggct ggatcaaaaa gccaggtatc
    50281 atctcccaca aagagaattt gatggaaaag agtaaagaat tggtcaaaac caatcaaaac
    50341 tcccccaagt ccaatcatca caggtaagac tactagagcc aggagacttt ttcgataaag
    50401 agacaaaaag tcctttttca caatcctatt gacaaagaca tagaaacttg gcagtgtcac
    50461 tagagctact agctgaacca aatgaaagag attcttgacc actgcgaaat ggtgcaaacc
    50521 agctgctgac gaacgaaaat caggcatctg taagacctga ctaaaaggat tggtcagata
    50581 attcatcaag atatgaaaat tgtattgaat ggtttctggt tttagataga ctcgattcgt
    50641 taagtttagc cactgaatct ccataggata gaaaatccaa gccagataaa tggtcagaag
    50701 gattgagagg gagaggagaa agagcataga gccccaaaag gtcaatttag ttttcatcaa
    50761 aatcccactc cgcaaggcta gaaaccacat gtgtcggtgc gattggcagg ccagctactt
    50821 cttctgcctt ggtaaaacct gtcgtcacca agagcgttgg aatgccattg tcaatcccag
    50881 cccggatatc agtcaaataa ttgtccccaa ccatgattaa ctcttcacgt tccaaaccta
    50941 agtgctcaac tgccttgtcc ataatgatgg cattgggttt tccgatataa accggcttca
    51001 ctcgtgtcgc tacttcaagc agcgtaatca gtgagccagc acctggcaaa agaccacgtt
    51061 ccgtcgggat gttgaggtca ggattggttc cgataaaatg ggcacccttt tgaatagcaa
    51121 gagttgctgt ggcaaatttt tcatagtcga cttgccaatc cagaccaact accacgtagg
    51181 caggtttttc cttgtcttcc acataaccag ccgccttgat ggcttccttg agtcctgctt
    51241 ctccgacaac atagacggtc ttttcaagcc ccaaatcatt catatagtcg atggttgcca
    51301 aagtcgctgt gtagacagtc gataggggcg tatcgatatt aaaattctga gccaacatct
    51361 ccttaacact ctctggagtg cgggttgtat tgttggttac aaagagatag ggaatgtccc
    51421 gcttttgcaa ttcatgaaca aaagtctctc cagcagggat ttggtctttc cccttataaa
    51481 tggttccgtc taaatcaatt aaatagcctt tatatttcat ctatttctcc ctaagccttt
    51541 tttatttctt gccaagtaat gattgcttgg gcattgataa ccccatcact tgtaatttca
    51601 tgcttgcttt ccagtccagt ccgttcaaca gccgatgtaa tcaccccacc tggtcgaact
    51661 tccttgacat acttgaggtt gattttcttg ggaatatagt gggtcaaaaa atccgctccc
    51721 atgacctcaa aaatccagtc taagtattta ctgttattga catgaccatt catatccaag
    51781 tcgtaaaaac gaacatggta atccttgctg atcgactctt ccaaggactc atacttcggt
    51841 ccacggataa gttttttatc aaaatcagac tggtaaggag ccacaatctc aggttcaaca
    51901 gcatggactt ttcgactgtc gcggtccatg agaacaaagg tcgccatcat atggatgagc
    51961 tcctgccccg cttcattata aatagtaaag cgacggtagc aaaaaagtcg attgtagctc
    52021 aaggcttccg tttcgatggt aatttcttcc gcaaaacgag gcaaacgaac cacctcaata
    52081 tcatattcta cgataatcca gaccagatta tagtcttcca aaatggcctt atcactaact
    52141 cccagttcaa tcgactgcat ccctgaaact tgcagtgaca gcaaaattac atctggaagt
    52201 ttgatatgac cgttcatatc agccatatca aaaggaattt tcattttcat ttgataagtt
    52261 aagcccatga tcctactcca aaataaatcg ttccgctaca gtatctccca aaaagagacc
    52321 tctctttgtc atgcgaacgt ggtcaccctc aatctgcatg aggccttgtt gaaccaaatc
    52381 tctgacaatt tctccataaa gtccagcaaa agactgtcca aatttttcct caaatcgcgc
    52441 catggaaacc ccggatttct tgcggagtcc caagaacatt tcttcttcca tttgctcctt
    52501 ttgactcagg tgatcttctg taatacaagc attgccttcc tcaaccgcac tgagataatg
    52561 acgaatggga ccatgatttt tatagcgtac tccattgaca taaccagatg cccctgcacc
    52621 aataccatag tattcagcat tgtcccagta catgagattg tgacgacttt caaagccggg
    52681 tttggagaaa ttagaaatct cataatgctc aaaacccgct cgctccagct ctgcaatgat
    52741 gtactcaaac atctccgctt ctagttcctc cttaggcaga ggcaatttcc cacgtcgcat
    52801 ccgattcata aagaccgtat ggttttctaa aatcaaacta tacaaactca tgtggggaat
    52861 atccagtcca atggctttag ccacattttc ctttacttgc tccatggtct gaccaggcag
    52921 agcataaatc aaatcaatgg agatgttgtc aaaaccagcc agtttcaggc gatcgatatt
    52981 ttcataaata tccttctcca aatgactgcg cccaatcttt ttcaacatct tatcatcaaa
    53041 ggtctggaca cctagcgaaa cacgattgac agccgaattt ttcaaaacag ctatcttatc
    53101 cgcatccaaa tcgcctggat tggcttcaat ggtcaactct tctaagacag acaagtccaa
    53161 gtttttagtc aagccattca gtaaaacctc cagttgcgga gccgacaggg ctgtcggtgt
    53221 tccaccaccg atataaaggg ttgacaactt ttcaatatca taagaacgaa actcttccag
    53281 cagatgctct aaatagctgt cgactggctg atttttgatg aagacctttg aaaaatcaca
    53341 ataataacaa atctgggtac aaaatgggat gtgcacatag gctgacgttg gttttttctg
    53401 catagtaatt attataccac aaagactaga ttccagataa aaatcaccat ccccagatac
    53461 atagtccgtc cggagatggt gatggtttat tcttctgtta tatcaatcac aatctcttct
    53521 gagtcatcaa gagcttcggc tttttcttgc cattgctcct tgagattatt taattgattt
    53581 tttgatgctt ctgtcgcttg aaaagcatag gatttagctt gagcaagtat actgtccaca
    53641 gtgatttcac ctgactcaac ctgttctttt gttttcagaa caaaatctgt agcctgctcc
    53701 ttaacttctg tcagtttttc acagacttgc tccttggcat actccggatc ttctctcaaa
    53761 tcatctagaa aatcttgagc ctgactgcaa acttgtttgc ccttatcact tgttaaaaac
    53821 aaggcaagag ctgcacctga aacggttcct aaaaggattg aggataattt acccataagg
    53881 attctccttt tttatttttt gaaaaattta cttgcaagac gaagagctga cagacttgca
    53941 ccagtcttga gtgtttttga accagctgat gaagctttct tgctcaagac acgcgcatgg
    54001 tcattgaggt ctgaaacaga tagagataaa tctgcaacag cactgaagag tggatcaatc
    54061 gtagccacct tgacattgat atcatctgcc aagacattga ccttagccaa caactcattg
    54121 gtgtgatgca aggtcacatc cacatctgaa gtcaaggttt taatcgtctt ttctgtttca
    54181 tcgatgacac gaccaagctt ttgtacagta atgatcagat agaccaaaaa gacaatcaaa
    54241 gctagggcaa caagaatata tgcaacttct aacatttagt tttcctcctc tgtaatatag
    54301 taaggggcct tctttcgatt ttgataaata acgatcatta taccgagacc gataaggaca
    54361 actgacagcc attgggacac tcgaaggccg aagaacatga gactatctgt tcgcatacct
    54421 tcgatgacca tacgaccgaa accataccaa atcaagtaaa aggccgtgat atgacctcgt
    54481 ctgagactct tccatttccg tctaaaaatc agaatcaagg caaagccaag cagattccat
    54541 agagactcat aaaggaaagt cggttgacgg tagctcccct caatatacat ctggtcacgg
    54601 ataaagccag gtagataatc cagattatcc actgttgcac cataagcttc ttggttaaag
    54661 aaattacccc aacgccccaa actttgagca atcataacgc taggcgccgc aatatctaga
    54721 aaatcccaag tattgatgag tttacggtca gcaaagatat agagcacaag agccccagtt
    54781 atcaaaccac cgtaaatggc caaaccacca ttccaaatgg caaaaatctc tcctaaattc
    54841 tgactatagt aatcaaatcg gaaaataaca tagtagagac gagctcctaa aatagccaag
    54901 ggaaaggcta ctaagataaa atctaaaata tcgtctggta tgatcttctt tctaggtgct
    54961 tctttcatgg tcaaataaac cgcaagaatc aagcctgtca caatacataa ggcataccaa
    55021 cgaatggcta ggggtcctag ttgaatagca attggatcaa gcattttgca cctcatttcg
    55081 agcgatgaga cttgtcagtc gttcgtcgaa caaacgggtc gcatcaaagc ccatttcctt
    55141 ggcacgataa ttcatggcag ctgcctcaat cacaacagag atattacgac ctgttttaac
    55201 tggaatacga atacgaggaa tggctacgcc agaaacttca agttcctctg cattgtttcc
    55261 aagacgatca aaggtcttat gcgtatcgta attttccaaa tagacagcaa gctgaacctg
    55321 tgaagaatcc ttgacagcac tcgcaccgta gagactcata acatcgataa taccaacccc
    55381 acgaatttca atcaagtgtt tcaaaatttc agctggttca ccccagagag taatctcatc
    55441 cttggcaaag atatcgacac ggtcatctgc taccaaacgg tgaccacgtt tgacaagctc
    55501 aagacctgtc tcgctcttac caattccact atctccctga atcaagacgc ccatcccata
    55561 aatatccatc aagacaccgt gcacactggt acgttctgcc aaacgagaat ccagatagct
    55621 agataactct ccagataaac gactggtagc tgcacggctg gttaaaatag caatcttaca
    55681 ttctctagca gcctttaaca tctcctctgg aaccaccaaa ccacgggcaa caatgactgc
    55741 tggtgtctca gatagaaaca tttttttcaa aacttcataa cggctgttgg aaggcatgct
    55801 gatcagataa gaccactcct tcatccccaa aagttgaatc cgctctggtg tgtagtagtc
    55861 aaaatagcct gtcatttcaa gaccaggtcg cgtaatatcc gctgtattga tttccttttc
    55921 aagcaactct ggttcaccat agacaatatc tagtctaagc ttttcaatca cttcttttac
    55981 taaaaccgac atcatttcct ccttcaaatg agttcttctc tctattatat caaattgtag
    56041 gaggaagttt cagatttttg caggctttgg agtatttatt taaaagaaaa aggactagat
    56101 ttctctagcc tttcattcca attagaattt tttacgttta cgagctactt ctgatttacg
    56161 tttacgtttt acagaaggtt tttcatagaa ttcacgtttg cgtgtttctt gaagagtacc
    56221 agctttagta accgcacgtt tgaaacggcg aagtgcgtcg tcaagagatt cattcttacg
    56281 tactactgtt ttagacattt ttttcactcc cttcaagttc gatatctatt tcattctaca
    56341 cgtaaaagga ataattgtca agcaaaaatg ctgtttaatt ttgatttttt cttccattta
    56401 tacaagagtt gaaagcgttc aatagaacat tgctttttta tttttcgagt aagctaagcg
    56461 cttcagcatc tgcgatgatg gttacatcag ggtgattttg gaggctactt gcaggtaggt
    56521 tctcagtcac tgggccagat actgttccgg caatggcttc tgctttcgac tcaccgtaag
    56581 caaaaagaat aatagacttg gcatccaaaa tgtttttaat ccccattgaa atagcttggg
    56641 ttgggacgtc ttcaatcttg gcaaagaagc gtgcattggc ttcgatagta gactggtcaa
    56701 gttctactag atgcgtttga ctgtcaaatg gagtaccagg ctcattaaag ccgatatgcc
    56761 cattgcgacc gattcccaag atttggaggt caactggatg gtcagccaaa atttggttgt
    56821 agcgttcaac ttcagcttca gcattgtcct taacaccacg aggcaagaaa ctttctttaa
    56881 atggtttttg gttgaacaag ttttcttgca tgaagtaacg ataagactgt ggattgtccc
    56941 catcaaggcc cacatactca tcaaggttga cactggttag atttgaaaaa tcaaggtcac
    57001 tctcaacaat ttccttgtaa aattcaagtg ggctacttcc tgtcgcaagt cctagagttt
    57061 gagctccatt agccaatttt tccttcaaaa tctcaaaagc aacttttcca ccttgaactt
    57121 ggttttcaac tttaataact ttcatctttt catcctccat ttctgtctat atttattata
    57181 tggtatagac caatttttgt caagtgaaaa cgatttaatt tctaaaaaaa gagcgtccaa
    57241 acttgaaacg tgttataatg gataggatta gaacttagaa agaatgaaca gatatatgaa
    57301 tacagctgat tttgatttcc acttgccaga ggaattgatt gcccaaacgc cccttgaaaa
    57361 acgtgatgcc tccaaactcc tcatcgtcaa ccgtgagaca ggagaaatgc aagataaaca
    57421 cttccactct attattaata tgctggaacc tggtgatgcc cttgtcatga acgacacccg
    57481 agttctccct gcccgcctct atggtcaaaa agtggagaca ggaggtcatg tggaacttct
    57541 cctccttaag aacactagtg gagacgagtg ggaagttctg gctaaacctg ccaaacgcct
    57601 caaggtcggt actcgtatca gctttggtga tggccgcctc agcgctgtcg ttacagaaga
    57661 attgacccac gggggacgca ttgtccgctt tgaataccaa ggaattttcc tagaagtctt
    57721 ggaaagtctg ggagaaatgc ctctgccacc ttatatccac gaaaaattag atgaccgtga
    57781 acgttatcaa accgtctacg ccaaggaaag cggctctgct gcagcaccga ctgctggtct
    57841 tcacttcacc aaagaactgc tggcagaaat ccaagctaag ggtgttcatc tagtctatct
    57901 gactctccat gtcggactcg gaacctttag acctgtttct gtggataatc tggacgaaca
    57961 cgaaatgcat tcagagttct atcaactttc tgaggaagct gctgccaccc ttcgctctgt
    58021 caaagaaaat ggtggtcgcg tcatcgctgt cggaaccact tctatccgca ccttggaaac
    58081 tattggttcc aagtttgatg ggcaaatcca agcagattct ggttggacca atatctttat
    58141 caaacctggg tatgagtgga aggtcgtgga tgccttctca accaacttcc atctgccaaa
    58201 atcaactctg gtcatgttgg tttctgcctt tgcaggccgt gaattagtct tagatgccta
    58261 ccaccatgcc atccaagaac actaccgctt cttcagtttt ggtgactcca tgtttattta
    58321 ttgagaaaga atttctctaa atcttctaat accaataaat cgctaagata ttatttcaaa
    58381 gaacatctac aattgaaact ctagctagct gtagaagacg cctagtacat tgaaattaaa
    58441 atgcttcccc ctagcttcga aaatattgcc atagattgcg ttgactctcc aaattgattc
    58501 atctatattt tatttcagct tcctatattt tcttcgctgt ttgtaaatca aaatgcaaga
    58561 cacatgagta gcaccatatt tgttactctt atctgtcctc tcaagagact attatgagtt
    58621 atttcagaat cattcactac tttgaccctg actctcctta gtctcaaaat caaagactta
    58681 tactcttcaa aaatctcttc aaactgcgtc aacgtcacct tggattatat atgtgactga
    58741 cttcgtcagt tctatctaca acctcaaagc agtactttga gcaacctgcg actagttttc
    58801 tagtttgctc tttgattttc attgagtatt aaacaaaaag tgaacaaatc tgaattctaa
    58861 tgtacagaag actaggcttg ttcacttttt tatagtcgct ataagatgac cttatctata
    58921 gctttttata tataattata tataattata tattcagaca tactattatc aattttgtcg
    58981 cagggaggaa tctgttaacg cacccattca ccattatcat tgactctata gccatctata
    59041 cttgtattga ccgctaactc acccgatgca tttacataat accatttacc accaacttgg
    59101 aaccattgat tgactttcat agaaccgttg ctgttgaggt agtaccatga accattaact
    59161 tgtacccaac ctgttgccat ggaaccatca gtattataaa aataccacat accattttct
    59221 tgtttccagt ctgttgttgg agcaactgct ttagctggtt ctactgctac atctgttcct
    59281 tggttagatg taacagatac aggatacgaa ggaatagatg attgctcagg aacaacaact
    59341 ttttcaggtt ctctcgtccc tctccttata cgtcttttta ccatctcttt agtaatttga
    59401 cgagaagtag tttcttcaat tgttccatca cgttcatcta cagtatagat tgtagtaaga
    59461 gtaatttacc aatttctcct acttcttcta cttcttgact tttatcaaga gttgggtcat
    59521 cgagatattc tgtttcgatt ggaatttctt ggacaagaac ttggggcttg gttccttttt
    59581 taacaactct tgtttgagag tcttcttttt gacttaaagt actctcagtt acttgtccac
    59641 tctttccatc tacatcataa gttatcgttg taactgtttt cccattcttt cctagagtaa
    59701 tctcttgctc ctgtcctgca gaaaggtcat tgtctgcttc atatttagta gcacatggaa
    59761 caagaacttc ttcaaccttg cttttagctg gaactttgat aactgtatcc gtggcttgtt
    59821 ttctatcaac agtaacctgt tcggtaacat gaccagtctc tggattaaca tcgtaggtcc
    59881 ttgtcgtagt tacatagcca tcctctccat caattgtaac aggattttca ctacggtctt
    59941 ttgtttcatc tttttcataa cgaattcgcg tacttgaaat tttcttggtt actaccttag
    60001 gtttagtcgc tacttttaca ataatacccc cattgtcagc gtcatcatac tctattccct
    60061 cttctttatc tctagtatca tctctgacat attgaatccc atcagcagca tgaacaaaac
    60121 ttgtattcag attcctccta aaaataaagt tagcccgatt accgcagaac caaaaatctt
    60181 tccgagttta cgtaatgcat agcgcttatt agtattagat tttgccatta catcctactt
    60241 ctagtatagc atcttttcta tcaaacgtta aacaatatac tttatatata aaatagactt
    60301 agaatgatat attgattatt gaactaacac tttaactata tcgtaatcaa tctcatatat
    60361 aaaggattgc agacatctta tctaaataca tgctaatata tttagataca aacattccaa
    60421 cttgataatt ttcactcatc tttcatcatt ccttatacaa ctatgcagta taaatagaat
    60481 agttttctca tcagaatgag actattttaa tattagataa tttgatagaa aaaacatgaa
    60541 taaaattggt tgaatttaat tccctaactc gatagaggat tctattttaa atttaacaac
    60601 agctaggatt acactataaa aagtacatta ccacctgttc ggctggagaa tctagtcgat
    60661 tagctccctc ttagttacaa gcttaaagcg attttttaac taatactaaa ccagattaaa
    60721 gaaggaacta gaacatctgt cttgtactaa tcaatatgct attttaaagt ttcaaataaa
    60781 cttggaatgc taattattat atttacaata aatagttgac ttcgatagaa acagaaaata
    60841 gaattcaaca ttcttcccta cttataccat aataaataag atccgcaaga tagccttttc
    60901 tctctacacc attaacaatg gtttgtagat aggacattcc agccttttcc atgacacgac
    60961 ctgaagctgg gttgagactg gcataacgtg ctctgacctt ttgaaaacct gcttgagtaa
    61021 aacaaaagtc caagatagct ttcaaagtct ctgtcatcat accatttccc cagtaagcct
    61081 tgcctaacac atagccaatt tcacagctta aatcagcctc gtctatctta acgatgctga
    61141 tatctcctat cacttgctct gggttttctt ttagacaaat ggcccattta taatagttga
    61201 gattagtata ggaagcaacc caattgcgaa tcgagtttcg agtgatttcg atatcaggat
    61261 ggggatccca ggtaacatag gtcagattct cagcagatga agcccaattt tgaaacatgg
    61321 cttctgcatc actctccaca aatcttctta aaatcaaacg ttctgtctgt aatatttgcg
    61381 taccgataga tttcatgatg ctacctcact tccttatttc tatgctcgta gtaaaaaggc
    61441 tcaactcagt aacagctaga aaacgagttt gtcttctaat ttcttgacgc agtcgctgcc
    61501 tggtttgaaa tgcgctctag caagcttttt caaacctagt catcgttgca ggggtaagac
    61561 gatgaaatcg aactcttcga gttaccgaat ctgcctcatt ttcttatttc taaactcggg
    61621 gttcaagatc ccccagacct tctctcactt tcttatttca agatgagagg ctgaaaacct
    61681 ccagtggagg tttttcttgc tttttaattt cagggcaaga agctaaaaag gtccccggac
    61741 cttcttcgct ttctcatttc taggctcagg gtaaaaacct ccaatggagg tttttactcc
    61801 caaaagtcat caaatacagt gatgggtaag tggcgtttgt gttggccttt gtgccaccag
    61861 ttttcaatgg tcgcttgagc ttctgggctg attgttttgc cttctaggta gtcgtcaatc
    61921 tctgcgtagg tgactccaag tgcgacttcg tcagctaggc ctggtttatc ttcttctagg
    61981 tctgccgttg ggattttttc ataaagggct ggctctgcgc caagtttctg caagagctgt
    62041 tttccttggc gtttattgag gcggtaaaga gggagaatat ccgcaccgcc gtcaccaaac
    62101 ttggtaaaga aacctgtgat attttccgcg gcgtggtctg ttccaatgac cgctccgcta
    62161 tgggaaccag caagggcata ctgagcaatc atacggcaac gtgccttgat attccccttg
    62221 ttgaagtctg aaacaggact acctgtcgct tcaactgcag ctgtcatggc atcagctgat
    62281 tccttgatat tcacaaccaa gctgacatct ggctggatga aggctagggc tttttgagca
    62341 tctgcttcat cagcttgcac tccgtatggc aggcggacag cgataaattt gtagctgtcg
    62401 tctcccgttt cagctcgcag ttcttccata gctaattgcg ccaaacgccc tgccaaggtt
    62461 gagtcttgtc ccccagaaat ccctagtaca aaggttttta ggaagggatg ttttttcaga
    62521 tatcttttta agaaatcaat agaacgacgg atttcttcct gggcatcaat cactggtttg
    62581 acacccagct cttggataat cgtttcttgc aaactcattc ttcttctcct tcaccaaggg
    62641 cttccttgcg catcttatca atcaagtcca tcttatcttg ccatacatca cgcgccaaat
    62701 ccactggata gtgctgcgga ttgagcacac gcttatactc atcccacaac ttgtcaaatt
    62761 ccttacgggc ataatcctga atgtcagtca aactaggcaa gttgtaaact aatattcctt
    62821 ctttgaagat atccaccaag agaggaacgg catcaaaatt acgaaccgtc ttcttgatgt
    62881 atgtataggt cggatggaac atcttgattt ctgtcatgtc gctaatatcc acaccatcat
    62941 aagtgatata gtcgccttct gacttgcctt tttcacgact ggtaatgcgc cacacctgct
    63001 tcttacctgg cgtagagact ttttccgcat tattagacag cttaatcgta ttgcgcatct
    63061 gaccagtttc atcttcgatt gcaacaatct tgtaaactgc accaagagct ggctggtcat
    63121 aagctgtaat cagcttggta cccacgcccc agacatcaat cttggccttt tgcatcttga
    63181 gattgaggat ggtattttca tctagatcat tagaagcata aatcttagcc tctgtaaatc
    63241 cagcctcatc cagttgctga cggactttct tagaaatgta ggcaatatcc ccagagtcaa
    63301 tccgcacacc cataaagtta atctgatcac ccagctcacg cgccacctga atggcagctg
    63361 gtacaccgat gcgaagggtg tcataggtat ccacaagaaa gacacaattt ttgtgggtcg
    63421 cagcgtaagc cttgaaagct tcatagtcat tgccataaac ctgtaccaag gcatgggcat
    63481 gggttcccaa aacaggaatg tcaaagagct tacccgcacg cacgttgctg gttccattgg
    63541 cgccaccaat cacagctgcg cgtgttcccc agatggccgc atccatttct tgagcccgac
    63601 gtgtcccaaa ctccatcaag ggttcatctt cgataaccga acgaatacga gctgccttcg
    63661 tcgccaccaa ggtctggtag ttgacgatgt tcaaaagagc cgtttcgacc aactgacatt
    63721 gggctagagg tccttccacc tgcacaatcg gttcattagc aaaaaccaaa tccccttctt
    63781 gggcagaacg aacggtcaac tccaacttga aattgcgaag gtaatccaag aacgccccat
    63841 gataaccaag cgactccaaa taggctatat cactatctga aaaacgcaag tcttcaagat
    63901 agttcacaat tctttccaaa cctgcaaaaa ccgcatagcc gttcttaaaa ggctgttggc
    63961 ggaaatacac ctcaaagacc gccttcttat tgtgaatccc ttggtcaaag taaacctgca
    64021 tcatgttgat ctggtacaag tccgtgtgca atgtcaaact atcatctgga tacatacttt
    64081 tcctacttcc ttagctagaa acccatgaaa attttcaaga actttcatgt attccaataa
    64141 attagtacta ttatatcaca ttttagctgg attgagaaaa gagtaacaag ctattctcca
    64201 ctctccaatt catccatatc ttgttcaaat tttttctgag cccattcgcc atagctctta
    64261 agaccaagat tgccaataaa gacccacgga aggtaaatga cataagtaat gacccaagca
    64321 gacaggtatt taaaattcaa aggattgtgc tgataaattt ctatgttgaa ttgataattc
    64381 tgcaacatca aaagagccgt aatagccaag gttaggaaaa aacaacccaa aatcgtaaaa
    64441 tgaaaacgac tatagtaggt cactcccaga taacgggcac ggttaaaaaa gtaaaatgtc
    64501 cctatgatga taacgattag cagcatatta gaattaaaaa ggcttggtgc taatactgaa
    64561 atgatataag ataggagcga caaagcgatg cagatataga aactttcaga gcccgcttta
    64621 ttgatcagtt gttcttctct ttcgtctagt aattgataat aataaaatct atttttcatc
    64681 ttcttcctcc caaaatagtt ggtctagggt tttccctaaa catctgcaaa tagactggca
    64741 gagcgagaga ctgggattgt attttcccgc ctctatcaaa ccaatagtct ggcgtgtcac
    64801 cccgacagcc tctgccagtt gaccttgtgt taaatcacgc tctacccgag ctaattttaa
    64861 ttttaaattt ttagccacct tcgtcctcct tatagtttta atactcatct actctttaaa
    64921 aatccaaact aacacaagct gtcagctatt tattataacc ccattaattt gcactccagt
    64981 attatcttca gccgaaaatc agtattttag gttgtttgaa ataaacttcc tagtttactc
    65041 ttttattttt atttttattt agcattagct ttagtaggat cttttaaacg agtttttatt
    65101 gcttatattt cttgtttagt ttagttggtt tcatatcact attatataat gcttttggaa
    65161 atgagcctag tataagtcaa aaacgtgttg aatagtgaaa gcaggagcat accaatatga
    65221 ctgatttttt actgtatttt aggtatgcaa aataatacta aatgaaacta aaatgaatac
    65281 ttcttgcttt tcttgagagt gaaaaagtac aataaaatga ttgtagtgat tgccacaaga
    65341 tactgactaa tagacatcgt atttgaagcc acaaatacag gtaaagaata aaaaggaaga
    65401 agttcaattg ctttgataaa caaatcatta ctagtattca tcatcgtatt taatatatta
    65461 gggataaaga gtagtaaagc tactaaaata ccaagccact tttcaatttg tataaataga
    65521 aaatgtaaga taatagaaaa taaaacagga ctaacaaaat tgtattgact acaatagcta
    65581 ctataaaatc taatcctaaa tcacctggaa tacccaattt acttactatg actagtaaca
    65641 caatgccatt caaagcataa ataatggaag ctgagatggc atatagaaaa ttagacaaga
    65701 cgtaaatcat ccgattcttc tgttgattat aaaacaaact taccgtattg tgggaaaaat
    65761 ctctactaat gactcgatta gcatgtataa cagccattaa cataccgagc atagcataaa
    65821 agtttgaaat atgcttaata ccaagcgatg tcccttaagt ctttagaata aagaatgtaa
    65881 gcaatatcgg cggtataaac gagataagca aactgagata tattacgcct gatgaatata
    65941 aatttcttat attttcctta agaaaattca atttatttaa tttcatgatt ataaccttcc
    66001 tttattttga acgatttagg taaatatctt taagcgtctc ttttttagtt tcaaaatcaa
    66061 ctactttaat agagttttcg ttaaaaaatt taaaaagctc actactttga atattcccag
    66121 acatagtaat tctcaatccc tcttcctgaa caatatcccc aaattcttgt ttggtaatga
    66181 aaatgtctct atctgtagct gatgaaaaag ctatctcaaa caagaaatta tgactatctt
    66241 ttcctacttt ttgaaatgtc aaaagcccgt tctccaagaa aagaactctc tcacaaattt
    66301 cttcaatgtc ttctaattta tgactcgata ttaaaattcc cacgttttca tttaaagcta
    66361 atttttttag aaccgctaaa actatttgtg atgattcaat atctaaacca ttagtcggtt
    66421 catctaaaat caatatatca ggttccgtaa cgagagttag aagcaaagct aatttttgtt
    66481 ttgtacccaa agaataggtc tttacttttt tattaataga ctgagtcaaa tctaactctt
    66541 ggatcaaact tctaaatctt tcttgattgt agtcaacacc atataaattt gacaaatatt
    66601 ttaaattctc taaacctgtt ttagataaaa ataattttgg ttcttcgatt aaatacccaa
    66661 cattatcact gcttataata ttacctgaag tcggttgatt attttgaaca agaattttca
    66721 tcaacgtact cttaccaact ccatttctcc ctactagacc aacaatttca cccttgttaa
    66781 gtgcaaaatt tatatctttg agaatgattg aatgaccata atgcttactt acatttttat
    66841 tcctacatta atattcatgg tttactcttt gattcttatt gagtttaaaa agttgcgcct
    66901 ctttttaaca atattatatc atatatctaa cttgatgcaa tatataaatg tcattttgta
    66961 aaattttatt aacaaaaaac tctctacaac aaaataatag agagttttct gcttattaat
    67021 ttttttcaaa atatctaaga catcgcttct ttgtttaatt tgataggctt tgatacctaa
    67081 gctccgactt tatcacttaa aaaataaaaa agacagctaa tctcttgcgc atcaagggat
    67141 ttcgccattc tttaatctcg tttaagtgtt gtatatggag ctttgcataa ttttttaaaa
    67201 ctaaacaact acattaagca cgaactgtga cgctggttcc atcttcctta taaagattga
    67261 taagcccctc tttaagagct cgaaccatgt ctcctgattg aacgggttgt gggactttaa
    67321 tagtcaatag ttccattgga tttggagcgc ggtcgatttt attgcctttg gcatcatgca
    67381 aatcttcaat ataggtttca aaatgacgga aacctggacc ataaaactca acttggtccc
    67441 cttcgttaat gacgtttcgt tgacgaatag ttgctgtttg tgccgcatca tcataagaaa
    67501 ccacttcagc gacaaacttg tactcagg
//
LOCUS       DAVAZT010000003        64170 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVAZT010000003 DAVAZT010000000
VERSION     DAVAZT010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 64170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64170
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.003"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(146..493)
                     /locus_tag="VQT45_000145"
     CDS             complement(146..493)
                     /locus_tag="VQT45_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2358552.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(604..2379)
                     /gene="spxB"
                     /locus_tag="VQT45_000146"
     CDS             complement(604..2379)
                     /gene="spxB"
                     /locus_tag="VQT45_000146"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HET2358553.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(2586..4829)
                     /locus_tag="VQT45_000147"
     CDS             complement(2586..4829)
                     /locus_tag="VQT45_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET2358554.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQSLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(4839..5210)
                     /locus_tag="VQT45_000148"
     CDS             complement(4839..5210)
                     /locus_tag="VQT45_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HET2358555.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QVGEFGFACGMNMMHGKMIVE"
     gene            complement(5221..5616)
                     /locus_tag="VQT45_000149"
     CDS             complement(5221..5616)
                     /locus_tag="VQT45_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HET2358556.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTIQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      5800..5898
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            5982..6773
                     /gene="thiD"
                     /locus_tag="VQT45_000150"
     CDS             5982..6773
                     /gene="thiD"
                     /locus_tag="VQT45_000150"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET2358557.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEGMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(6982..7614)
                     /locus_tag="VQT45_000151"
     CDS             complement(6982..7614)
                     /locus_tag="VQT45_000151"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET2358558.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(7607..8410)
                     /locus_tag="VQT45_000152"
     CDS             complement(7607..8410)
                     /locus_tag="VQT45_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET2358559.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(8410..8934)
                     /gene="thiW"
                     /locus_tag="VQT45_000153"
     CDS             complement(8410..8934)
                     /gene="thiW"
                     /locus_tag="VQT45_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HET2358560.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERID"
     gene            complement(8939..9631)
                     /gene="tenA"
                     /locus_tag="VQT45_000154"
     CDS             complement(8939..9631)
                     /gene="tenA"
                     /locus_tag="VQT45_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HET2358561.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(9642..10292)
                     /locus_tag="VQT45_000155"
     CDS             complement(9642..10292)
                     /locus_tag="VQT45_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HET2358562.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAIFPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQKLHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAYGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(10294..11679)
                     /locus_tag="VQT45_000156"
     CDS             complement(10294..11679)
                     /locus_tag="VQT45_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2358563.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIVERVQTVGILLQNPNHQFTMESLFEELVFTMENI
                     GYHLQEIDSKIAEVVQQCRCKDILHRLIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELVYDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGSITWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(11680..12240)
                     /locus_tag="VQT45_000157"
     CDS             complement(11680..12240)
                     /locus_tag="VQT45_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2358564.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGFVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(12502..12590)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(12799..13428)
                     /locus_tag="VQT45_000158"
     CDS             complement(12799..13428)
                     /locus_tag="VQT45_000158"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET2358565.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFGTQSKDDAGGTIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(13430..14212)
                     /gene="thiM"
                     /locus_tag="VQT45_000159"
     CDS             complement(13430..14212)
                     /gene="thiM"
                     /locus_tag="VQT45_000159"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET2358566.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVMIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            complement(14455..15123)
                     /locus_tag="VQT45_000160"
     CDS             complement(14455..15123)
                     /locus_tag="VQT45_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HET2358567.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVDKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(15338..15426)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(15680..16816)
                     /gene="lctO"
                     /locus_tag="VQT45_000161"
     CDS             complement(15680..16816)
                     /gene="lctO"
                     /locus_tag="VQT45_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HET2358568.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(17441..18931)
                     /gene="lysS"
                     /locus_tag="VQT45_000162"
     CDS             complement(17441..18931)
                     /gene="lysS"
                     /locus_tag="VQT45_000162"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HET2358569.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLITKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKTIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(19059..19205)
                     /locus_tag="VQT45_000163"
     CDS             complement(19059..19205)
                     /locus_tag="VQT45_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HET2358570.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAGDTF
                     TSFQ"
     gene            19431..20099
                     /locus_tag="VQT45_000164"
     CDS             19431..20099
                     /locus_tag="VQT45_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2358571.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRILV
                     LAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFYYVVLPQATAVALPSFSANVIFLIKETSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRLRHAGFGNPST
                     LSRK"
     gene            20059..20736
                     /locus_tag="VQT45_000165"
     CDS             20059..20736
                     /locus_tag="VQT45_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2358572.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIEISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLDFTRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GAAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            20737..21494
                     /locus_tag="VQT45_000166"
                     /pseudo
     CDS             20737..21494
                     /locus_tag="VQT45_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            21506..22367
                     /locus_tag="VQT45_000167"
                     /pseudo
     CDS             21506..22367
                     /locus_tag="VQT45_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(22447..23094)
                     /locus_tag="VQT45_000168"
     CDS             complement(22447..23094)
                     /locus_tag="VQT45_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2358573.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(23091..23789)
                     /locus_tag="VQT45_000169"
     CDS             complement(23091..23789)
                     /locus_tag="VQT45_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2358574.1"
                     /translation="MGKLSSHMWRLNKIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDVGGDLFLQLLFLVFLFQ
                     SIFYFTRQKRRFIE"
     gene            complement(23799..24551)
                     /locus_tag="VQT45_000170"
     CDS             complement(23799..24551)
                     /locus_tag="VQT45_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2358575.1"
                     /translation="MKQFVQFYKKDFLSVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(24551..25315)
                     /locus_tag="VQT45_000171"
     CDS             complement(24551..25315)
                     /locus_tag="VQT45_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2358576.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(25411..25814)
                     /locus_tag="VQT45_000172"
                     /pseudo
     CDS             complement(25411..25814)
                     /locus_tag="VQT45_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(25994..26626)
                     /locus_tag="VQT45_000173"
     CDS             complement(25994..26626)
                     /locus_tag="VQT45_000173"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HET2358577.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYRELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(26660..27361)
                     /gene="pyrF"
                     /locus_tag="VQT45_000174"
     CDS             complement(26660..27361)
                     /gene="pyrF"
                     /locus_tag="VQT45_000174"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HET2358578.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQNWN"
     gene            27682..27774
                     /locus_tag="VQT45_000175"
                     /pseudo
     CDS             27682..27774
                     /locus_tag="VQT45_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011516271.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(28096..28809)
                     /locus_tag="VQT45_000176"
     CDS             complement(28096..28809)
                     /locus_tag="VQT45_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2358579.1"
                     /translation="MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFYKYLMETQG
                     KVNDQQALVLLMMCLPFSLALAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTM
                     FLPFLLTFVIMGTTPLILGVTIVHTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQV
                     ISLPAMILVAFLPMLSGLDKTVAKITDYSFMGLFTKFFTKWEGFSWNKTLIPNLTLLI
                     WIVLLLTLITITIRKKKIS"
     gene            complement(28802..29497)
                     /locus_tag="VQT45_000177"
     CDS             complement(28802..29497)
                     /locus_tag="VQT45_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2358580.1"
                     /translation="MTGQFLADKGQSIILGQKSQNLTSGELKRIGLVSDTSGFYEKMS
                     LYNNLLFYSKFYNISKSRVDNLLKRVGLYDSRKMVAGKLSTGMRQRMLLARALINKPA
                     VLFLDEPTSGLDPTTSRTIHELILELKTAGTTIFLTTHDMNEATLLCDYVALLNKGKL
                     VEQGAPSELIQRYNKDKKIKVTDYNGNQITFDFTSLEQVSQADLENIFSIHSCEPTLE
                     DIFITLTGGKLNA"
     gene            complement(29837..31169)
                     /locus_tag="VQT45_000178"
                     /pseudo
     CDS             complement(29837..31169)
                     /locus_tag="VQT45_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812020.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
     gene            complement(31153..31951)
                     /locus_tag="VQT45_000179"
                     /pseudo
     CDS             complement(31153..31951)
                     /locus_tag="VQT45_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824573.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M50 family protein"
     gene            complement(32741..33940)
                     /gene="divIB"
                     /locus_tag="VQT45_000180"
     CDS             complement(32741..33940)
                     /gene="divIB"
                     /locus_tag="VQT45_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HET2358581.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            complement(33950..35008)
                     /locus_tag="VQT45_000181"
     CDS             complement(33950..35008)
                     /locus_tag="VQT45_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HET2358582.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVCWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VAKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQLENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(35010..36362)
                     /locus_tag="VQT45_000182"
     CDS             complement(35010..36362)
                     /locus_tag="VQT45_000182"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HET2358583.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(36466..37107)
                     /locus_tag="VQT45_000183"
     CDS             complement(36466..37107)
                     /locus_tag="VQT45_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2358584.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTFL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNCVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTTSLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(37109..39130)
                     /locus_tag="VQT45_000184"
     CDS             complement(37109..39130)
                     /locus_tag="VQT45_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET2358585.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLSYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLMSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            complement(39201..39500)
                     /locus_tag="VQT45_000185"
     CDS             complement(39201..39500)
                     /locus_tag="VQT45_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET2358586.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSLVSRWNSHSDKGEASAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            complement(39866..40120)
                     /locus_tag="VQT45_000186"
     CDS             complement(39866..40120)
                     /locus_tag="VQT45_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HET2358587.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(40140..41981)
                     /gene="typA"
                     /locus_tag="VQT45_000187"
     CDS             complement(40140..41981)
                     /gene="typA"
                     /locus_tag="VQT45_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HET2358588.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            42143..42868
                     /locus_tag="VQT45_000188"
     CDS             42143..42868
                     /locus_tag="VQT45_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HET2358589.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVQVNELLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     ESNYRPLNQKELQIIKNYLEMSR"
     gene            complement(42908..43135)
                     /locus_tag="VQT45_000189"
     CDS             complement(42908..43135)
                     /locus_tag="VQT45_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2358590.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(43224..43604)
                     /locus_tag="VQT45_000190"
     CDS             complement(43224..43604)
                     /locus_tag="VQT45_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2358591.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(43604..43873)
                     /locus_tag="VQT45_000191"
     CDS             complement(43604..43873)
                     /locus_tag="VQT45_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HET2358592.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            43937..44845
                     /locus_tag="VQT45_000192"
     CDS             43937..44845
                     /locus_tag="VQT45_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET2358593.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(44899..45654)
                     /locus_tag="VQT45_000193"
     CDS             complement(44899..45654)
                     /locus_tag="VQT45_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET2358594.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(45675..46604)
                     /locus_tag="VQT45_000194"
     CDS             complement(45675..46604)
                     /locus_tag="VQT45_000194"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HET2358595.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(46619..47242)
                     /locus_tag="VQT45_000195"
     CDS             complement(46619..47242)
                     /locus_tag="VQT45_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HET2358596.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(47235..48473)
                     /gene="hflX"
                     /locus_tag="VQT45_000196"
     CDS             complement(47235..48473)
                     /gene="hflX"
                     /locus_tag="VQT45_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HET2358597.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(48466..49350)
                     /gene="miaA"
                     /locus_tag="VQT45_000197"
     CDS             complement(48466..49350)
                     /gene="miaA"
                     /locus_tag="VQT45_000197"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HET2358598.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKCFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            49471..49641
                     /locus_tag="VQT45_000198"
     CDS             49471..49641
                     /locus_tag="VQT45_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HET2358599.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(49689..50528)
                     /locus_tag="VQT45_000199"
     CDS             complement(49689..50528)
                     /locus_tag="VQT45_000199"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HET2358600.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPIITLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(50625..51584)
                     /locus_tag="VQT45_000200"
     CDS             complement(50625..51584)
                     /locus_tag="VQT45_000200"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HET2358601.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENTFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(51711..52709)
                     /locus_tag="VQT45_000201"
     CDS             complement(51711..52709)
                     /locus_tag="VQT45_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET2358602.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DLHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQAATTQTDTTSSTASGWVKQDGS
                     WYYFDGNGNLVKNAWQGNYYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYAKNAWQGA
                     YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTA
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDG"
     gene            complement(52759..53376)
                     /locus_tag="VQT45_000202"
     CDS             complement(52759..53376)
                     /locus_tag="VQT45_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2358603.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(53377..55098)
                     /gene="pabB"
                     /locus_tag="VQT45_000203"
     CDS             complement(53377..55098)
                     /gene="pabB"
                     /locus_tag="VQT45_000203"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HET2358604.1"
                     /translation="MHRKTVIDFRTLGERYTFAQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(55167..60854)
                     /locus_tag="VQT45_000204"
     CDS             complement(55167..60854)
                     /locus_tag="VQT45_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET2358605.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEETPKEEAPRTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKSEEKVAVKPESQPSDKPAEES
                     KVEPPVEQAKVPEQPVQPTQAEQPSTPKESSQEDNPKEDRGAEETPKQEESTPDTKAE
                     ETVEPKEETKTAKGTQEEDYVGEALVPEQLPEYKVTEGTLVEESTTELDYKTETTEDP
                     TKYTDEETVLRNGEKGSQVTKTTYKTIGGVKTDQVLSTSTEVTKEPVNQQVIRGTKPI
                     EGTTVETREEIIPFETKEQEDDTLKRGTRQVTQEGVNDKKQITETYKTIRGEKTSDAP
                     TITETVIEKPQDKIIKNGTKELEKPTLEWAKTDKDVLKKSATASYTLTKPAGVEIKSI
                     KVALKDNTGTVVKEVTVEENNLQATLDNLKYYQGYTLSTTMVYDRGNGEETEILEDKE
                     VQLDLKKVEIKDIKETRLMKVDENGNETDSSLLETVPENLTSYYLKITTNHNKVTRLA
                     ITNIEEVTEEETSLFKVTASAPDLIQRDSNNSLSQTYTYYIEKPKASQNNVYYNFKDL
                     VDAMQKNPNGEFKLGSDLNATNVPTPSKSYVTGKFTGHLTSVDGKHFSIHNTARPLFD
                     RVEGGSIKNINLINVNINMPWANQLASLAQTVKNATVENIKVTGTIVGNNNVAGILDK
                     LDDAGIMTNVAFIGKVQSVGDKGWNLAGIASEIYRGNLNKAYADVELKGLNTRAGAIV
                     GHLAHDFNPRDVGAWSNVRNSVAKGTIDVARGDVGGLIGKDWPWGTIDNNISLVNVKR
                     GDIFFGSNDMDDEFVSNWIKPNNATVIGVSSGDKTHKQSSKIKEISQVEADKKIKDMG
                     ITADTFEVTEHLVDKLNRRILRDEEYKTIQDYNANRELVYRNVEKLQPFYNKEWIVNQ
                     GNKLTTDSPLMNKEVLSVTAMKGNDFITDLTDADHIMVHYADKTKDIFTISPKDSQVK
                     QVKEYSVAELGEVVYTPNMVVKDRADLISAIEGILSPIELQSDPIYQRLGRTGDNRVN
                     AIKNLYLEESFKEVKDHLNTFVTKLVENEDHQLNTDEAAKRALIKKIEDNKAAVLLGL
                     TYLNRYYGVKFDNFNIKELMLFKPDFYGKNVSVLDRLIEIGSKEDYIKGSRTQESFRE
                     VVAKNTLSGNLHDFLTYNMKLFTNETDINVWFKKAIENNAYVVEQPSTNPAFANKKYR
                     LYEGLNNGQHGRMILSLLNLKDAHLFMISTYNTISFSSFEKYGKDTEEKRESFKSEIN
                     KRAKEQVNYLDFWSRLATDNVRDKLLKSQNVVPTPVWDNHGAPGGWPDRFGHRKDKPD
                     YAPIREFFGRIDKYHDYKYGYGAYAYIFADPQPMDAVYFVMSDLISEYGTSAFTHETT
                     HVNDRMAYLGGHRHRQGTDLEAFAQGMLQTPAEHGHQGEYGALGLNMAFERSNDGNQW
                     YNPDPTKLQTRDQIDHYMKNYNEAMMMLDYAEAEAVLPKVKGDNSKWFKKIDRETRRP
                     MDRNKLSGPHQWDKVRDLIDAEKTTNLETIDDLVNNNFMTIHGNPGNKVFHPEDFGTA
                     YVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGYYGYEHGFIDYVSSKHQGAANKEN
                     NGLLGDDFIIKKVSNNQFSNLEDWKKQWYGEVLTKSKKGFAPIEINGTQISTYEQLKT
                     MFDEAVTKDLTELNDSSIKDKYRNTVVLKSKVFKALLKNTDGFSGDLFTAPQA"
     gene            complement(60876..61439)
                     /locus_tag="VQT45_000205"
     CDS             complement(60876..61439)
                     /locus_tag="VQT45_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HET2358606.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGVLFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            complement(61555..63246)
                     /locus_tag="VQT45_000206"
     CDS             complement(61555..63246)
                     /locus_tag="VQT45_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2358607.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(63243..63980)
                     /locus_tag="VQT45_000207"
     CDS             complement(63243..63980)
                     /locus_tag="VQT45_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2358608.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
BASE COUNT        19317 a        13918 c        11322 g        19613 t
ORIGIN      
        1 ggaatagaat gctttttgaa agcagatgag tattatatgc aatttcttta tataaaaaga
       61 ccggattgct ccgatctttc aatagttcat attctcaatt tctattttaa aaatagctaa
      121 ggttaacgtc aaatgactac gcgacctatt tcatacgata aaaatcaagc actagaccag
      181 caggtccttg aactaataag gactctgttc cccaatcggt tacagttggt ccgtgtaaaa
      241 cctttatacc aagctcattc aaccgtttgt agttctggtc tacatcctca acctcgatat
      301 gaataatgat tcctgactga aagttttcca aaggaaccaa atgattttgt gacaacataa
      361 ggcagtgact accaatcgta aactgagcaa aaccatcatc agcataatct gcctttttat
      421 ccaaaatatg ctccaagtca gcacagactt ggggaacatt tgaaacgata atatctaatt
      481 gatttaaatt catttactct cctccataaa aagaccgaat tgctccgatc ttttaaagtt
      541 ctgctctatg aaaatcaaag aataaagtct acaagtttca tatttgattt tcggcgagag
      601 gaattattta attgcgcgtg attgcaatcc ttcttcttcc aagaagagac ggaatggtac
      661 gagttcttct gcttcgtatt tttccttgaa ggctttgata gcttcttctg agtgaagttt
      721 tggatccaat tcaagtactt ctactggaag tggacggtgt tgagtgatgc gagcatcgat
      781 gacaacagtt ttaccttctt tgttcaattt aacagcttct gcaacaactg catcgatgtc
      841 ttcgatacgg tcaactgtga atccaacagc tccttgagct tccgcaattt tagcgtagtc
      901 agcgtttgtg aagtctacac caaacaagtg tttgtttgta tcttcgtatt tgttcttgat
      961 gaagccgtac tcagcatttg agaagacaag gttgataact ggaaggtcgt attgaacgtt
     1021 tgtgataacg tctgggtagc acatgttgaa tgctccatca cccatgatgt tccatacttg
     1081 gcgatctgga ttgtctttct tagcagcgat accaccagga agggcaatac ccattgtcgc
     1141 aaagagcgga gatgtacgcc acatattctt aggtgtcatg tgaaggtgac gagtagatgt
     1201 ttgagtagtg ttacctacgt cgattgagta gatagcgtct tgatcagcat gtttgttgat
     1261 tgcattgtaa acttgataca attgcaattc accctcagtt ttaccttcga gtttgttcat
     1321 gtaatcacgc cagttttggt tgttcttaac gtttgcacgc caccatggag ttgattcaac
     1381 tgggtttact ttgtcaagga tagctttagc tgcttgacca gcatcaccaa ggattgaagc
     1441 gtcaagggca tgacgtttac caagtttgta agggtcgata tcgacttgga tgaatttttc
     1501 agtgttcttg aatgcttcgt aaacttcagc aaatgggaag tttgaaccaa ggaaaagaac
     1561 tgtgtctgct tcaaagacca cttcgttggc tggtttccaa ccaacacggt aagcagaacc
     1621 tgtcaaacct tcatagttcc attcgaaagc ttcaaagttt ttaccagttg tgatgattgg
     1681 tgctttgatt ttacgtgaca attcagtaat cacttcacca gctttaacac caccaaatcc
     1741 agcatagata actgggcgtt cagcattgtt caagatttca acagctttgt cgatttcaac
     1801 ttcgttcaaa gcaggagcga tgaatgagcg ttcgtatgaa cctgaaccgt agtatgagtt
     1861 ttcgtcgatt tcttggaaac cgaagtttac tggaatttca acaacagctg gacctttttt
     1921 agaaattgca gcacggcagg cttcgtcaat tacttttggc aattgctcag cgtaagctac
     1981 acgtttgttg taaacagcga taccgttgta cattgggttt tggttaagct cttggaaagc
     2041 atccatgttc aattcgttaa ctggacgtga tccaaggatc gctaggaatg gagtgttatc
     2101 catagctgca tcgtaaacac cgttaatcaa gtgagtcgca cctggaccac ctgaaccaac
     2161 tgcaaccccg attgagccgc cgaatttagc ttgcataacc gctgcaagag cacctgtctc
     2221 ttcgtggcga acttgtaaga agcggatatc tttgtcttca gccaaagcgt ccatcaatga
     2281 gctgagtgtt cctgatggga taccgtagat tgtatctacg ccccatgttt tcaatacgtt
     2341 aagcattgct gcagatgcag taattttccc ttgagtcata atgataactc tccttcaatt
     2401 tttttagatt tggagaatac gattacatag aattggaaac gttctccaaa tttttactat
     2461 tccactgtat catatttatg ctgacttttc taaaaatctg ctcaaaactc tctattctct
     2521 attctaatac agttttgaaa gttctgtcat ttctgtttta taacaaagaa atctagtcat
     2581 tacttttagt ctattttact aaaatttaac agaagggaac tggtcagaac agatacagaa
     2641 ctaaaggcca tggctagacc tgccaattct gggttgagag ccagtccaac acctgaaaag
     2701 actcctgctg caatcggaat tccgacaaca ttgtagataa aagcccagaa aagattgagt
     2761 agaattcgat gaaaggtttt cttactcata tcaaaggcac gaaccactcc taaaagatta
     2821 ttggttgtca acaccaaatc tgctgactcg atggcgatat ctgttccagc tcccatagca
     2881 atccccacat ctgctacact aagggcagga gcgtcattga taccgtcccc aacaaaggct
     2941 actttccctg actgttgcag tttatggatt tcatgggctt tttcttctgg caagacgcct
     3001 gcaatgacct cttcaattcc gatttgatct gcaatagcac gcgccacacc agcattgtct
     3061 cctgtcagca tgactgttcg gagaccacgt ttttttagct gactgatggc tagcttagca
     3121 ttttccttag gaatatcttg caaagcaagc aagcctttga tttcattgtc aacagctaag
     3181 aacacaactg tcttagcttc tttttctagt tcttctagtt tatcttgata agtattagaa
     3241 atatccatac catccagcat tttagcattt ccaagtaaaa cttgttttcc attgattcgc
     3301 cctgaaacac ctttcccgtg caaggactga aaattttcaa cagtttgaaa ctcaagtcca
     3361 gcttcactcg ctcgcttaac gatagcctca gccagtgggt gttgagaagc atcttccaag
     3421 gaggctgcca atccaaacac ttctacttcg tcgccgatga tatctgttac cacaggtttc
     3481 ccttccgtca aagtcccggt cttatcaaag acaagagttt gaactttctg gatttcctgt
     3541 aagacagttc catttttgag gagaaccccc atcttggcac tacgtcctgt ccccaccata
     3601 agggctgtcg gtgttgcaag tcccaaggca caaggacagg cgataatcaa aaccgccact
     3661 ccgtagagaa gagaggacac aaagctagct ccaagcacga ccacactatc cctgagcaag
     3721 acgaaccaaa cccaaaaggt catgattcct aaaatgacaa ctactgggac aaaaatccct
     3781 gaaatcttat ccgtcaagtc ctgaatcggc gcacgacttg tctgagcttt cttcacaaaa
     3841 tccacaatct gagccaaaac agtctctgag ccaacttttt ctgctctaaa gacaagcgtt
     3901 ccactatgat tgatggttga gccaatgaca gtatctccaa ctgtcttgtc cacaggcaga
     3961 ctctcacctg tcaccatgga ttcgtcaata ctagagacac cttctactac gacaccatca
     4021 acagcaatct tttcaccggg acgcactcga atcaggtcgc ctaccttgac ttgttccaaa
     4081 ggaacttgga cataactatc atcactcaag acttctgcgg ttttagcttg caagtccagt
     4141 aatttctcca cagcttggga cgtatttttt ctcatttttt cctcaaaaac tgctcccaaa
     4201 agaacgaaaa agaggataaa tccagcactt tcgaagtaaa cagggagacc agcaaagaga
     4261 gcaactaggc tatagaaata agccactaga gttcccagcg caaccaaggt atccatgttg
     4321 gcattgtgct ttttaaaact ggcccaagca ctctggatat atggcttacc tgcaactaac
     4381 ataataggcg ttgttgctag aaaggttccc caatgcatga cttgatgact aatgctacct
     4441 gtcaacatcc caatcatgag aatcacaaga ggcacagtaa agatactagt aatccaaaaa
     4501 cgttgcagga gagatagaga ttttcgagtc ttctcaacga ctatatagct tcccttttgc
     4561 atcttcatgc cacaagaaaa ttcatgtcgc cctaattctt gaggtgtaaa acgaatgact
     4621 ttctcctcat ctacgccgat tggttccaag ataccttctt cttcaaacag aatttcctta
     4681 taacagtttg aaggagtagc acgatgaaag gtaatctcag ctggaattcc cttttgaagc
     4741 tggatatggg ctggatgata gcctttttca gctcggatac ggattttttg aatgccattt
     4801 tctaagcttg ctttcacaat ttctgtcata gtctccacct actctacaat catcttgccg
     4861 tgcatcatgt tcataccaca agcaaagcca aactctccaa cctgctcagg cgtgatttcc
     4921 actacatact cttcccccat tggcaggttc gcatgtacac caaaatctgg aaaaacaatt
     4981 tgatccagac atggtgaagg atccttgcgg tcaaagacaa tgcgtgctgg cactgatttc
     5041 ttgaggacaa tcaactcagg agtatagcct cccatgactt ccactcgaat ctcttggtat
     5101 ccgttttttt gctgggcttt ttgtccagat ttttcaggct ttttgaaaaa ccaaaacaag
     5161 ataaacgcga taagggcaat acaaataatg gttacaatac tatttaacat gacgtctcct
     5221 ttacatacaa ttacatctta cttctgttac agcacttgat ttcttctctg aaatcacagc
     5281 ttccaagtct tccaagtcag tctgagtaaa ttcacattct acaatcaagt cagccaacaa
     5341 attcctaatc ctacgggaac aaaccttgtc tttgatatct tggacaagta aatcccgact
     5401 ttggtctaga gttaaaaggg ctgaataaac aaaggacttg ccttcttttt tccgagtcag
     5461 acactctttc tcaaccaaac gagccaaaag agtttgaatg gtcgacttgg accagtcgaa
     5521 ccgctctgcc aaaaccctaa tcaaatctgt actggtctgc tccccctgca tccaaataat
     5581 cttcatgacc tgccattctg catctgaaat ctgcattacc atacctccaa aatctacatt
     5641 tgtcaattac actcatcagt atactcttaa aatctacatt tgtcaattat agaaataata
     5701 ttttcttcga aaaatagaat tttaatcatt tgaaaaacga tttgcagtca aatattacta
     5761 tataaacaat aaaaatatgc tatactaaag aaaaaagaaa acaaccacta ggggtgcgta
     5821 aagctgagat taacgactgt tagatccctc tgactcaatc taggtaatgc tagctgatgg
     5881 aagtggaaat gataatgggg actagcagtc ttctattgcc tttctaaaac agactagctt
     5941 gttcttaaga atacaaactt cagttggttg ggaggtttta gatgacttat ttacccgttg
     6001 ctttgaccat tgcagggact gaccctagtg gtggtgctgg cattatggca gatttaaagt
     6061 cattccaagc gagagatgtc tatggaatgg ctgttgtaac cagtcttgtc gctcaaaata
     6121 ccagaggtgt tcagctaatc gagcacgttt ctcctcaaat gttgaaagcc caattggaga
     6181 gtgtcttttc tgatattcca cctcaggctg taaaaactgg aatgttggct actactgaaa
     6241 tcatggaaat catccaaccc tatcttaaaa aactggattg tccctatgtc cttgatcctg
     6301 ttatggttgc tacaagtgga gatgccttga ttgactcaag tgctagagac tatctcaaaa
     6361 caaacttact acctctagca actattatta cgccaaatct tcctgaagca gaagagattg
     6421 ttggtttttc aatccatgac cccgaaggca tgcagcgtgc tggtcgcctg attttaaaag
     6481 aatttggtcc tcagtctgtg gttatcaaag gcggacatct caaaggtggt gctaaagatt
     6541 tcctctttac caagaatgaa caatttgtct gggaaagccc acgaattcaa acctgtcaca
     6601 cccatggtac tggatgtacc tttgctgcag tgattactgc tgaactagcc aagggcaaga
     6661 gtctttacca ggcagttgat aaggccaagg cctttatcac aaaagctatt caagatgccc
     6721 ctcaactcgg tcatggttct ggtccagtca accatacaac ttttaaagat taagaaaaaa
     6781 actctctagt tcccacttta agggaattag agagttttta tactcttcga aaatctcttc
     6841 aaattacgtc agcttccatc tgcaacctca aaacactgtt ttgagctgac ttcgtcagtc
     6901 ttatctaaaa cctcaaggca gtactttgag caacctgcga ctagctttct agtttactct
     6961 ttgattttca ttgagtatta attaggaaag aatgtcatgc aactttgtta aaaaggcttg
     7021 cgtttttgcc tcaatatctt ctgcttgcat caaatcacgt acaacagcta caccagctat
     7081 gccagtgccc ataagctgat caatattctc cgaagtcaag cctccaatag caactactgg
     7141 aatggcaacc gtttggcaaa ttgttttcaa ggtcgatatc agagtaatgg gcgcattttc
     7201 cttggtggtg gttgggaaaa tggctcctgt acccaagtaa tctgcacctg atttctccgc
     7261 ttccagagct cttttaaccg ttttagcggt gacaccgagg attttttcag gacccaagac
     7321 tttgcgagct accgaaactg gtaattcatc atctccgata tgcagacctg ctgcatcaac
     7381 cgcaagacaa acatccaacc gatcatcgat tatcaagggg acctgatagg catctgttat
     7441 ttccttgact tgttttgcca gttgataata ttgattggtt gtgagatttt tttctcgcaa
     7501 ttggactatg gtaacccctg aacggcaggc cgtctcaact tttgcaagaa agctttccac
     7561 ggaatcttga tagcgattgg ttaccagata tagtctaagt gcttctctat tcataaacct
     7621 ctcctttgat ggtatctagc caattttcat ctcttcttag gagcgaaagc tgattgagta
     7681 cttggtaacg aaattcttcc aatcccattc cttgaacaac tattttctca gcagcgatat
     7741 tgagataaga gactgctaag caagaagctt caaaaccagt ctttccttgg ctgagaaaaa
     7801 cggctgttaa ggctccaacc aagtctcctg tccctgttat ccagtctaat tcagtacagc
     7861 cattctccag tacagcaact tgattctccg aaacaataag gtccttgggg ccagtaacta
     7921 agaaagacat accaggatag gtctgacacc agtctttcaa gacttgaagc aaatcctccg
     7981 tttcttgatc tttagcactc gcatcgaccc caacgccgtg gtgctttaat ccaacaagac
     8041 ttcgaatttc tgacatgttt cctttaagga ccgtaggtct atagtctaaa aggtctttaa
     8101 ctaagctctt acgaatggat gaagtcgtta cgccaaccgc atctactacc atcgggagag
     8161 aagattggtt tgcatacgaa gctgccatgc ggattgcttt ttccttctca gctgacaaat
     8221 gccccaaatt gatgaagaga gcctgacttt gcttagtaaa atcaagaact tcacggggat
     8281 catctgccat gacaggtttg catcccagag ccaaaatccc atttgccagc atctcacaag
     8341 aaatctcatt ggtcatacag tgaatgaggg aactagagcc tataggaaaa ggatttgtca
     8401 atgcctgcat cagtctatcc tttcagcaaa gaaatatcct tgcacttttt taaagaattc
     8461 ctgcttgatt aaaaatctaa atgcaataaa ggaaatcgct gtaccaatca aggttgctcc
     8521 gaaaaatcga ggagtgtaga taaaccaact aagcttagca gccgatcctg taaagagcac
     8581 cataacagga taggaaacaa tagaaccaat aatacctgtt cccacaattt ctcccaaggc
     8641 agaaaagtaa aattttcgac cgtacttata aaagagacct gctagaaggg ctccaaaagt
     8701 cgctcctgtg agagctaaag gcggaatccc ttgagtcgtc atacggataa aggctgtcac
     8761 tgtagccata gccaaggcat aaacaggtcc catcatgatt cccgctagaa tattgactac
     8821 actggacatc ggtgccattc cctcaatccg aaagataggt gtaaggacta catcaagggc
     8881 aatcatcata gataaaatgg tcaatttgtg aacttgtagt tggtgctttc tcatgtttct
     8941 attcttctcc tttttctaaa gactgtaaat cgctcttcca tgtctggtgt tggtaagcca
     9001 tctcccaaaa cttggcttcc atatgaacac tgatgtggaa ggcatctagc attttttgct
     9061 tatctgtctc atcactttct cgataaagct gattgaccag tgctccctcc tctctgatct
     9121 gttgctctaa ctcatccgta atataagttt caatccattg ttgatagaga ggatttggtg
     9181 atggtttaag attaagtgat ttgcctatat catggtataa ccaaggacaa ggaagcaagc
     9241 ttgcaaaagc tatggctaag ttcggttctg caaattgcct ataaatatga gaaatgtaat
     9301 gataacaggt tggagcgatt ggatgttgct ccatttcctg gtcgttgatt tccaattcct
     9361 tgaaaaattg ttggcgaata aataactcac cctccactaa accctgagca ttttgtttca
     9421 agagtctttt catctcttgg tttgaagtct tatcagccaa aagatgatag atttctgaga
     9481 aagccttcag atagtaggca tcctgaatca ggtaatagcg gaaaatggca ggttctaaat
     9541 tcccctcttg taattgtaaa ataaagggat gatgaaagga agcctgccaa gctttcttgg
     9601 ataattccat cgcaatatct gtaaattcca taataactcc tttataaaaa tagactggtt
     9661 tgaagcaata aaaagaaaag caggtagatt aattttgttt ttttaggaat ataaaaagtc
     9721 cgatagctat tcttcaactg tgcatgttcg tcatatccgt aagcagatag agctctcagg
     9781 taaagatggc gccacctaaa gactgtcatc agaaccttac tgtaaatcaa gggcgaccaa
     9841 aaatgtagtt tttgaccacg taataggcaa gcttctttga gggacttgat ttcttgctga
     9901 atgagaggaa aagaattgaa taccacaatc aaggcatagg accaagagcg tgatagcccc
     9961 ttttgagcca agtacaagag aagctctttt agtgaaatag aggaaacaaa gacaaggccg
    10021 atacaaactg tcacaaaggc cctcgttcca agcatgactg cctgtgaagc atctccgtgt
    10081 aactgaactg cccagtagtt ggcaaaagat gggaaaatgg caagtatgat catccaagct
    10141 aacattttaa atcgacggta atagagcata aagagaatac aaaatgcgac taccgaaaga
    10201 ttcagagcaa tcgaaggaat gaaagatgtt tccaaggata aaatcagcaa gaagagactg
    10261 ataatcggtg tctgggttgc tactttgacc atactatctc acctcccctt gggtattgct
    10321 actctgagat gtaagtggtt tggtaatggt cacttctttc acatgccgaa gaccctgact
    10381 agtcatctca atccaataat caaccacaga aatcaaaggg tctaaacgat gactaatgag
    10441 cagaaaactt cttccttgat tcctctcctc cacaatccac ttgcaaaaat aatggcaggc
    10501 tctatcatcc aaacctgcaa aaggttcatc tagcaagatc acggaagcct tactggtcaa
    10561 gatggtcagg agctgaagaa ttttttgctg accaccactt aattgatagg gactcttatc
    10621 gactgcctgc tccaaatcaa aatatcgtaa agcttgaaaa atccgctgat ttctttcaga
    10681 atcaggtcca tctaattgaa gctcctctcg cagactgact cggataaact gcttctcagc
    10741 ttcctgaaca acaccagtca gatcacgata caaactcttt ttctttttca ggaccgaacc
    10801 cttccaagta atgctcccct tatacttttg aaattgaaga atagaccgaa agagggttga
    10861 tttcccgaca ccattgtcac ccaggataca ggaaatccct tgatagaatg tgaaatcagc
    10921 aattgaaaag agggggcgat taccaagctc accagtcaca cggttcatat ggaatagttc
    10981 cgggctagaa gcaacttcct ttgaagcaac ctgtgtcatc tcataggaag ggatttgaaa
    11041 cacttccctt agttttccgt ctcttagctc caccatatgg tcgatatagg ctttatagtc
    11101 agataaatca tggtcgcaca aaataactgt cttcccatca tagaccaact cttttagaat
    11161 ctccaatatc tcgattctgc tcttgcggtc aatggaagcg aagggctcat ccaagagata
    11221 gaccctagga ttcatggcaa agaggacagc cagcgctgct ttttgctttt ccccacctga
    11281 taagtgatgg atgagacggt gcaagatgtc cttgcaacga cattgctgga caacctctgc
    11341 tattttagaa tcaatttcct gaaggtgata gccgatattt tccatggtaa aaaccaactc
    11401 ctcaaacaag ctctccatgg taaattgatg attaggattt tgcaagagaa taccaaccgt
    11461 ctggacacgt tcgacgatag aaagctgact gacctcgctc ccatctatca ggacttgacc
    11521 gctataggga agagaactaa cttgggcaat catttgaaag aggctggatt ttccagaccc
    11581 actactccca actaacaagg taaaggcttg cgcatgaaaa gtaaaatcaa acggctcaga
    11641 gaagattggg gactgaatcg ctcgtagttc cagacccatc tatgcttttc ctccagttgc
    11701 aaactgatga tagagtttga caatggcacg aaccaagatg gtacagaaga aataaacaga
    11761 aataaaacgt accacaagca aggaaaggac aaacggaagg gaaaaggcgt agtaacctaa
    11821 cttaatgtat tcatagacaa agctaacaag cgtaatccca atactattag cagttagaga
    11881 gagccaactt tcatagcgat tcttagttac gataaaacca aattcacttc ccaaaccttg
    11941 aacaaagcca gacaaaagag ctcctagacc aaattggcta ccataaagga cttcagcaag
    12001 cgcagctagc acttctccaa tcgttgcact tccgactctc ggaacaaaga tggcagcaat
    12061 gggcgcagcc atacaccaga gaccgaagag gatttcattg gcaaaggcct gcaaaccaag
    12121 aggtgttaag agtagactga gaatattata cacatatcct gaaccaacga aaaccccacc
    12181 aaaaaagata gacaagaaag caagcaagat aacatctttt aactgccatt ttttcaacat
    12241 aaaaaactcc tttttttaaa gaaaagtggg gcactcaaga agaccgacct aaatactttg
    12301 tatagcagac tgaatttaga acagtacaca agaacactaa aatatttcta gaaattaatt
    12361 tgaattttct aattgatttg ttcgcatctt atttcaatct actatatcat cttcatccag
    12421 tttcgtaaaa gaaaaaactc taattacaga tacaaattag agttcagctt acaagattag
    12481 acagttcttt tcgacatacg aaaaaaacat ttcacatttc ccttcgccag tcttaactgt
    12541 atcaggttca atgggtatca tctcagccta aagcacccca aatgtcttta ttatttaatt
    12601 atgtgattat tataacacac attttatact agttcaagaa attgaactgg aaatacagcc
    12661 ttgcactcac aaagacagca gatctttctt ttgcaaaaaa caaatgacct gtttgatgaa
    12721 ttagccattc aagctgaatc tggacatagc tttttaaaaa aggaaaatcc tacttactta
    12781 gaatccaagg atagatatct attgttcact catttcccga acagtttttt ctatattttt
    12841 tgcatacgat attgccgaaa tgattgaaac gccatccata ttggtcttta taatgtcttt
    12901 aatatgtttc gtctgtatcc caccaattgc aactaaaggc atttgtggca atagttttct
    12961 catcaattca agaccttcat aacctatagt accaccagca tcatcctttg actgggtacc
    13021 aaatacaggc ccaacaccta cataatctac atattcaact tttgattgtt gaaattcttc
    13081 ttcgtttctt atagaaagac caattatttt atctggcatc aattttctaa tttcatcaac
    13141 accaatatca tcttgaccta catgtacgcc atcggcgtca atttccattg ctaaatctat
    13201 atcgtcatta acgataaatg gaacattgta ttttttacaa agttctttaa tttggatagc
    13261 tagctcaagt ttttctaagc cttctaaagc accctcacct ttttctcgaa attgaaataa
    13321 ggttatacca ccttttaagg cttcctcaac gactgtatat agattttttc cttggcaagt
    13381 agtcgttcca caaataaaat atagttttag taattcttta tgaaacatct tacttcactc
    13441 ttttgaattc ctttacatct tcatctgtaa tctcgtataa ggcatttata aattcaactt
    13501 taaatgtccc aggaagatgt ccatttggac gtttttctgc catttctcca gcgatattgt
    13561 aaaccaacat tgctgtttct aatgatttca attcttgacc tttttctagt ccgataaagc
    13621 ttgctactac agctcctaat aagcatcctg tcccaatgac tttcggcatc atagcactac
    13681 cattatgaat cattaccact tctccattaa cagcaatggc atccacttca cctgttacta
    13741 ctattggaat attgaacttc tcatttgctg ctagagcaat ttcgtcaata ttatctacgc
    13801 ccgcactatc tactccttta gatgccacat ctattcctac taaagaggca atctcgccag
    13861 catttcctct aatcgctgct agtttataat tgttgattag atcatctgct actttttttc
    13921 tatattctcc tgctccacag gctacaggat ctaaaactgc tgggacatta tatttctctg
    13981 caattttcag agcagcttgg tataatttcc aattttcatc tgtcaatgtt cctatgttta
    14041 ttaataaacc accagcatac tttaacaaat cctctaaatc tgctggaaac tcactcatgg
    14101 ctggtgaggc gcccagtgct actaatccat ttgctgtgaa attttttact acatcattgg
    14161 ttatacaaat gaccaatggt gctttttctt ttaataattt taaacttgtc atattgaaat
    14221 ccttcctttt cactttatac gatctactga tttcgattta tttctatctt tcgttaagaa
    14281 tttttttcat ttacattgaa tgatttatac tcaatgaaaa tcaaagagca aactaggagg
    14341 ctaaccgcag gttgctcaaa acactgtttt gaggttgtgg atagaactga cgtggtttga
    14401 agagattttc gaagagtctt acctcatcaa atttgtaaat atcatgagcc ttctctagac
    14461 atcgtaacca atatcaaaaa aagctaattc taaagcgact gcttgattcc agcgttgctg
    14521 aagttctgtc aaatcttctc gatttttatc gacacgattg agttcgtcaa ccagaaattg
    14581 aacccactct gcaaagaaag gacctctgtg gagattgatc cattccgaat gaatatagac
    14641 ttcaggtaaa gccaaatctt tagaacccca gtctaaatag agaccttctg caatgaccag
    14701 catgaccaaa agatgggcat agtctgatga agccaccgcc gaatacatta gatcctgaaa
    14761 ggcttttgtt acagggtgca aagtcacttc tagatagtca ttctctgcta cttttaactc
    14821 tttaaaagcc ttttggaaat aaccatcttc atctgcttca agaaagccta gttgcttggc
    14881 aaaacgaagc ttggattcaa gtttatctgc gtgagctacg caggcaccca gcatggataa
    14941 gaaggcatca aagaagtgat aatcttgaat cagatagtcc tttaagacct tattctcaat
    15001 tgtccccgca aaaagttcct taacaaaacg atgattgatt gcagcctgcc aatccttctg
    15061 actgcttttt aataattctc caacagtcaa acctggctga aatgcatagt cttgtgtttc
    15121 catatttact tctcctctct ttacttgtta gtaattaata aaacaccaag aaatatcaag
    15181 caaaatcgta attccacttg atccttttaa agcacatcga gagcatttgc agagagctaa
    15241 ctaaacaagc ctatccagtt tatataaaca aaaaactcca attacaatca agaattagag
    15301 ttgacttaca agattagatc gttcatttcg ccatacgaaa aaacgtttca catttccctt
    15361 cgccagtctt aactgtatca ggttcaatgg gtattatctc agcctaaagc accccaaatg
    15421 tctctattat ttaattactg aaccagtata gcaaaaaatg aaagccctag caagatattt
    15481 gaccgaaaaa tatctttata tataatatat tgaaactaga atagtacacc tctacttcta
    15541 aaacattgtt agaaatcgat ttgactgtcc tgattgattt gtcctattct tatttcattt
    15601 tactatagtt ttcgatagca atttattctt ccaatacacg aagaaaaacc tccacattca
    15661 gtggaggcaa tctgttttat caatacaatt ttaagtcacg agggtcaact gggaaggttg
    15721 ggttgtatgg attgtgacgg agcttaaagt gtttgacatc ttcaatggtc tgagctccag
    15781 acaattgcat aactgtcttc aattccgcat tcaagtgttc aaagacttga cgcacaccga
    15841 cactaccacc gagagccaag ccataaataa cagggcgacc aatagctacc aagtctgctc
    15901 ctgaagccaa ggctttaaag acgtgttgac cacgacgaac accagagtca aagacaatcg
    15961 gcacacgtct atcaactgct tctgccactt cttgaagcga gtcaaaggca gctggtccac
    16021 cgtcgatttg acgaccaccg tggttggtta cccagatacc agaagctcct gcagcaagtg
    16081 aacgttcaac gtcctcacgg cattgtggtc ccttgacata cacaggaaga ccagagtatt
    16141 cagcgataaa ttctacatcg cgtggagaca agcgttgttt agctgatttg taaacaaagt
    16201 ccattgattt accagcacct tctggcaggt attcttcaac aatcggcatg ccaactggga
    16261 agacaaaacc attacgctta tccacttcac gattcccccc tacagtagca tctgccgtca
    16321 agacaatcgc tttataacct tcagccttca cacggtccat gatgtggcgg ttgataccgt
    16381 catccttact aaagtaaaat tggaaccaat ggggtgtccc ttgaagggct tcagaaatct
    16441 ctggaaggtc aacagtagag taagagctgg ttgtataaag agaaccaaac tcatgcacac
    16501 cacgcgcagt cgccacttcc ccctgttcat ttgccaattt atgagccgca acaggcgcca
    16561 taatgattgg tgaagatagt ttttcacctg caaattcaat ctctgtactt ggattttcaa
    16621 catcgcaaag tgtatgagga acgatgagtt tgtggttaaa ggcgcggata ttctctctta
    16681 aagtgaaagt atcttccgcc ccactagcga tatagccaaa tgctgcttta ggaataactt
    16741 gttgcgccat tggctccaaa tcataggtat tgatgaagtc tacatgacct tctgcattgc
    16801 ttgttttgta tgacataaaa tgccctcctt gattaagtaa gcgtttgctt tttactacac
    16861 aactataata actctttttt caatcatttt caagagtttt gcttaaaaac catcttattt
    16921 tttcatacaa tatactagcc ctactttcct taaactctaa actttagtct atattaagtg
    16981 aatcgttgag attttttgct gccaggcatt tgaactactt ttttatttgc ggattctatc
    17041 tactaatact ataaaaaaac aagtgaataa gacaccagaa catcctctaa taggacctat
    17101 ggacttatat cagtcccata tatactgttt aagcaagata ctatcctagt tgacgctaac
    17161 ttcctatccc acttattaat tttttattta tagtgaatct gaacaaatca attggggaat
    17221 ccaagtcaat ttctagtact ttttgaacag tttcagcgta ctatcgtaaa atgaaataaa
    17281 acatgcacaa attgcttagg gaatttaaac caatttctaa caatgtctta gaaatcaaag
    17341 tgtactattt caacttcaat atactacact tcattttctc cttaaattca gtctcttttt
    17401 gaatcaaaaa atcccctggt aagagccaga ggataagaat ttatttcatt gttgggaaga
    17461 gcaatacatc acggatagtt gttgtatcag tgaggagcat gcagagacgg tcgataccga
    17521 ttcccaaacc acctgttggt ggcataccgt attcaagagc ttcaatgtag tcatagtcga
    17581 tgcctgtcgc ttcatcatca ccaagttctt tggctttagc ttgggcttca aaacggctaa
    17641 gttggtcgat tgggtcgttc aactcagtaa aggcattacc gtactcctta gtcatgataa
    17701 agagctcgaa acggtcagta aagcgttggt cttcaggatt tttcttagcg agtggagata
    17761 cagctactgg atgtccatag acaaaggttg gttggattaa agtttcttca acaaactctt
    17821 caaagaaggc attgatgatg tgaccaacct cagtgtagtg tttctcaact ggaactttct
    17881 tctcagcagc gatagtttta gcttcttcca aagtcatgtc ttgccagaaa tcgacaccag
    17941 taatttctct gatagcatcc accatatgaa cacgcttaaa tggttcgtta atcttgattt
    18001 cagtaccttg gtagttgact gggccatcac ctttgactga tttagcagcg tgttggataa
    18061 tgccttcagt caagtccatg atgtcttgga agtctgcata agcttggtaa acttcgatag
    18121 aagtgaactc agggttatga gtagcgtcca ttccttcgtt acggaagata cggccaattt
    18181 catagacacg ttccatacca cccacgataa ggcgtttcaa gtgaagctca gtcgcgatac
    18241 gaagcaccat gtcaatgttt tgggcattgt ggtgggtgat aaatggacgg gcagcagcac
    18301 caccggcttc attatgaaga acaggtgttt ccacttcaag gaatcctttt tggtcaaggt
    18361 aacgacggat ttcagagatg atttttgaac gagtgacaaa gcgttcaaag ctttcacgat
    18421 tagaaatcaa gtcaaggtaa cgtttacggt aaattgtttc aacgtctgtc aaaccatgga
    18481 atttctcagg aagaggacga agagccttag acaagtgtgt gatgtgggtt gccttgatag
    18541 agagttctcc catatccgta cgcatcactt caccttcgac accaaggaag tcaccaaggt
    18601 ctgctttttt gaagatttcg tagttttctt caccgacagc atccttacga acgtagatct
    18661 gaatctggcc ttcgcggtct tgaaggtggg caaaaccaac ttttccttta ccacgtttgg
    18721 ttatcaagcg tcctgcgata gtagctgttt cgtttttatc gtgtaattgt tctttatcga
    18781 ggttggcata tttatctttt aattcttgtg aatttgcagt acgttcaaaa cgttttccga
    18841 aaggatcgat tccttgttcg cggagcgcag ccattttttc acggcgaacg atctgctggt
    18901 catttagttc ttccatatgt tctgtagaca tgggatcctc ctagttttac tcaaaattga
    18961 atacgatgag tcattttttg cgatactccc attttatcat aaataagcaa gaaattcacg
    19021 gataatcttt aaaaactaaa aagaacctga cgctaaaatc actggaaaga agtgaaagta
    19081 tctcccgccc cactagcgat atagccaaat gctgctttag gaataacttg ttgcgccatt
    19141 ggctccaaat cataggtatt gatgaaatct acatgacctt ctgcattgct tgttttgtat
    19201 gacataaaat gtcctcctta ataagtaagc gtttactttg tgtattacaa aaatatctta
    19261 actctttttc aaaactttta aaatattttg tttggaaatt tcagaaattt tatgtctatg
    19321 ataaaaatcc ttataacggc aataaaaaat agatattatc caaagaagat tttaagtgct
    19381 acaataactg tattatttct agatgggagg ttctattttt ggattgatcc attgttgaac
    19441 aatatctacc actatatcaa aaggcattct ttctgacctt gcatattgca gtttggggaa
    19501 ttttgggatc ctttctgctc ggtttaatcg ttagtatcat ccgacattat cgaatccttg
    19561 ttttggcgca agtagcgaca gcctacattg aattgtcacg taatacgccc cttttgattc
    19621 aactcttctt tctctacttc ggtcttcccc gaatcgggat tgtcctatct tcagaagtct
    19681 gtgcaacgct tgggcttgtc tttttaggag gctcctatat ggcagaatct ttccgaagtg
    19741 ggctggaagc catcagtcaa acccagcagg agattggcct cgctattggt ctgacacctc
    19801 tacaggtctt ttactatgtg gttcttccgc aagcaacagc ggtggcactc ccctccttta
    19861 gtgccaatgt cattttcctt atcaaggaaa cctctgtttt ctcagcagtg gctttggccg
    19921 acctcatgta cgtcgccaag gatttgattg gtctctacta tgagacagac attgcgctag
    19981 ctatgttggt agttgcttat ctgatcatgc tgctacccat ctcactggtc tttagctgga
    20041 tagaaaggag gctccgccat gcaggattcg ggaatccaag tactctttca aggaaataat
    20101 ctcctgagaa tcttacaggg attgggcgtt acgattgaga tatccatcct gtctgtcctc
    20161 ttatccatga tgttcggaac agtcatggga atcatcatga cctcccattc tagaatcata
    20221 cgatttttaa cacgattgta tctggacttt acccgtatca tgccccagct ggtgctactc
    20281 ttcatcgttt actttggctt agctcgaaac tttaatatca atatctcagg tgagacttca
    20341 gctattatcg tttttaccct ctggggagca gctgaaatgg gagacttggt acgtggagct
    20401 atcacttctc tccctaaaca tcagtttgaa agtggacagg cactcggctt gactaatgtt
    20461 caactttact accacatcat catcccacaa gtcttaagaa gactgctacc gcaggctatc
    20521 aatcttgtca ctcggatgat taaaaccact tcattagttg ttttgattgg ggttgtggaa
    20581 gtgaccaaag ttggacaaca aatcatcgat agcaatcgcc tgaccatccc aactgcttca
    20641 ttttggattt atggaaccat tctagtctta tatttcgcag tttgctaccc tatttccaaa
    20701 ctatccactc acttagaaaa acattggaga aactaaatgt ctgaaactat cttagaaatc
    20761 aaggaactaa aaaaatcctt cggagacaat cccatcctcc aaggactttc tctagaaatc
    20821 aaaaaaggga agttgttgtc atcctagggc catctggttg tgggaaaagt accctccttc
    20881 gttgcctcaa cggcttagaa agtattcaag gtggagatat tcttctggat ggtcagtcta
    20941 tcgttgaaaa taaaaaagat tttcacctag ttcgccaaaa gattggcatg gtctttcaaa
    21001 gttatgaact ctttccccat ctggatgtct tacaaaacct catcctaggc cctatcaaag
    21061 ctcaaggaag ggacaagaaa gaagtaacgg aagaagcttt gcaattacta gagcgtgtcg
    21121 gtttgctgga taaacaacat agctttgccc gtcaattatc tggtggacag aagcaacgtg
    21181 ttgcaattgt ccgtgccctc ctaatgcatc cagaaatcat cctttttgac gaggtgactg
    21241 cttcgctgga tccagaaatg gtgcgtgagg tgctggaact tatcaatgat ttggcccaag
    21301 aaggccgtac catgatttta gtaacccacg aaatgcagtt tgcccaagcc attgctgacc
    21361 ggattatctt cctcgaccaa gggaaaatcg ctgaagaagg aacagctcaa gccttcttta
    21421 ccaatccgca aaccaaacga gcccaggaat ttttaaacgt ctttgacttt agccaattcg
    21481 gctcatatct ataaaggaga ttcttatgaa actattcaaa ccactcttaa ctgttttagc
    21541 acttgccttt gcccttatct ttatcactgc ttgtagctca ggtggaaacg ctggttcatc
    21601 ctctggaaaa acaactgcca aagctcgcac tatcgatgaa atcaaaaaaa aagcggtgaa
    21661 ctgcgaatcg ccgtgtttgg agataaaaaa ccgtttggct acgttgacaa tgatggttct
    21721 taccaaggct acgatattga actagggaac caactagctc aagaccttgg tgtcaaggtt
    21781 aaatacattt cagtcgatgc tgccaaccgt gcggaatact tgatttcaaa caaggtagat
    21841 attactcttg ctaactttac agtaactgac gaacgtaaga aacaagttga ttttgccctt
    21901 ccatatatga aagtttctct gggtgtcgta tcacctaaga ctggtctcat tacagacgtc
    21961 aaacaacttg aaggtaaaac cttaattgtc acaaaaggaa cgactgctga gacttatttt
    22021 gaaaagaatc atccagaaat caaactccaa aaatacgacc aatacagtga ctcttaccaa
    22081 gctcttcttg acggacgtgg agatgccttt tcaactgaca atacggaagt tctagcttgg
    22141 gcgcttgaaa ataaaggatt tgaagtagga attacttccc tcggtgatcc cgataccatt
    22201 gcggcagcag ttcaaaaagg caaccaagaa ttgctagact tcatcaataa agatattgaa
    22261 aaattagcaa ggaaaacttc ttccacaagg cctatgaaaa aacacttcac ccaacctacg
    22321 gtgacgctgc taaagcagat gacctggttg ttgaaggtgg tcattaactc ttaaaaggga
    22381 ctggatttta agctccaatc cctttttaag attttaccta taacatcctg agtctatcta
    22441 agatgttcaa tctgaacaca gtgtacatac tttatcttct attgcatata ctttatcaca
    22501 taagatacga atatcctctt cactatgact agcaatcaaa attgttgtcc ctttttcact
    22561 agagagcttt ctaaacaatg ttctcatatt ttctacactt gatttatcca aggcattcat
    22621 aggttcatct agtaaaagaa tagagggatt ctccatgatt gcttgagcaa tccctagctt
    22681 tttcctcata cctagcgaat aagttttaac tttctggtct ttttgctcat atagaccaac
    22741 tattttcagt gtatcattga tttcctgatt accaactact cctcgtatgc ttgccaaata
    22801 ttgtaaattc ttaaagccac tataataatt tataaaacca ggttcttcaa tcaaagctcc
    22861 caaattagct ggaatttttc tctcaggaac aatattttcc ccattgatta acacttctcc
    22921 ataagacgga ctatataaac cagctattaa tttaaacaat acacttttcc ctgagccatt
    22981 cgcaccagta attcctataa tttccccctg tttacaacta aagttaaggt tttgaaaaac
    23041 acatgtcttt tttaatttca actcaatatt ttttaatata attatttcat tcattctata
    23101 aacctcctct tttgacgagt gaaatagaaa atgctttgaa aaagaaagac taaaaatagc
    23161 aactgaagaa acaaatctcc ccctacatcc ccattccctc gattcaaaat ataaaataga
    23221 taattagttc gatttcctac aaatagacca ccaaacacaa tcatgagtaa aaagaaacta
    23281 acgcaagcaa agttcatttg tacattcgct cctagtgcgt ataacataaa gcaaaacaag
    23341 actaacacac aagcattcaa agaatcaact ataaacaaaa ctcctatatc ccagtttggt
    23401 aactgtaaca taaattgaat cactagaact tttaccatga ttaaaatgag tccataaaga
    23461 aaacaggtcc aaatctgata cctaatccag agcttaatag aagaaaatcg aatcacttcc
    23521 ataaagaaat cggatgctct tctacgatat acaactgcta gaaaaaatgt atgaataata
    23581 aaccaatgaa gcaaccatat agataagact aaaaaagagt tttgactcag attaggccct
    23641 tttaaaattt ctataacaag tctatcattt ccttctaacc aataccataa tcctaaacaa
    23701 atcaatatcc aaaaaagaac ataaccccaa aagtacttgg tatagattat cttattcaac
    23761 ctccacatgt gactacttaa ctttcccatt tccaactttt acactctcct ccagtttcta
    23821 tgaacagaaa atacagtcaa tggaattatg atagatagta atgtaagcca ataaatcaat
    23881 gcatacggat tggaatttac catatactga aaaattggca ataatccaat tatcccattg
    23941 ttcaactgat aaatccagaa taaggattct acaaataaaa aagtaaacag aaatactaag
    24001 ctcatgtttg attttttaaa ccaagaaaaa ctgctaatag taagtaagga taaaaagaaa
    24061 tagtatgcta tataagagaa aaaaaatcct ataaagaaac tagcattgtt tgcaatactt
    24121 ataccataaa attctcttaa aaaatcaacc tcctttatct ccaaagagaa gctaaaacca
    24181 ttactaaatg caattagaaa aatcaataaa aataaagtcg ccgtccaaat ccccgtacta
    24241 agagctgcta atttgaaact aaaactggta aagtgcttaa ttgatttcag acgaatgcga
    24301 cactccaacc tattaaaata gttattcatc aaataaaaaa agaacaatat atatgtgaac
    24361 ggaaagcaat atactccagt cgtcatatct tgaagtaaaa ctaaaatcca ttctaataca
    24421 tttggatgga ttgaatattg gcgacagcgc aataaatata ctgtactaga taaaacacag
    24481 gatagcagta atataaaata aaccaatact gataaaaaat cttttttgta aaattgaaca
    24541 aattgtttca ttatacatag tcctctgaat gtagaaaaaa tgtaccataa acaaccaaac
    24601 aactaacaaa taaaataaaa gcaagatgcc cactaactaa ggaaagactg atatctttct
    24661 gatatcccaa agctaatgtt gtcacaggtt ctaagtaaga tagccctaaa atagcccaaa
    24721 aaataccacc aaccatcata taggcaactg ggatgaaaat agctcctatt tttttcttca
    24781 ctagcaaagc actagctagt ccaaaaatag agaacacagc gccccaaact ccataccaga
    24841 gagtcgtcac aagactatag agcaactgat tagaatcaaa taattctttt aaggcaccac
    24901 tataatctcc aatataaatt tcctgataag gagtcactaa aagattaatt cctaataata
    24961 ataaataggg gagaaaaaag actagaaaag aagaaataat tgcagtacta cctacaatag
    25021 ccagatactt ctttttagaa attcggcaca attgtgctgt tagaaaatga ctctcagcat
    25081 cctctattat ctgactagaa tagggcagtg tacagataag tgcagctact aggctaatcg
    25141 gtgaaaatcc tcgaatagaa gaagcggcaa aaaaaatcga taaaccttca attttataaa
    25201 taccattgaa agcaaggaaa tttcctaaac tcatgcaaag aagggtcaaa aataaagaca
    25261 tataaaatcg aggtgattga acgactcgta caagattaca aatgaaaaat tccatcctta
    25321 ctcctcctta taataaaaat agggtgtagc attctttttt catgctacac ccacaatcaa
    25381 ccatctttaa ggcttactct gacaagtaag ttaataagaa tctggactcc aagaacctga
    25441 agtatgaatt cttacatgat ttccaaattg tggcgccata gctaatctag taccagaacc
    25501 aatataattg tcaccacctc cattatagta catgacaatc ctagagccag accccaatga
    25561 atataccggg gtaatatctg acccactata ggcgctacga atagaggtat ttaacctttt
    25621 accgccacca gtgctgtcac tattattaat tccagcagag gcgttttctt tctcaagctc
    25681 actagttgta tccgaacccc aacgcggcaa cgttaaatca taatttccaa tctgtctagc
    25741 taaaactgta gggagaaaca aactagatgc aattgtaact acgcaaaaaa ggaatatatt
    25801 tttcttcttt tcatgacatc gtcctcttaa gaagtgataa acaagatagt tgattgatca
    25861 atttgataca tattacattt tcattatatc aataaaagaa agcgttgtca attattttat
    25921 ttaaaatatt gtcatatttt aaataaaatg gtaaaagaga ctcggtagcc tcgtctctct
    25981 ttatcttact gacctaacct tcttgccaat tttcttggtc ttctttaaag cgttttagaa
    26041 gatcaaggcc ctctggcgtg atgtaacctt cttcttgggc tagatggata agctctctat
    26101 agtttgaaag cgtcacaagt ttaacaccag catctgcaaa gttcttatct gcttttggca
    26161 attggtagct gaaaatcgct acaactccaa gtacatctgc tccttctcgc ttggctgctg
    26221 ctacagcttc aagaactgaa ccacccgttg aaataaggtc ttcaaccact accatttttt
    26281 gaccttgagc tacgcgacct tcgatttgat taccagctcc gtggtctttt ggtttgctac
    26341 ggatgtaggc aaaaggcaag tccatcttat cagcaataat ggctccgtgt ggaatccctg
    26401 ctgttgcagt tcctgcaatc acttctactt caggaaaggc ttctttaata gcttccacaa
    26461 aaccattttc aattagggta cgagtttctg gataggctag tgtcacacga ttatcagtgt
    26521 aaatcggtga cttgatacca gatgcccaag tgaagggttc ctctggtttg aggtaaacgg
    26581 cttggatttt caagaggtgg ctagcgatat ctttagcaag tgtcatggta ttctcctttt
    26641 atttttctaa tctagttctt taattccagt tctgtgtcca ttcatccttg atggcatgat
    26701 aagctgcaac aggatcctca gcttgggtaa tgggacgtcc cactacgata tagtcactgc
    26761 cgatttgata ggcatcagca ggtgtcatga ctcgtttttg atctccaact gcaacaccag
    26821 ctggacgaat ccctggtgtc agacagataa aatctggatt ggtagcctgc ttgatgactt
    26881 gtacttcctg agccgagcaa acaacaccat ccaagccagc ttcagctgtc ttcttggcat
    26941 agtgaatcac agactcttgc agactggttt ggatattttg aaactcctgc atctgagctt
    27001 ctgacgttga tgtgagctga gttacagcga tcaatttggc ttgactccca agaccttcac
    27061 gcgccgcctt catcatctct acaccaccag ccgcatggac attagtcata tcgacaccaa
    27121 gctgagacaa gaccttcatg gctgacttga ctgtattagg aatgtcatga agtttgagat
    27181 ccaaaaagac actatgaccc aaacctttta agtaggacac aatctcaggc cccgctgcgt
    27241 aataaagctc catccctacc ttgagataaa ggctttcttc tgctgggaaa agagctaaaa
    27301 attccttgac cgcctcaaaa ctaggaaaat caagagcaat gattggacga tgttctcgca
    27361 taggtttctc cttttacctt tactagtgag agagtctggc caacagaagc cacgaaaaaa
    27421 ggaacctgcc aacagcaagg ttccacgaaa aatgggtagt ctccaccctt tcaccgtcta
    27481 accttagctg cctctctgga ctgctttaaa ggttttctat tattctatta tttctactag
    27541 cacttgtcaa gtaaaaactt agtcacgtat gtgttgactg ctattgaaca cctcacaaga
    27601 ctctttccaa aagaatagtt aaagactttc acttaggaca gagaaaaaga gtttgcttgt
    27661 taccctttaa ttgaacaaat gggaattctg ttttattttg cggatgccta ttcatcttgg
    27721 caaaggggaa gtaatgagaa tgcgaatgga cttcttcgtg agtattttct taaaccgatt
    27781 tggcaacaat taccgaaaaa atccttaatg gtgctttgct agcttattaa tcaccgtccc
    27841 caaaaatact tggattacaa gacaggtttt gaagcactta tagaggaaat ttaaaaatgt
    27901 tgcatttttt attgcaattt atcagttatc ttatcaccca aaacttctgc aattagtatg
    27961 agcactattg ttatttttct tttttcgtac actcaaatca aaatatagca ataagactat
    28021 tctgtagaat tgctgtcaaa aagatcagtt catttttcct tcccacttgt gtttataatc
    28081 attaaaataa ctcaattaag aaattttctt tttcctaata gttatcgtaa ttaaagttaa
    28141 tagaagaaca atccaaataa gtagtgttag attaggaatt agagttttat tccatgaaaa
    28201 tccctcccat tttgtgaaaa acttagtaaa cagtcccata aaactataat ctgttatctt
    28261 cgcaactgtc ttatccaaac cagatagcat cggtaagaaa gcaactaaaa tcatagcagg
    28321 aagactgata acctgagcta ctacttggct cttcgcggtt aaacctatca ataaatagaa
    28381 taaaatgatg gataaagagg ttagaagaac gattgtaata taattaaaag tatgtacaat
    28441 tgtaactcct aaaataagag gagtagttcc cataatcaca aaagttagca aaaaaggaag
    28501 aaacatcgtt gataaaatgt attcggatcc tttaacacca ctcaacagaa gagtttgtaa
    28561 attgtacttt tctttttctt cagacaagat aatagttata ggacttccaa cagccaaagc
    28621 caaagaaaaa ggtaaacaca tcatcaaaag aactaatgcc tgttgatcgt tgaccttccc
    28681 ctgtgtttcc ataagatatt tataaaaata tgtgaaagca aaaggcacta aaacttgcaa
    28741 taaaatactc ttattggaaa ggataatttg acaacgcaac cataccaaag ccagaaaccg
    28801 tttaagcatt tagctttcct cctgttaatg tgataaaaat atcttctaaa gtaggctcac
    28861 atgaatgaat tgaaaaaata ttttccagat cagcctgaga tacctgttct agtgatgtaa
    28921 aatcaaaagt tatctgattc ccattataat ctgtaacctt aatcttttta tctttattat
    28981 atctttgaat gagttcagaa ggagctcctt gctcaactaa tttcccttta tttaataagg
    29041 caacataatc acataaaaga gttgcttcat tcatatcatg agtcgttaga aaaatcgttg
    29101 tccctgctgt tttcaattct aaaattaact catgaattgt tcgagaagtt gtgggatcta
    29161 gacctgaggt cggttcatcc agaaagagta cagcgggttt gttgataaga gctcgtgcta
    29221 aaagcattcg ttgcctcatt ccagtggata attttcctgc taccatcttg cgactatcat
    29281 ataatcctac tcgctttaac aaattatcaa cacgtgattt actaatatta taaaatttac
    29341 tataaaaaag aagattgtta tacagagaca ttttctcata aaatccactt gtatcgctaa
    29401 ccaatccaat tctctttaat tcaccgcttg ttaaattttg agatttttgt cccaaaataa
    29461 tagattgtcc tttatcggca aggaactgcc cagtcagaat attaatcgtt gtggtctttc
    29521 cagaaccaga tggtcctaaa aatctaacct tctttaacag tgaagcttat attatttaaa
    29581 gctattttat caccaaaact ttttgataaa tggctaactt caatcatact cattgcacct
    29641 cctttatatt ctacattttt acttaacatc tatttactta tctttatcaa ataaacgtct
    29701 taaaaaaaac aataacatta agcatataac cgttagcaag attgtttcaa tattattgat
    29761 aatacgatac attctcaagc agtataaaat aattatatat atgcaaatgc tcattatacc
    29821 tattttttta aacatactaa gcctccttgc taaataataa agttatataa taactaagac
    29881 acactatacc taacataata aatatccact ggtaactgaa taaatgttct aaaattaaca
    29941 agcaaaaata aaatctcaaa cgatgaaaaa agccatacta tattttccaa tgatgtttga
    30001 atatttttat tgtagtaagc ataatatata gcaaaaataa tacccaagaa caatactatt
    30061 aattgtgttt ctataacagt gaactgccca atagcagata aaaaagctac tcctcctgat
    30121 aataagcaaa aacaaactga acgaataaat gttttcgctc taatattgtt atctttcact
    30181 ttattatttt tttacaaatt ggacattctc cgttttccag aacatatttt tcttgactta
    30241 gagcatgatt tctcatatta taaacgtaag cgttatctat taggatttca ttataacatc
    30301 ccagaaatat tttaattatt aaattagtca ttatccctcc caaaatagca ggcatctctg
    30361 gtgtagtcgg ccactttgtc ttatcagata aagtgtactt atttatatct ttgtttatat
    30421 tccgacaacc aaagcaagaa ccgatggtag ggatatatat tatcagtaat aagatagcat
    30481 ccattaaacc ctcctgatat gtaggatatc ttatgcgata cagcaaattg attgacaatt
    30541 tttataatat caatgggcgt atcaattgct ttaacgataa aatctatact cccatattcc
    30601 gcaacaattt tttctaattc ttctactgaa gaaactttaa tagaaatagg tactacctga
    30661 acatctgaat tatacttgtg tattttttca gaaagaacat taatcttctc cttaccaaca
    30721 tccgactctg tataaagaat ttgcctattt aaatttgatg gttctattat atcgtaatca
    30781 gcgacaataa gtttcctcac tccatacata cttagactta gagatatata acatcctaag
    30841 gctcctgctc ctaatactaa tactgtttta ttctgtattt tattatactc ttcattataa
    30901 aataacgaat agtaaccttt agttctagaa tatctactat caatatctat ctcatccgaa
    30961 attaaaattt gttcatttaa tagttcaaat gttagtttac tgcctaatac ttcttctatc
    31021 tctaatagtt ccttacaact attaaataga tcgttgataa attcttgcga aatttgaggt
    31081 tctatagcta tttcccgcat actccgacca cgcaaataca ttataccttc ttttttataa
    31141 gcaaaaacat aactatttac gtagaacata tttcgtcctt cctctcatat ataatataga
    31201 aagcagtata gaaacaacca cccctcctat actacgaaca ataatattag gtgtcaaaaa
    31261 ctgtaatagt tgactcaaag ggaaataaat aataacaaat gctattaaaa gttgaactat
    31321 atattgaaaa ttcaagttat tattgttaga attcaagtat cttaaaataa taccactatc
    31381 atactgaaaa aaaggaattg aattaataaa aatcatacct aagttaatga taaaaaataa
    31441 gagtccaagc aatttatacg atgtgaacaa taaaacaagt aaacctgtaa gtgataaaat
    31501 cgaatttgaa gcaattcctg ctaacataat tttcaaaaat tgttttttat tttttaagaa
    31561 ttgcacccca cttaaatcta caaaaaaaag ccaaattaaa caaaagtagc attattccac
    31621 aatttgggat ctcaatttga taattattag caattattgc atgactaaat tcatgtatcg
    31681 ttgcagacat aataacaaca agcaaccaaa ataaaagaat gtttagcgtt attggaaagt
    31741 tttggaaatt agtcaaaata tccgccctat aaatatacat aataaaacat tgcaaaataa
    31801 gagccaatgg gaaaatacca aataggattt tttcaaaatt cttattaaat cttttatagt
    31861 ttaatttttc agataatgtt atattaaagt cccaagatat tttaaaaata tttatctttt
    31921 ttcgtgattt catagaatct ataagtccca ttttactaag aacaatataa aatcttaaat
    31981 aatatttctt ccctactaac actaataagt ccgatatggt aaattcttga cctattagtt
    32041 gctctaacca tttttttcct gtttcccaac taatacatgt ttcttactag atggtatata
    32101 tagatgatac tgtccctcat aaggagtagg taatatctta atcttatcaa caattctcat
    32161 aacaaaccta acctttaata aataaaagag gggctaagta aaacatactc tagtccctca
    32221 gtccgcaatc aataaaataa tgactaattc tattaatctc ttgctgcaag actaatacgg
    32281 aaaattcaaa tgactgtcta aaatgaaatt gaaaaagctt gatgttagta aatgaacaaa
    32341 cttcaacaac cagcaagagc aaggattgct aaaccaaatc cgatacctgt tgcaagtcca
    32401 gctgaaaaat cactaactgg tactgaaatt tcttcaattt cctcaaataa aaagttatct
    32461 tgcatgatta tcactcccta tctttttaac aacaggctat tccaattaag agaactaccc
    32521 cagttccaag taaaactccc ccaaaaattc accatctgta ggggctacga tttcttcaat
    32581 ttcttcaaat aagaatgctt catctgacat atgtgttacc ttcttcataa aaaattattt
    32641 tgtaatcgat tacattgcaa atgtaacata aagaaaaaca gatgtcaaat attaaacgta
    32701 agaacatggt cactaaagaa ctataagaga aaaggtaaac ctagcgacgc gatgagcgct
    32761 gggtcgtttg atttcgattg ctctcttcct cttgtttttt ctgttcttct tcctgttttt
    32821 tctcggcttc cttggcctct tgtttggctt tttcctcagc ctccataatt aatttatccg
    32881 ccacagtgta actgtaaatt ccagcttcca tgtcgaccac actcggttct gacaattgtg
    32941 gcttaatctt actgtaatat ggcagtttct tactcatttc agatagagga accaagactt
    33001 cgtccgaatc attcatggtc aatcgaatta aatcggatgt caccttgctt ggggctaatt
    33061 ccaccttttg gatagccgcc ttgagttctg ggctaatttg agcaagttct gagacaaaaa
    33121 ccttgatttg ttcactatca ttaaagagaa ctgataaata agtttctggt aaactgttca
    33181 gactcacaga actagtctca agctgaccac tggaaagaat aggataatga ttttcaccag
    33241 aaatatagta ggccacaata tcatattcct tgaccttaat agtgaactta gttggaaatt
    33301 gatagacaag ttgagctgat tcaacccaat agttagactt aatctgcttt tcatattttg
    33361 ccttgtctag cagaaggtta atcgtataat ccgaatcctg aatgcctgaa gcctgtcgaa
    33421 tatcatcagc tgtagtttgc accgttccct caacacgaat atctttcatg gtcgcataag
    33481 gactgagcaa gtaggcagag acaatcaata aaagcagact tggaaataaa atcgtgaagg
    33541 ctcgcaagat atggatacca ggaatctttg ctttggctgg tttttccttt gtagcctttt
    33601 tagaaagctt tttatcctgt tcctccttct ctttagactc tggttcttct ttctcttctt
    33661 tctctttgtc agcctctgag gatgctactt tttcttcaga ctcttcctta gctgattctg
    33721 aatcttcctg gtctgtttca ctctcctggt cctgtttgtc ctctgacttc tcagattctt
    33781 ctcccattcg agcttgtctt tccttttcct tctcctcagc tagagccgcc tcttcttcag
    33841 ccttcttttt tagatattct tggtttcgtt tctgccattc tgataactct ttcaattctt
    33901 cgaggatttc tttgtcctca tttttcttat cttttgacat ttactttcct tatgataaat
    33961 cttttttcaa caattgataa aaatctgcta gagatttcaa ttccttagaa gccttcatct
    34021 tagcttggta atcttccttg tgacttagta agtgagaaag cttctcttcc aaactatcca
    34081 aggtcaaatc gctttcttga aggtcttctg catagccttt ttttacaaag taagctgcat
    34141 tttcaagctg gtcaccacga ctagcttcac gaccaagcgg cacaatgaca tgcaattttg
    34201 ctatcgccaa gagctcaaaa atcgtattgg caccacctcg tgtcacaaca atatcagcca
    34261 attccatcaa gggttgatag agatcggtca catagtcaac acgaaaaaga ttttggctca
    34321 actcattcag gctagaatct ccagttagat tgataatatt gtagcgctct gttagttctt
    34381 tcttatggtc tgtcaccaat tggttaaaga cacgagcacc tgcagaaccg ccaacaaaca
    34441 atacagtcgg caatttatga ttaaagtggc tttgaatatc caccaattca tctggttctg
    34501 gatttttttg atctgaaacc ttggccactg ctcccacatg ctcaacctta gacaaactcg
    34561 aagcttgctc aaaggttgaa tacatcttag tcgcaaattt ataggcgatt ttattggcca
    34621 agcccataga caggtcagat tcgtgaataa agacaggcac tcctgacaca cgcgcagcga
    34681 taacaggcgg tactgagaca aagcccccct ttgaaaaaag ggtctgtgga cgaagtcgca
    34741 acatgataaa gagcgattgg acgattcccc agcaaacttt gaagacgtcc agcatatttt
    34801 gccaagagaa atagcgacgc aattttccag tcgcaataga atggaaggtg acatccaaac
    34861 ctgacttaag gatttcttgg tgttcgatac cacgcttgtc cccgatatag tggacttccc
    34921 aaccatcttc gatgaacttg ggcattaaca aaagattgag ggtaacgtgt ccaaccgtcc
    34981 ccccacctgt aaagacaatt tttttcatat tattctttta actccgctac tgtgtcgata
    35041 aagaggtcgc cacgtacttc aaagttagca tacatatccc agctggcatt ggcaggacta
    35101 agaagaacca catctccttg agtcgcaagc tcataggcct tgcgggtcgc atctgcaata
    35161 tctgtcgcct ccacataagc gacaccagcc ttgtctgctg cccgtttgac acgttctgca
    35221 gattgaccca ggatgaccat cttcttgagt ccagtaatgt ctggcaccaa ttcgtcaaac
    35281 tcattgccac ggtccaaacc acctgcaatc aagacgacct tgctgttatc aaatcctgac
    35341 aaggcttttt gagtagccaa gatattagtt gatttactgt cgttatagaa tttaacaccc
    35401 ttgatgtcat ccacaaactg gagacggtgt ttgacaccac cgaaggctga aagagtttcc
    35461 ttgatggttt gattgtccac accacgaagc ttggctacag caatagtcgc aagggcattt
    35521 tccacattgt ggctacctgg aacaccgatt tcattcgctg ccatgactac ttcaccacgg
    35581 aagtagagtt gaccatcttc cagataagct ccatcaacct tttcaagtgt tgaaaatggt
    35641 acaacagtgg cttctgtctt ggaagtcaag tcttttgcca agtcttgatt aaagttcaag
    35701 acaaggaaat cagctgctgt catcttgttc tggatattcc acttggctgc tacatattcc
    35761 gaaaatgacc catggtagtc gatatgagtt ggcatgaggt tggtaataac cgcaatctct
    35821 ggatggaatt cttgaacacc catgagttgg aaagaagaaa gttccataac aagcgtgtcc
    35881 ttatctgatg ctatttgagc aacctgacta gctggatagc cgatattccc tgataaaaga
    35941 ccatgttgcc cagcagcagt caaaacttcc ccaatcatag tcgttgtggt tgtcttaccg
    36001 ttcgatcctg tgataccaat aatcggtgct tctgaaatca aataagccaa ttccacctca
    36061 gtcaagactg gaattccctt ggccaaagcc ttttcaatca tgggattgtt gtaggggata
    36121 cctggatttt tcaccataag ggcaaactct tcatccaaga gttccaaagg atggccacct
    36181 gtaatgacct tgatcccttc ttccagcaaa ctttgggcag ctggattgtc ctcgaaaggt
    36241 ttcccatcat ttactgtcac aatggcacct agcttgtcca acaaacgagc tgcagattca
    36301 ccagacttgg ccaaacctaa aacaaggact ttcttatttt taaattgatc tattactttc
    36361 atgtctcgaa ctccatttct actcctacta ttttaccatt tttatggaaa taaaaaagcc
    36421 acaaagtgtg tttgtgactc tttcttctaa ctgaatctta ccatatcatc tatgtgataa
    36481 atcggtaact cgaatgacct gatccacttg ttcccaaata agaggattgt gggtcgcaat
    36541 aataatggtc cgattcggat tttttaaaga ttctaggatg gaaagtaatt cctcagagtt
    36601 tttggggtct aaggaagtgg ttggttcatc tgcgaggatc aaaggtggat cctttaaaat
    36661 tatcttcgct aatgcaacac gttgtgcttc tcctcctgat aactcaaata taggttgctt
    36721 caaatccaaa taagagaggt ttacacagtt tagagcttgt ttcatcaaag agattttctc
    36781 tttttccttc aactttttac caactaaacc cagattgaga ttctctttga cggtttggct
    36841 ttcaattaag ccaaaatctt gaaataagta tcccaagtaa tctctaaaga aaacagaagg
    36901 cttgatgtcc ttaagagaag taccatcata gatgatttgt cctttgtcat atggctctaa
    36961 tcgtccaatc atattcaaga atgttgtctt accacagcca cttgtaccga ttaaggcata
    37021 aattttccca ccttcaaaat gaagatttgt atctgaaaat agctgacggc ttccaaattt
    37081 tttagatata ttctttagtt caatcatcct attttccttt cataattgtc atagaaacac
    37141 gagattcttt ctgcgcttga cggtaaagcg tcagaactgc actagctaga aagactaata
    37201 aagtgagcaa gccaatcacc aagtctcgac tgcttaaaat aaagagacta gcaccaaata
    37261 caaaactggc aaattgacta accatatact gagcatgtgt ttcaaaaaat cgtaaacctg
    37321 aaattcgttt aatcaaaata tctcggcgga attgctcgaa atatagaaga ttgacagaat
    37381 aaaatagtaa taaggaacta gctatcccca caatagctcc taagattaaa gttgctgttt
    37441 cagtttgaac ttcattataa cgagttagat aaacacttct tccttcttta agataggata
    37501 cttgctcata aattccagct ttcttcaaga gttctagccc actctcatat cctttgataa
    37561 agagttgttt tccagcattg atagaccaac tagataagga tataaaacta tcacctgtag
    37621 aagtcggcgt gaataccact aaaatcggat cagtcaaata ctgagtagat acgggattct
    37681 caccgttatt ataaacaaac cgcttttctc ccattgaaag ataactaacg tgcgctttca
    37741 tctcataatc caaaggagca cttgcctcct caccagattt tccataataa ctcaatcttt
    37801 cttcaaaaac tttcttaagt tctgcttctc gagagcgcaa atgttctggg agcaagagga
    37861 taaactcacc tttttggaga tgggctaact tctgtttggt ctcagcatct accacgacct
    37921 tttccttgtc caaataactg ggactaacat agagcgtatt agcatctgga ctataggtat
    37981 ccagtgtctc tccctgttca ttttttcctt gtggattggc aaaatggagc agattatcct
    38041 ttacataaag agcttgttct tcttcgattg cttccttggc aaaggcatac cacttgctct
    38101 gattttctgt atcttttcct ctatcaccta agccaaaaga aatttgataa tagtctgctc
    38161 tatcctgcca tgcttgtttt gaaatttcaa gttctttcaa tcgttggtaa gacatcaaac
    38221 ctgtcttaac agcgtagcct actgtaaaga cagcaaccaa ctgacacaat agggttaaaa
    38281 tcatcaggcg tttaaggggt aatctcccct taataacggg aactaatgct ttgtaactca
    38341 aactcattag ataaagaagc attagtaaaa ttgaaatcgc caataaaaac aacagataga
    38401 aactaatccc aaaaccatag gtggctaaca agataggata aaacaaacct tgactaaaaa
    38461 gaacgactcc cccacctagg aaggaaagga gggctgatag aaggagccat ttgatatcag
    38521 tagataaaga atgccccatg atggataaga gagtctgacc agaaaagagt tttatacctg
    38581 ctgctctcat ttccttaatc cgagtgataa tcactaaagc aaagaaagat aagccaaata
    38641 ttgctaaact aattaaaata aggggattta gtaatattcg aaaagcaaga aaatagggcg
    38701 gtatctttcg gtcagcactt gctttataac ccaaatctcc taatttatcg gcaagctttt
    38761 ctttcgtcaa ggagcctgac aaaaggagat aactatttag cggatcacta cgttcacgac
    38821 tttcttggct agcttcttgg aattcttttg gtaaagttcc ctgaccataa gttgcataag
    38881 taaagtgagt cgtcccatcc ttactcggct ctacaattct tctagctatt aaactctgtt
    38941 ctgagtttgc aaaattctcc aattcctgtt caaatacctc acgcgtcggt tcctgagtat
    39001 cttttttgac acgaagtaaa gaaacggaat catagcttgc atataaatat tgtggcgcac
    39061 gtaagacaat aatccaagca aggaagaagc tgagaaaaaa agttgataat aatatgaata
    39121 gtttcttcat agtagactcc ttgtaaacaa aattccccct gtaatttctt acaaggggaa
    39181 cgatttaaat caatgaacga ttagtcataa tcacagtaaa atgctacttg ttctccccat
    39241 ttagtccaaa tccatgcata ggaggttttt ccagcagaag cttctccttt atctgaatga
    39301 ctattccatc tacttacaag agaagaataa tgatattttt taccatgata gtaatttgaa
    39361 aaagcccaac cacctcctga accttctcca tacgtccata ctcctccatc tggatattgt
    39421 acagcagctg atgcagctcc caataatgta aaacttgaaa taagagctag agcaagtaat
    39481 ctatgttttt tcgttttcat tttatttttt ctttcaaaaa aagcacacct tgagcaacaa
    39541 tgcaacaaaa taaaccctcc tctctctttt gttgaaaccg ctttcttatg tgataaaaat
    39601 atcattttta ttatttgttg tcaaggaaaa aatcgaattt tttagatatt ttactacatt
    39661 gcctctatga ataatattat atagtagttt tattttaaaa taatatgcaa ccagtactaa
    39721 ccaaatataa aatagatgcc attaacgaat tttattcaag tttttcccat tcatactatc
    39781 caagcaaaag agatgatgtt atagtacaaa acaattcaaa ctattgtaaa attcctagca
    39841 aaaaagagag ccaaaactct cttttttatc ttcttttact ttttttgact ggcatgagtg
    39901 taatgtctct aacactaaag taagctagga tcaacatggc tattgctagg aatatttctg
    39961 ttggtaattg aaaaattttc agaaaagata gaaccaataa aatcaagagt gccactaaaa
    40021 tacataccat agcgacgata ttgactgtcc ctttaatgct ttctggtgtc gcaaatacat
    40081 agagtaggag cagtaaaatt cctaggacta aatagaccat ctttctctct ttctagctct
    40141 tattcagctg attttttctt cttgttagct ttctcacgct ctgctttgtt aaggatttgt
    40201 ttacgcaaac ggatagactc aggcgttact tccatgtact catcgtcgtt caagaactca
    40261 agagactctt caagtgtcaa gatacgaggc gtcttgataa cagctgtttg gtccttagta
    40321 gctgaacgaa cgttggtcat ttgttttgcc ttcgtgatgt taactgtcaa gtcattttca
    40381 cgagagtttt caccgatgat cattccttca taaacctcag tacctgggtt gacaaagatc
    40441 gtaccacgtt cttcgataga catgattgag taagttgtag ccttaccagc atcgatagaa
    40501 acaagggcac cacggtgacg tccaccaatt tcccctggaa tcaatggcaa gtattggtcg
    40561 aaggtatggt tcatgatacc gtaaccacga gtcattgaca agaactcagt tgagtatcca
    40621 atcaaaccac gcgctggaac aaggaagacc aaacgagttt gaccattacc agttgaaatc
    40681 atatccaaca tttcaccttt acgttcagaa aggctttgga taacagaccc ttggtattct
    40741 tctggagtgt cgatttgtac acgttcaaat ggttcacatt taacaccgtc gatttctttt
    40801 acgataactt ctggacgaga tacttgaagt tcatagccct cacgacgcat tgtttcgata
    40861 aggattgaca agtgcaattc tccacgtcct gaaacagtcc atttatctgg tgaatcagtt
    40921 gggtcaacac gaagggaaac gtctgtttgc aattctgcct gcaagcgttc ttccacctta
    40981 cgagaagtta cccatttacc ttctttacca gcaaatggtg agttgttgac caagaaagtc
    41041 atttgaagag ttggctcatc gatgtgtagg attggaagag cttctactgc atctgtcgga
    41101 gtgatggttt caccgacaaa gatgtcttcc atacctgaaa cggcaatcaa gtcacccgct
    41161 ttggcttctt ggatttcacg acgttccaaa ccaaagaaac cgaagagttt tgtaacacgg
    41221 aagtttttag ttgtaccgtc aagtttagaa agggtaactt ggtccccaac cttaactgta
    41281 ccacggaaga cacgaccgat accgatacgt ccaacgaagt cattgtagtc caaaagtgac
    41341 acttggaact gcaaaggctc atctgagtta tctactggag ctgggatatg gtcgataatc
    41401 gtgtcaaaga ttggtgccat agtcgcttct tggtcagctg gatcatctga caatgaagaa
    41461 gttccgttga tcgctgaagc ataaaccact gggaaatcaa gctggtcgtc atctgcacca
    41521 agctcgatga aaagttccaa gacttcatcc actacttctg ctggacgagc tgatggctta
    41581 tcgattttgt taacaaccac gattgggaca aggtcttgtt ccaaggcttt tttcaatacg
    41641 aaacgagttt gtggcatggt tccttcatag gcatctacga ccaagacaac accgtcaacc
    41701 attttcatga tacgctcaac ttctccacca aagtccgcgt gtcctggtgt gtccataatg
    41761 ttgatacgag ttccgttgta agcaacggca gtatttttag caaggatggt aatcccacgc
    41821 tctttttcga tatcgtttga gtccatagca cgctctgcca attcagtacg tgcatcaagc
    41881 gtttctgatt gtttcaataa ttcgtcaacc agggttgttt taccgtggtc aacgtgggcg
    41941 ataatcgcaa tgttacggat atcttctctt aattttgtca tgatttcctc tataatattc
    42001 aaaatttatt ttctaactga acgattatac cataatttca aataaataac ataactcaag
    42061 caagtgtaaa tgttttcact ccgcttttct tttcacgtca agccttttca aagcaagcga
    42121 cttatgataa gataggcaca gtatgcgttt agataattta ttagcccaag aaaaagttag
    42181 ccgaaaggcc atgaagcaag cactcctcag aggggaaatt ctagtcgatg gttgcccagc
    42241 ccgatcccta gctcaaaata tcgatacagg actacaagaa ctcctttttc aggatcgaat
    42301 cattcaaggc tatgaacaca cctatcttat gcttcataag cctgctggtg tcgttacagc
    42361 caacaaagac aaggaacttc cgaccgtcat ggacctgctt ccatctgaca tccagtctga
    42421 caagctctat gccgttggcc gactggaccg agatacaacg ggactcctcc tcttgaccga
    42481 taacggtccc ttgggctttc agctcctcca tccccaatat catgtcgata agacttacca
    42541 agtccaggtt aatgaacttc taacacctga ccatatccaa gcctttcaaa agggaattgt
    42601 ctttttagat ggtactgtct gtaaacccgc aaaactagag attctatctg caagtccctc
    42661 cctcagtcaa gcctctatca ccatttcaga aggaaaattt catcaaatca agaaaatgtt
    42721 cctctcggtt ggtgttaagg tgactagcct caaaagaatc caatttgggg acttcacatt
    42781 gaacccagat ttagcagaaa gtaactaccg ccctttgaac caaaaagagt tacaaatcat
    42841 taaaaactat ttagagatga gtcgataaaa caaaaaaagc tttaaaacta aagctttttt
    42901 cttttattta ccgaaaaatt aaggcgattg ctacaatcca gttaactaca gaaatcacaa
    42961 ttcctaagat attaagaatc ttttctattt tatagtctaa ttgtgactct ttttggtatg
    43021 aaatagccaa gaccaatcct atgataccca aaatcaagcc tacaattgga aataacaaac
    43081 caagaataat cgacaagata cccacaaaaa gtggattttt cttcttttct ttcatgttct
    43141 aagaactctt taaattttat acaaattaat tatactataa aacaatagct tcatcctatc
    43201 attcgactaa tttggaaata aggttagcta gtcttcactt tccctttcca agaatccaag
    43261 ccataagaaa ggatataaat ctcagaaaaa ccttgttttt tcaagtaaag agctgcattt
    43321 gtaactcgtt gcgcacgttg gttctcgtag agaaggacag gtttatcttt acgaagggct
    43381 gcaagactag ttttcaactg acttgaagga atattgcgtg caccaaggat atgttttctg
    43441 tggaattctg ctgggtcgcg caaatcaatc aattgacccg tacgaatcaa ggcttcaaac
    43501 tcctcattgt ccacaatttt agccgcacga cgaatacgaa gatagttaaa gcccatccac
    43561 gccaacattg ctagtataag tgcccacaaa atccaagtaa ccattagttc ttttctccat
    43621 ttttctcaat ataatccaat tctaccttgt gctctctgcg aagaactgct tctgcctcta
    43681 gatagtctaa tttatccatc aaccctgcat cgtaaatccg agatagttcc aacttcatca
    43741 gttcaatatc atataagcgt tttcccatgt aaacaataat accaaatcgt ttgaggaatt
    43801 gctgcacatc atagaatgtt ttcataagac tcattctagc aaaattttgt gtttttttca
    43861 agaagagact cacacaatgc tccttatttt cctatcttct ttggcgattc taaggcaagt
    43921 gtggtacaat aaaaacatga gaattcaaca attacattat attatcaaaa tcgtcgaaac
    43981 tggctctatg aatgaggcag ccaagcaact ctttatcact cagccaagtc tttccaatgc
    44041 tgtgagagat ttggaaaatg aaatgggcat tgagatcttt atccgcaatc ccaagggaat
    44101 caccttgacc cgtgatggga tggagtttct ctcttatgcc cgtcaggttg tcgagcaaac
    44161 tcagcttctg gaggaacgct ataaaaatcc tgtcgcccac cgcgaactct ttagcgtttc
    44221 gtctcaacac tatgcctttg tggtcaatgc ctttgtctct ttgctcaaga aaagcgatat
    44281 ggagaaatac gagcttttcc ttcgtgaaac tcggacttgg gagattatcg acgacgtcaa
    44341 gaacttccgc agtgaggtcg gggtcctctt cttaaacagt tacaaccgtg atgttttaac
    44401 caagatgctg gatgacaatc acctactagc ccaccatctc ttcacagcgc aaccgcatat
    44461 ctttgtcagc aagaccaacc ctctggcaaa gaaagacaag gtgaaactgt ctgatttgga
    44521 gaatttccct tacctcagct atgaccaagg gacgcacaac tccttctact tttcagaaga
    44581 gattctttct caagaacacc acaagaaatc cattgtggtc agtgaccgtg ccaccctctt
    44641 taatctcttg attggtttgg atggttatac cattgcgaca gggattttga acagcaacct
    44701 aaacggagac aatatcgttt ctatcccact ggatattgat gacccgattg agctggtcta
    44761 tatccagcat gagaaaacca gcctatctaa gatgggcgaa cgctttatcg actatctact
    44821 agaagaagtt cagtttgata gttgagaaat gataagaacc aatatgtagg ctagcaacaa
    44881 cctgcacatt ggttcttttt acttataatt aaaagtttcc cctgccaact tatcagctag
    44941 cttgggaaag agagtataaa acttatgggc taggttcaac aaaatcggga gattgagttc
    45001 tcgtttattt tttcctataa tcttgacaat ctttttagcc actgcatctg cctctaagag
    45061 gaagcggtca accgatttaa gataagttcc atctgggtca gcttggtcaa aaaatcctgt
    45121 tcggattgga cctggattga ctgttgtcac atagactcca tagggcataa gttcgagtcg
    45181 cagagcattt gaaaaaccaa tagccgcaaa cttggtcgct gagtaaagac tagacttgcc
    45241 agtagctatt agacctgcca tgctgacgat gttgatgata tgccctttgc tgctttcctt
    45301 catacgagcc gcaaggtgac gagacagatt catcagggca aaggtattga cctcaaacat
    45361 ctggtgaata tctttatcag caatctggtc aaatccctca aaaatcccgt aaccagcgtt
    45421 gttaatcaag acatcaatct tgccatagcg gagataaaga tcagttacca gagcttctag
    45481 ggctgaatcg tcggtaatat caatttcaat caattctgca tgggaataat ttccgtagag
    45541 ttgggctaat ttttccttat ttctaccaag caagatgagt tggtcattgg gcaggagttt
    45601 gaccatttct tgagctagac caccgctagc tccggtaatg agaatagtag gcatacttat
    45661 cctttctgtg actgctagat ttccacttct tccaagtctt tgaccacatg gacattttca
    45721 aaaattgtgg cagcgtcctt cttgagtttg cttatatctt ttgagaggaa acgggcactg
    45781 atatggttga gtaggaggcg tttggcacct gcttctaccg ctacttgtgc agcttgcata
    45841 ttagttgagt gaccatggtt acgagcaatt ttttcatcac ccttgccata agtggactca
    45901 tgaactagga catctgcatt gacagccaga cgcacactgg catccgtttt tcgagtgtct
    45961 cctaaaatag tgataatctt acctggacgt ggcgctgaga tatagtctgc tgccttgatt
    46021 tcagttccgt cttccaaaac aagatcctgg ccgtttttga ttttaccaaa aagcgggccg
    46081 aacggaacac cagcagcctt gagtttttca gcatccagcg tcccttctag atccttttgc
    46141 atgacacgat agccaacaca gaaaatagtg tggtccagct cctctgcata cacagtgaat
    46201 ttatcggttt caagaatttt acccagagaa tcttggtcaa actcatggaa atgaatgcgg
    46261 tagggcagac gagaacctga cacacgaagg ctggttaaga caaatgactt gattccttga
    46321 ggtccgtaga tttccaaatc tgtctgctct tcattggcct gaaaggcacg gctagaaagg
    46381 aaacctggca aaccaaaaat gtggtctcca tgcagatgag taataaagat tttgctgacc
    46441 ttacgtggtc gaattgtggt ttccagaatg cgattttgcg taccttctcc acagtcaaag
    46501 agccaaactt cgttaatctc gtccaaaagt ttcagggcga gacttgaaac gttgcgggct
    46561 ttagagggct gaccagcccc cgttcctaaa aattgaatat ccattcgata ctttctaatt
    46621 aatcaatata taacatggct gtgcggtttt ccgatcggaa atagcgtttg ccagaaaaag
    46681 cagcagcttc ttgcaataaa tcctcttggc tgtagccttt gagacgtttt cgaccatcag
    46741 ccaatctttc caaatcagtc aaagctgtga gactttctag gctgacaact tcctcgtcct
    46801 tgacaggctt catgtaaatc ttaccagact cttcaaagac taattgatgg gagaaaattt
    46861 gcgcaatttc aaagagcaag tcatccgaga ttttctcctc attttcagag aaaatccgac
    46921 caaagccgtc actctcataa caaaaaccaa aggatttacc agacagatta agccgaataa
    46981 aaggcttatt ttctagggtg aaacttggct cagtattgta aagattcagt tcctgactga
    47041 gttctgcaaa ataatccgtc gcagcctgag gacttttttt ctgatagagt tctgcaaagt
    47101 aggcattaac aacacttggc ggaggtgtaa taagtgttaa ctgctcctgc tctgttttac
    47161 cagctagaag ctgatccaga tagaccttgt ccagacttgt ataacctcca tactttagag
    47221 ccaaagtttt aatatcagtc ataaaattct tctaacctcc atttattttt ctcggaaatg
    47281 tagcctgtaa tcacttcgcc gtcttcctga taatcacgtt cttccagaat tgcaacactc
    47341 tctaaatcat gaatcttgta ggactttgaa aaaggcactc gcagggtaaa tgcttcaaaa
    47401 atttccttaa tcttatctag caataatgct tgcaagtttt cacgactgtc ctcagacttg
    47461 gcagaaatga gggtatatgg cgtttgggta ggcgtgaaat cctccaccaa atccgcttta
    47521 ttataaagcg tcaagtgagg aatatcttcc atgtccaggt ctttcatgat ggagagaacc
    47581 gttttttcat gctcctcgtg gtaaggattg ctagcatcga taacatgaac cagaaggtcc
    47641 acatgcttgc tttcttccaa ggttgacttg aaactggaca ccaactctgt cggcaaatct
    47701 tggataaagc caacagtatc tgtcaaagtt acttggagat tgcctcccag atgaatactc
    47761 ttggttgtcg catccagagt cgcaaagagc tcatctgctt catactgggt cttactggtc
    47821 aagatgttca tgatagttga tttcccagca ttagtataac caatcaaacc aatcttaaaa
    47881 gtgctagact ccaaacgttt ttctctgaca gtcgcacgat ttttctcaac caccttaagc
    47941 tggcgctcga tatccgtgat ttgattgcga acgctacgac ggttcagctc cagttggctt
    48001 tcaccaggac cacgggaacc aattccccct gcctgacggc tgagcataat cccctgacca
    48061 accaagcgag gcaagaggta tttgagttgg gctaggtgga cttggagctt cccttcatgg
    48121 cttcgagccc gcatggcaaa gatatccaaa atcaactgca tacggtcaat gaccttaaca
    48181 ccgagaactt cctctagatt gacattctgc cttggggtca gacggttgtt gacgatgaca
    48241 gtagtgattt cttctgcatc caccataagc gcaatctctt ccaacttacc agagccgacg
    48301 aaggtcttgg aatcatattt ttcacgtttt tgtctgtagc tatctacaac gactgcccct
    48361 gccgttttcg ctaaactagc caattcttcc atggagaggt caaaactgtc cataccctgc
    48421 aattccacac caatcagcag gactcgctcc tcttttttct ccgtttcaat catctaaaaa
    48481 ctcctctatc tggcttaaaa tgcggtcttg tacaccagat tctccaatct gataaaaggt
    48541 gacctgcatg cgattacgga accaggtcag ctgacgcttg gcaaaacgac gggtcgcctg
    48601 tttaagactc tcacgagctt cctccaaggt ctgctctcca cggaaataag gaaagagttc
    48661 cttatagcca attcctttag cagcctgtac attaggggaa tggtcaaaca gccacttggc
    48721 ctcatccaaa agcccagcct caaacatcaa atccactcgg tggttgatac gctcataaag
    48781 ttgactacgt tcatcatcca agcagataat cagcggttca tacaaaatct cttgattttc
    48841 caaatcctga ccaaaatggg caatttctaa ggcacgcata gcacgacgac gattaaactg
    48901 gggaatctca aggcctgctt gctccaccaa atgggctaat tcctcatctg aatatggctc
    48961 caaactagct cgataagcta aaatctcctc atgaggagtc tccccaccta ggtggtaacc
    49021 ttctagcaag ctctggatat aaagtccagt cccaccggcg ataatggcta gcttgccacg
    49081 gctgtgaata tcctcaatag tcatcttagc ttctgaaaca aaatcaaaag ccgagtaaga
    49141 ctcagttatc tctctaacat cgattaaatg atgaggaaca gctgcctgct cttctggact
    49201 agccttggcc gtcccaatat caagtcctcg atagacttgc tggctatctc cactaaccac
    49261 ttcgccatta aagcactttg caacttcaat agctagagcc gtctttccaa cagcagtcgg
    49321 tccaacaatc acaattattt ttgttttcat cttttttcct tgaaaaattc ccattttttc
    49381 gttactatta ttataacaca aaaaggtcag tcagaaaaat gtgacctctt gaggaggctg
    49441 gctgattgag aatataaagg aggaagactc atggctaaag gattcgctaa aggtcttgta
    49501 acaggtgtcg caggaactgt cgctgccgtt gcaggtgcag tatacgcatt taaaaagaaa
    49561 gtaatcgaac cagaagagca aaaagcagct ttcatcgaag aaaaccgtaa aaaagcagct
    49621 cgtcgccgcg tatcacgtta agaaacaaaa gaagttggga ttattctcaa cttctttttt
    49681 ctattctttt aaatagctag gtcaaacttc aactgtggct taacagggtc ataatccacc
    49741 aactcaaaat cttctgcttt gatatcaaag aaattagtcc catcaggaac atttaaaacc
    49801 aagcgtggtt ggcagtttga cggctcccga cggagcaatt cctgagcttg ttcaaattga
    49861 ttatcataga tatggaggtt gttgatgaag tagaagaact tcccaacctt ccagccaaaa
    49921 tgtttagcaa tcatcatctg caaagccaca tactgcatag cgttgatgtg gtgggccacc
    49981 agcatatcat tggagcgctg ggtcaaggtc gcatccagat agatttcccc atcaacacgc
    50041 cgaacatcaa acatggtctg aaaggcgcac gggagcagcc catctgtttc ttcgaaagct
    50101 tggtaatccc agagagaaat aatattgcgg cggttccaag gattggtttc caactgtttg
    50161 agaagcttat tgataatgtc gtgtttctta acaacggcac catagcgctc accaatggtt
    50221 cccgtgtctc caacttccca gtcattccag tagtgaacat tgtacttgtc attaagcact
    50281 tctaagctat ttgactggtc ttggtaaatc cagagaactt ctttgatggc ggatttgatt
    50341 gcaatgggac gcaaggttat gataggaaat tctcctttag ataagtcgta ctcggaaaag
    50401 gcaccagtta catacttgga attagcaaca gtcccatcct tgtacttagg acgagcctgc
    50461 tctgagaaaa caccttcctt tagaatgcgt tcaatattct ctttaaaaat cgtatctgct
    50521 tttgtcattt actctcacct cattcattgt cctaactagt atagcataaa aaataaaaga
    50581 ggaacattac taactctagg ttagcatttt cctctctcat tatcttattg caatacaagt
    50641 gatgctgctc cgataactcc agcgtcattt cctagagttg caagagctaa tttagtagat
    50701 gtgcgtactt gtgggaaagt attttcgtca tagacttttt gaacaccttg tagaaggaat
    50761 tctcccgcag ctgacacacc accaccgatg acgattgttg atgggtttag gattgaacca
    50821 atgttagcac aagcgattcc caagtaacgt gagaagttac ggtaaacaat caaagcaagg
    50881 tcgtctcctt cttttgcgag atcaaagaca gtcttagcag ttacttcttc tccgttatca
    50941 atcaagcgtt tcaaggctgc atcgccttcg tattcatcgg catagcgacg agtcaagttg
    51001 acaattcctg ttgcagaagc gactgtctca agacagcctt tcttaccgca agtacatgag
    51061 attggctggt caaagtcaac agtgatgtga cccaactcac ctgctgcacc agcaacaccg
    51121 tgaagcaatt tgccttctgc gacgataccg ccaccaacac cagtaccgag tgtcataaag
    51181 acaacatctg gttggttatc accagcaccc atccagcgct caccaagagc tgctacgttg
    51241 gcatcattat cgatgaaaaa tggaatgccc aaagcttttt caatcttttg tttgattggt
    51301 tgaagggttt tccagttcaa gttgtaggca ccgataacag tccctttgtc acggtcaacc
    51361 acacctggtg atcccattcc aatgccttgg aagtccgctg ctgccaatcc aagcaagtcc
    51421 aaacgatgtt gaatagactc aatcatatca tcaacgatat gacttccctc atccaaaatg
    51481 ttggtcttga ttgaccattt tccttggatt tctcctgctg ttgttaagat tgcaaatttg
    51541 atagaagttc caccaaggtc aatcccaata atcttttgac tcattatatt ctcctttttc
    51601 attgtgtagt aattgaaaat gcttacagta ctagtatatc aaaatccatt cacttatgca
    51661 aaggtttgcg taaatgaatt ataaggaatt ttttcgccta ccagtatctg ttaaccatct
    51721 aaatgatcaa tggcatattg agctgcatca tttgaaaatt tatcaaaatc agaagttaat
    51781 tgtctataca tacgtttttt tgacatgtgg aataacgaat tataactttt tgcctttcct
    51841 aaagcagcag aatattcact attgctatca ttactagaag aagctgtact tgcttgacct
    51901 tccttccaaa ctccgtcagc gccaacataa taacgtccac catcaaccca ttcattgaca
    51961 gccattttac catccgattt tagatagtaa tttccttgcc atgtactata agcataagaa
    52021 ccatctgatg tcaaataata ccaagcttga taggtggcat cataaaccca ttcaccttta
    52081 gccattttac catctgattt caaatagtag tttccttgcc atgcattgcg agcatatgaa
    52141 ccatctgatt tcaagtaata ccatgcttgg taagaagaat cataaaccca ctcaccttgt
    52201 gccattttac cgtttgattt aaggtaataa gctccttgcc atgcattttt tgcataagaa
    52261 ccatctgatt tcaaataata ccaagcttga taagaagagt cataaatcca ttcactctgt
    52321 gccattttgc catcagcttt caggtaatag tttccctgcc atgcattttt cactagattt
    52381 ccatttccat caaaatagta ccaagaaccg tcctgcttaa cccaaccact tgctgtggat
    52441 gaagttgtat cagtttgagt tgtagccgct tgttttgctt taaaagcacc cttaggagca
    52501 tttttcaatt cgcaagccac accatcatga tcgcggtcta acttggcaga ataaccaggt
    52561 tctccctcat gaagatccga atatccatta gcccaagctt ccttacagct cgaaaaatgg
    52621 atgttttctt ccgccaaaac tggttgtgaa aacaaggcta aaattggcaa cgtcaccaga
    52681 ctcattttta aaaatagacg tttattcatt tctttctccc ataattatga tatcgatttc
    52741 aatattattt tatcaaactt atttcagcaa ttcaaggaaa cttctggtct tttctacaaa
    52801 ctcctttggt tttgccttat tcaagacatg agggccatca ggaatgatct gaaactgcga
    52861 atctgttaac agtctatgga gagctttcat agaactaaga ttcggtttat ctttgctgcc
    52921 acaaattagt aaggttggat aggagcaagt ccctgctata tccgttaaat caagtgtctt
    52981 caattcctca gaaactccga ccataagagt cttgtctgct ccctgttttt caaatactct
    53041 tttgggaagt agtttaaaaa tcagcaactg aagataaaat aggatattcc ctgctaattt
    53101 aagcgggcat cctgacagaa tcaaagctcg aagatttggt aaatcgtaac tggaaagttc
    53161 tagtgtcagg gcagcaccta aggacaatcc aatcaaaaca aaaggttctg tctcttgagc
    53221 taggtgctga taaactcgct ctttagcttg ttgatagtta ctaactccag aaggaaataa
    53281 ctcgatagcc tcagaaggat aatctgtcag tagattccga acttctttcc aagactctgc
    53341 tgactgccct aacccatgca aaaatatcaa tttcatctag ttctcctcaa ggcttagttc
    53401 atacaagcct ctcactgcat tacagccgta aatagcttct gcttgggtta aatctgccaa
    53461 ggtcaagact ttctcttcta cctgtcctgt ttctagcaaa tactgacggt aaattcctgg
    53521 taagattcca agtcggatag gcggtgtgta gagttttcca gcgattttca gaaccaaatt
    53581 tcctatagag gtttcaagca gttctcctga cttattgtgg taaatcttct cttgttctcc
    53641 taggctcaaa tgcggtcggt gagtggtttt aaagtaggta aaggattgat tcaaagcagc
    53701 ttcctgaagg cagacttggg cctgacaaaa gcttgtactg agaggggtta atacttgacg
    53761 attgacttct atctctccag atttgctaag gctgattcgc aagcggtaat ctcgattagc
    53821 ttcacaatcc tgacactctt cctcaatctt gtgtcccaag tcttctgcat caaaaggaaa
    53881 agcaaaataa cgactagctt ttctcagtct ttccagatgt tgatcttcaa acagcaggtt
    53941 cttctggctg atttcccctg tcgtaatcag ttggaagcga gcttgtttac gataaagaac
    54001 tgctgccttt tgatgaacct ctcggtattc agattcccat gtgctatccc aagtaatccc
    54061 tccgccaact ccataaatgg cttgaccttt gtgaagttga atggtacgaa tggccacatt
    54121 aaaaatccgt cgtccatttg gaagcaagag accaatcgtt ccacagtaga ctccacgcgg
    54181 ttgaggctcc aagtccttga taatctccat tgtcgcaatt ttcggtgcac ccgttatgga
    54241 accacaagga aagagtgagc ggaagatttc aacaaggtcc acatcctctc gcaactgact
    54301 cttgatggtc gaagtcatct gccaaacagt tgaatactgc tctacctgac acagacgctc
    54361 cacgtgctcg ctcccaactt cagaaatacg gttcatatca ttgcgcaaga ggtccacaat
    54421 catcatattt tcagagcgat ttttgggatc ctgttccaac caactggcct gttcaagatc
    54481 ttcttggtca gttaccccac gctgagtcgt ccccttcatt ggtcgtgttg tcaactcgcg
    54541 atcattttgc tcaaaaaaga gctctgggct catggaaatc actgccatct cgtcatgttc
    54601 cacataggca ttgtagcccg cctcctgctc taccaccata cgattgtaga tggcaaaagg
    54661 attggcactt aacttttgct tgagttggac ggtgtagttg acctgatagg tgtctccctg
    54721 cctcaagtga tggtgtatct gggcaatggc cttttcatag tctgctgcag acgtcacttc
    54781 ctgccaattt gagggcaaat caatatcctc ataagtcaga ggaatagggg aagtttctac
    54841 gctatcatga acagtaaagt aaagcaggta ctctcccagt aggggatcct tgtgaactgc
    54901 taatttttcc tcaaaagcag gtgcagcctc gtagctgaca taccccacca cataataacc
    54961 ttgctcttgg tagctttcca cttgtgccag caaatctgcc acttcttcta catttctcgt
    55021 tttcaactct ttaataggct gggcaaaggt atatctctcc cctaaagtcc taaaatcaat
    55081 cactgttttt ctatgcatac cttaagtata gcataaaaag gcagatacag acaaagctga
    55141 tctacctttt tacgatttta ttcattctat gcttgtggtg cagtaaatag atcaccagag
    55201 aaaccgtctg tgtttttaag gagagcttta aagactttcg atttcaagac aactgtattt
    55261 cggtatttgt ctttaatact actatcgttt agttccgtta aatctttagt aacagcctca
    55321 tcaaacatag tcttcaactg ttcataggtt gaaatttgag tgccattaat ttcaattggt
    55381 gcaaaacctt ttttagattt tgtaagaact tccccatacc attgcttctt ccaatcttca
    55441 aggtttgaaa attggttatt agaaactttc ttaataatga aatcatcacc taatagaccg
    55501 ttattttctt tattggctgc accttgatgt ttgcttgaaa catagtcaat gaacccatgt
    55561 tcatatccat agtaacccca catacggaag gcgttatgtt tgaaggatag agaaccaggg
    55621 gcaccttgac tcgtattacc gccataaata ccagccatca tattaacatt gacatatgcc
    55681 gtaccaaagt cctctgggtg gaagacctta ttacctggat ttccgtgaat ggtcatgaaa
    55741 ttattattta ccaagtcatc gatggtttca aggttagttg ttttctcagc gtctatcaaa
    55801 tcacgcactt tgtcccattg gtgaggacca cttagtttat ttctgtccat tggtcgacgt
    55861 gtttcgcgat caattttctt gaaccactta ctattgtcac ctttaacctt aggaagaaca
    55921 gcctcagctt ctgcataatc gagcatcatc atagcttcat tgtagttctt catgtaatgg
    55981 tcgatttggt cacgtgtttg aagtttggta ggatctggat tataccattg gtttccatca
    56041 tttgaacgtt caaatgccat atttaatcca agtgcgccat attcaccttg atgtccatgt
    56101 tctgctggag tttgtaacat accttgagca aatgcttcaa gatctgtacc ctgtcgatgt
    56161 ctatgacctc ccagatatgc cattcggtca tttacgtggg tagtctcatg tgtaaaggca
    56221 gatgtgccat attcacttat taaatccgac ataacaaaat atacagcatc cataggctgt
    56281 ggatcagcaa agatgtaagc atacgctcca tacccatact tataatcatg atacttatca
    56341 atacgtccaa agaattcacg aataggtgca taatccggtt tatcttttcg atgaccaaat
    56401 ctatcaggcc aaccaccggg tgcaccatga ttatcccata caggagttgg aactacattt
    56461 tgactcttaa gaagtttatc gcggacatta tcagtggcaa ggcgtgacca aaaatctaag
    56521 taattaactt gctctttagc acgtttattg atttcactct tgaacgattc acgtttttct
    56581 tctgtatctt taccatactt ttcaaacgaa ctaaatgaga tagtattata tgttgaaatc
    56641 ataaataaat gtgcatcttt caagttcaga agcgataaaa tcatgcgtcc atgttgtccg
    56701 ttattaagtc cttcatatag acgatatttt ttattagcaa atgcagggtt agttgacggt
    56761 tgttcaacta cataagcatt attttcaata gctttcttaa accaaacatt tatgtctgtt
    56821 tcatttgtga atagtttcat attgtaggtc aagaagtcat gtaagtttcc agaaagagta
    56881 tttttcgcca ccacttcacg gaaggactcc tgtgtacgac ttcccttaat atagtcctct
    56941 tttgaaccaa tttctattaa tcgatctaaa acacttacat tcttaccata aaaatctggt
    57001 ttgaatagca ttaattcttt aatattgaag ttatcaaatt tcacaccgta ataacgattt
    57061 aggtatgtta atcctaacag gacagcagct ttgttatctt caattttctt aatcaaggca
    57121 cgttttgcag cttcatctgt attcagttga tgatcttcat tttcaactaa ttttgtcaca
    57181 aatgtattaa gatgatcttt tacttcttta aagctttctt ctaagtaaag attcttaatt
    57241 gcattaactc tgttatcccc agttcttcct aatcgttgat aaattggatc agattgtaat
    57301 tcaattggac ttaaaatacc ttcaatagca ctaattaaat ctgcacgatc tttaacaacc
    57361 atatttggtg tatagacgac ttcaccaagc tctgcgacac tgtattcttt tacttgctta
    57421 acttgagagt ctttaggaga aatcgtaaag atatcttttg tcttatctgc gtaatgaacc
    57481 ataatatggt cagcatctgt aaggtctgta ataaagtcat tacctttcat tgcagtcaca
    57541 gacaatactt ctttattcat taatggacta tcagttgtaa gcttgttccc ttgattcaca
    57601 atccattctt tgttgtagaa cggttggagt ttttcaacat tacgataaac aagctcacga
    57661 tttgcattat aatcttgaat tgttttgtat tcttcatcac gtaatatacg gcgattcaac
    57721 ttatcaacca aatgctcagt tacttcaaat gtatcagcag tgatacccat atccttaatt
    57781 ttcttatcag cttctacctg tgaaatttct ttaattttag acgattgttt atgggtttta
    57841 tctccagaac tcacaccgat aactgttgca ttattaggtt taatccaatt gcttacaaat
    57901 tcatcatcca tatcattaga accaaagaaa atatcaccac gcttaacatt cactaagctg
    57961 atattgttat caatggttcc ccaaggccag tctttaccaa ttaaaccgcc tacatcacct
    58021 ctagcaacat caatagtacc tttggctaca gaatttctta cattagacca agcaccaaca
    58081 tctcttggat taaaatcatg agctaaatgt cctactatag cacctgcacg agtatttaaa
    58141 cctttaagtt caacatctgc ataagcttta tttaaattgc ctcgataaat ctcagatgca
    58201 atcccagcca agttccaccc tttatcacca acagattgaa cttttccgat aaaagcaaca
    58261 ttagtcataa tacctgcatc atctaattta tccaaaatac ccgcaacatt gttattacca
    58321 acgatagtac ccgttacttt aatattttca acagttgcat ttttcactgt ttgagctaat
    58381 gaagctaatt gatttgccca aggcatatta atattaacgt taattaaatt aatatttttg
    58441 atagaacccc cttcaactct atcaaataat ggacgagcag tgttatgaat ggagaaatgc
    58501 ttaccatcaa cacttgttaa gtgacctgta aatttacctg ttacatatga tttacttggt
    58561 gtaggtacat ttgttgcatt taaatccgat cctaatttaa actcaccgtt aggatttttc
    58621 tgcatagcat ctactaaatc tttgaagtta tagtaaacgt tattttgcga tgctttgggt
    58681 ttctctatgt aataagtgta tgtttgactc aaactattat ttgaatcacg ttggattaaa
    58741 tcaggagctg aagcagtaac tttaaataag gatgtctcct cctcagttac ttcctctata
    58801 ttagtaatgg caagccttgt tactttatta tgattagtgg taatttttag ataatatgac
    58861 gttagatttt ctggaacagt ttctagaagg ctactatctg tttcatttcc attctcatcc
    58921 actttcatca atcttgtttc tttaatatct ttaatctcaa cttttttaag gtctaactga
    58981 acttctttat cttctaatat ttcagtttct tcaccgttac ctcgatcata gaccatggtt
    59041 gtggatagtg tataaccttg ataatatttc aagttgtcta aagtagcttg taagttattt
    59101 tcttctaccg ttacttcttt aacaactgtt ccagtattat cttttagagc tactttaatc
    59161 gatttaattt ctactccagc tggtttagtc aatgtataac tagctgtcgc actcttcttc
    59221 aagacatctt tatctgtttt agcccattcc aaggttggtt tctctaactc ttttgtgcca
    59281 ttcttaataa ttttgtcttg aggtttttca atcactgttt ctgtgatagt aggagcgtca
    59341 cttgtttttt ctccgcgaat tgttttatag gtttcagtaa tttgtttctt atcgtttaca
    59401 ccttcttgag ttacttgtct tgttccgcgt tttaaagtgt catcttcttg ttcttttgtt
    59461 tcaaaaggaa tgatttcttc tcttgtctca accgttgtcc cttcaattgg ttttgtacca
    59521 cggattacct gttgatttac aggctccttg gtgacttccg tactggttga aagaacttgg
    59581 tcagttttaa cccctcctat tgttttatag gttgtttttg taacttgact tcctttttca
    59641 ccatttcgta ggacagtttc ttcgtccgtg tacttggttg ggtcctcagt cgtttcagtt
    59701 ttatagtcaa gttctgtagt tgattcttca acgagtgttc cttcagtcac cttatactca
    59761 ggtaattgtt ctggaacaag agcctcaccc acgtaatctt cttcttgcgt ccccttagct
    59821 gttttagtct cctcttttgg ttctacagtt tcttcagcct tggtatctgg agttgactct
    59881 tcttgtttcg gtgtctcttc cgctccccta tcttctttag gattgtcttc ttgtgatgat
    59941 tcttttggtg tacttggttg ctcagcttgt gtaggttgca cgggttgttc tgggactttt
    60001 gcttgttcta ctggtggttc aacttttgat tcctcagctg gtttgtctga tggttgactt
    60061 tctggcttaa ctgctacttt ttcctctgat tttgactcaa cttctccacc tacttcttca
    60121 actggagctg gttctgctga atcttctttc ccctcttcta ctttaggaag ggtgtcgtca
    60181 gtaggtttta cctccgattt tggttcttcc tttggacttt cttctgttct aggtgcttct
    60241 tcttttggag tttcctctgt ctctactact tggttttctg tcctagcttg ctcctgattt
    60301 gttgttgatt gaggagtctc aacttcgact acagtcacct ctccaggttt tgctgaggtt
    60361 tcttctaaaa cagtgtccaa gccaagcgtt ttgaggatgt cacctgatag ataaccaaca
    60421 tagcgatagc catccatttc aacaacaccc tctcgactag ccagcgctaa ggtcgcaact
    60481 gggtctacag cccctgcact aggaagaact accaatccca tagctccaac tagaaagacg
    60541 ctagcaattt tctttctctt gtagattaaa agcaagctcc caacagtcag caaaccaaaa
    60601 gctgtcaaaa cagatgcttc tgtccctgtt tgaggcaact gatctttttg atacaccaaa
    60661 ccatatacaa cttcattcct gtcaggcttt cctgtctgaa ttaaatcttt agcttcttgt
    60721 gaaataatct ctttatttac atagtgatag gtagctgcgt ccactacaga aggagccatc
    60781 aaaaggcttc caagaaatac agagcctaca actcccttaa tcttacgaat tgaaaaacgg
    60841 tcttttttaa acactttcat ctcctttatt cattctcaag actttctaat agcatcttgc
    60901 ggatagtgcg cacgcgcacc tccgattaat tttggacgac tagccagtgc cgttacatgg
    60961 gcatgaccaa tctctctcaa aatagggcga atcggaacct gaacatgctt gacatgcatg
    61021 ccaattgcag tgtctccgat atccaatcca gcatgagcct tgataaattc aacctcaact
    61081 ggatcctgca taaacttaaa ggctgccaac tgccccgaac ctcctgcatg aagagtagga
    61141 tggacactga caatttccag atcaaactgc tctgccacct gacgttcaac aacgagagcc
    61201 cgattgacat gctcacaacc ttgaactgct aaatggatac ctctactacc tagaataccc
    61261 aagatagtct ccactatcag ctcaccaatc tcttgactgg attctttccc aatctgacca
    61321 cctagcacct cactagaaga tagacctaaa acaaaaagga ccccctgctt caaattggtc
    61381 ttttctaaaa catcttccac tacctgacgt gtttctcttt gaatctgtgt ctcgttcatc
    61441 tctgttacct ctgttgtcac tcttctatca taccgttttt tcttgttttt agcaagatag
    61501 acaacctata aagtctgccc aattacgcat aaaactccca gaattgactg ggagttagct
    61561 agtttctatt ctatttatat atatttcaac tttcgttcct ttttggggtc tagaatcaat
    61621 cttcatctgg taattggctc caaaatgaag tttgagccgt tgatcgacat tttgaagacc
    61681 aactccccca cgtttgagtt gactttgact actatcacca gcatcttgga agccaacgcc
    61741 atcatcctca atacggatga ccaatcccga atcctgtttc tggacagaaa gtttaatatg
    61801 gccctgacct tccttttcct taatgccatg gtaaagagca ttttctacaa ggggttgtag
    61861 gaccagcttg ggtaagacta aattatcaaa ggcaacattt tcattaattt cgtattccag
    61921 cttatctcca tagcgttgtt tctggataaa gagatactgg cggacatgat tgatttcgtc
    61981 agagagacaa atcaagtcct tgccttgatt gagcgccaag cggaaatagg ttgccaagga
    62041 cttggtcacc tgcaccactc gctgactatc atgaaattca gccatccaga tgatggtgtc
    62101 caaagtgtta tagaggaaat gtggattaat ctggctcgaa agggcttgaa gttggtactg
    62161 acgggtcgtt tcttcctggc tacgaatagc taccatcaac tgatcaatct gatccaacat
    62221 agcattaaat tggcgagtta cttctctcag ttcataggca ccaacttcct tggcacgaag
    62281 attttgagca ccagaagcaa tttccaacat ggtttctctc aaatccttca aaggagcaat
    62341 ccagcgttta agactgaacc acactaagca gagacaaaca agaagagatg tgacactggc
    62401 cccaagcaag gtccacaaga gctgactccg aacctggtct aacttttcca atgatgacac
    62461 gccaagtacc gtccaatcag ttcctgcaat cttctcttga ctgacgtagg atttgtgacc
    62521 aggagtataa ccctgacctg tctcgatgta gggtttcata gcctccattt tgctagacga
    62581 actataaact gtgtgttgag gatggtagac aaattcatgg ttttcattga taatgaaggc
    62641 aaagccctgc tgccccaact ggagttgatt gagataggct tccagagttt cataagaaat
    62701 atccaaacga agcacaccaa gattggctcc ctttgcatca acaagttctt gagtgacaga
    62761 aatgacccac tgactatctg atttacgagc tggagtcaaa acaggcatag ctccctgatg
    62821 aatagccttt tggtaccaat cctcagccat catatcagag gaagttttca tctgcacact
    62881 gtcatctgta gaaatgacct gaccagattt ggtcaccagc acaacagttt tcaagtcctt
    62941 atctgacttc aagatggtca aaaacaaatc tcggattccc tcgaccttgt cttgactggg
    63001 attctcagca taggccagaa catccgtctg ctgggtcaaa ccagtcgagg tggtttctag
    63061 ttttttgata taagactgaa taaagtggct agtctggctg atggtcgttt ggctgttgcc
    63121 ctcaatggtg gcctcaatgg ctgaagaact tgattgatag tagaaagttc caaccagagc
    63181 taggagaatg agaaagacca gaaagatgga aataaccatt ctaactaaaa gagaagaacg
    63241 cttcatcggt cttctccctt cttaaactga cgaggtgtca cacctgcaat ctgcttaaaa
    63301 cgttgggtaa aatagttcat atcttcaaaa ccaaccttct ctgcgatctc ataaatcttc
    63361 agatctgtag ttaaaagcaa gagcttggct tgtttaacac gttctctcac cagataatcc
    63421 tgaaaaggca agcccaactc tttcttaatc aaggaactca gataggtcgg actaaaacct
    63481 aagtcactgg ctaaagactt taaactaaat tggctatcag ccagatgaga ctggattttc
    63541 tgggccatgt ttccttcaaa cctattagtc aataaatctt gtaactgctc ttctttctct
    63601 tccttgtcta gtttttgttt gattttcccc aacatttcct caatatcctg acgagaaaag
    63661 ggtttgagca ggtagtcgtc cacacctagt ttgacagcag acaaggcata atcaaaatca
    63721 tcgtaacctg ttaaaaagac caaatgaacc tgaggatagg tttctcgtac cagactggcc
    63781 aactggatgc catttagatg aggcatgttg atatcggtta aaatgatatc tggcacctgc
    63841 ttttggatca attcccaagc ctgccttcca ttttcagcct gaccgatgat ttccatatcg
    63901 taggctgcta cattgaccag tttagtcaaa ccttgtctta ccagatattc atcttctacg
    63961 attaagattg tgtaggtcat gctctgctcc tttaccactt actagtatca gtatagcaaa
    64021 attctcctct aactgcttag gaaagacctc ttatactcaa taaaaatcaa aaagtaaact
    64081 aggaagatag ccacaggttt ctcaaagtat agctttgagg ttgtaaataa aactgacgaa
    64141 gtcagatcaa agtatagctt tgaggttgta
//
LOCUS       DAVAZT010000004        51676 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVAZT010000004 DAVAZT010000000
VERSION     DAVAZT010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51676
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.004"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(54..362)
                     /locus_tag="VQT45_000208"
                     /pseudo
     CDS             complement(54..362)
                     /locus_tag="VQT45_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            complement(604..900)
                     /locus_tag="VQT45_000209"
     CDS             complement(604..900)
                     /locus_tag="VQT45_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2358609.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            complement(884..3043)
                     /gene="pfbA"
                     /locus_tag="VQT45_000210"
     CDS             complement(884..3043)
                     /gene="pfbA"
                     /locus_tag="VQT45_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HET2358610.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVISTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKESVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(4173..5399)
                     /locus_tag="VQT45_000211"
     CDS             complement(4173..5399)
                     /locus_tag="VQT45_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HET2358611.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVFEVGPGDEVIVPAITYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(5442..6134)
                     /locus_tag="VQT45_000212"
     CDS             complement(5442..6134)
                     /locus_tag="VQT45_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET2358612.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGNLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSTEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFKVLK"
     gene            complement(6320..8071)
                     /locus_tag="VQT45_000213"
     CDS             complement(6320..8071)
                     /locus_tag="VQT45_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2358613.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYRLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALVDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMAYTL"
     gene            complement(8061..9806)
                     /locus_tag="VQT45_000214"
     CDS             complement(8061..9806)
                     /locus_tag="VQT45_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2358614.1"
                     /translation="MSIIQKLWWFFKLEKHRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSPAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTELRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSEVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILNPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGRHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(10012..10308)
                     /locus_tag="VQT45_000215"
     CDS             complement(10012..10308)
                     /locus_tag="VQT45_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HET2358615.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(10461..10917)
                     /locus_tag="VQT45_000216"
                     /pseudo
     CDS             complement(10461..10917)
                     /locus_tag="VQT45_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            11051..11878
                     /gene="xth"
                     /locus_tag="VQT45_000217"
     CDS             11051..11878
                     /gene="xth"
                     /locus_tag="VQT45_000217"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HET2358616.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11890..12033
                     /locus_tag="VQT45_000218"
     CDS             11890..12033
                     /locus_tag="VQT45_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET2358617.1"
                     /translation="MDYNAVIPEFLVSNIEQSRSFYCGLLGFRIEYQRSEENFLFLLK
                     SVN"
     gene            12033..12272
                     /locus_tag="VQT45_000219"
     CDS             12033..12272
                     /locus_tag="VQT45_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET2358618.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRPLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     regulatory      12656..12751
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            13151..13732
                     /locus_tag="VQT45_000220"
     CDS             13151..13732
                     /locus_tag="VQT45_000220"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HET2358619.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAAAGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13732..14994
                     /locus_tag="VQT45_000221"
     CDS             13732..14994
                     /locus_tag="VQT45_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HET2358620.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LSAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(15081..15947)
                     /locus_tag="VQT45_000222"
     CDS             complement(15081..15947)
                     /locus_tag="VQT45_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HET2358621.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEEIKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(15934..16704)
                     /locus_tag="VQT45_000223"
     CDS             complement(15934..16704)
                     /locus_tag="VQT45_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET2358622.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            complement(16730..17584)
                     /locus_tag="VQT45_000224"
     CDS             complement(16730..17584)
                     /locus_tag="VQT45_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HET2358623.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELMPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYLNNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            complement(17741..18145)
                     /locus_tag="VQT45_000225"
     CDS             complement(17741..18145)
                     /locus_tag="VQT45_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HET2358624.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVRI"
     gene            complement(18215..19696)
                     /locus_tag="VQT45_000226"
     CDS             complement(18215..19696)
                     /locus_tag="VQT45_000226"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HET2358625.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIVYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSADHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFARVLEDAGVYKQTEQGQTAFMRFVEHVGILLD"
     gene            complement(19715..20893)
                     /locus_tag="VQT45_000227"
     CDS             complement(19715..20893)
                     /locus_tag="VQT45_000227"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HET2358626.1"
                     /translation="MAQHLTTEALRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVFENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            21058..22065
                     /gene="galR"
                     /locus_tag="VQT45_000228"
     CDS             21058..22065
                     /gene="galR"
                     /locus_tag="VQT45_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HET2358627.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFRNYSQAKGIYHDELVFQGN
                     FTAQSGYDLMKEAIQNLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHDRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(22111..23148)
                     /locus_tag="VQT45_000229"
     CDS             complement(22111..23148)
                     /locus_tag="VQT45_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET2358628.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAVEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLQSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(23149..23502)
                     /locus_tag="VQT45_000230"
     CDS             complement(23149..23502)
                     /locus_tag="VQT45_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HET2358629.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(23746..24636)
                     /locus_tag="VQT45_000231"
     CDS             complement(23746..24636)
                     /locus_tag="VQT45_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HET2358630.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            24769..25305
                     /locus_tag="VQT45_000232"
     CDS             24769..25305
                     /locus_tag="VQT45_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET2358631.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(25472..26278)
                     /locus_tag="VQT45_000233"
     CDS             complement(25472..26278)
                     /locus_tag="VQT45_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HET2358632.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(26623..28143)
                     /locus_tag="VQT45_000234"
     CDS             complement(26623..28143)
                     /locus_tag="VQT45_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HET2358633.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLVQKEKENLVIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGKTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMEPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(28136..28864)
                     /locus_tag="VQT45_000235"
     CDS             complement(28136..28864)
                     /locus_tag="VQT45_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2358634.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            complement(28879..29643)
                     /locus_tag="VQT45_000236"
     CDS             complement(28879..29643)
                     /locus_tag="VQT45_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HET2358635.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVVDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHDIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(29647..30090)
                     /locus_tag="VQT45_000237"
     CDS             complement(29647..30090)
                     /locus_tag="VQT45_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET2358636.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKFQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(30772..31068)
                     /locus_tag="VQT45_000238"
     CDS             complement(30772..31068)
                     /locus_tag="VQT45_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET2358637.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETAKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(31090..32154)
                     /gene="pepA"
                     /locus_tag="VQT45_000239"
     CDS             complement(31090..32154)
                     /gene="pepA"
                     /locus_tag="VQT45_000239"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HET2358638.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            32555..33256
                     /gene="galE"
                     /locus_tag="VQT45_000240"
     CDS             32555..33256
                     /gene="galE"
                     /locus_tag="VQT45_000240"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET2358639.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            33679..34638
                     /locus_tag="VQT45_000241"
     CDS             33679..34638
                     /locus_tag="VQT45_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2358640.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKEISESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLGFILLLWRGGRKDAD"
     gene            34628..35584
                     /locus_tag="VQT45_000242"
     CDS             34628..35584
                     /locus_tag="VQT45_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HET2358641.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLTLQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            35581..36333
                     /locus_tag="VQT45_000243"
     CDS             35581..36333
                     /locus_tag="VQT45_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2358642.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGS
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            36429..37394
                     /locus_tag="VQT45_000244"
     CDS             36429..37394
                     /locus_tag="VQT45_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2358643.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPAILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(37619..37861)
                     /gene="yidD"
                     /locus_tag="VQT45_000245"
     CDS             complement(37619..37861)
                     /gene="yidD"
                     /locus_tag="VQT45_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HET2358644.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(37861..38583)
                     /locus_tag="VQT45_000246"
     CDS             complement(37861..38583)
                     /locus_tag="VQT45_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET2358645.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(38570..39139)
                     /locus_tag="VQT45_000247"
     CDS             complement(38570..39139)
                     /locus_tag="VQT45_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HET2358646.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKSQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(39158..39886)
                     /locus_tag="VQT45_000248"
     CDS             complement(39158..39886)
                     /locus_tag="VQT45_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HET2358647.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(39886..40626)
                     /gene="xerD"
                     /locus_tag="VQT45_000249"
     CDS             complement(39886..40626)
                     /gene="xerD"
                     /locus_tag="VQT45_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HET2358648.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(40617..41078)
                     /locus_tag="VQT45_000250"
     CDS             complement(40617..41078)
                     /locus_tag="VQT45_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET2358649.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(41075..41596)
                     /locus_tag="VQT45_000251"
     CDS             complement(41075..41596)
                     /locus_tag="VQT45_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HET2358650.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(41572..42543)
                     /locus_tag="VQT45_000252"
     CDS             complement(41572..42543)
                     /locus_tag="VQT45_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HET2358651.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGKSSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(42540..43334)
                     /gene="racE"
                     /locus_tag="VQT45_000253"
     CDS             complement(42540..43334)
                     /gene="racE"
                     /locus_tag="VQT45_000253"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HET2358652.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIYVEHVEL"
     gene            complement(43541..43789)
                     /locus_tag="VQT45_000254"
     CDS             complement(43541..43789)
                     /locus_tag="VQT45_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HET2358653.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(43931..45556)
                     /gene="treC"
                     /locus_tag="VQT45_000255"
     CDS             complement(43931..45556)
                     /gene="treC"
                     /locus_tag="VQT45_000255"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HET2358654.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTGNGIGDFRGIIGKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCIGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKDINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(45734..47701)
                     /gene="treP"
                     /locus_tag="VQT45_000256"
     CDS             complement(45734..47701)
                     /gene="treP"
                     /locus_tag="VQT45_000256"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HET2358655.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGNDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            47886..48596
                     /gene="treR"
                     /locus_tag="VQT45_000257"
     CDS             47886..48596
                     /gene="treR"
                     /locus_tag="VQT45_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HET2358656.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            complement(48629..49432)
                     /locus_tag="VQT45_000258"
     CDS             complement(48629..49432)
                     /locus_tag="VQT45_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2358657.1"
                     /translation="MASLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFISVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKHLSVRKRAKDIARVFQDPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMAALVKLKLLLLDEHTAALDPKTSQMVMDLTQKIVEYHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(49445..49873)
                     /locus_tag="VQT45_000259"
     CDS             complement(49445..49873)
                     /locus_tag="VQT45_000259"
                     /inference="COORDINATES: protein motif:HMM:NF014684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2358658.1"
                     /translation="MKTEIGLVLRSTGDNIPMSEANGVNVNTMKIVGYMISTGLIALC
                     GSLFAQNDGFSDVTSGTGTIVVGLSSEVLIHDLTIGGRLLSIGIGAIVYRLIILNIYE
                     IPNLDQNLVRLFNAILLALVLFAPALQKRLKIRGLKLRNE"
     gene            complement(49882..50322)
                     /locus_tag="VQT45_000260"
     CDS             complement(49882..50322)
                     /locus_tag="VQT45_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2358659.1"
                     /translation="MNFVLSSLSEGLLWSIMAIGVYLTFRILDIADMTAEGAFPMGAA
                     IVVSQIQAGANPWLATLLALLAGMVAGLISGMLHTKMKIPALLTGIVTLTGLYSINIK
                     IMGSVPNLSLGDSATVFKQLASLGLTNEGAVFSLSLVCLLLVWF"
     gene            complement(50367..51272)
                     /locus_tag="VQT45_000261"
                     /pseudo
     CDS             complement(50367..51272)
                     /locus_tag="VQT45_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512061.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
BASE COUNT        15175 a        11736 c         9477 g        15288 t
ORIGIN      
        1 attaaaaggt taagtaattt ttccaaaata cagcactcat atagacagta tcatcaatta
       61 tagccattgg gattttttga ttgccaattc catgtatctc tacacatgtc ttcaatcgat
      121 tttgttgtcc tccaatttaa ttccttatat gctttgtctg catttgcata ataagttgca
      181 acgtctcctg aacgtcttgg aactatttta taaggaatag ggatcttatt aacactttca
      241 aatgtattta caagttgtaa tacactagtg ccttctcccg agcctaggtt atagatataa
      301 acatctgttt tttcagatac tttttctaaa gcttttatat gtcctattgc taaatctact
      361 acttgaatct tttatctcat ttttcccttt ttcaaataag ttatctactc tatgatcagt
      421 tatttccatt tcgtttacta acatgacgca gtcacctagc atcatatact ccaacttttt
      481 ttctgaaagt ttagcaaata ttggtaagcg ataatatagt atattgaaac tagaatagta
      541 cacctctact tctaaaacat tgttagaaat cgatttgact gtcctgattg atttgtccta
      601 ttattatttc attttactat actctgttaa ttcatatgag tttaaaccga tttcatcttt
      661 aacctcgagt aaagcagttt caaatatttg tttaagagtt tttgattctt tacaattaac
      721 cgacaaactt tctgataaaa tatgtacaac ttctgagact gaataaccta tctcctcttt
      781 agaattatat aaatctgtag ctccaccaat aatccaaaaa tactgatttt gtgaacctac
      841 aatatcctca ttttctacgg aacttccttg tatcgaacaa attttattta tctttaccat
      901 aatacttcaa cccttttagt gtcaaaagta aaccaattcc tgtcactgtt aagaatagtt
      961 ccataatctt gttcgaacca gtctttggta atttttgttt tacatctact atttctttag
     1021 atttattaat atgattttca gtttctctgc catctccaac tattttatag tttacttctt
     1081 ctgtcttatt atcttgttta ttgtcgatct tgtcattcat ttgtctatta tctttacttg
     1141 agttaaactc tccgttcttc tggttactat caattacatt atttgaatta gattgttttt
     1201 cctctttgtt tttttctttt tcgtttttat cacttaaatt atttgttaca attttgtaaa
     1261 gcccattctc cgttacaata ttgaaattac catcgctatc acgtataaca gattctttcc
     1321 catttgcatt agatttgatg aatgatatat acttaccgga taaattataa aattggttat
     1381 ttaaaacggt tattttaccc tttgaatcct caataacaat tccttcttta ccaccgaata
     1441 tactattctc tgagactact aaattatcac taactcgtaa taattcaata tttggttgtt
     1501 ctgtttcctt agaattatta ttaattacat tttttgttac agtaatatct gatacttttc
     1561 ctaaatattc tgcactatct tttgcaactc gtatcgcttt tgttttagga tcggcaatat
     1621 taaatatatt ttcggcgata accacctgtt tatttaaatc taataggtct ttagtgtttt
     1681 tatagctata agcatttact aaagctgctc cgctttctcg ataatgtaca ctctctcctt
     1741 taactttctt atcaaagcga tttcctttga ttaatacatc agtgaatcct gtaaaacgta
     1801 cacctgcata catcatgtta tcaaaatgat tatttaaaat tttaatatta gaggggttct
     1861 gtgtcgacaa tgtttgatag tgtgtgccaa ttgctgttac taattcccca gatttatcac
     1921 ttttgccaaa ataggaattt tgaatagtca cattttcaga ttttttccca tcatcattca
     1981 aggcataagg aaaacctttt ctagttaatg gttcaatctg aatgctctcc ttacttatga
     2041 tttgcccatc cttcatcgtt ttgggtaagg cttgcccaag aaaacgagaa ttatcaacta
     2101 atacattttt cgaacctgca atttgaatag catgcccttg ataactatcc ttgaatgtta
     2161 cattttttat agttacgtta tttgaattcc caatagcaaa tgcacctgaa gaatttataa
     2221 gtggtagatt ttttgcttta gttccttctt cattcaaagc accgttcata tcaatcgtac
     2281 caccagaata actaatatct tctgttgggc cccattctac ttgcgcacca tcatccgtaa
     2341 ataaacctgt cataaaaaca atggaagggt gattcttaat atttatacca tttagaattg
     2401 tagctttctc attcaattct aagtgtgtat gactttttaa aaaaacaatt tcttttacta
     2461 aataagttcc ttcaggaaaa tatacatttc ctccacctag cccttgagct gcagcatcta
     2521 ttgcatcttg aattgcttgt cgatcatcat gaatcccatc acctaccgca ccataatctt
     2581 ttacacttaa agcagtatct tcaaattctt ttttgataat tctgtcactt ataacatctt
     2641 ccttataact cttattttca ttagtagata ttactgtaga ttcaactgtt ctgttgtcta
     2701 attgtgaatt ggaacgaata gtaccattag agctgatact attaacactt aacgaattat
     2761 ctaaaccatt agtggttgaa ttagaggcaa tcatttcagc agaacgattt tgattaacag
     2821 ttggtgaatt atctaaatca ttagtgattg cattagaaga ctcttttgta gccatcggtg
     2881 aagaactagt aacaacttca tccgataaaa taccttggct tcccaaaatt gaaattgcca
     2941 atagtaccga gcaagtcccc acctttaatt tacgaatact gaatacctca ttaggaacaa
     3001 aatatttcat cagaacctcc aattttttta ctatttttaa caattgatta ttacttttct
     3061 taaaatagat agaatgacac cgctgtcatt atctttatca tatattttcc aaattgaatt
     3121 gtcaaggaat aacacaagaa aatattaaaa tttatactct tcggaaatct cttcaaacta
     3181 ggtcagtgcc gccttgccct aagtctaggt tactgacttg gtcagttcta tagtagactg
     3241 aaactataat agtacacctc tacttctaaa acattgttag aaatcgattt gactgtcccg
     3301 atcgatttgt cctattctta tttcatttta ttatatctac aacctcaaag cagggttttg
     3361 agctatctat ggccaacttc ctagtttgct ctttagcctt ccattcaaaa gtgatgctat
     3421 ctttcttagc ttgaatataa aatatcccat ttactatatt taaatttgtt gatatgttgt
     3481 aaattataaa tgaaagaaca aatatcttgt catacaagca ttcgccaggg atatttacat
     3541 gaatatcgct catatggcgg attgaaacta aaacactaca atatatttct taaatagacc
     3601 ttctataaaa gctagattta acctcgataa aaatagatgc agtgcttcta aaatactgga
     3661 atagggcata taggtaatcg tagacaagtg ttttatagat tgtctcgcgg gagatctaat
     3721 gatgtatagc aagcatcact aaacatatag aatatttgtg ttattataat gtcaatatgc
     3781 tataaattct atcatgcaaa agaatgacta gaacatgaaa gacaggcaca aaactttgaa
     3841 caatattctg aaaacaaaaa aagacgcgag tttccacaat ctcactcatg gaaactcacg
     3901 tctttcaaaa aatagggtga attaaaaact agaacaagac actagatttt ctaaatgatg
     3961 tctagtaagg attctaaatg ctacaccaaa ttgctcacat cttatttcaa accacgggac
     4021 tcccacaaga aaggaaaatc ctataaaaat tctctctctg aggagagaga ggcctcaact
     4081 acaggtgtaa actattatca attgaaaaca acagttttta cactcaatta gactttttag
     4141 ggacaggatc actttcgctt gactgtagtt tgtcattttt ttgataaagt tagcactttt
     4201 tcagaaactg ttttgaaagt ctcaatgata tagtctactt cttcatcgct taatttagta
     4261 tgaagaggga gggtaatttc attctcaaag aaggcatagg ccttaggata gttcgtcata
     4321 tcaaatccaa gattcttata ggctgtcaag agaggaagcg gtttgtagtg aacattactt
     4381 gcaattcctg ctttagccaa ttcttggatg atgaggttgc gttcttctag gcttgctcct
     4441 tctacacggg tgatgtagag gtggcgtgaa gattcgacag tttcagtctt gtgtgccaaa
     4501 ggatggatgc gagaacctgc aaaaccacta tcatagcggt ccacaatgtc cttacggcgt
     4561 tgcaacaaac ttggatagcg gtccaattgt accaaaccaa gtgaagccat gatatcggtc
     4621 atgttgcact tataggctgg tgtaacgata tcgtattccc atgaccccag ttgcatcttg
     4681 gcaagagcat ccttagtttg cccgtgaagg gaaaggattt ggaattcctt gtacatctct
     4741 tcgtcatcaa tcactggatt ggctttccaa gtcgcacttc caccttctgc cgttgtaaag
     4801 ttcttaacgg catggaatga gaaggaagta aagtcagcga tagaaccaga aggttgtcct
     4861 ttataagtag atcccaaagc gtgggcacta tcagagacaa tgacaatacg gttaaaggcc
     4921 ttttgccact tgcttgaagc ggtaaagaag tcacgttttt tctccacgac ttggaacaaa
     4981 cggtcataat cgcaaacaat ccctgcgagc tctactggga taatcacctt agttttctca
     5041 gtgatagctt gctcaagcag gtcatagtcc atctcaaacg tatctgcttg gatatccacc
     5101 atgacagggg ttgctcccac gtgcgtaatg acactacatg aagccgtata ggttatggct
     5161 ggaacgatga cttcatcacc aggtcccact tcaaaaacgc gtaaaatcaa ctccagagcg
     5221 gctgtcgcag agttgagaca aacagtctta ggtgtctgtg tgtaaagaga caagcggcgc
     5281 tccagttctt ttgttttagg acctgttgtg atccaaccag aacgcagggt atccgctact
     5341 tcagcaattt ctgcttctgt gatatcaggc ggtgaaaatg gaatattgta atttggcatt
     5401 gatttgctcc ttttatctgt actcattctc ttatgactac tttattttag taccttaaac
     5461 acggtttgaa acatgatttt gatgtcccca aagaaactaa actctcggag ataggcgagg
     5521 ttatagcgca tcttttcagg aagaacatgc tccacatagg cctgatcaac tgacagacct
     5581 ttctctgtca tttgactgat gatggtgtcc tcatccttgt agttgatgct ggctggagag
     5641 gtaattcctg cttgcaagag caaggttgcc atcatttcag tgctatactg ctctgtataa
     5701 cgtggcactt caggtcgtgt accgacaaag gacatctcac ctttaaggac attgaccaac
     5761 tgaggcagtt cgtccaaacg gacacgtcgg atgaaatttc caaccttggt aatacggcta
     5821 tcgttagcag aagtcaccag atttcctttt ttatccgcat ccgtcaccat ggtacggaac
     5881 ttccaaatct tgaaccgacg gttgtactgg gtcacacgct cttgcttgta aatcactggc
     5941 cccttgctat ccaacttgat ccaaatgctc aagatgagaa agatgggaga ggtcagaacc
     6001 agtaagacca aggccaaaac ccagtccaag caacgcttga aaatcagcga acccttcctt
     6061 ttagagacaa gctggtagta agactcaacc tcgcttgatt tcatttccac aggcaagtct
     6121 tcccatttca gcatgctgtt ctcctttgtt tttattatac tatttgtcaa cactttttgt
     6181 caacactttt cattatacca caaaatggaa aaggcggtga aaaaaatctg taatttgaag
     6241 gatttccttc tagtactcaa tgaaaatcaa agtacagctt tgagattgca gataaagctg
     6301 acatggttta aagagatttt caaagagtat aggccatggc ccctgcctgc aaactataca
     6361 tcttgtgata ggttcctccc agagccaaga gttcctcatg ggttccactc tcgataatgc
     6421 gtcccttatc caagacatag atgcagttgg cgtcttgaat agtagaaagg cggtgagcta
     6481 tagcaatagt tgttcggccc tgtctcatct tcgccagaga agcttgaacc aagctttctg
     6541 tttcagagtc aatattggct gtcgcttcat ccaaaatcag gattttaggc tggctggcga
     6601 ctgttctagc aaaggcaaga agctggcgtt gcccagtaga gaagctcgaa ccacgctcgg
     6661 aaacagggga gtcgtacccc tgaggaagtt cttgaataaa ggaatctgca tccacaaagg
     6721 ctgccgcagc ctgaacctgc tcatcactga tttcttggta catggcgata ttggacttaa
     6781 tagttccatg atagaggaag ggttcctgca agaccaaacc gatgtttttt ctcagctctt
     6841 cttgactgaa atccctgata tccacatcat ccaagagaac tctccctgac tggaattcat
     6901 aaaagcgcat gaggacattg ataatagacg atttccctga acctgtatga cctacaaagg
     6961 caatggtttc acccttatta acagagaaag aaatgtcatc cagaatcgga tgtttaccgt
     7021 catatgagaa acacacatgt tcaaagcgga tattgccttc ttggactttg gcttgcccat
     7081 tttcttgaag aggttcatag gtcctctcgt ctaccagggc aaagacacga cctgcagaaa
     7141 ccatagacgt ttgcagtgtt gaaaagtttt gcgtcacctc aatcaaaggg tcaaagaggc
     7201 ggttgatgta ctggataaaa gcatacatgg tcccggccgt tatcccgata gaaagaccac
     7261 gatagccaaa ataggccatc aagacagcat aacctagaag tttcaacaaa ctcatggcag
     7321 gtctcaaaaa gagggcatcc aaggctacag aacggttggc atagaccaag tgctcttggt
     7381 tgatttcatc aaattctgcc tgcaggcgct tctcttgatt aaaggcctgg attattctga
     7441 ttccctcgat gttttcagcc agcttgctat tgatatctga caagagactt ctggttttct
     7501 caatgatttt cactgatttt ttccgataga gattgaccaa aaggaaaatc aaggggagaa
     7561 agagcaagac taatgctgtc aaacgaaaat ccaataccaa catggtataa agggttgtca
     7621 gaaagatgaa aactgctgag ataaagctag ataaaatccc agaaaacata tcactaatcg
     7681 tctcggtatc gttggtcaaa cgagaaacga tagaacctgc tggcgtcttg tcaaagtaag
     7741 acatgcccag tttctccata ttggcaaagg catcccgacg aatatcccta acaatactgt
     7801 aagacacgcg cgcaaagaga agattgccga catactgaac tacagtttgt aggatgtaga
     7861 gaccatagta gaccagcaaa acggtaacgg ctagttggtt aagattgctg agatactggt
     7921 cgataaagtg ggaagccacg aggggtatga cacttttaat gaccgtcgtc gctaggagaa
     7981 aactgagtgc caaaaaggtc aggagtctat aaggcttgag ataagacatc aagcgcttca
     8041 atacagccca ttgttcttgt ttattctgca tcttcttctc ctttcatttc taactgctga
     8101 gactggtagg tttgggcata ccagccatcc atcgctagca agtcttcgtg cctgcctcgt
     8161 tcgataattt gaccattttg tagaactaaa ataaaatctg catggacaac agcactgagg
     8221 cgatgggcag ttataatggt tgtcttgtcc tttcgcgtct ccttgagatt gtcgataatc
     8281 gcatactctg tcttggcatc tacggcggat aaggaatcat ccaaaatcaa gatatcaggg
     8341 tttaaaatca tagcccgact catagccaac cgttgctttt gaccaccaga aagactgact
     8401 cctttttcac caatcagcgt atcaaatcct tgaggcatgt ctacaatatc ttggtaaact
     8461 cgggctagct tagtagcttc ctcaacctct gaaaggggca agttaggatt gccaaagcgg
     8521 atattgtcta ggattgaagt cgcaaagaga aactggtcct gaggaacata gcccatgaga
     8581 ctgcgaagtt ctgtcaaacg atagtcccga atatcgtgac cgtttagata aatggcaccc
     8641 ttatccacat cgtattcacg caagaggagc ttgattaagg acgttttccc agagcctgtc
     8701 tgcccaacca agcccagtgt ttgccctttt gccaaactaa agtgaatatc cgtcagtgtt
     8761 tcctcatttt caaaagcaaa gctgtcaatg gcatactcca aacgcccatt ttcaatacca
     8821 tccagaggaa actcagggtc ttgtacagga gattcctgag acaaaagatt ttcaatccgc
     8881 tggtaagaaa ccttccctcg ctgagtagta ttaaagagga agccgatggc cataagaggc
     8941 cagaccagca tatccaaata gctgataaag gtgactagat taccaactgt aatctgccct
     9001 tcctgaacca tcaaggagcc aaccaaaagc gttaaaacat aggacgaacc aacaaacaag
     9061 agaaccatag ggtcaaagag actatcatat ttcatggttt gcaggttctt ttggaaggtt
     9121 aattcattga ctgcctgaaa agacttcaac tcgtctgcct gataaccgaa agacttggtc
     9181 actttgatac ctgatacgga ctcctgtacc ttgttattga gttcagaaaa agcagcttgg
     9241 gattcgccaa aggccttatg agtctttctc cctaggcgac tagtcgcata ggccatgaaa
     9301 ggtaggggga gaatggcaac aagagtcatc tgccatgaga tgctaaagag catggtcaac
     9361 aaagtcacca gagccgtgat agaggcatcc accgcagaca tgacaccgcc acctgctaaa
     9421 cgagtcaagg cattgatatc attggttgcg tgtgccatca gatcacccgt ccgataggtt
     9481 tgataaaagg ctggcgacat ttttgtgaaa tgcttaaaca agcgagaccg catgatctgt
     9541 cccaagcaat aagaggtccc aaggatatac atacgccaca catagcgcaa atagtacata
     9601 ccaaaggctg caagtagcaa gtaaaatagg ctaagaagga ggtcctgctg ggttaattgc
     9661 cccgatgtga tggcatcaat gactcgcccc ataaccatag gaggaatgag attgagaacg
     9721 gaaaccaaga ccagggccac aatcccgact agataacggt gtttttctaa cttgaaaaac
     9781 caccagagtt tttgaataat ggacataaaa tccctttctg attgcaaatg gaaacctgag
     9841 gccaatactc aatgaaaatc aaagagcaaa ctaggaaact agccgcaggc tgctcaaagc
     9901 actgctttga ggttgtagat agaactgacg aagtcagtaa cctacatacg gcaaggcgac
     9961 gttgacgcgg tttgaagaga ttttcgaaga gtacaagacc ccaggttttt cttattcata
    10021 agttacgact gtaacagcac ccttgtcata ttcagcaata aagatattgg ctacattgtc
    10081 atgcccttgt ttgctgaggt tatcaagcaa ccactcttcg ctacgaccaa tcgattccaa
    10141 gacgtctact tgaatcacac cgtcagtcac aactggatac ttaggatttt catctcccat
    10201 ttgcacaacg atgagttgcc cattttgctc ttgcacagct cgtttgactt gcttcatctg
    10261 gaaaatccct tggctacgaa gtttgagggc tacatccgat gcagacaaac caactgaacg
    10321 acaggcttat gggtcaatat tcccattttt gataaggaga gttggcttac catcaatcaa
    10381 acgtttcaca aagtgaacat tgttgttgag ctatttgaga gtcaagatca gtttgattaa
    10441 aatttcgata taattaagtg tcatttgttc acatccacca gttcaattgc gtctgtctta
    10501 tacaattcga ctttctctaa caggtacttg tctggctcac ttccgtttag ggcacgataa
    10561 tagcgatctc ccaccttgat aagtgcgcca tctgtgtttg tggaagtatt aacatggact
    10621 tctgacttgt ctactcccaa atctttggaa acaacctcga tgaaatgaag tgaagtttga
    10681 aatttattgt tagaaacttg attgttttga taagtcgtga tgctgaccaa aagcatagct
    10741 aaataaggcc agagctgaaa tcatgaccaa ctcacgaaat ttggttcctt ttttatcatg
    10801 gtatgccttg aaagcaaaaa aaactgtcac agctaataga acaatcccaa agccaaccat
    10861 gataccattt tgctgaccga tttggctgag tacatagtca taagagtaga atttcatgta
    10921 ttttcactcc ctttcataaa atcattctta attataaacg aaagagagta atttttcaaa
    10981 ccatacgttg gggaaataga tctttttttg gtataataaa atctataatc tgaatgaaaa
    11041 aggtaacttt atgaaactta tctcatggaa tattgattcc ctaaacgctg ccctaactag
    11101 tgactcagct cgtgccaaat tgtcccaaga agtcctacaa accttggtcg ctgaaaatgc
    11161 tgatatcatt gctatccaag aaaccaagct ttctgccaaa ggacctacaa agaaacacgt
    11221 ggaaatttta gaagaactct tcccaggcta cgaaaacacg tggcgctctt cccaagagcc
    11281 tgcccgtaaa ggctatgctg gaaccatgtt cctttataag aaagaactta cacccactat
    11341 cagcttccca gaaatcggtg ccccttctac catggacttg gaaggccgta tcatcactct
    11401 agaatttgat gcatttttcg taacccaagt ttacactcca aacgctggtg acggtctcaa
    11461 acgcttggaa gaacgccaag tctgggatgt caaatatgcg gagtatttgg ctgaactaga
    11521 caaagaaaaa ccagtccttg cgaccggtga ctacaacgta gcccacaatg aaatcgacct
    11581 tgcaaatcct gctagcaacc gccgttcacc tggatttact gacgaggaac gtgctggatt
    11641 taccaaccta ttggcaactg gatttactga taccttccgc catgttcatg gcgatgttcc
    11701 tgaacgctac acttggtggg cacaacgcag caaaacttct aaaatcaaca atacaggctg
    11761 gagaatcgac tactggctca caagtaaccg tatcgctgac aaggtcacta aatctgatat
    11821 gattgactca ggtgctcgcc aagaccatac accgattgtc ttggaaattg acttgtaagg
    11881 attttctata tggactacaa tgcggtcatt cccgagtttc ttgtatcgaa tatcgaacag
    11941 tcccggtcct tctactgtgg tttactgggt tttaggattg aataccaacg ttcagaagaa
    12001 aactttctct ttctcttgaa gagtgtcaac taatgttaga ggagggaaca aaggatcaac
    12061 tagctgaact gacctacccc tttggtcgtg gagtcaatct ctcctttggc ataaaggatg
    12121 ttccaaaact ctatcaaaaa gtgatggagg caaactatcc tatttatcgt cccttgacca
    12181 aaagaaagtt tcgtgtcagt gatccctata tctatcctca taaatttgca gttttggatc
    12241 cagatggcta ttttttaaga tttagcgagt agaataataa aaattgggaa aagtctttaa
    12301 aagttagaaa aaggcatatt gtcaggtgtc taaaaacttg atagtatgcc ttttatgatg
    12361 gaaaaatctt ctaatactct tcgaaaatct cttcaagcca cgtcaacgtc gccttaccgt
    12421 aggtatataa tactgactct gtcaattcta tccacaacct caaaacagtg ttttgaggtt
    12481 gtggatagct tcctagtttg ctctttgatt ttcatttagt ataaatgtta gcttacaatg
    12541 gagtttttgt tcaccctctc ttctgtttgt tcgtttttta aaccaaaaca ctaacaaaat
    12601 agttgatttc taaagttatt tagtgtaaaa taaaaacatt ggctcaagcc tatttaaaat
    12661 tgaatatcgt tttacttgtt tatgtcgtga attggcacga cgtttctaca aggtgccgga
    12721 acacctaaca ataagtaagt cagcagtgag atatggccgt ttttgccatg cctatttggg
    12781 ggacttactt agagattaag taggtctttt ttgaatattt ttaatatttc ccttaattag
    12841 tgcggacggg aggtgaaatt atcctgtgaa taatttcagg aatccaggga atttcatccc
    12901 taatttttga gcccctagct ctttcatttc taggcttagg ctaaaatagt tccccgaact
    12961 attttactct caaaaatccc gtcatagaca ataacaagat tattgtctat gataccacta
    13021 caacgggaaa tatttgataa gactcgcttc gctcgtaata gttttatcaa atatatagca
    13081 ttagcaaaag ggatcactat agaaacattt aaacaacaag taaattaact tttagacttt
    13141 aggaggtctt atgaaattat tagaagagcg catcctcaag gatgggcata tcttgggtga
    13201 taacatcctc aaggtagatt cctttttaac ccaccaagtt gactttagct tgatgcgaga
    13261 gattggtaag gtttttgcgg aaaaatttgc tgctgccggc attaccaagg tcgtaaccat
    13321 tgaagcgtcg ggtattgccc cagccgtttt tacagctgaa gccttaaacg ttcccatgat
    13381 tttcgccaaa aaagctaaga acatcaccat gaacgaaggc atcttaactg ctcaagtcta
    13441 ctcctttacc aagcaggtga ccagcaccgt ttctatcgct ggaaaattcc tctcaccaga
    13501 ggacaaggtt ttgattatcg acgatttcct tgctaatggc caagctgcta aaggcttgat
    13561 tcaaatcatc gaacaggccg gtgccacagt ccaagctatc ggtatcgtga ttgagaaatc
    13621 cttccaagat ggccgtgatt tgcttgaaaa agcaggctac cctgtcctat cacttgctcg
    13681 tttggatcgt tttgaaaatg gtcaggtcgt atttaaggag gcagatctct aatgcaaact
    13741 caagaaaaac actcgcaagc agccgttctt ggcttgcagc acttactagc catgtactca
    13801 ggatctatcc tggttcccat catgattgcg acagcccttg gctattcagc tgagcagttg
    13861 acctacctga tttctacaga tatcttcatg tgtggggtgg caaccttcct ccaactccaa
    13921 ctcaacaaat actttgggat tggactccca gtcgttcttg gagttgcatt ccagtcggtc
    13981 gctcccttga ttatgattgg gcaaagccat ggtagtggcg ctatgtttgg tgcccttatc
    14041 gcatctggga tttacgtggt tcttgtttca ggcatcttct caaaagtggc caatctcttc
    14101 ccctctatcg taacaggatc tgttattacc acgattggtt taaccttgat ccctgtcgct
    14161 attggaaata tgggaaataa cgttccagag ccaactggtc aaagtctctt gctttcagct
    14221 attactgttc tgattatcct cttgatcaac atctttacca aaggatttat caagtctatc
    14281 tctattttga ttggtctggt tgttggaact gccattgctg ctactatggg cttggtggac
    14341 ttctctcctg ttgcggtagc tccacttgtc catgtcccaa ctccactcta ctttgggatg
    14401 ccaacctttg aaatctcatc tattgtcatg atgtgtatca tcgcaacggt gtctatggtt
    14461 gagtcaactg gtgtttatct agccttgtct gatatcacaa aagatccaat cgacagcacg
    14521 cgccttcgca acggttaccg cgcagaaggt ttggccgtac ttctcggagg aatctttaac
    14581 accttccctt acaccggatt ttcacaaaac gttggtttgg ttaaattgtc aggcatcaaa
    14641 aaacgcctgc caatctacta cgcagctggt ttcctggttc tccttggact gcttcctaag
    14701 tttggtgccc ttgcccaaat cattccaagc tccgtcctcg gcggtgccat gctggtgatg
    14761 tttggttttg tatctattca agggatgcaa atcctagccc gagttgactt tgctaacaat
    14821 gaacacaact tccttatcgc agctgtttca atcgctgcag gtgtcggtct caacaacagt
    14881 aatctctttg tcagcatgcc gacagccttc caaatgttct tctcaaacgg aatcgtcgta
    14941 gccagcctac tcgccattgt cctcaatgcc gtattaaatc ataaaaagaa ataagaaaaa
    15001 gaggtgcgag cctctttttt gtttatcaca aattgattat aaatacaatc aatcccaatt
    15061 cccatctaat tgaattggac ctatttcaaa ttctttaaaa tattatgttc caaatcgtta
    15121 atattatata agaatggtaa aatatcaaat gtttctcgta aattattctt agccttatac
    15181 caaccttgtc catcagtaat ccacataaac tcaacattag gaatagcttt aatttcttca
    15241 gcaatcattt tgtaagatct agccgtctca tttaattttg aaccacttcc tgaataaaaa
    15301 ttaacctcaa tcagataaag cacttgttca ttttttatga caaaatcaaa acgtttcaca
    15361 gtattcccat cattcgtaat agcagataaa tcgacagaaa aaatttcctc tatttcattt
    15421 tgttcaatct ctttaaataa attctctcct aaaatatacc cttcagcttc aagataactt
    15481 tgaacaatat tttccatcgc atctccagtc cgatttttgc gcccattagt atccatacca
    15541 acctcaacac ctgtaacgta gtcaactaaa tttgatacta aatgattttg caataaatca
    15601 aatatacctg atttttccaa aaacatagta tattcttcaa tactatagtt tcgtttacta
    15661 aaatcaaaat agaaatcttt tatcggatcc ttaacaataa tcgtatctct caaacgttta
    15721 gcaataagta gaggcacaac tttcaaaatt tctggataat tttgatataa gtctaaaaaa
    15781 tcctcttgta tatttttact accaataaga ctattcataa tatttagagc aacttttata
    15841 ctagatacat ttttataaac cttgggaaaa tctgtataat aagtccagtc agctactgtg
    15901 tcggtcatcg ttgacaacca ctcatcaaaa tttctagttt gtttcatttt ctgcctccaa
    15961 cctcttcctt gcaattttta aatattcttt ttcagcatcg atacctataa atcttctacc
    16021 taaccgcttc gcaacaacac ccgtagtgcc actaccaaca aatgggtcta gaatatagtc
    16081 accctcttta gtagaggcta aaataatgcg ttctaacaaa tactctggtt tttgagttgg
    16141 atgtttccca gcccattttt caactttctt tgttaaagaa cccgtccaga catctttcat
    16201 ttgttttcca tcattcaatt ctttcattaa atcataattg tagtaatgac gagctttttt
    16261 atcatttttt ctggcccata aaatggtttc agtagaatgg gtaaaataac gacaagataa
    16321 attgggggca gggtttgttt tctgccaagt aatattattc agaattttaa aaccttcttg
    16381 ttctaatgcc attccaactg agtatatgtt gtgcaaacta cctgaaatcc ataccgtccc
    16441 attaggcttc agaacttctt ttgctaggcg aatccattta cgattaaact catgtttttc
    16501 ttcgaatgaa gaaattttat cccaatctcc tttatcaaca gaaacaactt gtcccccaga
    16561 attagatatt ccaccattac ttaaaaaata aggtggatca gcaaaaatca tatccatact
    16621 ttctggtttc atttttgata agaacttgaa cgtatctgaa tgaacaagaa tcatcttatt
    16681 tttattgtag tatggttttg tcataagaac acctccatac ttatattcgt tatttttcat
    16741 aatttgtgac tataatttca gaaatttttc ctcgacttga agattttgct ccattagttc
    16801 gggtagcttc aacataatgt atattaaaat ccttatacaa ctcctctact aaagcactag
    16861 aagaatttga taacataaca taagctcctg tatcactcaa tctcttaaag gcatctctta
    16921 atcttacttg atctgcaaaa gagaatccct catgagtata agacgtaaat gcactcgtct
    16981 cagacaatgg aatatatgga gggtcaaaat acacaaaatc tcctgttcga acatctacaa
    17041 ttgccttttc aaaatctccc actttaattt ctagttgatt gttatttaga taaactgaaa
    17101 tagcagatat caattcctca tcaacaattt taggattctt ataacgtcca tatggaacat
    17161 taaattggtt cttagaattc acacgatata gaccattaaa gttcactctc aacatatata
    17221 gaatacgtgc agctctttgt acttcggaca tcatatctat tctttcatca cgatctgcag
    17281 aacgtaaatc taaataatat tcttttgaat tatattcctg atgaactttc aaaatttcaa
    17341 tcaattcttg aggattgtcc ttaatttgtt gatagcaatt tattagttca gcgttaaaat
    17401 cattaataac tgcatcttta ggagccaaat caaaaaataa agctccacct ccaacaaaag
    17461 gttcgaaata cctgttatag gttttaggca ttaattctct aataacaggc aataattgtc
    17521 ttttaccacc tgtccatttc gtgaacggtt gtaaagtaac tttctttatt tcttttatct
    17581 tcatgctttt aattatacca tagaaattaa aacacaactc ttgtattttc taccacatta
    17641 ctaaattttc tattttagaa ttaaatcata tcaatataaa aaaatgagta aggcaaatct
    17701 tataaattcc aaaattcacc tcactctatt aaattactct ttatatcctt acccgtcttt
    17761 cctcagacct ttggcctgtg acaaacatag taaaggttgc tttgcagaca tttctgccct
    17821 cttgattggt gatatccaca tccatcacac aggttgtacg accttgatgg acacattctc
    17881 ctttaatggt caatacatcg tcgagttttc ctgccttaag gtagttgata gaggattgga
    17941 gtgtcacccc atcaagtccc agcgagataa ccaccaaacc actgatttgg tcacatagtg
    18001 tgaatagata gccaccatgg gcattgccat agtagttgag cgacgagttc actactttgg
    18061 tcgtcaccac aacgtgacca tctctcattt tttcaatttc gtaattttca aaggcagata
    18121 tagcgtcaaa atgaaagtct ttcatcgttt cctcctgata tttcaaatga cactatgata
    18181 ctacttttta taggactgtg caaggagaaa gctcctagtc tagtaaaatt ccgacatgtt
    18241 ccacaaagcg cataaaggct gtctgccctt gttctgtctg cttgtagact cctgcatcct
    18301 caagtacacg cgcaaagata gcacccacag agtccttgac gattgcaagg gctttttctt
    18361 tatccgttag gtctggatgt tgggatttga gttggtctgc ccactcctga tgataatcgg
    18421 caactgtaac agcttctcct acaagatagc tagcgacttg ctctacttct tctttcagac
    18481 gtggtggcaa gattgccaag cccatgacct caatcaagcc gatattttcc ttcttgatat
    18541 gttggacatc cttgtgggga tgatagatgc catcaggatg atctgctgaa gtctgattgt
    18601 ctcgcaagac caagtccaac tcaaactgtc catcacgctt acgcgctatt ggtgtgatgg
    18661 tgtgatgcgg tgtcccgtct gtctctgcta aaatctgcac actagaatct gaatactgac
    18721 gccattcctg gaaaatctta tcagctaagt taatcaaatc ctctttggaa tccgaagtca
    18781 agcgtaggac agacattggc cacttgataa ttccagcctt gacctgctca aaaccagcaa
    18841 atcggaaggt cttttgcaag ggagccaatt ccataggaaa tacgtgacgg cctccctgat
    18901 aatgatcatg agttagaata gagcccccca caatcggcag gtcggcatta gatccagcaa
    18961 aatatcctgg aaactgctct acgatagcca acagacgttc aaaactctga cgactaatgg
    19021 ccatgggacg atgctggcca tctaaaaaga tacaatgctc attaaagtaa gcatagggcg
    19081 aatactggaa accccattcc tgaccaacca tttcaaaacg gataatccgg tggttgctgc
    19141 gagctgggtg gttgacccga ccatggtaac cctcattctc taaacaaagt tgacactgag
    19201 gataattact agcttgcacc aacttggcta ccgcaatctc tttcggatcc ttttcaggct
    19261 tagagagatt gatggtaatt tcaagttctc cataatcaga tggaacacga taaacgatat
    19321 ttttagcaat ggccttgagt ttgatgtagt catttttctg actgagttga taaaaatcct
    19381 ctatcgcttg ctcaggagag taggcatagg cttcccagaa gtcacgattg acctgactcg
    19441 gacaaggagt caccaagtcc atcaattcag taccaaggat ttcacgcgca gtctgactat
    19501 cctcaatcgt ctctaatcga acggcttcct caactagctg gtccttgagg tcaatcaatt
    19561 tatccagatt ggtctcaact tccaaaacac cttctcccac tcgtgccaaa acacgattgg
    19621 tcaggtagat tcgatccatt tcctcaaatg aactttcaga aatgacatgt gttacaaatt
    19681 tatctactaa ggtcactata gagcctcctt ttgactagtc aaggacgcga gtgccacctg
    19741 caacttcagc gatatagaag cttggagcgt atccaactac ttcctcgtag tgtttgccta
    19801 cagcttcctt aaaggcctca acagtatctt tttgaaccaa ggcaatggca cagccaccaa
    19861 aaccagcccc tgtcatacga gcaccgagaa ctccttcttg tgcccaagct gtgtgaacaa
    19921 gagtatccaa ttccaaacca gttacttcat aatcatgctc cagagaaacg tgtgacgcat
    19981 tcatcaaacg accaaatgtt tccaaatcac ctgcttgaag ggctgcttga gctttaaggg
    20041 tacgttggtt ttcaaacaca gcatggcgag cacgtttcaa acgattttca tctttaatca
    20101 gatagctata ttggtcaacg gcccactcgt ccaattcacc cagggtctga atatccaagg
    20161 caacttgcaa ttcttccact gctttttcac actcagcacg acgttcattg tatttagagt
    20221 ccgccaattc acggcgtttg ttggtgttca tgataacaac gacattgtcc ttcaaatcaa
    20281 gtggcaccaa gtcgtattct aaagtattgg tatctaagta aatagcacgt tggtcagccc
    20341 ccataccaat agcaaattgg tccatgatac cagagttgac tccgataaag ttattttctg
    20401 tttgttttcc gattttaacc aaatcgagac gctctagttt taaatcaaag agatgctctg
    20461 ccacgactcc tgtcaagagc tccaaggatg ctgaagaaga caaaccagca ccatttggga
    20521 tattcccata aacataaaaa tcaaaacctt tgtcaatcac gtgcccagct tcttgcaaga
    20581 aatgaaggac accttttgga taattggtcc agttgtgctc tttttcaaac ttgaggtcag
    20641 cgagaggcac ttcgataatg cccttgtcct caaagttagc tgagtagaaa cgcaagactt
    20701 ggtcgtcacg cttacgagct gcaccgtaag ttcccaagga aatagcagca ggaaaaacgt
    20761 gcccaccgtt gtagtctgtg tgttcaccaa tcaaattaat gcggcctggt gaaaagaagg
    20821 tttggtctgc ttcttgacca aaaacagcaa gaaagtcttt gcgaagggct tcagtagtaa
    20881 gatgttgtgc catatgaatt ctcctttgac tgtccgttaa gccaccttaa cgtataatcg
    20941 ttttctttct attgtatcca aggaattttc caagatcaat cctttttact aaaattttag
    21001 taaaatatca gtaaaaagaa gaaaaacatg atatactaac ctaatcaagg aggatttatg
    21061 gctaccttaa aagacattgc acagctagcc tctgtctcta tcgcgaccgt atcccgcgtc
    21121 ctcaatcgcg accagagcct atctgttaca gaagaaacca gacaccgtat tttaaccgtt
    21181 gctgaagagc tgggctacac caagcacctc aagacaggcg agtcccacaa acccaagcaa
    21241 aagattgcca ttatccaatg ggtcagcgaa caaggggagc tggacgacct ctactactac
    21301 cagattcgcc taggaataga aaaaagagcc caagagttgg actatgatat cttgcgctat
    21361 tttaatgacc atccttttac cttaagcgag gaagtgattg ggattctctg cattggaaaa
    21421 tttagccgag ctcagatttc tgcctttgaa gaataccaaa aacccctggt ctttctagac
    21481 agtgatacac tttctctggg gcatacttgt attattacgg atttttacac tgccatgaaa
    21541 caggttgtcg attatttcct cagccaagga atggaccgta tcgggattct aacaggcctt
    21601 gaagaaacaa ctgaccaaga agaaatcatt caggataagc ggctggaaaa tttcagaaac
    21661 tacagtcaag caaaaggaat ctatcatgat gaactggtct ttcaaggaaa ctttactgcc
    21721 cagtctggct atgacttgat gaaggaagcc attcagaact tgggagacca actcccacca
    21781 gcatttttcg cagccagcga tagtttagct atcggtgccc ttcgtgccct ccaagaagct
    21841 ggaatcagcc taccagaccg tgtcagcctc atttccttta acgacaccag cctgaccaag
    21901 caggtttatc ctcccctctc cagcatcaca gtttatactg aagaaatggg gcgagcaggt
    21961 atggatattc ttaacaagga agtcctccac gatcgcaaaa ttcctagcct gaccatgctg
    22021 ggaaccagac tgacattaag agaaagtacc ctaaatcaag aataggataa cataaaaaac
    22081 gaatagagtt ctaaaactcc tattcgtttt ttattcgatt acaatcatag acttaatggt
    22141 cttacgttca tccatatctt tgtaggcttg gtcgatatct tccagtttat aacttgaagt
    22201 aaagacgcga cctggattga tatcaccatc aaggacggct tttagtaaaa attgcttatc
    22261 gtatgttgta gcagaagctg ccccacctgc tacagagata ttttgcataa atgtcgaacc
    22321 aagagcacga ttattatagt gtgggactcc tacaaagccc atacgccctc cattatgaag
    22381 aacacctagc gcctgttcta tagcagcctc cgtaccaaca cattcaagtg ctgcgtctgc
    22441 tcctccaccg aggatttcac gcaccttggt aattccttct tgaccacgtt ctgcaacaac
    22501 agctgtcgca cctgactcca tagccatctt ttgacggtct tcatgacggc tcataaggat
    22561 aatttgtgat gctccacgca tcttagccgc gatgacagca cattgaccaa cagccccatc
    22621 accgataaca acaaccttgt cccctttttg aacatttgca acacgcgccg catgatagcc
    22681 tgtcggcatg acatctgcaa gagtcaaaag ggactggagc atcccttctg tatagtcaga
    22741 aggttgacca gggattttaa ccagcgccca gtttgcatag tggaagcgaa tatattctgc
    22801 ctgaaaatca ccccccaaat tattgccaat atgattgtcg caagaaccgt caaatccagc
    22861 aagacaggca tcacactcac cacatccatg tgtaaaaggg acaatcacaa aatcacctgg
    22921 tttcaccgtc gtaatggctt ccacagcttc ttcaacaatc ccaatcgctt cgtgtccact
    22981 atttttgtgt ccagctttcg tttctggatt acggtacctc cataaatctg aaccacaaac
    23041 gcacgcacga accacacgaa taatcacatc atccgcttct attatttgcg gacgttcaat
    23101 gctagcaagt ccaacctgac ctgcctttgt atatactgct gatttcattt aaaattttcc
    23161 ttccttataa agtttaattt tgagatttaa acgatttaaa gctgtctgta gctgagacaa
    23221 gcgctcctct aatttttgct tttcctcttc taaaatacca agcctctcct ctctcgtttc
    23281 atctcccttt tggtagagcg acatatagtc aactaaacta tctacagaga cacccgccga
    23341 acgaaaacac ttaataaatt ccagcgcttc gatatcctga tcttgaaaat cacgaatccc
    23401 agtagcagta cgagtaatcg gtggcacaag accaacccgt tcataatacc gaatcgtatc
    23461 cgctgaaatt cccaacaaat cactggcaga tttaatattc acacgctaac ctcctctcat
    23521 ttcattcact gaattcacgc tattctaact cacttatctt attatataac tttgagttga
    23581 ctccaagtca agcattttgt atctaatcga aaaattttta tcattaacaa tcatatatct
    23641 ggagtttata caatgctctt ctcttaccaa tttttgaaat atttaaataa taaagaaatt
    23701 actctattcc aaataagata gtacccaagt atttttcact tttttctaat gttgatgctc
    23761 ataactccgt tccaagtcac acacctttcg cttatgggtt tggtgagttt ctaggtcagc
    23821 atcaatttca atggtaatat tttgaaaacc acaatctttt aggaaaattc gaatagactc
    23881 tttacaagtt tccatatgtt ccatttcttt tagacaaaca tggacaatgg catttttttc
    23941 caaagcatcc atagtccaga gattaagctg attaaggctg gccacattgt ccaatcgctc
    24001 caggccactc tttacttgct tgatatcaag accttctggc acagcatcca agaaaatctt
    24061 gagtgtagac caaaaacgtg gaagggcttt tgaaagaata aagaaagaaa tgacaaggga
    24121 caaaagagga tctaggatat accagtccgt aaatcgaaga acaatcgcca tcaggataac
    24181 agctacccac cctagcgtat cttccagaaa atgcagactc agaatagact cattctttgt
    24241 ctttccctta ccaaccacca gactcgctaa cagattgata gtaatcgcaa taattcctaa
    24301 ccagagaatc ccctcatcat tgactggttg cggatgcaaa atcttcgtga cattttccaa
    24361 aatgactaga acagagcccg ttacgagaat cacagctgtt accaaggctc ctagcaggct
    24421 aaaccgctta tagcccaagg tgtactgatt gtcttcttca cgattggaga ttgtttctag
    24481 aaaagctgat attccaattg caatcgcatc tcccaagtca tgcacagagt cagcaagaac
    24541 agcgctagaa ccaaatactc cacctgcaat aaactcaaca atggcataag tcaaatttaa
    24601 gaaaaaagcc acccaaacag catattttgc cttcatattt ctcattcctt tgttataata
    24661 gatttatgaa caccttgttc attatcatta tccactaaaa ctcaaagaaa ggatagaagc
    24721 aaaacgtcag ctttattcag ttctgaacaa tttgccttaa gtgtccatat gactaacatt
    24781 gaccgccgta tcagcaaaac caaaaaagcc atctatcaag cttttataca acttttgaat
    24841 gctaagggct acgaggccac tactgttcag gatatcattg atctcgcaga tgtgggacga
    24901 tccacctttt actgtcacta tgagagtaag gagcttcttc tggaccagct ctgccgctac
    24961 ctcttccatc atctttttga aagagagcaa gccatttcaa ccgaggacta cctcgcccac
    25021 ctctttctcc attttcataa aaaccaagac catatcacca gtctgctatt ttccaaaaat
    25081 gactacttcc tccgtcaact ccataaagag ctagaacacc atgtctattc cgtgctagct
    25141 gataatttaa aagaagccca ccctaatctg cctacttctt acctccaaca cttggtcatg
    25201 tccaacttta tcgagacatt gacctggtgg ctcaaaaaag gtcaagattt cacagaccag
    25261 gaagttgtcc aattttatct agaccttctc attcctaaaa attgaatata gagtaaagct
    25321 tcagttgtct tatttctagg ttactgagtt ttttatcttt tcaacaacaa aagaggaccc
    25381 gccgatcctc tttttcatac tataaatcct tgattatcaa ctatatctgt tttaatcgaa
    25441 atctcaaaac agcactttca aacatctttt cctagttaag taaatcagta ttctgcttag
    25501 ctgccttgct ccattgatac caaccaacta gactgttaat gagataaatt agatatttcc
    25561 cttgaatttg caggctttct ccccaccaga gatagattga aaagacattg gtagccgccc
    25621 agaatatcca ctgttcacgg taaacagctg tcatgaggat ttgccctacc ccattggttg
    25681 catctgtgat tgaatcacga tagggacgat tggcaccaat agactgataa atgaagccaa
    25741 aggccaacca ccaaagcaca ctaatggaaa gatactttgt ccagcccttg ccgtccagtt
    25801 tacgcgcgac aaactcctgc ttttccttct taaactgtgc ctgataaatc caaactagaa
    25861 gtccaattgg ctgcatgact gtgaagtaaa gtgtcgtcag cacctcacca taaaagcctt
    25921 tctgtagggc caaaataagg taaataacag agttaatcaa gccaaaaaga taattacttg
    25981 ctcgaccttc cgatacaaag attacacaga taatccctgt caagctacaa atcatcccaa
    26041 tccagtcaac aatacgatgt tcgtaaacca actccagcca gagaggaaaa cttcctaaaa
    26101 ccagcaaata aatccactgg gcaaaactac gatgggcaaa gaggtcatcc cagatagcct
    26161 tcatagttcc tgaaaatcct aaatcagcca tagccgcaac catacgacgg taaccacctg
    26221 acatttcacc tagggttgtt ttgatatttt caattttctt ttgcaaataa gtatgcatca
    26281 tttctccttt tgtttttaaa gagccgtgtc tggatagact ttcggacgca acgctctatt
    26341 agataatgaa ctgcctatac acaagatttc taaccttagt cgacatgagc tgaaacctct
    26401 tatttgttaa gtagttcaca aaatattata cacctatttt atgaatagtc aactgtcttt
    26461 acagtaaaat tttagaaaat catgaaaatt ttctctttct ttccatttta agtgacattc
    26521 agtcattctc acatcaaaaa agcccagacg aaattgtctg agcattcttt tatctagtcg
    26581 tttaaggaag ttgagttcag tatgtttaaa gtctctgtcc catcatttct tcaacaaacc
    26641 ttgttcttgg agaaactcct tggctacttg ctttgctgac ttgccttcaa caccgacttg
    26701 gtagttgagc tggctcatct ggctttctgt aatcttacca gccaatgtat taagaactct
    26761 ttccaactct gggtgtttct tgagaagagc ttctttcatg agtggagccc cttgataagg
    26821 tgggaagagt tgcttgtcat cttccaagac ctgtaaatca taacgctcca attccgcatc
    26881 agtcgaatag gcatccgtga tttgaatatc ccctgactga atagcctgat agcgaagggc
    26941 tggctccatg gtcgctacat tgagattgag accatacatt gattgcaagc ccttatttcc
    27001 atcttcacgg tcgttaaact cgagtgtaaa acctgccttc aactgccctt ccactttttt
    27061 caagtctgaa atggtcttca agccatattc ttgagcaatc tttttcggaa cagctacagc
    27121 ataggtgttt tgataagaca tgggtttgag ataggctaga tgatcctgct tagcaatgcc
    27181 atcacgcgcc acctgataaa cctgttctgg ttcatgactc accttgggtg atggttgaag
    27241 caaactttca gtcaccgtac cagtaaattc aggatagatg tcaatatcgc cttttttcag
    27301 agcttcataa aggaagcttg tcttcccaaa attcggttta acagtcgcag tcatgctggt
    27361 attttcttca atcagcaact tatacatatt ggccaaaatt tctggttctg gacctatttt
    27421 cccagcaata accaagtttt ccttctcttt ttgaaccaaa agagctggac tataagacag
    27481 acccagtaat aaagccacca aggcaaaacc tgagaaaatc gtccgtaatt ttgctttttc
    27541 catcactttt agtaggaagt taaaggcaat ggctagcact gcagaagaaa gtgccccaat
    27601 caaaatcaaa ctggcattat tacggtcaat tcccaaaaga ataaaggaac ctagtccccc
    27661 tgcaccaatc aaggccgcca aggttgccgt accgataatc aaaacagctg ccgtccgaat
    27721 cccagacatg ataacaggca tggcgagtgg aatttcaaat ttcttgagac gttcccatct
    27781 ggtcatccca aaggcaatcc cagcctcttg caggttcgga tcaattccct tcagcccagt
    27841 gatagtattt tgcaaaatag ggaaaatcgc ataaatcact agagctgtca aagccggcaa
    27901 ggtcccaatt cccatcaaag ggataaagag ccccaacaag gccagagacg ggatggtctg
    27961 gaaaatacct gcaatctgca agacccagtc ggccagcttc tcatgatagc gaagaaaaac
    28021 agccaaggga atcgcaagca aaatagctag taacaaggtc aaaagcgaca actgcaaatg
    28081 ttgagataga gctgtcaacc aatcactaaa acgatcctga aaagttgcaa ttaaattagt
    28141 catgaacact acctccaaac aagtctgcta caaagtctgt tgcaggcgct tttaaaattg
    28201 tctcgggatt cgctacctgg cgaatttctc catcctgcaa gacagcaata cggtccgcca
    28261 acttcaaggc ttcatccgta tcatgggtta caaaaatcgt tgtcatccca aactctttat
    28321 gcaattcttt tgtcagaacc tgcaactgtt ttctcgaaat agcatccaag gccgaaaagg
    28381 gttcatccat gaggaaaatc ttgggctgac caatcatagc tcggacaata ccgacccgtt
    28441 gctgttctcc accagataat tcactaggta agcgatgccc atactcggct actggtaaac
    28501 caaccttagc caaaagctct tctgttttct tcgtaatttc ttccttgctc caccccttca
    28561 tttcaggaat gagagcaata ttttccgcaa ctgttagatt tggaaaaaga gcaatagcct
    28621 gtaaaacata accagtagaa agacgaagtt cacgctcatc atagtctttg atgcgcttcc
    28681 catccatata aatatttcca tcagttggtt ccaaaagacg gttaatcatc ttgagcatgg
    28741 tcgtcttacc tgacccagaa ggccctacta aaaccataaa ttccccatcc tcaatctgta
    28801 agttgacatc tctcaagaca tccttttctg tgtagcgcag tgctacattt ttgtattcaa
    28861 tcattctttg tcctcaattt aaaacttccc tcgattggtc aagtcttcta ccttaggcat
    28921 aacttcctta ttatcccaat gctccacaat tttcccgttc tctaaacgga agatatcgta
    28981 ctgggcataa gcaacgccat caatctgagt ctgaccatag ctaaccacat agtttccttg
    29041 tcctaagagt tggaaaacaa agtcaaaagt gacactatat tcagccacat agtttttata
    29101 agcagcactt ccttgtccaa tatcatgatt atgctgaatc aaatcgtctg ccacataatc
    29161 actccactgc tctagctccc cattttggaa aatttctgtc aagaaacggc gaaccagctt
    29221 tttattttct gctttcttgt ccaaatcctt gatttcaaaa tctccaaaaa tttgatctag
    29281 ttggtcattt tcaggtgttc gatagtagtc aacgacatcc caatgctcaa caatacgacc
    29341 attctcatcc gcacggaaag tatccgtcgt cacccattga gcttctccac cattcagata
    29401 ttgatgaaca tgaacaaaga ccagattgcc atcctcaatg gtgcggacaa tcttaatctg
    29461 acgctctgga tgacgctcaa agaaatctgc aaagaaggct gcaaatcctt ctttcccgtc
    29521 aggaacacct gtcgaatgtt ggatataggt atcccctaca gactgggctt gagcctcagc
    29581 aactcgcccg tcttgaatgg catggatgta taggttgtga gcatttttca cttgttgtga
    29641 catattctaa acctcatttc ccttctcttt cagattcgcc aaaattcttt cttgaaaacc
    29701 ttcaaattgg tgaatttctt cctctgaaaa tcctttgtaa aagatagtat ccaatttctg
    29761 actgacacga tgccccactt ctttctggaa cttgcctaac tccgttaaaa ctaaatactt
    29821 cttacgcttg tcttttccac acggactaac aattacaagc ttttgttcct ctagcttttt
    29881 tatcatagtc gtcagcgtat tattcgcaag cccagtcgca agcgcgatat ctgtcgcagt
    29941 tgcgcagcca gtttcactat tccataaaac cgctaaaatc ttgccctgtt cacccctata
    30001 aagagcctca ggatcttgac tcagtaactt ttgaaaaatc cgcccattca acaaacgaat
    30061 atgatgggct agcaaatgac tatctttcat aacacctcca atttatttcg atatcgaaat
    30121 gaataaaata attgtaacac tcatcgttct aactgtcaac tatttcgatt tggaaataat
    30181 ttttgataat tatccacacc accatactcc ggctcaacta acttttaacg agagtttcta
    30241 aactccttcg tcctccagtc tacaaaagcc ttccattcgt actatcctat attttatgag
    30301 gggacacatt tttcctatca gaccatttat tttaaagata gaagtaaatc ataattgctt
    30361 ccatctgttc ttttatagta tattgaagtt agactagagc actgtatctt ctaaaacatt
    30421 gatagaaagc gatttgaatt tcccaatcaa tttgttcgta tttatagcat tttgaaacta
    30481 gaataggaca ccatgactgc taaaagattt ctataaattc atttgatttt cctaatcaat
    30541 ttgttcatat cttatttcat tccgctataa tttcacctta ccctatcttt ttcgtagcac
    30601 ccttcaaaca gcctatcccc taccgtttga cgattcctca cttcgctcca cttccattac
    30661 agaagtttct tcactactat gggctcggct gacttctcat gattccttgt tactactatt
    30721 tgaacgctca cgagatagat cttacaaaaa atgctttgat ccacaatgga atcaaagcat
    30781 tttaaagagt tcctcataca taagcgcaga agtcgcagtt cctctgtact tggcttcttc
    30841 tcttttgata aagcgagcca agttgagcaa ctcaggtgct ggatgtttgg gatttaggag
    30901 caattcacga ttgaccaggc ctgagagacg aactgcctgc aattgctcat ttgtagtagg
    30961 cagtttttta gcagtctcta ggagagcagc aactaaatct tcactcaaat catgtcgagc
    31021 atgattgtaa agatctttta taaggctttc taggtttggt tctgccatcc ctaccacctc
    31081 ccttatggtt taataatgtt taatcaaatc aaccgttgaa cgatccaatt tcttcaccaa
    31141 ggcttgtaag aaagcttgcg cttctaggaa gtcatccatt gcatagaggg tttggtgaga
    31201 atggatataa cgagcgcaga caccgatagt tgttgatggg acaccaccat ttttcagatg
    31261 agctgcacct gcatctgttc cgcctttacc acagtagtat tggtacttga taccagcttc
    31321 ttcagccgtt gtcaaaagaa aatccttcat ccctgggaga agcaagtgac ctggatcata
    31381 gaaacgaatc aaggttccat ctccaatctt gccttgacca ccgtagacat cacctgctgg
    31441 tgagcaatca actgcgagga agacttctgg gtcaaacttg gttgtagagg tatgagcgcc
    31501 acgcagacca acttcttctt ggacgttaga acccagatag agttcattgc cgagtttttg
    31561 acctgataaa gcttcagcta gctcgcttac catgaggaca ccgtagcggt tatcccaagc
    31621 ttttgagatg atattttttt cattggctgt caaaattgca gaactatctg gtacgatggt
    31681 atcaccagga cggatgccaa aactttctgc ctcagccttg tccgcaaaac caccatcaaa
    31741 aacgatatcg gcaatggctg gcatggttgg tccccccttt ccacgagtca aatgcggagg
    31801 aacagaacct gaaatcacag gaatttcatg accatcacga gtcaagagtt tgaaacgttg
    31861 gctgctaacc accatggggt tccagccacc gatttctacg acacggaagg taccatctgg
    31921 cttgatttcg ctgaccataa aaccaacttc gtccatatga gaagcgacca agacgcgcgg
    31981 tgcatccaca gcttctgaat gtttgatacc aaaaatacca cccaagccat ctgtcaccac
    32041 ttcatccaca tgcggtgtca acttttcacg aagataagca cggacaggcg cttcatgacc
    32101 tgagactgca gcaagttctg ttacttcttt aatttttgaa aataatgttg tcatttcagt
    32161 tccttctttc tttcatccat tttaccactt tttataggag aaggatagtg ggaaggtgga
    32221 tttctaagtt agtatcttag tcctgctcta tcttagaaaa ggatagtatt ctcttgcatg
    32281 tagtgcaaaa tctagtaaac attccaaaat taactcgaat atttatttcc aaacaaaaaa
    32341 acaatacacc atcaaagttg tttgtatttt tcatgaaatt tacagaaaat agttgacttc
    32401 cctttcttct ttctttaaat atatagttgg ttgagtttgg aatagtacgc tgtagctgct
    32461 gaaacatttc tagaaattaa tttgactttc ctaatagagt tgttcatatc ttatttcaat
    32521 ttactatagt acaaaactag aaaaggaaaa aatcatgacc aaaacaattc ttgttacagg
    32581 tgggactagc tacattggct cccataccgt taaagctctt ttaaatgctg gctataaggt
    32641 gcatgtcctc gataatctct ccacaggaaa tcgagcggct gtggatagtc gtgctagctt
    32701 taaagaactg gatgtttatg atgctagcgc cttaaaggct tacttagaag aaaatcagat
    32761 tgatgctgtc ctccattgtg caggtgaaat tgttgtgagc gaaagtattg aaaatccaag
    32821 taaatacttc actgccaacg ttgctggtat gaaccaagtt ctcaaagtct tatctgaagt
    32881 tggcattcaa aaaatcatgt tctcttcgac tgcttctctc tatggaaata actgtattga
    32941 caagccagtg actgaagata ccctgctcga ccctgtcaac ccttatgcag agacaaaact
    33001 gatgggcgaa cgaatgattt actggatggc caatcgctac gactggaaat atgttatttt
    33061 ccgttacttt aatgttgctg gggctgaaat ggatgcttca aacggtctgc gtgtgaaaaa
    33121 tccaactcac atcattccaa atatcaacaa gaccgcattg ggacaaaatg atagcttaaa
    33181 aatatttgga gatgactacg atacacgtga cggttcatgt attcgagatt acatttatgt
    33241 cttggacctt gcataggctc atgttaaagg aatgaactac ctatttcaag aagacagttc
    33301 ttctcaaatc tttaacttag gaactaaaaa aggctatact atcaaagaaa tctttaaaac
    33361 tgctgaagaa ttactaaatt aaaaaatccc acacgagatt gttgctcgac gtgctagtga
    33421 cccagccagt gtcctagcag atgcttcaaa agctaaacaa tatcttgatt ggacggctag
    33481 ctactccctc gaagatatta ttttatcaga ttaaggtaaa aacattttag aataggataa
    33541 caaaggagaa agtcttgttg ctctctcctt gttgtattta ttaaattgtc agaaatttta
    33601 ttgacagatt agaaaaataa tgttacattt atatccgcag atatctttcg ataccaaatc
    33661 tacatgaaag gacggggtat gaaactttct cattatttaa ttggcttact tctactccta
    33721 gtctttctct ctattagcat tgggaccagt gatttttcat ggggaaagct atttgatttc
    33781 gaccagcaga catggctcct ctttcaagag tcccgtctcc caagaactat cagtattctc
    33841 ctgactgcct ctagtatgag tatggcaggc cttctcatgc agactattac ccaaaatcag
    33901 tttgctgcac cgagtacagt tggaacgact gaagccgcca aactgggaat ggtgctgagc
    33961 ctttttgtct ttccatcggc tagtctgacc caaaagatgc tcttcgcttt tgtttcatcc
    34021 atcgtattca ccctcttctt cctagccttt atgaccattt ttactgtaaa ggaaaggtgg
    34081 atgttgcctc tgattgggat catctatagc gggattatcg gctcagtcac agaagttatc
    34141 gcctatcgtt tcaatctggt tcagagtatg actgcctgga cccagggctc cttctccatg
    34201 attcagaccc atcagtatga gtggctcttc ttaggcctca tcatcctgat aaccgtttgg
    34261 aaattatccc aaaccttcac catcatgaat ctggggaaag aaatcagcga gagtttgggg
    34321 atttcctact ccctacttga aaaactggcc ctctttctgg tggcgctaac gacaagcgtc
    34381 accatgatta ccgtgggtgg cctaccattt ctcggagtta tcgttcccaa tcttgttcgc
    34441 aagcgctatg gagataatct aagtcaaacc aaactcatgg tcgcactggt tggtgccaat
    34501 ctagttctgg cttgcgatat cctatcccga gttctgatta ggccctatga gttgtctgtc
    34561 agtctcttgc taggaatcat cggtagtctc ggctttatcc tacttctctg gagaggggga
    34621 cgaaaagatg cagactaaaa gcaaacatac caagctcttc tggattctca ttattcttgc
    34681 catcggagct tgtcttctct acttttggcc catcactcac ttgtcagcct ttgcttggaa
    34741 gttgcgttcc caaaagatca tcgtttatct cttggtagcc atcgcgactg ggatttcgac
    34801 cattagtttt caaaccctga cggaaaatcg cttcctgacg cctagtattt tgggaattga
    34861 atccttctac gtcctactac aaaccctact actggttttt gaaagcaagt ttcttcaact
    34921 tggcaaatcc cctatcttag aattcctagt cttacttctt gtccagtccc tcttctttct
    34981 caccttacaa ggttacttga agacactgat gaagcaagac ctggtcttca tcctgctgat
    35041 ctgtctagcg ctcagaagtc tctttcgaaa tatcagcacc ttccttcaag tcctaatgga
    35101 tccaaacgaa tacgataaac tgcaaaatag tctttttgcc tcctttcaac atctcaacac
    35161 ttccatccta gccatcggtt ctctgatcat cctcgctttg acaatctttt tctttcgaaa
    35221 agcagtcgtt ctagatgtct tgcacctgca aagagaaacg gctcagatat tgggactcga
    35281 tgttgaaaaa gaacagaaag agctcctctg gggaatcgtg cttttgacct caacggccac
    35341 tgccttggta ggacctatgg ccttcttcgg ctttatgctg gccaacctca cctacctgat
    35401 tgtcaaagac tatcagcaca agttactctt tatagtggcc attctggttg gatttattag
    35461 cttaaccttg gggcaagcct tgattgaacg agtctttgca ctggaaattc gtatcagtat
    35521 gatcattgag agtgtgggtg gcttcttatt ctttatctta ctatatagga ggtctcgtca
    35581 gtgaaactgg aaaacattga caaatccatt caaaaacagg atattttgca aggcatttcg
    35641 cttgaagtca gtcctcaaaa actgacagcc tttattggtc caaatggtgc tggaaaatcg
    35701 actctcctct ccatcatgag cagactaacc aagaaagatc agggagttct cagtatcaaa
    35761 ggacgtgaaa tcgagagctg gaattcgcaa gaactggccc aagaactaac catcctaaaa
    35821 cagaaaatca attaccaagc caaattgact gttgaagaac tggtcagttt tggacgtttt
    35881 ccctacagcc gaggtcgact tagatcagaa gactgggaaa aaatccgaga aactctgaac
    35941 tatttggaac tgaccaactt aaaagaccgc tacatcaata gcctgtcagg ggggcaactc
    36001 cagcgcgtct ttatcgctat ggtactggcc caggatacgg actttatctt gctggacgaa
    36061 ccactcaaca atctcgatat caagcaaagc gtcagcatga tgcagattct tcgacgactg
    36121 gtggaggaac tcggcaagac cattatcatc gtcctccacg atatcaacat ggccagtcag
    36181 tatgcagatg aaattgtcgc cttcaaggac ggccaggtct ttagcaaggg aagcaccgat
    36241 caaatcatgc aggctgacct gctcagtcaa ctttatgaga ttcccatcac gctagctgat
    36301 atcaatgaca aaaagatctg tatctatagc tagtaacata aaagctcaag ttagagaacc
    36361 ttcagtctct tagtcaataa gattaagaga ctccctaaat cgttatcaca ttttaaaaag
    36421 gagaaattat gaaaacatcc cttaaacttt atttcactgc cctagtggcc agcttcttgc
    36481 tcctacttgg tgcatgtagt acaaactcaa gcactagtca gacagagacc agtagctctg
    36541 ctccaacaga ggtaaccatt aaaagttcac tggacgaggt caaactttcc aaagttcctg
    36601 aaaagattgt gacctttgac ctcggcgctg cggatactat tcgcgcttta ggatttgaaa
    36661 aaaatatcgt cggaatgcct acaaaaactg ttccgactta tctaaaagac ctagtgggaa
    36721 ctgtcaaaaa tgttggttct atgaaagaac ctgatttaga agctatcgcc gcccttgagc
    36781 ctgatttgat tatcgcttca ccacgtacac aaaaattcgt agacaaattc aaagaaatcg
    36841 ccccaaccgt tctcttccaa gcaagcaagg acgactactg gacttctacc aaggctaata
    36901 tcgaatcctt agcaagtgcc ttcggcgaaa ctggtacaca gaaagccaag gaagaattgg
    36961 ccaagctaga caagagcatc caagaagtcg ctactaaaaa tgaaagctct gacaaaaaag
    37021 cccttgcgat cctccttaat gaaggaaaaa tggcagcctt tggtgccaaa tctcgtttct
    37081 ctttcttgta ccaaaccttg aaattcaaac caactgatac aaaatttgaa gactcacgcc
    37141 acggacaaga agtcagcttt gaaagtgtca aagaaatcaa ccctgccatc ctctttgtca
    37201 tcaaccgtac ccttgccatc ggtggggaca actctagcaa cgacggtgtc ctagaaaatg
    37261 cccttatcgc tgaaacacct gctgctaaaa atggtaagat tatccaacta acaccagacc
    37321 tctggtatct aagcggaggc ggacttgaat caacaaaact catgattgaa gacatacaaa
    37381 aagctttgaa ataagccact tcaaactcaa tttaatactc aatgaaaatc aaagagcaaa
    37441 ctaggaaact agccgcaggt tgctcaaaac actgttttga ggttgcagat gaaagctgac
    37501 gcggtttgaa gggattttcg aagagtataa aattttgaca ttctaaaacg catcctatca
    37561 agttcactca aacctgatag gatgcgtttt tatcattttg aaatctattt accccacctc
    37621 attccccttc ttgatttcgt ttaagggaaa agtggtctgg aacggggtcc ttacctgttt
    37681 tcgaccaggg atgacaacgt aaaatccgag ccaagcccat caataccccc ttaaaaccat
    37741 gtttttcaat agcctgaatc atgtagttgg aacaagtcag ctcaaagcga caagagggtg
    37801 gaaagactgg tgagataaaa cgttggtaaa agcgcacagg cgctattaaa attcgtttca
    37861 ttatttctta gttacagcca tggtgtgtag ttggctgatt tcttttttat taagacgacg
    37921 ggattctcct ggacggagtc ctgtcaagtc taggtgtccg aaacgagtcc gagacaactt
    37981 atctacttgg agaccaacag cttcaaacat ctttttaacc tgatggttac gcccttcatg
    38041 gatggtcaac tgcaccacag agcgattttt gactgggtcc actttgagaa tttcataaac
    38101 agctggcttg gttttcttac catcaatctc aagaccacgg gtcaaggggc ggagattgtc
    38161 cttattggcc acacccttaa cacgcgcgac ataaaccttg tcaatctcat tacgagggtg
    38221 aatcatctcg tctgtaaagt ccccatcatt ggtcaaaatc aagacacctg atgtatccca
    38281 gtccaaacga cccacagggt aaatacgctc tttgacattg ggcaagaggt cgacaaccgt
    38341 cttgcgaccc ttatcatctg tcacactgga aatcacaccg cgtggtttgt taagcagata
    38401 gtagaccttt tcttcgttgt agataggttg accttcaact tcgaccttgt cgcctgactt
    38461 gatagtggtt gctagttcac gcaccacttg gccgttaacc gtcaccaagc cttgcttaat
    38521 cagctcttct gcttttctcc tactggccac acctgcgtgg gcaatatact tattgattct
    38581 catcttcttc tatcctttca ccaaataatt ggctttcttg ggcttgaatc tcaagctcat
    38641 caatcactgg taattcttct aaatggttta tccccatgta atctaggaaa taatccgtag
    38701 tcacatagag gttggggcgc cccaatactt cctttttccc gtcttccttt atcaggtcaa
    38761 aagcctgcaa ctttgccaag gctccactcg agttaactcc acggatggca tcaatttcta
    38821 tccgcgtaat cggctgtttg taggcaataa tggacaaggt ctcaagggca gcccgagaca
    38881 agctctggtt gataggcgcc ttagagtatt ccttcaaaat ctctgcaaat tgagacttgg
    38941 tcaccaatct ataagcacca cttgtctcaa tcaaagccaa actggaatct gggtcctttt
    39001 catacttctg ggctaatttt cctaaactct gctggatgcc tgtcggtggc agagagagga
    39061 gttcagctaa ctggcggacc cgaatcccat cttcacccgc tacaaacaag agcgcttcta
    39121 tttttgctaa agtactcatc tttcctctct atcaagtcta gctttgaggc acttgacttt
    39181 cttccttctt ttccatgaga tagatatctc caaaactctc ctcttgcacg aggatcagct
    39241 cctgggtttt gattaactct agggttgcca aaaagagggt gatgacctct tggacattct
    39301 gggcttcctt gaacaaatcc tgcaagcgca attgatctcg tccaatcaag gactctttca
    39361 cgataatcat catgtcctca atcttatact catcccgcaa gatagtcgtg tgattttgtg
    39421 caaactcctc ttttttcttg gctaggatat ttgaaaaagc caaaaagagg tcaatggtcg
    39481 tcttgtcatg cacaagctcc gcatcttcgt aaatcaactc tgtcggcgct ttggaataat
    39541 actgggcccg ttcttggtgc ttggcttcca agtgctcacc caagagcttg aacttgcgat
    39601 attcttcgat ttgagagagg aggtcctgct ccaggtcatc ccccaagtct gtcacttctg
    39661 ctaccttcgg aaggagttta cgactcttaa tcagcatgag ctgactagcc atgaccatgt
    39721 actcacccgt cacttccaga cgcatggcct gcagggttga aacataggct agatactgtt
    39781 cgatgacttc cgtaatgggc acatcgtaga tatccatctg gtacttagaa accagatgca
    39841 agagcaagtc cagggggcct tcaaaatctt ttaatttaat atccattatc tatatttttc
    39901 taaggtcagg actgttttta atcctaattt ttttgcaatt tcgtacaaat cgaccttgtt
    39961 ttctatttgt cttagaataa actgttcacg taagacttga gctgataagg atggaaaacc
    40021 tttctccttg acaaaagatt ctaactgacg aaaggcccac tgacgagaat agggtttctc
    40081 tcctctttca aaaagatagg tctgccccat caagggttcc aattctgaaa gcaaggccgt
    40141 gggaatggtg acaatcctct gttgggaagc cttgctgatt cgcaacacct gaaaatccag
    40201 attgatgtcc gcaaccttga tggctaaaat ctcactgggc aagagcccca tttctaggat
    40261 taagagcgct agcaagcggc cctctggatg gtcgctttcc tgccaaaaag agtctaggta
    40321 tagaatctct ggcttttccg tcttcttttc agcttgtttg gctaattcca agcggtaaaa
    40381 gctgtccacc tctccttttt gatagagaaa gtatagaaat tggttacagg ccgaaatctt
    40441 tcgcttctgg gcgctgattt ttagattggc tagctgggct tggtaaatct tgagactggt
    40501 ctcagaaatc cgctcaccta ccatgtctaa aaattgctcc aaatcatact tataggactg
    40561 cttggaattg acagacaagc cctgcttttc ctctaaaaag gctgaaatcc tgtctctcat
    40621 tggcatcgaa tctcatattc cttactaaag tcatgcaaga gggcattaac ggccttgagg
    40681 atggacttac gcgtaataat cccttggaaa ataccctctg catccacaac cggtaagaag
    40741 gactcatcta ctagcttgtg caagacctcc gtaatggtga aatcaggcga aacaaccgct
    40801 acgtccgttt ttgtcatatg aacgatatcc gtatccgcca tgatttcttg gctcaagtca
    40861 tgctccatct gataagccat aatatctctg agtccaatcg tcccaacaaa ctgtttttca
    40921 tctgtcacaa cgggaacacg ggtataggtc atctgactga gcaagagggt cgcatgatcc
    40981 gcattgtggg tatcaatcaa cacagctaga tttttagcag gggtcaaaaa agtttcctcc
    41041 tgccccaaca agaaagtctc aaactccttg gcaatcatcg gctaaactcc ttggacaaac
    41101 ctggatacac ctcgtgatct cgtgtcaaaa agtccacttt gaagtaacta tcatcaatct
    41161 ccacacgagc atagagacat tctctgatgg tacctcgtgg ttgactgata gaacctggat
    41221 ttagaaagag gatcttgcct tccaaccaag cacttggcac atgcaagtga ccatagaggc
    41281 agatagcggc ctcttcctcc tgagcccagt agtccaactt ttgaaagttg aaattgatgt
    41341 caaacaagtg accatgagtt tggataatct tggtcgaacc aagctcagtc accagacgtt
    41401 ctgggtagcc ggcgtagaag tccatgtttc ctttaacaac gcggatgccc tcccaaagtg
    41461 gagaatccgg acgtagttca gaatcgccgt tatgaaaaac ggcatcgact ttgcccacat
    41521 agcgatcacg gacttcttcc acaatcaagc tatcgccatg ggaatcgctc attacaatga
    41581 tggtttgctt tgccatgatg gaaatacctc caaaagtttc ttaacggcta aggcacggtg
    41641 agattgacta tttttttctt ccagggttaa ttcagctgat gacttacctg tctctcctac
    41701 aaggaagagg ggatcatagc caaagccatt ttcaccctta ggttcaaagt taatataacc
    41761 tgaccagtct gcttcaacaa ctaaactttc cttatttggg ctggctacga ctagggttgt
    41821 gtggaactga gccgagcggt ccttgagttc aaagaccatg gccaattcgt gcaagagttt
    41881 ggcattattt tcacggtcag ttgctcccac acctgcgaaa cgagctgacc agacgcctgg
    41941 taagccacca aggacatcga ctttgagacc agaatcatct gccaaaacca tcttgcccgt
    42001 taattgagaa atggtttctg ccttaaggcg ggcattttct tcaaaggtca tacctgtttc
    42061 tgctacttca ggcaggtcag ggtagtcatt aagattttcc acatcgtagc ctaacttatc
    42121 aaagatagct cggaattcct tggttttgcc ttcgttacga gtcgcaatca acaaggtttc
    42181 tctgaccttg cttgtctcaa agaaatcatg aacattgacc ccttctttag gcaattctac
    42241 atacaagagt tgcccatttt caaccaagag cagggcccca tgacgttgaa taacttccaa
    42301 gtttcgtccc atttcttgat taagcatgtc taccacaaag gagaacaaac ggtaggtaga
    42361 accatagcgt aaaacagtaa ctgaaagcgg gaaaccatac tcttcatctc caaatatttt
    42421 ggagaattca aacagaggaa aatctgtctt atagtcgctc aaactgttaa cgccaccaaa
    42481 aatactataa gacccaacat accaatcctg gtcatcctta tattcataaa ttttatttgt
    42541 cataattcta catgctccac ataaatctct ttttccagcc attcttcacc aatttgtgca
    42601 aaactttggc tactggctgt tgtgtaaaaa cggtgatgga gtggtccagc atcgcgacca
    42661 cgattgattt caaaataatt gagtaagact gagatatccc gtacgcactc tgccccacta
    42721 tcgatgagct gaacctttgg ccccatgaca ttttggataa tagggcgaag gagtggataa
    42781 tgagtacagc ccaaaatcag gctatccacc tttccaacca agggacgcag ggtttcatag
    42841 accaccttct tggtaacact ggttgacagg gcacctgact caaccaaggg agcaaacttg
    42901 ggacaggcca agctctccac ctgtaagtcg ggatccagat catggatttt ctgacggtat
    42961 atgtctgatt gtaccgtcat gggcgttcca atcactccga ttttcccacc ttgactggac
    43021 ttgatggctg ccgaagctcc tggcaaaatt acacccaaga caggaatatc tagttgagcc
    43081 ttgatttctt cccagacgac cgcagtcgca gtgttacaag caatgacaat cattttgaca
    43141 tccttggtca agagaaagtt gaccagctgc caagtatatt cacgaatttg ctcagctgga
    43201 cgggggccat agggcgcccg cgccgaatct ccaatataga cgatttcttc atggggaagc
    43261 tggcgcatga gctcgcgcac aacggtcaag cccccgacac ccgaatccaa aaaaccaatt
    43321 ggtcgattat ccatacagtc ttctttctag tcttttttct gattgatcgt tcattatgat
    43381 tccttgtact gaacgaactg accgacagct tgatagaatg tcaactacct ctctcttaat
    43441 cataatcaaa tatcaataga atgcaaggaa aaagtctcat ccctaaacca taaccaacat
    43501 agtgagaagt ctggaacttt catcccagac ttttccttat ttattttttc tttttattgt
    43561 tagcaagggc tgccttttgt tggcggatga tttggtggta aacttgttgt accttagctt
    43621 cgcttggttt ttgaccattt gcactcaaaa gagtacgaac tgcttcagca ttcaaacgtg
    43681 ggttgtcagc aaattctttt tcgatttgct tacgaaccaa gtacattcct ccaagagctc
    43741 ctcctagaaa agctagcaca atcaatacaa ttgctaaaag taaatccatc atttttctcc
    43801 tgtttctttt tgagtccctt tcattatacc acaaactagc caccctgacc agtttgttct
    43861 acactttcag ggatggaata gacagcaaaa agaaccctgc ttttctgaaa aagaggtctc
    43921 cttgctaagt ttaatttaca taaatagcca gtgtttgata gggttttagt agaattttct
    43981 cagacacttc tgcatcttca tagtttgaaa tcaaaatctg tccattttgg tagactgctg
    44041 gcaagtcgat ttccacttct ttagcataaa agttattgag cactagtaac ttttgatcct
    44101 caaactggcg ttcaaaagcg tagacttgtt tgctatcttc aaaggctggt ttgtaacttc
    44161 cttctgaaat gattggcatt tccttacgca gtcgaatcaa gtcttgatag aaggtaaaaa
    44221 tcggaccctg gatttcattt tctacattga tgtctttata ggatttacca gctttcaacc
    44281 aaggagtgcc tgttgaaaat cctgcatttt ccgaagcatc ccactgcatg ggaatgcgtg
    44341 aattatcacg cgacttagct tgaataatct ggaaggcttc ttgctgactc tttccttctt
    44401 ctaggagcat ctgataggca ttaagcgatt cgacatccac gtaatcagcc atagaatcat
    44461 agtctgggtc aatcatcccg atttcctcac ccatgtagat ataaggtgtc ccacgtgaca
    44521 ggtgaatgct ggctgctagc atggtggctc cttccttgcg gaagttttga atatcgacaa
    44581 aacggttcaa ggcacgtggt tgatcgtgat tgttccaaaa gagggcactc caaccgtctt
    44641 tatcactcat ttccttaccc caactatggt aaagactctt caactcttca aaatcaaagg
    44701 gagccaaggt ccacttttgt ccatccttat agtccacctt gaggtgatga aaattaaagg
    44761 tcatggataa ttcctgacga tcaggcgacg aatagaggac acagttttcc atggtggtag
    44821 aagacatttc cccaactgtc ataaagctat cgtcagatcc aaaagtggct tggttcatca
    44881 tacgcaaata gttatgaacg atgggtttgt ctgtataagc tggcttccct tcattttcag
    44941 gacagtccac tgaaacctcg tccttaccaa tcaaattgat cacatcaaat cgaaaacctt
    45001 tgacaccctt gtcgcgccag aaattaacaa ccttgaaaag ctccttacgg acattgggat
    45061 tgcgccagtt aaggtcagcc tgggtctcat caaataggtg aagatagtat ttcccagtat
    45121 ccccgaaagg cgcccatgca gaaccaccaa acttagactg ccaatctgtt ggttggtctt
    45181 ggatgaagaa aaagtcttga taatacttat caccagctag ggctttctga aaccattcat
    45241 gctctgtcga acaatgatta agtaccatgt ccagcataaa gtcaatcttg tgctctttac
    45301 cgatacacac catttcctca aaatcagcca tatcaccaaa aagaggatcc actgccatat
    45361 aatctgaaat atcgtaacca ttatcccgtt gaggacttgg atagaatgga ttgagccaga
    45421 ccatatccac acctagtttg gctagatagg gaatttttcc gataatccca cggaaatccc
    45481 caataccatt gccagtggtg tctttgtaag attttggata gatttgatag actacttttc
    45541 ctttatcaag tgtcatctgt ttctcctttt ctgataaaag ggaggaagca gtcttccgtc
    45601 cctatttgtg ctatttcaat tatactcaat gaaaatcaaa gagcaaacta ggaagctagc
    45661 cacaggttgc tcaaaacact gttttgaggt tgcagataga gctgacgtgg tttgaagaga
    45721 ttttcgaaga gtattagatt cgtgtagcga ccatgagaga tgctccagct tgaatcgttg
    45781 tcggataagt tccgggaata gtcgctgtat aagcatcttg gttggtgatg ataacaggag
    45841 tttctgtcac cagacctgca gccttaatga catccatatc aaaacgaatc agttgctgac
    45901 caactgtaac gtgatctcct tggactacaa gactttcaaa acctttgcca tcaagaccta
    45961 ctgtatccat accgatgtgg atgagcaatt caactccctc gtcagagaca atgccgatgg
    46021 catgcttggt agggaaaaga accgtcactg tcccattaac tggagaggtc aactcacctt
    46081 ggcttggttc aatgactaga ccttgcccca tgacacctga tgcaaaaata ggatccgtcg
    46141 cttgactcaa ttctttcact tggccagtta gtgggctgat aatttctacc gaagtaagtt
    46201 ctactggttc atggttcaca aattctgctt cttcttgagc aacgaattct gcctgcaagt
    46261 tcgtatcgcc ctctgttttt gtaaagagac cagccttgcg gaagaagaaa gtcaagagca
    46321 ttggaacaac aatcgcaact agcatagttc ctgcaaatgg cagcatgtat tgaggttgaa
    46381 tagagagaat acctggcaaa ccaccgatac caatagaagc cgcagttaca ttaaaagtaa
    46441 cggataacat gcctgcaagg gctgaaccag tcatcccagc aacaaatgga taaatatatt
    46501 ttacgttaac cccaaaaaga gctggttctg taacaccgag ataggctgaa atggttgcag
    46561 gaagtgaaac ctgagcctca cgctcatcat ggcgatgcat gaaataatag gcaaacacgg
    46621 ctgagccttg agcaatatta gaaagagcaa tcattggcca tagggcagtg ccaccagcat
    46681 ccgcaatcaa ttgtgtatca atggcattgg tcatatggtg cagacctgtg atgacaaatg
    46741 gagcgtagag ggcaccaaaa attgcaccga agagccattt aactggacca gttaaacctg
    46801 ccaagacaac tgatgaaagt ccttgtccaa ttgtccaacc gattggtccc aaaacagtat
    46861 gagccaaaat caaggctgga atcaatgaca agaaaggtac aaaaatcata gaaatgactt
    46921 ctgggatatg cttgcgccag aagatttcaa gataagatag actcaaacct gcaagcaagg
    46981 ctgggataac ttgggcttgg taaccgatac gattaacagt aaaatagcca aaattccaaa
    47041 cccagtttgc cgcgatatca gctgctggcg ttgaagcaac cgcataggca ttgagcaact
    47101 gaggcgatac caaacagatt ccgagaacaa ttcccaaaat ttggctggtt cccatcttac
    47161 gagaaacaga ccaagtaatc cctactggta agaactggaa gatagcttca ccaggcaacc
    47221 agaggaaatg attaacacct gcccaaaact gagaggattc tgtgatggtc ttgccatcca
    47281 acatcgacca atggacacct tccaagacat tacggaaacc gaggatcaat cctccgacta
    47341 tcaaggctgg aataatcgga gtaaaaatct ccgccagagt ggtcatgaca cgttggacca
    47401 cgttttgatt actcttagct gcagacttgg ctgcttcttt ggaaacaccc tcaatacctg
    47461 aaacagctgt aaaatcatta taaaagatgg gcacgtcatt tccaatgatt acctgaaatt
    47521 gacctgcatt tgtaaaggtt cctttaacag ctggaattga ctcgatagct ttaacattag
    47581 ccttcttatc atttcctaaa acaaagcgca tccgtgttgc acagtgagtt acggcagtca
    47641 cattttcttt gcctccgatt gcctgaagca gatctttggc ttcttgttca aattttccca
    47701 tttgattctc cttatacttg tcaaagcaag tttgatttga taagtatatt gtaaacgata
    47761 ccaaacttgt ctgcaacttg tttggtataa aaagggtgtt tttttgtaaa ttttctagca
    47821 cttgtatggt aaaatagata caggtgttca ttaaactaga ctaaaaacct atttaagcag
    47881 gcaaaatgaa gaaataccaa caattattta agcaaatcca agaaaccatt caaaacgaga
    47941 cttacgctgt cggagatttc cttcctagcg agcacgacct tatggagcaa tatcaagtga
    48001 gtcgtgatac cgtccgaaag gccctgtctc tcctccaaga ggaaggattg atcaaaaaga
    48061 taagagggca aggttctcaa gtcgtcaaag aagaaaccgt caatttccct gtatccaacc
    48121 taaccagcta ccaagaacta gttaaagaac ttggactgcg ctctaaaacc aacgtggtca
    48181 gtctggacaa gattattatt gataaaaaat cctcactgat aaccggtttc ccagagtttc
    48241 ggatggtttg gaaggtggtc cgccagcgtg tggtggatga tctggtatcc gttctggata
    48301 cggactatct ggatatggaa ctcatcccaa atctcactcg ccaaattgct gagcagtcta
    48361 tctattctta tatagaaaat ggcctcaaac tccttattga ttatgctcag aaggaaatca
    48421 ccattgacca ctcaagcgac cgagacaaga ttctcatgga cattggcaaa gacccttatg
    48481 tcgtttcgat taaatcaaaa gtctatctcc aagacgggcg ccaatttcag tttaccgaaa
    48541 gtcgccataa gttagaaaaa tttagatttg tagattttgc aaaacgcaag aaataaaaga
    48601 ctgagacacc agatctcagc ctttttcttt atcccaaaac taattcatca ctgaccagac
    48661 tttggccact atttttctgg aagagatgca taaggtcttc aactgtcaga tgctttttct
    48721 cttctccctt gacatccacc actatcttgc cttgatagag cataatgaga cgattgccgt
    48781 actcaatcgc atgattcata tcatgggtaa tcatcaaagt cgtccactga tggtactcca
    48841 caatcttttg cgtcaagtcc atcaccattt gactggtttt cgggtcaagt gccgcagtat
    48901 gttcatccaa aagcaaaagt ttgagtttca ccagagctgc catgactagg gtcaaagcct
    48961 gtctttgtcc tcctgagaga tattgagtat ctacttttaa gcggttttca agaccaatat
    49021 tcaactcctt caaggcctct tggaactgga ttctatcctt ctccttcacg ccccaaccaa
    49081 gccctctctt ttgcccacgt ctcaaggcaa tagccatatt ctcctcaatc gtcaaacgag
    49141 aagctgttcc catcttagga tcttgaaaaa cacgggcaat atccttggct ctctttctga
    49201 cactcagatg tttaatggat ttccctgcca gtagaaggtc cccttcgtcc accgatagat
    49261 taccagccaa gatattcatc aaagtggatt ttcctgctcc atttccacca atcacagaga
    49321 taaaatctcc ctcttcaacc tctaaatcta atcctttgag gacatggttc tcattgaccg
    49381 tccctgcttc aaatgtcttg tgaatatttt caagtgttaa caaacttgcc ataactttct
    49441 cctcctattc atttctcaat ttcagaccac gaatctttaa tctcttttgc aatgctggtg
    49501 caaataaaac caaagcgagc aagattgcat taaagagacg taccaagttt tgatctagat
    49561 ttggaatttc atagatattt aaaataatca aacggtaaac aatagcaccg attccgatgg
    49621 ataataagcg gcctccaatg gtcaagtcgt gtatcaagac ttccgagctc aaaccaacaa
    49681 caatggttcc tgtcccagaa gtcacatctg aaaatccatc attttgggca aacaaggaac
    49741 cacatagggc aatcaaaccg gttgaaatca tgtaaccaac aatcttcatg gtgtttacat
    49801 tgactccatt ggcctcactc atcgggatat tgtccccagt cgaacgcaag accaaaccaa
    49861 tctctgtttt catcaaaagg gtcaaaacca aacaagtaag agacagacta aactaagtga
    49921 gaaaacagct ccttcatttg tcagacccaa gctcgccaac tgtttaaaga cggttgcaga
    49981 atctcccaag gaaagattgg gtacactgcc catgatttta atattgattg aatagagccc
    50041 tgtcaaggtc acaatccctg tcaagagagc tgggattttc atcttggtgt ggagcattcc
    50101 tgatataaga cctgctacca tacctgccag caaagcaagt aaagtcgcaa gccaaggatt
    50161 tgcccctgcc tgtatctgtg atacaacgat tgctgccccc ataggaaagg ctccctcagc
    50221 agtcatatcc gcaatatcca aaatacggaa agtcaagtag accccaattg ccataatcga
    50281 ccacaacaaa ccttctgata aactagataa cacaaaattc atcttaatcc tccttattcc
    50341 ttgccttcta acttactaat atcaattcac aatgcatctg ccatttcttg attagtatgc
    50401 aattccagtt tttcaggcaa ctcaactgct atattttctg gttcctcacc ttttaaaaca
    50461 cgaatcagca tgcgagctgt ctgtcttccc aattcttcat aattggttcc gtagttatac
    50521 aagccaccaa cagcaatcat ttctgttgaa ccaccgaata ctggaacctt gtgtttaata
    50581 gaaacctgct taactgtttc catggttgac gaaatgatat tatcagttgg gacaaaaacc
    50641 atatccacct ctgccatcaa actctctgct gccgccttga cgttattact gtccaagatt
    50701 gttttttcaa caacggtaaa gcctttttct ttcagaaatc gcttagcttc atccttttaa
    50761 acaaccgaat tgggctcgct ctgagtatag aggattccaa tcgttttagc ctttagcaac
    50821 actttcttta tcaaattgat ttgggttgaa atggcatctg atgactgatc gcttgtccca
    50881 gttacattgc ccccaggatg ttctcttgac tcaaccaact tggcactgac tgggtctgtt
    50941 acagctgaaa agataactgg tgtcgtttgc gtcgtattgg ccaagctctg agcagaaggc
    51001 cttgcgatgg ctagaacgac atcgctggat tctgctagtt gctgggaaat cgtttttaga
    51061 tttctttgtt ctccctgtgc attttgcaaa tcaatctcaa tattttcccc ctcaacatag
    51121 ccttgtttgg ccagctcatc cacaaatcct tctctagtag cgtctaagga ctggtgggta
    51181 ataaactgcg aaataccgat acgaaagaca tctcttttct tatctgcctt caactgatgc
    51241 aaactgatca gagaagtcaa gaggatcccc actaccaaga gggggctagt gattttcgaa
    51301 caactttcat aatgaaactc cttctcagaa aagataaaac aaaaaaacgc ctagatacta
    51361 tctaaacggg tacttgaaat aacctaacaa gttacaactt agctggtcca tttagatatt
    51421 catctatatg gaccacaatc aaaaatctta gccacataga tacaaacaaa ttgcttgaac
    51481 tgtttgcatc catggtgaca tgtctacaaa cactatctaa agtagctaaa gtaaaagttt
    51541 tgattcatag ttacggcttg tctcttattc atttcttttt ctgctttctt ttttgatcct
    51601 tcctatccta ccaccttttt catcacctgt caataatatt tcaaaatttt ttaaaatttt
    51661 tcgaaaattc tttcag
//
LOCUS       DAVAZT010000005        50102 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVAZT010000005 DAVAZT010000000
VERSION     DAVAZT010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50102)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50102)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50102
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.005"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..746
                     /locus_tag="VQT45_000262"
     CDS             <1..746
                     /locus_tag="VQT45_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET2358660.1"
                     /translation="YELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTD
                     KKFVFIIDEINRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVY
                     IIGTMNDIDRSVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAA
                     IENVQELNSHYHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLK
                     KAFELTNNEQKDQAVADDNESDENDDADY"
     gene            733..2085
                     /locus_tag="VQT45_000263"
     CDS             733..2085
                     /locus_tag="VQT45_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HET2358661.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKKQKILETINQEIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYTTREFTYDNPLIQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLVFPSKDKVIDNEMGNL
                     AGYGALLKKWSIQIPQKSSSYSAFCKMMENSDYSAFCKMMENSEENFKAIIDEEVGRK
                     "
     gene            2260..3246
                     /locus_tag="VQT45_000264"
     CDS             2260..3246
                     /locus_tag="VQT45_000264"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HET2358662.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKQMHDQGLIASISVGVKDYEY
                     DFVSQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            3310..3381
                     /locus_tag="VQT45_000265"
     tRNA            3310..3381
                     /locus_tag="VQT45_000265"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3343..3345,aa:Arg,seq:ccg)
     gene            3564..4262
                     /locus_tag="VQT45_000266"
     CDS             3564..4262
                     /locus_tag="VQT45_000266"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HET2358663.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            4253..7792
                     /gene="smc"
                     /locus_tag="VQT45_000267"
     CDS             4253..7792
                     /gene="smc"
                     /locus_tag="VQT45_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HET2358664.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKSEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAITVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDAVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLRSEEAALKTLQDQMATLTERLEVIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQDRLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDFEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEEAKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRYLQSQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNIEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKDRFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            7789..8583
                     /locus_tag="VQT45_000268"
     CDS             7789..8583
                     /locus_tag="VQT45_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2358665.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGETWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKDQSVIAYMEGL"
     gene            8583..9401
                     /locus_tag="VQT45_000269"
     CDS             8583..9401
                     /locus_tag="VQT45_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2358666.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKATLKAASDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGHEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            9405..10625
                     /gene="ftsY"
                     /locus_tag="VQT45_000270"
     CDS             9405..10625
                     /gene="ftsY"
                     /locus_tag="VQT45_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HET2358667.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAVLEESQDSEPAVGVSQEEIEELPEEEKLEHEGTIEENNSEVLEAERPQTEETVQ
                     EKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEELLIMSDVGVQVASNLTEELR
                     YEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQDNLTVMLFVGVNGVGKTTS
                     IGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWGRRVDVPVVTGPEKADPASVVFDG
                     MERAVAEGIDILMIDTAGRLQNKDNLMTELEKIGRIIKRVVPEAPHETFLALDASTGQ
                     NALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREELNIPVKLIGFGEKIDDIGEF
                     NSENFMKGLLEGLI"
     gene            complement(10671..12158)
                     /locus_tag="VQT45_000271"
     CDS             complement(10671..12158)
                     /locus_tag="VQT45_000271"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HET2358668.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYQSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPAIFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRSVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRFE"
     gene            complement(12307..13047)
                     /locus_tag="VQT45_000272"
     CDS             complement(12307..13047)
                     /locus_tag="VQT45_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2358669.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDNLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(13047..15212)
                     /locus_tag="VQT45_000273"
     CDS             complement(13047..15212)
                     /locus_tag="VQT45_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET2358670.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            15385..16338
                     /locus_tag="VQT45_000274"
     CDS             15385..16338
                     /locus_tag="VQT45_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2358671.1"
                     /translation="MKNKRIFKDFQASKMNLNLYTSPLLAFVFVFIGEFVAYTLYGIS
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENCLSNLLKGFSLGLALFLLTLLSLVVLGQYRLESIHLNPYYLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            16415..18403
                     /gene="uvrB"
                     /locus_tag="VQT45_000275"
     CDS             16415..18403
                     /gene="uvrB"
                     /locus_tag="VQT45_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HET2358672.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            18413..18976
                     /locus_tag="VQT45_000276"
     CDS             18413..18976
                     /locus_tag="VQT45_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2358673.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKTNDGYYQINGNS"
     gene            18942..19430
                     /locus_tag="VQT45_000277"
     CDS             18942..19430
                     /locus_tag="VQT45_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2358674.1"
                     /translation="MTVIIKSMETPEEIEGKPLVHWQTWREAYDGLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAMDGMKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LIKAALIALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDEQEKILELGKPIKEKRMVFY
                     SK"
     gene            19503..19970
                     /locus_tag="VQT45_000278"
     CDS             19503..19970
                     /locus_tag="VQT45_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET2358675.1"
                     /translation="MSRAQLTILTNICLIEDLEAQRVVMQYRAPETNRWSGYAFPGGH
                     VENGESFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVVCYKATEFSGTLRS
                     SDEGEVSWVQKDQIPNLDLAYDMLPLMEMMEASDKSEFFYPRRTEDDWEKKIF"
     gene            complement(19967..20482)
                     /locus_tag="VQT45_000279"
     CDS             complement(19967..20482)
                     /locus_tag="VQT45_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HET2358676.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFKPLSELTDGVHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(20494..21021)
                     /locus_tag="VQT45_000280"
     CDS             complement(20494..21021)
                     /locus_tag="VQT45_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2358677.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGSLYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(21299..21862)
                     /locus_tag="VQT45_000281"
     CDS             complement(21299..21862)
                     /locus_tag="VQT45_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2358678.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(21846..22397)
                     /gene="coaC"
                     /locus_tag="VQT45_000282"
     CDS             complement(21846..22397)
                     /gene="coaC"
                     /locus_tag="VQT45_000282"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HET2358679.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(22409..23098)
                     /gene="coaB"
                     /locus_tag="VQT45_000283"
     CDS             complement(22409..23098)
                     /gene="coaB"
                     /locus_tag="VQT45_000283"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HET2358680.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            23328..24998
                     /locus_tag="VQT45_000284"
     CDS             23328..24998
                     /locus_tag="VQT45_000284"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HET2358681.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELEIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNALSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            25326..26501
                     /gene="mutY"
                     /locus_tag="VQT45_000285"
     CDS             25326..26501
                     /gene="mutY"
                     /locus_tag="VQT45_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HET2358682.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     LIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            26556..27260
                     /locus_tag="VQT45_000286"
     CDS             26556..27260
                     /locus_tag="VQT45_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2358683.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            27253..28602
                     /gene="vicK"
                     /locus_tag="VQT45_000287"
     CDS             27253..28602
                     /gene="vicK"
                     /locus_tag="VQT45_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HET2358684.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            28604..29413
                     /locus_tag="VQT45_000288"
     CDS             28604..29413
                     /locus_tag="VQT45_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET2358685.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            29504..29746
                     /locus_tag="VQT45_000289"
     CDS             29504..29746
                     /locus_tag="VQT45_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HET2358686.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            29748..30002
                     /locus_tag="VQT45_000290"
     CDS             29748..30002
                     /locus_tag="VQT45_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HET2358687.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            30049..30822
                     /locus_tag="VQT45_000291"
     CDS             30049..30822
                     /locus_tag="VQT45_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HET2358688.1"
                     /translation="MKKKWFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFTTKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLAKLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPASIFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLKDELSSQRILLEKQSKKIEELHKMIQDLIEKT"
     gene            complement(31082..32068)
                     /locus_tag="VQT45_000292"
     CDS             complement(31082..32068)
                     /locus_tag="VQT45_000292"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HET2358689.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGLYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            32262..34730
                     /gene="gyrA"
                     /locus_tag="VQT45_000293"
     CDS             32262..34730
                     /gene="gyrA"
                     /locus_tag="VQT45_000293"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003244540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HET2358690.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIALRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEE"
     gene            34730..35473
                     /gene="srtA"
                     /locus_tag="VQT45_000294"
     CDS             34730..35473
                     /gene="srtA"
                     /locus_tag="VQT45_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HET2358691.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
     gene            35717..36514
                     /locus_tag="VQT45_000295"
     CDS             35717..36514
                     /locus_tag="VQT45_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HET2358692.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            36662..36784
                     /locus_tag="VQT45_000296"
     CDS             36662..36784
                     /locus_tag="VQT45_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HET2358693.1"
                     /translation="MTCDFKFETLQLHAGQVVAPATKSRAVPIYQTTSFIFDDT"
     gene            36806..37846
                     /locus_tag="VQT45_000297"
     CDS             36806..37846
                     /locus_tag="VQT45_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HET2358694.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILALAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFVDVDNLEEVEAAIKDNTKLVLIETLG
                     NSLINIPDLEKLAEIAHKHQIPLVSDNTFAIPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGIIVDSGRFDWTASGKFPQFVDEGPSCHNLSYTCDVGAAAFIIAVRVQLLRDTGA
                     ALSPFNAFLLLQRLETSSLRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYHALA
                     EKYLPKDVGSIFTFHVKGGEEEARKVIDNLEIFSDLANAADAKSLVVHPATTTHGQLS
                     EKDLEAAGVTPN"
     gene            38017..39291
                     /locus_tag="VQT45_000298"
     CDS             38017..39291
                     /locus_tag="VQT45_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HET2358695.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKDFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            39301..40179
                     /gene="truB"
                     /locus_tag="VQT45_000299"
     CDS             39301..40179
                     /gene="truB"
                     /locus_tag="VQT45_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HET2358696.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEIILGYSTTTEDASGEVVAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALTLEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            40447..40722
                     /locus_tag="VQT45_000300"
     CDS             40447..40722
                     /locus_tag="VQT45_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET2358697.1"
                     /translation="MEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQSVMANLSQGL
                     SLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            40830..41468
                     /gene="udk"
                     /locus_tag="VQT45_000301"
     CDS             40830..41468
                     /gene="udk"
                     /locus_tag="VQT45_000301"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HET2358698.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            41596..42936
                     /locus_tag="VQT45_000302"
     CDS             41596..42936
                     /locus_tag="VQT45_000302"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HET2358699.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            42914..43126
                     /locus_tag="VQT45_000303"
     CDS             42914..43126
                     /locus_tag="VQT45_000303"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HET2358700.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            43123..43998
                     /locus_tag="VQT45_000304"
     CDS             43123..43998
                     /locus_tag="VQT45_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HET2358701.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLESLQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            43991..44806
                     /locus_tag="VQT45_000305"
     CDS             43991..44806
                     /locus_tag="VQT45_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HET2358702.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHSVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            44799..45230
                     /locus_tag="VQT45_000306"
     CDS             44799..45230
                     /locus_tag="VQT45_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET2358703.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            45237..46904
                     /gene="recN"
                     /locus_tag="VQT45_000307"
     CDS             45237..46904
                     /gene="recN"
                     /locus_tag="VQT45_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HET2358704.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRTIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLDLNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNKMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            46906..47634
                     /locus_tag="VQT45_000308"
     CDS             46906..47634
                     /locus_tag="VQT45_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HET2358705.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQPQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYSRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            47713..49536
                     /gene="lepA"
                     /locus_tag="VQT45_000309"
     CDS             47713..49536
                     /gene="lepA"
                     /locus_tag="VQT45_000309"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HET2358706.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(49738..49818)
                     /locus_tag="VQT45_000310"
                     /pseudo
     CDS             complement(49738..49818)
                     /locus_tag="VQT45_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
BASE COUNT        15243 a         8948 c        11369 g        14542 t
ORIGIN      
        1 tttacgagtt gtataaagat aaaaattata ataagcaaga atactacaaa agtggtggaa
       61 aaactgtcct agaaacattg agaaagagat ttggtttgaa agactatgtt tccccaacag
      121 aaattgatac tgataagaaa ttcgttttca tcatcgatga aatcaatcgt ggggagattt
      181 ctaagatttt tggcgaactc tttttctcta tcgaccctgg ctatcgtggt gaaaaaggaa
      241 gtgtttctac ccaatatgca aatctacacg aaactgatga aaagttctat atccccgaaa
      301 atgtttacat catcggaact atgaatgata ttgatcgttc agtggatacc tttgattttg
      361 ctatgcgtcg tcgttttcgt tttgttgaag ttactgccga gggtcaagtt ggcatgttgg
      421 ataaagagct gaatatccat gcagaagaag caaaaattcg tctaagaaac ttgaacgctg
      481 ctatcgaaaa tgttcaggaa ttaaacagtc attatcatat tggaccaagt tattttctta
      541 agttgaagga tgtagatttt gactatgaat tactctggtc cgattatatt aagcctctcc
      601 tagaagacta cttgcgaggt tcttatgatg aggttgaaac tttggaaact ttgaaaaaag
      661 catttgaact gacaaataat gagcaaaaag atcaggcagt agctgatgac aatgaaagcg
      721 atgaaaacga tgatgcggat tactgataat caacacaaga ttattaaaga aaaatttgtt
      781 gaagaatatc ctaaactaag caatcttctt ttagacagaa ccttggaaag tctatcccaa
      841 gatgaacgta ttttcatttt tccaaatgat ttgactcata ctccagattt ggataaaaaa
      901 caaaagattt tggaaacgat caatcaggaa atcaagacag gaaatgtgat tggttttctt
      961 ggatatggtc aggaaagatt aacgatttcc tcacgatttt ctgatgagag taatgaccat
     1021 tttttgcatt atctcttaaa caaggttctt catatcaatc tcactagttt agatgttgct
     1081 ttgtctcgtg aagagaggct ttatcaactt ttgatgtatc tcttccccaa gtatctacaa
     1141 gctgctattc gaaaaggtct ttataaggaa tatcatcgat tttctcataa cgacagtcat
     1201 gttaagggag tgattgatgt aagaaaccat ctcaagaaaa atcttccttt cacgggaaat
     1261 attgcctaca caacgagaga gttcacctat gataatcccc tcatacagtt ggtccgtcac
     1321 actattgaat acattaagaa tcagaaaagc attggtcaag gggtactaga taatctctca
     1381 actagtcgtg aaaacgtatc tgaaatcgtg cgtgtaacgc cctcttataa actagctgat
     1441 cgtgctaaga ttattcgggg aaatcaatct aaacctatac gtcatgcata ctttcacgag
     1501 tacagaaact tacaagaact ttgtctgatg atcctaaacc aagaaaagca cggtttaggg
     1561 tatcaagatc aaaaaatcta tggtattctc tttgatgttg cctggctttg ggaagagtat
     1621 gtttacacct tgttgccaaa aggttttgta catcccagaa ataaggataa gacggatgga
     1681 atttcagtat tttctgttgg gaaacgaaaa gtatatccag atttttatga cagagaacga
     1741 aagattgttc tagatgcaaa atataaaaaa ctggaattga ctgaaaaagg aatcaatcgt
     1801 gaggacttat tccagctgat ttcctattct tatattttaa aagctgagaa ggctggactt
     1861 gtttttccga gcaaggacaa ggttattgat aatgagatgg gaaacctagc aggttatgga
     1921 gctttgttga agaaatggtc tatccaaatt cctcagaagt cttcatctta tagtgcattt
     1981 tgtaaaatga tggaaaattc agattatagt gcattttgta aaatgatgga aaattcagaa
     2041 gaaaatttta aagcgattat tgatgaagaa gtggggagaa aataatttcc cctctttctt
     2101 ttatttttaa cacaagtaaa acccgaacaa tatatttcaa ttcataaaat aatttgacaa
     2161 aaactgtact ttggtttata ataaattaag gaaacgtcgg aaaagacgta gtgatgcgag
     2221 agcataggta ggtcattaca aaagaaacga gacatcgata tgttaaatga atttccaatt
     2281 tttgattacg aagatattca attgattcca aataaatgtg tcattaaaag ccgtgcagaa
     2341 gcggatacaa gtgtcacttt aggaaatcac acctttaaac tacctgttgt gccagcgaat
     2401 atgcagacga ttttggatga aaatgtagca gagcaactgg ctaaaggtgg ttacttctac
     2461 attatgcacc gttttgatga ggcaggacgc attcctttta ttaaacaaat gcacgatcaa
     2521 gggctcattg cttccatctc tgtcggtgtt aaggactatg agtatgattt tgttagccag
     2581 ctcaagactg atgctcctga gtatatcact attgatattg ctcatggtca tgcggatagc
     2641 gtgatttcta tgattcaaca tatcaagaaa gaattgccag atacctttgt cattgctgga
     2701 aatgtgggaa caccagaagc tgtgcgtgaa ttggaaaatg ctggtgcgga tgctactaag
     2761 gtcggaatcg gtcccggtaa ggtttgtatc accaaggtta agactggttt tggtacaggt
     2821 ggttggcagt tggctgctct acgctggtgt gccaaggctg cgcgtaaacc gattatcgct
     2881 gatggaggaa ttcgtactca cggtgatatt gctaagtcta tccgcttcgg tgctagcatg
     2941 atcatgattg gttccctctt tgcaggacac attgaaagtc cagggaaaac gattgaagtc
     3001 gatggtgaac agttcaaaga atattatggt tcagcctcac aatatcaaaa aggtgcttac
     3061 aaaaatgtgg aaggcaaacg tatcttgctt cctgctaaag gtcatctgca agacacttta
     3121 actgagatgg aacaagacct tcaaagtgct atttcttatg caggtggacg tcaggttgct
     3181 gaccttaaac acgttgatta tgtgatcgtg aaaaactcca tctggaatgg ggatgcttcc
     3241 cactaagacg gggtctttga ccaaaaaact tgttattaga gcaaatttct gttataataa
     3301 aacaagtttc cacccttagt gtaatggata tcacgtaaga ttccggttct tgagatgggg
     3361 gttcgattcc ctcagggtgg atgtaaacat cctaaaaagc ctttaatagg gcttttttct
     3421 ttatcctgac ccaaatttgc cgctaaaact gagaatctct gtctaaagaa ttcccaaatg
     3481 ctttccagtc ccgttttaga gtgactcagg gggctttttt tgatataata aaaaggactg
     3541 ttatcagtta gaaagaggtt ggtatgaaag aattacaaac tgtactaaag aatcattttg
     3601 caatcgaatt tgcagacaaa aatttactgg aaactgcctt tactcatacg agttatgcca
     3661 atgagcaccg cctcttaaaa atttcacaca atgaacgctt ggaattttta ggagacgctg
     3721 ttctacagtt attgatttca gaatatctat ataaaaaata tcctaaaaag cctgaaggtg
     3781 acctatcaaa actccgtgct atgattgtcc gtgaggagag tttagctggt tttgcgcgtg
     3841 attgccagtt tgaccagttt atcaagttgg gtaaagggga agaaaaatca ggtggtcgca
     3901 atcgtgacac cattcttggt gatgcctttg aagcctttct tggtgccctt cttttggata
     3961 aggatgtggc caaggtcaag gaatttatct atcaagtcat gattcctaag gttgaagcag
     4021 gcgaatttga gatgattaca gactataaaa cccatctcca agagttactt caggtcaatg
     4081 gtgatgtggc tattcgttat caggtgattt ctgaaacagg gcctgctcac gataaggtct
     4141 ttgatgtaga agttcttgtt gaaggtaaga gcatcggtca aggccaaggt cgttctaaga
     4201 aattagcaga gcaggaagct gccaaaaatg ccgttgagaa ggggctggat tcatgtattt
     4261 aaaggaaatc gaaattcagg ggttcaagtc ttttgctgat aagaccaagg tcgtttttga
     4321 ccaaggtgtg acggcagttg ttggacccaa tggatctgga aagtccaata ttacagaaag
     4381 tctgcgttgg gctttggggg agtctagtgt caagagtctc cgtgggggca agatgccgga
     4441 tgtcatcttt gctggaacag aaagtcgcaa accgctcaat tatgcttctg tagttgtgac
     4501 tctggataat catgacggat ttatcaagga tgcaggtcaa gaaatcaggg tggaacgcca
     4561 tatctatcgt agtggagata gcgaatacaa gattgacggc aagaaagtcc gtctgcgtga
     4621 tattcatgac cttttcttgg atacaggttt gggacgagat tccttctcta ttatttccca
     4681 agggaaggtt gaggagattt ttaattccaa gtctgaggaa cgacgagcta tttttgaaga
     4741 agctgctgga gttttaaaat acaagactcg cagaaaagaa accgagagta aactgcagca
     4801 aactcaggat aatctggacc gcttagagga cattatctac gagttggata atcaaatcaa
     4861 gcctcttgag aagcaagctg agaatgcccg taaatttcta gacttagaag gtcaacgcaa
     4921 ggctatttac ttggatgtat tggttgctca aatcaaggaa aataaggcag aactagagtc
     4981 gacagaagaa gagttggctc aggttcaaga actcttgatg agttattacc aaaagcgtga
     5041 aaaattagaa gaagaaaatc aaactcttaa aaagcaacgc caagatttac aggctgaaat
     5101 ggccaaagac caaggcagtt tgatggactt gactagtctg attagtgatt tagaaagaaa
     5161 attagcccta tcgaaactgg agtctgagca agtggccttg aatcaacagg aggcacaagc
     5221 tcgtttggct gctttggagg ataagagaaa ttcactcagc aaagaaaagt ctgataaaga
     5281 aagctcttta gctctgttag agggaaatct agtccaaaat aatcaaaaac tcaatcgttt
     5341 agaagctgaa ttgctggctt tctcagacga tcctgatcag atgattgagc tcttacgtga
     5401 acgctttgta gctcttttac aagaagaagc ggatgtctca aaccagttga cccgtattga
     5461 gaatgagttg gaaaatagtc gtcagctttc tcaaaaacaa gcagatcaac tagaaaagct
     5521 gaaagagcaa ttagctatag ctaaagagaa ggctagtcag caaaaggaag agcttgaaac
     5581 tgccaaggag caggttcaga aattattggc tgactaccaa gctattgcca aggagcaaga
     5641 ggagcagaaa acttcctatc aagctcaaca aagccaactc tttgaccgtc tggataatct
     5701 caaaaacaag caggccagag ctcaaagttt ggaaaatatc ctgagaaatc atagtaactt
     5761 ttatgcaggt gttaagagtg ttctccaaga aaaagatcgc ctaggtggga ttattggtgc
     5821 agtcagtgag catctgacct ttgatatgca ttatcaaact gccctagaaa ttgcgcttgg
     5881 agcgagtagc caacatatca tcgtagaaga tgaagagtcg gcaaccaagg ctattgactt
     5941 ccttaaacgg aacagagccg gtcgtgcaac ctttcttcct ttgaccacta tcaaggcgcg
     6001 tacgatttct agtcagaacc aagatgctat cactgtaagc ccaggtttcc ttgggatggc
     6061 agatgagttg gtgacttttg atactagact ggaagccatt ttcaagaact tgctagctac
     6121 gacggctatc tttgatgccg tagaacatgc gcgtgcagca gctcgccaag ttcgttatca
     6181 ggttcgtatg gtgacattgg atgggacaga attacgcacg ggtggttcct atgcgggtgg
     6241 tgccaatcgc caaaataaca gtattttcat caagccagaa ctggagcaat tacaaaaaga
     6301 aattgctgca gatgaagcaa gcttgcgttc agaagaagcg gctttgaaga ccttacaaga
     6361 ccagatggct acattgacag aaagattaga agtcatcaaa tctcaaggag aacaggcacg
     6421 tattcaggag caaggcttgt ccctcgctta tcagcaaact agtcagcaag ttgaagaact
     6481 ggaaactctt tggaaactcc aagaagagga aatagatcgt ctttccgagg gagattggca
     6541 agcggataag gaaaaatgcc aagatcgtct tgctgcaatc gccagtgaca agcaaaatct
     6601 ggaagctgag attgaagaga ttaagtctaa caaaaatgcc atccaagaac gctatcaaaa
     6661 cttgcaggaa gagctagcgc aagctcgttt gcttaagaca gaactgcaag ggcaaaaacg
     6721 ttatgaagtt gctgatattg aacgcttagg caaggaattg gacaatcttg attttgaaca
     6781 agaggaaatc cagcgccttc ttcaagaaaa ggttgataat cttgagaagg ttgatacaga
     6841 attgctcagt caacaggcgg aagaagccaa aactcagaaa acaaatctcc aacaaggttt
     6901 gattcgcaag cagtttgagt tggatgatat tgaaggtcaa ctggatgata ttgctagtca
     6961 tttggatcag gctcgccaac agaatgaaga gtggattcgc aagcaaacac gtgctgaagc
     7021 caagaaagaa aaggtcagcg agcgcttgcg ctatttacaa agtcaattaa cagaccaata
     7081 tcagattagc tatactgaag ctctagaaaa ggcgcatgaa ttggaaaacc tcaatctggc
     7141 agagcaagag gtgcaggatt tagagaaagc tattcgctca ctggggcctg tcaatataga
     7201 agctattgac cagtacgaag aagttcacaa tcgtctggat ttcctaaata gccaacgaga
     7261 tgatattttg tcagcgaaaa atctgctcct tgagaccatt acagagatga atgatgaggt
     7321 caaagatcgc tttaaatcaa cctttgaggc cattcgtgaa tcctttaaag tgaccttcaa
     7381 acagatgttt ggaggaggtc aggcagactt aatcttgact gagggagact tgttgacagc
     7441 tggggttgag atttctgttc aacctccagg taagaaaatc cagtcgctta acctcatgag
     7501 tggtggtgaa aaagccttat cagctcttgc tttgcttttt tctatcattc gagttaagac
     7561 tatcccattt gtcatcttgg atgaggtaga ggccgcgctg gacgaagcca atgttaaacg
     7621 ttttggggat tacctcaatc gatttgacaa ggacagccag tttatcgtcg taacccaccg
     7681 taagggaacc atggcagcgg ctgattctat ctatggagtg accatgcaag aatcgggggt
     7741 ctcaaaaatt gtttcggtta agttaaaaga tttagaaagt attgaaggat gacaattaaa
     7801 ctagtagcaa cggatatgga cggaaccttc ctagatggga atggacgctt tgatatggat
     7861 cgtctcaagt ctctcttggc ttcctacaag gaaaaaggga tttactttgc ggtggcttcg
     7921 ggtcggggat ttctgtctct ggaaaaatta tttgctggtg ttcgtgatga cattattttc
     7981 atcgcggaaa atggcagttt ggtagagtat caaggtcagg acttgtatga agcgactatg
     8041 tctcgtgact tttatctggc aacttttgaa aagctgaaaa cgtcacctta tgtagatatc
     8101 aataaactgc tcttgacggg taagaagggt tcatatgttc tagatacggt tgatgagacc
     8161 tatttgaaag tgagtcagca ttataatgaa aatatccaaa aagtagcgag tttggaagat
     8221 atcacagatg acattttcaa atttacaacc aacttcacag aagaaacgct ggaagctgga
     8281 gaaacttggg taaacgataa tgtccctggt gtcaaggcta tgacaactgg ctttgaatct
     8341 attgatattg ttctggacta tgtcgataag ggagtggcta ttgttgaatt agctaaaaaa
     8401 cttggtatca caatggatca ggtcatggct tttggagaca atcttaatga cttacatatg
     8461 atgcaggttg tgggacatcc tgtagctcct gaaaatgcac gacctgaaat tttagaatta
     8521 gcaaagactg tgattggtca ccataaggac cagtcggtta tagcttatat ggagggctta
     8581 taatggcaga tataaaatta atcgcattgg acttggatgg taccttgctg actactgata
     8641 aaaggctgac ggatcgcacc aaggcaactt tgaaagctgc gagtgatcgt ggtatcaagg
     8701 tcgtattgac aactggtcgt cccttaaaag ccatggactt ctttctccat gagttaggga
     8761 ctgacggcca tgaagatgag tataccatta cttttaatgg tggattagtt cagaaaaata
     8821 caggagaaat ccttgataaa acagtctttt catatgatga tgtggcacgt ttgtatgagg
     8881 aaacagagaa attatcactg cctcttgatg ccatctcaga aggaacagtt tatcaaatcc
     8941 aatcggacca agaaagtctt tatgccaaat tcaatccagc tttgactttt gttccagttg
     9001 actttgaaga cctgtctagt caaatgacct acaacaaatg cgtgactgcc tttgctcaag
     9061 aacccttgga tgcagccatt cagaagattt ctccagaatt gtttgaccaa tatgaaatct
     9121 ttaaatcacg tgaaatgttg ctagaatggt caccaaagaa tgttcataaa gcaacaggtt
     9181 tggcaaaact aattagccat cttggaattg atcaaagtca agtgatggcc tgtggtgacg
     9241 aggccaatga cctctctatg attgaatggg cagggctcgg tgttgccatg caaaacgctg
     9301 ttcctgaagt aaaggcagcc gcaaatgtag tgacgccgat gaccaacgat gaggaagctg
     9361 tcgcctgggc tatcgaagaa tatgtgctaa aggagaacta agatatggga ttatttgacc
     9421 gtctattcgg aaaaaaagaa gaacctaaaa tcgaagaagt tgtaaaagaa gctctggaaa
     9481 atcttgattt gtctgaagat gttgatccta ccttcacaga agttgaagaa gtttctcaag
     9541 aagaagctgt gcttgaagaa agtcaggatt cagagccagc tgtaggggtt tctcaagaag
     9601 aaatagaaga attaccagag gaagagaagc ttgagcacga aggaactata gaagaaaata
     9661 attctgaagt tcttgaagca gaaaggcctc aaacagaaga aactgttcag gaaaaatatg
     9721 accgcagtct taagaaaact cgcacaggtt tcggtgcccg cttgaatgcc ttctttgcta
     9781 acttccgctc tgttgacgaa gaatttttcg aggaactgga agaactgttg attatgagtg
     9841 atgttggtgt ccaagtcgct tctaacttaa cggaggaact acgttacgaa gccaagcttg
     9901 aaaatgccaa gaaacctgat gcacttcgtc gtgtcatcat tgagaaattg gttgagcttt
     9961 atgaaaagga tggtagctac gatgaaagca tccacttcca agataacttg acagttatgc
    10021 tctttgttgg tgtgaatggt gttgggaaaa caacttctat cggaaaacta gcccaccgct
    10081 acaaacgagc tggtaagaag gtcatgctgg ttgcagcaga taccttccgt gcgggtgcag
    10141 tagctcagct agctgaatgg ggccgacgag tagatgttcc agtagtaact ggacctgaaa
    10201 aagctgatcc agccagcgtg gtctttgatg gtatggaacg tgccgtggct gaaggtatcg
    10261 atattctcat gattgatact gctggtcgtc tgcaaaataa ggataacctt atgactgagt
    10321 tggaaaagat tggtcgtatt atcaaacgtg ttgtgccaga agcaccacat gaaaccttct
    10381 tggcacttga tgcatcaaca ggtcaaaatg ccctagtaca ggccaaagaa ttttcgaaaa
    10441 tcacaccttt aacgggaatt gttttgacta agattgatgg aactgctcga ggaggtgtgg
    10501 ttctagccat tcgtgaagaa ctcaatattc ctgtaaaatt gattggtttt ggtgaaaaaa
    10561 tcgatgatat tggagagttt aactcagaaa acttcatgaa aggtctcttg gaaggtttaa
    10621 tctaatcaga agcaaaaatc ctgcaaggca taaacttgca ggaaattttt ttattcgaaa
    10681 cgaccatctt gacgataggc gatatctggt tgccaagtcc atttggcacc gaatttttca
    10741 agtaggtcaa agctggcttg aggtcccatg cttccagctt tatagtcatg aagtggggca
    10801 ccattttcag cccagagctc ttcaatacgg tcaatcaact tccatgatgc accaacttca
    10861 tcccagtggc taaagttagt tgagttgtta tttaggacat cataaatcaa tttctcgtat
    10921 ggttctggag aagcaccagt tgcagtcgca tctgtacggt aatcaagtga gttaggagcc
    10981 aagttaaatt cttctcctac ttgcttccca tttaggctaa gagagaagcc ttctgttggt
    11041 tgaatataga tggtcaaaat atttggagca agtggttctc caaagataga atccatttgt
    11101 ttaaagacga tgttgacatg agttcctttt tcagtcagtc gtttacctgt acggaaaaag
    11161 aaaggaacac tacggaatcg atcgctgtct acaaagaagg caccagatgt aaaggtttca
    11221 gttgttgatt ctggattcac atttggctcg ctacgataag agatgtattt catgccatca
    11281 atcttaccag agcggtattg cccacggata aagtgttctt tgagttcttc atcagttgga
    11341 tgatagaggt ttttaaagac cttaatcttt tcagcacgaa tctcgtcttt tgtgaagatt
    11401 gctggtttgt ccatggcgag gagcgaaaga agttgtagag tgtggttttg gaccatgtca
    11461 cggagggcac cggattggtc atagtagcca ccacgttctt ctacacccaa gcgctccgca
    11521 aaggtaattt gaacattgtc gataaaatcc ttgttccaaa cgttttcaaa aatcaagttt
    11581 gcaaagcgaa ctgcaaagat gctttggatc atttccttac caagataatg gtcgatacgg
    11641 aaaatttgtt cttcgtcaaa tgttgctagg agttcgtcat tcaacttgct tgcagttgcg
    11701 taatctgtac caaatggttt ttcaacgatc aagcgctcaa aacctttgcc atcgacaatg
    11761 ttttcagatt tgaggtgttt ggcaatggtt ccaaagaact gaggtgccat agacaagaag
    11821 aagagcttat tgtgttcagc ttggtatttt tcattaagct cagcttgtaa ttgacgcaaa
    11881 gcaatataat gttccgaatc attgacatca tggctttgat agtagaagtg gctagcaaat
    11941 tcttgggctt gctcggtact atctgccaaa tcaaggatgg actcgacaac tacagattca
    12001 aaatattcct tactccaagg tctacgggca gttccaataa cggcaaagtg cttggaaaga
    12061 ttgccggatt gatatagtct aaaaagggaa gggtagagct tgcgtttagc caggtctcca
    12121 ctcgcaccga aaattgtaac aataacctta gatgacatct agctacctaa tttctatttt
    12181 tattcctagt cttgctaggt atgaggaaac ctcatttcat aaacttaatt ctaacataat
    12241 tttccgaaaa atcaaaaatt ccaatacgag gtagaaaaac tgcaaggaaa tccttacagt
    12301 ttgagtttag acgtttaaga ccttatctaa gaactctttc agacgagggt gttgtgggtt
    12361 atcaaagatt tggtcaggtg ttccgtcttc aaggaactcg ccatctgcag taaagataac
    12421 gcggttggca acctgacgag caaatcccat ctcatgggtt acgataatca tggtcatgcc
    12481 ttgctcagcc aattccttca taacgttaag tacgtctcca accatctcag ggtcaagggc
    12541 agaagttggt tcatcgaaga gcatgatgtc tggattcatt gctaggccac gagcgatggc
    12601 cacacgttgt ttttgaccac ctgataggtt atctggattg gcattagctt tatctgctag
    12661 tccaaccttt tcaagcaact ccattcccaa ttcctcagct tcttccttag tcatcaactt
    12721 gtgctcaata ggagcaaagg tgatgttgtc caatacagac atatgaggga agaggttgaa
    12781 gtgttggaat accatgccga tattttcacg gacgtggtca acattggttg ttttttcagt
    12841 taaatcatag ccgttcacag tgatgtgacc gctagtgact tcttctaaaa gattgaggct
    12901 acggaggaaa gttgacttac cagaacctga aggaccgatg atacaaacaa catctccttc
    12961 atagaactta gtcgtaattc cttttaggac ttcatttttt ccatagtgct tgtgtaaatc
    13021 atttacatca atttttaatt ttgccattaa cgaatcctct tttctaagcg tttcgctagt
    13081 ctagtcaaaa gtgtgataat tacaagatag aagatagcaa ggattgcata catcttgaaa
    13141 ctttggtagt tacgagcaat gataatctta ccagtttgga agagttcaac caaaccgata
    13201 gcagatacga tagttgtatc tttaagagcg ataacgaatt ggttgacaaa gtttggcaac
    13261 atcaatttag ttgcttgtgg caagataatc ttacgcatgg tttttccata agagataccc
    13321 aagcttcggc tggcttccat ttggccaact ggaacggcct gaataccacc acgaacgatt
    13381 tcagcgatat aagcagccgc attgagtgag agggcaatgg ttccagctac aaagtcgtta
    13441 attgggcttt gttggcctgt gatagactcg atgaagtttg gaattcccca gaagatgaag
    13501 gctgcaagaa tcatcaatgg aataccacga ataacgtcaa cgaaaatctc agagatgacg
    13561 cgaagagatt tgtatgggct aacgctaaac ataccgaaga taattccgat gacaatggca
    13621 atagcaaatg agataagagc tagagcaaga gtgataccaa gaccgctaag gagttgtttg
    13681 tagttgtttt gaagcaagcc ccagagcgtt gtttcgtcaa cagtacttgt tgaagcagtt
    13741 gaagattcgc tagctaggta tttgtcaaga atcttttgga attcaccgtt tgctttaagg
    13801 tttgcaagtc cgttgttgaa catttcaatc agttctggat ttgctccttt tttaacggca
    13861 aaggctgttt caccgattgg agttccagag attggagttt tcaatttttg accttggctg
    13921 atagaatatt tgagaacagg ttcatcatcc ataacggcat caatggcacc agtgtttaaa
    13981 ctgtcataca ttgaagaacc atcagcaaag gttttgattt tgtaaccgta tttgctttga
    14041 ttttctgtta ggaaggtttg agaagcagtt ccgtttttaa caccgactgt ctttcctttt
    14101 agatcttcat aagaagcaat attgcttgat tctttgacac caagaatggt attagcagtg
    14161 tagtatgatt ctgagaagtc aaaagttgcc ttacgagcat ctgtgacaga cataccagca
    14221 atgataccat cggcttgacc agcttggaca gcactgatag cagcatcaaa accagggttg
    14281 gtgatttcaa tttcaaaacc ttggtcttta gcgattgcct taatcaattc catatcaata
    14341 ccagtgtatt ggttgcttga attttggaaa acaaaaggtg caaaagaaga atcgctggca
    14401 atgatatatt tagccttaac aggaatagct tttaatcctg cgagagtagt tgtagttggc
    14461 actgctgaag atgatgaagc agtccatttc ttgataattt tatcaagact accatctttt
    14521 ttcatttcag ccaaggcttg gttaaattca gtaaccaggt gctcgtattt acttcctttt
    14581 ttcacaccga aagcaaaact tcctacagct tcaccatcca tttcaatatg gaggtcttga
    14641 ccttggttaa tggcatattc gataacaggt ttgtcatcca tcatggcatc gatggcacca
    14701 gcactcaagc tgttgttcat taaatcacca gtgtcaaatg ttttaatagt aaagccgtat
    14761 ttatctttga ttgtttcaag gaaacgttga gcggcagttc cgtttttaac accaacggtt
    14821 ttgccagtta attggtcgta cttgctaatt ttgtgtgact ttgtagtagc aatgacaact
    14881 tttgtatcat agtaagtatc agacatggtg aagacttttt cacgttcttt agtctttgtc
    14941 atccctgcca tgatagcgtc ggcttgccca gcttgaaccg cattgactgc tgcgtcaaat
    15001 ccaggatagg acatctgaat gttccagcct ttaatctcag cgactttgtt aataatgtca
    15061 acatcaattc ctttataagt ttgatctgaa tctttaaact caaaaggtgc ataggcggta
    15121 tcagaaacaa tcttaatcgt ttctgctttg gcaataccta atgagaaaat tgggaataaa
    15181 attagcaaaa atgctagaaa ttttttcttc atttttagtc tccttttccg aatattctct
    15241 cattatatca gaaaaagtaa aaaaaggcaa atttttatat ttttcgtgtc agaaaatata
    15301 acattgattt ttccttttct ttcttgaatt gctattaaaa attgctataa taatactata
    15361 tatagaagaa aagaggacgg ggatatgaag aacaaaagaa tatttaaaga cttccaagct
    15421 tcaaaaatga atttaaacct ttacacaagc cccttgttag cctttgtttt tgtcttcata
    15481 ggagagtttg tggcttatac tttatatggt attagtttgt tagctctcat cggacttgct
    15541 agaaattttg gagaggctgg tcaaaatctt gcaagctact tgcagacctt gcatcagagc
    15601 ttgacggata aaacaagtga ctttcgttta attttaggat tactggcctt tggttttatt
    15661 cttaacactg tgttcagatg gacaagaaaa gttgagaaaa gacctattcg aaccttggga
    15721 ttttatagag agaattgcct cagcaatctt ctgaaaggat ttagtctagg cctggcactt
    15781 tttcttctga ccttgttaag tttagtggtc ttaggtcaat atcgtttgga atccattcac
    15841 ttgaatcctt attatcttgc ctttgtcgtc tttactatcc cattttggat tttacagggg
    15901 acagcagaag aagtggtggc ccgtgcttgg ctacttcctc aattggcctc aagaaccaat
    15961 ctaaaactag ctattcttat atctagcctg ttctttaccc tgcttcatat gggcaattct
    16021 ggcctcaccc ctctatctct agtaaatctc tttttattcg gagttgccat ggctctttac
    16081 cttctcaaaa ctgatacagt ttggggtgtt gcaggtattc atggtgcttg gaattttgct
    16141 cagggtaatc tctttgggat tttagttagt ggtcaaccgt caggaacgtc tctgatgacc
    16201 tttttaccac aaggcaatca agattggcta tcaggtggtt cttttggcat agaaggttcc
    16261 attatgacaa gtctggtatt actactgctg attgtctatc ttgctaataa attaaagaaa
    16321 gaaaatgaaa ggatgtgact tcggtccgtc cttttcttcg tgaaaatact ataagtatgc
    16381 taaaatagga atagcacatg gagagaggat tcttatgatc aatcacatta cagataatca
    16441 atttaaacta gtatcaaaat atcaaccatc aggagatcaa ccccaagcta tcgagcagtt
    16501 ggtggataac attgaggggg gagaaaaagc tcagattctg atgggggcga ctggaacagg
    16561 gaagacctat actatgagtc aggtcatttc taaagtcaat aaaccaactc tggttattgc
    16621 ccacaataaa actctggctg gtcagctcta tggggagttt aaggaatttt tccctgaaaa
    16681 tgcagttgag tatttcgtat cctactatga ttattaccag ccagaggcct atgtcccttc
    16741 tagcgatacc tatattgaga aggatagttc tgtcaatgac gagattgaca agcttcgcca
    16801 ctcagctacc tcagcccttt tggagcgtaa tgatgttatt gtcgtggcct cagtctcttg
    16861 tatctatggt ttgggttcgc ccaaggaata cgctgatagt gtcgttagtc tccgtcctgg
    16921 tctagagatt tctcgtgata aactcttgaa tgacttggtc gatattcagt ttgaacgcaa
    16981 tgatattgat ttccaacgcg gaagatttcg cgttcgtggg gatgtggtag agattttccc
    17041 agcttcccga gatgaacatg cctttcgagt agaatttttt ggagacgaaa ttgaccgtat
    17101 tcgtgaagtt gaggctctga caggtcaggt gttgggagaa gtggatcatt tagcgatttt
    17161 cccagcgaca cactttgtga ccaatgacga ccacatggaa gttgccattg caaagattca
    17221 ggccgagttg gaagaacaat tagctgtctt tgaaaaggaa ggtaaactgc ttgaagccca
    17281 gcgtttgaaa cagcggacag agtatgatat cgaaatgttg cgtgagatgg gctataccaa
    17341 tggggttgaa aattattctc gccacatgga tggacggagc gaaggagagc ctccttatac
    17401 gcttctcgac ttcttcccag atgatttctt gattatgatt gacgagagtc atatgaccat
    17461 agggcaaatc aagggcatgt acaatggaga ccgttcgcgt aaagaaatgc tggttaatta
    17521 tggtttccgt ttgccgtctg ctttggacaa tcgtcctctc cgtcgggagg agtttgagag
    17581 tcacgttcat cagattgttt acgtttcagc gacacctggt gactatgaaa atgaacagac
    17641 cgagacagtg attgagcaaa tcattcgtcc aacgggactc ttggatccag aggtggaagt
    17701 ccgtccgact atgggacaga ttgatgacct cttgggtgaa atcaatgccc gcgttgaaaa
    17761 aaatgagcgt acctttatca caactttgac caagaaaatg gcagaggact tgaccgacta
    17821 cttcaaggaa atgggtatca aggttaagta catgcactcg gatatcaaga ccttggaacg
    17881 gacggagatt atccgtgacc tgcgcttggg tgtctttgat gtcttggtcg gaattaacct
    17941 gctccgtgaa ggaattgacg ttcctgaagt gagcctcgta gctattctcg atgctgacaa
    18001 ggaaggtttc cttcgcaacg aacgtggact catccagact attggacgtg ctgctcgtaa
    18061 cagtgaaggc catgtcatca tgtatgcaga cacggttacc cagtctatgc aacgtgctat
    18121 cgatgaaact gcccgccgtc ggaaaattca gatggcctat aatgaagagc atggtatcgt
    18181 accacagaca atcaagaaag aaatccgtga cctgattgct gtgaccaagg cagttgctaa
    18241 ggaagaggac aaggaagtcg acatcaatag cctcaacaaa caagagcgca aagaactcgt
    18301 caagaaacta gaaaaacaaa tgcaagaagc cgtcgaagta cttgactttg aactggcggc
    18361 tcagatccgt gatatgatgt tggaagtcaa ggccttggat taggggaata gtatgattta
    18421 tttaagaaag ttaaagagag aagatttgat gtctttatgg gaaatggctt attcacaact
    18481 taatccagtt tggaaacagt atgatgctcc ctattatgat gattatcagt atttttcaaa
    18541 ttttaaagaa ttcgaactac aaaaatcaga atccatttta agcaactcaa atcgccttgg
    18601 tatttttgtt gatgataaac tagttgggac tgtttcgcgt tattgggtat gtaaacaaac
    18661 aagatggatg gaattgggaa ttggtattta tgataaaaaa ttctggaaca ctggtattgg
    18721 gaaagttgct atgttgcagt ggatagatag gacgtttcag gattacttgg agttggagca
    18781 tctgggtttg acaacttggt cagggaatct tggtatgatg aaacttgctg aaaaattaag
    18841 aatgaaaaaa gaagctcata ttccaaaagt tcgttattat caaggtaaat attttgatag
    18901 tattaaatat ggtattttga gagaagactg ggagaaaaca aatgacggtt attatcaaat
    18961 caatggaaac tcctgaagag atagaaggta agccccttgt tcactggcaa acgtggagag
    19021 aggcttatga tggccttttg cctgcagaat ttcaggagac aatgacatta gaaagatgtc
    19081 gattctttag tcaaaagtat ccagaaaata cattgattgc gatggatggt atgaaggtag
    19141 ttggttttat cagttatggc aactttcgtg atgagactat tcaagctggc gaaattattg
    19201 ctttatatgt tttaaaagac tattatggaa aaggtatcgc acaaaagtta ataaaagcag
    19261 ctttgattgc tcttaatcat ttttctgaaa ttttcttatg ggtattgaaa gataataagc
    19321 gcgcaattgc tttctatcaa aaaatgggct ttacttttga tgaacaagaa aagatacttg
    19381 aacttggaaa gcccataaag gaaaaacgga tggtattcta ttctaaataa ttttaaaaag
    19441 tagaagctaa tggtactggt atcaagtcta aaaatttaat aaattagaaa gtgagtaaat
    19501 ttatgtctcg agcacaatta acgattttaa caaatatttg tctgattgaa gatctcgaag
    19561 ctcagcgcgt ggtgatgcag tatcgcgctc ctgaaactaa tcgctggtct ggttatgcct
    19621 ttccaggagg ccatgtagaa aatggcgaat ctttcgcaga gtctgtcatt cgtgaaatct
    19681 atgaagaaac agggttgact atccaaaatc ctcaacttgt cggcattaaa aattggccac
    19741 tagatacagg tgggcgctat attgtcgttt gttataaggc aactgagttc tctggtaccc
    19801 ttcgctcttc agatgaagga gaagtttctt gggtgcaaaa agaccagatt ccaaacttgg
    19861 atctggccta tgatatgcta cctttgatgg agatgatgga agcatcggac aaatctgaat
    19921 ttttctaccc tcgccgtaca gaagacgatt gggaaaagaa aattttctaa tcctttacta
    19981 aataacctag ctgatccaag gcctcctcga tatagtggag gtcttgttgt gtttcggctt
    20041 cgactaggtg gtaatggaca ccatctgtca attcagataa aggtttaaaa tcagaatgct
    20101 cgacttgttc tagaaaatgt tgaacgtctc ggcggcaaga cagtttaagc aaggtttcaa
    20161 tttctccata aacgggatgg tcaatcaaag tattctggac atgcccacca ttatcgacaa
    20221 tagcaaggag ttcctgaccg atttcttcaa cttcatgttt cactttgaaa agtttgtgaa
    20281 cataaggatt ggtatcaatt tgcttataga tgtagccacg attggtggat aggataggag
    20341 cgccatcggc tctcaaaatt gcaatgtcct gcacaatgac ctgacgtgtg acatgaaaat
    20401 gttccgccaa actttggcca ttaagggctt taggagcttc tttcaagagt tggagcaggg
    20461 cttgtttgcg atcttttgtc atagcttttc cttttaacgg cgttttcgaa gcactttata
    20521 gacagctagt gctaatgtat agtctaccat actatggata attgtgccaa atccaactag
    20581 tacaaataga acatagaaca tgttttctac attggtaccc gaagttgcgt aaaaaaggac
    20641 acaggctaat acttcagcaa gggcatgaac aacagccaaa acaaaattga aaacccagga
    20701 agattttggt ttatctaggg tatcggggaa tttttgtagg taaagagatc ctaaagcacc
    20761 aaaagatata tgggaaaaag cccgaaaaac tataaccatg ggatagccag ccatcaaaaa
    20821 tccaaaacta gaggctagga tgacaaaaac tgccatcaag ggcgacaaga acatggctat
    20881 aaaaatagcg atgtggctcc ccaaagtata ggaagcaggt ggaatgacaa tcttgaaagg
    20941 cataacaatt ggaatcaaaa tcgcaatagc cgttaaaagg gctgtcattg tcataaattg
    21001 tgtctttttc cgtgtattca caagaatctc ctttttaact gcatatacac tagtatggta
    21061 caataaacca gacaataaag caagaattta cttgggttta tagatcattt tttagttaaa
    21121 agttatagta gatggaaact agaatagtcc acctctactt ctaaaacatt gttagcgatt
    21181 tgactgtcct gatcgatttg tcctgttctt atttcgtttt actatagtaa agatttcatt
    21241 aaaaagaaac tgtatagagc aaaatctcca ccttcaggtt tgaaagcgga gattgttttt
    21301 attttttcaa ggtttgtagt cgtggaacaa tggctagggt tagaattgca gaaatgacca
    21361 attcagcaat tgaatttgtt gagataacgg ttgccagaag aagttggata tttccattat
    21421 aaacatttcc aaataggaag aagattcctc caaggacaaa gatagtattt gtcaaggaac
    21481 caagggctcc agctaaaatc agaccagtct tgtttttcat cagtttatag actaagtaag
    21541 gagttaaacc aatcaaaata cgtgggacga tggcaatgat agctgagtag atgtttccgt
    21601 ttggtacgaa gggagagaag aggtagcttg tcggtagaat cgtaatcgtg ttaaccgtca
    21661 agctaagtaa tcccatcaaa aatccaagtg taaccccaac tcgtggacca taaataatgc
    21721 tggcaataat gacaggaata tgaacaatgg tcggtttgat tggaaatgga aaaaggttaa
    21781 agataagtga gctcagaaag tgtatcacga gcatggtagc aaaaaagata gcaatgggtg
    21841 caatattaga gcgttttttc atcgatagtt tcctttattc tttctaaaat aattgtgagg
    21901 tcagctaaag ctcctcgtcc gtggtctcca caagctagta gggattcctt aggagcaatc
    21961 agctgatagc cgtaggtttc taatgttttc agattattct gagttactgg atggtcatac
    22021 atttttgtat tcatagcagg agctattagt ttgggaatat gacttggtag ggctagagct
    22081 gtactggtta ccatgttgtc cgcaaatccg tgagctagtt ttgcaatagt gttagcagtt
    22141 gcaggtacca cgataaataa atctgctttt tttccaagtt cgatatgatt gacctgatca
    22201 ggatagggtt ccttcatgac atccaagtgg acaggattct gtgagagtac ctgtagtgtc
    22261 aaaggttgga taaactctgt agcagcctga gtcattaaga cagtgacttg atggccttgt
    22321 ttttttagag aactgactaa atctgccgac ttataagagg cgattgaacc cgttacagcc
    22381 aagagaatgt ttgccatagt tttcctttct aagaatgata ggcttgaatt ttttcaagga
    22441 ggagttctgc aatttcttct ttagtctgga ctgtttgaag ctgatttttc tcaacaaata
    22501 tagctcggtg ctgatctgct gaaatttgag tcaggtcatt cgcgatgatt aaatctgctt
    22561 gattcttgat aagacttttt cgtgcaatgt caaccagatg atcttcggta acatcaacca
    22621 gcagtttgaa accaatcaga tgaatagtgg gattccattc cttgactagg gatatgattt
    22681 tgggtgtctt tttaaggaac aaaacctgaa cctcatcagt tgaagaaatc ttggcctgat
    22741 gattctgctt gcttaaaaat tcttttagat tggagctagc ctgaacttcc tcaagccctg
    22801 tcatataaac aggagtgtag tcagaaacag ccattgagtg gatcaagacc tgataatcct
    22861 gaacacgttc ttgcatttct attagaaggt ccttggtatt ggtaatttct cgaatactta
    22921 ggttaggatg aggctctggc ttcagagctc gttttgtcgt aattaaacaa acttcatgcc
    22981 ctgcagaaag caaagtctct gtgataattt tccccaagtg acctgtagaa tggttagtga
    23041 tagagcggac gctatcgata gcttcactgg taccgcccga tgtaactaaa attttcatag
    23101 cactattgta cacaaaaata agcggtaagt aaaatgaaag tgataaattt ttggtaaaaa
    23161 cgaagattta ctatagtttc aaactataaa gccatataaa atttaagaaa ggactctaaa
    23221 agccttaaaa acagagatat ttacgaacgt ttagagagtt ttaggatgtt aaaaatcttg
    23281 ttttgtgata taatgaatta tcatataaga ggttagagga attttgaatg aaaacagata
    23341 ttgaaatcgc acagagtatt gagttgaagc caattgttga tgttgtagag aaacttggta
    23401 tttcttatga cgatttggag ttgtacggaa agtacaaggc taaactcagc tttgataaaa
    23461 ttcgtgcagt tgagagcaat ccagtcggta aattgatctt ggttactgcc atcaacccaa
    23521 cacctgcagg tgaaggaaag tcgacgctta ccattggtct tgcggatgcc ttgaacaaga
    23581 ttggcaagaa aaccatgatt gctatccgcg aaccgtctct tggtccagtc atggggatca
    23641 agggtggtgc tgctggtggt gggtatgcac aagttctgcc aatggaagac atcaacctcc
    23701 actttactgg agatatgcat gctattacaa ctgccaacaa tgccctttct gccttgattg
    23761 acaaccactt gcaccaaggg aatgagctgg aaattgatca acgtcgtatc ctctggaaac
    23821 gcgttgtgga cttgaacgac cgtgcgctcc gccatgtgac tgttggtctt ggtggtcctc
    23881 taaacggtat tccacgtgag gatggttttg atattacagt tgcttcagaa atcatggcaa
    23941 ttctttgctt ggcaacggac atcgaggact tgaaacgtcg tttggcgaat atcgttattg
    24001 gttatcgcta tgaccgtacg cctgtttctg taggtgattt gcaggttgag ggtgccttgg
    24061 ctttgatttt gaaggatgct attaagccaa acttggttca gacaatttac ggtacacctg
    24121 cctttgtaca cggtggtcca tttgccaata tcgctcatgg ctgtaactct gttttggcga
    24181 cgacaacagc ccttcacttg gctgattaca ctgttactga agctggtttt ggtgcggacc
    24241 ttggtgctga gaaattcctt gatatcaaga caccaaactt gccaacatct ccagatgcag
    24301 ttgtcattgt cgcaaccctt cgtgccctta agatgaatgg tggtgtggct aaagacgctc
    24361 tgactgaaga aaatgtagag gcagttcgtg caggttttgc taacttgaaa cgccacgttg
    24421 aaaatatccg taagttcggt attccagcag ttgtagctat taacgaattt gtatctgata
    24481 cagaagctga aattgcagtc ttaaaagaac tctgtgcctc aatcgatgta ccagttgaat
    24541 tggctagtgt ctgggctgat ggagcagaag gtggagtagc acttgccgaa acagttgtta
    24601 agacaattgc tgaaaatcca gctaactata aacgtttgta cgataatgcc ctttctgtcc
    24661 aagaaaagat tgaaaaaatt gtcactgaaa tctatcgtgg tagcaaagtg aactttgaga
    24721 agaaagctca aacacaaatt gctcaaatcg ttcaaaacgg ttgggacaaa ttgccaatct
    24781 gtatggctaa aactcaatac agtttctcag acaatccaaa tgcgcttgga gcaccagaaa
    24841 actttgaaat taccattcgt gaattggtac caaaattagg tgcaggcttc atcgttgcct
    24901 taactggtga tgttatgacc atgccaggtc ttccaaaacg tccagcagct ctcaacatgg
    24961 atgttgaaag cgatggaact gtactaggct tgttctagtg gattgaaatt gactttaagt
    25021 gagtttggaa ataatatcca agctcatttt ttctcagact gcaagcagtt catcaataag
    25081 atttatactc ttcgaaaatc tcttcaaact acgtcagctt caccttgccg taggtatatg
    25141 atactgactc tgtcagttct atccacaacc tcaaaacagt gttttgagca acctgcggct
    25201 agcttcctag tttgctcttt gattttcatt gagtataagt agatagaaaa gttatatact
    25261 atctattgaa aatattataa atcagataca aagacaggtg aaaccttctg tgttatacta
    25321 gagatatgtt agatttgaaa gaatacggta tcgtcatgtg gccggaggag aaagtcattt
    25381 ctttccgtga gaaacttctc gcttggtatg atgaaaacaa aagagatttg ccttggagga
    25441 gaagtaaaaa tccttatcac atctgggtat ctgaaatcat gcttcagcag accagggtgg
    25501 atacagttat cccttactac gaaagattcc tggactggtt tccaactgtc gaaagtctgg
    25561 caactgcgcc tgaggagagt ttactgaaag cttgggaggg cttgggctat tattctcgag
    25621 ttcgcaatat gcaggctgca gcccagcaga ttatgactga ctttggtggc caatttccaa
    25681 atacctatga aggaatttcc agcttgaaag ggattggacc ttacacagca ggagccattt
    25741 ccagtattgc ttttaacttg cctgagccag ctgtagatgg taatgtcatg cgggtcttgg
    25801 cgcgtctgtt tgaagtcaac cacgatattg ggattccaag taatcgaaaa atttttcagg
    25861 caatgatgga gatcttgatt aatccggatc gtccgggtga ttttaatcaa gccttgatgg
    25921 acttagggtc tgatattgag tctcctgtaa atcccagacc tgaagaaagc ccagtcaagg
    25981 actttagtgc ggcatatcag aatggaacca tggaccgtta tccaattaaa tctcctaaga
    26041 aaaagccggt tcctatttat cttaaagcat tagttgtgaa aaattctcaa ggacaatttt
    26101 tacttgaaaa aaatgaaagc gaaaagctct tggcaggttt ttggcatttc ccccttatag
    26161 aagttgataa cttttcgcaa gaagagcagt ttgacctctt tcatcaggtt gcggaagaaa
    26221 gtgtgaactt tggccccagt ccagaagaga gtttccagca ggactatgac ctagatgttg
    26281 attggcttga tgtttgtttt gatacagtcc agcatgtttt tagtcatcga aaatggcatg
    26341 tacagattgt agcaggtcag gtgagtgact tccatgattt ttcagatagg gaagttcgtt
    26401 ggctttcacc agaagaattc aagaattacc cacttgccaa accccaacaa aaaatctggc
    26461 aggcttatgc acaagccaac ttagacagta gccaagacta gctattgtgt cttctgacta
    26521 ttttttggta taatagtaga gaaaaaggtg aacatatgaa aaaaatacta attgtagatg
    26581 atgagaaacc aatctcggat attatcaagt ttaatatgac caaggaaggt tacgaagttg
    26641 taactgcttt taatggtcgt gaagcgctag agcaatttga agcagagcaa ccagatatta
    26701 ttattctgga tttgatgctt ccagaaattg atggtttaga agttgctaag accattcgta
    26761 agacaagcag tgtgcccatt cttatgcttt cagccaaaga tagtgaattt gataaggtta
    26821 tcggtttgga acttggggca gatgactatg taacgaaacc cttctccaat cgtgagttgc
    26881 aggcgcgtgt taaagctctt ctgcgtcgtt ctcaacctat gccagtagat ggtcaggaag
    26941 cagatagtaa acctcaacct atccaaattg gggatttaga aattgttcca gacgcctacg
    27001 tggctaaaaa atatggcgaa gaactagact taacccatcg tgaatttgag cttttgtatc
    27061 atttagcatc gcatacaggt caagtcatca cgcgcgaaca cttgcttgag actgtctggg
    27121 gttatgacta ttttggtgat gtccgtacag ttgatgtgac tgtacgacgt ctgcgtgaga
    27181 agattgaaga tacgcccagc cgaccagagt atatcttgac gcgccgtggt gtagggtatt
    27241 acatgagaaa taatgcttga tttactgaaa caaaccattt ttaccagaga ttttatcttt
    27301 atcctgattt tgttaggttt catccttgtt gtgaccctct tattactgga aaatagacgt
    27361 gataatattc agttgaagca aatcaatcaa aaggttaaag atttgattgc aggagattat
    27421 tccaaggttc ttgatatgca aggtgggtct gaaatcacca atattaccaa taatttgaat
    27481 gacttgtcgg aggttattcg tctcactcag gaaaatctag aacaagagag taagaggcta
    27541 aatagtattc tgttttatat gacagatggg gttcttgcga ccaaccgtcg gggtcagatt
    27601 atcatgatta acgatacagc caagaagcaa ctggggttgg ttaaggaaga tgttctgaat
    27661 agaagcattt tggaattgct caagatagaa gaaaactatg aattgcgtga tttgattacc
    27721 caaagtccag aattgttgct agattcccaa gatatcaatg gcgaatattt gaaccttcga
    27781 gttcgctttg ccttgatacg tcgagagtct ggctttattt caggtttggt ggctgttttg
    27841 catgatacga cggagcagga gaaggaagaa cgcgaacgaa gactctttgt ttccaatgtt
    27901 agccatgagt tacggactcc tctgactagc gtaaaatcct atcttgaagc cttggatgag
    27961 ggggctttgt gtgaaactgt agcaccagac tttatcaagg tttctcttga tgagaccaac
    28021 cgtatgatgc gcatggtgac ggatctcctc catctttcac gtattgataa tgctaccagt
    28081 cacctagatg tggaactgat taacttcact gcttttatta cctttatcct caatcgtttt
    28141 gacaagatga aaggacagga aaaggagaaa aaatatgagt tggtgagaga ttatcccatc
    28201 aattctatct ggatggaaat tgatacagat aagatgacgc aggttgtcga caatatttta
    28261 aataatgcta ttaagtattc gccagatggg ggtaaaatca ctgtcagaat gaagacaact
    28321 gaagaccaga tgattttatc catttctgac cacggtttgg ggattcctaa gcaggattta
    28381 ccacgtatct ttgaccgttt ctatcgtgtg gatcgtgcta gaagtcgtgc acaaggtggt
    28441 acaggtctag gactgtctat cgctaaagaa attatcaaac aacataaggg ctttatttgg
    28501 gccaagagtg aatacggcaa gggttcaacc tttaccattg tgctccctta tgataaggat
    28561 gcagtgaaag aagaagtatg ggaggatgaa gtagaagact agaatgagtg aaataggctt
    28621 taaatacagt attttagcgt cgggttccag tggaaattct ttttatctgg aaacctcaaa
    28681 aaagaagctt ttagtagatg caggcttgtc tggcaagaaa attaccagtc tgctagctga
    28741 aattaaccgt aagccagaag acctggatgc catcttgatt acccatgagc attcagatca
    28801 tatccatgga gtaggcgttt tggctcgcaa gtatggtatg gatctttatg ccaatgaaaa
    28861 gacctggcaa gctatggaaa atagtaaata tcttggcaag gtggattctt cgcaaaagca
    28921 tatttttgaa atgggtaaaa ccaaaacctt tggagatatc gacatcgaga gttttggtgt
    28981 aagccatgat gcagtcgcac cgcagttcta tcgctttatg aaggatgata agagttttgt
    29041 cctcttgaca gatacaggtt atgtcagtga ccgtatggcg ggcattgtcg aaaatgcgga
    29101 tggttatctt atcgaggcca accatgatgt agagattttg cgatcaggtt cttacgcttg
    29161 gcgcctcaaa caacgaatcc tatctgacct tggtcacctt tctaacgagg acggtgctga
    29221 agctatgatt cggacgctag gaaatcgtac taagaagatt taccttgggc atttatctaa
    29281 ggaaaacaat atcaaggaac tggctcatat gaccatggtc aatcagctgg ctcaagctga
    29341 tctgggagtc ggagtagact ttaaggttta tgatacctca ccagataccg caacaccatt
    29401 gacagagata tagaaagaac gctgagaagg tgttcttttt atattgactg gacacctaaa
    29461 aagtaataca atggtgttac cattaaaaaa gggagcacaa aagatgacta ctattacatt
    29521 aaaagtttct gaagctgata aaacatttat gaaagcaatg gctaagtttg aaggagtttc
    29581 cctttcggaa cttattcgca ccaaaactct tgaagcccta gaagatgaat acgatgctcg
    29641 tgtggcagat ttagcctatc aagagtattt agaagacttg gaaaaaggag ttgaacccat
    29701 tacttgggaa gaaatgatgc atgatttagg cttgaaggat gaataatttg tataaattag
    29761 ttccaacaag acgttttatc aagcaattga aaaaattgga ccgttatacg cagaagctaa
    29821 ttacaaacta tttacaaacc aatgttttgg aagatccaag acgacacgga aaggctttgg
    29881 ttggtaatcg cgttggtcaa tggcgctata gaattggtaa ttatcgagtt atcgtacaaa
    29941 ttgtagatga tgaattagtt gttgctactc tagaagttgg tcatcggaga gatatttatt
    30001 aaattaaagc tgagtaataa cagtatagaa agtaaggaga gtaaaaattt gaagaaaaaa
    30061 tggttttttg cagattatta tgacacaaca attattttac ttgctttaat ctctgttatt
    30121 ctggtattac ttggatttgc tgagatgatt gatttggaca atccgcctta tagtattatt
    30181 gatttagtaa tctggggtgt ttttgtaatt gattatagtt ggcgcttttt tacgactaaa
    30241 agaaaatggc gctttattct tgaaaatatt tttgatttat tggctattct ccctttaaat
    30301 gctattttta cagtgtttcg attagggcgt atctttcgtt tagctaaact aacaaaatta
    30361 ctgaaactga ctcgtttact tagaataatt ggacttacag gtaaattaga aagaaaaatt
    30421 agtagattct tacggacaaa tggcctgatt tatatcttgt atgttaatat ctttattgtt
    30481 ctagtaggga gttcgatttt atccgttgtt gaagaaaaat ccttctcaga tagtctttgg
    30541 tgggctcttg tgacagtaac tactgttgga tatggggata ttgttcctgc ttccattttt
    30601 gggaaatggc tagcagtttt actgatgctt gtcggtattg gaacaatagg gatgttaaca
    30661 agtgctttga cgaacttttt tgtaaaggat aatccagatg aacagataaa acttgataaa
    30721 ctcaaagatg aattatcgag ccaaagaata ttactagaga aacaatctaa aaagatagaa
    30781 gaactacata aaatgataca agatttgatt gaaaaaacat aataaaaata aagatgagac
    30841 aaagtttgag ctgaggagaa atcaagtaag ttttgacaca atagaacgca tattatcagg
    30901 tataaaaact tgatactatg cgttttatag agaaataaaa taaaatctga acaaatcaat
    30961 taggaattta aagcatttta taacaacgtt ttagagtgat ggggtgctat ttcaacttca
    31021 acctactata atacagaaaa aaacaactcc ctgatgattc aaggagttgt ctatagttaa
    31081 attagttttt agaagcttct tggaattctg gatttttcca tgcttcgtca ataatagctt
    31141 gcaattcttt agcagatgct tgcatttttt gagtttctgc atcgttcaat ggaatgttta
    31201 ctggacgaac gataccatgt gcaccaacaa cagctggttg accgataaag acattctcaa
    31261 ctccgtatag accttcttgg aatactgaaa gtggaagtac tgcgttttca tcgtcaagga
    31321 ttgctttagt gatacgagca agggctactg cgataccgta gtatgttgca ccttttttgt
    31381 tgatgattgt gtaggctgca tcacgaacac cttcgaacaa ttcaatcaat tcagcttctt
    31441 gaacattttg agtgtcttta aggaattctt caaggtttac accagcgatg ttagcgtgtg
    31501 accaaacagc gaactcagag tcaccgtgtt cacccatgat gtaggcgtgc actgaacgag
    31561 catccacatc caatttttca gcaagtgctt gacggaaacg agctgagtca agtgaagtac
    31621 ctgaaccgat aacgcgttct ttagggaaac cagagaattt ccaagttgag taagtcaaaa
    31681 cgtcaactgg gttagcagca acaaggaaga tacctttgaa accagattca acaacttgag
    31741 ttacgattga tttgttgata gcaaggtttt tacctacaag gtcaagacga gtttcacctg
    31801 gtttttgagg tgcacctgca gtaatcacaa caaggtcagc gtctgcacag tcagagtatt
    31861 gagctgcata gattttttta ggtgaagtga aggcaagggc gtgactaagg tcaagcgcat
    31921 caccaacagc tttttcatgc aattgtggaa tttcgataat tccaagctct tgtgcaattc
    31981 cttggttaac aagtgcaaaa gcgtaagatg aacctacagc accatcaccg acaaggataa
    32041 cttttttgtg ttgtttagtt gaagtcattg ttttaaacat ctccttaatt ttattagggg
    32101 attttcccta gacaacttca ttctatcact tttaaaaaac tttgtcacga atatgcctta
    32161 tagttctcga tgtaaacgtt ttagtggttt agaggctgaa atagatggga atttatggta
    32221 taatgttgtt acttactaat tgtgaaatga ggcatttatt aatgcaggat aaaaatttag
    32281 tgaatgtcaa tctgacaaag gagatgaagg caagttttat cgactacgcc atgagtgtta
    32341 tcgtagcgcg agctcttcct gatgttcgag atggcttaaa acctgttcac cgtcgcattc
    32401 tctacggaat gaatgaattg ggtgtgaccc cagacaaacc ccataaaaaa tctgctcgta
    32461 ttacagggga tgtcatgggt aaatatcacc cacacgggga ttcctctatt tatgaagcca
    32521 tggtccgtat ggctcaatgg tggagctacc gttacatgct tgtagatggt catgggaatt
    32581 ttggttccat ggatggagat agtgctgccg ctcaacgtta taccgaggca cgtatgagca
    32641 agattgctct ggaaatgctt cgtgatatca acaaaaatac agttgatttc gttgataact
    32701 atgatgccaa tgaacgggaa cccttggtct tgccagcgcg ttttccaaac cttttggtta
    32761 atggagcaac tggtatcgcg gttgggatgg caaccaatat tccacctcat aatctgggtg
    32821 aaaccattga tgcagtgaag ttggtcatgg ataatcctga agtgactacc aaggacttga
    32881 tggaagtctt gcctggacca gattttccaa ctggtgctct tgtcatgggg aaatcaggta
    32941 tccataaggc ttatgaaaca ggtaaaggtt cgattgccct acgttctcgt acagagattg
    33001 aaacgactaa gactggtcgt gagcgcatcg ttgtaacaga atttccttac atggtcaata
    33061 aaaccaaggt gcatgagcat attgttcgct tggttcagga aaaacgcatt gagggtatca
    33121 cagcagtacg tgatgagtca aaccgtgaag gtgttcgatt tgttattgaa gtcaagcgcg
    33181 acgcctcagc caatgttatt ctcaataacc tcttcaaaat gacccaaatg caaaccaatt
    33241 ttggtttcaa tatgctcgct atccaaaatg gtataccgaa aattttgtct cttcgtcaga
    33301 ttttggatgc ttatatcgag caccaaaaag aagtggttgt tcgtcgtaca cgttttgata
    33361 aggaaaaagc ggaagcgcgc gctcatatct tagaaggtct cttgattgcg ctagaccata
    33421 tcgacgaagt gattcgtatc atccgtgcta gtgaaacgga tgcggaagct caagctgagt
    33481 tgatgagcaa gtttaagctt tctgaacgtc aaagtcaagc tatccttgat atgcgtcttc
    33541 gtcgtttgac aggtttggaa cgcgataaga ttcaatctga gtatgatgac ctcttggctc
    33601 tgattgcgga tttagcagat attcttgcta agcctgaacg tgtttctcaa attatcaaag
    33661 acgaattgga tgaagttaaa cgtaaatttt ctgataagcg ccgtacagag ttgatgattg
    33721 gacaggtctt gagtctcgag gatgaggact tgattgaaga atcggatgtc ttgattaccc
    33781 tttctaacag aggctacatt aagcgtttgg atcaggacga gttcactgct caaaaacgtg
    33841 ggggtcgtgg tgtccaagga acgggagtga aagatgatga ctttgttcgt gagttagtgt
    33901 caactagcac ccatgatcat ctgctcttct tcacaaacaa gggacgtgtc tatcgtctta
    33961 aaggttatga aattcctgag tatggtcgga ctgccaaagg gctaccagta gtcaatctct
    34021 tgaaattgga tgaagacgaa agtattcaga cggttatcaa tgttgagtct gatcgcagtg
    34081 atgatgctta tctcttcttt acaacccgtc acggtattgt gaagagaacc agtgttaagg
    34141 agtttgccaa tattcgtcaa aatggtctca aagcgctgaa tttaaaggat gaagatgagt
    34201 taatcaatgt cttgttggca gaaggagata tggatattat cattggtacc aagtttggtt
    34261 atgcagttcg ctttaatcaa tcagccgttc gtggtatgag tcgtatcgcc actggtgtga
    34321 aaggtgttaa ccttcgtgaa ggagacacag ttgttggtgc cagcttgatt actgatcaag
    34381 atgaggttct tattatcaca gaaaaaggat atggtaagcg tacagtcgct actgaatacc
    34441 caacaaaagg tcgtggtggt aagggaatgc agacagctaa aattaccgaa aaaaatggct
    34501 tgctggccgg tcttatgact gttcaagggg atgaggattt gatgattatc actgatacag
    34561 gtgtcatgat tcgaaccaat cttgccaata tttcacaaac aggacgtgca actatgggag
    34621 ttaaagtaat gcgcctggat caagatgctc agatagtgac tttcacaacg gttgcggtgg
    34681 cagaaaaaga agaagttggg acagaaaacg aaacagaagg tgaagaataa tgtctcaaaa
    34741 aaataataaa aagaaaaaca agcgaaaaaa tctgctgaca aatatcctag caggatttct
    34801 gatattactg tcactggctt tgatttttaa tactcaaatt cgaaatattt tcatagtctg
    34861 gaataccaat aagtatcaag ttagccaggt atcaaaagaa aaattagaag aaaatcagga
    34921 tacagaaggc aattttgact ttgattctgt caaagctatc tcttcggaag ctgttctaac
    34981 ttctcaatgg gatgctcaaa aattaccagt tattggggga attgcaattc ctgaattgga
    35041 aatgaatttg ccgattttta aaggacttga taatgttaat ctcttctacg gagctggtac
    35101 aatgaaacgc gagcaagtaa tgggagaagg aaattatagt ctagctagtc accatatctt
    35161 tggtgttgat aatgctaata aaatgttatt ttctccttta gataatgcta aaaatggcat
    35221 gaagatttat ctaaccgata aaaataaagt ttatacttat gaaatacgtg aagtcaaacg
    35281 tgtgacaccg gatcgtgttg atgaagttga tgatagagat ggggtcaatg aaatcacatt
    35341 agtaacctgt gaagaccttg ctgctacaga acgtattatt gtcaaaggtg atttgaaaga
    35401 aacaaaagat tattcacaaa catctgatga aattctaaca gctttcaatc aaccatataa
    35461 acaattttat taatacaaat cagtgaaatc atggatttca ctgatttttt aagattttca
    35521 taaaaatata gtaaaatgaa ataagaatag gacgaatcgt tcaggacagt caaatcgatt
    35581 tctaacaatg ttttagaagt agaggtgtac tattctagtt tcaatctact ataaactttt
    35641 atgaaataca gaaaacgctt cctaaaacct aaagtttgtg atataattat caagaaaaaa
    35701 gatttaggag tttattatgg tttcttcaga atttatctca aagattgaat ttgcttgcaa
    35761 taagaaagaa agtctttata gtcaaagcaa atttaagtat gcgattcgtt cgatgttcgc
    35821 aggtgcattt ttaaccttca gtactgctgc aggtgcagtt ggggctgact tgattaataa
    35881 aattgcacca ggtagtggac gcttcctctt tccattcgtt tttgcttggg gcttggccta
    35941 cattgttttt ttgaatgccg agttggtcac ttcaaacatg atgttcttga ctgctggtag
    36001 tttcttaaaa aaaatctctt ggagaaaaac agctgagatt ttactatact gtaccttgtt
    36061 caaccttatc ggagccttga tagcagggtg gggctttgct cattcggcag cctatgcgaa
    36121 tctgacacac gatagtttca tctcaggtgt tgttgagatg aagttaggcc gctcaaatga
    36181 attggtcttg cttgaggcga ttttggcaaa tattttcgta aatattgcga ttctgtcatt
    36241 tattttggtc aaagatggtg gtgccaaact ttggcttgtg ttgtcagcta tttacatgtt
    36301 tgtattctta acaaacgagc acattgcggc gaactttgct tctttcgcga ttgtgaaatt
    36361 cagtgttgct gcggattcaa ttgccaactt cggtgttgga aatatgcttc gccactgggg
    36421 tgtgactttc atcggaaact ttatcggagg aggcctcttg atgggtcttc catatgcctt
    36481 cctcaataaa aacgaagata cttatgtaga ttaagaaaat gagcacgatt gagtcgtgct
    36541 tttttcattt tcaaaataag gtaatagcta tttcttatat caaaatatag aaaactgata
    36601 tttgtaaact ataactcaag gtgctacaat atccttaata aaatgatatg gaggtcacct
    36661 tatgacttgt gattttaaat ttgaaactct acaactacat gctggtcaag ttgtggctcc
    36721 agctactaag tctcgtgcag tgccgattta tcaaacaaca tcttttattt ttgatgacac
    36781 gtaggaaggt gctgatctgt ttgccttgag gaaaccaggg aacatttata ctcgtatcac
    36841 caatcctaca acagctgccc ttgaaggtgg tgttgaagcg ctagcaacag catcaggtat
    36901 gactgcagtg acttatacga ttttggcgct tgcccatgct ggtgaccatg tagtggctgc
    36961 ttcgactatt tacggtggaa ccttcaatct tttgaaagaa ccccttcctc gttatggtat
    37021 cacaacaacc tttgtcgatg ttgataattt ggaggaagta gaagcagcta tcaaagacaa
    37081 taccaagctt gtcttgattg aaaccttggg taactccttg attaatattc cagacctgga
    37141 aaaactggca gagattgctc ataaacatca aatcccactt gtgtcagaca atacttttgc
    37201 aataccttat ttgattaacg tcttctctca tggcgttgac attgccattc actctgcgac
    37261 taagtttatc ggtgggcatg gtacaactat tggaggaata attgtcgata gtggtcgttt
    37321 tgactggacg gcttcaggga aattccctca atttgttgac gagggtccaa gctgccacaa
    37381 tttgagttat acttgtgatg tgggtgcagc agcctttatt atagctgttc gagttcaatt
    37441 gcttcgtgat acaggtgcag ccttgtcacc attcaatgct ttcctcttgc tacaaagact
    37501 tgaaacctct tcacttcgtg tggaacgcca tgtacaaaat gctgagacaa ttgttgattt
    37561 tcttgtcaac catcctaagg tagaaaaggt aaattatcca aaacttgcag atagtcctta
    37621 tcatgccttg gctgagaaat acttgccaaa agatgtcggt tcaatcttta ccttccatgt
    37681 caaaggtggc gaggaagaag cacgcaaggt cattgataat ttagaaatct tttctgacct
    37741 tgcaaacgcg gcagatgcta aatcgcttgt tgtccatcca gcaacaacca ctcacggtca
    37801 attgtcagaa aaagacctag aagcagcagg tgtcacacca aactaaattc gtttgtcaat
    37861 cggtcttgaa aatgtagaag atttgattga agacttgcgc ttggccttgg aaaaaattta
    37921 aagtaaaaga agataaacag tgggcttcga ctcactgttt ttgattttcc ctcaggcatg
    37981 atataatggt taaagaagtc tagaaagagg aacgatatga acgaaatcaa atgtcccaac
    38041 tgtggggaag tctttacagt aaatgagagt cagtatgccg aactcttgtc ccaagtgaga
    38101 acggcagagt ttgataagga actacacgat aggatgaagc aggaactggc cttggctgag
    38161 caaaaggcca tgaatgagca acagactaaa ctggctcaga aggatcaaga aattgcgcaa
    38221 ttacagagtc agatccaaaa ctttgataca gaaaaagaat tggccaagaa agaggttgaa
    38281 cagacaagcc atgaggctct cttggctaag gacaaggaag tacagctctt agaaaatcag
    38341 ttggctacct tgcgtttgga gcatgaaaat caactgcaaa agaccctttc tgacctagaa
    38401 aaagaacggg atcaggttaa aaaccaacta cttttgcagg aaaaggaaaa tgaattatct
    38461 ttggcttctg ttaagcaaaa ctacgaagcc cagctcaagg cagctagtga acaagtcgag
    38521 ttttataagg attttaaggc tcaacaatct acaaaagcga ttggggaaag cctagaacag
    38581 tatgcagaga gtgagtttaa caaggttcgt agtttcgcct ttccaaatgc ttactttgag
    38641 aaggataaca aggtctcttc gcgtgggtct aaaggggact ttatcttccg tgagtgtgat
    38701 gaaaatggag ttgaaatcat ttctatcatg tttgagatga aaaacgaagc agacggaaca
    38761 gagaagaagc acaagaatgc agatttttac aaggaattgg acaaggaccg tcgggagaag
    38821 aactgtgagt atgccgtttt ggtgaccatg cttgaggccg ataatgacta ctttaacaca
    38881 gggattgttg acgtcagcca cgagtatgaa aaaatgtatg ttgttcgtcc tcaattcttt
    38941 atccagttga ttggtctctt acgtaatgcg gcgctaaatt ccctaaaata caagcaggag
    39001 ttggccttgg ttcgcgagca aaatattgac attacgcatt ttgaggaaga cttggatgcc
    39061 tttaagctag cttttgctaa gaactataat tcagcttcga ctaactttgg aaaagctatt
    39121 gatgaaatcg acaaggccat caaacgcatg gaagaggtta agaaattcct gactacatct
    39181 gaaaaccaac tccgtctagc taacaacaaa ttggaagatg tctctgttaa aaaattgacc
    39241 cggaaaaatc caacaatgaa agcgaagttc gaagcactga agggggagta gaaagcaaaa
    39301 atgaacggta ttatcaactt aaaaaaagaa gcaggaatga cctcgcatga tgcggttttt
    39361 aaactgcgta agattttggg aaccaagaaa attggtcatg gtggaacctt ggatccggat
    39421 gtggtgggtg ttttgccgat tgcggttggc aaggcgacac gcatggtcga gtttatgcag
    39481 gacgagggta agatctatga gggggaaatc attctgggct attccacgac gactgaggat
    39541 gctagtgggg aagtggtcgc agaaacccct gttttgtctc ccttggatga aaagcttgtt
    39601 gatgaagcga ttgctagctt gactgggcct attactcaga ttccccctat gtattcggca
    39661 gttaaggtta atggtcgcaa gctctatgag tatgcgcgtg ctggtcagga agtggagcgt
    39721 ccagaacgtc aggtgaccat ttatcaattt gagcgaacaa gtccgatttc ttatgatggc
    39781 caacttgccc gattcacttt tcgtgtaaaa tgcagtaaag ggacttacat ccgtactttg
    39841 tcagttgatt tgggtgaaaa gcttggttat gcggctcata tgtcccattt gactcgtact
    39901 agtgctgctg gcttacaatt agaagacgct cttaccttgg aggaaattgc tgaaaaagta
    39961 gaggctgggc aattagattt tctccatcct ttagagattg ggacaggtga ccttgtcaaa
    40021 gttttcctaa ctccagaaga ggctacagaa gttcgctttg gtcgttttat tgagctagac
    40081 caaacggaca aagaactggc tgcctttgaa gatgataaat tgttagccat tctagaaaaa
    40141 cggggcaatc tctataagcc aaggaaggtt tttagctaga tcgtttagga ataaaaatcg
    40201 ggtgatagat aacaattgct tgataaaccc ccatactaat agtagaatgg ttttgggaat
    40261 tataatattc caattgttgc gagttgtaga tactcaaata atctatatag aaatttagag
    40321 gtgtgaaatg aagcaactta aaattctttc agataaatat ttagagtcca tgacaggttc
    40381 tggtgggaac ttaggtctag gatttggtgt gataattcca tgatgtgaaa tgagtttcga
    40441 gaaagggtgg agcaacttct tcaacaaaaa gaaataaatg aaaatagtga gttgagtcac
    40501 ctgtttcgtc ttgctataca aaatttagac agaaatgaaa aataccaatc ggtcatggcc
    40561 aatttgagtc aagggttgtc actttacctc atgacgcatc attaccaggc acctaagtct
    40621 gtcattgatt ttggtttatg gattgccaaa gctcctagcc aggaaagagg gagactggct
    40681 ttcttgcaga tgcttgctca aaccctacag ggctttcgtt aaaactgtcg aacatcagag
    40741 ggaagactct ggtgtttttt gctgatgaga ctataaattt tgtaaaaaat gtgatagaat
    40801 agacgacgga taaaataacg gaggatagca tgcaaaatag accaatcatt attggagtga
    40861 caggtggttc tggtggtggt aaaaccagtg tttcaagagc cattttatcg cattttcctg
    40921 atgaaaagat ttccatgatt gagcatgatt catactacaa ggatcagtct catttgacct
    40981 ttgaagagcg tgtcaaaacc aactatgacc atccttttgc ctttgataca gacttgatga
    41041 tcgagcagat taaggaattg ttggcagggc gtccggtgga catcccgacc tacgactata
    41101 cagagcatac acggagtagc aagacctatc gtcaggagcc tcaagatgtc tttatcgttg
    41161 agggcatttt ggtcttggag gacaagcgtc tgcgcgattt gatggatatc aagatttttg
    41221 tggatacgga tgacgatgtg cgtattattc gtcgtatcaa gcgtgatatg gaggaacgtg
    41281 gccgtagcct tgatagcgtt attaaccagt acttaggtgt ggtcaaacca atgtaccacc
    41341 agtttatcga gtcaactaag cgttatgctg atatcgtcat tcctgaaggg gttagcaata
    41401 ccgtggctat cgacctgttg acgaccaaga ttgcaaagat tttggaagaa gctcgaaaca
    41461 gcaaataatc acatgtggag gccttgcctc ctttttctat ttttccctca taatggtaca
    41521 taaatggaga tttttaggca tatttttggt ataataatac ccataaaaga gcaagtaaat
    41581 gaatagtagg tggagatgga aaagtattta tcggtaacaa ctttgaccaa atatctgaaa
    41641 atgaaattcg ataaagaccc atacttggaa cgggtctatt taactggtca agtttccaac
    41701 tttcgtaaac gacctactca ccaatatttc tccctaaagg atgaccatgc agttattcaa
    41761 gcgaccatct ggtctgggat ttatcagaaa ttagggtttg acctggaaga aggaatgaag
    41821 atcaatgtga ttgggcgtgt acaggtctat gaaccaagtg gtagctactc catcatcatt
    41881 gaaaaagctg agcctgatgg ggttggggcg cttgcgattc agtttgaaca acttaagaaa
    41941 aaattgacag aagaaggcct gtttcaagaa cgcttcaagc aagctctacc ccaattttct
    42001 aagagaattg gggtagtaac cagccgtagt ggagccgtta ttcgagatat tatcacgacc
    42061 gtcagcaggc gattcccagg tgttgacatc cttctttatc ctaccaaggt tcaaggtgaa
    42121 ggggctgcgg aggaaattgc tagaaatatt gcgcgtgcta atcaacggga cgatttggat
    42181 ttgctcatta ttggtcgtgg aggtggttct attgaggatc tctgggcctt taacgaagaa
    42241 attgtggtac gagctatttt tgaatctcgt ttgccagtta tctctagtgt ggggcatgag
    42301 acggatgtga ccttggcaga ttttgtggca gatcgacgcg ctgcaacgcc aacagcggcg
    42361 gctgaactgg caacacctgt gaccaagttg gatgtattag ctcatttgca aaatcaggaa
    42421 aaacggatgg caacggcagt ccgaaatgtt ctatctaaga aacaagaggc tttgaaaaaa
    42481 tgcagtcagt ctgttatctt tagacaacct gagcgcttgt atgacggtta tttgcaacgc
    42541 ttggaccaac tgcaactgcg tttgaaacaa agtttgcgaa ctcggatttc tgataacaaa
    42601 caattagttc aagcaagaac tcatcaatta gtacaattat cacctgttac caaaatccaa
    42661 cgctatcaag accgtttagg acagttggac aagctcttag gtagccaaat ggcgttagtt
    42721 tatgacgcca aggttgctga ggccaagcga ctttcggaag ctttgctcat gttggatact
    42781 agccgaatcg tggcgcgtgg ttatgctatt gtcaaaaaag aagagtccgt tgtagattcg
    42841 gttgagagtt tgaagaaaaa agaccaagta acgcttttga tgcgagatgg tcaagtagaa
    42901 ttagaggtta aagatgtcaa aacaaaagaa atttgaggaa aatctagcag aactggaaac
    42961 cattgtccaa agtttggaaa atggtgaaat tgctctggaa gatgcgatta ctgcctttca
    43021 aaagggcatg gtcttgtcaa aagagctcca agctacgctg gacaaggctg aaaagacctt
    43081 ggtcaaggtc atgcaagaag acggaacaga aagtgatttt gaatgaaaaa gcaagaaaaa
    43141 ttagctcttg tcgagtcggc tttggaagat ttttatggag accagcagtt tgcctctagt
    43201 ttacgggagt ctgttctcta ttctattcat gctggtggca agcgtattcg gccttttctc
    43261 ttgttagaag ttctggaatc cttgcaggtt accatcaaac ctgctcacgc gcaggtagct
    43321 actgccttgg agatgattca tacagggagc ttgattcacg atgaccttcc tgctatggat
    43381 gatgacgatt atcgaagagg gcggttaacc aatcacaaga aattcggtga agctatggcc
    43441 attttggctg gagatgcctt attcttagac ccatatgcct tgattgcgca ggcagatttg
    43501 ccaagtcaga tcaaggtgga cttgattgcc aacttatccc ttgcttcagg tagtctgggt
    43561 atggtggcag ggcaagtttt ggatatggag ggcgaacacc agcacttgtc tctggaagaa
    43621 cttcagacta ttcatgccaa taagactggg aagttactag cctatccctt ccaagcggca
    43681 gctattatag ctgaattgtc acctgaaatg caggtgaagc tgaaaactgt gggtgaattg
    43741 attggacttg cttttcaagt cagagatgat gtactggatg tgacagctag ttttgaggaa
    43801 atcggcaaga cacctcaaaa ggatctgcag gcagaaaaat caacctatcc tgccttgttg
    43861 ggcttggaag agtccattgc cttttgtaac caaaccctgg atcaagctaa tgaaaaatta
    43921 gaagaaattg cccagcagct tccctttgaa acagaatcga ttgtaagtgt agtagaaagt
    43981 ttgagaatca atggctaagg aaagagtgga tgtactagct tataaacagg ggttgtttga
    44041 aacgagagag caggccaagc gaggtgtgat ggctggtcta gtcgtagcag tccttaatgg
    44101 agaacggttt gacaagccag gagagaaaat tccagatgac accgaattaa aactcaaggg
    44161 ggagaaactc aagtatgtca gccgtggtgg tttgaaactg gaaaaggcct tgcaggtctt
    44221 tgatttgtcg gtggatggcg cgactacgat tgatatcggg gcctctactg gaggttttac
    44281 cgatgtcatg ctacagaata gtgccaagtt ggtctttgca gtcgatgttg gtaccaatca
    44341 gttggcttgg aaattacgcc aagacccacg agttgtcagc atggagcagt tcaattttcg
    44401 ctatgctgaa aagactgatt tcgagcagga gccgagcttt gccagtattg atgtgagttt
    44461 catttccctt agtctgattt tgccagcctt gcacagtgtc ttggctgatc aaggtcaggt
    44521 ggtagcactt gtcaaacctc agtttgaggc aggacgtgag cagattggga aaaatggaat
    44581 tattcgagat gctaagattc atcagaatgt ccttgaatct gtaacagcta tggcagtaga
    44641 ggcaggtttt tcagtccttg gcttggactt ttctcccatc caaggtggac atggaaatat
    44701 tgaattttta gcgtatttga aaaaagaaaa gtcagcaagc aatcagattc ttgctgagat
    44761 taaagaagca gtagagaggg cgcatagtca atttaaaaat gaataaaaaa gaaagacttg
    44821 aaaaaattag aagattggtg acagattatc aaatcggcac gcaagaagaa attgtagaac
    44881 atttgaaaga agcaggtatc actgccactc aggcgacggt atcccgagat atcaaagagt
    44941 taggtattgt caaaattcct ttgagagaca acacctatgt ctacgaattg ccaaaatcaa
    45001 tcgtaaaaag tctgcaactg gctgaagaca atatcgaatc ggctgaattg atggataaga
    45061 tgatcaatct ccaagttatt ccaggaaata cggcttttgt aaaagctcag ttaatcgaga
    45121 cttttgcaga caagattttt agctgtttga ctgatgatag ctcgatttta gtcattgcca
    45181 gaagtggaag tctagcagag gaaatctttg aacaagtaaa aaattggtag gtctatatgt
    45241 tacttgaaat ttcgataaaa aactttgcca ttattgaggc tatttccctc aattttgaaa
    45301 aggggatgac tgtcctgact ggtgaaacgg gtgcagggaa gtcgattatc attgatgcca
    45361 tgaatatgat gttgggagct cgtgcgacga cagatgttat tcgtcatggt gcaccaaagg
    45421 cagagattga ggggcttttc tcagttgaga atagtcgtct tttacaggaa atttttgatg
    45481 agcaaggttt agaattaggt gatgaaatta tcatccgtcg ggaaatcttg caaaatggtc
    45541 gtagtatcag ccgtgtaaat ggtcagatgg ttaatctgtc tgttttgcga actattgggc
    45601 aacatcttgt agatattcat ggtcagcatg accatgagga gttaatgcgt ccccaactgc
    45661 atatccagat gttggatgaa tttggtgatg ccgctttttg ggacttgaaa gaaacctatc
    45721 aaacgagttt tgatgcctat cggaaaatgc gcaagcaggt tctggaagtc aagaaaaacc
    45781 aacaggaaca caaggcacgt atcgaaatgt tggaatttca aatggcagag attgaggcag
    45841 caaacttgca ggctggagaa gacttggatc tcaatcaaga gcgagataaa ctcctcaacc
    45901 acaaaaatat tgcggataca ctgaccaatg cctacagtat gttggacaat gaagattttt
    45961 caagtctggc caatgttcgt tcagccatga atgacatgga aagtgtcgaa gagtatgacc
    46021 ctgaataccg tgaaatttca agctctctgt ctgagaccta ctatgtttta gaagacatta
    46081 gcaaacgttt ggaagctatc attgaggacc ttgattttga tggcaatcgc ctcatgcagg
    46141 ttgagaatcg tttggacctc cttcatacta ttactcgtaa gtatggtggg actgttgatg
    46201 atgttttgct ttattttgcc aagattacgg aagaatacaa tctcttgaca ggcaataatc
    46261 tttcgtctga ggacatggaa gcagagctta agaagttgga agtcaatctt gtcaatttgg
    46321 caggtcaact tgcttctgct cgtcataatt tggctcagca actcgaagct gagattaaac
    46381 aagaactgca agatctttat atggaaaaag cccagtttca ggttcgtttt agtaagggaa
    46441 aattcagtcg tgagggaaat aaaatggttg agttttatat ttcaaccaac cctggagaag
    46501 actttaaacc cttggttaag gttgcttctg gaggggaatt atctcgtctc atgttagcca
    46561 ttaagtctgc cttttcacgt aaagaaggca agactagcat tgtctttgat gaggtggata
    46621 cgggagtttc aggtcgtgtt gctcaagcta ttgctcagaa aattcataaa attggtcagc
    46681 atggtcaggt tttggctatc tcccatttgc cacaagtaat tgcgattgca gattatcaat
    46741 tctttattga gaagattagt aatgaccatt caacggtttc gactgttcgt ctcttgacgg
    46801 tcgaagagcg agtggaggaa gttgccaaga tgttggcagg tgatgatgtg acagaagcag
    46861 ccctgacgca agcaagagaa ttgttgagaa acagggagaa ataagatgac agattattat
    46921 gtaattggag atgttcacgg aaaagctggg atgctggaag accttctcaa aacctgggat
    46981 ggtcagcccc agttgctctt tctaggtgat ttgattgaca gaggtgagga tagtcaccgt
    47041 gttcttgaaa tggtcaagga cttggtggac aatcaagggg ctatctgttt gtccggaaac
    47101 cacgagtata tgtttttgac ttggctagat gacccagaag aaagttatga ccattatagt
    47161 cgcaatggtg gagatacaac cattaactct atcctaggtc gtcccttgga tgcaccagtt
    47221 gatggagtag aagatgccaa gcgggttgcc gctgaagcgg cagacttggt cgaattcatt
    47281 cgtcaaatgc catttgtagt agagacagac aagtatatct ttgttcacgc aggtattgat
    47341 ttgaccttgg acgactggca tgaaacaaca gattataaaa aagtatggct tagaaaacca
    47401 ttccacggag ctgaaaatca tactggaaaa accattgtct tcggtcatac accggtctat
    47461 ggtttattac agcaagaacg cggtacatct gagctttgga ctacagaaga tggcaagatt
    47521 ggaatggatg gaggagctgt ttatggtggt gtccttcacg ggattgtctt tacagaccaa
    47581 ggaatgacag aacaccactt tatcgaaaat gacggctttg tcgctgaaga ttagtactcc
    47641 tagcagggta tggtcttgtc aaaatatcaa aaacaattta taataaatag ataccctgaa
    47701 aggaagagaa tcatgaactt agaagaattg aaaaaacgac aggagaagat ccgtaacttc
    47761 tctattatcg cccatattga ccacggaaaa tcaactctag cagaccgcat tttggaaaaa
    47821 acagagacgg tttcaagtcg tgaaatgcag gcccagcttt tggatagcat ggagctagag
    47881 cgggaacgtg gaattactat taagttgaat gccatcgagt tgaattacac tgcaaaagat
    47941 ggggaaactt atattttcca cttgattgac acaccagggc acgttgactt tacctatgaa
    48001 gtttcacgtt cgctagctgc ctgtgagggt gctattttgg tggtcgatgc ggctcaagga
    48061 attgaggctc aaactcttgc caacgtttat ctggctttgg ataatgattt ggaaatcatg
    48121 cctatcatta ataaaattga cctgccggct gcagatccgg agcgcgtgcg tacagagatt
    48181 gaagatgtga ttggtttgga tgccagtgaa gcagttttgg cttctgccaa ggctggtatt
    48241 gggattgaag aaatcctcga gcaaattgta gaaaaagtac cagcaccaac gggtgatgtg
    48301 acggcgccac ttaaggcctt gattttcgac tctgtttacg atgcttaccg tggggttatc
    48361 ctccaagtgc gtgtcatgga cggagtggtc aaacctggtg ataagattca gctcatgagc
    48421 aatagtaaga cctttgatgt ggccgaagtc ggtattttta caccaaaagc ggttggtcgt
    48481 gatttccttg cgactggtga tgttggttac attgcggcgt ctatcaagac ggttcaggat
    48541 actcgtgtgg gtgataccgt taccttggca accaatcctg cggcagaacc attacatggt
    48601 tataagcaga tgaatcctat ggtctttgcg ggtctctacc caatcgaatc aaacaagtac
    48661 aatgacctgc gtgaagcgct tgaaaaattg caactgaatg atgctagtct tcagtttgaa
    48721 ccagaaacat ctcaggcact tggatttggt ttccgttgtg gatttcttgg acttctccat
    48781 atggatgtta tccaggaacg tttagagcgt gagttcaata ttgacctcat catgacagct
    48841 ccgtctgtta tttacaaagt taatttgacc gacggtgagt ctatggatgt gtctaaccca
    48901 tctgagtttc cagacccaac taagattgcg accattgaag agccttatgt caaggcgcaa
    48961 atcatggtac cacaggagtt cgtcggagca gtaatggagc tagctcagcg taagcgtggg
    49021 gactttgtga ctatggacta tattgatgat aaccgtgtca atgttatcta tcaaattcct
    49081 cttgctgaaa ttgtctttga cttctttgat aaacttaagt cttcgacacg tggttatgca
    49141 agctttgact acgaattgtc agaatatcgc ccatctaagc tggtgaaaat ggatattctt
    49201 ctcaatggag ataaggtgga tgccctcagc tttatcgttc acaaggactt tgcctacgaa
    49261 cgtgggaaac tcatcgttga taaactcaag aaaatcatcc ctcgccaaca atttgaagtt
    49321 ccaatccaag cggctattgg acacaagatt gtcgctcgta ctgatatcaa ggcccttcgt
    49381 aagaacgtac ttgctaaatg ttatggtggt gacgtttctc gtaagcgtaa actccttgaa
    49441 aaacaaaaag ctggtaagaa acgcatgaaa tccatcggat cagttgaagt tccgcaagaa
    49501 gccttcctca gcgtcttgag tatggatgaa gaataagtta tcagaaatgc ctttccttgt
    49561 tcacaggaaa tttataagaa tcaatagtaa agcaggctta gatggtctgc ttttttagtt
    49621 tttatactct tcgaaaatct cttcaaacca cgtcagcgtc gccttaccgt atgtatggtt
    49681 actgacttcg tcagtttcat ctacaacctc aaaaccatgt tttgagctga cttcgtcagt
    49741 ttcatctaca acctcaaaac tgtgttttga acaacctgcg gctagcttcc tagtttgctc
    49801 tttgattttc attgagtatt agaacagaaa aaatgcttgg agtatttgtt tgtgtgttta
    49861 cttttatata acaaactata aacacaacaa aaatataaaa aaagagacaa aaaagaacag
    49921 aaagtaatta acaacgattt catatagtgt tatacttata gcataaagtt aatggaaaga
    49981 agggaaaacc ttatggtatt agattatttc tttgacaaaa accttgtgtt ttgcttagaa
    50041 gcggataatc aagaataact ctttgatcag gtagcaagct tgttggagga acgagaaatt
    50101 gt
//
LOCUS       DAVAZT010000006        48675 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVAZT010000006 DAVAZT010000000
VERSION     DAVAZT010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48675
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.006"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            263..1321
                     /locus_tag="VQT45_000311"
     CDS             263..1321
                     /locus_tag="VQT45_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2358707.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREIALLLATIIVYFFTHRILPLSVFTFIFSYILLFAQ
                     SYLGGNTVWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNLTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALGDLSKQYLNRNISELQDGSFDGGIQDAVASKQIVVINEFIACLNSRCMPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            1636..2610
                     /locus_tag="VQT45_000312"
     CDS             1636..2610
                     /locus_tag="VQT45_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2358708.1"
                     /translation="MKNKRYFFDTILMILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSTK"
     gene            2990..3364
                     /locus_tag="VQT45_000313"
     CDS             2990..3364
                     /locus_tag="VQT45_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HET2358709.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGFSIPRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            3572..4474
                     /locus_tag="VQT45_000314"
     CDS             3572..4474
                     /locus_tag="VQT45_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2358710.1"
                     /translation="MIRKLIVFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEGLIKIFPFIFIRRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWQKEDSFESNLHKILMDKIQKSELSYSDLMSLLLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            4530..4769
                     /locus_tag="VQT45_000315"
     CDS             4530..4769
                     /locus_tag="VQT45_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HET2358711.1"
                     /translation="MELVLPNNYVVIDEEVMMYLDGGAYLSKRACQGICAAAGVLATA
                     AGKIAYCIGYGVLNRGCDINENPYPWDGFISATVR"
     gene            4766..5494
                     /locus_tag="VQT45_000316"
     CDS             4766..5494
                     /locus_tag="VQT45_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2358712.1"
                     /translation="MSNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLVINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IRKDFDIKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGKVDNHVLTLI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEYELFKNSK"
     gene            6629..6868
                     /locus_tag="VQT45_000317"
     CDS             6629..6868
                     /locus_tag="VQT45_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2358713.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQDGVFILEDFRNILCTMM"
     gene            7418..9136
                     /gene="pspA"
                     /locus_tag="VQT45_000318"
     CDS             7418..9136
                     /gene="pspA"
                     /locus_tag="VQT45_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein A"
                     /protein_id="HET2358714.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTFVRAEEAPVASQSKAEK
                     DYDAAVKKYEAAKKEYEDGKAAQKKYEDDQKKTEEKAEEERKASEEEQAANLKYQQEL
                     VKYIRENDPTKKAEAKKAMDEAEKEYKKKQTEFAEVRAKVIPSAEELKKTRQKAEEAK
                     AKEAELTKKVEEAEKKVTEAKQKVDAEHAEEVAPQAKIAELEHEVQKLEKALKEIDES
                     DSEDYVKEGLRAPLQFELDVKQAKLSKLEELSDKIDELDAEIAKLEKDVEDFKNSDGE
                     QAGQYLAAAEEDLVAKKAELEKTEADLKKAVNEPEKPAEETPAPAPKPEQPAEQPKPA
                     PAPQPEKPAEEPENPAPAPQPEKSADQQAEGDYARRSEEEYNRLTQQQPPKAEKPAPA
                     PQPGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNANGAMATGWLQYNGSWYYLNAN
                     GAMATGWLQYNDSWYYLNANGAMATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLN
                     ANGSMATGWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGLGALAVNTTVDGYKVN
                     ANGEWV"
     gene            9537..10658
                     /gene="mnmA"
                     /locus_tag="VQT45_000319"
     CDS             9537..10658
                     /gene="mnmA"
                     /locus_tag="VQT45_000319"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HET2358715.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRRLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            10799..11254
                     /locus_tag="VQT45_000320"
     CDS             10799..11254
                     /locus_tag="VQT45_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2358716.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELDVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLQNIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            11264..13177
                     /gene="mnmG"
                     /locus_tag="VQT45_000321"
     CDS             11264..13177
                     /gene="mnmG"
                     /locus_tag="VQT45_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HET2358717.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            13366..13455
                     /locus_tag="VQT45_000322"
                     /pseudo
     CDS             13366..13455
                     /locus_tag="VQT45_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(13601..15280)
                     /locus_tag="VQT45_000323"
     CDS             complement(13601..15280)
                     /locus_tag="VQT45_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET2358718.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLRLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(15282..15515)
                     /locus_tag="VQT45_000324"
     CDS             complement(15282..15515)
                     /locus_tag="VQT45_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HET2358719.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            15897..16118
                     /locus_tag="VQT45_000325"
     CDS             15897..16118
                     /locus_tag="VQT45_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2358720.1"
                     /translation="MTNQVLEENYLCDSLLAFSPPRDLCRLVCILLWIKCLDALLMLG
                     FFVWGCRDSRFTTRKFHPIYQDEVVFAFF"
     gene            complement(16331..16483)
                     /gene="cibB"
                     /locus_tag="VQT45_000326"
     CDS             complement(16331..16483)
                     /gene="cibB"
                     /locus_tag="VQT45_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HET2358721.1"
                     /translation="MMKDLNNCREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(16485..16670)
                     /gene="cibA"
                     /locus_tag="VQT45_000327"
     CDS             complement(16485..16670)
                     /gene="cibA"
                     /locus_tag="VQT45_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HET2358722.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            16848..17531
                     /gene="tsaB"
                     /locus_tag="VQT45_000328"
     CDS             16848..17531
                     /gene="tsaB"
                     /locus_tag="VQT45_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HET2358723.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMESLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLTHTLNIELVGMSSLLALVPY
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMPEAHLSFEEVLEKVKGASQVTFVGEVGPF
                     VEQIQEHLPRTNYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            17528..17965
                     /gene="rimI"
                     /locus_tag="VQT45_000329"
     CDS             17528..17965
                     /gene="rimI"
                     /locus_tag="VQT45_000329"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HET2358724.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            17955..18965
                     /gene="tsaD"
                     /locus_tag="VQT45_000330"
     CDS             17955..18965
                     /gene="tsaD"
                     /locus_tag="VQT45_000330"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HET2358725.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLYHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(19011..20311)
                     /locus_tag="VQT45_000331"
                     /pseudo
     CDS             complement(19011..20311)
                     /locus_tag="VQT45_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(20587..20938)
                     /locus_tag="VQT45_000332"
                     /pseudo
     CDS             complement(20587..20938)
                     /locus_tag="VQT45_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(21045..21337)
                     /locus_tag="VQT45_000333"
                     /pseudo
     CDS             complement(21045..21337)
                     /locus_tag="VQT45_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            21580..22786
                     /locus_tag="VQT45_000334"
                     /pseudo
     CDS             21580..22786
                     /locus_tag="VQT45_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            22779..23427
                     /locus_tag="VQT45_000335"
                     /pseudo
     CDS             22779..23427
                     /locus_tag="VQT45_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            23437..25053
                     /locus_tag="VQT45_000336"
     CDS             23437..25053
                     /locus_tag="VQT45_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2358726.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLSGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            25073..25917
                     /locus_tag="VQT45_000337"
                     /pseudo
     CDS             25073..25917
                     /locus_tag="VQT45_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813546.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            25985..27486
                     /locus_tag="VQT45_000338"
                     /pseudo
     CDS             25985..27486
                     /locus_tag="VQT45_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819023.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase"
     gene            27498..28247
                     /locus_tag="VQT45_000339"
     CDS             27498..28247
                     /locus_tag="VQT45_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HET2358727.1"
                     /translation="MSDNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSKLKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            28260..29432
                     /locus_tag="VQT45_000340"
     CDS             28260..29432
                     /locus_tag="VQT45_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET2358728.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGTLP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     SFAERRSLNAEVVIKGVCLDPRIGNFYNNPSFGFGGYCLPKDTRQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFIKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
     gene            29827..30690
                     /locus_tag="VQT45_000341"
     CDS             29827..30690
                     /locus_tag="VQT45_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET2358729.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRIGRRVVDCFSHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKNALHSLDKSYPLTEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRWYMKSGYLNIISELMERKLFSYIPIFE
                     AELERMLRPYDVFEKVLWQFLKKMQIFLQTKGSNQKEIEHFIQSLQVLENPQLTALFE
                     LRLQQYKELID"
     gene            30976..31209
                     /locus_tag="VQT45_000342"
     CDS             30976..31209
                     /locus_tag="VQT45_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2358730.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            31231..31908
                     /locus_tag="VQT45_000343"
     CDS             31231..31908
                     /locus_tag="VQT45_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2358731.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATSLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVKRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            31920..32585
                     /locus_tag="VQT45_000344"
     CDS             31920..32585
                     /locus_tag="VQT45_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2358732.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAILFGVSHISNHGWVLTDFFVYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            32657..33883
                     /locus_tag="VQT45_000345"
     CDS             32657..33883
                     /locus_tag="VQT45_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2358733.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICLLNLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPISTLFLRNQPFLNLQTGQSLALLATLEL
                     SALILGSLMSGYLQHTISIKIALYASLLLQLLLLVGFATAHFGLILIFSFLDAFFAGI
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALGTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(34234..34311)
                     /locus_tag="VQT45_000346"
                     /pseudo
     CDS             complement(34234..34311)
                     /locus_tag="VQT45_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            34382..35038
                     /locus_tag="VQT45_000347"
     CDS             34382..35038
                     /locus_tag="VQT45_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HET2358734.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            35028..35351
                     /locus_tag="VQT45_000348"
     CDS             35028..35351
                     /locus_tag="VQT45_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HET2358735.1"
                     /translation="MVSKYLLLAVIFSDLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAV
                     LRLVF"
     gene            35455..36285
                     /locus_tag="VQT45_000349"
     CDS             35455..36285
                     /locus_tag="VQT45_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2358736.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NSSPKPFNYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYQMAV
                     NNISYTKERAEKYLYAAPTVKDPNVLVVKKDDSSIKSLDDVGGKSTEVVQGTTSAKQL
                     EDYNKQHSDNPTILNYTKANLQQIMGHLSDGQFDYKISDKITVETVIKNQGLDNLKVI
                     DLPSDQQPYVYPLLAKGQDELKTFVDKRIQELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            36326..36403
                     /locus_tag="VQT45_000350"
                     /pseudo
     CDS             36326..36403
                     /locus_tag="VQT45_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC protein"
     gene            36507..37337
                     /locus_tag="VQT45_000351"
     CDS             36507..37337
                     /locus_tag="VQT45_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2358737.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NGSPKPFIYEENGELTGYEIEVVRAIFKDSDKYNVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            37491..38345
                     /locus_tag="VQT45_000352"
     CDS             37491..38345
                     /locus_tag="VQT45_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HET2358738.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            38445..39818
                     /locus_tag="VQT45_000353"
     CDS             38445..39818
                     /locus_tag="VQT45_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HET2358739.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            39811..40872
                     /locus_tag="VQT45_000354"
     CDS             39811..40872
                     /locus_tag="VQT45_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HET2358740.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            40874..41566
                     /locus_tag="VQT45_000355"
     CDS             40874..41566
                     /locus_tag="VQT45_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2358741.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(41596..42165)
                     /locus_tag="VQT45_000356"
     CDS             complement(41596..42165)
                     /locus_tag="VQT45_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET2358742.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADGVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            42300..42914
                     /locus_tag="VQT45_000357"
     CDS             42300..42914
                     /locus_tag="VQT45_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET2358743.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            42916..44562
                     /locus_tag="VQT45_000358"
     CDS             42916..44562
                     /locus_tag="VQT45_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2358744.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDR
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKYFEHRASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            44574..45860
                     /locus_tag="VQT45_000359"
     CDS             44574..45860
                     /locus_tag="VQT45_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2358745.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLSSFFGQYRMNENVVSVLEVIGCD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            45921..46454
                     /locus_tag="VQT45_000360"
     CDS             45921..46454
                     /locus_tag="VQT45_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2358746.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRTAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKASAEEEETEELA"
     gene            46532..47002
                     /gene="nrdI"
                     /locus_tag="VQT45_000361"
     CDS             46532..47002
                     /gene="nrdI"
                     /locus_tag="VQT45_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HET2358747.1"
                     /translation="MKIISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(47295..48557)
                     /locus_tag="VQT45_000362"
     CDS             complement(47295..48557)
                     /locus_tag="VQT45_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HET2358748.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFSGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
BASE COUNT        15140 a         8125 c        10220 g        15190 t
ORIGIN      
        1 aaatctaata aattctatta ttatagctct tggtatgata ttggcattaa ttttggtatt
       61 atcaagagtg tatagaaaat atttttatag agacgatgat gactaaagtt tttatcaata
      121 atttgggctc cttgtcaact gtagtggatt gaagaaaagc taacgtctgg ggaagggttt
      181 aaagctttgc tttatcaaat attgacttac agagttgctc tattgtattg atgtattctt
      241 agtaaataat atggtgtttt gaatgaaaga tgatcagaaa tatttattag cgggacttta
      301 ttcgcttcta gttgcaatat tttattttcc attgattgag tccaagggga tttttgtaag
      361 tatattgatg gcggttttac ttttatattt aatatacttc attgcaacag tcattcatat
      421 tgtgataatt aagtttataa gaaaaaaatc ttttaagtat ttggttctat atccatttac
      481 ttatgatggg agctggagat ttcaacctat aaacttactc tactttccag aaatggtgag
      541 agatgtcatt ccgattaatt tagttcaaga atattgccaa ggacaacctt acggactgtt
      601 aaaaaagatg ctgaaaagaa ttcgattgtc acgagagata gctttactcc tggctaccat
      661 tatcgtctat ttttttacgc atagaattct acctctttca gtatttacgt tcatattttc
      721 ttacatattg ctatttgcac aatcttattt gggtggtaat accgtttgga ttggaaatag
      781 aagattaata atagatgatg aatttgaaaa aatcttgctt tcaaaaagtt atataaaaga
      841 aatatcatct gcacgatact cggaatactt gacatgtgaa tacaaaaacc ttacaccaat
      901 catattgtta gctatttttg aaaatttgct tgactcctac ttgcttcaga atcagagtga
      961 ggttgactta gatatttttt ataaagtttt acctttgctt tataaagaaa aatatactat
     1021 gggattcaat tactttgtaa gtttaaatta tttactatat aaggttggat ttttgggaat
     1081 catttacgat aatgaagcat taggagattt gtcaaaacaa tatttaaaca gaaatatttc
     1141 ggaattacaa gatggttctt tcgatggcgg tatacaagat gctgttgcct ctaaacaaat
     1201 agtagttata aatgaattta tagcttgttt aaattccaga tgcatgccat cccaatatga
     1261 tagatttttt tataaagata gaccttatat tttttccaga aagagtccta ttaaggggtg
     1321 aaaatttgtt acatttggat taacaagtgt cctagggatt agaaataact ctagtatagc
     1381 tagatatttt tgagtaacta gaaatatcat taggctaccc atatgattgc cagaaaagat
     1441 ggctgatgaa tcttatttat actgttgcag taggcattgt ctaggataaa taagctatct
     1501 tgatggggga aattggaata attttagtag aaacattaaa ggattatgga caagtagcgc
     1561 aggattaggt gatgcaatgt gctaagttgg cttggtgtta gcagtagtat tatttaacaa
     1621 tggaaagtag actaaatgaa aaataagcgt tatttttttg acacaatttt aatgatttta
     1681 ctgcttataa gcacgatatt ttgtgtcagc ccagtattta taaaattgga catcttagga
     1741 accccctctc atgccatctt aacctttgta ttggcgatac cgttattcta tattttgtct
     1801 caatgcttac atactttgct attactagtt tcctcaatct tttgtaaatt aagaccaatt
     1861 tatttttatt ttatatttgt gatcattata ggagctagga aatactatcg aattctcttt
     1921 caccaactaa tgggatttag tccaggaata gcagtgtttt ataaggagag tcaaacaact
     1981 aagaatctgt ttaaatttta ctacttcttg tactttacaa cactaatttc atactatttt
     2041 ttctttactt ttgtgtatga caaaccgttg cttttgcctc ttattccatt ttctattatc
     2101 atagcattag tacaaaaact ttatagaatt gagaatcaac aattatttct gttaaaatca
     2161 aaggtactaa caatactgga atctaagaag aattgtgagt ttaatcttca ggattatcat
     2221 gaaatttgga aattgcaatc aaaatctgag ttgccatgcg tggctttatc ttatatcagt
     2281 ttgatcaagc catatctttc agagagcgtg cgtgaacaaa ttgatttatt agaagttaag
     2341 cgatttaaaa aaataaatca tccaatatca ctttatggta tgttggatgt tataaaatta
     2401 aatctatatt tacggcatta taatgaaaaa aataaatatg aatcaatgtt aaagaaaatt
     2461 ttagaggtaa gaccagactt tgttttaatc gagcagaata ttgatgatag tttaaatagc
     2521 tcgcaaccat tatctttatc tttagccatt tcagaaatcc aacttttgct tgaagtgtat
     2581 atggggatca aacatgtttc aaccaagtga taaaaccaga ataatatttg ccattatagg
     2641 ggcaagttgc atattagtca gtatgtatct tattccactt attaaaactg agaataaatt
     2701 ttgggaaata cttttattta tattaggtgt attgctaatt ggaattgcgt tactaagtca
     2761 aaaaaaataa attttgaaat agtattagtg agttcgcaat catttattgc tagtggttta
     2821 gaactgttaa gtttcaaaca ataattgatt ttaaacctta ggtaacctat aaaaacaaat
     2881 aaggtagaga aaggatatct tatctaggta gctaagtgat aaaaacacag tcgtctatca
     2941 cttgttagga aactatccta actatgctta ataaaaaagg agaaaataaa tggaactcgt
     3001 attaccaaat aattatgttg ttcttgagca agaagagatg atgtatcttg atgggggatt
     3061 ttctattccg agatggcctg ttgcaacagc cattaatata gcttttaatg gtgttttagg
     3121 tggaggagca atcagtctag ttagaaatta tattcgtaat tatggtttgc ggcgagttac
     3181 aagcgcaatt gctggagcag ctgcaagata tgttggggta cgagttgcaa atagagtggc
     3241 aggatttgca ctgtctgcta ttaatggatt tgcagcttgg atgtcaattg gcgatgctat
     3301 tacaacaatc tgggccaaca atgatgtaaa taggagagac ccaaatttaa acgccttgtg
     3361 gtaactagat atgggtatta aaatggaaaa aatttttgtt attatttttt ttgtatgtct
     3421 atttatatca tccataactt ttttagccta tgattttgtt agcgaagaaa taaaaaagtt
     3481 gattatttgg attaatgtcg tttttttgat tttaatcata gcaatgatga tttatccaaa
     3541 attaagaaaa tgataaggac actgtaaaat tatgatacgt aaactaattg ttttcttact
     3601 aatgctccct ctttttgtct tgtggctaga gttgcatgtc ctagtgaata acttactatt
     3661 gaatctagaa tctccccttg attttgtgat tagtatgagt cttgctttct gtagtttgat
     3721 tttatcaaaa atagttttag acatactata cgcattgaaa gatttataca agaaagaagg
     3781 tcttattaag atttttccct ttatttttat aagaaggaaa aaagtgaatg tgagattctc
     3841 gccctatttt tcattccatc gtaaaagttt gtcgcctgat gatttaagat ctaggattat
     3901 atggagtttt attcttgaaa ttgctattat cctagtattt attttaaaaa ttccttttgc
     3961 aatcatcatg cttactacaa tatttttctg gactataatg gatatcaatc atctcgtttt
     4021 taataagacg gaatttcttt ttaatcaaaa caaatggcaa aaagaagatt catttgaaag
     4081 taatttgcat aagatattga tggacaaaat acaaaaatca gaattaagct attctgactt
     4141 aatgtccctt cttctctatg atgcgatgaa ccaatccacc tttttaacgg atagtgaact
     4201 ttttgaggat attttgaaaa aaatcgaaga ttctcataac acccttctgt gtacaggtct
     4261 tgtcgagtta ctgctgtatg agatttctat tagtaacaat aacaactggc aagaaaaggt
     4321 tgataaaatt agaatacagc tcatcagaat caatcaatta gattttttct attatacaag
     4381 ttggttaagg caaaattttg atttctgtat gaatagagag tatcataaaa tgaaatctcg
     4441 gaaattatta ctgagtaata aaaagatagt ttaagttcgt cctatttgta aaacaaatga
     4501 aacaatttca actaaggagg agaaaacaaa tggaacttgt attaccaaat aattatgttg
     4561 tgattgatga agaagtaatg atgtatcttg atgggggagc ttatttaagc aagcgtgctt
     4621 gtcaaggaat ttgcgcagca gcaggtgtat tggctacagc agcagggaaa atagcttact
     4681 gtattggata tggtgttctt aatagaggtt gtgatattaa cgagaaccct tatccttggg
     4741 atggattcat atctgcaaca gtaagatgag taatgtagat aagattcgaa aaatacacat
     4801 catcgtgtgt tgggtgtata tatttttatc attcagggcg attataaatg atacggagta
     4861 ttttttgctt atttttttag cttttatcta ctcaatagta tcactacctc tatattctgt
     4921 gaaaaataaa atagtatcta tctgtctagt tataaattcg attctgttaa tgagtttccc
     4981 cattttaatc aataagtttt tcccagaaag ttttttgact tataccgtat taataagtgt
     5041 ttttatccta gagttagcaa tctttcattt aattaggaaa gattttgata ttaaattgac
     5101 taacgaatat aagaaaatta gtcagtttag aagcaaggtg tctcaatctc cttggataaa
     5161 atatttagag atttctagtt ttatattaac tatatttcca tctattcttt atggtaaagt
     5221 tgataatcat gtactgactc ttatcttttt gataaaaatt tgtgtagata ctacgataaa
     5281 atttttattc atcagattat ttgacacaag tactttaatg aagaggagaa tattttttct
     5341 tttcgcattg gatgttatag cttacttatt tttaggatat cttttagtga ttcaaaaagc
     5401 aggctatttg ttttcggttt tacttctttt ttctaatttt tcagttccat ttatcaaaga
     5461 aaaggaatac gaattattta aaaatagcaa gtaatagaaa tatggattaa atcttagaac
     5521 ggcttaaaat cagatatgat aaagggaaat agtcttatct aggtaactaa gtgctacaaa
     5581 cacaatcgag gatcacttgt taggattaca ttttaatcat gcttaataag aatggagaat
     5641 tcctatgggg attgtattac tctgaagttt cgaatacctt agttctcgtg attttgagct
     5701 attctagctt tagaatcctt cagaacgtaa aattttaagc agtcaaagac ttagaatagc
     5761 ctgaaaacat ttattttata gcaattctag gcttagaatt gctcatatat atgtatttga
     5821 gctgctcgat agttaggaca gctctattct gagaaatctg agctatcaat gcttcagaat
     5881 agtatttcgc caatggtttt tattgaagag gtgattgtgt tatgatagtc taaaataaaa
     5941 ttgatttaat agagtaaatg gagaatcgtt acatgaaaca tttttttgca ggaattggtg
     6001 agataaaact tgttggctac ttattgtata tatgtgtagg actagcccct ctttttcata
     6061 tatatgtcat aggttcggaa ctgagttttg tgaaaatagt gttatctatt ttgggagtta
     6121 tatttgtaag tatgttaact attgctcgaa tttatcggac ttttctataa agaatagttt
     6181 ggacttaaac tgtatctaaa aacagaggtt ggtcgattat cagcctcttt cttgtcgttg
     6241 aaaagagtga gatatattga cttttgaaaa aaagatgtca taattgagtt gggataaacc
     6301 taaaagtaat atagtagatt gaatctggaa tagtccgtta tgactgttaa aatatttcta
     6361 gaaattaatt tgactttcct aatcgatttg ttcacatctt gtttcaatct actatacttt
     6421 ctcgttaaac cgttcggcaa ttcatggtga catggacaca tagtagtaag cacactatgt
     6481 ggcttggcag agctaaaaac tgttcccttg cgataagcct aataagcaca acatagggag
     6541 ttagagaagc cgactctaat caaccacttt gggcaatagt gagaactgcc ccgtgctttt
     6601 ttattttgag aaaatatgga gtttgtcgtt gaaattactt gattgtattt tggactatca
     6661 agaaagattc aatggaaaaa catgtcaagt atcaacgaat tataagtatt tagagatttt
     6721 caaagtgaat ttttgtttga ctgatttaca tcatttattt gacttataca aaatcacacg
     6781 agattatgct agtcaaacaa aacctgctat tcaagatggt gtttttattt tagaagattt
     6841 tagaaatatc ctatgtacaa tgatgtaatc gaaaggatat ctttatgtga gtttatcggc
     6901 gatatcttct atatctaagc tagcaagttg ttgcatcgta gctaaggatt tatctaaaaa
     6961 tactatgaaa ttggacgtca tattttttga ggataaaaat aaaagatccg cagttttagg
     7021 tttacgaaga gacaaaagcg gagtatttaa accagttact ctacatttta caagcgctaa
     7081 gaaatatgct aaagttcgta aaacagatgt gaaagaaatg aaatggctat aaagattgtc
     7141 cgcaggctta agcttgcgtt ttttgttgtt taacgaaatt aaaaaacaag ctctctcatc
     7201 ggaaatgttt ttataggaat gaaggaagat gatgctatgt ttaaaaagag aatcgaaaag
     7261 ggcaaaagta gtgtctttat ctttttggag tagaagctta tgatatagaa atttgtaata
     7321 aaaatgtaat ataaaacatt tgacaaatat ttacgggggg agtatactta atataagtat
     7381 agtctaaaaa tgactatcag aaaagaggta aatttagatg aataagaaaa aaatgatttt
     7441 aacaagtcta gccagcgtcg ctatcttagg ggctggtttt gttacgtctc aacctacttt
     7501 tgtaagagca gaagaagctc ccgtagctag tcagtctaaa gctgagaaag actatgatgc
     7561 agcagtgaaa aaatatgaag ctgctaagaa ggaatatgag gacggaaaag ctgctcagaa
     7621 aaagtatgaa gatgatcaga agaaaactga ggagaaagcg gaagaagaaa gaaaagcttc
     7681 tgaagaagaa caagctgcaa atctgaaata tcaacaagag ttggttaaat atatacgtga
     7741 aaatgatcca acaaaaaaag ctgaagctaa gaaagcaatg gatgaggctg agaaagagta
     7801 taagaaaaaa caaacggaat ttgctgaagt tcgtgcaaag gtaattccta gcgcggaaga
     7861 attaaaaaag actagacaaa aagcagaaga ggctaaagca aaagaagcag aacttactaa
     7921 aaaagtagaa gaagctgaga aaaaagttac tgaagccaaa caaaaagtgg atgcagaaca
     7981 tgctgaagaa gtcgctcctc aagctaaaat cgctgaattg gaacatgaag ttcagaaact
     8041 agaaaaagct ctcaaagaga ttgatgagtc tgattcagaa gattatgtta aagaaggtct
     8101 ccgtgctcct cttcaatttg aattggatgt taagcaagct aaactatcaa aacttgaaga
     8161 gttgagtgat aagattgatg agttagacgc tgaaattgca aaacttgaaa aagatgtaga
     8221 agatttcaaa aactcagacg gtgagcaagc tggacaatac cttgctgcag ctgaagaaga
     8281 cttagttgct aaaaaagctg aattagaaaa aactgaagct gaccttaaga aagcagttaa
     8341 tgagccagaa aaaccagctg aagaaactcc agctccagca ccaaaaccag agcaaccagc
     8401 tgaacaacca aaaccagcgc cggctcctca accagaaaaa ccagctgaag agcctgagaa
     8461 tccagctcca gcaccacaac cagagaagtc agcagatcaa caagctgaag gagactatgc
     8521 tcgtagatca gaagaagaat ataatcgctt gacccaacag caaccgccaa aagcagaaaa
     8581 accagctcct gcaccacaac caggttggaa acaagaaaac ggtatgtggt acttctacaa
     8641 tactgatggt tcaatggcta caggttggct acaaaacaac ggttcatggt actacctcaa
     8701 cgctaatggt gctatggcta caggttggct ccaatacaac ggttcatggt actacctcaa
     8761 cgctaatggt gctatggcta caggttggct ccaatacaac gattcatggt attacctaaa
     8821 cgctaacggc gctatggcta caggttggct ccaatacaac ggttcatggt actacctcaa
     8881 cgctaacggt gctatggcta caggttgggc taaagtcaac ggttcatggt actacctcaa
     8941 cgctaacggt tcaatggcaa caggttgggt gaaagatgga gatacctggt actatcttga
     9001 agcatcaggt gctatgaaag caagccaatg gttcaaagta tcagataaat ggtactatgt
     9061 caatggttta ggtgcccttg cagtcaacac aactgtagat ggctataaag tcaatgccaa
     9121 tggtgaatgg gtttaagccg attaaattaa atcatgttaa gaacatttga cattttaatt
     9181 ttgaaacaaa gataaggttc gattgaatag atttatgttc gtattcttta ggtacctatc
     9241 ttatgatttc aggaaatgtc attaaaaaaa cgactccttt tctctaactt gaaaaataga
     9301 ttagagaaaa tgggttgttt tatttattat agttatttga atgaagataa gaagaaggta
     9361 tactcacatc attcacataa tctgtatgtt gactataagt ttaaaaaaac aatttttaag
     9421 ctcttccttg tcttctccaa ccaagcgtgt tataatgaat actgctcaag cgaccttcaa
     9481 tcgtgaagca cacacgacct tcaatcgtga ataaacgaat agatgggaga cttaccatga
     9541 gtgataactc taaaacacgt gttgtcgtgg ggatgagtgg tggtgttgat tcgtcggtga
     9601 cggctctttt gctcaaggag cagggctacg atgtgatcgg tatcttcatg aagaactggg
     9661 atgacacaga tgaaaacggc gtctgtacgg cgaccgaaga ttacaaggat gtggttgcgg
     9721 tggcagacca gattggcatt ccctactact ctgtcaattt tgaaaaagag tactgggacc
     9781 gcgtttttga gtatttccta gcggaatacc gtgcagggcg cacgccaaat ccggacgtta
     9841 tgtgcaacaa ggaaatcaag ttcaaggcct ttttggacta tgccatgacc ttgggggcag
     9901 actatgtagc gactgggcat tatgctcgag tggcgcgtga tgaggacggc actgttcaca
     9961 tgcttcgtgg cgtggacaat ggcaaggacc agacctattt cctcagccaa ctttcgcaag
    10021 aacaactcca aaaaaccatg ttccctctgg gacatttgga aaagcctgaa gtacgcagac
    10081 tagcagaaga agcaggcctt tcgactgcta agaagaaaga ctcgacaggg atttgcttta
    10141 tcggagaaaa gaactttaaa aactttctca gcaactacct gccagctcag cctggtcgca
    10201 tgatgactgt ggatggtcgc gatatgggcg agcatgcagg tcttatgtac tatacaatcg
    10261 gtcagcgtgg cggactcggt atcggtgggc aacacggcgg tgacaatgcc ccttggttcg
    10321 ttgtcggaaa agatctaagc aagaatattc tctatgtagg acaaggattc taccatgatt
    10381 cgctcatgtc aactagccta gaagccagtc aagtccactt tactcgtgaa atgccagaag
    10441 agtttacgct agaatgtacg gctaaattcc gttaccgtca gcctgactct aaggtgaccg
    10501 tccatgtcaa aggagacaag gcagaagtta tctttgcgga accacaacgc gcgattacac
    10561 caggacaggc agttgtcttt tacgatggcg aagagtgtct aggtggcggt ttgattgaca
    10621 atgcttaccg cgatggacaa gtttgtcagt acatttagat tgacaaattt tctcaatttg
    10681 ctacaataat aacagcaata gaaatgatgg tcaaagctca tggatgttgc aggctttttt
    10741 gtcctgcact tctttgtagt tttgactgtt tttgtgtcgt ttaagggaaa ggacaagaat
    10801 gactcaacaa gactttcgga caaaagtaga caatacggtt tttggtgttc gggctacagc
    10861 cttgattgtc caaaatcaca agcttctagt taccaaagac aagggcaagt attacactat
    10921 tggaggtgcg attcaagtca atgaaagcac ggaagacgcg gtagtccgtg aagtgaagga
    10981 agaactggat gtcaaagctc aagctgggca gctagctttt gtggttgaaa atcgttttga
    11041 agtggacggc gtttcctatc acaatatcga gtttcattat ctggtggatt tgcttgaaga
    11101 tgccccgttg accatgcagg aagatgagaa aaggcagccc tgtgagtgga ttgacttgga
    11161 taagctccag aatatccagc tagttccagc ctttttaaaa acagccctac cagattggga
    11221 aggccaacta agacacattc atcttgagga ataggagaga aacatgactt atcattttac
    11281 tgaagaatac gatattattg taattggtgc gggacacgct ggggttgagg cttccttggc
    11341 cgctagccgt atgggctgta aggtcctgct tgcgaccatc aatattgaaa tgctggcttt
    11401 catgccttgt aatccctcta tcggtggttc tgctaagggg attgtcgtac gtgaagtcga
    11461 tgccctcggt ggcgagatgg ccaagaccat tgacaagact tacatccaga tgaagatgct
    11521 caacacaggg aagggaccag ccgttcgtgc ccttcgtgcg caggctgata aggaacttta
    11581 ctctaaggaa atgcgcaaga cagttgaaaa tcaagaaaat ctgacccttc gtcaaaccat
    11641 gattgatgag attttggtgg aagatggcaa ggttgtcggt gtgcgtacag ccacccatca
    11701 agaatatgct gctaaggctg ttattgtgac gacagggact gctctccgtg gggaaattat
    11761 catcggagac ctcaagtact catcaggtcc taaccacagc ttggcttcta ttaacctagc
    11821 tgacaatctc aaggaactgg gtctcgaaat cggtcgtttc aagacaggaa cccctccacg
    11881 tgtcaaggct tcttctatca attacgatgt gacggaaatt cagccaggag acgaagtgcc
    11941 taatcatttc tcatacactt cacgtgatga ggattatgtc aaagatcaag tgccatgctg
    12001 gttgacctat accaatggta ccagtcatga gattatccaa aacaacctcc accgtgcgcc
    12061 tatgtttaca ggtgtggtca agggagtggg gcctcgttac tgtccgtcga ttgaagacaa
    12121 gattgtgcgc tttgcggaca aggaacgtca ccaactcttc cttgagccag aagggcgcaa
    12181 tactgaggaa gtctatgttc aaggactttc aaccagtctg cctgaggatg tccagcgtga
    12241 cttggttcat tccatcaaag gtttggaaaa tgcagagatg atgcggacag gttatgctat
    12301 tgagtatgat atggtcttgc ctcatcagtt gcgtgcgact ttggaaacca agaaaatctc
    12361 aggtctcttc actgctggtc agacaaatgg aacatcaggt tatgaagaag ctgctggcca
    12421 agggattatc gcgggtatca atgcggctct gaaaatccaa ggtaaacctg agttgattct
    12481 aaaacgaagt gacggttata tcggggtgat gatcgacgac ttggtgacca agggaaccat
    12541 tgaaccttac cgtctcttga ccagtcgtgc tgaataccgt ctcattcttc gtcatgacaa
    12601 tgctgatatg cgcttgactg agatgggacg cgagattggc cttgtggatg atgaacgctg
    12661 ggctcgtttt gaaatcaaga aaaatcaatt tgataatgag atgaaacgcc tagacagtat
    12721 caaactcaag ccagtcaagg aaaccaatgc taaggttgag gaaatgggct tcaagccgtt
    12781 gacagatgcg gtgacagcca aggaattcct tcgccgtcca gaagtttctt accaagatgt
    12841 ggtggccttc atcggaccag ctgcagaaga cttggatgac aagattatcg aattgattga
    12901 aacagaaatc aagtacgaag gctatatttc caaagccatg gatcaggttg ctaagatgaa
    12961 acgtatggaa gaaaaacgca ttccagccaa tatcgactgg gatgacatcg attctattgc
    13021 gacggaagct cgtcagaagt tcaaactcat caatccagaa accatcggcc aagccagccg
    13081 tatttcggga gtaaacccag cagatatttc tattttgatg gtgtatctgg aaggtaaaaa
    13141 tcgtagtatt tctaaaactc ttcaaaaatc aaaatgatac gtcgtcggct tcttacgaat
    13201 gagttcaaag cttggctttg attcatctcc aacctcccat agttccccga actatgggag
    13261 ctaactcaag ttatgcattt tcctagcctt ctggtctgat tttcattgag ttttaatctc
    13321 aaaagaaagc atagagaaaa acagctccga agacggggct gttttgttga cttgtactca
    13381 atgaaaatca aagagcaaac taggaagcta gccgtaggtt gctcaaagca ctgctttgag
    13441 gttgtagata gaactgacga agtcagctca aaacacagtt ttgaggttgt agatagaact
    13501 gacgaagtca gctcaaaaca cagttttgag gttgtggata gaactgacga agtcagtaac
    13561 atatatacgg caaggcgaag ctgacgtggt ttgaagagta ttattcttca tctggtgtga
    13621 ggatcatcgg gatgatgatc ggttcacgtt cggtattttc atagaggaag gggcgaatag
    13681 cgttgacaat ggcaccattg acagattgca cgctagcatc cttatttttc agtgcgatac
    13741 gaatggcatt gaagaggata cgctggcttt ggcgaatcaa gtctccagac tctctcatgt
    13801 agacaaagcc tcggctgagg atatctgggc cagacagaat catctgcgat ttgaagtcaa
    13861 cagttgcgac tgccagaacg acaccgtctt cagatagatc gcgacgatct ttgaggacag
    13921 ctgcgccaat ttcaccgata cgatttccat cgacatagat atcttgggcg ttgaaatgac
    13981 ctgcgatacg agctgagtca gcagtaaggg caagcacatc gccattgctc atgataaaga
    14041 tattgtcttt ctcaacacca gtatccactg ctagtccagc gtggactttt tgcatgcggt
    14101 attcaccgtg gacaggcatg aagtattttg gcttaatcaa gcggagcatg agtttttgct
    14161 cttgctgacc accgtgtcca gatgtatgga tattgttcac tttaccgtgg ataacttcga
    14221 caccagcttc agaaatgatg ttaatcagct tgttgacgct agtagtgttt ccagggatgg
    14281 gactagaaga gaagataacg gtatcacctg gttgtaattg tacttgacgg tgggttccgt
    14341 tggcgatacg agagagggct gccataggct caccctgact acctgtacag aggataagaa
    14401 cttctcctgc aggataatct ttgatttcat ttggctcgat aaaggttccc ttaggagctt
    14461 tgatgtagcc aagatcgatt ccgttgacaa tggccttttc catagaacga ccaaagaccg
    14521 caatcttgcg tccagtctta acagcagctt ctgttgcctg ctggagacgg aagatatttg
    14581 aggcaaagga tgcaaagatg atacgtcctt caataccttg gataatcttc ataatggact
    14641 gaccaacgac tttttcagag ttggtaaagg ttggtacttc cgcatttgtc gagtcagaca
    14701 ggagacagag cacgccttct tcaccaagcg cagccatacg atgcaagtcc gcaggttctc
    14761 caactggagt aaagtcgaac ttaaagtcac ccgtacagac gattttccct tgaggagtat
    14821 gaatgacaat ccccaaaggc tctggaatag agtgagtcgt tctaaagaaa gttgccttga
    14881 gatttttaaa ggtcaactcg gtgttgtggt tgatttcgta aagtttggcg ttgcgcaaga
    14941 ggccgtgttc ttcgagtttc ccacggatca aagccaaggc aagcggtcca gcgtagatag
    15001 ggacatttgc ttgcttgagt aggaacggaa tcccaccaat gtggtcctcg tgtccgtgtg
    15061 tgattaaaac agccttgacg cggtcgatat tgtctacgat gtaagagtag tcaggaatga
    15121 catagtcgat accaagcaag tcatcttctg ggaatttaat cccagcatcg acgatgataa
    15181 tctcgtcttg gtattcaatt ccgtaagtgt ttttcccgat ttctcctaga ccaccgatgg
    15241 caaaaacacc gacttcttca ggtttaagag tgtaggccat attagaactc cgtaatttcg
    15301 aaggcgccag tttctttttc gtaatcgagc aatttgtcag acaagagttc gatatattcg
    15361 atattgtact ctgggcgatt ttcttcgaca agttggcgag cagtgatacg gccctcaagt
    15421 tctgagctgg catcgatgtc taggtaaagc gcgcgtgttg tttcacggcg tgggctacgt
    15481 tcttttgttt cttgataaaa aactttgtaa atcatatagt tcctttctat ttacaggtca
    15541 gcttattcca aacttttagc agatatttgc ttgatttcat tccattttgt gtctagattg
    15601 accttgattc gttacaatta tttcaattat accacaaaat gaaaaattag taaaagacgg
    15661 aaacgagaaa gttaggggac gatttcttcg gtaagcgttt gcaaaaacaa agaaaatgtg
    15721 ttatgttgat aacggaagtg aagtttatta cttgtcataa ttccatatag attttaagtc
    15781 aaggaggttg ccctatgtat aacttatttg cttttgctat cggagttcgt ttgctagctt
    15841 ttatcgtttt tgttttgcgt ttatggagga aatcttctat ttgccaaact ggaacgatga
    15901 caaaccaagt tcttgaggaa aattaccttt gtgactctct actcgctttt tctcctcctc
    15961 gtgacctatg tcgtttggtt tgtattttac tttggattaa atgcttagat gccctgctta
    16021 tgctggggtt ttttgtttgg ggatgtagag atagtagatt tacgacacga aaattccacc
    16081 ccatctatca agatgaggtg gtctttgcat ttttctaaaa tgatatgaca atggaatttt
    16141 caaagcttat tatttttatg ggagtcattg ttctgctcaa aaatagagtt gaagcataaa
    16201 aataaaacaa tacaaacaga taaatcgaat ggtaaaggga tggtagtaat gttcaaatca
    16261 ttgagaatgc tgagcaaact gtaagagatg aagacaataa aatttatcct tctaaaaatg
    16321 tgtttcttat ctagcatgac ttaccaaact ttttacgaag gtcttttcca atggtataac
    16381 ctgccataaa taaagcgata ccaacaccta caccaaagcc acccttgatt tcttgcaatt
    16441 ccttattaga aatttcacga cagttgttca aatctttcat catattaatc tcctcctaaa
    16501 aaataaccag ctgccaaacc agaacctata agtgctgttc cacctgcaat agctttccaa
    16561 gatactgcta ctccaaagat aaccaaggga gcgagaccgc catcaatatc tgataattca
    16621 ttttcagata aggataaaaa ttgattgtca agaatgtcaa aatttgtcat tgaactttcc
    16681 tccttttttc ttgttcactt ttatattcgg aaaagaaaag gaaaagtgag cattttttta
    16741 aattattttt agttaagtga gggcactctt gtctgggggc aaagaaaatt cccatgtgcc
    16801 atcttttgta gtataatagt aagcagacaa aaagatagga atgtgttatg aaagtattag
    16861 cttttgatac gtccagcaag gctctttctc tcgctatttt agaggataag caggttcttg
    16921 ccgagacgac gattaatatc aagaaaaatc acagtattac cctcatgcca gccattgatt
    16981 ttttgatgga gagtttggac tggacgccca aggatttgga ccgaatcgtg gtggcggaag
    17041 ggccaggtag ctacacaggc ttgcgaatcg cggtagccac tgccaagacc ttgactcata
    17101 ctctgaacat tgagttagtt ggtatgtcta gcctcttggc tctggtgcca tatcaacaag
    17161 aaggcttgtt cgttcctttg atggatgcgc gtcgcaacaa tgtttatgca ggattttatg
    17221 aaaatgctaa acctgtcatg ccagaagcgc acctatcttt tgaagaggtg ctagaaaaag
    17281 tcaagggtgc tagtcaggta acctttgtcg gagaagttgg cccctttgtg gagcagattc
    17341 aagaacactt gccaaggact aattataaag aaaccttgcc taatgcagcc aatcttgctc
    17401 ttttagcttg ggacaaggaa gcagactcct tgcatgattt tgtgccaaat tacctcaaac
    17461 gagtcgaggc tgaggaaaac tggctcaaga accataccga gtctggtgag tcctacatta
    17521 aacgcctatg atagaaatca agcgaattca acaacagcct gacctagctc aagccatcta
    17581 cgctgttatg gcagctgttt acctagtcag tccttggact ctggagcaaa tccaagcaga
    17641 tctgtcccaa gaccagactt ggtatgcatt ggcttatgat ggggcagaag tgattggatt
    17701 tctagctgtg caggagaatc tttttgaagc agaagtcctg caaatcgctg tcaaaggagc
    17761 ttatcagggt cagggaattg cgtcagcctt gtttgctcaa ttgccgacag ataaggagat
    17821 tttcctcgaa gtcagaaagt caaatcaacg agcgcaagca ttttacaaga aagaaaaaat
    17881 ggcggtcatc gctgagcgaa aggcctacta ccatgaccca gtcgaggacg ccattatcat
    17941 gaagagagaa atagatgaag gatagatata ttttagcatt tgagacatcc tgtgatgaga
    18001 ccagtgtcgc cgtcttgaaa aacgacgatg agctcttgtc caatgtcatt gctagtcaaa
    18061 ttgagagtca caaacgtttt ggtggcgtag tgcccgaagt agccagtcgt caccatgtcg
    18121 aggtcattac agcctgtatc gaggaggcat tggcagaagc agggattacc gaagaggacg
    18181 tgacagctgt tgcggttacc tacggaccag gcttggtcgg agccttgcta gttggtttgt
    18241 cagctgccaa ggcctttgct tgggctcacg gacttccact gattcctgtt aatcacatgg
    18301 ctgggcacct catggcagct cagagtgtgg agcctttgga gtttcccttg ctagccctct
    18361 tggtcagcgg cggacacaca gagttggttt atgtttcgga ggcaggagat tataagattg
    18421 ttggggaaac ccgtgatgat gcggttggtg aggcttatga taaggtcggc cgtgtcatgg
    18481 gcttgaccta tcctgcaggt cgtgagattg acgagctggc tcatcagggg caggatattt
    18541 atgatttccc ccgtgccatg attaaggaag ataatctgga gttctccttc tcaggtttga
    18601 aatctgcctt tatcaatctt tatcacaatg ccgagcaaaa gggagaaagc ctgtctacag
    18661 aagatttgtg tgcttccttc caagcagcag ttatggacat tctcatggca aaaaccaaga
    18721 aggctttgga gaaatatcct gttaaaaccc tggttgtggc aggtggtgtg gcagccaata
    18781 aaggtctcag agaacgccta gcagccgaaa tcacagatgt caaggttatc atcccccctc
    18841 tgcgactctg cggagacaat gcaggtatga ttgcctatgc cagcgtcagc gagtggaaca
    18901 aagaaaactt cgcaggctgg gacctcaatg ccaaaccaag tcttgccttt gataccatgg
    18961 aataaagagt ggctctttgt caagtgtagt gggtagtcga aaagctgcaa tctggagagt
    19021 acgaaattcg tactctcttt tttgatgttc aaagtcatca aaatccgttt tttaaaattg
    19081 ttaaagttcc ggaaaccaaa ggctttgcgc ttgataatct taatcaaatt attggtcgct
    19141 tcaagtttag cgttggaata aggcagctta agtgcgttga taatcttatc tctatccctt
    19201 aaaaaagtcc aaaagaccgt ttgaaaaagc ggatgaaccg ttggcagttc ttgctcaatc
    19261 aatccaaaga aatggtcggc attcttctct tgaaaatgaa agagcaggag ttgatagagt
    19321 tcgtagtgaa cctgtaatcc ctcagagtaa gaaagcagct tatctcgtac ttcccgatgg
    19381 gttaagtgca ttcgaaacgt gggctgatag aatcgtttct gacagagctt gaagctatac
    19441 tggtgtagta aatcagtcca gtggactgat ttagcccgag cctagaaacg aaaaagcgag
    19501 ggttccaaaa gcgcttgagc gcccgatact ccaaggattt tcggtcaaat tggttcatga
    19561 tttggattcg tactcggttc atagctcggc tcagatgttg gacaatgtgg aagcggtcaa
    19621 gaacaatctt cgcctttgga aagagttgct tagcgagccg ataataaggg ctgtacatgt
    19681 ccatggtgat gacctcgacc agctcccgaa cctctctctg atagcgttgg aaatggtttc
    19741 gaatcaccgc atgagttcgc ccgtctaaaa ttgcgaggat ggatttggac tcaaaatctt
    19801 gggcaatgaa gctcattttg ctctttttga agctatactc atcccaactc ataacttttg
    19861 gcaacttggt ccaatcggtt tcaaacttaa attccctcag ttttcggatg acggtggaag
    19921 ttgagaccgc caatctgtgg gcaatctcag tcatagactg cttttcaagg aggagctgag
    19981 cgattttttg tctcaccatg ttggaaatct ggcaattttt cttgacaatg gatgtttgag
    20041 aaacgaccac cttaaggcaa ttcttgcact gaaagcggcg ctttttgaga tgcagtaccg
    20101 tgggtaaacc ctgacagtcg agaagcggaa ttttagaggc tttctggaag tcgtatttga
    20161 tcatcttccc ttgacaatga ggacaaggag gagcggggga atccaacttt gcctgaacga
    20221 ctagatgggt ttggtatttc agaacagaca agattttgat atttttgtct tccaatccga
    20281 gcaaatctgt ggtattctta agttgttcca tatggaccct ttctaatgag ttggttagac
    20341 gcttttcatt ataggtcata tggggctttt tttctacaag aaacgaccct ataattcctg
    20401 gggtgggatt acccactaca gaaattatag agccaaagca ttccaaagtc ttgtctgact
    20461 ctggaatgtt ttctgttcac agttgttttg taactgccta ataagtaacc gcgctataac
    20521 gaggtatcta ccgagattgt caattctcca gtatactgtt ataaaaaaca aaactggagg
    20581 atttttttat gtcctcccat cgtcccatcg actgttccgt agctgcccaa taacggagta
    20641 tagtcggctg aaacaagaat aggacaaaag tgcctcaaga aaagcatcgt aatttgacaa
    20701 tattattctg agatgttttt gatgtaagcc catattttct caatgggatt atactcgggt
    20761 gaataggtag gaagtggtaa cagtctatgc cctgctcctt acacatgttc attctgtgaa
    20821 accttgcatt gtccataatg ataagggatg gtgtatctaa agtaggtagt aagaattttt
    20881 ggaagcaagc ttcgaaaaag tcactcgtca tcgtatcttt ataggtcatc ggagccatag
    20941 tatattgaaa caaaaaaggg cattagtact tctataacag tatcgcaatc tctggtgtgc
    21001 gttgtctcga tcttaattca aataattata tcttcttcca gagagactaa ctgcctgctc
    21061 aaggctcgat catatttgag ataaaaatag gtctcaaccc ctgtctcata aatataaata
    21121 ggagtcaggt agcttaagtg attcaattct ttaaggaacc gatttacttt ttctgggtct
    21181 tgttcgcagt aggtacggct ctttttagac tatatcccat agcctttaga gcgtaatgaa
    21241 tagttgttgg aggacagttg aattcagcag ctatttcagt caaataagca tcgggatgag
    21301 tttcaatata gatctttaat ttatctctat caactttttc aattaatagt ggaagttttc
    21361 ttaaagttag tgtgttgaaa cgtttttata cagtgctaaa atttgaagtg tagtgcagat
    21421 gtatttgtaa tagtattata gcaattcttt ggagaaggtc gagacaagag aaaataggta
    21481 tctttgagat ataagtatga tttactataa aattattgag ttattcataa aaatttctct
    21541 atcaaatatc ataatgcgtc gtttaaggag atggttacaa tgcaatatag ttgtggaaaa
    21601 ataaatatta atatccctga tggatatgga gacattaagg atatagtgtt ttcggctcat
    21661 attatagtta ggtataataa tggacattgt ggaggtatag atccgcatat aattggactt
    21721 tgtaaaaagc agatcagaag gatgtctcca tatcctattt tgataatcgt atctagagat
    21781 tcaaaggtta ttgatgatta taaaaattta gatattgcct atgttgattg tactcaatgt
    21841 tcaaataatt ttgaaactgc cttacacgtt aaaaatattt taaaattatt aaaaatccaa
    21901 cttatacact gtcatggcta ctcaactaat tattttttat atatgttaaa aaaacttgac
    21961 aagaatggat ttggaaaggt taagacagtg ataacatgcc atggatgggt tgaatataac
    22021 ttaaaaaaga aattcttgac ttattttgat ttttggacat attctatggg agatgctttt
    22081 atttgtgtat ctgaaactat gaaaaaaaga ttggagagta taataaaaaa ataagaagat
    22141 agttgcaata aataacggaa ttaatgtatc aaatagcgat ttagatgtag taggtgttca
    22201 agactttaaa aaagaatttt gtattccaaa taacaaaaaa atcatttgtt atgttggaag
    22261 gttggatcca gaaaaaaggc cggatagatt ccttgaattt gcagaaaaat tatttttagt
    22321 cagagaagat gtgattttta ttatggctgg aaatggtagt atgtgggcta ctttgaaaga
    22381 aaaaatttgc catttgaaat gtagagataa tttcaggtta cttggtgaaa tctatccagc
    22441 tactatagtt taccaaatat cggatttatt gtatattcct tctgatacag aaggaatacc
    22501 tatgtgtgtt ttagagtcaa tgtcacaaga aactccggtt ttagctagta atgttggcgg
    22561 gttaagtgaa attattgaac atagggttga tggattttta tttgagaagg aagatgttga
    22621 gggagtgtgt gcttgtgcta attttttact caatgattct gagtatttga aatatatagg
    22681 tgagaatagt aaatcaaaaa taagaaaaca tttttctgtg caaaaaatgt ttgtagaaac
    22741 catgagagta tatgatgaat tattagagaa gagtagtcat ggataggaat atagatcaag
    22801 aattagtaag tattataata ccaacacata ataggtatga atctctgatt agagctgtga
    22861 aaagttgttt acatcaaagt tataaaaata tcgaagttat aattattgat gataattata
    22921 gtaatgtaaa tttaagaaat aaaattatcc atcaatttgg ctataccagt catagaatta
    22981 agttaatttt aagtaatgaa gatttaggtg caactaatgc cagaaacata ggtatcaaaa
    23041 attctagagg taagtatata tcatttttag acgatgatga tgaatatatg ccagatcgaa
    23101 ttttaaagtt gatggcttgt tttaaaaaga gtagaatgaa gaatttagct ttagtttata
    23161 gttatggaat aataatttat ccaataggaa atattttaat ttattgagtt tcaacgagag
    23221 aatattggtt acaaagaaat attattcttt aaacataaag cggttactat taataggaga
    23281 caaatgcaag gctttaaaag taatcaagaa ggcaagagaa gaaaaaattt ttaacgaatt
    23341 tctttttcga aatatatgtt attatatcat tttggttttt tctattgtat atatgacaac
    23401 tatgttcaat taaaatttag aaagtgagaa actattgtgt atactattat aaaatcaaat
    23461 ataaaaaaat ttagtttatt aacgatattt attgttgctg gtcaattatt gctaatttat
    23521 gcagcaacta ttaatgctct ggtgttgaat gaattaattg cgatgaattt agagcggttt
    23581 ttgaaattgt caatctacca aatgattgtc tggtgtggga taatattcct tgactgggta
    23641 gtgaaaaatt atcaggttga agtgatccaa gagtttaatc tagagattcg aaatagagtt
    23701 gccacagaca tctctaactc tacctatcaa gaatttcata gtaaatcatc aggaacatat
    23761 ctttcgtggc taaataatga tgttcagact ttaaatgatc aggcttttaa acaacttttt
    23821 ttagtaataa aaggaatttc tggtactata tttgcagttg tgactcttaa tcactatcat
    23881 tggtcattga ctgtagccac cttgttttca ttaatgatta tgctacttgt accaaaaatc
    23941 tttgcatcga aaatgcgaga agttagtcta aatttaacta accaaaatga agctttttta
    24001 aaatctagtg agactatatt gaatggattt gatgtgttag cgtccttgaa tcttttatat
    24061 gtattgccta agaaaattaa agaagcagga attttattaa agatggttat acaaagaaag
    24121 acaactgtag aaacgttagc aggcgctatt agcttctttc tcaatatttt ttttcagata
    24181 tctctcgttt ttttaacagg ctatcttgca ataaaaggaa tagtgaaaat tggtactatt
    24241 gaagcaatag gagcactaac aggtgttatt tttacagcgc taggtgaatt aggaggtcaa
    24301 ttatcctcta ttattggtac gaagcctatt tttttaaaat tgtattcaat taatccaatt
    24361 gagtcaaata aaatgaatga tatcgaacca aatgaggtga atagagattt tccgttatat
    24421 gaagcaaaaa atatttgcta taagtatgga gataaagaaa tattaaaaaa cttaaatttt
    24481 tgttttcaac gtaatgaaaa gtatttaatt ttaggtgaaa gtggaagcgg gaaatctaca
    24541 ttattaaaat tattgagtgg ctttttgaga gattatagtg gagaattgcg attctgcggg
    24601 gatgatataa aaaaaacctc ctatttaaat atggtttcga atgttctata tgtagatcaa
    24661 aaagcttatt tgtttgaagg tacgattaga gataatattt tattggaaga aaattatact
    24721 gatgaagaaa tactacagtc tttagagcaa gttggtttga gtgtaaaaga ttttcctaat
    24781 aacattttag attattatgt tggtgatgat gggagattac tgtcaggagg gcagaaacaa
    24841 aaaattactt tagctagagg gctaattaga aataagaaaa tagtattaat tgacgaggga
    24901 acttctgcta tcgataggag aacttcgtta gcgattgaac gtaagatatt agatagagag
    24961 gatttgactg tcattattgt tacccatgct ccgcatccgg aacttaaaca atattttact
    25021 aagatatatc aatttccaaa ggattttatt taagaatata ggggagggaa acatgagatt
    25081 ctattgtgaa gcttatgagg taattactga agagaaaaaa gtatacttta atgatattga
    25141 gttagaagtt aagtattcct ctgtcgaaga attgtttata atatgtgaga aattattaga
    25201 taagaaaaaa gtatcatttt tttatgtata tgagaaaccc ttaaggtatc tgttatttga
    25261 ctatatattt ctactagttc tagctaaaaa aaatatccca atcttagatg gagtttccaa
    25321 taagcaagtt gatccaacgt tgctgcatca cttttctttg gaaattgaaa agaattttat
    25381 cgatttttgc tataaaaata tggatctcat cctaaaaact caaagtatat ctttgtgtca
    25441 tagagaagag cttattattg tagatgtttc agatgactct aaatttggtg ttttttacaa
    25501 gcgttttaga acactggttg ataaaaataa cggaaaatat gtttgtgttt ataatttcag
    25561 tcgtgtttca gatatactgc aaaactggaa aaattattgc aatcgaaaat tttcggttac
    25621 gtttactgaa agccaatttg aattatttaa gcttttatat aatcaaaaaa attttaaaac
    25681 aatttcgttg ctatttggaa aaaaattgtt gctggaggaa ttatctatta tagcgatctt
    25741 actaatatag aatacttttg tattttttgg tgggatagta tgtttgggaa agattctatt
    25801 ggaaaatacg tatatgtaga agagattagt agatgtcatt ttttagatag aaattattct
    25861 ttttgttatg gtttacaaga ttataaaagt aaacttatta aatatttttt agaatagtta
    25921 atctattcga gagagataaa gaaatatgga aaatacttta ttgaatatca caggaagctt
    25981 cgatatggaa actaggaatc taattagtta ttctttaact gatatctttg aaacagataa
    26041 aataagaatt gaacttcttg gagaaattta ttataaaaat ataaagttgg aattgcatga
    26101 attcgctgga ttgtataaga tttatggaat tagcttaata aagaatatta ccggaatgtt
    26161 tttaattata atttttgata cgaagacaaa agaattaaaa atttttcaag atataacgac
    26221 ttcatacttt aatttatact atactgttta tggaggtgtg ttctatatat agtacatctt
    26281 taaagaaagt gatgaagtta tctcatgttc ccgttacctt aaataacaaa aaaatacaag
    26341 aatttatgag aaatggattt attttagatt caaatacttt agtaaccgaa attaataaat
    26401 tagaatattt ctcttacatt tctgtaaata atactcttcg tatatgtggt attgattata
    26461 atgattcaaa caattttact aaagaacaag tattaaagaa ttgggactct atgctacgtg
    26521 aatctatatt aagagtgtat agtgaagcag gagaggctaa tattacacta tcatctggtt
    26581 ttgattcaaa ttatatatta tatacattag cgaattatac gaattcttca attaatgcat
    26641 tttgcatagg aggagaaaaa ggaattaatg agattcctga agtaactaaa attgcaaaat
    26701 tttatggtat aaatttatta gttgatactg taatgagccc aagatttaga atattttccc
    26761 gatatagtat ggagattgga aggaagtctc tttgaatgtg gtgtcatact gcagtactat
    26821 ttaggcaggt tgttgttcca aaaagggaac acaagtattc tttgtggcga gtcagcggat
    26881 gaaataatga cttttaagta tcattctgtg aactacaatc aattttgtaa tgataaacag
    26941 aagtcagtat attttagtta ttccgactat ccattttatg ttacaaattc aattgtttta
    27001 aagaaaaata gcctactttt gcatagtttt ggcattcatc ctagatatcc atataaaatg
    27061 tctgagattg ttgaaatgtc taaaaaaata tcagatctaa acgataaaaa agaatttcac
    27121 aaaaagaact gtgagttgag gtttcaagat agtgttcttg ataacataaa tagtgtcccg
    27181 ggtacaactc atttatttag ttgtttaaat attcaaacat tagtaaaaat tattttatat
    27241 atttttcgat acaacagttg tatgaaaata tttaatttta gagataaaga gcttatcttt
    27301 tttaataaga ttgtaaatgg gctgatacaa aatattgagg agaatttaga ggatgatatt
    27361 gaaaggatat tgaaatattt atatatatgt ttatttaacg aaatattcat tattaagaat
    27421 aaggtgaatt tttttgatga tgtggaattt aatcagacac ttagtgagtt tttagataaa
    27481 ttgtagaggg aatggttatg agtgacaata ctaagtatat ctttttatct ccacatttag
    27541 atgacgcaat tttttcctgt ggtgattata tttcaaaatt aacttcagaa ggagaaattg
    27601 tacttgttat tactatattt tctggttacc ctttgagcca acagctacag ccctctgcta
    27661 agcaatttca taagttgtgt aaccttggga aatatccgat tgaagaaagg aagaaagaag
    27721 acaggttagc ttgtgaacgt ctacaatgtg attttagaca cttatcgtac tatgaatgtc
    27781 tctataggaa agatagaaat ggcaattttc tataccgtca tatctatagt aaattaaaaa
    27841 atgaggacac attaaagaat gatatcataa aagagctgtt aatgcattta gacgacaaat
    27901 gtgtcgtata ttgtccgctt tcacttggtg accatgttga tcatgttttt gtgaatagta
    27961 ttggaagggc gcttgaattt atgcgttata aagtaatata ttatgaggac ttcccatatg
    28021 taagtgatag tagtatggtt agttatatgg gaaaaactaa agaattaaaa atgtatcaag
    28081 aggaacttga tgaaaaacat tatattgata gaatatcatc aatattgtgc tataaatctc
    28141 agattttgat aatctggaaa tcagttgaaa aacttttaaa caatattaaa gagttgtatt
    28201 taaggaatgg ggcagcttat tctattagat tttggattaa gaaataagga agtagtttta
    28261 tgaatatagc agtaattggt ttggggcatg ttgggctggc ctacgcgtta ctatttgcat
    28321 ctaaatataa agttgttgca tatgatatag attctgtaaa aataaataat ttaaaaaagg
    28381 gcactcttcc atctaaaaat gaagagctta tgaagttttt ttgcgagaat aacttaaata
    28441 ttactttttt tgatacattt tctgaaatta aaaataatat tgattattat attattgcgc
    28501 ttccgacaga ttatgatgag aaaattggta gttttaatac atatgaaatc gaacaaacgg
    28561 tatcgaagat tctgagggta aaacctaatg gaaagattat tttaaagtca acagttccga
    28621 tcggcttttc aaacaaatta aaaaggctgt ttgatacaaa aaatatcatt tttgtccctg
    28681 aatttttgag agaaggttgt tctatatatg ataatttata tccaagtcgc atagttgttg
    28741 gagatgagac agttgaagga agaaaaattg cagagttgtt cctttcgatt agtactcata
    28801 gtactgccaa tattaaaaat gttatgttag tttctcctac tgaagcagaa gcaattaagc
    28861 ttttttctaa cacattctta gctctccgtg ttgctttttt taatgaacta gattcttttg
    28921 ctgagaggag aagtttaaat gctgaagttg taataaaagg tgtttgttta gatccaagaa
    28981 ttggaaattt ttataataat ccttcttttg gatttggagg atattgtctt cccaaagata
    29041 ctagacaatt aaaaaaagaa tttatagaaa taaatgcccc agtgatagaa gcgattgata
    29101 tttcaaacac aaatagaaaa cagttcatag ttaaacaaat attggaacga aagccaaaga
    29161 tagtaggaat atataaattg gggatgaaat ataattcaga taattacaaa gagtcagcta
    29221 ttttaagtat aattaatgaa ctattgattg tcggtataaa aattttagta tatgaaccaa
    29281 atttaaacgt tagtatagat aacgtaattt ttgaaaagaa ttttgaacta tttataaaac
    29341 aaagtgatct aattgttgca aatagatggg ataggggcct tgaagcttat aaagataaag
    29401 tttacacaag ggggatctgg ataagagatt aactattgat attaaaaagg caataattta
    29461 taaaatttgt acaaaaaaat gttaaatttt cacattttca tagtatactg tttaatagaa
    29521 agtaggttct ttgtaaccgc tccattataa aatcctttca ctcttccggt atactattag
    29581 gaaaaacata actggaggat attttgagct cacacctcat cgttccagtg gctgttcccc
    29641 aagctcgtgt actgcccaaa aaagttagac attctattta gaacgaggat tgagttctgt
    29701 attgtacaag gctcggtcct tttagagtca gcttaaggct ggctttttca atcaccaaag
    29761 tgtcagaatg ttttgacaaa tgaacacaaa taatgatata atatgcaaaa gctaggaggt
    29821 ggtaggatga ttgaaaaaat ggaactgggg gaattttaca aggaattgcg cttggcgaga
    29881 aagctcaagc agtcagatgt ggcttgtgct ggactaacag cctctcagtt gtccaagttt
    29941 gaactaggac agtctatgct gtctgcagac aagctgatcc tagccatcca agggatcaat
    30001 atgaattttg atgagtttgg gcacaaactc aacaactatc aagaatctcc acatatgcga
    30061 attggtagaa gggttgtgga ttgcttttcc catcaggata tagctgcttt agagcagcta
    30121 ttggaggaag tcgatcaaga acagatggcg cagacctatc gtcgtttgaa tgccattgtg
    30181 attaaaaatg cactccattc cttagataaa agctacccgc taacagagga ggatagcgag
    30241 tttttgacta cctacctcta cgctattgag tcttggacct ggtttgaact ctatcttttt
    30301 tgcaatacta tgcccttctt gagcaatcaa gatctgatct ttttatcaac ctccttactc
    30361 gaaaaatcca aggaatttaa agagttagta cacaatcgat ggtatatgaa aagtggttat
    30421 cttaatatca tctcagaact tatggagcgc aagctatttt cttatattcc aatctttgaa
    30481 gctgagctgg agcgcatgct ccgtccatac gatgtttttg aaaaagtatt gtggcagttt
    30541 ttaaagaaaa tgcagatttt tcttcaaacc aaaggaagca atcaaaaaga gattgaacac
    30601 tttatccaat ctctgcaagt attagaaaat ccacaattga cagccctttt tgaattgcgt
    30661 ttgcagcaat acaaagagct tatcgattag ttagaaatgg gaaaaagata ataatatcag
    30721 caacgatcgt caataatgtt aaaacttgtt tcttcatatt acttccctcc tcattagtaa
    30781 taactttatt ataccaggga aataatcaaa tctaccaaaa tcgcaaatct gaaatttcta
    30841 taagaaaaaa tatcaaatat gcgattttct aaaataagcc aatttccgtg ttatactgtc
    30901 cttgtaaaac atttgaagca aatcctaggt cgcagaagtg gtttacaaat gaagataatt
    30961 gaaggagtgt aaaagatgtt aaatttacaa tttgcagaaa caatggaatt gacagaagct
    31021 gagttgcaag atgttagagg aggcaacctc gtaaattcta tgggaggtgg tggaagaagt
    31081 ggtatatctg gttggggcgt cccaggaatt taccctggtt ggggcaatca agggatgagt
    31141 cctaatcgtg gagcttttga ttggactata gatttagcag atggattgtt tggccgccgt
    31201 agaagatagg ctcttatagg agataatagg atgaagaaaa tgaaagaagt gaaatttcac
    31261 ctagcaactg gcttgttgat tttgacttat tacctcattt ttaatgtcac atcagactta
    31321 gattttatgg ttgctttgtc tgataatatg tactatgtgt tccaagtttt attggtactt
    31381 attctgggaa ctatagctac aattgctttt gtcaaaagtg aacattggaa agagtgtggt
    31441 cgtttccagt ttcgttggtc ttacctgggt gttttccttc tttctttttt cttattgttc
    31501 gtgtgggcaa atctaacaac ctatatcttt cctcgtaccc agaatggaag tacagtcgta
    31561 gaagtagcca ccagtttaac aggaattagc tattttgtta cgcgaatact ttatactagt
    31621 attatcgcac ctgtatcaga agaggttgtt tgtcgtggtc ttttgatgac aagtttatct
    31681 aaagttaaga gatactatct tgatgttctt gtttccgctg ccatatttgg cgctatgcat
    31741 gttttgcagt atggttggat aacgacagat ttcataaagt attttggaat gggcttgata
    31801 ttttgtatga tgtttcgcta cacccgatcc atctattggg ctatagctct gcatgcttca
    31861 tggaatagct tcttactcat tgttacttta ttggtatttg gatattagaa aggtgatata
    31921 tgaaaaagat aatctcacac cgctacttta ttatagtttt tctactagtt attgctgacc
    31981 agaagttcag tgttttagtt ttacgcagcg accttgttgc tgggctatct gactttgcct
    32041 attatctgtc ggatatgatg ttgaattttc ttgtggtttt atttgctctt attgctatga
    32101 tttggtcggg gaaatggcag aaaatcaata gtagaaagtt taaaggatcc tatcttttct
    32161 attccttcct agctctgctt gcttttgttg cttggaattt tgtcaccttt tttcttttcc
    32221 cacctactcg aaatgaaatt tcttatcaac atgctgctcc tacttttaca ggagctacgg
    32281 catttttgat gtattttttt tatcctgtga ttgcaggtcc catttttgaa gacatgattt
    32341 atcgtggatt ggtgatgaca gctctggaaa aaggaaagaa atgggggcta gatgtacttg
    32401 gttctgctat tttatttggg gtctcgcaca ttagtaatca cggttgggtc ttgacagact
    32461 ttttcgtcta tatgggtggc ggacttatat ttgcagtctt atttagaatg acaaagtcca
    32521 tttattggcc tattgggctg catatagtct acaacggcat tggtcagctt ttgatgttac
    32581 tgtaattttg gttgttagta gtatcgcggt ctatttctgg ggaaagattc ccatttgaac
    32641 ttaagaagga gttgtgatga aagtatttct tcaaaataga gattttaggc aattaactat
    32701 caaccagtgg atttcaacgc ttggggatac gattttttat ctggccttcc tgaattatgt
    32761 ggcagatgcg tcttttgccc ctttggcgat tttacttatc acgatttcag aaacccttcc
    32821 ccaagttcta caaatctttc tgggagtttt ggcggatttt caacatcatc gtgtcttgaa
    32881 atacacagtc attagtttta caaaattttt gctttactct atagtgtccc tatcgctttc
    32941 agggcagtct ttttccttgt tgctagtaac ctttatttgt ctgcttaacc tcttgtctga
    33001 cacattgagt tatttttcag gcgccatgct cactccgatt ttcattagaa ttattgggca
    33061 agaccatctg gcagaagcta ttggatttaa acagtcaact gttagtttag tgaaaacaat
    33121 cagtaatatc ctaggaggag tcttactagg cattctatcc atccagttta tttccttact
    33181 gaacgctctt acctttttaa tcgcattttt aggtatcctc ttcataaaaa ctgacctctt
    33241 gaaagtagaa aaaacgatta gctatcaaga aggactctct gtaaaatcct tttgccagca
    33301 tttgctccaa tcatcgaaat tgatatggaa tatgaataag gtgctcttgg ttttgtttat
    33361 tatctctact agtcaagcag tgataaatgt tacggttcct atttccactc tatttttaag
    33421 gaaccagccc tttttgaatt tacaaactgg tcaatctctt gccttgttag ccacactaga
    33481 attatcagcc cttattttgg gaagtctgat gagtggctat ctgcaacata ccatttccat
    33541 aaaaatagcc ctgtatgctt cactcctact ccaattacta ctcctagtgg gctttgcgac
    33601 agctcatttt ggcttgattc tgatctttag ctttttggat gcctttttcg cgggtattct
    33661 ctctcctaga ttgcaagaac tcgtctttaa acaaatacct gaggagtcaa tgggagcagt
    33721 tcaatcttct atcggtgcca ttacggttgt tttacctagc ttatttacaa tagctttggg
    33781 aaccattgct actagctttg gaactctggc agttagcttt gttttattac tatttcttct
    33841 agttgccttt gtcatgcttc tgaatattcg tgaaagtatt tagtggagaa tttctataat
    33901 atatgtttga gactggattg ccagtctttt tatgatggtc aaaatcaaca gactttttct
    33961 cttttctgaa tgtgttatag tagactgaat ctaaaatagt acgaaataat tgctaaaaca
    34021 tttatagaaa ttaattttac tttcccaatc gatttgttct catcttattt caatctgcta
    34081 tataatagtc catgctgtgg ctggattctt ttcagcctac ttatactctt cgaaactctc
    34141 ttcaaaccac gtcagcttca ccttgccgta ggtatggtta ctgacttcgt cagttctatc
    34201 cacaacctca aaacagtgtt ttgagctgac ttcgtcagtt ctatctgcaa cctcaaaaca
    34261 atgttttgag caacctgcgg ctagtttcct agtttgctct ttgattttca ttgagtatta
    34321 ttaagacaat atgaggagaa agatgaaaga aaaaggattt taggaggggg cgcaggcagc
    34381 catgccaacg gctcttggct atgtcagtat cggcctggcc tgtgggacta tcggtgcgcc
    34441 ctatgtgaca cctgttgaga tgggcttgat gagtctcttt gtttatgctg ggagtgccca
    34501 gtttgccatg ttggcactga ttgtggttca agctcctgtg gcagctattg ctatgacggt
    34561 ttttctaatc aacttgcgtc tctttttgtt gagtttacac gcatcgactt atttccgtca
    34621 taccagtctt tggtacaata tcggtatgtc tagtatcttg acagatgaga cctatggcgt
    34681 tttgatgggt gaattggccc atacagacaa ggtaaatcct atgtggatgc acggaaacaa
    34741 tcttaacagc tatgtggctt ggtttgtggg gacagtagtc ggaacggctc tgggtggcct
    34801 gctaccaaat ccagaaatct ttggcttgga ttttgccctg gttgggatgt ttattggtat
    34861 ttttgcttcg caatttcaga ttatgcaaag acggattcct gtccgcaatc tgctcattat
    34921 cctagcagtt gttgcggtgt ccttcttttt gctcttgaca gtggtgtctc agtcactagc
    34981 tgttctgttt gcgacgctac ttggttgtag catgggggtg gttttagatg gtcagtaagt
    35041 atcttttatt agcagttatt ttctctgact tggtgacttg gattctccgt atgattccct
    35101 tcatcttagt caagtataag ggcttgcctg caatcgttga gcgttttttg aagttcttgc
    35161 ccgtttccat tatctttgcc ttgattcttt caagcgtagt gacaggtaag gttgggagcc
    35221 ttcctcaaat taaatggcta gacttcttag ccgtctttcc aacagcttgg gtagcctttc
    35281 gctaccgcaa tctagtcgga acagttctct ttggagtagt cttgattgcc gtcttgcgtt
    35341 tggtctttta aatcagccat aaagaaaacc tatcacagat atatatatca tataatggtg
    35401 taaatgattt ttttctgtta agattataag gtattctatt ttggaggaaa tgacatgaaa
    35461 aaaatcgtta aatactcatc tcttgctgcc ctagggcttg ttgctgcagg tgtgctagca
    35521 gcttgctccg gtggtgctaa gaaagaagga caagcagcta gcaagaaaga aattattgtt
    35581 gcaactaatt cttcaccaaa accattcaac tatgaagaaa atggcgaatt gactggttac
    35641 gagattgaag tcgttcgcgc tatctttaaa gactctgata agtatgatgt caagtttgag
    35701 aagacagagt ggtcaggtgt ctttgcgggt cttgacgctg accgttacca aatggctgtt
    35761 aacaacatca gctacactaa agaacgtgcg gagaaatacc tttatgcagc cccaactgtt
    35821 aaagacccta acgttcttgt agtcaagaaa gacgattcta gcatcaaatc gcttgatgat
    35881 gttggtggaa aatcaacaga agttgttcaa ggaacaacat ctgctaaaca gttagaagac
    35941 tacaacaaac aacactcaga taatccaact atccttaact atactaaagc aaacttacaa
    36001 caaatcatgg gccacttgag cgatggtcag tttgactaca agatttctga taaaatcact
    36061 gttgaaacag tcatcaagaa ccaaggtttg gacaacttga aagtcatcga tcttccaagc
    36121 gaccaacaac cttacgttta cccacttctt gctaaaggtc aagatgagtt gaaaacattt
    36181 gtagacaaac gtatccaaga actctacaaa gacggaactc ttgaaaaatt gtctaaacaa
    36241 ttcttcggag acacttacct accggcagaa gctgatatta aataatttct tgaaatcatc
    36301 cattctgagt aagatgggtg atttttcagt tcgctaccgc aatctagtcg gaacagttct
    36361 ctttggagtg gtcttgattg ccatcttgcg tttggtcttt taaattaccc ataaaaaaaa
    36421 cttatcacag agatagatat catataatgg cgtaaatgct ctttttctgt taagattata
    36481 aggtattcta ttttggagga aatgacatga aaaaaatcgt taaatactca tctcttgcag
    36541 cccttgctct tgttgctgca ggtgtgcttg cggcttgctc aggtggtgct aagaaagaag
    36601 gacaagcagc tagcaagaaa gaaatcatcg ttgcaaccaa tggatcacca aagccattta
    36661 tctatgaaga aaatggcgaa ttgactggtt atgagattga agtcgttcgc gctatcttta
    36721 aagattctga caaatataat gtcaagtttg aaaagacaga atggtcaggt gtctttgctg
    36781 gtcttgatgc tgaccgttac aatatggctg tcaacaatct tagctacact aaagaacgtg
    36841 cggagaaata cctctatgcc gcaccaattg cccaaaatcc taatgtcctt gtagtgaaga
    36901 aagatgactc tagtatcaag tctctcgatg atatcggtgg aaaatcgacg gaagtcgttc
    36961 aagccactac atcagctaag cagttagaag catacaacgc tgaacacacg gacaacccaa
    37021 ctatccttaa ctatactaag gcagatttcc aacaaatcat ggtacgtttg agcgatggac
    37081 aatttgacta caagattttt gataaaatcg gtgttgaaac agtgatcaag aaccaaggtt
    37141 tggacaactt gaaagttatc gaacttccaa gcgaccaaca accgtacgtt tacccacttc
    37201 ttgctcaggg tcaagatgag ttgaaatcat ttgtagacaa acgcattaaa gaactctaca
    37261 aagacggaac gcttgaaaaa ttgtctaaac aattcttcgg agacacttat ctaccggcag
    37321 aagctgatat taaataattt cttgaaatca tccattctga gtaagatggg tggtttctca
    37381 gtttttaggg atatagtttt aaactatata tctgactatc taataacaat ttgtgaaatc
    37441 aaacaaattg tgagatacta gtacggtatt atttttaagg agaaagaatc atgaaaatca
    37501 aaaaatggct tggcctagca gcccttgcta cagtcgcagg tttggctctt gcagcttgcg
    37561 gaaactcaga aaagaaagca gacaatgcaa caacgatcaa aatcgcaact gttaaccgta
    37621 gcggttctga agaaaaacgt tgggacaaaa tccaagaatt ggttaaaaaa gacggaatta
    37681 ccttggaatt tacagagttc acagactact cacaaccaaa caaagcaact gctgatggcg
    37741 aagtagattt gaacgctttc caacactata acttcttgaa caactggaac aaagaaaacg
    37801 gaaaagacct tgtagcgatt gcagatactt acatctctcc aatccgcctt tactcaggtt
    37861 tgaatggaag tgccaacaag tacactaaag tagaagacat cccagcaaac ggagaaatcg
    37921 ctgtaccgaa tgacgctaca aacgaaagcc gtgcgcttta cttgcttcaa tcagctggct
    37981 tgattaaatt ggatgtttct ggaactgctc ttgcaacagt tgccaacatc aaagaaaatc
    38041 caaagaactt gaaaatcact gaattggacg ctagccaaac agctcgttca ttgtcatcag
    38101 ttgacgctgc cgttgtaaac aataccttcg ttacagaagc aaaattggac tacaagaaag
    38161 cacttttcaa agaacaagct gatgaaaact caaaacaatg gtacaacatc attgttgcga
    38221 aaaaagattg ggaaacatca cctaaggctg atgctatcaa gaaagtaatc gcagcttacc
    38281 acacagatga cgtgaaaaaa gttatcgaag aatcatcaga tggtttggat caaccagttt
    38341 ggtaataaga aacagggagg tgggagagaa aattccacct cttgcttttg tatagagtat
    38401 agattgtaaa gaagactatt cgttcataga aaggtagaga gaatatggtt tttcctagcg
    38461 aacaagaaca gattgaaaaa tttgaaaagg atcatgtagt ccaacattat tttgaggttt
    38521 tgcgtacctt gatttctaag aaatcagtct ttgcccagca ggttggactc aaggaagtcg
    38581 caaattatct gggtgagatt ttcaagcgtg ttggagctga agtggagatt gatgagagct
    38641 atacagcgcc ctttgtcatg gcacatttca agagttcgcg tccagatgcc aagaccttga
    38701 ttttctataa ccactatgac actgtgccag cggatgggga tcaggtctgg acagaggatc
    38761 cttttacgct ttcggtccgc aatggcttca tgtatgggcg tggggttgat gacgacaagg
    38821 gtcatatcac agctcgcttg agtgctttga gaaaatatat gcagcaccat gatgatttac
    38881 ctgtcaatat cagctttatc atggagggag cggaggaatc ggcttcaaca gacctagata
    38941 agtatttgga aaagcatgca gacaaactcc gtggggcgga tttgttggtc tgggaacaag
    39001 ggaccaaaaa tgccttggaa cagctggaaa tttctggtgg caataagggg attgtgacct
    39061 ttgatgccaa ggtaaaaagc gctgatgtgg atatccactc gagttatggt ggtgttgtgg
    39121 aatcagctcc ttggtatctc ctccaagcct tacagtctct tcgtgctgcg gatggccgta
    39181 tcttggttga aggcttgtac gaagaagtac aagagcccaa tgaacgagaa atggccttgc
    39241 tagaaactta tggtcaacga aacccagagg aagttagtcg gatttatgga ttggagttgc
    39301 ctctcttaca ggaggagcgg atggcctttc taaaacgttt ctttttcgag ccagcgctta
    39361 atatcgaagg aatccagtct ggttatcaag gtcagggtgt taagactatt ttacctgcag
    39421 aagccagtgc caagctagag gttcgtctgg ttccgggcct agaaccgcat gatgttctgg
    39481 aaaaaattcg gaaacaacta gacaaaaatg gctttgataa ggtagaatta tactatacct
    39541 tgggagagat gagctatcga agcgatatga gcgcaccagc cattctcaat gtgatcgagt
    39601 tggccaagaa attctatcca cagggcgttt cagtcttgcc gacgacagcg gggacaggac
    39661 ctatgcatac ggtctttgat gccctagagg taccaatggt tgcatttggt ctaggaaatg
    39721 ccaatagccg agaccacggt ggagatgaaa atgtgcgaat cgctgattat tacacccata
    39781 tcgaattagt agaggagctg attagaagct atgagtagag atattatcaa gttagatcag
    39841 atcgatgtga cttttcacca aaagaagaga accatcacag cggttaagga tgtgaccatt
    39901 cacatccaag aaggggatat ctacggaatc gttggatatt ctggagcagg gaaatcaacc
    39961 cttgtacggg tgattaacct cttgcaaaaa ccatctgcag ggaaaattac cattgacgac
    40021 gatgtgattt ttgatggtaa ggtcaccttg acggcagagc agttgcgtcg taaacgtcaa
    40081 gatatcggga tgattttcca gcattttaac ctgatgagcc aaaagacagc agaggagaat
    40141 gtagcctttg cccttaaaca ctctggactc agcaaggaag aaaagaaggc taaagtagct
    40201 aagttgttgg acttggttgg tttggcagat cgtgctgaaa actacccttc acaactatct
    40261 ggagggcaaa aacagcgtgt ggcaattgcg cgtgccttgg ccaatgatcc aaaaatcttg
    40321 atttcagacg agtcaacttc tgcccttgat ccgaagacaa ccaagcagat tttggccttg
    40381 ttgcaagatt tgaaccaaaa attaggcttg actgttgtct tgattacgca tgaaatgcag
    40441 attgtcaaag acattgccaa ccgtgttgca gttatgcagg atgggcattt gattgaagag
    40501 ggtagtgtgc ttgaaatctt ctcaaatcct aaacaacctt tgactcaaga ctttatctca
    40561 acagctacag gtattgacga agccatggtc aaaatcgaga agcaagaaat cgtggaacac
    40621 ttgtctgaaa acagtctctt ggtgcaactc aagtacgctg gagcttcaac agacgagcca
    40681 cttttgaatg aattgtacaa gcattaccaa gtaatggcta atattctcta tgggaatatc
    40741 gaaattctcg atggtactcc tgttggagaa ttggtggtgg tcttgtcagg tgaaaaagca
    40801 gcgttggcag gtgcccaaga agccattcgt caagcaggtg tacaactaaa agtattgaag
    40861 ggaggacagt aagatggaat cattgattca aacctattta ccaaatgtct ataaaatggg
    40921 ttgggctggt caggcaggct ggggaacggc tatctactta actctttata tgacagttct
    40981 ttccttcatt atcggaggct tcttggggct agtggcaggt ctctttctcg tcttgacagc
    41041 gccaggtggt gtcttggaga ataaagtcgt attctggatt ttagacaaaa ttacctcaat
    41101 ttttcgtgca gttcccttta tcatcctctt ggcaatcttg tcaccacttt ctcacttgat
    41161 tgttaaaaca agtatcgggc caaatgcagc ccttgtccca ctttcttttg cagtctttgc
    41221 cttctttgcc cgtcaggtgc aggttgtctt ggctgaattg gatggcggtg tcattgaggc
    41281 ggctcaagcg agcggagcga ctttctggga catcgtgggt gtttacctat cagaaggtct
    41341 tccagatttg atccgtgtga cgactgtgac cttgatttcc cttgttgggg aaacagctat
    41401 ggccggtgcg gttggagctg gtggtatcgg taacgtagcc atcgcttatg gatttaaccg
    41461 ctacaatcac gatgtgacca tcttggcaac catcattatc attttgatta tctttgcaat
    41521 ccaattcttg ggagatttct tgactaagaa attgagccat aaataaaaaa gagccgcgtg
    41581 gctcttttta actgatcaga ttttctgtgc aaatttttta ctcaaggctt gtccaatcaa
    41641 ggcacccact agggctccga tgacaatact tgcgataaat agaaggacag ttccagggtt
    41701 tggagcgacc atgatgcggt cgatatattc ttgggatttt cctcttgcca gaagagtagc
    41761 catataggct ttgggcgcaa tccacataag caagattggt cctgttgtac taaaggcgaa
    41821 aataatgaaa gaaaggaagt tctttgtttt gtccttgtat tttcctaaat gagctactcc
    41881 atctgctagg aggccacaga taattccagg aaggaaggaa ccagcaccgt gtttagttcc
    41941 caagaaaaag agggcaatga caaggccgat agtggtaatg gctccaaagc gcggaacttt
    42001 tgcgactagg atcatataga cgctaccgcc gacaagggca gtaaaggcag gcgcataaaa
    42061 catgtttcca gtttggtcaa agagattgcc caaaaggaca ccaatcccca tgcagaggaa
    42121 gtaaagaact gcaaaaagca gtgtagttaa gatagatttc ttcatgaatt gtctcctgat
    42181 aattttttca caattctcat tttaccatgg tttggtggga ttgtaaatgg atactagaag
    42241 tttttgaaaa cgcttgaaat atgatataat ggtttcatag ttatttttag gggaatatca
    42301 tgggtagatt tttagacttt gtctttaatc gtttcttttt agggatgatt gcgacagcct
    42361 tcttttggct attaacttta gcaggaggga ttatccttgg tctagcgccg gctagtgcca
    42421 ccttgatgag cttatatgca gaacatggtt atagctttcg ggaatacagt ttgaaggagg
    42481 cttggtctct ttacaagcaa aattttgtct caagcaacct gattttctat agctttttag
    42541 gtgtgggtct agttttgacc tatggtttgt atctcttggt gcaattgcct catcagacta
    42601 ttgttcattt gattgcgacc cttttgaatg tcctagtagt tgccctgatc tttttggctt
    42661 atacagtatc tttaaaatta caagtttatt ttgccttgtc ctatcgaaat agtctcaaat
    42721 tatccttgat tggcatcttt atgagtctag cagctgtggc caaggttctc cttgggactg
    42781 tgctacttgt agcaattggt tactatatgc ctgccctgct attttttgta ggaattggga
    42841 tgtggcattt ctttatcagt gatatgttgg aacctgtcta tgaaatcatc catgaaaaat
    42901 tggcgacaaa atagaatgaa gcagttttgg ctacatacgc ttctaagaac ctatagttca
    42961 gtgatgatca ttatcattgc gagttttgca atcttactct cttacgctga ctgggattca
    43021 cgtgaaaagg aagcccagag agtagcccag cgtgtaactg ctagaacagt gagtgaaatt
    43081 gaatattacc atagagagtc aacccagata gctcaggctt tagttgaaaa tcaagctcgt
    43141 attgagggaa tctataaata ctttagcctt agcatgccag actattttta ctggcaatta
    43201 gagcggaaag cttcgcctta tatatcagtc tctctgtatg aaaatgttga tgacctctat
    43261 gttcgaaatg attttgtaac tggggtggcc attgcttttc aagattacaa ggaagtctat
    43321 gtttctacta aagacaaacg tagtggagaa aaaatcaggg ctgaggattt caaaccagca
    43381 ggaaatagtt ttgccattcc ggtgtcagat ccagtgtcag atcaagattt aggagtgatt
    43441 tacatctcct tggatcctgc tgttttatac catgccattg ataatactag aggtcatact
    43501 ccgatggcag taacagtgac ctcacctttt gatacggaga tttttcatat tggtgagaca
    43561 gttgataggg agagtgaaaa ttggctagtt ggcttaactt ctcatggata tcaggttcag
    43621 gtggcagttc ctaaaaactt tgttttacaa ggaacagtga ctagctctgc tttgattgtg
    43681 ggtttgagcc ttctctttat tgtcattctt tatctgactt tgaggcagac ttttgctaat
    43741 taccaaaagc aggtagtgga tttagtggaa tccattcaag tcattgctca aggcgaagag
    43801 gggcgtcgga ttgacatttc cgaaaaagat caggaattac tcctaatcgc ggagacgacc
    43861 aatgatatgt tggatcgatt ggaaaagaat atccatgata tttaccagtt agagcttagt
    43921 caaaaagatg ccaatatgcg agccttgcag gcgcaaatca atcctcattt tatgtataat
    43981 acgctggagt tcttgcgcat gtatgcagtt atgcagagtc aagatgagtt ggcagatatc
    44041 atttatgaat tcagtagtct cttgcgtaac aatatttccg acgaaagaga gaccctcctc
    44101 aaacaggaat tagaattttg ccgtaaatac agctatctct gcatggttcg ctatcccaag
    44161 tccattgcct atggtttcaa gatagatcca gagttagaga atatgaagat tcccaagttt
    44221 accttgcaac cgctggtaga aaactatttc gcgcatggtg ttgaccacag gcggacagat
    44281 aatgtgatta gcatcaaggc tcttaaacag gatggttttg tggaaatttt ggtggtcgat
    44341 aatggtagag gaatgtcggc tgaaaagttg gcaaatatcc gagaaaaatt aagtcagaaa
    44401 tattttgaac accgagccag ctacagtgat caaaggcagt ctatcgggat tgtcaatgta
    44461 cacgagcgtt ttgtgctcta ttttggagac cgctatgcca ttacgataga gtctgcagag
    44521 caagccggtg ttcagtatcg tattacaatt caagatgagt agaaagggag aaaatgtata
    44581 aagtattatt agtagatgat gagtacatgg tgacagaagg tctgaagcgt ttgattccct
    44641 ttgataagtg ggatatggag gtcgtcgcaa cagccagtca tgccgatgaa gctctagaat
    44701 atgttcagga aaatcctgtc gatgtcatca tttccgatgt caatatgcca gacaaaacag
    44761 ggcttgatat gattcgggag atgaaagaga tcttaccaga tgctgcctat atcctgctct
    44821 caggttatca ggagtttgat tatgtaaaaa gagcaatgaa ccttagtgtg gtggactatt
    44881 tggtcaagcc tgttgataag gtagagctgg gaaatctgct ggagaagatt gcaggtcagc
    44941 tcggcgagag agggaagaaa agtcagactc ttagtcaaga attagacgag gctggatttg
    45001 ttagttattt aggggataag gagaattggt ggataggtct atccaaggaa aaacaaggtt
    45061 ccttcaccat tccctactat gtcttgggcc aagactggca gattttcatt tctgaccaac
    45121 ccctagatgg tttagtcgtt acaccttttg aagctcctta tcaagaacac tttgaacgct
    45181 ggaagctgaa tgctgagaaa accctctttt acggttctgt aaatttgcag cagtctgaga
    45241 gtctctttgc ctattacgaa ccgatttata gggttatcat tcagggaaat ctcaatcaaa
    45301 tcgtagaaga gttaaatctc ttggagaagg tagttcttga aaatacgccg cgtgttccga
    45361 ttactaaaca gctttttatt cagtttgtca tggatgtttt ccatttattt gaacatctca
    45421 aagctgatga cctgacagac atcgtcaaaa ccattcatgc tattcaatcc ttcgatgaat
    45481 tggttcctta tatcaaggaa actctgagca gctttttcgg tcaataccgt atgaatgaaa
    45541 atgtggtcag tgtgctggaa gtcattggtt gtgattacca aaaagagctt tccctcaagg
    45601 atatcagtaa ggctctcttt atcaatcctg tctatctagg gcagttgatt aagcgtgaaa
    45661 ccgattcgac ttttgcagag ttactaaaca aacaacgtat taaggctgcc caacaacttt
    45721 tgctttcaac tagtgacagc atcgaagata tttgttatgc tgttggttac agtaaccttg
    45781 gatatttcta taaagttttc cgaaaattgt gcggaaaatc gccaaaagcc taccgaaaac
    45841 aggtagaaac tatactataa gatttgtatt cctttacaaa atgtgctata atataaatat
    45901 tattattagg aggttctatc atgaaaaaga aaccaattta tctatgggtc ttgctaatct
    45961 tgtctgccct tatttcagtt ccgtctctgt ttggaattgt gagtcccttg cctagtaaag
    46021 aagcccttcg tactgctcag aaacaagttg caggggtcaa tgctcagcaa ttagaagacc
    46081 agcttaatta tacctataga gtagcagaag catctcattc tatttttaat gttgctttga
    46141 ttgtgctatc tactatttta gtggtcgtag cgattgtctt ccttgttcgt aaaaatttgc
    46201 aatatgcaaa ctatacttac gttggctatg ttttgttagc tattattggt tcgatttatg
    46261 gctatgttgg tttacaagac gctgtgcagt tggttcaaga tgagagcatg cgtttgacag
    46321 tgagtattgg ttcaaaagct gttagcattt tctatatcgt catcaatgtt ctcttcctag
    46381 cccttgtctt ctataagatg tggcgacaac agaaagcctc ggcagaagaa gaggaaacag
    46441 aagagcttgc ctaagtattg acaaaaaaga actatcaaga tacaatcttg gtagttgttt
    46501 tttgattata gataaaatca tggaggtaca tatgaagata atttctttag tttatattag
    46561 tttgagtggc aacactgaaa gttttgtgac gcgcttgaaa gactatctct tgtcccagta
    46621 caaagggatt gaggttcaaa agattcatat caaggattta gtcaaggaag gcaaaaattt
    46681 ctatgaaatg gaccatccct atgtcgcttt tttgccgacc tatctcgaag gtgggaatgg
    46741 cgtggataac ggagatgttg agattttgac gacaccggtg ggagatttta ttgcctatgg
    46801 taacaatgct agtaagtgtt ttggtgtggt tgggtcagga aatcgtaact ttaataacca
    46861 atactgccta acagccaagc aatacagtca acgctttggc tttcctgtat tggctgactt
    46921 tgaaatgcga ggcatgctgg aagatatcaa acatgtcgca gctattatcg cagatttgta
    46981 tgagttggaa aaggagaatt aatactcaat gaaaatcaaa gagcaaacta ggaagctagt
    47041 cgcaggttgc tcaaagcaca gctttgaggt tgcagataga gctgacgtgg tttgaagaga
    47101 ttctcgaata gtataaaatt cttataagag gtggttgaag ttgttcaact gttttttgag
    47161 tataaacagt ctttaagaac gtaaaaaagc ataagttcag gtcttcaaaa ccttgttctt
    47221 atgcttttta tcatagaaat atttgctgaa ttttctcttg aaatgaaacc ttatcttcat
    47281 ctcgcgcttg tcccttaccc tgcttttccg attgcgagtg cgtagataaa gaagatggcg
    47341 aagccaaaga ggaaaatcaa tcccgcaatg gcaaggtgtt tgagccaaga aggaagattt
    47401 ttgttttcac gcgttaccaa ggcgtaattc aaaagagcaa agaaaggtgt tgtcaggaaa
    47461 gagccaatca tggcaaagcg gagcatggtt gaaacctgac cagagaagaa cttgataatg
    47521 acgataccga tgatagcagt gatggtcatc cagatgttca aagatttacg attgtcctct
    47581 ttttgactga ttagcagtcg gagagattcc tgattaacgc gagaatagcc atcgataaca
    47641 gttataactg ttccaaagat acagaggaag gcaataaagg taatcaagta acgggaccat
    47701 tcgccaagaa cagaggcata catgcccacg aattgagaga tgtatttggc tgaagcagct
    47761 tcaaccgcct gccctgtagg atactgaatc agtgctccca gtgccacaaa gaagacggct
    47821 aggatagctg ttccaatata accagtgtta aagtcaaaca gagcgtcttc tgtgttaaag
    47881 ttgacggtct ttctcttttc agctgaccaa agtgaattga tggctgaaat ttcaatagga
    47941 gccggcatcc atcctaggag ggagacgatg aagggcagag ctgccatttg ccaaggtgtc
    48001 ttctcgacaa aatcagaact gtattctgga tgcttgaccg ccgcaatgat aactgccaga
    48061 acagtcgcaa tggttaaggc agacataatc catttgacca tgccgtctaa aagtttgtag
    48121 cctccaaaga gtagcatagc ccaaatgatt gcaacgagaa tgagggacca ctgagtaatg
    48181 ctaagtccaa tcattgggaa ggcactggcg atgatagctg agcacagaat ggcaacacca
    48241 gccgtgttga ccatagccga aaagacattg aggataaaga aaatccagag atagagtttt
    48301 cctttttcgg cataaccttc aaccaaagtc tttccagtat cagctgtgta ttcagcacca
    48361 aaacggaaaa atggatattt aaagacattg gctaagatga ccaagagaag tagagaccaa
    48421 ccgtaagaac cgccagcttg agttgaggat acaatgtggg aacctccaac agcggcagtt
    48481 gccattagga ttccaggtcc cattgctttt agcttgcttg cccaggttga ttgatttaag
    48541 gaaatagctt gcgacatgat aaatactcct ttttgaattt tcagaataat ctgtatatgt
    48601 aatctatatt ctacaaaaaa ttttggaaaa atgcaagaat attttgaaaa aagatagaaa
    48661 atttacaaag aaaat
//
LOCUS       DAVAZT010000007        48474 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVAZT010000007 DAVAZT010000000
VERSION     DAVAZT010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48474
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.007"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(308..1474)
                     /gene="recA"
                     /locus_tag="VQT45_000363"
     CDS             complement(308..1474)
                     /gene="recA"
                     /locus_tag="VQT45_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HET2358749.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            complement(1529..2785)
                     /locus_tag="VQT45_000364"
     CDS             complement(1529..2785)
                     /locus_tag="VQT45_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HET2358750.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNLLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQVDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGISSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(2869..3885)
                     /locus_tag="VQT45_000365"
     CDS             complement(2869..3885)
                     /locus_tag="VQT45_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET2358751.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEKALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(3893..4411)
                     /locus_tag="VQT45_000366"
     CDS             complement(3893..4411)
                     /locus_tag="VQT45_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2358752.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(4401..4844)
                     /gene="tsaE"
                     /locus_tag="VQT45_000367"
     CDS             complement(4401..4844)
                     /gene="tsaE"
                     /locus_tag="VQT45_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HET2358753.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(4930..5550)
                     /locus_tag="VQT45_000368"
     CDS             complement(4930..5550)
                     /locus_tag="VQT45_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2358754.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(5933..6796)
                     /locus_tag="VQT45_000369"
                     /pseudo
     CDS             complement(5933..6796)
                     /locus_tag="VQT45_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            6961..7155
                     /locus_tag="VQT45_000370"
     CDS             6961..7155
                     /locus_tag="VQT45_000370"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2358755.1"
                     /translation="MKKKRVSRMKKNRGIQKLAILVLLGVFMFSNTIPYQQFIQKNRQ
                     LEIRVQSQKKSNGLDVGKAD"
     gene            7470..7766
                     /locus_tag="VQT45_000371"
     CDS             7470..7766
                     /locus_tag="VQT45_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000911560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET2358756.1"
                     /translation="MLKFRKVVASSLAVLAFSLALPVLAVSHRGGEWTYGGHHDPNNW
                     GAFSNYYHGSQYHWAYVGSNGRNNQKTVYAGARSAAYAFVNTNFGEQVTFDAGW"
     gene            7869..9884
                     /locus_tag="VQT45_000372"
     CDS             7869..9884
                     /locus_tag="VQT45_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET2358757.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSYYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMNLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFIALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAGLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            9886..10518
                     /locus_tag="VQT45_000373"
     CDS             9886..10518
                     /locus_tag="VQT45_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2358758.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLTYLDLDKRIFELSGGESQRVALAKVILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDRLK"
     gene            10659..10937
                     /locus_tag="VQT45_000374"
     CDS             10659..10937
                     /locus_tag="VQT45_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComA"
                     /protein_id="HET2358759.1"
                     /translation="MKKFDNYIVEKPCDSNSDKLQKILIIENLVDDILQFPLRINNSV
                     GEIFLLQPFQKKTIFIPCYFEEDIVKVKDDDKVEWNLLEFQKFRAFLA"
     gene            complement(11446..11859)
                     /gene="ndk"
                     /locus_tag="VQT45_000375"
     CDS             complement(11446..11859)
                     /gene="ndk"
                     /locus_tag="VQT45_000375"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HET2358760.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(11970..15647)
                     /gene="rpoC"
                     /locus_tag="VQT45_000376"
     CDS             complement(11970..15647)
                     /gene="rpoC"
                     /locus_tag="VQT45_000376"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HET2358761.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGEVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPYAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(15680..19291)
                     /gene="rpoB"
                     /locus_tag="VQT45_000377"
     CDS             complement(15680..19291)
                     /gene="rpoB"
                     /locus_tag="VQT45_000377"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET2358762.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSSLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            19707..19777
                     /locus_tag="VQT45_000378"
     tRNA            19707..19777
                     /locus_tag="VQT45_000378"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19739..19741,aa:Cys,seq:gca)
     gene            complement(19975..21306)
                     /locus_tag="VQT45_000379"
     CDS             complement(19975..21306)
                     /locus_tag="VQT45_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HET2358763.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFNVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(21597..22421)
                     /gene="endA"
                     /locus_tag="VQT45_000380"
     CDS             complement(21597..22421)
                     /gene="endA"
                     /locus_tag="VQT45_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HET2358764.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLSQKKQ
                     APEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(22460..22648)
                     /locus_tag="VQT45_000381"
     CDS             complement(22460..22648)
                     /locus_tag="VQT45_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET2358765.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDSW
                     AILSPAKWQELIHKFTGN"
     gene            complement(22641..23924)
                     /gene="murA"
                     /locus_tag="VQT45_000382"
     CDS             complement(22641..23924)
                     /gene="murA"
                     /locus_tag="VQT45_000382"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET2358766.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(23948..24178)
                     /locus_tag="VQT45_000383"
     CDS             complement(23948..24178)
                     /locus_tag="VQT45_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HET2358767.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTAENTRKVRV
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(24236..25273)
                     /locus_tag="VQT45_000384"
     CDS             complement(24236..25273)
                     /locus_tag="VQT45_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HET2358768.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(25257..25745)
                     /gene="coaD"
                     /locus_tag="VQT45_000385"
     CDS             complement(25257..25745)
                     /gene="coaD"
                     /locus_tag="VQT45_000385"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HET2358769.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLCVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(25735..26274)
                     /gene="rsmD"
                     /locus_tag="VQT45_000386"
     CDS             complement(25735..26274)
                     /gene="rsmD"
                     /locus_tag="VQT45_000386"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HET2358770.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEVGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKTVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(26339..27331)
                     /locus_tag="VQT45_000387"
     CDS             complement(26339..27331)
                     /locus_tag="VQT45_000387"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HET2358771.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(27443..28126)
                     /locus_tag="VQT45_000388"
     CDS             complement(27443..28126)
                     /locus_tag="VQT45_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HET2358772.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(28182..28922)
                     /locus_tag="VQT45_000389"
     CDS             complement(28182..28922)
                     /locus_tag="VQT45_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HET2358773.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRNQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            28956..29234
                     /locus_tag="VQT45_000390"
     CDS             28956..29234
                     /locus_tag="VQT45_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HET2358774.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            29312..30238
                     /gene="yidC"
                     /locus_tag="VQT45_000391"
     CDS             29312..30238
                     /gene="yidC"
                     /locus_tag="VQT45_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET2358775.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(30313..31107)
                     /gene="pflA"
                     /locus_tag="VQT45_000392"
     CDS             complement(30313..31107)
                     /gene="pflA"
                     /locus_tag="VQT45_000392"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HET2358776.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(31233..32483)
                     /locus_tag="VQT45_000393"
     CDS             complement(31233..32483)
                     /locus_tag="VQT45_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HET2358777.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(32550..33377)
                     /gene="purR"
                     /locus_tag="VQT45_000394"
     CDS             complement(32550..33377)
                     /gene="purR"
                     /locus_tag="VQT45_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HET2358778.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLHEFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(33644..34585)
                     /locus_tag="VQT45_000395"
     CDS             complement(33644..34585)
                     /locus_tag="VQT45_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HET2358779.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(34575..35831)
                     /locus_tag="VQT45_000396"
     CDS             complement(34575..35831)
                     /locus_tag="VQT45_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HET2358780.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(35833..36495)
                     /locus_tag="VQT45_000397"
     CDS             complement(35833..36495)
                     /locus_tag="VQT45_000397"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HET2358781.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDGFVGVDRGSLWILE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFKQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLASYMHQIEIEDGQNLITYCPEGISQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(36458..37114)
                     /locus_tag="VQT45_000398"
     CDS             complement(36458..37114)
                     /locus_tag="VQT45_000398"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET2358782.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDGHFVP
                     QISFGAGVVEALRPHSKMVFDCHLMVSNPEHHLEDFVRAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALRDEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(37125..38003)
                     /gene="rsgA"
                     /locus_tag="VQT45_000399"
     CDS             complement(37125..38003)
                     /gene="rsgA"
                     /locus_tag="VQT45_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HET2358783.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDGGELDFYQQTYGDIGYDFVTSKEELLPLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     TAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGTIAPFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(38596..39369)
                     /locus_tag="VQT45_000400"
     CDS             complement(38596..39369)
                     /locus_tag="VQT45_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HET2358784.1"
                     /translation="MRKKLVNSLMCAVVLSGFPIATYANEKNIGPNITVSNGQTRLSI
                     PEKNGVEVIQSEENRVVYEVKEAAKIETSDGDMVAPIVVDSRITSINNQVVQGKTVYT
                     ADLEKATFVEEGYNKLAKPTNILDHIFGIQKVHAYTQNITTHQSQFDSTYSVELYTVV
                     HWVSYDGGVQKNITKISGGVDFHERDIEIESSSVEVRQGGWYSSQQKWFHPGARSSWE
                     YSTGFSKVGPGENRVVTNYTVNLIRYGDRWSAYLQNNPW"
     gene            complement(40059..40931)
                     /gene="rsmA"
                     /locus_tag="VQT45_000401"
     CDS             complement(40059..40931)
                     /gene="rsmA"
                     /locus_tag="VQT45_000401"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HET2358785.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAEVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPVPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLE
                     EFASLADALKGQGL"
     gene            complement(41182..41400)
                     /locus_tag="VQT45_000402"
     CDS             complement(41182..41400)
                     /locus_tag="VQT45_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2358786.1"
                     /translation="MENMTNPLLLVQIRVHGYLLDFASSEGQRQKHYRLKNLPQTVEL
                     TVDDVEEDVDLTLPENRSYQEADFFDTQ"
     gene            complement(41468..42109)
                     /locus_tag="VQT45_000403"
     CDS             complement(41468..42109)
                     /locus_tag="VQT45_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2358787.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(42111..44141)
                     /locus_tag="VQT45_000404"
     CDS             complement(42111..44141)
                     /locus_tag="VQT45_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET2358788.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEVLSHLAVEHNSLIARRIVEPNEAGETLFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLAATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQFICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSTYYQRLFTDYL
                     QNFSSESVEVTSQKYYLPQVSLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(44410..45309)
                     /locus_tag="VQT45_000405"
     CDS             complement(44410..45309)
                     /locus_tag="VQT45_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2358789.1"
                     /translation="MLIGQKIKEIRIEKGVSRPYFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPPAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(45381..45941)
                     /gene="rnmV"
                     /locus_tag="VQT45_000406"
     CDS             complement(45381..45941)
                     /gene="rnmV"
                     /locus_tag="VQT45_000406"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HET2358790.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINAQDIERI
                     QRLHQRQGVIVFTDPDFNGERIRRMIMTAIPTVRHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(45941..46714)
                     /locus_tag="VQT45_000407"
     CDS             complement(45941..46714)
                     /locus_tag="VQT45_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HET2358791.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     RALELVDEYDQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKVTDLQEAAKELPLDKILVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(47019..47912)
                     /locus_tag="VQT45_000408"
     CDS             complement(47019..47912)
                     /locus_tag="VQT45_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HET2358792.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLENTPGGDKGGNTGSSDANANAGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIVMVTVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(48196..48330)
                     /gene="rpmH"
                     /locus_tag="VQT45_000409"
     CDS             complement(48196..48330)
                     /gene="rpmH"
                     /locus_tag="VQT45_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HET2358793.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
BASE COUNT        13990 a        10915 c         9042 g        14527 t
ORIGIN      
        1 taaagctatt atatcagctt tccagaggag cgacaagaaa cagcaaactt atatatagcg
       61 gaatgaaata aggaaagtca aatcgatttt taacaatgtt ttagaagtag atatgtacta
      121 ttctagtttc gatctattat agttggttga gtttggaata gtacgctgta gctgctaaaa
      181 catttctaga aattaatttg actttcctaa tagagttgtt catatcttat ttcaagctac
      241 tatatataat ctaaaaactt gaatcaaaaa tcgaaaaagt agcggatttc tccactgctt
      301 taacagctta ttcttcaatt tcgatttcaa gttcatcgcc taagtcaagc ggaacttctt
      361 cattcactgc ttcttctttc tttggctcat cttttttgtt ttcagtatct tgttctgaaa
      421 cttcttctcc atcaatcaag ccaaatttag aacggacttg cttatcaatt tcatcaaaga
      481 tttctgggtg ctctgccaag tatttcttag cattctcaga accttgccca attttttcat
      541 ctttgtaaga ataccaagcc cctgcttttt tgataatatc caaatcgctt gcaatcttca
      601 aaagctcacc agtcttagaa attccttctc cgtacataat ttcaactacg gcttccttaa
      661 acggtggagc taccttattt tttacaacct taatcttagt ttctttaccg acattggttt
      721 ctttttggtc accagttccc ttaatttgtg tattaccacg aacatccaag cggactgaag
      781 catagaattt caaagcacgt ccgcccggtg ttgtttctgg atttccaaac atcactccaa
      841 ctttttcacg caattggttg ataaaaatgg caattgtttt ggttttattg atagaggcgc
      901 caagtttacg catggcctgg ctcatcatac gagcctgcaa accaacatgg ctatctccga
      961 tatctccatc aatttccgca cgaggaacaa gggcagcaac tgagtcgact acgacaagat
     1021 caactgcacc tgagtcaatc aattttcccg caatctcaag accttgctct cctgagtctg
     1081 gttgagacaa gagcaattcg tcaatattga caccaagggc cgcagcataa gctggatcaa
     1141 gggcatgttc cgcatcgata aaagcagcaa tcccaccttc tttttgcgct tgtgcaactg
     1201 catgaagggc aaccgttgtc ttaccagatg actctgggcc atagatttcg atgatacgtc
     1261 ccttaggata accacctgag ccaagggcaa tgtcaagagc taaagaacct gagctcatca
     1321 cttgcacctt ttgctccgca cgttcaccca aacgcatgat tgatccttta ccaaagtctt
     1381 tctcaatcaa tttaagagcg tcattcaagg ccttttcacg ttctgcccca aatttttttg
     1441 aaatttcttc taattttttt ggttttttcg ccattctatt ctcctacatt ctaatgatcc
     1501 tcagacctat ctactattat atcaaaaatt agtcacttaa taaagccttg cgaactaggt
     1561 taaaggcatg cataaccgca atgtgacgta catctgctcg gcttctgcct ccaatattaa
     1621 ccttgataac ctcagttcct tgatcttgcg ccaagcctat gaagactgtc ccaactgggt
     1681 gtccttctag gctatctggt cctgccactc cagtcaaact aattccaaaa tcagactggg
     1741 tcttgcttcg tgcctgctca gccatcttct gagctgtaaa ttcagacacc acaccatgtt
     1801 cttccaaatt cttggcagga atatccaaca tccttgattt ttcctccaag ctataggtca
     1861 caaaaccacc cttaaatata cttgaaattc cagaaaaatt cgccacggta gcttggaaaa
     1921 gacctgccgt caaactctct gcagccgcga tggttttccc ttgccttttc agttcttcta
     1981 ccacaatgct ggctaaacta gtttcttccc cataaccata gcaaaagtct cgtaaagaaa
     2041 ttccttcgaa agtctggcag tccaagattt gattttccaa gatatccagc gcttgattcg
     2101 cctcttcttg actgctagcc tttgttgaca gacgtagagt gacttctcct gtcttggcat
     2161 aaggggccaa ggtaggatcg acctgattat caattaaatc agccaaaatc gtaaccagct
     2221 ggctctcgcc aatcccaaag aaacgaagaa ctcgggaata cagcttgctc cctgtcatca
     2281 acttgggtag aagtaggttt aagaccatgg gtttcaattc acttggcgga cctggaagga
     2341 cgacataggt cactccgtct acttctaatt ttcctccaac agccagtcct gtttcgtttg
     2401 gcagtggaat cgctccttct acaatttgag cttgtctttc gttattcggt gttcgggcat
     2461 agtctggtcg cagggcaaaa aagatatcca acttctcctg agcctgagga tcaaagacta
     2521 atgctttccc taaaaattta gctagggttt gtttggttag gtcgtcctca gttggcccca
     2581 aaccgcctgt caaaatcacc agactgctac gttgactggc aatctcaagc aaagacaaga
     2641 gacgaacttc attgtctcct acagccgtct gaaaatatac atctacccca atctcagcta
     2701 gtttttccga caaaaactgg gcattggtgt tgacaatctg tcctgtcaaa atctctgttc
     2761 caacagcaat gatttctgct ttcatgtttc ctcctaccta tctattcgta tttttttgaa
     2821 aaaatcgcag gaattttcct acgattgatt ttttatttgt atcaaaagtt aattatcttc
     2881 atcaccaaca ggtgctctgc caaataaatc ttcaaataaa accgcattgg tttcaagctg
     2941 agtaacttct tcttgtccca aagaacgtcg gagtatattt tgcatttcca acatatgtgc
     3001 tcttgaaaca atctggtaag aaacaccttg aagtatctct ccttcaccct gcaactgctg
     3061 agtttcaatg gttttaaatg aatctttata gcctagcaag ttagggatac tttttgcaga
     3121 caaatcaata ttggtctgca tattgtcact caaagctttt agaatctctt gataatgacc
     3181 aacgctattt aaactgagag ctttttccat gactttttga ataacttcac gttgacgttt
     3241 ttgacgacca taatccccct caggatcttg gtaacgcatt cgtgcataga ctagggcttt
     3301 ttctccccca atatgttgct ccccaacacc gatagaaata gtattaaatt cttcttggtc
     3361 actgatagaa attgggaaac ctaggatatt attgactgta atacctccta ctgcatccac
     3421 tagtttttgc aaccctctca tattgaccat cacatagcga tcaatatgga tattcatcat
     3481 tttttgaatg gtttctatag caagctctgc tccaccatct gcatatgctg agttcagttt
     3541 cgcttcatga gcctgaccat tccctgattc aatgcgcgtc agaatatccc gctctaaact
     3601 catcattgtt gtttttttcg ttttaggatt cactgtcatc aagatcatgc tatcacttct
     3661 accgacccaa gtttcagttc gttcaacatt tccggtgtcc actcccatta acagaatggt
     3721 tagaggttca gtcgcttcaa taaccttggt ttcttcgccg atttttttat aggttttagc
     3781 taaggtttct gtcccttgtt gataaatagt ataagcaaaa acacctactc ctactacagt
     3841 tacagaaagt aaagctagca ccattccaat aattttttta accatatttc tactaaccta
     3901 tcagtttacc catcaagtaa acatcgataa atttcccttc ttctatatat gccccacgct
     3961 cttggctacc ttcaatgaca aagccatgct tttgataaag atggactgct gcttgattac
     4021 gagtttggac agtcagttgg agacgacgca gaatgccact tgcttgtgcc cactctatcg
     4081 cttcttctag caacaaactt cccaagccat tattccaata tctttttcca atcacaatga
     4141 agagatctcc aatatgacgg actctcttac gctgatcagc tgtaatattt acaataccag
     4201 caattttgcc atttaagaat gcaagtaagg ttatctgatt gtccgaacta gcttgcttgt
     4261 tgaggaatat ttccatctcc tcactagtca agagaatacc atctccgtct aggctggtaa
     4321 agtctgtctc caaactcaca cgatttaaaa aggccactaa ttcagctgca tctttgggct
     4381 ctgcttccct aatgagcaat tcatactcca tattgaagct cctctaacaa tttctcagca
     4441 cgcaaaccct ttgcctgaaa atttaaacgg cgtccatctg cttcttttag aatttccaat
     4501 tctaaataag catctggcaa ggcatctcct aagagatttc cccactcaat aacagtcacg
     4561 ccgccaccaa agataaactc atccaagtcg atagaatcag catctccttc aatacgataa
     4621 acatctaggt gataaagtgg aagtcgacct tcatactctc tcacgatagt ataggtggga
     4681 cttttaatca tttgagaaat ctgtaatcct tttgcaagtc ctttagtaaa ggtcgtttta
     4741 cctgcaccca gttctccagt taagattaaa acatcattct ttgctaatag atggcccaaa
     4801 cgctccccta aggcttgcaa ctcttcttca ttttttgtgt acatactctt attataccaa
     4861 aaacttttct tttgtgtcta ttttcctact aaacttatca tcataacatc cataaaaaac
     4921 aggctttctc taaaagaaaa tgagcgtaac aatgaccaat acaagatctc ggaaaatatg
     4981 accataaaag gaaacttcct tcttaaccga atttgggaca agataggctg caaaaaacaa
     5041 gcccagtcca atataaatca gaagtgagac aatggtcatt ggatttctta agaaaagaag
     5101 tgttgctaaa atagtcacca acactgtctt ttttctgtct agcatagcaa gaaaatcgcg
     5161 cacgtatttt ttcaagggta aaaaaatcag caaatctagc ccaaatagga aaaagaagga
     5221 tggcaataaa aagtcaacta attcttgctg cagcgtattt ttgatgaaca agttatctga
     5281 caaaacaaga acagctccta acaaattaat taagagtaac atactgtaaa aaagcttcac
     5341 cgacttctta ctggctagga cactatggac ttcttgctta cgggtataaa gataatttac
     5401 tccagcacag attcctgaaa cgaaaaccat gctcccgatg aaaaaagctg tactttgttt
     5461 aaaggacaag atgcattcct tccataggaa acagctactc aaactgattt gaattaaagc
     5521 taacaaaaat aagattctca ttgatttcat cttctctctc ccttcctacc aatcattata
     5581 ctaggagaaa agagagaact gtttctaatc ttctcaaatg tctctttaag acgctaaaca
     5641 aacactagag actaatactc aatgaaaatc aaagagcaaa ctaggtagct agccacaggt
     5701 tgctcaaaac actgttttga gattgcagat agagctgacg tgatttgaag agattttcga
     5761 agaatataaa tttgaaatca tgaaaatccg tcaaacgggt ggttgttttg tctcgcacct
     5821 cacggagcga gacggactca gagtcacata attataaggc tgatagtatt aatctaacta
     5881 tcagccttac aggttattta acgtttcaga aaaactataa tgtcaagatt aactaaacag
     5941 tatctaattc cttcaaataa ttttctatct tcatcagcat taaaggattg ttataaatct
     6001 tgcatagctc tcttgcttct atataataat ttttgacttg ttctctgtct agaaatttgg
     6061 ctccagcatt tcctacaaga ataagtagag gagccaattg gtagcttgtc tgtctttgtt
     6121 tacagagttc gatagtctca agagcttctt ggatggcttc attatatttt tcctttgata
     6181 ctaggtagtg agcgtaattg taacgaactc tgatgtagcc aaataaaaac tcttgatgct
     6241 caaaattttt tgtctgatat aactccatca aatgagagta gtttacctca tattcttgtt
     6301 cacgacccac taaggaatag aaattagata gagtattcaa cgcctttaaa taaatcaaag
     6361 tatttgagga gacttttaat aatatatttt ccaatgaaga aattgcttca cacttactgt
     6421 catattgaca gaagtcaata atagctttaa tccattcaag gtaagttcgg tcttctagtg
     6481 ttagaaaagt acttcgttca atctctattc tataaatata ttccaaattt tcataatttc
     6541 tatcatctaa taggcgagca gataattgct tgaaattaga gaggttagat ttaatttcaa
     6601 tttgttcatt aaaaaaataa tctaatggca cttcgagtcg ttgtgagagt ttgaacaaaa
     6661 ggtctgcgga gggaatgaaa taccctctct caattttact aatctggctc tattcacaaa
     6721 ttccttctgc aagagtttgt tgggagagtc tcaactcttt tcttttcaat ctgaatttct
     6781 ctgcgagtgt attcattaaa gataataaac cttcctattt gcttaatttc attataaaat
     6841 ttttagttca aaatagcaag ttaaaggaat aaataattct ttgcggtaat aaacaaaaaa
     6901 aagtcaaaaa ttacataaaa atgcttggct aaataaaata tatttgttaa aataaggata
     6961 atgaaaaaga aaagggtttc acgaatgaag aaaaatcgtg gaattcaaaa attagctata
     7021 ttagtattac taggtgtttt tatgtttagt aacacaattc cttaccaaca gtttattcag
     7081 aagaatagac aattggagat tcgagtccaa tcgcaaaaga agtccaatgg tcttgatgtt
     7141 gggaaggctg attgatttta tattacttta aaattcaact atttagagaa aggtattctg
     7201 atgagagctt gtaacaatac cagatagata taagaatgga gatgtttgat aaaatgcttt
     7261 catagctaac caactgttga aaattatgag ttacaaaatc taaagtattt aagattggtt
     7321 tataaaatta ggtctctgcc tgtagaaagg aacgtgcagt tagaaaggag gaaaaaatag
     7381 gatactataa ttcagactga gatttctaat taaaatatat agttgcattt cgctcatttt
     7441 cataatattt cattcagagg agtaataata tgttaaaatt tagaaaagta gttgcatcat
     7501 cccttgccgt tttggcattt agtttggctc ttcctgtttt ggcagtttct caccgtggtg
     7561 gcgagtggac ctatggaggc catcatgatc caaataattg gggagcattt tcgaattatt
     7621 atcatggttc acagtatcac tgggcctatg ttggaagtaa tggacgtaac aatcaaaaaa
     7681 cagtttatgc aggagcacgt agtgcggcct atgcgtttgt taatacaaat tttggggagc
     7741 aagttacatt tgatgcggga tggtaaagaa taattgaaga agattctttt atcaatagtt
     7801 cagtaagctt gttagtttat agagggcagg ggtatttctg ccctctgttt tagaataagg
     7861 aatgcactat gaaaaaatta tttatactca tatccaacct gcttgctagt ttgttctttg
     7921 tttgggtatt taccatttgg actgatacat atgtctccta ttattacccc aacgttgttg
     7981 tacatgattc ttcccctgaa acaacttttc agcatgttgc tacacgcttg gaaaaactag
     8041 cagaagaaac agatagcttt attgcgattc aacaccaaga tcctaactca gaaggtacta
     8101 cagttttttc ttatacgacc tttggggacg gaaagttgcc tgatgggctt caggaaaaaa
     8161 aactagaaga tgctcaaagt agtagtgttg aaacaaacta ttttgtattc gatggacacc
     8221 tagatattca cttgctaagg gaggagctaa gtcaacttgg cttgactaac atgaacctga
     8281 caattccatc taaactatct acgttaatgg ctatctttag taacggattt cagttaatca
     8341 gtctattgat tttcatctta acctttatag cactgacttt aattagtcaa attagccaat
     8401 tacggtcgtc gggcattcgc ctcatttcag gagagaaacg gtggtccatt ttccttagac
     8461 cagttggtga ggatttgaaa gggatagctg ttggtttcag tttagctggc gtgctcgcca
     8521 ttcttatgca aaaaattctg tcgcttccaa cgcaatccct aatgaccata ggagcaggct
     8581 tgctcagtta taatctcatc ttgttgtcga tctccctgtt tttcgctcaa ctcttcgcag
     8641 ttgggataaa aaagatacac ctgatgcaga ttataaaagg gcaagtgcct gtcagaggaa
     8701 tcattagttt gattttaatc ggtcaactat tagcgattat tattgtaacg ctgggaatag
     8761 ggagtagctt aaagtattcc caagcctggc aacagcatcg gattggacaa gaggcttgga
     8821 gtcaggaaag gcaactgatt accctatcaa tcagccgtga aggaacgagt cctggttttg
     8881 atgaacaagc tcaaaggaaa ctcagaactt ggtatcaatt gatggatctg gctgtttcag
     8941 aacaaaaggc tttcttatct agacaccagt taattgaccg tactttgcaa aatggcatgg
     9001 cttcctccaa aaacttgata acctctacag aatggcacga ttacaacccg aatggcaatg
     9061 tccttatcgt cacaccgcaa tacttggagc gtcaaaacat tcctgtagat acaactattg
     9121 agcaaaagat gaatcacctt gatgtagggg agtttgtctt attgctgcct gaacacctcc
     9181 gttcagagga agaacattat aaatctgttt ttgaagacga cttaaccagt cgcatgtcta
     9241 gtcaagatga acgacagcaa atgactgcta cggtaggtta tttagaatca ggtcaggatc
     9301 gttttgtgta taatacgacc cctatttctt accagcagtt tttgaaagat ccaatcatca
     9361 ttgttataac accccaatca actggtccac agtccatttt gttttggata gacgcagtac
     9421 agaactacgt tctctttaat caattgtctg atgcccagga gcttatccag agacaaggca
     9481 ttgaaaattg ggtctcagaa atgcaaacag gttaccacaa ctacatcaca ttattggata
     9541 atattcagag ggaacgttgg gtaatgctag caggagctgg gcttgggatt gcaacttcaa
     9601 tcttgttgtt taacactatg aataggctct actttgaaga atttagacgt gccattttta
     9661 tcaaacgcat tgcaggtctc aggttcttag aaatccatcg cacttatctc tttgctcaac
     9721 tgggtgtgtt tttactggga tttgttgcga gtgtatttct tcaggtagag ataggagttg
     9781 ctttcttagt cttgttactc tttactggtc tatctctttt acagttacat gtccaaatgc
     9841 agaaagaaaa caagatgtcc atgcttgttt tgaagggagg ttaatatgat tgaacttaaa
     9901 caggtgagta aatcttttgg agaacgagag ttattttcga atctttcaat gacatttgag
     9961 gctggaaaag tctatgcctt aattggttca agtggtagcg gaaaaacaac cttgatgaac
    10021 atgattggga aattagaacc ttatgatggg acgatttttt accgaggtaa agacttggcc
    10081 aattataaat cgagtgattt tttccgtcac gaattgggct acctcttcca gaactttggc
    10141 ttaattgaaa accaaagtat tgaagaaaac cttaagctag gtctcattgg tcaaaagttg
    10201 agtcggtcgg aacagcggtt gaggcagaag caggctttag aacaggtcgg cctgacttat
    10261 cttgacctag ataagcgcat ctttgagtta tcgggcggag aatcgcaacg ggttgccttg
    10321 gcaaaagtta tcttaaagaa tccacccttt attctggcag atgagccaac agcttcaata
    10381 gacccagcaa cttctcagtt gattatggag attctgctat ctcttcgaga tgataatagg
    10441 ctaatcatta tcgcaacaca taatccagca atttgggaga tggctgatga agtgttcacg
    10501 atggatcgtc tgaaataaaa atccttgttt ttaattgcac gatgagttac tgaaatatta
    10561 tcatgaatca ataattggag ttaatttaga attgtacttt attaatattg aggtaacttt
    10621 ttcttgataa aggaagaaat agtggagagg aagttagaat gaaaaaattc gacaattata
    10681 ttgttgagaa gccttgcgat tctaattcag ataaactgca aaaaatctta ataattgaaa
    10741 atttggtaga tgatattttg caatttcctc tcagaatcaa taatagtgta ggagagattt
    10801 tcctcctaca accgtttcaa aagaaaacta tctttattcc atgttatttt gaggaagata
    10861 ttgtgaaagt caaagatgat gataaagttg agtggaattt gttagaattt caaaaattta
    10921 gagcattttt ggcttagtaa tctgtgttga aggctcaaaa cctatggtaa aaaagtcgct
    10981 ttgaaaacgt attgcctcca aagatttagt taaataatga tttaacacaa aaagaaatta
    11041 ttgaagttct ggaaagatgt tgtttcagta ttgagaaaag gtgggaaaaa cttgcgattt
    11101 tcacagagaa aggaagaaaa agtatagaaa tatagtcaat tgaaacaaga acaggacaaa
    11161 agaacctttt gtgccatatt tttctccttt cgctttacaa ttggcttgaa cacctttatt
    11221 gtatcgcgtt tggagttttt ttggtataac cttcgacgcg cacccgcata gcgggtgttt
    11281 ttttgtctcg cacctaacgg agcgagacga actaatagtc acttaatcaa aaaacgcacc
    11341 atatcaaaaa ctaaaaagtt tgatatcatg cgtcatgtct taaactaatt gactatactt
    11401 tctattcaaa tgagctttta accaattgat tgagccaatc cactcttaaa accaaagagc
    11461 aatttctcgc ttagctgact cttctgaatc tgaaccatgt acaacatttt ggataacctc
    11521 attttctcca gcagcttttg caaaatcacc tcgaatagtg cctggtaaag cttcttctgg
    11581 acgagttgca cccatcatgg tccgccaagt ttcgattact ttgggaccag aaatgacacc
    11641 cacaagaact ggacctgaag tcatgaattc acgaatcggt gggtaaaaac tctgaccaac
    11701 caagtcctga tagtgctggt caatcaactc ttctgaaact tgtgaacgaa actccaattt
    11761 ttcgattgta aatccacgtt gttcgatgcg ctttaacact tcacccacta gccctctttt
    11821 tacaccatct ggtttgatga taaagaatgt ttgttccata cccgtctcct ttgtcagctt
    11881 ctttctttta ttttaccaca tttcgtggaa aaatggagaa agttttcaga atagagaatg
    11941 agagaacccg agggttctct cattctctat tattctactg tttcttccac agtttcaacg
    12001 gcagtatcca caactacttc tgttgtttct tcatttcctt cttcctctac tggaggatta
    12061 aggtattctt cttcgttgac agcatatggt tcaaggttac ggtaacgggc cataccagta
    12121 ccagctggga tgatcttacc gatgataaca ttttctttaa gtccaaggag atggtctttc
    12181 ttaccacgga tagctgcgtc agtaaggaca cgagttgttt cctggaagga agccgctgac
    12241 aagaaactgt ttgtttcaag tgaggctttg gtaattccca taaggactgg gcgacctgtc
    12301 gctggaactc cacctgcgat aaggacatct ttgttggcat ctgtaaagtc attgatatcc
    12361 atgagggtac ccatgagaag atctgtatca cctggatcca tgacacggac tttacggatc
    12421 atttgacgaa ccattacctc gatgtgtttg tcaccgattt ctaccccttg gctacggtaa
    12481 actttttgta cttcaccgag aaggtacgtt tcaactgaca agacatcacg aactgcaagg
    12541 agacgttttg gttggataga accttctgtc agagcagcac cacgcgctac ttggccccca
    12601 acttcgacac gcatacgagc tgtaaatgga acgacatatt caccttcgcc agtttcaccc
    12661 ttaacaaaga ctttcttggt acgagttgat gcatcttctt cgatagcagt aacttctcct
    12721 ttaacctctg tgataaccgc ttccccttta ggattgcggg cttcaaagat ttcttggaca
    12781 cgaggaagac cctgagtgat atcggtattt gaggcaaccc cacctgtgtg gaaggtacgc
    12841 attgtaagct gtgtaccagg ttccccgata gattgggcag caatggtacc aactgcttca
    12901 ccaacttcaa ccgcatcacc agtcgccaag ttgataccgt aacagtgacg gcagacaccg
    12961 tgacgagtgt tacatgtaaa tacagaacgg atagtcactt cttccacacc agcattgaca
    13021 atttcacgcg ccttgtcttc tgtaatcaat tcatttggac caataatcac tgcaccagtt
    13081 tctggatgtt taacagtttt cttagtgtaa cgaccgttga gacgctcttc gagagactcg
    13141 atcatctctt ttccttctgc gatagaacgg atcaagagac cacggtcagt tccacagtcg
    13201 tcctcacgga tgataacgtc ttgggcaacg tcgaccaaac gacgagtcaa gtaacctgag
    13261 tcggctgtct taagggccgt atcggtcata cctttacgag caccgtgagt tgagaagaac
    13321 atttccaata ccgacaaacc ttcgcggaag tttgaaagga ttggcaattc catgatacgt
    13381 ccattcggag cagccatcag accacgcata ccggcaagct gtgagaagtt tgagatgtta
    13441 ccacgggctc cagagtccat catcataacg attgggttct taggatcttg gttagcaatc
    13501 aagcgtttct caagtttttc acgggcagca cgccattcag ctgtaacagc attgtaacgc
    13561 tcgtcgtctg tgatcatacc acgacggaat tgtttggtga tttgctcgac acgtttgtgt
    13621 gattcttcaa tgatttcagc cttgtcatca acgactggga tatcggcaat acccactgtc
    13681 aatcctgcaa gagttgagtg gtggtaaccg agattcttca tgcggtcaag tagggcagaa
    13741 gtttctgtcg tacggaaacg tttgaagatt tcagcgatga tatttccgag gtttttcttc
    13801 ttgaacggag ggttgagctc aagattgctg atagcttcct tgatatctcc accaagtggc
    13861 aagaagtatt tagctggaac accttctgtc aagttggcat tgtttggttc ttgcaagtat
    13921 ggtagcccct ctggcatgat atcgttgaag agaattttac caactgttgt aagcaagacc
    13981 ttatgtcttt gctcttctgt ccaaggcttg ttgaggctgt ctgttgcgat accaacacgt
    14041 gagtggaggt gaacataacc attgcggtaa gccataaccg cttcgtcacg gtctttgaag
    14101 accattcctt caccttcgcg accagcttct tccatggtca agtagtagtt acccaaaacc
    14161 atgtcctgag atggagtaac taccggtttc ccatctttcg gattcaagat gtgctcagca
    14221 gctagcatga ggatacgagc ttctgcttgt gcttcttctg aaagtggtac gtggatggcc
    14281 atttggtccc cgtcaaagtc agcattgtag gcttcacaga caagtgggtg caagcgaaga
    14341 gccttaccat caatcaagac tggctcgaag gcttggatac ccaaacggtg aagggtcggt
    14401 gcgcggttca aaagcactgg gtgttcttta atcacttctt caaggatatc ccagatacgc
    14461 tcatctccgc gttccaccaa gcgtttagct gctttgacgt tttgcacgat atcacgggca
    14521 acgatttcac gcatgacaaa tggtttaaag agttcaatcg ccatttcacg tggcacacca
    14581 cattggtaca tcttaagagt tggaccaacg gcgataacgg aacgtcctga gaagtcaaca
    14641 cgtttaccga gcaagttttg acggaagcgt ccttgtttac ctttaagcat gtggctcaat
    14701 gatttcaatg gacggctacc tggtcctgtg attggacgac cacgacgacc attgtcaatc
    14761 aaagcgtcaa ctgcttcttg aagcatacgc ttctcatttt gaacgatgat acctggtgca
    14821 tttaactcaa gcaaacgagc caaacggttg ttacggttga taacacggcg gtaaaggtca
    14881 ttcaagtcag atgaggcaaa acggccacca tccaactgca acattggacg aagatctggt
    14941 gggataaccg gaagaatgtt aagaatcatc cattcaggtt tgtttccaga cttgtaaaag
    15001 gcatccaaaa catccaaacg acggatggct ttgacacgtt tttgtccagt agctgttttc
    15061 aattcttctt tgagttcagc aatttctttt tcaagatcta cttgcttcaa aaggtcttgg
    15121 atggcttccg cacccatctt ggcaacaaat gaaccataac catattcacg caagcgctct
    15181 cggtattcgc gctctgtcat gatagacttg tgctcaagtg gtgtatcctt aggatcaatc
    15241 accacataag ccgcaaagta gataacttcc tcgagggcac gagggctcat atcaagggtc
    15301 aagcccatac ggcttggaat ccccttgaag taccagatgt gagatacagg agctttcaat
    15361 tcgatatgtc ccatacgctc acgacgaact ttcgtacgcg ttacttcaac cccacagcgg
    15421 tcacaaacaa ttcctctgta acgaatgcgt ttgtacttac cacaagcaca ttcccagtct
    15481 tttgtaggac caaagatcac ttcatcaaag agtccttcac gttctggttt caaggtacga
    15541 taattgattg tttcaggttt tttgacttct ccataagacc atgaacggac tttacttgga
    15601 gaagctaggg tgatttgcat acttttaaaa cgatttacat caaccactat ttcttccctt
    15661 tctattctaa gtgaactgct tattcttgtt cagcagcttc ttctgttgct tccgcttttg
    15721 ttgctttctc agcttcttca gcttcaaagg ctgctttagc ctcttgagct gctttttcgc
    15781 gggctttttc aaggtcatct acgtggatga catcttcgtc cattccttca tccaagtcgc
    15841 gaagttccac ttcttggtca tcttcgtcta ggacacgcat gtcaagacca agagattgca
    15901 attctttgac aagaactcgg aaggattctg gaacacctgg ttttggaatt ggtttgcctt
    15961 ttgtaatagc ttcataggct ttcaaacgtc cgttgatatc gtccgacttg taagtcaaga
    16021 tttcttgaag gacatttgac gcaccgtagg cttcaagagc ccaaacctcc atctcaccga
    16081 aacgttgtcc accaaactga gctttacctc cgagtggttg ttgggtaaca gttgagtaag
    16141 gtccgactga acgcgcatgc aatttatcgt caaccatgtg gtggagtttg atcatgtaca
    16201 tgactccaac agaaacacgg ttatcaaatg gttcacctgt acgtccatcg taaaggattg
    16261 tcttggcatc gctatccata cctgcttctt taacagttga ccaaagatct tcagaacttg
    16321 ctccatcaaa gactggtgtc gcaatgtgaa taccaagagt acgagctgcc ataccaaggt
    16381 gaagctccat aacctgaccg atattcatac gtgatggcac cccaagtggg ttcaacatga
    16441 tgtcgactgg agttccgtct ggaaggtaag gcatgtcttc tacaggaacg atacgagaga
    16501 caaccccttt gtttccgtga cgtccggcca ttttatctcc gaccttaatc ttacgttttt
    16561 gagcgatgta aacacgaacc aacatgttaa cacctgattg caactcatct ccatttacac
    16621 gtgtaaagat cttaacatca cgaacgacac catcggcacc gtgtggtaca cgaagagaag
    16681 tatcacgcac ttcacgagac ttgtctccaa agatagcgtg caagagacgt tcttcagctg
    16741 aaagatcttt ctcaccctta ggtgttactt tacctacaag aatatcacct tctttaacct
    16801 cagcaccaat acggataatc cccatttcgt caaggtcttt gagggcatct tcaccaacgt
    16861 ttggaatttc gcgagtgatt tcttcaggcc caagctttgt atcgcgcgtt tctgattcgt
    16921 attcttcaag gtgaacagat gtgtagacat cgtccttcac caagcgttcg ctcatgataa
    16981 cggcatcctc gaagttgtaa ccttcccaag tcatgtaggc aacgattggg ttttgtccaa
    17041 gcgccatttc tccattttcc atagaaggtc cgtcagcgat gaaatcgcct ttttcaacga
    17101 catcaccaac ttttacgaga gtgcgttggt tgtaagcagt acctgagttt gaacgacgga
    17161 atttttggat gtggtaaaca tccaatgaac catcttcacg acgaacttct accttgtcag
    17221 catctgcgta agtaacttta ccatcatact gagcaatcac agccgcacca gaatcgtggg
    17281 ctgcttggta ttccatacca gtaccaacgt aaggtgcctg aggattaatc aatggcacag
    17341 cctgacgttg catattggct cccatgaggg cacggttgga gtcatcgttt tccaagaaag
    17401 gaatacatgc tgtcgcaacg gcaactacct gttttggtga aacgtccatg tagtcaacaa
    17461 tattagctgg atactcttgg ttgacccctt ggtgacgtcc catgacaatc ttctcagcaa
    17521 aggttccatc ttcattcaga ctagagttag cctgagctac agtatattca tcttcttcat
    17581 cagctgtcaa ccaaacaatt tcgttcgtga caacacctgt ttcacggtca accttacggt
    17641 atggtgtttg aacaaaacca tatttgttca agtgtccgta agatgacaag ttattgatca
    17701 aaccgatgtt aggtccttca ggtgtctcga ttggacacat acgaccatag tgagtgtagt
    17761 gcacgtcacg tacttcatat ccagcacggt cacgagtcaa accaccaggt cctaaggctg
    17821 acaaacggcg tttgtgagac aactcagaaa gcgggttgtg ttggtccatg aactgtgaca
    17881 actgtgatga accaaagaat tctttaactg cagctgttac aggacggata ttgataattt
    17941 gttgtggtgt caagacttca ttgtcctgaa cagacatacg ttcacggaca ttacgttcca
    18001 tacgagaaag tcccaaacgt acttggttgg caagcaattc accaaccgca cggatacgac
    18061 gatttccaag gtggtcgata tcatctacac ggccaagtcc ttcagccaag ttgaggaagt
    18121 agctcatctc agcaaggata tctgcaggag tcaccgtacg aaccttgtca tctgggttag
    18181 cattaccaat gatcgttacg acgcgatctg gatcagttgg agcaacaacc ttgaattttt
    18241 gaagaacaac aggctcagtc acaacggctg catcgtttgg gatgtagaca atcttgttca
    18301 agtcgccatc caaatggctt tcaatgcttt caatcacgct acgagtcata atcgtaccag
    18361 cttctaccaa gatttctcca gtttcagggt ctaccaatgg ctctgcaatg gtttggttga
    18421 gcaaacgtgt tttaacattg agttttttat tgattttgta acgaccaact gctgccaagt
    18481 catagcgacg tgggtcaaag aagcgagcca caagcaagct acgtgagctt tcagctgtct
    18541 taggctcacc tggacgaagg cgttcgtaaa tttctttcaa ggcttcgtct gtacgagagt
    18601 ccattggatt cttgtggata tctttttcaa cagtgttgcg aaccaattcg ctgtcaccaa
    18661 agatatcaaa gatttcatca tcacctgaga aaccaagagc acgaaccaag gttgtaaatg
    18721 gaatcttacg agtacggtcg atacgagtgt aggtgatatc ttttgagtcg ctttcaagtt
    18781 ccaaccaagc tccacggtta gggataacag ttgaaccata gcccacctta ccatttttgt
    18841 ctactttgtc gttaaagtaa acacctggtg agcggaccaa ctgagaaacg ataatacgtt
    18901 caccaccatt gatgatgaaa gtacccattt ctgtcatgat tgggaaatca ccaaagaaaa
    18961 cttcttgggt cttgatttcg cctgtttctt tattgatcaa gcggaaggtt acaaaaattg
    19021 gtgctgagta gctagcatcg tggatacgag cttcttctag cgtgtatttt ggttccttga
    19081 tttcatatcc aacaaattcc aactccattg tgtctgtgaa gtttgaaatt ggcaatacat
    19141 cttcaaacac ttccttaaga ccgtggtcta ggaaagcttt gaatgagtca gtttgaattt
    19201 caatcaaatt tggtaagtca agaacttctt tgattcttga aaaactacga cgggtacgat
    19261 gtttcccgta ttgaacgtca tgtcctgcca agatgattct cctttgtaaa taagttccaa
    19321 gccttgtcaa tcaggctttt ctaatcgcca tatggttgta aaccccttat caccgtgtcc
    19381 tcttgacgaa ttttcagaat ctttaagcct ctgttacaaa tgctcaaaat cttgaaaaaa
    19441 agcacaaaaa gagcagctaa atctgacttt ttcagaagat ttaactgctg tgagccttgt
    19501 ctggacaata tttcagacaa aacctacgac aaatgattac ccatattata ccctatttag
    19561 ctagattttt caaggggatt cagtaggttt ttggtaattt ttttcccata gaaaacttgg
    19621 catcacattc gaatcacgct atggtacaaa aaactgaaaa aactattgac tgaaaatcat
    19681 tttcaaggta taataataaa cgttaaggcg gtatagccaa gtggtaaggc acggctctgc
    19741 aaaagcttga tcgtcggttc aaatccgtct accgccttct ataacttgat ttatcaggtt
    19801 tcaaatgaac agaaagccca atttgaaggg ctttttttat tttccctcga ataaatacgt
    19861 ataactttaa aaacttttgg agcgagtttg tggcagagtt ctttccatgg cataattccc
    19921 ttttgaaatc aattgaaaaa agcttcgtca cgcctggtga caaaagcctc tagtttattc
    19981 tgtttcttct tctatttcga cttctgtgat ttggactttt accttggtaa cacgtccatt
    20041 cttcacttta tcattggtta agataaactg tttgttttgg ctgaccaatt catagctgag
    20101 tttctcagtc gttggaatgg ttcccactcc tgtcaaataa taaccagcga tagtatcaac
    20161 gtcatcactt tccagttcaa cattaaagta attattgaaa tcattgaggg tcatagttcc
    20221 ttgaacaatg taggtatcct cgccaatctg atgaacatct attgctgctt tgtccgtttc
    20281 atcatcaatt tcaccaacaa tttcctctaa gaggtcttcc aaagtcacca aaccagccat
    20341 accaccgtat tcatccagca agattgccat ttgtctttgg gtatttcgca gttcttttag
    20401 caagtcatcc acaaaaatag tttcaggtac aaaaagtgga tcttgtaaaa ttctcttcca
    20461 aacaatattg tcaaaaccgt ccacaaagcc tgccttaagg agactcttgg tgtgaatgat
    20521 tccaattaca ttgtccttat ccccatcata aaccgggata cgagaataat tttgttttaa
    20581 aatactttgg ataatggctt gactatcatc ctgaatatcc accataaagg catccgttcg
    20641 aggaaccata acctctcgtg ccatcagttc atcgagcgaa aagacacctt gtaacatctc
    20701 aatctcatca gcatccaatg tttcttcact atttgtcagc atataggcaa tttcatcacg
    20761 ggtcatcttt tcatccgcat catcgaatga cataggagtc aaatggctca agaaattggt
    20821 cgaagcagct aaaagccaaa caaaaggact gactagtttt ccgatcccaa tgataaccgg
    20881 cgctgtacga attgccaagg catcctttag attaagagcg attctcttag gatataattc
    20941 cccaaaaacg atggaaatat aggtcaaaaa tgccaaggat agaaaagttg ccacggcttg
    21001 tgctgtttcg ccattcccaa gccaagaggc aatcacacgt cctagagtat cagttaaact
    21061 cgcccctgat aagattgtaa tcagggtgat tcctacctga atggttgata aaaagtggtt
    21121 aggattttct agtaccttca gcaggcggat gtagcgtctg tctccttctt ccgccttttg
    21181 ttcaactcgg gcacgattaa gagaaaccat ggccatttct gtggctgaga aaaaggcatt
    21241 taataccgtc aagataaaca ataaaacaaa ttgtagcaac aaattctgac tacttgggtc
    21301 ttccatagtt cttctcctaa aatagtatct tatcctttat tatatcacaa aatttaatcc
    21361 aatacatatt atttttttct tagcgtaact tccatctctc tcccaaaact ggaagttagt
    21421 ctaagacgga tttccactga tttcacgcgt ttttctcata ctaaaagcta ggttgtggga
    21481 aactggaagt tagttttaga agttactatt ttttcttagt acctgttcta gccctgctta
    21541 aactagtaaa aagaactcct acatccataa gtgacatagg agtttaggct tatcttttac
    21601 tgagttacag ttacttctcc agttcggtaa tccagttgaa gtcccttttg aacattggga
    21661 actagaacat tgaattccaa ttctccatcc gaagacttgg cttcaatctg tgaagctgag
    21721 ggaactaaat cctcgtttga agcgtagtaa agggttacac ggtaacggac acgcttgttt
    21781 tggtccaagg ctttacgcac cttgctttca tagtagtttt gaccagtcga atactcggct
    21841 tgtgcctgat ttgcccaggc tgtctgaaca gcaatgtttt taggattgct tgttgaggca
    21901 tcaaaaccat ccaaaccacc gattaaggca tagcctaaca aatgacctct atcgactgca
    21961 tgggtataag agccctttag attcttgacc tgatgccaac ctggaggagt ccaagaagtt
    22021 gaaccattcc cagtttcttt acgattcttg tactgacgag tggccttaga caagagggca
    22081 ttagctacgg ttggaacagt ttccttaccc actgtctttg ttttattgtc agcgtagggc
    22141 ttacttgaaa ccttggcatc tagatttgtt ttattaccat tgacgataaa agcacctgag
    22201 ccattccact ccagactccc ctttatttga ctcttgactg cgtctgttaa gacactctct
    22261 gccaatgctt gactaggagc ttcaggcgct tgttttttct gactaagctt ggttttagga
    22321 ctattagctg tcgactgcat ctgcttgata taatagctcc ctgtagacaa aagcaataac
    22381 actagcagtc cgattagtgt ctgtcttgtt tttttgttca tatttctcct tatctttaga
    22441 aaaaggctgg ttctccagcc taatttcctg taaatttatg aatcaattcc tgccattttg
    22501 ctggagacag gatagcccat gaatcttgac ccttgcccaa gattccataa cctaccatta
    22561 aaccgattcc tagagccaga gtacctaaaa tcagtactat gatgactaaa agtaaacgct
    22621 tgactacgta gcttgatttc ttattcatct tcatcacttg cctcaatccg ctgaatctta
    22681 gcacctagct gcgccaactt ctcatggaaa ccgtagtaac ctctatccaa gtgaaccaat
    22741 ttaccgacca cagtttctcc ctgtgctacc aaacctgtca aaatcaaagc tgcactggca
    22801 cgaaggtcag ttgaaagaac ttctgctccc tgcaaaggct gtccaccaac aatacgagct
    22861 gtatcacgga taatctcaga atgcaagccc atgcggcgca tctcttctag gtgttggaaa
    22921 cgattttcaa aaactgtctc caccatggtt gattcgcctt ttgcaactgt catcaaggct
    22981 gtaaattgag cctgcatatc tgttggaaat cctgggtggg gcaaggtttt cacatgaaca
    23041 gcttttagat tttccagttg agaacgaaca cgaattcctt cgtcttcttc aattacttca
    23101 acacccattt caagtaactt ggcaatcaag ggacggttgt gctcccagac agcgtctcga
    23161 atcaagacat caccaccagt catggcagca gctaccataa aggttcctgc ttcgatacgg
    23221 tcctggacta cattgtgagt cgtaccatga agtttctcaa caccagtaat ggttatagtc
    23281 tctgtaccag cacctttgac cttggctccc atttcattaa ggagaatggc taagtcaaca
    23341 atctcaggct cacgcgcagc attctcaatc actgtcaccc catcagccag agtcgctgcc
    23401 atcatcaagt tctgcgttgc accaacactt ggaaagtcca tatagatatg agcaccatgc
    23461 aagcgttctg cctttgcttc gatgtaacca gctgtctgac taatcttaac ccccatagct
    23521 tccagacctt tcaaatgaag atcaatagga cggctaccaa tcgtacaacc acctggcatg
    23581 gataccttgg catgacccac acgggcaagg attggcccta atacaacgat ggaggcgcgc
    23641 atcttactga catacttgta aggggcttcc tcagtgatgt cgccagtagc atccaccttg
    23701 acaagatgag cttcctcatc aaagtcaacc ttggcattca aaccaccaac tacctgattc
    23761 ataataaaga catccgacaa aatcggaaca ttctgcaaga cggtctttcc ttcacttgct
    23821 agaatagtcg ctgccaacaa gggtaagact gcattttttg ctccctcgat cgtcacgctt
    23881 cctaccagac gattatcgcc accttgaacc acaattttat ccatactcgt ttcctttact
    23941 cttgatttta taataatcct ctaagcgctt cttgccacaa atgatacagg ctaataaaga
    24001 aagaactcag gatgtagcct atgacaatgc taaaaaaggc tactaataca cgaacttttc
    24061 ttgtattctc agctgtcact tttaaaacct tttcccatct aacaagatcc tttaaaaggt
    24121 aaaaactcac ataaataaag agcatatgac tacttagagt gaataataat tgaaccattt
    24181 gactattata ccatcttctc tgtttgtgcg ctagtttgga aacttcactc aaaaattagg
    24241 gattgttttt caagtaatca atcgcatctt gtagggtttt aacgggcacg attttcatat
    24301 ccgtcttgat tgttttagcc gcttctaggg ctgtttggta gttgtttttc gcgtccggat
    24361 gcgccttttg ttcttcttcg ctaacagggt tatcaggagc aaagaaaata gcagcacctg
    24421 ccctagccga agctacaacc ttcttatcaa tacctccaat gtctcccaca ttaccatcgc
    24481 ggtcaatggt acctgtaccg gcaacaatac gaccattacg aagatctggg tgagctattt
    24541 gagtatagat agctagacta aacatgagac cagcacttgg gccgccaata ccagctgttg
    24601 aaaagctaat tgggacattg ctgattacct ctgtacgatc aatcaagccg attccaatcc
    24661 cattttttcc attttccaag gtgataatct tcccttctgc agacttggtt tgcccatcct
    24721 cttcataggt gaccttgacg gaatccccta atttttgaga actgacgtaa tcaatcaagt
    24781 ctttggaact atcaaaggtc tgatcattga ctgctgtgac tgtatcagag atattgagaa
    24841 tccctttaaa ggttgaatta tccgtcacat tcaaaacata aactccaaag tacttgagtt
    24901 cgatatcctt accagctgtt tttagtcctt gatacttggc catattttgc gatgtttgca
    24961 tgtagaattg attgattcgc ataaattcaa catcggaaga accacctgta gtctcctgag
    25021 cactacgaat atctgtaaaa ggtgtcaacc aagcataaat catatgagct aaagtagcat
    25081 gttgaacacc aaccgtaacg aattgatagg caccagcttc cttatcttct gtgtcattta
    25141 ctttaaggac ttggcgaata tcttccgaac cacctggaac ctctatataa taaggcaagg
    25201 gcactacaaa tgccaagaaa gtcacaatca aggccgcaat gacgtataag ggccatctaa
    25261 tctttttttt catttcttat ttcctccaaa atactctcgg gaacatagca ggcaatatcc
    25321 tgaccaaact tcaaaagctc tctaacgcct gatgaactga tatagagatg ttcaggtcga
    25381 ctatgtaaat aaatagtctc tatatcagaa gacagctgat gattgtagta atcaaaactg
    25441 gcttcatatt gcaaatccga cgcattcctc aaaccacgca ctagacaagt agcacccaat
    25501 ctttttgcaa catcgaccac caattcatca tgagaagcca cgacttcaac attttccaaa
    25561 tgtcccaaag ccttttctag cccccgttta cgattttcaa gagggagaaa tccttgtttg
    25621 tggggattaa aaaaaatacc cacacaaagc ttatcaaaaa gtctgctcgc ccgttcaatg
    25681 atatccagat gcccatttgt catcggatca aatgagcctg tgaataagcc aatcttatct
    25741 gacatagact gtcaccttac taattccata aatcttttcc ttccagatac ccagacaggc
    25801 aatttcttct ggaagttcaa cggtcttatc cgtctcgcac acaaccataa catcttcaga
    25861 aaaaagctct ctctcagcca ttttttcaat atctgctacg atttgttcct tggcataggg
    25921 agggtctaag aaaacgaggt caaattcccc agatacctgt tccaatgccc tttctgcatc
    25981 cattttgagg agttgaaatt ttccaacttc cttggtcatc tggatatttt cagccacgat
    26041 ggtctgagcc ttacggtctc gctccaccaa aacagcactg gacatgccac gcgatactgc
    26101 ttcgatagat aaaccaccac tacctgcata aaggtccaag actcgtccca cttcaaagta
    26161 gggaccaatc atgttaaaaa tggctcccct aaccttatcc gaagtaggtc ttgttgtctt
    26221 gccttctagt gtcttgaggg gacgtccccc atagattcct gatacgattt tcatactgtt
    26281 tattatacca aattatagac aaaaagagaa agaaaaccga accttgcggt tcgattctct
    26341 acaaaatatt ttcgtaagta tcgcggactt cttgaggcca aacacttgtt tgcacttctc
    26401 cgatgtgtct cttgcgaagt aggaacatgg ccatacgaga ttgtccaatt cctccaccga
    26461 ttgtcaatgg gaataggcca ttcaacaaag acttgtgcca ttccaattct aagcggtctt
    26521 catcacctgt aatttccacc tgacgtctaa gagtttcttc atctacacga attcccatag
    26581 aagacaactc aaaggctcca cctaaagact cattccagac aagaatatca ccatttagac
    26641 ccttgtagcc attctcagac tcgcttgtcc agtcatcata gtctggtgca cgtccatcgt
    26701 gcggtttacc atctggcaac tcgccaccga taccaatcaa aaagacggct ccaaattctt
    26761 tacaaatcgc attttcacgt tctttaggtg tcaagtctgg gtagcgttct accaattctt
    26821 ctgtatggat aaaggtgatt tgttttggca agatagactc gatgtcatag cgggcttcaa
    26881 cagctagctc agtcaggcga atagccttat aaatcttctc aactgtttct tttagataaa
    26941 cgatgttacg cttaccattt gggataacct tctcccagtc ccactggtca acataaacag
    27001 agtgggttgc atccaaggaa tcctcatctg gacgaagggc tttcatgtgg acaaagagac
    27061 cctctccttc accaaagcca aaacgagcca aggtgtggcg tttccattta gcaagtgagt
    27121 gcaccacttc ataagtagca tcagggattt ggagaacctt gaccgatact ggattttcca
    27181 caccagacag gttgtcctgc attccgtcac cgaccttact caagatagga ccttgaactt
    27241 cgacaacttc tagcttatct ttcaaatact gggtaaaagt gtttttgaca aaggaaattt
    27301 cttcttgttg atggataaaa cttttcttca tagacaactc ctcaaaaatt taataaacgt
    27361 attatacacc tatttccaag aaaagaaaag agaaaatttt aaaaaaatca gtgtcactca
    27421 aaacactgat ttcatagacc ttttagtcat tgcgaccaaa gatacgtaga atacttagga
    27481 aaagattgat aaaatcaaga tagatgctga gagccattga caccacccag cctgtcgcta
    27541 cacgaccttg tgattgttca taggcgaggc gaatcttttg gttatcccaa gcaatcaacc
    27601 ctgaaaaaac caaaaccatg gctacgctaa tcatataatc aaagaagcca ctagccaaga
    27661 aaatattgac taccatagca atcagtaaac caatgagagc tgccatcatt gctcgaccaa
    27721 tcccactcaa gtctttcttg gtaaaaatac caactgccgc catgacaaag aagagaaggg
    27781 cgctcgatac aaaggcagat aaaactgtac ccggagtata gaaagccacc acaaaactaa
    27841 gggtaaagcc gtttaaaacg gagtaaagta aaaatactgg aagagcagct ggactatttc
    27901 ttgaagccat gctactggca acgaaaacca aagccaactc cgcaaaagta gcaatggtca
    27961 accagagacg cccctgcatc aacaagtaaa ccaactgaga ctgaaagacc gtcaacataa
    28021 ggcctgatac caaagcagat agtccgattc ccagaccaac aaaggcataa accttagcgt
    28081 aaaattgatt gagacctgca cggtcatgta taatagtgtg attcatcctt ttctcctttt
    28141 ctgtgaacat ctttccttga ttataacaaa aaaagttaaa attagcttaa atggaagatt
    28201 aaaataccgg ctgcaactgc aacattcaaa ctctcggcct gccccttcat gctaatatgg
    28261 accaactggt ctgcactttc agccataagg ggactaattc cttgaccctc atttcccata
    28321 actagtacaa aattttctat agaaggcagt tctctgtaat caacagaatc tttagatagg
    28381 gttgttgcta gcactgggat agctaccttt ttagtttcgt caagaagcgc ttgactagtc
    28441 atccggtaaa tgggcagatg gaaatgacta ccttgcatgg aacgtagggt tttgagactg
    28501 tagatgtctg ccgacttatc tgaaacaatc actcctgtaa aacctgctgc atccgcagtt
    28561 cgaatgatag ttcctacatt accaggatct tgcacatctt ccaaaaacaa gaacttgccc
    28621 tgactcaaat cagcttgtcc tacttcttct ttttgaacca cggcaacaat tccctgtgga
    28681 gtctgagaat ccgccaaatc tagcaaaata tcctctgaaa tccagacagt ttgcggaaaa
    28741 gcagctaact gatttcgata attttctagg gcaaagattt tctcaatcgt cactccagct
    28801 tggacagctt cttcaaacaa gtgccagcct tcaatcaaat aggcagactt gcggtatttt
    28861 ttttggtgta atttcttggc attttttacc acagaattgg cttttgaggt tataatagtc
    28921 atagaaatat tataacacaa tcaaaggggt ttggtatgca aaaggttaga atgattgccc
    28981 aaggtagggt gcagggagtc ggctttcgtt ggggtgttta tagcctggcc cttgaaatcg
    29041 gtggcatcac aggtcgggta tggaataacg acgatggcac agtggaaatc ttagcccaag
    29101 cagactcatc tgctatcatg gcaaaattta tccaagaaat ccgaaaagga ccgacacctt
    29161 tttcaaaagt aagctactta gatgtcaaac taagcaactt tcctccctac tctgacttta
    29221 aaatcgcaaa ttaggtctcc agaactattg tatattttgt aaaaaaacag tagaatagaa
    29281 aggtataatt tttaaagaag gaataaaaac agtgaaatct attaaacgtt ttgcattctc
    29341 ggctatggga gtggctatgt tgcttgtctt gactggctgt gtcaatgtcg ataaaaccac
    29401 aggtcagcca acaggattta tttggaatac gatcggagcg cctatggctg aagccatcaa
    29461 gtacttcgct actgataaag gtctaggctt tggtgtcgct atcattatcg taaccattat
    29521 cgtacgcttg attatcttac cacttggtat ctaccaatca tggaaggcaa cgcttcactc
    29581 tgaaaagatg aacgctctca agcatgtcct tgagccacac caaacacgtc tcaaagaagc
    29641 aactactcaa gaagaaaaac tcgaagccca acaagccctc tttgccgctc aaaaagagca
    29701 cggcatcagc atgtttggtg gtgtaggatg tttccctatc ctccttcaaa tgcctttctt
    29761 ctctgctatc tactttgctg cccaacatac tgaaggggtt gctcaagcaa gctacctagg
    29821 cattcctcta ggttctccaa gtatgatttt ggttgcctgt gctggtgtcc tttactatct
    29881 tcaatcgctc ctttcacttc acggagtaga agatgaaatg caaagagaac aaatcaagaa
    29941 aatgatttac atgagcccac tcatgatcgt cgtcttctcc ctcttctcac cagctagtgt
    30001 cacactttac tgggttgtcg gtggtttcat gatgattctc caacagttta tcgtcaacta
    30061 tatcgttcgt ccaaaacttc gcaaaaaagt ccgtgaagaa ctagccaaga acccaccaaa
    30121 agcaagtgct ttctctaaac caagtggacg aaaagacgtt acccctgaac aaccaactgc
    30181 tatcacaagc aagaaaaaac acaaaaatcg caacgctgga aaacaacgtt cgagataaga
    30241 agaaaaaggc ttagctgatt tgctaagtct ttttgcaaat caaaagcccg atgtttccat
    30301 caggcttctt ttctatccat gtacacgttt catataatct tgataacttt cggtatccat
    30361 gagtttttta gcgttcttga cgcgatctgc tgttggtggt ttgactcctt cgagggaata
    30421 tggaattcca agttcacgcc acttgaactc acccatggtg tgataaggta gaatttcaaa
    30481 cttatcaaca tttttgaggg tcttgacgaa cttaccaagt tcaatcaagt catcatctct
    30541 gtctgtcaat cctggaacta gcacgtggcg aatccagaca ggttttccaa tatctgatag
    30601 atactgggca caagccaaga tatttttatt agtttggcta gtgacaatct tgtgctgttc
    30661 ttcgttgatt tccttgatat ccaaaagaac caagtcagtg acagccatga gtttgtcaaa
    30721 cttctcaagg taacgtggtt tattacggaa aggaagagca caggtatcca aggtacagtg
    30781 gattccttgt tccttagcct tggtgaagag agcaatcagg aaatcaatct gcaagagagc
    30841 ttctcctcca ctgactgtaa tcccaccctt atttccccag aaaccacggt agcgcaaggc
    30901 ctctgtcaag acatcatcta ccgtccgttc acgtgactta ttggactcca tagcccaagt
    30961 gtctgggttg tggcaatact ggcaacgcat gtgacagccc tgcaaaaaga caataaagcg
    31021 aataccaggc ccatctactg acccaaagct ttctgtcgaa tgcaccattc ctgtcacttg
    31081 tccataatca attgtttctt cagacatatc gttaccttcc ttgaaaacgt tttatagttt
    31141 tattatatca cgacttgaag gaaaaacaag atttttgcct attttttaga aagcaatctg
    31201 tttttcaatt tcattttcaa tctattatca gattattctt caaaatcgaa gccatataag
    31261 gttgcaaaat agtcctcagg gcgctctgca cggcggattt gacgggcttt accttcttcg
    31321 gtatagagga tttccgcaga acgtaatttg gcattatact ggtagcccat tgaaaatccg
    31381 tgggcacctg tatcatgaat taccagcaaa tcaccgattt ctgtatgagg cagttcgcga
    31441 ttgactgcaa atttatcatt gttttcacag agtgaaccaa ccacatctac cgcttcagct
    31501 ggtccatctg gatgggtcac gttgctaata tgatggtaag ctccgtacat agctggacgc
    31561 atgaggttga ctgctgaggc atccacacct agataggtac ggtaggtttc cttcttatga
    31621 gtcactcttg tgactagagc accgtgaggt gccagcataa aacgacccaa ttcggtgaaa
    31681 atcttgacct gaccaagacc tgctgacgta agaacttctt catacacctt acgaactccc
    31741 tcaccaatca aggcgatatc gttcggctcc tggtctggac gataattaac accaataccg
    31801 ccagaaagat tgataaagtc tagcgaaatg cccaactttt ccttgatttc aacagccagt
    31861 tcaaagagct gacgagccaa ctctggataa tagagatggg tcacggtatt ggacgctagg
    31921 aaggagtgaa tcccaaaagt cttggctcct ttttccttca agatagcaaa ggcttcaaag
    31981 agctggtcct tggtcatgcc aaacttagcc tccccaggat tgtccataat gtctgtcccc
    32041 agttcaaaaa cgcctccagg attataacga caagagatga tttctggaat gcctgctact
    32101 ctctccagat gttcaatatc ttcaaaggca tccaagttaa tggtcgcacc caattcacgt
    32161 gcataggcgt attccttgtc tggcgtgttg ttggaagaga acataatctc agaacccaga
    32221 aagtccagtt tatggctcat caaaagctct acataactag agcagtccac accacaacct
    32281 tcttcttgga gaattttcaa aatagctgga gttggagtag ccttaactgc aaaatattcc
    32341 ttaaagccct tgttccacga aaaagcttgg ttgacggctc ttgccttctc acgaatcccc
    32401 ttctcatcat acaagtgaaa gggagtcggg aactcggcaa caatcgcttc taactcttct
    32461 ctattgataa atggtgtttt cataagcttc cttctattct gtttgcaaag aaaggctggg
    32521 acaatcgttc caacctttag ttctatctct tatttatctt cgtcaaagat attgccaacc
    32581 tcaacatcga tggcttggtt cttgacatca atattggtta ccttcaagag tgacttgtag
    32641 tcaaactgct tttcacgttc ttcttgggca ttgtccgcaa agaccgctac acctgccagt
    32701 tctgagtcga actcgtgcaa gagactaatc ataccattga ccgttccgcc acctttcaag
    32761 aagtcatcca caatcaagac acggctgcct gccttaagac tacgttttga aaggaacatt
    32821 ttctcgatac ggtcaccact tgaacctgaa acatagttga cgctaacagt tgaaccttcg
    32881 gtaattttca ggtcacggcg cacaatgaca aaagagacat tgaggacatt ggcaactgca
    32941 tttgcaagtg gcacaccctt agttgctacg gtcataaccg cgtcaatttt ttggtccata
    33001 aagcttttgg caataatacg accaatattt ttcaagatgg ctggtgtgct aagcaaatca
    33061 gacagataga tataaccacc tggcaagata cggtcacttt ctgacaactt ggtacgcaag
    33121 tcttcaacca tttccttagc atcctgactc gaaatagacg gtgtgaagat gacacctccg
    33181 ccagccccag tcactgtctg gatatgaccg atttcaattt cctcaaaggc gcgtttgata
    33241 atgacgatat cttctgagat ggatgattta gcagactcat acttttcagc aaaagtattg
    33301 agactagtta gtttataagg attattaatc aaatagttgg aaatgacaac catccgatca
    33361 cttcttctta atttcatttc tatttcctat tccattttta ttcaaaaaat caaaaagcaa
    33421 actagaaagc tggtcgctgg tggttcaaaa cactgttttg agattgtcaa tagaactgac
    33481 aaaccctgta atatacctgc atatatacat acgacaaggc gatactaccc tagtttgaag
    33541 agattttcga agagtattca tttttgtctt ttacttatta taccatattc acataaaaaa
    33601 acgaacattc ttatcctaaa aaatgctcat ttttcttaaa ttatcaatct aaatctggtt
    33661 tatagaagga acgattatcc atagcgaaga ttttattggt catctctcct ttatccacca
    33721 aagccagagc tgttgacatc atcatcatgc ttgcatccag attgtcaatc atatggataa
    33781 tctctgcctc cataatacgt ggacggactg gacttccata ttcaagcaag ccgtggtgac
    33841 tgaggatgac atgacgaagc aaaacgactt cttccttggt atcatcgatg ccgagttcca
    33901 taactgtctt ggtaatttcg ctatcaatga gagcgatatg tccaagaaga ttacctcgca
    33961 ctgtgtactc tgtctggtct ggccccgtca actcgataac cttagctaag tcatgcagca
    34021 taatccccgc atagagcagg ctcttattga gctgaggata aacttcgcta atagcgtctg
    34081 ccaaacgtac catggtcgcc gtatgataag ccaaccccgt ttcaaaggca tggtggttgg
    34141 tcttggcagc tggataggag tagaattcct tatcatactt ggtgtagaga tttcggacaa
    34201 tccgttgcca gacaggattt tcaattttga aaatcatttg cgacatgtag tcacgaattt
    34261 ccttgacatc aactggtgac ttgaccttga aatcggctgg gtcattgggt tcaccagctt
    34321 gaggcaggcg gagagtaatt tgattgactt gaggggtatt gttataaact tctcggcgtc
    34381 ctttcatgtg gacaacctta cctgcggtaa aggcctcaat gttatgaggt tgggcatccc
    34441 agagcttccc atcaatctcg ccactatcat cttggaaggt aaaggctagg tagtttttcc
    34501 cagctcgagt ttgcctcagg tcagctgatt tgattaggta aaagccttca aatagctcat
    34561 cttttttcat gtgactaatc ttcatattct tcctcatttt cttgaaaatg gagtagatca
    34621 agcgcaggct caccttctga caactcaatg tgacggagcg tccgctcgat agctatggta
    34681 cgacggttta ataattcatc aatattgcca gaggcatgtt ggagatgttt ttgtgccttg
    34741 accagaatac caccaaactt gccaaactcg gtcttgacac tggcaagagt cttgctgata
    34801 tggtcggcac tcttttggat attaagggtc ttgaaaccaa ctgatagaga gttaagaagg
    34861 gctgataggg tacttggtcc tgcaacaata atctgttctt cccgtctcaa atcatcaaag
    34921 aagaccggat tgcgcacaat ctctgaataa agaccttctg tcggaacaaa caagattcca
    34981 aagttggttg tccgaggtgg tgctatgtac ttgttcctaa tatccctagc aaagcgcttg
    35041 acgcttgcta ggagtgactt acgacagcgt tcaatctcat ccttgtcacc tgtctcatag
    35101 gcttcttcca agcggtaata atctgccagt ggaaacttag agtcaattgg cagatagacg
    35161 tattcttggt cgccttgtcc gggtaacttg atggcatact ccactcgttc actagagttt
    35221 tcaaccgttg cgtattctcg ttcgtactgg gcaggtgtca tgatgtcttc aataatttgc
    35281 cccagttgca attctcccag aatccctcgc gtcttggttc cagagagaac cttgttaaga
    35341 gctccgacat cacgggcaac tgtctgcatt tctccaaggc cacgattgac agactccagt
    35401 tgtttagaaa ctgtctcaaa ggaagcctgt aagcgtgtct gcaaggtctt ttctagtttt
    35461 tcctcgaccg tctggcgcat ttgttccaaa cgttgctcat ttgattcctg caaggcttgg
    35521 agacgttggt ctgtcttgtc tctagtttgg aggagattat ctgtcatttc ttgacggact
    35581 tgggtcagac cttggtgcaa ttcaatccgc acttcttgca aacggtcgct gacaaccact
    35641 tccaaatctt tttggtctaa ctggctggct tgtctggctt ggtcaaagcg gtaatccaac
    35701 tggtctgaca aatgatctgc ctgatcctcc aagctcttac ttaagtgttt ctcctgccta
    35761 tcctgccttt gccaaatcag aaagagacca gctagattgg caattaataa tagaataagt
    35821 aaactttcca tcctacctcc tgtccttgct atgcagtacg accacataac catctgggca
    35881 agttaccgac acttccctat ctatatattc gttagaagcg tacacttttt taaagaaaaa
    35941 attttcctct gtcaactcat acttggctcc aagaatagtc agctggctat cccgaactgg
    36001 cataaaggct agatagtcgt agtctgaacg aggttctagc tgactgattc cttctggaca
    36061 ataagtaatc aagttttgcc catcctcaat ttctatttga tgcatatagg atgccaactt
    36121 aggattgcta ggcagaaaga cattggccaa catatggtca atacggccac ccaaggcacc
    36181 gaaaatagta acctgagcct gaggattttg cttaaagatg gtcaagagag ccaattccaa
    36241 atcagtatca tctttttctg gccgggcttg gacaaaatac tgggcacgtt tttgaatcac
    36301 ctgtcgctct tcttccgtca cagaatcaaa atctccgact gctagagcaa gaggcaaatc
    36361 ttcttccaag atccagagcg agcctcgatc cacaccaaca aaaccatcaa agtccgtccg
    36421 ataatgaccg cggtctccgc ctgcaaaaac ggcaacccta gtccagttgt tttctgagag
    36481 tttgtactcg ctcattgaca tctcccttaa agacatagga acctgctaca aaaacggtcg
    36541 caccagcttc tttggcttga gcaatagttt ggtcatcaat cccaccatcc acttcaatct
    36601 caaagttcaa acctttttca tcacgaaggg caaccagctc acgaacctta tccatggttt
    36661 ctggcagaaa ggcttgacca ccaaatccag ggttaactgt catgactagg acttggtcaa
    36721 ctagatgaag cacatgctta atcgcttcaa ctggtgtacc aggattgata acaactgatg
    36781 gcttgacacc gagtgaacga atcttttgga gggcaccatg aatatgaggc gttgcttcca
    36841 catggatact aataatatcc gcacctgcac gcacaaagtc ctctaaatga tgctcagggt
    36901 ttgacaccat caagtggcag tcgaaaacca tcttactatg aggacgaaga gcttcgacca
    36961 cacccgcacc aaaactgatt tgcggcacaa aatgaccatc cataatatcg atatgggcat
    37021 actctgcccc agttgcttct aggcgtttaa tttcacgttc aaagttggca taatctgctg
    37081 ccagaattga cggagcaatc ttgtattgag acataggttt ctccttattt tggaattttt
    37141 ttgctgactt ttttataggt ttctctgcga ttttcaattt cgctgaggaa ttgcaggtag
    37201 ttgtcaaaac ggaagggcgc aatggtacct tcttcaactg ctggcttgac agcacaggac
    37261 ggctcatggg tatgggtaca agtacggaat ttgcagtctc gactgacagt ggcaatctct
    37321 ggaaaggcct gattgaggtc ttcagccgtt gatacttcat aatccagtga tgaaaagcct
    37381 ggtgtgtctg cgattttacc cccattgagg ttgtaaaaac taacagctcg agtggtatga
    37441 cgcccgcgac ccagactgtc tgaaatttct cccgtttcaa gattaagatc tggtgcgatt
    37501 ttattgagaa gagttgattt cccaacaccc gtctgcccca taaagaccgt aaccttgcct
    37561 gttaacaaag gcaggagttc ctctttactg gtcacaaagt catatccgat gtcaccatag
    37621 gtctgctggt aaaaatccag ttctcccccg tcttccaaca aatccatttt agaaatatag
    37681 acgatgggat gaataccctt atgctccaaa agaaccaaga aacgatccag caaattgctg
    37741 ttaaaatcag gttccttgac agacatgatt actacagctt ggtcgatatt gacaataggc
    37801 ggacggacca gactgttttt ccgttcgtga atcttgagaa tatagccttc tgaattttcc
    37861 tcggcagaga aatctaccca gtccccaacg taaggggtat gccctttttt acggaaattc
    37921 ccacgcgcgc gtgtttgata gacttggcca tcactctcta catagtagaa cccagccaag
    37981 gctttaatga tttgtccctg caaaataact cctttaaaat tgttagttcc attataacaa
    38041 aaaaaagcta ttttagctta gcttctcttt acaatttcga taagtctatt ctaaaagaaa
    38101 aagatacact cacgctttag ataccaagtt ttatacaaaa ataacgaatc tacctcctta
    38161 tataaaaaca ggcgaacaga gagcctaaaa ctccctgttc gctttacttt ttctgtgtgt
    38221 aatagaaaaa acctaataaa gcaagacaaa aaatatgaat ataaactcca tacatcatgt
    38281 ggggaaagac agactctata aaatagcctg gtagatagat gattggaaat tgatagaaat
    38341 cataggtcgt tagagatagt aaacaaagaa catacataaa tactgctaca attagaaccc
    38401 atccttgctt tcgccataga aaaatcatca ataagaacag acaaagtaga tagattgacc
    38461 aatttcgcaa cataaattga aaaccataaa tcatactttc agtcgtttct ccatcaatca
    38521 catcaactac tttatagaaa ggtaaacaat agctcactaa aaaaagaagg ggactaatta
    38581 tttttttcat attctctacc atggattatt ttgcaagtaa gctgaccatc tatctccata
    38641 tcgaatcaaa ttaacagtat aattagttac tacccgattt tcacctggtc caaccttaga
    38701 aaaacctgtg ctatactccc aactacttct tgcacctgga tgaaaccatt tttgctggga
    38761 tgaataccaa ccaccttgtc taacttccac acttgaagat tctatttcga tatccctttc
    38821 atggaagtca actcctccac ttattttagt aatatttttt tgtacacctc catcataact
    38881 cacccagtga acaacagtat acaattccac actataagta ctatcaaact gactttgatg
    38941 agtagtaatg ttttgagtat aagcgtgcac tttctgtata ccaaaaatat ggtctaatat
    39001 attcgttggt ttagcaagct tattgtaacc ctcttcaaca aaagtagcct tctctaaatc
    39061 agcggtataa acagtttttc cttgtactac ttgattgttt atagaagtaa tacggctatc
    39121 cacaacaatg ggggccacca tatctccatc gctagtttct attttagctg cctctttcac
    39181 ctcatataca actcgatttt cttcagactg aatcacttct accccatttt tttcaggtat
    39241 agataatcta gtttgcccat tagaaaccgt tatatttgga ccaatattct tctcatttgc
    39301 ataagtcgca ataggaaatc ctgatagaac cactgcacac ataaggctat tgactaattt
    39361 ttttctcatg aatatatcct tcccattttc aagaggagta aaaatagcta atataagatg
    39421 aacgtttcct tatatttcag aataggatat ctatctgaaa gcaattcaca ctcctataga
    39481 taactgttcc aaatcttggc tacatatatt tcaatagttt gctacaaaaa actcctttct
    39541 aagtctattg aacatgccct tattcaccta ctaatatatc acaaaaataa ataaatacaa
    39601 gactgttttt tctactagtt ttatgataga atagtattgt tagggtaaat ttcatatata
    39661 aatgtcgagt gaaaaatcga tggagcagaa atcggtagac aaagactcga tttcgttggt
    39721 ccagccccac aaggctaatc aggtatttca cgagtttaaa aatctaatga agtgcccaat
    39781 caactactga ttcattgatt taatacgaac tatagtggat tgaacctaga aatagtacac
    39841 taaggattct aaaacgtttc tagaaattaa tttgactttc ctaatctctt tgttcatatc
    39901 ttatttcaat ctactatata taccaaaatg ctaggacaaa agtctttaaa atcagagaaa
    39961 cgcatattat caggtgttgg aaaaccttga taatatgcgt tttatcatag aaagatctac
    40021 ttcatttttt actaaaatta agtttttgtc cctgcatctt agagtccttg ccctttaagt
    40081 gcatctgcta ggctggcaaa ctcttccaag ctgagagctt ccccacgcac acttggtgac
    40141 aagcctgctt ggtccaaagc cttggtcagc ttgtccttga cctcttcagt cttgccaaag
    40201 taacctgtca agttattcca caaggtcttg cggcgatggg taaaactagc cttggaaacc
    40261 ttaaagaaaa agttctcgtc ttccactgct acagctggca ctggacggcg caccattttc
    40321 aagatggctg agtctacatt tggtgctggc acaaagactg tacgcggcac gataaaggca
    40381 accttggctg tcatgtaata ctgcacagcg atagacaagc taccgtaagc cttggtattt
    40441 ggttgagccg agatacggtc cgccacttct ttttgcatca tgaccacaaa ctcactaaaa
    40501 ggaatgccac tctcgattaa gtgcatgaga ataggcgttg tgatgtagta aggcaaatta
    40561 gccactacct tgattggcag gtcaggattt ttgaaattct ggatatgttg cgccaaatcg
    40621 accttgagaa tgtcctcgtt gactacagtc acattgtcaa aatcacgcaa ggtatctgcc
    40681 aaaatcggta ccaaacgatg gtcgatctca aaggccataa cttctgctgc acgctcagcc
    40741 aaaaactcgg tcaaggcacc aatacctggc ccgatttcaa tgacattgac ctggtcatca
    40801 atctcagccg tatccacgat tttttgtagg atattggtat ccgtcaagaa attttgccca
    40861 aaggactttt taaaggtaaa accgtgacgc tccagcactg ccttggtcac gctataatct
    40921 gcaattctca tctattctct tttctattat ctgttactac tattgtaaca cattcccctt
    40981 gtattttggg ggtgaaaatc ataccaaaaa actatctttc ctcatgaaga aagatagtct
    41041 tggaaatctt taaaagtggc cttagcgctt ctctcgaaac atacgttcat actcttcgaa
    41101 aatctcttca aaccacgtca gcttcacctt gccgtactca agtacagcct gcggctagct
    41161 tcctagtttg ctctttgatt ttcattgagt atcaaaaaaa tcagcttctt gataacttcg
    41221 attttcgggt agggtcaaat ccacatcctc ctccacatca tccactgtca gttcaaccgt
    41281 ttgaggtaaa tttttcaaac gataatgctt ttgcctttgc ccttcactac tagcaaaatc
    41341 aagcaaatag ccatgcactc ggatttgaac caaaaggaga ggattggtca tattttccat
    41401 gatgaggata tcttataaac cacctctggc actaggataa tcagataccc tgcgaatacg
    41461 gattttttca cacatgagca agtttcctca tatcaatgat ttcatcagcc ttattccaga
    41521 ctaggggatt atgggtcgca atgatgataa ttcgattttc atctttcaaa tccaccaaga
    41581 gattcataac ctcctctgaa ttttcaggat caagagctgc tgttggttca tctgccaaaa
    41641 tcaagggtgg atttttcaaa atagttttcg caagggcaac tcgttgggcc tctcccccag
    41701 ataaagtata aattttttgt tctaaatcca aataccctag attaactttt tctaaagccc
    41761 ccacttgcct ttccaaacgt tctacttttg agattttctg accaacaaaa cccaaatcca
    41821 aattttcttt gattgattgg ttttctaaga ggccaaaatt ttgaaagaga tagcccatct
    41881 gatctcgaaa atactcacga gtgggaatgg tttttaaatc tttcccctga tagagaaccc
    41941 ttcctccatc tatcttttct agctttccca agatattcag cagcgtcgtc tttccgcttc
    42001 cactctttcc gattaaggca taaaccttgc ccttctccag cttgagattc aaaccagaga
    42061 aaatcgcgcg gtcattaaat ttcttttcca atccttgaat atcaatcatc ttattttcct
    42121 ttcaatactg ccatgctacc agcttcttct tttttgtcct gccttactaa aatcaagagg
    42181 gcgttaagcg taaacaaagc tacaactaga gcgctaatca aaccatctct tgtcaaaata
    42241 ctagatagga ctaggccaag caagagaact cctccttgcg ccagtaaata cttgccatga
    42301 agctcataga ttgtcatacc agcaagacgt ttaatcataa gctcccgtct gaactgctca
    42361 aaatagagaa gattcatgga atcaaataac aagatagccg tagacagggt caaaatcgtc
    42421 ccaataagga gagagtaaaa ctctacccgt ttgtcattta gtaccttggc aaaaaatagc
    42481 tggcttttta ccaagtaaga aaccttgtga tacagacctt gctcttttag agctgtgatg
    42541 ctgtctccat atcgatctag tttcaaggca ctattagccg tagttcccca caacatccct
    42601 gcaacaggtc ttgttccagt cgcttgcggc gttagaacta caataatcgg atcttttagg
    42661 tactggcgtg ttgtcttgta cccatcatta tagaggaaac gttcctgtcc tgtttctgta
    42721 aaagctagac ttacctgtgg gaggtagtat ttctgactcg tcacttctac actttcagat
    42781 gaaaagtttt gcaggtaatc tgtaaacaat ctttggtagt aggtagactg ctctcgcaag
    42841 ctctcaggca agattagccc aaactctccc tcagacaagt tttgcatctt gtccataaac
    42901 tctgaagaaa cggtaatctt ttcttctatc agatagcgtg gtgagacata gataacattc
    42961 cctgacggtg tgtagtcact gagacgattg ccatctaggt ccacttctgc tccgtctgag
    43021 aaattgtcaa cattgctcat aatataaaaa gagtctgtat tggctaaccg ttcttcagta
    43081 aatgtctgcc actcacgatt atccttacgc gttccttctt catcggcaaa tgcactagac
    43141 caaccaaagg atagacggta acggtctgag gactggctcc atttattgct agctctctcc
    43201 atttcctgca tttcacggta gtggggtagg agagctgtcg cactcgatcc gaccaccaat
    43261 acagctaaga gttgccccac catcatcaat gtcatcatac gtttgagagg gagtttccct
    43321 ttcaatagat ccaccagact attttcctgt aaaccaagta gatagacgac acttagtaag
    43381 gtagaaatcc ctgccagggt caatccataa agtagaagag caatgatgac cagttgcacc
    43441 gttgccataa acaaggcacc ttgataccag agaatcccca atcccaaaag actggatacc
    43501 agcactgagc agataaactg tctcacatct tctaacactg gtctgagagc aactccaaac
    43561 aagctctcac cagctattaa gcgaatccct gcctgacgaa gggatttgat ccgataaatc
    43621 agggtcagac tcataaaggt cagcagaaaa atagctaaac tcagtagcac cataggggtg
    43681 gccgccaata gtaagactat cgaaaatgga tcttctccat tcgaaacaaa gccttgatag
    43741 ccaagttctt tcaaggtggt ctgtaagctc actccatcca aacttcctga cacaatcaag
    43801 taagacccta ataaatcact cgtttctgca ctctccttgg aggaaatggt cagaccttct
    43861 ggaagctctc cctcaccata agtggcatag gtaaagagtg tttctccagc ttcatttggc
    43921 tcaacgattc gacgggcgat gagactatta tgctctaccg ccaagtgact caaaacctct
    43981 gtcacctctt cgcgactagc tactggttga tttatcatca ttcctgtcac atcaacagaa
    44041 ggatagttac caaataaaat ctcttctcga tggtcaacgg aagttatcac catataaagc
    44101 gataccaata ccattgaaat caaaataaat aaacgtttca tcatttcctc caaaaagtta
    44161 cttggtcact tagtgagaag gtgaccacag tcactgcgat gttaagaagc ttattaagtt
    44221 ctttctacta gcaacatctt caaatacatt atatccgttt tttcaagaac tatcaaggac
    44281 atcaatgtcc ttaaaatcta actatttcat attattttta gcttatatct aaaaaaacag
    44341 ttctaaagac gaactttaga actgttttga tacgaggaca aggacatttt tgtcactgat
    44401 tcactatgtt tataaatatt ttttgacatc ctcttgccat tcctctgtca atttctttac
    44461 tagaaatcca tctccaatta gcttcgcaaa tgttttagaa gactgataaa atgattcagc
    44521 taaactaaaa tctctttctt ctcttaatgc ttgcttccac aaaaacataa atacaagagg
    44581 tttcttttga taatcttgag ttttatccat aatttcttgt aaacacgata gataatcatt
    44641 aaaacaatca gttactccta ccttttcaag acaacacatt cctgaaataa gagtatctct
    44701 aattataaag aagttttcta atttagttac ctttttctgt tccaaaagaa agagcattag
    44761 cttttcgatt tgatttataa atttggcaag atcttttcta atgagcattt gataaaaaaa
    44821 caaacgaatc aacaacatat catttgttga ataaacttct ttttctatga tctgagacat
    44881 atgttcctca agtattaact ctgcatattc aggccttcta gttctagaag tatccaaaca
    44941 cgcctgcaat acttcacatg ctaattgttc ttctttagga agattatcaa agtatgtttt
    45001 ataaatctct tccaaacacg cttccttctt atcgtactcc tcttctttac catagattgg
    45061 ttcacgtaaa atctggtatt tcaattctaa ataagcagga ggaagagctg aaaaatccgg
    45121 cataaggcta taaactggaa ctcctagccg gcgagcaata taggctaact tgggcaaact
    45181 cggttgcgaa gctccacttt caattcgcga cagttgacga actgtcagtt cttgctcatc
    45241 tccacaaaaa tatggacgac taactccttt ttctatccga atctctttaa ttttttgacc
    45301 aattaacatc agacgcctcc tcttctacct gcttcgaaaa atactgtgaa acttaaaaaa
    45361 ttgtaacggc tacatctttc ctactcataa gatttcatag cttcttccac ttctgccaaa
    45421 gtaaccccaa acaactctag gcgtttgagg agttgcttgc cgttagaata gccgattcgg
    45481 agagtctctc cgagatattc tctacgctta cggctgtctg cccctgctag aaaaccaagg
    45541 cgaatcaagt cgctacgact aatgtcaaac tgactctcat gttcaaattg ttctgtcacc
    45601 tgagctagag ccgttttcag gtcttcatag ctggcatgct caattcccag agaacgcccc
    45661 ttggtcttgg actttggaac agcttcatct cgcttgagaa aggcatgccg aactgttgga
    45721 atggccgtca taatcatgcg ccgaatccgc tccccattaa aatctgggtc tgtaaagaca
    45781 atgactccct gacgttggtg caggcgctga atccgctcta tatcctgagc attgatggca
    45841 gaacctcgag tctcataggt ctccacatcg aaataacgtt tgagattgac cgtatcatca
    45901 cgcccttcaa ccacgataac ttgagaaatt ttctctttca ttacttgctg tccaatccaa
    45961 aaatgcgttc tgcatttgca gtcgttgcta ccgccagctc ttctgtcgtc ataccacgca
    46021 agtcagcgat aaagtcgacc acatagcgag tataggctgt tttattttca cgaccacgct
    46081 tgggtacagg tgctaagtaa ggcgcatctg tttccaccaa aatcttgtcc aaaggtaact
    46141 ctttagctgc ttcttggagg tcagttacct tcttaaaagt caccactcct gagaaggaaa
    46201 tggtcatacc aagatccaca aacttctctg cccactcaag cgtccctgaa aatgaatgca
    46261 tgataccacc acgaggacca acgccctcac tcttgataat ctcataggta tcttccagcg
    46321 catcacgggt atggacaaca aaaggcaaat ccaagtcctt agatagctga atctgacggc
    46381 gaaaaacctg ctcctgcacc tctttgggcg ctgtcatcca atggtaatct aagccaattt
    46441 cacctaaagc cacaaccttg ggatgtttta acttatccaa caagtaagcc tcaacttcct
    46501 ctgtataagt accagcttct gtaggatgcc aaccaatagt cgcatagagc tgatcatact
    46561 catctaccaa ctccaaggca cgctcaatcg tcggtttatc aaaaccaaca atattcatct
    46621 gtgtcacacc catctcagca gccaaggcaa tttcttctgc ctcacgacct gcaaattctt
    46681 ctacattcaa gtgtgtatgt gtatcaaaaa tcatctcttc taacctcgtt ttctatcttc
    46741 tattatacca aaaaagagga ggggcaccta atttttcggt ttcccctcct ctcttcaata
    46801 gagagctatt ctgctatctt ttctatccga tattgcccat ctcctattcc acagttagag
    46861 acagaagaga ttggctacat tgatagaata ttcctattca gctaaagtat gtgattatct
    46921 tgggttctca cttttctcac ccatcactag gattgatgac ttctcaaaat cccccttata
    46981 atctaacttt aagtagagaa tagaattttc tagctgttct attttctacg tctagtcttt
    47041 cttcctagca aagcaaaacc acttgttgcc accactagac caagactagc aagtgctgca
    47101 cttgatgctg aacctgtgtt aggtaattgt ttgccagcag gtgactggta ggtaacatct
    47161 tgcattgttc ctgcagttgc ttgcggtgca cttgttgtct taggagcagc attaggagcc
    47221 actggtctct taggaactgt aaccatgaca atggcttgca ctccaatcgt ttctgcttcc
    47281 ttcacatctt ccatagtttt cgcattttca atctctttga gagctgcttg tttttctgct
    47341 tccactcttg ctaaaagttc tgctttttct ttatcagaaa gcggtgcgcc tttgatttca
    47401 tcctgcttgt ccttggctgc tttttcaatg gcatttttag ctgattcttt ttcagtagct
    47461 aattgcttag aagcttgtga ttgagctgag ttttgtgaac ctgtgtgagc tgatccaccc
    47521 gcctggctac caccgcctgc attcgcatta gcatctgagc ttccagtatt gcctccctta
    47581 tctccacctg gtgtattttc tagcttatac tctggtgtag cttcttgagt tacagattca
    47641 cctttcgcag attgttgaac tgtatctttt cctagaatcg tcactactga accatctggg
    47701 aatgtgattg ttgctgtacc atctccagct acattgattg tcgctccgtc taatgctgaa
    47761 ccatttgctt gtaaaatagc aaccttaact ttttcttcat ctgttaaatg agttatatct
    47821 tttacatcta ctctttgagc aggtgcttta acagttgatt tttcagcagt cggtttagtg
    47881 ctatcttgtg cttttggatc ttgtgctacc aattgatttc ctggaattgt aatagctgaa
    47941 ccatctttaa agacgattgt cgctgcgcca tctccagcta cttcaacttt atagtaaaat
    48001 gaaataataa caggacaaat cgatcaggac agtcaaatcg atttctaaca atgttttaga
    48061 aatagaggtg tactattcta gtttcaatct actataacat cgcttccgaa tccatttgca
    48121 tctactgaac ttttttacaa aaataaaaat cagtagactc gagttcctac tgatttttga
    48181 tagaattcgt ttggattatg cagccaaaac tttgcgtcct ttacgacgac gagctgccaa
    48241 tacgcgacga ccatttttag ttgacatacg gttacggaat ccgtgtttgc gcgcacgacg
    48301 aagtttactt ggttgataag tacgtttcac gatgaatacc tcctcataga ttttgtattc
    48361 gtttagccgg ctataaagtg atcagttact aaacatactt tactattcta tctgattctt
    48421 tcacttttgt caatagctct aggcaaatgt ttccagcttt ttcgaatgca agcc
//
LOCUS       DAVAZT010000008        46483 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVAZT010000008 DAVAZT010000000
VERSION     DAVAZT010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46483
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.008"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..334
                     /locus_tag="VQT45_000410"
     CDS             <1..334
                     /locus_tag="VQT45_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET2358794.1"
                     /translation="QAFKEKHYENTILHSDQGWQYQHDSYHQFLESKGIQASMSRKGN
                     SPDNGMMESFFGILKSEMFYGYEKSFQSLKQLEQAIIDYIDYYNNKRIKIKLKGLSPV
                     QYRTKSFG"
     gene            complement(379..1020)
                     /gene="plsY"
                     /locus_tag="VQT45_000411"
     CDS             complement(379..1020)
                     /gene="plsY"
                     /locus_tag="VQT45_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HET2358795.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            1156..3099
                     /gene="parE"
                     /locus_tag="VQT45_000412"
     CDS             1156..3099
                     /gene="parE"
                     /locus_tag="VQT45_000412"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HET2358796.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            3519..5990
                     /gene="parC"
                     /locus_tag="VQT45_000413"
     CDS             3519..5990
                     /gene="parC"
                     /locus_tag="VQT45_000413"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HET2358797.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            6122..7144
                     /locus_tag="VQT45_000414"
     CDS             6122..7144
                     /locus_tag="VQT45_000414"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HET2358798.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            7200..7904
                     /locus_tag="VQT45_000415"
     CDS             7200..7904
                     /locus_tag="VQT45_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2358799.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSDM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGFPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            7969..8658
                     /locus_tag="VQT45_000416"
     CDS             7969..8658
                     /locus_tag="VQT45_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HET2358800.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            8655..9578
                     /locus_tag="VQT45_000417"
     CDS             8655..9578
                     /locus_tag="VQT45_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HET2358801.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            9593..10237
                     /gene="pcp"
                     /locus_tag="VQT45_000418"
     CDS             9593..10237
                     /gene="pcp"
                     /locus_tag="VQT45_000418"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET2358802.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            10405..10635
                     /locus_tag="VQT45_000419"
     CDS             10405..10635
                     /locus_tag="VQT45_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HET2358803.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            10685..10765
                     /locus_tag="VQT45_000420"
     tRNA            10685..10765
                     /locus_tag="VQT45_000420"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10719..10721,aa:Tyr,seq:gta)
     gene            10775..10846
                     /locus_tag="VQT45_000421"
     tRNA            10775..10846
                     /locus_tag="VQT45_000421"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10807..10809,aa:Gln,seq:ttg)
     gene            11008..12210
                     /gene="rpsA"
                     /locus_tag="VQT45_000422"
     CDS             11008..12210
                     /gene="rpsA"
                     /locus_tag="VQT45_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HET2358804.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            12296..12793
                     /locus_tag="VQT45_000423"
     CDS             12296..12793
                     /locus_tag="VQT45_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HET2358805.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            12793..14448
                     /gene="dnaX"
                     /locus_tag="VQT45_000424"
     CDS             12793..14448
                     /gene="dnaX"
                     /locus_tag="VQT45_000424"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HET2358806.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            14476..14670
                     /locus_tag="VQT45_000425"
     CDS             14476..14670
                     /locus_tag="VQT45_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HET2358807.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            14820..15590
                     /gene="sufC"
                     /locus_tag="VQT45_000426"
     CDS             14820..15590
                     /gene="sufC"
                     /locus_tag="VQT45_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HET2358808.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITRLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            15618..16880
                     /gene="sufD"
                     /locus_tag="VQT45_000427"
     CDS             15618..16880
                     /gene="sufD"
                     /locus_tag="VQT45_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HET2358809.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKINYLERLESRGEGSAKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSYADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            16891..18117
                     /locus_tag="VQT45_000428"
     CDS             16891..18117
                     /locus_tag="VQT45_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET2358810.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPASARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            18104..18544
                     /locus_tag="VQT45_000429"
     CDS             18104..18544
                     /locus_tag="VQT45_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HET2358811.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            18594..20006
                     /gene="sufB"
                     /locus_tag="VQT45_000430"
     CDS             18594..20006
                     /gene="sufB"
                     /locus_tag="VQT45_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HET2358812.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(20237..21478)
                     /locus_tag="VQT45_000431"
     CDS             complement(20237..21478)
                     /locus_tag="VQT45_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HET2358813.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITAYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFIDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            21581..22690
                     /locus_tag="VQT45_000432"
     CDS             21581..22690
                     /locus_tag="VQT45_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET2358814.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            23224..23571
                     /gene="ssrA"
                     /locus_tag="VQT45_000433"
     tmRNA           23224..23571
                     /gene="ssrA"
                     /locus_tag="VQT45_000433"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(23754..23841)
                     /locus_tag="VQT45_000434"
     tRNA            complement(23754..23841)
                     /locus_tag="VQT45_000434"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(23805..23807),aa:Ser,seq:gga)
     gene            24003..24743
                     /locus_tag="VQT45_000435"
     CDS             24003..24743
                     /locus_tag="VQT45_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2358815.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNITVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            24740..25651
                     /gene="pfkB"
                     /locus_tag="VQT45_000436"
     CDS             24740..25651
                     /gene="pfkB"
                     /locus_tag="VQT45_000436"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HET2358816.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDVVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            25648..27600
                     /locus_tag="VQT45_000437"
     CDS             25648..27600
                     /locus_tag="VQT45_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2358817.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTDHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            27764..29989
                     /locus_tag="VQT45_000438"
     CDS             27764..29989
                     /locus_tag="VQT45_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HET2358818.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(30034..30462)
                     /locus_tag="VQT45_000439"
     CDS             complement(30034..30462)
                     /locus_tag="VQT45_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2358819.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQSNAPTSENKSNQ"
     gene            30600..31742
                     /locus_tag="VQT45_000440"
     CDS             30600..31742
                     /locus_tag="VQT45_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET2358820.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWLIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGLVDVEALAGLIRHDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDCATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     NYPDIFVFSDEENFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            31751..32965
                     /gene="thiI"
                     /locus_tag="VQT45_000441"
     CDS             31751..32965
                     /gene="thiI"
                     /locus_tag="VQT45_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HET2358821.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYTQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            33100..33924
                     /locus_tag="VQT45_000442"
     CDS             33100..33924
                     /locus_tag="VQT45_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2358822.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPGQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYFECQKLSPDQRIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            33946..34685
                     /locus_tag="VQT45_000443"
                     /pseudo
     CDS             33946..34685
                     /locus_tag="VQT45_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            34698..35864
                     /locus_tag="VQT45_000444"
     CDS             34698..35864
                     /locus_tag="VQT45_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET2358823.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIGRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMEQMIADFGQRQE"
     gene            36372..37865
                     /locus_tag="VQT45_000445"
     CDS             36372..37865
                     /locus_tag="VQT45_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET2358824.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            37878..38924
                     /locus_tag="VQT45_000446"
     CDS             37878..38924
                     /locus_tag="VQT45_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2358825.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     LQLDELNLLVKSRFNEMFGDVILNEKEWKVSKWNEILTIRNGKNQKQVEDADGKFPIY
                     GSGGIMGYAKDWIVKKNSVIIGRKGNINKPILVRENFWNVDTAFGLEPVLEKINSEYL
                     FYFCQLYNFEKLNKAVTIPSLTKSDLLNISIPLPPLALQNEFADFVALVDKSQFACEI
                     AIKVWRNSLKFSII"
     gene            38954..41650
                     /locus_tag="VQT45_000447"
                     /pseudo
     CDS             38954..41650
                     /locus_tag="VQT45_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            complement(41684..42940)
                     /locus_tag="VQT45_000448"
     CDS             complement(41684..42940)
                     /locus_tag="VQT45_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET2358826.1"
                     /translation="MEQLHFITKLLDIKDTNIQIIDVVNRDSHKEIIAKLDYDAPSCP
                     ECGNQLKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYA
                     FTKGKMSFIAQDFDNLNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYD
                     LAKQLFPCAKIVLDRFHIIQHLSRAMSRFRVQIMNQFERKSHEYKAIKRYWKLIQQDS
                     RKLSDKRFYRPTFRMHLTNKEILDKILSYSEDLKHHYQIYQLLLFHFQNKDPEKFFGL
                     IEDNLKQVHPLFQTVFKTFLKNKEKIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRN
                     FENFKKRIFIALNIKKERTKFVLSQA"
     gene            43026..43727
                     /locus_tag="VQT45_000449"
     CDS             43026..43727
                     /locus_tag="VQT45_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit R"
                     /protein_id="HET2358827.1"
                     /translation="MYSGFTHYKYYRAEIIRKVQEPEFWKEVNLSDLEKIRLAIRDLL
                     QFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHYLKTHLDEESISKL
                     YHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREIIGLDRESANRIFSK
                     FLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQLLFQHQLPVLRNI
                     VQIIELINNRAGEAA"
     gene            complement(44127..45473)
                     /locus_tag="VQT45_000450"
                     /pseudo
     CDS             complement(44127..45473)
                     /locus_tag="VQT45_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
     gene            45535..45729
                     /locus_tag="VQT45_000451"
     CDS             45535..45729
                     /locus_tag="VQT45_000451"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2358828.1"
                     /translation="MSSKKHPLGEKRNHTGSKLRQGFWMVFRLGVNNWGFKEIENKKP
                     SKNSIAGENEIILNENQRAN"
     gene            45707..45907
                     /locus_tag="VQT45_000452"
     CDS             45707..45907
                     /locus_tag="VQT45_000452"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2358829.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDKTDEVSSKHGFEVVDETDEVS
                     NHTYGKATLTRIEEIFEEYKSS"
     gene            complement(45987..46483)
                     /locus_tag="VQT45_000453"
                     /pseudo
     CDS             complement(45987..46483)
                     /locus_tag="VQT45_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT        14097 a         8334 c        10234 g        13818 t
ORIGIN      
        1 acaggcattc aaagagaagc actacgagaa tacgattctc catagtgacc aaggctggca
       61 atatcaacac gattcttatc atcagttcct agagagtaag ggaattcaag catccatgtc
      121 acgtaaggga aacagcccag acaatggtat gatggagtcc ttctttggga ttctgaaatc
      181 ggaaatgttt tacggttatg agaagtcgtt tcagtcgctt aagcaattgg aacaagccat
      241 tatagactat attgattact acaacaataa acgaattaag ataaaactaa aaggacttag
      301 ccctgtgcaa tacagaacta aatccttcgg ataaattaat tgtctaactt ttggggtgca
      361 gttcacagaa ctggcatttt attttttagg atcttgatgg gttaggttca atccccaagg
      421 gaccaaattt tcagttttat ttttgatacg agctatattg tccttatgac gaatgataat
      481 caaactagca agtgctaaga taatagcgat gaagagagag tcatagttac tcaggataaa
      541 accaaaaagt ggaaagagca gaaccccgat aacagccgcg atcgatgctg tgacactaga
      601 cagtgaaatc atactgccaa gatagagagc tccaaagaag ataatcgcaa ggtagagaca
      661 gaagataggc gcaaatccga aaattactcc agcactggtt gcgacagcct taccaccttt
      721 aaatcctgca aagataggga aggtatggcc gataacagcc aaaagtccaa agatgagagg
      781 agaaacgcct tgtagatgaa aaataatcgg aagcagcgtt gctagggttc ctttgaaaaa
      841 gtcaatcaca aaggttgcca taccagcttt cttacctaaa atgcggaagg tattggtcgt
      901 tccagtgtta ccagaaccat gctcgcgtag attgatttga aagaatactt gtccaatcca
      961 gagaccagat ggaatcgaac ccagcagata ggctaggatt aataaaacta ttgtaatcat
     1021 actcctatta tatcatgaat tgggaaagaa aagcagagaa tctctgctaa aattgtcaca
     1081 tcggagaaag aaaaattttg caaaatcctt ggaaaacctg tagaatagta aagatgaacg
     1141 aataggaggt tccttgtgtc aaaaaaggaa atcaatatta acaattataa tgatgatgct
     1201 attcaggtgc tagaagggtt ggatgcggtc cgaaaacgtc cagggatgta tattggatcg
     1261 accgatggcg ctggtcttca tcacctagtt tgggaaatcg ttgataatgc agtcgatgaa
     1321 gccttgtctg ggtttggtga tcgtatcgat gtaaccatca ataaagacgg tagtctaacg
     1381 gttcaagacc atggacgtgg gatgccgaca ggtatgcacg ctatgggaat tccaactgtt
     1441 gaggttatct ttaccattct tcatgccgga gggaaattcg gtcaaggtgg ctataagaca
     1501 tcaggtggac ttcacggagt gggttcttcc gttgttaacg ccctttctag ctggttagaa
     1561 gttgaaatta cccgtgatgg cgcagtttac aagcaacgtt tcgaaaatgg tggaaaacct
     1621 gtcacgactt tgaagaaaat cggtacagca cccaagtcta aaacaggcac caaagttact
     1681 tttatgcctg acgcgactat attttctacg acagatttca agtacaatac catttcagag
     1741 cgccttaatg aatcagcctt tctcttgaaa aatgtgacct tgtctttaac ggacaagcga
     1801 acagatgaag cgattgagtt ccactatgag aatggagtac aagattttgt ttcttatctc
     1861 aacgaagata aggaaatctt gacgccagtt ctttactttg aaggggaaga caatggtttt
     1921 caagtggaag tagccctcca gtacaatgac ggattctcag ataacattct atcctttgtc
     1981 aataacgttc gcaccaagga cggtggaacg cacgagacag gactcaagtc tgccattacc
     2041 aaggtcatga atgactatgc acgtaaaaca ggtcttctca aggaaaaaga taaaaacctt
     2101 gaaggttcag actatcgtga gggactagcg gccgttcttt ctatcttagt tcctgaagaa
     2161 cacttgcagt ttgaaggaca gaccaaggat aaactaggaa gccccctagc tcgcccagtt
     2221 gtggatggaa tagtggctga taagttgacc tttttcctta tggaaaatgg ggaattagct
     2281 tctaacctca tccgcaaggc tatcaaggcc cgtgatgctc gtgaagcagc acgtaaggcg
     2341 cgtgatgaga gccgaaatgg gaagaaaaac aagaaagata agggcttgtt gtctgggaaa
     2401 ttgaccccag cccaatctaa gaatcctgct aagaatgaac tctatctagt tgagggggac
     2461 tctgccggtg gttctgccaa acaaggtcgt gaccgcaagt tccaggctat tctacctctt
     2521 cgtggtaagg ttatcaatac agccaaggcc aagatggcgg atatcctcaa aaatgaagag
     2581 atcaatacca tgatttatac cattggtgcg ggtgttggag cagacttctc tattgaagat
     2641 gccaactatg ataagatcat tatcatgacc gatgcggata ccgacggtgc ccatatccag
     2701 accttgctct tgacattttt ctaccgttac atgcgtccgc tagtcgaggc aggtcatgtc
     2761 tatattgccc tcccacctct ttacaagatg tccaaaggta aaggaaagaa agaagaagtg
     2821 gcctacgctt ggacggacgg agaactagaa gaactccgta aacagttcgg taaaggcgct
     2881 accctccaac gatacaaagg acttggtgag atgaatgcgg accagctctg ggaaacaacc
     2941 atgaacccag aaacacgtac cctcatccgt gtcacaattg aagatttagc gcgcgccgaa
     3001 cgccgcgtca atgttctcat gggagataag gtagaaccac gccgtaaatg gattgaagat
     3061 aatgtcaagt ttacgctaga agaagcgaca gtgttttaat gaaagaaaat aatatgttag
     3121 taaactggaa attagagtcg gatgtgaatg actatgtgaa aaagcagttt gaaaatcttg
     3181 gtttgaaaaa attgcaggat tattaatgaa gaatctgcta tgagtgctta tctcaaagag
     3241 gcgcttaagg gagcggctaa gacacaaact aagactaatt ttggaaaacc agattttcat
     3301 attgaaaaat acaaacagga tagtttggtt acttatcgta actgaacacg ggaggaattc
     3361 ccgtaaaata tcttttactg cataaaaacc tactctacat tctttgaaag gagttgaaca
     3421 cgccctagat actgtgtgaa aaagataaat tctcttgtga gtttgcttac ttcaagaatt
     3481 ttctattttc acttggtatt ttatgggctt tgtatcttat gtctaacatt caaaacatgt
     3541 ccctggagga catcatggga gagcgctttg gtcgctactc caagtacatt attcaagacc
     3601 gggctttgcc agatattcgt gatgggttga agccggttca gcgccgtatt ctttattcta
     3661 tgaataagga tagcaatact tttgacaaga gctaccgtaa gtcggccaag tcagtcggga
     3721 acatcatggg gaatttccac ccacacgggg attcttctat ctatgatgcc atggttcgta
     3781 tgtcacagaa ctggaaaaat cgtgagattc tagttgaaat gcacggtaat aacggttcta
     3841 tggacggaga tcctcctgcg gctatgcgtt atactgaggc acgtttgtct gaaattgcag
     3901 gttaccttct tcaggatatc gagaaaaata cagttccttt tgcatggaac tttgacgata
     3961 cggagaaaga accaacggtc ttgccagcag cctttccaaa cctcttggtc aatggttcga
     4021 ctgggatttc ggctggttat gccacagaca ttcctcccca taatttagct gaggtcatag
     4081 atgctgcagt ttacatgatt gaccacccaa ctgcaaagat tgataaactc atggaattct
     4141 tgcctggacc agacttccct acaggggcta ttattcaggg tcgtgatgaa atcaagaaag
     4201 cttatgagac tgggaaaggg cgcgtggttg ttcgttccaa gactgaaatt gaaaagctaa
     4261 aaggtggtaa ggaacaaatc gttattactg agattcctta tgaaatcaat aaggccaatc
     4321 tagtcaagaa aatcgatgat gttcgtgtta ataacaaggt agctgggatt gctgaggttc
     4381 gtgatgagtc tgaccgtgat ggtcttcgta tcgctatcga acttaagaaa gacgctaata
     4441 ctgagcttgt tctcaactac ttatttaagt acaccgacct acaaatcaac tacaacttta
     4501 atatggtggc gattgacaat ttcacacctc gtcaggttgg gattgttcca atcctgtcta
     4561 gctacatcgc tcaccgtcga gaagtgattt tggcgcgttc acgctttgac aaagaaaagg
     4621 ctgagaaacg tctccatatc gtcgaaggtt tgattcgtgt gatttcgatt ttggatgaag
     4681 tcattgctct tatccgtgct tctgagaata aggcggacgc caaggaaaac ctcaaagtta
     4741 gctatgattt tacggaagaa caggctgagg ctatcgtaac tttgcaactg taccgtttga
     4801 ccaataccga tgtggttgtc ttgcaggaag aagaagcaga gcttcgtgag aagattgcta
     4861 tgctggcggc tattatcggt gatgaaagga ctatgtacaa tctcatgaag aaagaacttc
     4921 gtgaggtcaa gaagaaattt gcaactcctc gtttgagttc tttagaagac actgcgaaag
     4981 caattgagat tgatacagct agtcttatcg ctgaggaaga tacctacgtc agcgtgacca
     5041 aggcaggtta catcaagcgt accagtccac gttcctttgc ggcttccacc ttggaagaaa
     5101 ttggcaagcg tgatgatgac cgtttgattt ttgttcaatc tgccaagaca acccagcacc
     5161 tcttgatgtt cacaagtctt ggaaatgtca tctacagacc aatccatgag ttggcagata
     5221 ttcgttggaa ggacatcgga gagcatctga gccaaaccat cacaaacttt gaaacgaatg
     5281 aagaaatcct ttatgtggaa gtactggatc agtttgacga tgcgacaacc tactttgcag
     5341 tgactcgcct tggtcaaatc aaacgggtag agcgaaaaga attcactcca tggcggacct
     5401 atagatctaa gtctgtcaag tatgctaagc tcaaagacga tacagatcag attgtagcag
     5461 tggctccgat taaactagat gatgttgtct tggttagtca aaatggttat gccctgcgtt
     5521 tcaatatcga agaggttccg gttgtcggtg ctaaggcagc aggtgtcaag gctatgaatt
     5581 tgaaagaaga tgatgtcctc caatctggct ttatctgtaa tacttcgtcc ttctacctct
     5641 tgacccagcg tggaagcttg aaacgtgttt ctattgagga aattctagca accagccgtg
     5701 ccaaacgagg attacaagtc ttgcgtgagt tgaaaaacaa accgcatcgt gtcttcttgg
     5761 caggagcagt tgcagagcaa ggatttgttg gcgatttctt cagtacggaa gtggatgtga
     5821 acgaccaaac tctgcttgtc caatccaata aaggaacaat ctatgaaagc cgattgcaag
     5881 acttgaactt gtcagaacgc actagcaatg gaagcttcat ttctgacacg atttcagatg
     5941 aagaagtttt tgacgcttat cttcaggaag tagttactga agataaataa gtgaaatgaa
     6001 gaatcagttc taagagctgg tttttattgg agaaattttc tgaaaattac aaaatatact
     6061 tgctatttta gaaaaatagt gtagaatata agaaataggt ttttagaata aggagtggaa
     6121 tatgacagta acgattgatt gggaaaacct cggtttttcc tatatgaaat taccttatcg
     6181 ctatcttgct catttcaaaa atggacaatg ggatcaagga gagcttacag aggatgcaac
     6241 tttgcatatt tcagagtctt ctccaagtct tcactatgga caacaagcat ttgaaggttt
     6301 gaaagcttat cgtactaagg atggcagtgt tcaactgttc cgtcctgatg aaaatgctaa
     6361 acgtctgcaa cgtacatgtg accgtctctt gatgccacaa gttccgacag acatgtttgt
     6421 agaagcttgt aaagcagttg tccgtgcgaa tgaagaatac gtaccaccat acggaacagg
     6481 tggaacctta tatcttcgcc ctcttttgat tggtgtcgga gatattatcg gggtaaaacc
     6541 ggcagaagag tacattttca ccatctttgc tatgccagtt ggaaattact ttaaaggtgg
     6601 tttggtccca accaacttct tgattcagga tgagtacgac cgtgcagcac caaatggtac
     6661 aggtgcggct aaggttggtg gaaactatgc tgcaagtctc ttaccaggaa aaatggccaa
     6721 gtcacgtcat ttctcagatg ttatctatct ggacccatca actcatacaa agattgaaga
     6781 agtcggatca gctaacttct ttggaattac agctgataat gaatttgtaa caccattgag
     6841 tccatctatc ttgccatcta ttaccaagta ttccttgctt tatttggcag aacatcgctt
     6901 gggattaact cctattgagg gtgatgttcc aattgataat cttgaccgtt ttgtagaggc
     6961 aggtgcctgt ggtacagcag cggttatttc tccaattgga ggtattcaac atggtgatga
     7021 tttccatgta ttctatagtg aaacagaagt aggtcctgtg acgcgtaaat tatataatga
     7081 attgacgggt attcagtttg gcgatattga agcgccagaa ggttggattg taaaagtaga
     7141 ttaaaataaa ccaaaggaga ttttttatga aatagaaaaa gtggctctta acagcaggag
     7201 tggtcctgag cacgtcagct attttagtgg cttgtggaaa aactgataaa gaagcagatg
     7261 caccgacaac attttcttat gtctatgcag tagatccagc atcattgggc tacagtatag
     7321 cgactcgaac atcgaggaca gacgttattg gaaatgttat tgatggtttg atggaaaatg
     7381 ataaatacgg caatgttgct ccttctcaaa aagactatga tttgaacagt acaggatggg
     7441 ctccaagcta tcaagatcca gcgtcttact tgaatattat ggatccaaaa tctggttctg
     7501 acatgaaaca ccttggcatt acgaaaggaa aagataagga tgttgtagct aaacctggtt
     7561 tggataaata taagaaattg ttagaagatg ctgtttctga gaccactgac ctagagaaga
     7621 gatatgaaaa atatgccaaa gctcaagctt ggtcgacaga tagttcatta ttgatgccaa
     7681 cagcttcatc tggtggtttt ccagttgtaa gtaacgtagt accattctca aaaccatact
     7741 cacaagttgg tattaagggg gaaccatata tctttaaagg aatgaaattg caaaaagata
     7801 ttgttacaac aaaagaatat aacgaggttt ttaaaaaatg gcaaaaagaa aaattggaat
     7861 ccaatagcaa ataccaaaaa gaactagaaa aatacattaa ataaggaatg gtattgatct
     7921 tgataaaatt tttaaaatac tgtcattttg aatataaagg agtttgatat ggagtggatt
     7981 agattaatag gaatagcaat cattgttgtg ggttttattt taaaatttga tacaattgca
     8041 acagtagtct tagctggttt ggttacagct ttagtttcag gtgtttctct cgttgaattt
     8101 ttggagattt tgggaaaaga atttagcaat cagcgagtgc tcacgatttt tatggttacc
     8161 ttgcctcttg tggggctgtc agaaaccttt ggactcaagc aacgatcaat cgatttgatt
     8221 cgaaagatta aaggtctgac agttggaaac ttctatacag tttatttctt tattcgagag
     8281 ttagctggtt tcttttcaat tcgtctagga ggacaccctc agtttgtcag acctttggtt
     8341 caacctatgg gagaagcagc tgcagagtct caattaggta gaaagttaac agaggttgaa
     8401 gatgagacaa taaaagcgcg tgcggctgcg aatgaaaatt ttggaaattt ctttgctcaa
     8461 aatacgtttg taggtgctgg gggagtcctc ttgatagggg gaacattaga tcagttaggc
     8521 tatgaaagca attatgcagg gattgcttct acatctatta ttgttgctgt tataacactt
     8581 attgtagtgg ggatttacaa ttatttattt gataaaaaat tgatatcaaa aaagactagg
     8641 ggaggagaac aaaaatgaca gagttggcaa agcaactatt agagttgacc tatattgtga
     8701 ttggttgtca atttctccat acagcctatt gtagttataa agataaaaca aacccagttc
     8761 gacttgggac atctgcattt tggactctat tgtctattac gtttataggt ggttcctata
     8821 tgccaaatat gagtattggt attattgtaa tcctattatc gctgttaaca ttgtttaagc
     8881 aagtccgtat cggaaccttg ccatccttag atgaaatgaa agccaatatt gaatctaaca
     8941 ggttgaaaaa taaaattttt attccagtta tgctgatggc aatacttgcg ttggtcttag
     9001 cgcaaatgat tccagaattt agcaagattt cgattagcct tgccgccttg tttgctacaa
     9061 tttctgttct tgtgattacc aatagtcacc ctaagagtct gttatcagaa aataatcgaa
     9121 tgactcagca agtttcaaca agtgggattg ttcctcaatt attaggggct ttgggggcta
     9181 tttttactgt agcaggtgtt ggtgatgtta tctctcatct gattagcggt attgttcctt
     9241 cagatagtcg ctttatagga gttttggctt atgttcttgg aatggttcta ttcacaatga
     9301 ttatgggaaa tgcttttgca gcattcaccg ttattacagc aggtgttgga gttccctttg
     9361 tatttgctct gggagctaat ccaattgtgg ctggtgctct tgccatgaca gcaggttatt
     9421 gtgggacctt attgacccca atggctgcta attttaacgc tctaccagca gcattgatgg
     9481 atatgaaaga tcagaatggc gttataaagg ctcaagcagg tgttgctcta gtaatgattg
     9541 ttattcacat attcttaatg tactttctcg cattttagta aaggaaaata aaatgaaaat
     9601 attggttaca ggttttaatc cttttggagg tgaaaagatt aatccagctt tggaggctgt
     9661 aaaattatta ccatctgaga ttaatggggc tgaagttcgc tgggtagaaa ttccaacggt
     9721 tttttataag tcgtcagaag ttttagaggc agaaatatta cgatatcaac cagatgctgt
     9781 actttgtatt ggacaagcag gcggcaggac cggcttaaca cctgaacgag tggctattaa
     9841 tcaagatgat gctcgcatac ctgataacga aggcaatcaa ccaattgata caccgattcg
     9901 tattgatgga gcatcggcct attttagtag tttacctatc aaagcgatgg tacaagctat
     9961 caaaaaacag ggacttccgg cagttgtatc caatagtgca ggaacctttg tttgcaatca
    10021 tttgatgtac caagctcttt atttagtgga taaaaaattc cctaatatga gagcaggttt
    10081 catgcatatt ccatatatga tggaacaagt agtaaataag ccgaatactg caggaatgag
    10141 tctatgtgat attgtaagag gcatagaggt agctattgaa gctattgtag actacaaaga
    10201 taaggatttg cagttagtag gcggtgagac tcactgataa cctaaaaagg atagtcaatt
    10261 atgcttgttt actaactatt aactatgcta aatcaattga ggttgtttac ataaaactct
    10321 atatcagaga agcctgatat agagtttttt cttgctagtt ttaggatttt cttgtaaaat
    10381 agaaaaagtg aagagaggta tgaaatgagc aagaaagata aaaaaatcga aattcaagta
    10441 gcggatgcca aagttaatgt tggtaaagac agttttgaag gttatacatt gactatcggt
    10501 aaaaaagtta tcggagaaat tgccgaatta gacggacaat ttgccattat aaagaatggg
    10561 aatgtcgata gtttttataa aaaattggaa aaagctgtgg aaattttgat tgaaaattat
    10621 aatttagcaa aataagtctt gtttttttga aattttcatg atataatagt ccatgttgat
    10681 tgtaggagag atagcgaaga ggctaaacgc ggcggactgt aaatccgctc cttcgggttc
    10741 gggggttcga atccctctct ctccatttca ttaatggggt atagccaagc ggtaaggcaa
    10801 gggactttga ctccctcatg cgttggttcg aatccagcta ccccagttct taggtaataa
    10861 tcaagataaa aagcaaaata tcttagggta ttttattttt ataattgaaa gacgtgaatg
    10921 atatgaacat gtccttgcgg gtgcttagga aaaaaattat aagtatgtca agtttaagaa
    10981 aaacttgatt gttggaggat tttttagatg aacgaatttg aagatttgct aaatagcgtt
    11041 agtcaagttg agactggtga tgttgttagt gctgaagtat tgacagttga tgcgactcaa
    11101 gctaacgttg caatctctgg aactggtgtt gaaggtgtct tgactcttcg cgaattgaca
    11161 aacgatcgtg atgcagatat caatgacttt gttaaagtag gagaagtatt ggatgttctt
    11221 gtacttcgtc aagtagttgg taaagatact gatacagtta cataccttgt atctaaaaaa
    11281 cgccttgaag ctcgcaaagc atgggacaaa cttgttggtc gcgaagaaga agttgttact
    11341 gttaaaggaa cgcgtgccgt taaaggtgga ctttcagtag aatttgaagg tgttcgtgga
    11401 tttatcccag cttcaatgtt ggatactcgt ttcgtacgta acgctgagcg ttttgtaggt
    11461 caagaatttg atactaaaat caaagaagtt aacgctaaag aaaaccgctt catcctttca
    11521 cgtcgtgaag ttgttgaagc agctactgca gcagctcgcg ctgaagtatt cggtaaattg
    11581 gctgttggtg atgttgtaac tggtaaagtt gctcgtatca caagcttcgg cgctttcatc
    11641 gaccttggtg gtgttgacgg attggttcac ttgactgaat tgtcacatga acgtaacgta
    11701 tcaccaaaat cagttgtaac tgttggtgaa gaaattgaag tgaaaatcct tgatcttaac
    11761 gaagaagaag gacgtgtatc actttcactt aaagcaacag taccaggacc atgggatggc
    11821 gttgagcaaa aattggctaa aggtgatgta gtagaaggaa cagttaaacg tttgactgac
    11881 ttcggtgcat ttgttgaagt attgccaggt atcgatggac ttgttcacgt atcacaaatt
    11941 tcacacaaac ggattgaaaa tccaaaagaa gctcttaaag ttggtcaaga agttcaagtt
    12001 aaagttcttg aagttaacgc agatgcagaa cgcgtgtcac tttctattaa agctcttgaa
    12061 gaacgtccag cccaagaaga aggacaaaaa gaagaaaaac gtgctgctcg tccacgtcgt
    12121 ccaagacgtc aagaaaagcg tgatttcgaa cttccagaaa cacaaacagg attttcaatg
    12181 gctgatttgt ttggtgatat cgaactttaa tcaaattgaa aattcacaaa atcctttgtt
    12241 tactaaacaa gggatttttc ttttgtctct gctccttttt tgatataata gttctatgtt
    12301 aaaatcagaa aaacaatcac gttatcaaat gttaaatgaa gaattgtcct tcctattgga
    12361 aggcgaaacc aatgttttgg ctaatctttc caacgccagt gctcttataa aatcacgttt
    12421 tcctaatacc gtatttgcag gcttttattt gttcgatgga aaggaattgg ttttaggtcc
    12481 cttccaagga ggtgtttcct gcatccgtat tgcactaggc aagggtgttt gtggtgaggc
    12541 agctcacttt caggaaactg ttattgttgg agatgtgacg acctatctca actatatttc
    12601 ttgtgatagt ctagctaaaa gtgaaattgt ggtgccgatg atgaagaatg gtcagttact
    12661 tggagttctg gatctggatt cttcagagat tgaggattac gatgctatgg atcgagatta
    12721 tttggaacaa tttgtcgcta ttttgcttga aaagacaaca tgggacttta cgatgtttga
    12781 ggaaaaatct taatgtatca agcactttat cgaaaatata gaagtcaaaa cttctcccag
    12841 ttagttggtc aagaagttgt ggctaagact cttaaacaag cggtggagca agagaaaata
    12901 agtcacgctt atcttttttc tggtcctcgt ggaacgggaa aaaccagtgt tgctaaaatc
    12961 tttgccaagg ctatgaactg tcccaatcaa gtgggtggcg aaccttgcaa taactgctat
    13021 atttgtcaag cagtgacgga cggtagttta gaagatgtca ttgaaatgga tgcagcttct
    13081 aataatgggg tagatgaaat tcgcgaaatt cgtgataaat ctacctatgc gcctagcctt
    13141 gctcgttata aggtttatat catagatgag gttcacatgc tgtctacagg ggcttttaat
    13201 gccctcctaa agacgctgga agaaccaaca cagaatgtag tctttatttt ggccactact
    13261 gaattacaca agattcctgc tactattcta tcccgtgtgc aacgttttga gtttaaatca
    13321 attaagacac aggatattaa ggaacatatt cactatatct tagaaaaaga aaatatcagt
    13381 tctgaaccag aggctgtgga aatcattgcc agacgggcgg aaggtggaat gcgggacgcc
    13441 ttgtctattt tggatcaagc cctgagtttg acacagggaa atgagctgac gactgctatc
    13501 tctgaagaaa ttactggcac tattagccta tcagccttgg atgattatgt ggcggccttg
    13561 tctcaacagg atgttcccaa agctttgtct tgcttgaatc ttctttttga caatggtaag
    13621 agcatgactc gttttgtgac cgatcttttg cactatttaa gagacttgtt aattgttcaa
    13681 acagggggag aaaatactca tcatagttca gtctttgtag aaaatttggc acttcctcaa
    13741 aaaaatctgt ttgaaatgat tcgcttagca acagtgagtt tagcagatat taagtctagt
    13801 ttgcagccca agatttatgc tgaaatgatg accgtccgtt tggcggaaat caagcccgaa
    13861 ccagctctat caggagcggt tgaaaatgaa attgctacgc tgagacagga agttgcccgt
    13921 ctcaaacaag agctttctaa tgtaggtgcg gttcctaaac aagttgcacc agctcctagt
    13981 cgaccagcta cgggcaaaac agtctatcgt gtcgatcgca ataaagtgca atctatctta
    14041 caagaggccg tcgaaaatcc tgatttagca cgtcaaaatc taattcgttt gcagaatgcc
    14101 tggggagagg taattgaaag tctaggtggg ccggacaagg ctctgctagt tggttctcaa
    14161 ccggttgctg ccaatgaaca ccatgctatt cttgcttttg agtctaactt caatgctggt
    14221 caaactatga aacgagacaa tctcaatacc atgtttggca atatcctcag tcaggcggca
    14281 ggtttttcac ctgagatttt agctatttcc atggaggaat ggaaagaagt tcgcgcagcc
    14341 ttttcagcca aagccaaatc ttctcaaact gaaaaagaag tagaagaaag cctgattcca
    14401 gaaggatttg aatttttggc tgataaagtg aaggtagagg aagactaaag aaagatttcg
    14461 tgatacaata agtttatgaa taaacaacaa tttattatta tggcgctgtt tacagctgct
    14521 gagacctatt ttttcaatga agcctggatg actggccgct atattatggc agccttttgg
    14581 gcaattttac tctttagaaa tttccgagtc agttatgtga tgggcaaaat cgttgatgtc
    14641 atcgatcagc attttaatag gaaagactag ccctcagctt ccagacaaaa tcaaagcctt
    14701 ttaggctttt ttttgttata ctagaaaagt atatttatag aatttttgct ctatttctgg
    14761 ggaaatcaga cgtttttcta gtaagtactg taaaagtttt gaaaaagaaa ggaactatca
    14821 tgtcagtatt agagatcaaa gatcttcacg ttgagattga aggaaaagaa attttaaaag
    14881 gggttaacct gaccctgaaa acaggagaaa ttgccgctat catgggacca aatggtacag
    14941 gtaaatcgac tctttctgcc gctatcatgg gaaatccaaa ctatgaagta actaaaggtg
    15001 aagttttgtt tgatggcgta aacatccttg agttggaagt ggatgagcgt gcgcgtatgg
    15061 gacttttcct tgctatgcaa tacccatcag aaatccctgg aattaccaat gctgagtttc
    15121 ttcgtgccgc tatgaatgcg ggtaaagaag atgatgagaa gatttcagtt cgtgagttta
    15181 ttactaggct agatgaaaaa atggaattgc tcaacatgaa agaagaaatg gcagagcgtt
    15241 acctcaacga aggcttctct ggtggtgaga aaaaacgcaa tgaaattctt caacttttga
    15301 tgttggagcc aacatttgct cttttggacg agattgactc aggtcttgat attgacgctc
    15361 ttaaagttgt gtctaaaggt gtcaatgcca tgcgtggtga aggttttggt gctatgatca
    15421 tcactcacta ccaacgtctt ttgaactata tcacacctga tgtggtacac gtgatgatgg
    15481 aaggtcgtgt tgtcctttct ggtggtccag aattggctgc gcgtttggaa cgtgaaggat
    15541 acgcaaaatt agctgaagaa cttggctacg actacaagga agaattgtaa tttcctcgta
    15601 tcttttagga gaagtaaatg actagagaaa atattaaact tttttcagaa atgcacgctg
    15661 aaccaagctg gttggctgat ctccgtcaaa aagcttttga caagattgag actttggaat
    15721 taccagttat tgagcgtgtc aaattccacc gttggaatct gggtgatgga acgattacag
    15781 aaaatgagcc atcagcaaat gttccagatt tcacagcttt agatcatcac ttgaagttgg
    15841 tgcaagtagg aactcaaact gttttcgaac aaactccagt tgagttagct gaacagggtg
    15901 ttgtcttcac agactttcac tcagctttag aagaaattcc agagctgatc gaagaattct
    15961 tcatgtcatc tgttaagtat gatgatgaca agttggcggc ttaccacaca gcttacttta
    16021 acagtggtgc tgtactctat attccagata acgtagaaat cacagagcca attgaaggaa
    16081 ttttctacca agatagcgat agcaatgtgc cgtttaacaa gcatattatg attatcgctg
    16141 gtaaaaattc taagattaat tatctggagc gtttagagtc acgcggtgaa ggaagtgcca
    16201 aagcaactgc taatatcaca gtagaagtga ttgcacgttc aggtgcgcaa gtcaagtttg
    16261 ctgctatcga ccgtctaggt gaaaacgtca ctgcctacat tagccgtcgt ggtaaattag
    16321 gcaacgatgc aagtattgac tgggctatcg gtgtcatgaa cgaaggaaat gtcgttgctg
    16381 attttgatag tgacttgatt ggtaatggta gctatgctga cctcaaggtt gtagctcttt
    16441 caagtggtcg tcaggtacaa gggattgata ctcgtgtaac taactatggc tgcaactcta
    16501 tcggaaatat cctacaacat ggggttatcc ttgaaaaagc aactttgact ttcaatggta
    16561 tcggccacat catcaagggt gctaagggag cagatgccca acaagagagc cgtgttctca
    16621 tgctttcaga ccaagcgcgt tcagatgcta acccaattct tttgattgat gaaaatgatg
    16681 tcactgcagg acacgcagcg tctatcggac aagttgatcc agaagacatg tattacctca
    16741 tgagtcgtgg attggataag gcaactgcag agcgtttggt tgttcgtggt ttccttggat
    16801 ctgttatcgt ggagattcca gtcaaggaag ttcgtgatga aatgattgca actatcgaag
    16861 agaaattgtc aaaacgctaa ggggaagcct atgttagatg tagaagcgat tcgcaaggat
    16921 tttccaattt tagatcagat tgtcaatgat gaacctctgg tctatctgga caatgctgcg
    16981 acgacacaaa aaccactagt agttctgaaa gctattaaca gttactatga gcaggacaat
    17041 gccaatgttc accgtggtgt ccatacctta gcggaacgag cgacagcttc ttatgaagct
    17101 gctcgtgaaa ccattcgtaa gtttattaat gcaggctcta caaaggaagt tctctttacc
    17161 agaggaacga caaccagcct taactgggtg gcacgctttg ctgaggaaat tctcactgag
    17221 ggagaccagg tcttgatttc agtaatggaa caccattcta atatcattcc atggcaggaa
    17281 gcttgtcgaa agactggagc agagcttgtc tatgtctatc ttaaagacgg tgccttggat
    17341 atggaggatt tgcgagctaa attgactgat aaggttaaat ttgtttccct agctcatgcc
    17401 tccaatgttc ttggtgtggt caatccgatc aaggaaatca ctcaattagc ccaccaagtt
    17461 ggggcaatca tggtagtgga tggtgctcaa tctacacctc atatgaagat tgatgtccag
    17521 gacttggatc tggacttttt cgccttttcg ggtcacaaga tggctggtcc gactggtatc
    17581 ggtgtccttt acggcaaaga aaagtatctt gagcaaatgt ctccagtaga atttggcggc
    17641 gagatgattg attttgtcta cgagcaatcc gctagttgga aggaattgcc ttggaaattt
    17701 gaggctggaa cgccaaatat ggcaggagct attggacttg cgactgcagt tgattatctg
    17761 gaaaagattg gtatggatgc cgttgaagct catgaacagg aattgattgc gtacgtctat
    17821 ccaaaactgc aggcaattga gggattgacc atttacggtt ctcaggattt ggctcaacgt
    17881 tcgggtgtta ttgcctttaa cctaggtgat ctccatcctc acgatcttgc gacggctctg
    17941 gattatgaag gagtggctgt tcgtgctggt caccattgtg cgcaaccctt gcttcagtat
    18001 ttggaagtcc cagcatcagc tcgtgcaagt ttttatatct ataataccaa ggcagattgc
    18061 gacaaactag tcgatgccct acaaaagaca aaggagtttt tcaatggcac tttctaaact
    18121 agatagcctt tatatggcag tggtagcaga ccattcgaaa aatccacatc accaagggaa
    18181 gttagaagac gctgagcaaa tcagtctcaa caatccgact tgtggggatg tcatcaacct
    18241 ctctgtcaag tttgatgcag aggaccgttt ggaagatatt gcttttctaa attcaggatg
    18301 cacgatttca actgcttctg ctagtatgat gacagatgcc gttttaggaa aaaccaaaca
    18361 agaaatttta gaactggcga ctattttttc tgaaatggtt caagggcaaa aagatgagcg
    18421 tcaagaccaa cttggagacg cggcattctt gtcaggtgtt gccaaattcc ctcaaagaat
    18481 caagtgtgca accctagctt ggaatgccct taagaaaaca attgaaaatc aagaaaaaca
    18541 gtaagacaag tttcttttgt cttatgaatt attagaaatg aagaaaggat attatggctg
    18601 aagaaagagt agaaccaaaa ccaattgacc ttggtgaata taaatttggt ttccatgacg
    18661 atgtagagcc tgtcttatcg acaggaaaag gactcaacga aggtgttatt cgtgaattat
    18721 ctgctgctaa gggtgagcct gagtggatgt tggagttccg tttgaagtct tatgaaacct
    18781 tcaaaaaaat gcccatgcaa acttggggag cagacttgtc agagattgac tttgatgact
    18841 taatctacta ccaaaaacca tctgacaaac cagcccgttc ttgggatgat gtacctgaaa
    18901 agattaaaga aacctttgaa cgtatcggga ttccagaagc tgaacgtgct tatttagcag
    18961 gggcttctgc ccagtacgag tcagaagtgg tttaccacaa catgaaggaa gagttccaaa
    19021 aattaggtat tatctttaca gatacagatt ccgcactcaa ggaataccca gacttattta
    19081 aacaatactt tgcgaagttg gtaccgccga cagataacaa gttggcagcc ctcaactcag
    19141 cagtatggtc gggtggaact tttatctacg tgccaaaagg tgtcaaggta gatattccac
    19201 ttcaaactta tttccgtatc aataacgaaa atataggtca gttcgaacgt accttgatta
    19261 tcgttgatga gggagcaagc gtccactacg tagaaggatg tacagcacca acatattcaa
    19321 gcaatagctt gcacgctgcc attgtagaaa tttttgcttt ggacggagct tatatgcgtt
    19381 atacaactat ccaaaactgg tctgataacg tctataactt ggtaacaaag cgtgctaagg
    19441 ctcaaaagga tgccactgtt gagtggattg atggaaactt gggtgccaaa acgactatga
    19501 aatatccatc tgtttatctt gatggagaag gagcgcgtgg taccatgctc tctatcgcct
    19561 ttgctaatgc agggcaacac caagacacgg gtgctaagat gattcacaat gctccacata
    19621 ccagctcgtc tattgtgtct aaatccatcg ctaaaggtgg aggaaaggtt gactaccgtg
    19681 gacaagtcac ctttaacaag aactctaaga aatctgtttc ccacattgaa tgtgatacca
    19741 ttatcatgga tgacttgtca gcatcagata ctattccatt taatgaaatt cacaactcgc
    19801 aagtggcttt ggaacacgaa gccaaagtat ctaagatttc agaagagcaa ttgtattatc
    19861 tcatgagccg tggattgtca gaatctgagg caactgaaat gattgtcatg ggatttgtag
    19921 aaccctttac aaaagaactt ccaatggaat acgcagttga gctgaaccgc ttgattagct
    19981 atgaaatgga gggatcagtt ggataaaatt tgattttata ctcttcgaaa atctcttcaa
    20041 accacgtcag catcgcctta ccgtatgtat ggttactgac ttcgtcagtt tcatctacaa
    20101 cctcaaaaca gtgttttgag caacctgcgg ctagcttcct agtttattct ttgattttga
    20161 gtattagatt tactcaaaat caaggatttt gaagatgaac ttgtatcaaa aaatcgcggt
    20221 ttaaaatcgc gattttttat aatttctcgt taacaaagcg gacaaactga ttccaccaaa
    20281 cttttaagaa gaaggctttt tcaattttct tgtctgctac catttcgaaa ctagggcgct
    20341 ctgtggtgat gtaaccttga ccaatcaagt ccttgtcttc ataagtcaaa tggccaacca
    20401 ctgttccagc ttcaagtggt gctgggattg ctttggaatc aggtgtgaat tgaacagatt
    20461 gggaagattg attcccaaca cgttcgatta gatagatatc ctctggagcc actgcagtta
    20521 ctgtatcttc ttttccatct tgtacagggg ctttgctatc ttgataggca tcgccttgtt
    20581 gaacgatttt gcgaagtgta aatgtagaag aaatataatc cattagggaa gatgtagctg
    20641 taaatcgagc gtaaggatta ttgtcttgat gatctgcatt taaaacaact gtgatgactc
    20701 tcatgccttt ttcgacagta gtaccaacaa aagactctcc agccttatct gttgttcctg
    20761 tttttagccc atcaaaacca ccacggtaag caggcatacc ttctaacatg tagttggttg
    20821 aagtgattgt catcccagca aaagtagaag aaggtttttt ggtgatttct aagacttgtg
    20881 ggtatttttt gatgaggttg cgagcaacga tagcgacatc ataagcacta agcttatttt
    20941 cctcatcttt tttagaacct gggtaaatgt tatcccctag agtttcattg ttaagacctg
    21001 tcgtattgac aacagtggca tcctgaattc cccattccaa gagttttgcc cgcatcatat
    21061 cgatgaaatc tttttctgag ccagcaattt tctcagctag ggcaatagcg gcgctgttgg
    21121 cactagatac cagagttgct tcaagcaact cttcgacagt ataattacgg gcctccatag
    21181 gaatattact ggcttcagaa tttgtcgtca attgataagg ataatcagaa atatctacag
    21241 gagtggagag ggtaatactt ccgttttcca aagcttcata gaccagataa gcagtaatca
    21301 attttgttat ggaagcaatt tcgacaggtt gcgttgcatc cttctcatag agaattttac
    21361 cagtatttgc ctcaacagca atcgcatgtt tagcggcaat ggtaaaatct tgagcaacag
    21421 cagtagaagc accccctaaa agagagacag ttaacaaagt taaaaatatt tttttcatag
    21481 tagtcttatt ctatcataaa gaaaaaaaat attcttgctt taataattca tctgttaagc
    21541 tttttgaaaa tatggtaaaa taaagtgagg gaggtaactc atgtttcgta gaaataaatt
    21601 atttttttgg accacagaaa ttttactctt aaccatcatc ttttacctat ggagacagat
    21661 ggggtctttg attaaccctt ttgttagcgt gcttaataca attatgattc catttttatt
    21721 agggggcttt ctttattatt tgacaaaccc tattgttact ttcttaaata aagtctgtaa
    21781 actcaatcgt ttgcttggta ttttaattac cttgtgtact ttggtctggg gaatggtcat
    21841 aggtgttgtc tatctcttac ctattttgat taatcagtta tctagtttga ttatatctag
    21901 tcaaactatt tatagtcgag tacaagactt aatcatagac ttatctaatt atcctgcgct
    21961 ccagaatttg gatgtagaag ctacaattca gcagttaaac ttatcctatg ttgatattct
    22021 tcaaaatatc ctaaatagcg tatcaaatag tgtggggagc gtcttgtcag ctcttatcag
    22081 tactgttttg attttgatta tgactccagt ttttttggtt tatttcttat tagatggaca
    22141 taaattcttg cccatgcttg aaagaacgat tctaaagagg gatcgcttgc atattgcagg
    22201 cttattaaag aatttaaatg cgacgattgc tcgctatatt agtggagttt cgattgacgc
    22261 aatcattata ggttgtttgg cttatattgg ctatagtatt attggtttaa aatatgcttt
    22321 agtttttgcc attttttctg gtgtagccaa tttaattcct tatgtggggc caagtattgg
    22381 tttgattcct atgatcatcg caaatatatt cactgatccc catagactgc tgattgcagt
    22441 gatttatatg cttgttgttc agcaggtaga tggcaatatc ttatatcctc gaatcgtagg
    22501 aagtgttatg aaggttcatc caatcacgat tttagtttta cttttgttgt caagcaatat
    22561 ctatggtgta gttggaatga ttgtcgcagt gccaacctat tctatcttga aagaaatttc
    22621 taagttctta tcccgtttgt atgaaaatca taaaataatg aaagaacgag aaagagaatt
    22681 agctaagtaa aagtcaggag aaccctgatt tttctttact ggaagtggcc tttagattag
    22741 aagactgaaa ataagttaaa gtcttaaact aattttcaca gctaagaata gtagaagtta
    22801 atctgataaa aatcgaaaaa accagtggaa ttctgtgtca gggtaagttc cactggtttt
    22861 catagtctat taaagttcga atgaaaccta tttatagtag attgaaacta gaatagtaca
    22921 cctctaattc taaaacattg ttagaaatcg atttgactgt cctgatctat tcgttctatt
    22981 cttatttcat tttactatat tttggtgcaa taagtgaaaa gtagtccgaa taatataagg
    23041 attgatttta tagtttttaa actcaaatga attgaaataa agagagtacg aaaattctca
    23101 tctgaaagta ttttagaata attctcttcg tgaatttctt caaaacagat agcttcatct
    23161 taggtatgtg atttcttttt gcatttttga gttagataag gtataatggt tttattgtct
    23221 tttggggtcg ttacggattc gacaggcatt atgaggcata ttttgcgact cgtgtggcga
    23281 cgtaaacgct cagttaaata taactgcaaa aaataacact tcttacgctc tagctgccta
    23341 aaaaccagca ggcgtgaccc gatttggatt gctcgtgttc aatgacaggt cttattatta
    23401 gcgagatacg attaagcctt gtctagcggt ttgataagag attgatagac tcgcagtttc
    23461 tagacttgag ttatgtgtcg aggggctgtt aaaataatac ataacctatg gttgtagaca
    23521 aatatgttgg caggtgtttg gacgtgggtt cgactcccac cggctccatt attcctttgc
    23581 attcttttgc attccttggt aaaacgttgt taaatcaacg ttttttattt ttatctttgg
    23641 tattcctttg cattcttttg ctaaaaaggg agtcacaaac agaccctatt ttaaaaaaag
    23701 gatagaaaaa aggatacaac atttgtcgca tcctaaaaat aatctttttt ccacggaaga
    23761 catgggattc gaacccacgc acgctattac acgcctaccg cgtttccaac acggcctctt
    23821 aagcctcttg agtaatcttc caatacttac tcaaatagtc taccataaag gctcttatct
    23881 tgcaataaaa attctagaaa taagaaaaat gatagatttt gaaagaaaat gataaaaaat
    23941 gcttgacttc aaaagaaagt atgatagaat gaatagtgta aacgataaca ggaggtgatt
    24001 cggtgttaaa aacagagcgg aagcaactga ttttagagga gttaaatcaa catcatgtag
    24061 tttctctaga aaaattagtt agtttgctag aaacgtcaga atcaacggtt cgaagagact
    24121 tggatgagtt ggaagcggaa aacaagcttc gtcgtgtgca tggtggagca gaactccccc
    24181 actccttaca ggaagaagaa accattcaag aaaaatctgt caaaaacctt caagaaaaga
    24241 agttgctggc tcagaaagca gcctctctca ttaaagaaaa agatgtcatc tttatcgatg
    24301 ctggaacaac aactgctttt ttgattcatg aattggtcaa taagaatatt acagttgtga
    24361 ccaactccat tcaccatgcc gctcagttgg ttgaaaagca gattccaact gtcatggttg
    24421 gaggaaacgt caagacggcg acagatgcta gtatcggtgg cgttgctctt aaccagatta
    24481 accaattgca ctttgaccgt gcctttatcg gaatgaatgg tgttgacgat ggctattata
    24541 cgactcctga tatggaggag ggagctgtga aaagagctat tttggagaat gccaagcaga
    24601 cctacgtctt ggtggattcg tcaaaaattg gacaaacttg ctttgccaag gtagcaccac
    24661 tcaaacgcgc tatcgttatc actagtcaag ggcatgagct cttgcaggtt attaaggaga
    24721 aaacggaggt aatagaagta tgatttatac agtcacactc aatccatcca ttgactatat
    24781 cgttcgtttg gaccaagtca aagttggtag tgtaaatcgt atggacagtg atgataagtt
    24841 tgctggtggg aaaggaatca atgtcagccg tgtcttgaaa cgtttgaata taccaaatac
    24901 agcgacggga tttatcggtg gctttactgg taaatttatc acagatactt tagcagagga
    24961 agaaatcgag acacgttttg tccaggtggc agaagatact cgtatcaatg ttaaaatcaa
    25021 agcagaccaa gaaacagaaa tcaacggaac gggtccaact gttgaatcgg ttcagctaga
    25081 agaattgaaa gctattttat ctagtctgac agcagaagat acagttgtct ttgcaggttc
    25141 aagtgctaaa aatctaggca atgttatcta taaggatttg atttccttga cgcgccagac
    25201 tggtgcgcaa gtggtctgtg actttgaagg acagacctta attgatagtt tggactacca
    25261 gcctcttctt gtaaaaccaa acaatcatga acttggagcg atttttgggg ttaaactcga
    25321 aagtttagat gaaattgaga aatacgctcg tgagttactg gctaagggtg ctcaaaatgt
    25381 tattatctct atggctggtg atggtgccct tcttgtcaca tctgagggag cttacttcgc
    25441 taaaccaatc aaaggaacag tcaaaaattc agttggagct ggtgattcta tggttgctgg
    25501 attcacaggt gaatttgtca aatcaaaaga cgtagtagaa gccttcaaat ggggagtggc
    25561 ttgcggaacg gcaactacct tctcagatga cttggcaacg gcggaattta ttaaagaaac
    25621 atatggaaaa gttgaggtag aaaaacgatg aaaattcaag acctattgag aaaagatgtc
    25681 atgttgctag atttgcaggc aactgaaaaa acagctgtca tcgacgagat gattaaaaat
    25741 ttgacagacc acggttatgt aacagatttt gaaacattta aagaaggaat tttggcgcgt
    25801 gaagctttga cttctactgg tttgggtgat ggaatcgcaa tgcctcacag caaaaacgct
    25861 gctgtcaaag aagcgacagt tctatttgct aagtcaaata agggtgttga ctacgagagc
    25921 ttggatggac aagcaactga cctcttcttc atgattgcag ctccagaagg tgccaatgat
    25981 actcacttgg cagccttggc agaattgtct caatacttga tgaaagacgg ttttgcagac
    26041 aaacttcgtc aagcaacatc tgcagaccaa gttatcgaac tttttgacca agcttcagaa
    26101 aaaactgagg aacttgttca agcacctgct aatgactctg gtgactttat cgtagctgtt
    26161 acagcttgta caacaggtat tgcccacact tacatggccc aagaagccct tcaaaaagta
    26221 gctgctgaaa tgggggttgg tatcaaggtc gaaaccaacg gtgctagcgg tgttggaaat
    26281 caactaactg cagaagatat ccgtaaggct aaagctatta tcattgcagc agacaaggcc
    26341 gttgaaatgg atcgatttga tggaaaacca ttgatcaatc gtccagttgc tgacggtatc
    26401 cgtaagacag aagagctaat taacttggct ctttcaggag atactgaagt ctaccgtgcc
    26461 gctaatggtg ccaaagctgc aacagcctct aacgaaaaac aaagccttgg tggtgccttg
    26521 tacaaacact tgatgagtgg tgtatctcaa atgttaccat tcgttatcgg tggtggtatc
    26581 atgattgccc ttgccttctt gattgacggt gctttgggtg ttccaaatga aaaccttggc
    26641 aatcttggtt cttaccatga gttagcttct atgttcatga aaattggtgg agctgccttt
    26701 ggtttgatgc ttccagtctt tgcgggttat gttgcctact ctattgctga aaaaccgggt
    26761 ttggtagcag gtttcgtggc tggtgctatt gccaaagaag gttttgcctt tggtaaaatt
    26821 ccttatgccg caggtggtga agcaacttca actcttgcag gtgtctcatc tggtttccta
    26881 ggtgcccttg ttggtggatt tatcgcaggt gccttggttc ttgccatcaa gaaatacgtt
    26941 aaagttcctc gttcactcga aggtgctaaa tcaatccttc tattgccact tcttggaaca
    27001 atcttgacag gatttgttat gctagctgtg aatatcccaa tggctgcaat caacactgct
    27061 atgaatgact tcctaggcgg tcttggagga ggttcagctg tccttcttgg tatcgtcctt
    27121 ggtggaatga tggctgttga catgggtgga ccagttaata aagcagctta tgtctttggt
    27181 acaggtacgc ttgcagcaac tgtttcttca ggtggttctg tagccatggc agcagttatg
    27241 gctggaggaa tggtgccacc acttgcaatc tttgtcgcaa ctcttctttt caaagataaa
    27301 tttactaagg aagaacgtaa ctctggtttg acaaacatca tcatgggctt gtcatttatc
    27361 actgagggag cgattccatt tggtgccgct gacccagctc gtgcgattcc aagcttcatc
    27421 cttggttcag cagtagcagg tggactcgtt ggtcttactg gtatcaaact catggcgcca
    27481 cacggaggaa tcttcgttat cgcccttact tcaaatgctc tcctttacct cgtttctgtc
    27541 ttggtaggag caatcgtaag tggtgtggtt tatggttacc tacgcaaacc acaagcataa
    27601 aaaatagaaa aatgaaaaga ttggaccgtt tggtgcagtc tttttctctt cccgaaatgc
    27661 ctgtgaaata tggtataata gaagaatggc aaacaagaat acaagtacaa caagacggag
    27721 accgtctaaa gcagaactgg aaagaaaaga agcgattcaa cgaatgttga tttcgttagg
    27781 aattgcgatt ttattgattt tcgcagcctt caaattaggg gctgcaggta taacccttta
    27841 taatttaatt cgcttgctag tgggtagcct agcttatctg gcgatattcg gcctattaat
    27901 ctatctcttc tttttcaagt ggatacgaaa acaggaagga ctcttatctg gctttttcac
    27961 catatttgct ggcttactct tgatttttga ggcctacttg gtttggaaat atggtttgga
    28021 caagtccgtt ctaaaaggga ccatggctca ggttgtgaca gatctgactg gttttcgaac
    28081 gactagcttt gctggagggg gcttgatcgg ggtcgctctt tatattccaa cagcctttct
    28141 cttttcaaat atcggaactt actttattgg ttctatcttg attttagtgg gttctctcct
    28201 agtcagccct tggtctgttt acgatattgc tgaatttttc agtagaggct ttgccaaatg
    28261 gtgggaaggg cacgagcgtc gaaaagagga acgctttgtc aaacaagaag aaaaagctcg
    28321 ccaaaaggct gagaaagagg ctagattaga acaagaagag actgaaaaag ccttactcga
    28381 tttgcctcct gttgatatgg aaacgggtga aattctgaca gaggaagctg ttcaaaatct
    28441 tccacctatt ccagaagaaa agtgggtgga accagaaatc atcctgcctc aagctgaact
    28501 taaattccct gaacaggaag atgactcaga tgacgaagat gttcaggtcg atttttcagc
    28561 caaagaagcc cttgaataca aacttccaag cttacaactc tttgcaccag ataaaccaaa
    28621 agatcagtct aaagagaaga aaattgtcag agaaaatatc aaaatcttag aagcaacctt
    28681 tgctagcttt ggtattaagg taacagttga acgggccgaa attgggccat cagtgaccaa
    28741 gtatgaagtc aagccggctg ttggtgtaag ggtcaaccgc atttccaatc tatcagatga
    28801 cctcgctcta gccttggctg ccaaagatgt ccggattgaa gcaccaatcc ctgggaaatc
    28861 cctaatcgga attgaagtgc ccaactccga tattgccact gtatctttcc gagaactatg
    28921 ggaacaatcg caaacgaaag cagaaaattt cttggaaatt cctttaggga aggctgttaa
    28981 tggaaccgca agagcttttg acctttctaa aatgccccac ttgctagttg caggttcaac
    29041 gggttcaggg aagtcagtag cagttaacgg cattattgct agcattctca tgaaggcgag
    29101 accagatcaa gttaaattta tgatggtcga tcccaagatg gttgagttat ctgtttacaa
    29161 tgatattccc cacctcttga ttccagtcgt gaccaatcca cgcaaagcca gcaaggctct
    29221 gcaaaaggtt gtggatgaaa tggaaaaccg ttatgaactc tttgccaagg tgggagttcg
    29281 gaatattgca ggttttaatg ccaaggtaga agagttcaat tcccagtctg agtacaagca
    29341 aattccgcta ccattcattg tcgtgattgt ggatgagttg gctgacctca tgatggtggc
    29401 cagcaaggaa gtggaagatg ctatcatccg tcttgggcag aaggcgcgtg ctgcaggtat
    29461 ccacatgatt cttgcaactc agcgtccatc tgttgatgtc atctctggtt tgattaaggc
    29521 caatgttcca tctcgtgtag catttgcggt ttcatcagga acagactccc gtacgatttt
    29581 ggatgaaaat ggagcagaaa aacttcttgg tcgaggagac atgctcttta aaccgattga
    29641 tgaaaatcat ccagttcgtc tccaaggctc ctttatctcg gatgacgatg ttgagcgcat
    29701 tgtgaacttc atcaagactc aggcagatgc agactacgat gagagttttg atccaggtga
    29761 ggtttctgaa aatgaaggag aattttcgga tggagatgct ggtggtgatc cgctttttga
    29821 agaagctaag tctttggtta tcgaaacaca gaaagccagt gcgtctatga ttcagcgtcg
    29881 tttatcagtt ggatttaacc gtgcgacccg tctcatggaa gaactggaga tagcaggtgt
    29941 catcggtcca gctgaaggta ccaaacctcg aaaagtgtta caacaataaa aaaatagctt
    30001 ctttccaagt ttggagggaa gctattttag tggctattga ttgcttttat tttctgaagt
    30061 tggcgcattg gactgttttt cgttttcagt agcaggttta cttgaagcag gagtagaaga
    30121 gtcctgagtt gctgttttct gatcttcttt tttctcttcc ttgacgctag attttggtgt
    30181 ttcctcttgc tgtgtttttt cttgactagt gttagtctct ttagttggac tggtgttttc
    30241 cttaggggat tccttttgga tttctttgac aatggttgtc gtctggcttg tcgtaggttc
    30301 ttttttaata tttttgttat tatccaaggc gttcataatc gtgatacttg cggtaatcaa
    30361 gccaaggata ctagcgattg tagcaacggt tttttgaaag actgtaaagc cttttttgat
    30421 gtgttctgtt tttggttttg aagttctacg atagttagac atacattctc tcctttgatt
    30481 atgatttatt atactctgtt tctttaaaaa aatcttaaaa aaagagaaat ttccctttct
    30541 tgtcgcaagc tccgtttcat gatacaatag aggaagtgat tttagaaagc gtgagaaaca
    30601 tgatttactt tgataattca gcgacgacca agccttatcc tgaagccctt gaaacctata
    30661 tgcaggtcgc ttcaaaaatt ttaggaaacc catctagtct ccatcgtttg ggagaccaag
    30721 caacacgaat cttagatgct tctcgccaac agattgcaga tttaatcggt aagaaaagcg
    30781 atgaaatctt ctttacctcg ggtggaacag aaggggataa ctggcttatc aagggtgtgg
    30841 cctttgaaaa agctcagttt ggcaagcaca tcattgtttc agccattgaa catccagcag
    30901 tcaaagagtc agccctctgg ttgaaaagtc aaggatttga agtggatttt gctccagttg
    30961 ataagaaagg cttggtcgat gttgaggcgt tagcaggttt gatacggcat gatacaatcc
    31021 tcgtttccat catggctgtg aacaatgaaa tcggctctat ccaacctatt gaggctattt
    31081 cagaattctt ggcagacaag ccgactattt ccttccacgt tgatgcggtt caggcgcttg
    31141 ccaaaattcc gactgaaaag tatctgacag aacgggtgga ttgcgcgact ttctctagtc
    31201 acaagttcca cggggttcga ggtgttggct ttgtctatat caaatctggc aagaagatta
    31261 cacctcttct tacaggtggt ggccaggagc gagattatcg ttcgacaact gaaaatgtgg
    31321 cagggattgc agcgacagcc aaggccctcc gtttgtctat ggaaaagcta gatatcttta
    31381 ggagcaagac tgggcagatg aaggcagtga ttcgccaagc tcttctgaac tatccggata
    31441 tttttgtctt ttcagatgag gaaaactttg cacctcatat tctgactttt ggaatcaaag
    31501 gtgttcgagg tgaagtcatc gttcacgcct ttgaagacta tgatattttc atctcaacaa
    31561 cctcagcttg ttcatctaag gcaggaaaac cagccggtac cttgattgcc atgggagtgg
    31621 acaaagataa ggccaagtca gctgtgcgtc ttagcctaga cttggaaaat gatatgagtc
    31681 aggtcgagca gtttttgacc aagttaaaat tgatttacaa tcaaactaga aaagtaagat
    31741 aggagcattc atgcagtatt cagaaattat gattcgctac ggagagttgt caaccaaggg
    31801 taaaaaccgt atgcgtttca tcaataaact tcgtaataat atttcggacg ttttgtctat
    31861 ctatacccaa gttaaggtaa cagcagatcg cgaccgtgcc cacgcttacc tcaatggagc
    31921 tgattacaca gcagttgcag aatctctcaa acaagttttt ggaattcaaa acttttctcc
    31981 tgtttataag gttgaaaaat ctgtagaagt tttgaagtct tctgtccaag agattatgcg
    32041 ggacatctac aaggaaggta tgacctttaa gatttctagc aagcgtagcg accacaactt
    32101 tgaacttgat agtcgtgaac tcaaccaaac acttggaggg gctgtattcg aagccattcc
    32161 aaatgtgcaa gttcaaatga aaagtcctga catcaatctt caggtggaga ttcgtgaaga
    32221 agcagcctat ctttcttatg aaaccattcg tggggctggt ggtttgccag ttggaacttc
    32281 aggtaaaggg atgctcatgt tgtcaggagg gattgactca cctgtagcag gttatcttgc
    32341 tcttaagcgt ggggtggata tcgaggcagt tcactttgct agtccaccat atactagtcc
    32401 tggtgccctc aagaaagcgc aggacttgac ccgtaaattg accaagtttg gcggaaatat
    32461 ccagtttata gaggtgcctt tcacagagat tcaagaggaa atcaaagcca aagcgccaga
    32521 agcttatttg atgactctaa ctcgtcgctt tatgatgcgg attactgacc gtattcgtga
    32581 ggtacgaaat ggtttggtta tcatcaatgg ggaaagtcta ggtcaagtag ccagccaaac
    32641 ccttgaaagt atgaaggcta tcaatgctgt taccaacact cccatcattc gtcctgtggt
    32701 taccatggac aagttggaaa tcattgacat cgcccaggaa atcgatacct ttgacatttc
    32761 aatccaaccg tttgaagact gttgtaccat ttttgcacca gatcgtccaa aaacaaatcc
    32821 taaaattaag aatgcggagc agtacgaagc gcgtatggat gttgaaggct tggttgagcg
    32881 agcagtggct ggaatcatga ttactgaaat cacacctcaa gccgaaaaag atgaagttga
    32941 tgacttgatt gacaatctgc tctaattcag aaaatccaaa agaatagcga aaatcagtaa
    33001 aaaaagttag ttttttctct aaaaacaggt aaaaaactaa ctttttttat ttttatgata
    33061 taatgatata aaattttgaa tatagagagt tttctgacaa tgaatcaatc ctacttttat
    33121 ctaaaaatga aagaacacaa actcaaggtt ccttatacag gtaaggagcg ccgtgtacgt
    33181 attcttcttc ctaaagatta tgagaaagat acagaccgtt cctatcctgt tgtatacttt
    33241 catgacgggc aaaatgtttt taatagcaaa gagtctttca ttggacattc atggaagatt
    33301 atcccagcta tcaaacgaaa tccggatatc agtcgcatga ttgtcgttgc tattgacaat
    33361 gatggtatgg ggcggatgaa tgagtatgcg gcttggaagt tccaagaatc tcctatccca
    33421 gggcagcagt ttggtggtaa gggtgtggag tatgctgagt ttgtcatgga ggtggtcaag
    33481 ccttttatcg atgagaccta tcgtacaaaa gcagactgcc agcatacggc tatgattggt
    33541 tcctcactag gaggcaatat tacccagttt atcggtttgg aataccaaga ccaaattggt
    33601 tgcttgggcg ttttttcatc tgcaaactgg ctccaccaag aagcctttaa ccgctatttc
    33661 gagtgccaga aactatcgcc tgaccagcgc atcttcatct atgtaggaac agaagaagca
    33721 gatgatacag acaagacctt gatggatggc aatatcaaac aagcctatat cgactcgtcg
    33781 ctttgctatt accatgattt gatagcaggg ggagtacatc tggataatct tgtgctaaaa
    33841 gttcagtctg gtgccatcca tagtgaaatc ccttggtcag aaaatctacc agattgtctg
    33901 agattttttg cagaaaaatg gtaagttaag aaaggaaaaa acgaaatgca tattgaacat
    33961 cttagccact ggagtggtca tcttaaccgt gaaatgtacc ttaaccgtta tggacatggt
    34021 gggattccag ttgtggtctt tgcttcatca ggtggtagtc acaacgaata ctatgatttt
    34081 ggcatgattg atgcctgtgc ttcctttatc gaggaaggcc ttgtccagtt ctttacccta
    34141 tctagtttgg atagtgagag ctggttggct acttggaaaa atgctcatga ccaagcggaa
    34201 atgcaccgtg cctacgaacg ttatgtgatt gaggaggcca ttcttttatc aagcacaaga
    34261 caggttggtt tgatggcatg atgacgacag gttgctctat gggagcctat catgcactca
    34321 atttcttcct ccagcatcca gatgtcttta ccaaagtgat tgctctcagt ggtgtttacg
    34381 acgcacgttt ctttgtcggt gattactaca acgatgatgc tatttaccaa aactcgccag
    34441 tagattatat ttggaaccaa aacgacggct ggtttattga ccgttaccgt caggcagaga
    34501 ttgtgctgtg tacggggctt ggagcctggg aacaagatgg tttgccatcc ttttacaagc
    34561 tcaaagaagc ctttgacaag aaacaaattc cagcctggtt tgctgaatgg ggacatgatg
    34621 tcgcccatga ctgggaatgg tggcgtaaac aaatgcctta tttcctcggt aatctctatt
    34681 tataaaagga gttacctatg aattaccttg ttatttctcc ctactatcca caaaactttc
    34741 aacagtttac catcgaacta gctaataaag gcatcacagt cttgggaatt ggtcaagagt
    34801 cttacgagca attggatgag cccttgcgca atagcttgac cgagtatttt cgtgttgata
    34861 atcttgagaa catagatgaa gtcaaacgtg cagttgcttt tctcttttat aaacatggtc
    34921 caattggccg catcgagtct cacaatgaat actggcttga gctagacgca acactcagag
    34981 aacaattcaa tgtttttggt gccaaaccag aggatctcaa aaagacgaaa tataagtctg
    35041 aaatgaagaa acttttcaaa aaagcaggtg ttcctgtggt acctggagct gttatcaaga
    35101 cggaagcaga tgttgatcaa gcagtgaaag aaatcggtct tccaatgatt gccaaacctg
    35161 ataatggagt gggagcagcc gcaaccttta aacttgagac agaagacgat atcaatcact
    35221 tcaagcaaga atgggaccat tcaacccttt atttctttga aaaatttgtc acttccagcg
    35281 aaatctgtac ctttgacggg ctcgtggaca aggatggaaa gattgtcttc tcaacaacct
    35341 ttgactacgc ctatacaccg cttgacctca tgatttataa gatggacaat tcttattatg
    35401 tgctcaagga tatggatcct aaactgcgca agtatgggga agcaattgtc aaagaatttg
    35461 gtatgaaaga acggtttttc catattgagt tcttccgtga gggggacgat tatattacca
    35521 tcgagtacaa taaccgccct gcaggtggtt ttaccattga tgtttataac tttgctcatt
    35581 ccttggacct ttatcgtggc tatgcagcta ttgtcgcagg agaggagttc ccggcgtcag
    35641 actttgaaac tcagtattgt ttggctactt ctcgccgtgc aaatgctcac tatgtttatt
    35701 cagaagagga tttgcttgcc aaatatagcc agcagttcaa ggttaaaaaa gtcatgccag
    35761 ctgccttcgc ggaacttcaa ggagattacc tgtatatgct gaccactccg agtcgacaag
    35821 aaatggagca gatgattgca gatttcggac aacgtcaaga ataagaacta tcggattaag
    35881 gaaattaact cccttaatcc ttttgttttg tctgataaaa aataagagca tcccaacaag
    35941 gtagctatca taaaacttgt tcgataacta tttgaagcag gattaggtgg tcagaaatta
    36001 aattttaata tttcaattga gtcatagtat tgtgtttgcg tatccttaaa tcagctaaaa
    36061 ggatccatga cgacacctat acgatatagt tttcaagata ccaaacaagt ctattaatat
    36121 tcaatgaaaa tcaaagagca aactaggaag ctagccgcag gtttctcaaa acactgtttt
    36181 gaggttgtgg atagaactga cagagtcagt atcatatacc tacggcaagg tgaagctgac
    36241 gtggtttgaa gagattttcg aagagtataa aatattcagg tgacgcatag atatagttaa
    36301 ttgaagcttt gtttgaaatc tgataaaata atgatattac taagttttaa aaactaaaga
    36361 aaagggaaga tatgattaca ggcgaattaa aaaataaaat cgatcagctg tgggaaattc
    36421 tttggacaga aggaaacgca aatcctttaa caaatattga acagttgact tatctcttat
    36481 ttatgaaaga tttggatagt gtcgagcttg gacgtgaaag tgatgctgaa tttctaggga
    36541 ttccttatga gggagttttt ccaaaagata aacctgaata ccgttggtca acttttaaaa
    36601 atataggaga tgctcaggaa gtttatcgtt taatgactca ggagattttt ccgtttatta
    36661 aaaatctcaa gggggataca gatgatacag ccttttcacg atatatgcga gaagctattt
    36721 ttcaaataaa taaacctgct acgcttcaaa aggcaatttc tatcttagat gtttttccaa
    36781 ctaggggatt agatgtagat tttgataatg acaaacaaag tattactgat atcggagata
    36841 tctatgaata tctgttatca aaattgtcga ccgcaggtaa aaatggacag ttccgtacac
    36901 ctcgtcacat catcgatatg atggttgagt tgatgcaacc gactatcaaa gatatcatct
    36961 cagatcccgc tatgggttct gctggcttct tagtatctgc tagccgttac ttaaagcgta
    37021 agaaagatga atgggaaacc aatacagata atatcaatca ttttcataat cagatgtttc
    37081 atggaaatga tacggatacg actatgttga gacttggggc gatgaacatg atgctacatg
    37141 gagtagaaaa tccacaaatc agttaccttg actcgctgtc tcaagataat gaagaagccg
    37201 ataaatatac tttggtttta gcaaatcctc cttttaaggg ctcacttgac tacaattcaa
    37261 cctctaatga ccttcttgca accgtaaaaa ccaaaaaaac agaattactc tttctttctc
    37321 ttttcttgcg aactttaaaa ccaggtggac gagcagcagt tatcgtacct gatggtgtcc
    37381 tttttggttc gtctaaagct cataaaggaa ttcgtcagga aattgtagag aatcataagc
    37441 ttgatgctgt aatctcaatg cctagtggtg tgttcaagcc ttatgctgga gtttcaactg
    37501 ccattctcat ctttacaaaa actggtaatg gtggtactga caaagtctgg ttttacgata
    37561 tgaaagcgga tggtttaagt ttggatgata agcgacaacc gattagcgac aatgatattc
    37621 cagatattat cgaacgcttt catcatcttg aaaaagaagc agaacgtcag agaacggatc
    37681 aatctttctt tgttccagtt gctgagataa aggaaaatga ttatgatttg tctatcaata
    37741 aatataaaga gattgagtat gaaaaagttg agtatgaacc aacagaggtc atcttaaaga
    37801 aaatcaatga tttagaaaaa gaaattcaag ctggcttggc tgaattagaa aaattactca
    37861 agtagagagg tggctgtatg aaaaaagtga agttggggga agtcttatct ctaaaaaaag
    37921 gcaagaaagc cactgtactt gctgaacaaa caactctaag ccaacgttat attcaaatag
    37981 atgatttaag aaataataat aatttaaaat tcactgaaag tttaaatatg actgaagcac
    38041 tcccagatga tattctgata gcatgggatg gagctaatgc aggaacagtt ggttatggat
    38101 tatcgggagc tgttggtagt acaattacgg tcttaaaaaa gaatgagcga tacaaagaaa
    38161 aaattatatc agattacttg ggagtctttt tggaaagtaa atcgcagtat ttacgagaac
    38221 attcaacagg tgcaacaatt cctcatttaa acaagaatat attacttgat ttacaattag
    38281 aattgctagg tatcgaagaa caagagaaca ttatctgtat tcttaatacg attaaaaggc
    38341 ttattactaa aagaaaattg cagttagatg aactaaactt gctcgtcaaa tcccgattta
    38401 acgagatgtt tggggatgtt attctaaatg aaaaagaatg gaaagttagc aaatggaacg
    38461 agattctaac aataagaaat ggtaaaaatc aaaaacaggt tgaagatgct gatgggaaat
    38521 ttcctattta tggaagtggg ggaattatgg gatatgctaa agattggata gtgaagaaaa
    38581 attcagttat tattggacgt aaaggaaata taaataaacc tattttagtt agagaaaatt
    38641 tttggaatgt agatacagca tttggattag agcctgtttt agaaaaaata aactcagaat
    38701 atttattcta tttttgtcaa ttatacaatt ttgagaagtt aaataaggct gtaacaatac
    38761 ctagtttaac taaatcagat ttattaaata tttccatccc cctcccccca ctagccctcc
    38821 aaaatgagtt cgcagacttt gtagccctgg tcgacaaatc acaatttgct tgtgagatag
    38881 ctataaaagt gtggagaaat agcttgaaat ttagtataat atagctaaac tatttgttta
    38941 aagtgagaaa aaaatgggaa attttagctt tcttttaaaa aatgacgaat atgaatcttt
    39001 ttcaaaacct tgcattgaag ctgagaatat gattgctaca tcaactgtgg ctactgcctt
    39061 tatggcgcgt cgtgctttag agcaggctgt ccattggata tatagtcacg attcatattt
    39121 agaagctccc tatcgtgcta ctctatcttc tttagtatgg gatgatgatt ttagggatat
    39181 cgtagattct gaactccaca agcagatagt tctgttgatt cggtggggaa accatgctgc
    39241 tcatggtggt gaaattaagg aacgagaagc gattttagct ttgcatcatt tgtatcagtt
    39301 tgttaatttt atcgattatt gttacagcaa tgagtttgtg gagcgttatt ttgatgagaa
    39361 gtgcttacca ctttcagcaa acatcaaata ccgagaaact ccacaatcta tgataaagtt
    39421 acaagacagt ttaccagaac tgcctgattt tcatgaacag atggctgctc agtccgtaga
    39481 agttcaagag acttatactg aaaaacgtga gactgcagcg caacggcaag atgtgccttt
    39541 ccatattgat caattatctg aggcagagac aagaaagctc tttattgata tcgatctccg
    39601 tttagcagga tggatatttg aagaaaactg tcgtgttgag atagccgttg atggtctcaa
    39661 gcacggttca ggaattggtt actgtgacta tgtactttat ggtaaaaatg ggaaaatttt
    39721 agcgattgtg gaggctaaaa aagcctctgt caatccagaa gtaggggaag tacaggtcaa
    39781 agaatatgct gaagctttgg agaaacatat cggctatcag ccaatttgct ttattacaaa
    39841 tgggttgaag cactatatac ttgatggtcc gaaccgccgc cagattgcag gcttttactc
    39901 tcaagaagaa ttgcaattag tgatggatag acgtcatctt caaaaaccgc ttgaggatat
    39961 ttctagtaaa attagggacg atatttccgg gcgtcactac caaaaacatg ccattgcaag
    40021 cgtttgtgaa gctttctctg atcatcgtag acaggcactt ttggttatgg caactggggc
    40081 ggggaaaact cgtacagcag tttctctagt tgatatctta tcacgtcata actgggtaaa
    40141 aaacgttctc ttcttagccg atagaacttc cttggttaag caagcatatg attcgtttag
    40201 aaaattactc ccagatcttt ccgtttgtaa cttcttagaa gataaagaag gagctcaatc
    40261 aagtcgaatg gtcttttcaa cttatccgac catgattgga gcgattagtg gtcaagaaga
    40321 agtaaatcaa cgccctttta ctgttgggca ttttgacctt atcataattg acgaatctca
    40381 ccgttctatt tatcagaaat acaagtccat ttttgattat tttgatgcaa ggattgtagg
    40441 cttaacagct actccgcgtc aagatttaga taaaaacacc tatggattct ttaatttgga
    40501 gaatggggtt ccaacatatg catatgattt ggaagaggct gttaaagacg gatatttagt
    40561 agcctatcat tctatcgaaa ccaaactgaa actacctacg gatggtctac attatgatga
    40621 tttgtccgaa gaagaaaagg aacattttga tagcaaattt gaagacgata gctgtgaaaa
    40681 agatattgat gggagtgtgt ttaattcctt tattttcaat aaaagtacag tagaaattgt
    40741 tttaaatgaa ctcatgacaa gaggaattca gacagcctcg ggtgatgaaa ttggtaaaac
    40801 tattattttt gctaaaaatc atgaccatgc ggaatatatc agaggtattt ttaacaaccg
    40861 ctatcctgaa aaagggagcg actatgctca ggtgattgat tatagtatta agcattatca
    40921 gaccttgatt gatgatttta aaattaagga gaagtatcct caaattgcga tttctgtcga
    40981 tatgttagat acaggtattg atgtaccaga ggttgttaat ttagtcttct tcaagaaagt
    41041 acgctctaaa actaagtttt ggcagatgat tggtcgagga acccgtctat gtaaagattt
    41101 atttggacct gagcaggata aggaaaactt cttggtattt gattatgggg acaattttga
    41161 ttattttcgt gcagatccaa gagatggaga gggtcgtcac attgtttcgc tgactcagcg
    41221 tttatttaat atcaaagtgg acttgattcg agaacttcag ggactccaat accaagaaga
    41281 tcagtttgcg agagcatacc gtcagcagct tgtctcggaa cttcaaggtc gtatagagag
    41341 cttaaatgag ttggacttca gggttcgtat ggttttagat acagtttata gctataggaa
    41401 attggaaagt tggcagaatc taactgctgt tacaagtgaa accattcaaa aaaatctctc
    41461 tccgctttta tttgatgaag ataaagaaga tgagatggcg aggagatttg atttgtggtt
    41521 gcttcatatt cagttggggc aactgacagc taaatcttcc actgttcata tttcccaagt
    41581 gatgaagacg gctagagctc tttctgctat tggcaatatc ccgcaggttt ttgagcaggc
    41641 tgaaattatg gctctttgtc aactgtagtg ggttgaaaaa aagctaagct tgagaaagga
    41701 caaattttgt cctttctttt ttgatattca gggcgataaa aatccgtttt ttgaagtttt
    41761 caaagttccg aaaaccaaag gcattgcgct tgataagttt gatgagatta ttggtcgctt
    41821 ccagtttggc attagaatag tgtagttgaa gggcgttgac gattttctct ttgttcttta
    41881 gaaaggtttt aaagacagtc tgaaaaagag gatgaacctg cttcagattg tcctcaatga
    41941 gtccgaaaaa tttctcaggg tctttgttct gaaagtgaaa aagtaagagt tgatagatct
    42001 gatagtggtg tttcaagtct tctgaatagc ttaaaatctt gtcaagaatt tctttatttg
    42061 ttaagtgcat gcgaaaagta gggcgataaa aacgtttatc gctcaattta cgactatcct
    42121 gttggatgag tttccagtaa cgcttgatag ccttgtattc atgagatttt cgttcaaact
    42181 gattcataat ttgaacacga aaacgactca tggcacggct gagatgttgg ataatatgga
    42241 aacgatctag aacgatttta gcacacggaa aaagctgttt agccaagtca tagtaaggac
    42301 taaacatatc catcgtaatg attttcactt gacaacgaac ggctctatcg tagcgaagaa
    42361 agtgatttcg gatgacagct tgtgttctgc cttcaagaac agtgataata ttaagattat
    42421 caaaatcttg cgcaatgaaa ctcatctttc ccttagtgaa ggcatactca tcccaagaca
    42481 taatctttgg aagccgagaa aaatcatgct caaagtgaaa gtcattgagc ttgcgaatga
    42541 cagttgaagt tgaaatggcc agctgatggg caatatcagt catagaaatt ttttcaatta
    42601 acttttgagc aattttttgg ttgatgatac gagggatttg gtgatttttc tttaccaggg
    42661 gagtctcagc aaccatcatt tttgaacagt gatagcactt gaaacggcgt tttctaagga
    42721 gaattctagt aggcatacca gtcgtttcaa gataaggaat tttagaaggt ttttgaaagt
    42781 catatttctt caattggttt ccgcactcag ggcaagatgg ggcgtcgtag tccagtttgg
    42841 cgatgatttc cttgtgtgaa tccctattga cgacatctat aatttggata tttgtgtctt
    42901 tgatatcgag tagttttgtg ataaaatgta attgttccat atgaatcttt ctaatgagtt
    42961 gtttggtcgc ttttcattat agatcttatg ggactttttt tctacaataa aataggctcc
    43021 ataatatcta tagtggattt acccactaca aatattatag agccgaaatt atcaggaaag
    43081 tacaggagcc tgaattttgg aaagaagtta acttgtctga tttggaaaaa attcgtcttg
    43141 ctattcgaga tttattacag tttttggata aaacagaccg taaaccctac tatgttaact
    43201 ttgaagatcg tatactctcc actgttcacg agaccacagc atttttgcag gtcaacgatc
    43261 ttcggtctta caatgaaaaa gttgagcatt atttgaaaac tcatctggat gaggagtcca
    43321 tttctaagct ataccataat aaaaagttga catctgatga tatgcttgca cttgaaaaat
    43381 tgctttggga aaaattaggt agtaaagcag actaccaaag tcattatgaa aataaggcaa
    43441 ttccgagatt ggttcgtgag attattggct tagatagaga gtctgccaat cgtattttct
    43501 ctaaattttt gtcggatgag aatcttaatg ccaggcagat ttcatttgta aaattgattg
    43561 tagactacat tgtagaaaat ggttttttag agacgaaagt gttaacgcaa gagccgttta
    43621 aatcttatgg ttctgttcaa ctactcttcc aacaccaact accagtactt cgtaatattg
    43681 ttcaaatcat tgaacttatc aataatcgag ctggagaagc ggcttaaatt ctaaagtgat
    43741 tgccatgctg agactcattt aaaattaaaa agagtagaaa tttatgctat atatgagaag
    43801 ttttattagg aagaatgtca tcgttttcct agaatacagt atcagttgtt aagtggttga
    43861 taaatttcaa agtagatact tgtaccacga tgtttgttga tcgagttatt aacaaaagag
    43921 ctactttgat tttaacccaa atcattcata cctctctcaa ctagatgtaa cttacaaaac
    43981 ccctgacctc atgagccact ttcttcctcc tcatgaggtc agttttactt tctgctgttc
    44041 cagtatcgtt tttcctcgct agatttcctc aaaagggcag actcctccct tggtgcgtca
    44101 cacgattttt tcatctcgac tgttctttaa tgcatcatta acgacgcttt tcttccaggt
    44161 ggttcataag gaacaggaag attcaggttg acttttctaa tcctagaata aagtgctgaa
    44221 aacaattcgg aataggcata gagactagac aatttgagga gctgcttgcg tcctgttcga
    44281 acacattttc ctaccacgtg aagaaaaaga tggcggaagc gtttgattgt taaagtttgg
    44341 aagtcacctc cagctagatg tttgagaaaa agatagagat tgtaggcgat acagctcatc
    44401 atcatacgaa cttcgttttt gattaaggtt gaactatccg ttttatcgcc aaaaaatccc
    44461 tccttcatct ccttgatgaa attctcggct tgaccacgtc cacgataaag ctgaaactgg
    44521 tcttggcttg ttccactcgt catatttgta acgagagaaa taacatcgta gaacaagttt
    44581 ccttcttttc gttcagagaa ctggcagaca cgacgcttgt gcgaccaaga tcctgcttga
    44641 tagagagttt ctgagtaggc ggagtggggc aagatggtta agtcctcatc ctgtgggcaa
    44701 gggagggaaa ggtctccaag acggctcaga acagtatttt tcttgagttt tatgagttag
    44761 tattgccctg ttttttcaat taaatcgtat aatttggggg tcgcaaagcc actatccatt
    44821 cgaaagagaa gttgattaaa ccgttctaaa acaggtgtga taaagctgtc tgcctcttca
    44881 gaacaataac gattaccagg acgaagctgg gcattgaaac aataacctgt cttcccctcg
    44941 aaagcataaa gaggatgata gccatgagca cgatagtggg cgttataagc aacaccttct
    45001 tgcttgccat aagttgtgaa atgggtagaa tcgatatcta caatgagttg gtttagctgg
    45061 tgaaactgta aaaagaattc gaccaattca aggttgaggc atcgcaaact atggactgtt
    45121 tcctcgtcag ttctggaaag aaaacgggat aaggttggct gtgaagcaag ctgccctcct
    45181 tccaacaatt ttggaaagta ggcatcagct gacaattctt tacaagcata gtccgttcca
    45241 tagcctgtta acagttgaaa gaggaactgg acaaggatat ctgaatccga ataacgacag
    45301 tagcggcgtt ggtcattcgt tactaaatac ttagaaatcc gctcttttag tttcaactgg
    45361 gaaaaaagtt cctgaaaaaa gataagacca ccatactggg ttaaatgacc tccatcgaaa
    45421 gatagttggt aaaaagactt gttttggaag tgatgatttg gtaaactgtt catgtgagtt
    45481 tcctttcttt ttgtgttttt ttctacactt ataccataaa ggggaaattc ttttttgtct
    45541 agtaaaaaac acccattggg tgaaaaaaga aaccatacag gatctaagct aaggcaagga
    45601 ttctggatgg tttttagatt aggggtgaat aattggggtt ttaaagaaat agaaaacaaa
    45661 aagccgagca agaattcaat tgcaggagaa aatgaaataa tactcaatga aaatcaaaga
    45721 gcaaactagg aaactagctg caggctgctc aaaacactgt tttgaggttg tagataagac
    45781 tgacgaagtc agctcaaaac atggttttga ggttgtagat gaaactgacg aagtcagtaa
    45841 ccatacctac ggcaaggcga cgttgacgcg gattgaagag attttcgaag agtataaatc
    45901 ttcctaggat aaagcaaaga gcctgggaca aaatagttct cgaccacaaa aaagctagag
    45961 atttccaatt gtggaacttt agctttttaa ttttgagtcg ttctcttatt gtattttagg
    46021 aggttattgg ccataagtac caatcccatg tcaattctca cttgacgctt gcccctcaga
    46081 ttacatctct tgtaacccaa acaagccttt atctgcccaa agacaggtga cattctttag
    46141 ctttcaagtt ttgatagcct tcgttcatat acagtccctt ttgaggggct gattcaggtt
    46201 cgtcggcgta gtaaaccttg atttcttgtt taaagtctgt ctgtgttttc tgatgtttgg
    46261 tatggtgaaa acgataatac cagccatcag gatgtgtata gctatcctcc ttgtcattat
    46321 agtaccaatt cgctaagttt ctagctgact gtttatagcc tctcttctgt tccttatcaa
    46381 acatggcata tttaatcaga tggtttacct ccttttcatc taactaaagg agaagcaata
    46441 tggctgaacg attttgggag aacttgtcca ttattttggc tga
//
LOCUS       DAVAZT010000009        46272 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVAZT010000009 DAVAZT010000000
VERSION     DAVAZT010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46272
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.009"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(405..1751)
                     /gene="gdhA"
                     /locus_tag="VQT45_000454"
     CDS             complement(405..1751)
                     /gene="gdhA"
                     /locus_tag="VQT45_000454"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HET2358830.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            2092..2826
                     /locus_tag="VQT45_000455"
                     /pseudo
     CDS             2092..2826
                     /locus_tag="VQT45_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2823..3041
                     /locus_tag="VQT45_000456"
     CDS             2823..3041
                     /locus_tag="VQT45_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2358831.1"
                     /translation="MSISPRFEALEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     TAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(3098..3382)
                     /locus_tag="VQT45_000457"
     CDS             complement(3098..3382)
                     /locus_tag="VQT45_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HET2358832.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(3436..4371)
                     /locus_tag="VQT45_000458"
     CDS             complement(3436..4371)
                     /locus_tag="VQT45_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HET2358833.1"
                     /translation="MEICQQILEKIKEYNTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNVTDAETAAIVGAPGRIDSVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            4475..4918
                     /locus_tag="VQT45_000459"
     CDS             4475..4918
                     /locus_tag="VQT45_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HET2358834.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            5034..5300
                     /locus_tag="VQT45_000460"
     CDS             5034..5300
                     /locus_tag="VQT45_000460"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HET2358835.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSYILKRSRDYQDQNIK"
     gene            5297..5671
                     /gene="crcB"
                     /locus_tag="VQT45_000461"
     CDS             5297..5671
                     /gene="crcB"
                     /locus_tag="VQT45_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET2358836.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYFSLV
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            5665..5994
                     /gene="crcB"
                     /locus_tag="VQT45_000462"
     CDS             5665..5994
                     /gene="crcB"
                     /locus_tag="VQT45_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET2358837.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            6113..6460
                     /gene="rplS"
                     /locus_tag="VQT45_000463"
     CDS             6113..6460
                     /gene="rplS"
                     /locus_tag="VQT45_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HET2358838.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            6503..6574
                     /locus_tag="VQT45_000464"
     tRNA            6503..6574
                     /locus_tag="VQT45_000464"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6536..6538,aa:Arg,seq:cct)
     gene            complement(6741..7739)
                     /locus_tag="VQT45_000465"
     CDS             complement(6741..7739)
                     /locus_tag="VQT45_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HET2358839.1"
                     /translation="MNFFSKLFNLKQNNHNRDTNSDCNNFYLNELECGLTPGQLILID
                     WTQKTGRNYNFPRYFKYSLQIDPESTHNQLYKLGYFTKNKTLSYLTVVELKTILSKHN
                     LATSGKKAELITRIINNVNIDNLDIPFEFKLTKEAQNLIIEHSDYIKAYYDKDISMED
                     YCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNTRKAQGRHLEQEGNIKHA
                     LIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQTLMESLSDDDYDFAFDE
                     ALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKYECYSPLNNLELDDFE"
     gene            complement(7782..8588)
                     /gene="yidA"
                     /locus_tag="VQT45_000466"
     CDS             complement(7782..8588)
                     /gene="yidA"
                     /locus_tag="VQT45_000466"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HET2358840.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRPMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(8601..9905)
                     /locus_tag="VQT45_000467"
     CDS             complement(8601..9905)
                     /locus_tag="VQT45_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HET2358841.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTVTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPVENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKNFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLTSMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESQNPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            9977..10354
                     /locus_tag="VQT45_000468"
     CDS             9977..10354
                     /locus_tag="VQT45_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HET2358842.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELMMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            10445..10777
                     /locus_tag="VQT45_000469"
     CDS             10445..10777
                     /locus_tag="VQT45_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HET2358843.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            10789..12360
                     /gene="ffh"
                     /locus_tag="VQT45_000470"
     CDS             10789..12360
                     /gene="ffh"
                     /locus_tag="VQT45_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HET2358844.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(12555..13838)
                     /locus_tag="VQT45_000471"
     CDS             complement(12555..13838)
                     /locus_tag="VQT45_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HET2358845.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(14141..14854)
                     /gene="rsmG"
                     /locus_tag="VQT45_000472"
     CDS             complement(14141..14854)
                     /gene="rsmG"
                     /locus_tag="VQT45_000472"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HET2358846.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            14948..15508
                     /locus_tag="VQT45_000473"
     CDS             14948..15508
                     /locus_tag="VQT45_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HET2358847.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTSEEEKSVPKVDFSGLGD"
     gene            15510..16409
                     /gene="htpX"
                     /locus_tag="VQT45_000474"
     CDS             15510..16409
                     /gene="htpX"
                     /locus_tag="VQT45_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HET2358848.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(16453..18012)
                     /locus_tag="VQT45_000475"
     CDS             complement(16453..18012)
                     /locus_tag="VQT45_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2358849.1"
                     /translation="MHYRHSRKGNSMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQSLAYIPQKVPEDLKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKTAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLAQELQLTVRGQEKIGIIGPNGVGKSTLLAKLQQLLNDKREISLGFMPQDYHK
                     KLQLDLSSIAYISKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(18251..18568)
                     /locus_tag="VQT45_000476"
     CDS             complement(18251..18568)
                     /locus_tag="VQT45_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET2358850.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSPLIGLGSLKLNDQARTAWRNYDKIHYEHVKHVLSLYGPV
                     FGF"
     gene            18747..19289
                     /locus_tag="VQT45_000477"
     CDS             18747..19289
                     /locus_tag="VQT45_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HET2358851.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            19289..19918
                     /gene="nth"
                     /locus_tag="VQT45_000478"
     CDS             19289..19918
                     /gene="nth"
                     /locus_tag="VQT45_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HET2358852.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            20129..20650
                     /gene="pyrR"
                     /locus_tag="VQT45_000479"
     CDS             20129..20650
                     /gene="pyrR"
                     /locus_tag="VQT45_000479"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HET2358853.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            20669..21592
                     /locus_tag="VQT45_000480"
     CDS             20669..21592
                     /locus_tag="VQT45_000480"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HET2358854.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGKFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            21642..22721
                     /gene="carA"
                     /locus_tag="VQT45_000481"
     CDS             21642..22721
                     /gene="carA"
                     /locus_tag="VQT45_000481"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HET2358855.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            23033..26209
                     /gene="carB"
                     /locus_tag="VQT45_000482"
     CDS             23033..26209
                     /gene="carB"
                     /locus_tag="VQT45_000482"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HET2358856.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(26484..27293)
                     /locus_tag="VQT45_000483"
     CDS             complement(26484..27293)
                     /locus_tag="VQT45_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET2358857.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDQFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNIPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(27295..28098)
                     /locus_tag="VQT45_000484"
     CDS             complement(27295..28098)
                     /locus_tag="VQT45_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET2358858.1"
                     /translation="MKQLTVEDAKQIELEILNYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPMDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRLVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSATFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(28108..29595)
                     /gene="tacF"
                     /locus_tag="VQT45_000485"
     CDS             complement(28108..29595)
                     /gene="tacF"
                     /locus_tag="VQT45_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HET2358859.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGDILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SEASLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            29931..30638
                     /locus_tag="VQT45_000486"
     CDS             29931..30638
                     /locus_tag="VQT45_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HET2358860.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDSIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            30643..31665
                     /locus_tag="VQT45_000487"
     CDS             30643..31665
                     /locus_tag="VQT45_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET2358861.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            31682..32551
                     /gene="licA"
                     /locus_tag="VQT45_000488"
     CDS             31682..32551
                     /gene="licA"
                     /locus_tag="VQT45_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HET2358862.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            32541..33419
                     /locus_tag="VQT45_000489"
     CDS             32541..33419
                     /locus_tag="VQT45_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HET2358863.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            33431..34120
                     /locus_tag="VQT45_000490"
     CDS             33431..34120
                     /locus_tag="VQT45_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HET2358864.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQNIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     HKLEEILKNEN"
     gene            34218..35066
                     /gene="dprA"
                     /locus_tag="VQT45_000491"
     CDS             34218..35066
                     /gene="dprA"
                     /locus_tag="VQT45_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HET2358865.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            35950..36993
                     /locus_tag="VQT45_000492"
     CDS             35950..36993
                     /locus_tag="VQT45_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HET2358866.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGHNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFYTESEEQ"
     gene            37160..39247
                     /gene="topA"
                     /locus_tag="VQT45_000493"
     CDS             37160..39247
                     /gene="topA"
                     /locus_tag="VQT45_000493"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HET2358867.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            39468..39827
                     /locus_tag="VQT45_000494"
     CDS             39468..39827
                     /locus_tag="VQT45_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HET2358868.1"
                     /translation="MRIIYLIIGFLSLTLAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQAYVADFRETKSIARERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            39920..40552
                     /locus_tag="VQT45_000495"
     CDS             39920..40552
                     /locus_tag="VQT45_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HET2358869.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            40596..41252
                     /locus_tag="VQT45_000496"
     CDS             40596..41252
                     /locus_tag="VQT45_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HET2358870.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVYMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            41271..42365
                     /locus_tag="VQT45_000497"
     CDS             41271..42365
                     /locus_tag="VQT45_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HET2358871.1"
                     /translation="MNFQLAKYSLLKRFLENIGFTTLEEYGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKILLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALVDKKQEITDADI
                     RALVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEFNATGQGSVEAIF
                     NAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNAAGLDFDVLKASA
                     IVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            42377..43414
                     /gene="leuB"
                     /locus_tag="VQT45_000498"
                     /pseudo
     CDS             42377..43414
                     /gene="leuB"
                     /locus_tag="VQT45_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            43411..43680
                     /locus_tag="VQT45_000499"
     CDS             43411..43680
                     /locus_tag="VQT45_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HET2358872.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKSKARRRVWRIPEKILLIL
                     AFTFGGFGAWLAGIIFHHKTRKWYFKIVWFLGMVTTLVALYFIWR"
     gene            43684..44043
                     /gene="leuD"
                     /locus_tag="VQT45_000500"
     CDS             43684..44043
                     /gene="leuD"
                     /locus_tag="VQT45_000500"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HET2358873.1"
                     /translation="MAGSSREYAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            44205..44773
                     /locus_tag="VQT45_000501"
                     /pseudo
     CDS             44205..44773
                     /locus_tag="VQT45_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019771122.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            44867..44932
                     /locus_tag="VQT45_000502"
                     /pseudo
     CDS             44867..44932
                     /locus_tag="VQT45_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849983.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            45095..>46272
                     /locus_tag="VQT45_000503"
     CDS             45095..>46272
                     /locus_tag="VQT45_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HET2358874.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELMSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     "
BASE COUNT        14079 a         8295 c         9912 g        13986 t
ORIGIN      
        1 aataatagag caactacagt agtagcttaa aaacatgatt aaatcgctat tcttaggagt
       61 agcggttttt ctttttgttt aatactcttt gaaaatctct tcaaaccacg tcagctttgc
      121 cttgccgtac tcaagtacag cctgcggctc gcttcctagt ttgctctttg attttcattg
      181 agtataaaaa gggttaagta agtatagtaa attgaaataa gatatgaaca aatcgattag
      241 aaaagtcaaa ttaatttcta gaagtatgtt agaaattggt ttgaattccg caatcaattt
      301 gttcagtttt tatttcattt cattttattt aattagattt tccaattttt taattcaagc
      361 taaaaatccc caatcgtagt gattgaggat tgagtaaata aatcttaaac aataccttgt
      421 gcaatcatgg catttgctac attttcaaag gcagcaatgt tagctcctgc aaggtagtct
      481 ttatcaagac cgtatgtttc tgaagtcgtt ttagctgtgt tgaagatgtt tgtcatgatg
      541 tctttgagac ggccatcaac ttcttcacga gtccatgaga ggcgaagact gttttggctc
      601 atttcaagag ctgaaacggc tacaccacca gcgttggcag cttttgcagg tccgtagaag
      661 ataccatttt ctttgtaaac tttgatggca tcaaggtcgc tcggcatgtt ggcaccttca
      721 gatacacaga taacgccttg agcaaccaaa cgtttagctg cttcaccgtt gatttcgttt
      781 tgagtggcac atggaagagc aatgtcatag tttccagcgt aagtccatac agtaccttcg
      841 tggtaggttg cagttgcttt ttcagctgca tactcagtca aacgagcacg acgtttttct
      901 ttaacatcaa ccaaaagatc gaagtcgata ccattttcat cgatgacata accatttgag
      961 tcagaaacag aaataacagt tgcaccgagt tcagttgctt tttgaagagc atattgagca
     1021 acgttaccag aacctgaaat aacgactttc ttaccagcaa agctgttacc gttagctttg
     1081 agcatttctt cagtatagta aaccaaaccg taaccagttg cttctggacg aatcaagcta
     1141 ccaccaaatc caagaggttt accagtcaag acaccagcat caaattggtt aagacgtttg
     1201 tattgaccgt aaaggtaacc aatttcacgt ccaccaacac cgatatcacc agcaggtacg
     1261 tcaagtgatg gtccgatgtg tttttgcaat tcagtcatga agctttggca gaagcgcatc
     1321 acttcagcat ctgttttacc tttaggatcg aagtctgatc cacctttacc tccaccgata
     1381 ggaagtccag tcaagacatt tttaaagatt tgttcaaatc cgaggaattt caagatccct
     1441 tggtttacag ttgggtggaa acgaagtcca cctttgtatg gtccaacagc tgagttgaat
     1501 tgaacacggt aaccacggtt tacttgaatt tttccatcac ggtcaaccca aggaacacgg
     1561 aaagaaacca cgcgctcagg ctcagtaata cgtgccaaga tattttcttc gatatactca
     1621 gggtgttttt caaatacagg ttctaaagtg ttgaaaaatt cttcaacagc ttggaggaat
     1681 tcagcctcgt gcccgttacg agctttcaca gtttcaaaca cgctttggat atattcttta
     1741 gcagatgtca tatcgttctc cttttattgt catattttat tacataagac attatagcag
     1801 aatttttttt cactgtaaag aaaaaacaga aattttctaa aaattctttc aattcagttt
     1861 ttggtttttt tgaaaataga taaaaaaacg aacgtttttc ttggaaatat ctttctcaaa
     1921 gacaaaatct taaagtatgg tatgctataa gaaaagaaaa tgtttagcaa ttcagaaatc
     1981 acttgttaat ttatccgtga tatgttagat ttgctagtaa aattatgacc attttggagg
     2041 aaagcaatat ttataccaga ctaaaatcaa aaatcattat ataatagtga tatgaaatca
     2101 actaaagaag aaatccaagc catcaaaaca cttttaaaag actctcgtac agctaaatat
     2161 cataaacgcc ttcaaatcgt tctatagtaa aatgaaacaa gaacaggaca aatcgattag
     2221 gacagtcaaa tcgatttcta acaatgtttt agaagtagag gtgtactatt atagattcaa
     2281 tacactatag actgtaatca aacaacgatt tggcgaaatg taaaaaatat gaggagttcg
     2341 gactcgactc tctccttcaa gaaacacgtg gtggtcgtaa ccatgcatat atgacagttg
     2401 aggaagagaa agcctttctt gcccgccatt tgaaggctgc agaggcagga gaatttgtta
     2461 caattgatgc cttatttcag gcttataaaa aggagtgtgg atgaacgcct ttttagaaga
     2521 gctttcacaa gcttatccag atgattatct tttactcgtt atggacaatg ctatatggca
     2581 taaatcaagt gccttaaaga ttccgactaa tattggcttt gcatttattc ctccatacac
     2641 accagagatg aacccattga acaagtgtgg aaagagattc gtaaacgtgg atttaagaat
     2701 aaagcctttt aaactttgga agatgtcatg aatcaactcc aagatgttat acaaggactg
     2761 gagaaggagg tgataaagtc catcgttaat cggagatgga ctagaatgct ttttgaaagc
     2821 agatgagtat aagtcctcgt tttgaagcct tggaacaggc cattgcctcc aaagatttgg
     2881 aaaaagtccg agaagctttt aagaaaatga attccacttg gaccatcaat gaaagtgtgg
     2941 ttcgtgacaa tagtacagct cattatggac gtgttgaaac agctatttcc ttcctgccta
     3001 gtagcatgga aaccgaacct acagatgagt ctggaacatg aaaacagcag ttgatttcaa
     3061 gaaacaaaaa agaacagtcg aaactgttct tttatcatta tttgagaccg tattttttgt
     3121 tgaaacgatc cacgcgtcca tctgcttgag tgaacttttg acgtccagtg tagaatgggt
     3181 gtgagtctga tgaaatttcc acacggatca atgggtaagt ttcgccttcg aactcaactg
     3241 tttcgttaga gcgttttgtt gaaccgctaa ggaattggta accagtagtt gtgtccatga
     3301 agacaactgg gcgatattct ggatggatat cttttttcat tttgcaatat ttcctttctg
     3361 ccatggtctc tttgcgagcc atagattgtt accatactag tctatcagat tctgaaaagt
     3421 ttggcaagta ttttatcagt ttttaagcaa gttttttaac ttttggtaga tgatttcatt
     3481 ttcttctagg ctataggaat tagcaccact tgctagaggg tggcctccac catcatgctc
     3541 cttggcgatt tcattgatag gatggatttt actgcgtaag cgaacgcggt agtggccatc
     3601 agcctgttcc acaaaaattc cccagagact aacactatca atacgcccag gtgcacctac
     3661 aatggccgca gtttcagcat cggttacatt gtattgtttc aagattttct gactcaggat
     3721 aacgcgagca gcaccatttt catccacttc cagatggtcg tagatgtagc cttgcagttt
     3781 agcaattttg tagctcatag tgtccatttt gcgagtgaga gccgcaaagt caaagttatg
     3841 ttctctcaaa taagcagcca ggcgaagagt ccgtgcagtg gtagaagggt agaggaagcg
     3901 acctgtatca ccgacaattc ctgcaaagag caactcagca tcgcgatctg ccaaggctag
     3961 ttgggttgtt tgggcaaata gggtaatcat ctcgctagcg ctacttgaac tagtatcgac
     4021 ccaagacagg tcaccgtata catcatcatt tggatggtgg tcaatcttaa tgagaaaatc
     4081 accttgacta tagcgcttat catcgatacg agcagtatta gctgtatcac agacgatgac
     4141 aagtgcgcct tggtaggctc tatcttcaac aagatccatc tcagccatcc aagtaagagt
     4201 tggttcatca aaaccgacgg ctttgatggt tttttctggg aaatgatgtt ccagcaaggc
     4261 tttcaatccc acctgacttc ccaaggcatc agggtctggt ttcatatgac gatgaatgat
     4321 aatggtgttg tattctttaa ttttttctaa aatttgttgg caaatctcca taaataacct
     4381 caattctttc tcatttcatt gtagcacaag aatttttatt tttaaaatga aaaagatgtg
     4441 atataatgga gaaagataaa ttgaggagga cgatatggca ttagcaaaaa ttgtatttgc
     4501 cagtatgacc ggtaataccg aagaaattgc agatattgta gcagacaaat tacgtgactt
     4561 gggcttggat gttgatgttg atgaatgtac aactgttgac gcttcagact tcttggaagc
     4621 agacatcgct atcgttgcga cctatactta tggtgatggt gaattgccag atgagatgat
     4681 ggacttctac gaagacctag cagatctcaa cttgaatggc aaaatctacg gagtggtcgg
     4741 ctcaggagat accttctacg atgaattctg taaggctgtt gatgactttg accgtgtctt
     4801 tgtgtcaaca ggagcagaaa aaggttcaga gtgtgttaaa gttgatcttt ctgccgagga
     4861 agaagatatt gaacgcttgg aacaattcgc agaagaattg gctgctaaag taggataagc
     4921 ataaaagtgc gctgatgtaa tcaatcagtg catttttctt atcgagagtt gggattttac
     4981 tagcctaatt gatggctttt tgatacaata attcaaataa aggaggagac tgtatggatt
     5041 tagatattat tcgtcaagaa atcgatcaaa tcgacgacca aattgtcaaa ctgttagaag
     5101 aacgaatgca tttagttgag ggggtggttg cttataagaa agcttcaggt aaaccgattt
     5161 tagatactaa gagagaagaa gttatttttg aaaaggttag gagtcgtgta gaggacaagc
     5221 gctatcagga gactattgtc gcgacttttt cgtacatact caaacgttcg cgtgattatc
     5281 aggatcaaaa tatcaaatga aaaaagaaca attttatccg ctaggaattt ttctagctgc
     5341 tatgttgggc ggacttgtcc gatatctagt ttccacctgg ttaccagcca gtccagactt
     5401 tccttggggc actctctttg tcaactatct gggaattttc tgcttgattt ttcttgtcaa
     5461 gggctatctg gtctataagg ggactagtaa gggcttgatt ttagcactgg ggacgggttt
     5521 ttgcggaggt ttaacaactt tttccagcct aatgcttgat actgtgaagc tgcttgatac
     5581 agggcgttat tttagtttag tcctgtattt gcttttgagt atcggtggag gcctgctttt
     5641 agcttactat ttggggagga agaaatggta atcgtctatc ttgcaatcgc ctgtggcttg
     5701 ggagcactcg tacggtattt cttttctcgc tataatcaag cttctaaatt gccactcgga
     5761 acgctcatag ctaatctttt aggttgtttt ttaattggag tattctacaa tcatgtagag
     5821 tctaaggaag tatatgctat tctagcaaca ggattttgtg gcggtttaac aactttttcg
     5881 accttgaatg acgaacttca aagactgcta agtgataaga aggtctttta ttcttacctg
     5941 actttgactt acataggtgg tttggttgcg atttttttag gaattttgct ataaatttct
     6001 ttactttttt ttagaaattt ggtaaactat atcttgtgtg taatggacgc acaaaaatac
     6061 agtttatccg ctgaggaaga ttcctcaaga ttgacaaaga taggagaata aaatgaatcc
     6121 attaatccaa agcttgactg aaggtcaact tcgtacagat atcccatcat tccgtcctgg
     6181 tgacactgtt cgtgtacatg cgaaagttgt cgaaggtaac cgtgaacgta tccagatttt
     6241 tgaaggtgtt gttattgcac gtaaaggtgc tggcatctct gaaaactaca cagttcgtaa
     6301 aatctctaac ggtgtaggtg ttgagcgtat cttcccaatc cacactccac gtgttgaaaa
     6361 aatcgaagtt gtacgttacg gtaaagtacg tcgtgcgaaa ttgtactact tgcgtgctct
     6421 tcaaggtaag gcagctcgta tcaaagaaat ccgtcgttaa ttcgactaaa aaactctgct
     6481 ttttcagcag agtttttatc tagctccctt agttcaatgg atataacaac tccctcctaa
     6541 ggagtagttg caggttcgat tcctgcaggg ggcatgtaat tagatatcaa agaagtttgt
     6601 caaagagtct ttgatattaa aagaacgcat aatatagggg attgtctcca taatattatg
     6661 cgttttatta ttgaaaaatt tgggcaatca tcagataaaa ttgagactat atcgagtata
     6721 taaatgtttg tatagtcaat ttattcaaaa tcgtcaagtt ctaaattatt taaaggacta
     6781 taacattcat atttctttaa gtaattgttt atttcttcag cagtggaacg aggtaaatta
     6841 actcttaaat agtcaatatc ttccttagat aaaaaatgat ttgcattcaa aattgagaag
     6901 cgaaataatg cttcatcaaa agcaaaatca taatcgtcat cagataatga ttccattaat
     6961 gtttgaatat gttttagtga gtagtcaggt atcgaatcgg gataatatac tggataatca
     7021 gtggctgaaa aattgttttc taatcctgaa atagtaatta tcaaagattc tatgtaatat
     7081 attaaagcat gtttaatatt accttcttgt tccaaatgtc ttccctgagc ctttcgtgtg
     7141 ttagataagc atccaaaatc tcctgataca gtattcctat gagcttgttt atttaagaga
     7201 ctccatttta tatcaccaaa agttgcttta aaagagatat tgtttttttc tttacaataa
     7261 tcttccatac ttatgtcttt atcatagtat gctttgatat agtcactatg ttcgataata
     7321 agattttgtg cttcttttgt tagtttaaat tcgaacggaa tatctaaatt gtcaatgtta
     7381 acattattaa ttattcttgt aattaattct gctttttttc cagaagtagc taaattatgt
     7441 ttagataata tagtttttaa ttctactact gtaagatatg ataaagtctt atttttagtg
     7501 aagtatccta atttgtataa ttgattgtgt gtagattcag ggtcaatttg aagagagtat
     7561 ttaaaatatc ttgggaaatt ataatttctc cctgtttttt gagtccaatc tatgagtatg
     7621 agttgcccag gagtaaggcc acattctaat tcgtttaggt aaaaattgtt acaatcagaa
     7681 tttgtgtctc tattatgatt attttgtttt aaattaaata gtttgctaaa aaaattcatt
     7741 ggattttatt gctaatcaat tcttattgaa aaatgatact tttacagtac ccatgttcgg
     7801 atggcatggg caacgccgga ttcgtcattt gttttggtga tgtatttggc gatttttttg
     7861 atttctggat ttccattttc catgacaacg gggtttccaa cgacttccag catgggacgg
     7921 tcattttctt catcaccgat tgccatggtt tcatctttgg tcaatccgag tttttcagcc
     7981 aagtgagtaa tggctgaacc cttgtctaca ttctttttaa ggagttcgag gtagaaagga
     8041 gcagatttgt tgatggagta gcgctcgtaa aattctgctg gaattttttc aatcgcagca
     8101 tcgagaattt ctggttcatc gataaacata catttaacaa tttctttgcc agccatttct
     8161 tcaggggtac ggtagaagat aggcatgctg acgagggttg attcgtgtac agtgtatttt
     8221 ccgatattgc gatttgcagt atagataccg tccttggtaa tggcatgcat gtggacaccg
     8281 agcttgcgac tgaggaattc catatccaga taatcctcat aggtcaagga ttcgctgata
     8341 atctcatggc cagtagcagt ttcttggaca agggcaccat tgaaggtcac cacatagtca
     8401 ccttggtctc tcaactgcaa gtcgtccaga agtttggcaa cacctgcgat ggggcggcca
     8461 gttgcaatca cgactttgac accagcttct ttggcatctt ggatggcaga aaagacttca
     8521 ggagtgattt ccttttggct gttgactagg gttccgtcaa tatcgacggc aattagttta
     8581 atactcataa aattcctctt ctagttttta tttggggtaa aatgatcgtt ctcaatcaag
     8641 tgtaaaaatt gctgggtaat gcttgcgaag atgctgtttt ggtctaacat ttctttaggg
     8701 aaatagaaac gattatctcc gtggcgactg ccagcaaggg attggacgat aggagacagg
     8761 ctagagagtt cggccagttc tccatttttt tgtaaaatct caatctgtgt ccgtggattt
     8821 tgagattcgg gacgatagat atcataaggg aggtcaaagt tcttatgaat ggcagtatag
     8881 tagtcgggat caaagccgat gtcctcaacc aattttctca tgctagtaag ttgatcttgg
     8941 tcctcttgtg aaaaggtaat ggatttaaag accttgcggt tgacaaagcg ttgagataaa
     9001 tctgcaagaa ttttgtcagg actagtcatc caaagctgga agtaggtatt catcacgcca
     9061 tcatccagag ccagatagtc agtcaaggtc acattttttt cgaagaaagg caggagatgt
     9121 ggggaagttc gtgcaaagaa attcttgtcc tcagggtaga gttccttggc gcgcttgaga
     9181 agattctgta ggagaacttc catggcgcgt gttgctgggt ggaaataaac ctgcatgtac
     9241 atctggtagc gactgaggac gtagtcttcg atggcgtgca tgccattgcg ctgaaaggcg
     9301 ataccatttt cgacaggacg aatgactcgg aggatgcgag tcaggtcaaa ttccccatag
     9361 gatgctcctg taaaatagga gtcgcgcaag agatagtcca tgcgatctgc gtcaatctga
     9421 ctagaaatga gctgcacgac ctgcttatta ggataggtat ggtcaatgac actggccacc
     9481 ttttctggga aatcaggtgc cacttgtagc aggacttggt gaatctctgt ctcaggattt
     9541 tgaataatct cctgagtaat ggcttcatgg tctgtatcaa agagattttc aaaagtatgg
     9601 gagtaggcac catgcccaag gtcgtgtagg agagcagcgg tcacggtcaa gagagactcg
     9661 gcaggattcc attcctcagg atatttttct tcgaaaatct ctgtgatgcg tcgtgcaatt
     9721 tcatagactc ctagacagtg agagaagcga ctgtgttctc caccgtggaa ggtataactg
     9781 gaagttccca gttgtttgat ccggcgcaaa cgctgaaatt cttttgtatt aatcaagtca
     9841 tagatgattt gattattgac atggatgtag ttgtgaactg ggtcacggaa tactttttcg
     9901 ttcatatgac cattatagca aaatcctgct ctttttggta aaatagtagg acaagagaca
     9961 agaaagaggg cctgatgtga agattcggat gcgaaataca attcagtttg atgagcagtt
    10021 ggaagtgatt gaccagcttt atgatgtgga agtgcatgaa aaaggagatt atagctacct
    10081 gcttttctat aatgaggaaa aggaaaaagt agtgattaaa tttcatggtc aagaacttat
    10141 gatgagccga ttttctaatc ccaagaccat tatgcgcttt ctaaaggata gcgatagttt
    10201 agcctatatt cctacaccta tgggcatgca ggagtttatc atccaaacga gccattatca
    10261 agttgatagg caaaagattg aactagatta tcaactacaa aatcaagagg gacatccttt
    10321 tgccagctat caattggaaa ttacttgggg ctaggctcat gtctttttca aatttagcta
    10381 tctatcttct tggatcggct tcctagtgtg gtagattagg ctaatttttg gtataataaa
    10441 agttatggaa atcgaaaaaa ccaatcgtat gaatgcgctc tttgaatttt atgcggcgct
    10501 tttgacagat aagcaaatga attatatcga gctctactac gctgatgatt acagccttgc
    10561 tgaaattgcc gaggagtttg gtgtcagtcg tcaggctgtc tatgacaata tcaagcgaac
    10621 agaaaagatt ctggaagatt atgagatgaa attgcacatg tactcggact atattgtccg
    10681 cagtcagatt tttgatcaga ttttggagcg ctatcccaag gatgactttc tgcaggagca
    10741 gatagaaatt ttaacaagca ttgataatag agaataagag gaagaaaaat ggcatttgaa
    10801 agtttaacag aacgtttgca gaacgtcttt aaaaatctac gtaaaaaagg aaaaatctct
    10861 gaatctgatg tccaagaggc aaccaaagaa attcgcttgg ccttgctcga ggccgacgtt
    10921 gccttgcctg ttgtaaagga ctttatcaag aaagttcgtg agcgtgcagt cgggcatgag
    10981 gtcattgata cacttaatcc tgcgcaacag attattaaaa tcgttgatga ggaactgaca
    11041 gccgttttag gttctgatac ggcagaaatt atcaagtcac ctaagattcc aaccatcatc
    11101 atgatggttg gtttacaagg ggctggtaaa acaacctttg ctggtaaatt ggccaacaaa
    11161 ctcaagaaag aagaaaatgc tcgtcctttg atgattgcgg cggatattta tcgtccagct
    11221 gccattgacc agcttaagac cttgggacaa cagattgatg tgcctgtctt tgcacttgga
    11281 acagaagtac cagctgttga gattgtacgt caaggtttgg agcaagccca aactaatcat
    11341 aacgactatg tcttgattga tactgcgggt cgtttgcaga ttgatgagct cctcatgaat
    11401 gagcttcgtg atgtgaaagc attggctcaa ccaaatgaaa tcttgcttgt cgttgatgct
    11461 atgattggtc aggaagcagc caatgttgcg cgtgagttta atgctcagtt ggaagtgact
    11521 ggggtcatcc ttaccaagat tgatggcgat actcgtggtg gtgctgctct gtctgttcgt
    11581 cacattactg gaaaaccaat caagttcact ggtacaggtg aaaagattac ggacattgaa
    11641 accttccacc cagaccgcat gtctagccgt atccttggta tgggggatat gctcactttg
    11701 attgagaaag cttctcagga atacgatgaa caaaaagccc ttgaaatggc tgagaagatg
    11761 cgcgaaaaca cctttgattt taatgatttc atcgatcaat tagatcaggt gcaaaatatg
    11821 gggccgatgg aagacttgct caagatgatt ccaggtatgg ccaacaatcc agcccttcaa
    11881 aacatgaagg tggatgaacg ccagattgct cgtaaacgtg ccattgtgtc ttcgatgaca
    11941 cctgaagagc gtgaaaaccc agatttgtta aatccaagcc gtcgccgtcg tattgctgct
    12001 ggttctggaa atacattcgt cgaagtcaat aaattcatca aggactttaa ccaggctaaa
    12061 cagctcatgc agggtgttat gtctggggat atgaataaaa tgatgaagca aatggggatt
    12121 aatccaaata accttcctaa aaatatgcca aatatgggag gaatggatat gtctgccctt
    12181 gaaggaatga tgggacaagg cggtatgcct gacttatcag ctctcggagg agcaggaatg
    12241 ccagatatga gccagatgtt tggtggcggt ttgaaaggta aaattggtga atttgccatg
    12301 aaacagtcca tgaaacgtat ggctaacaaa atgaagaaag cgaagaagaa acgcaagtaa
    12361 gacaagagat tgatgcaaat ctcatttgat gagaaaataa agtaaaaatt tctatgataa
    12421 aacgtacagt atcaaggttt tagaatatct gatattatac gttttttgat tttaataatt
    12481 ttgttaagac acttttatta tggtatacga aaaatccact cagctgtctg agtggattag
    12541 gtgtatttag actcttagtc tttattttcg tatggcaaga tcaagttcaa gatgattcct
    12601 gtcatggctg aaagggcagt acctgaaagt gtaactggac caagtttaag gatagctcct
    12661 ccaagtccaa gaaccaacat agcacttgcg atgatgaggt ttcgcatttg agcgaaatca
    12721 acacgttctt taatcaagac tttcaaacca ttgctggcga taaccccata gagaaggatt
    12781 gacataccac caagtacagc gtttggaata gttgaaatca aggcagtgaa tttaccaagg
    12841 aagctgaggg caatcgcgat gaaggcagcg ttacggataa ctgagacaga agcgatacga
    12901 gtcataccga taacccctgt attttctccg taagttgtat tggctggtcc accaaggaag
    12961 gcagaaacag aagttgcgat accgtcacca agaagagtac ggtgaagacc tggttctttt
    13021 aagaattgac gaccacagat ttgacccaaa acagtatggt ctccgatatg ttcagaaatt
    13081 gttacgatag cgattggcaa gatagcgatg gcttctggac caaagtaaag attgtactct
    13141 ttaaaggcac cacctgtgct aaatggcaag tagaaaccag gaatttcgaa ccagttggct
    13201 ttaagaactg gtgtaaagtc aaccaagcca agagttagtg cgaaaaggta accaccgata
    13261 atggcaaaga ggaatggaat gattcgtagg aagccttttc cttttgtatt gataaaggca
    13321 gcaattagga aagtaacaac ggctaccaga gcatttttcc aatttccgtc tgctacaaga
    13381 cctgcattgg taacagctga acctgcaagt ccaagaccga taacgatgat cataggaccg
    13441 ataatgattg gtggcaagag tttatcaatc cattttgttc ctacaaatcg gatgctggta
    13501 gcaacaagga catagaccaa accagtcaag ataacccctg tttgggcagc agatacatcc
    13561 ccccccattt ctttcatagc cagtgacata gctgtgataa aggcaaatga agaacctaga
    13621 taaactggaa ctttaaaacc agtagcaatc atgtagatga gtgttccaac acctgaagca
    13681 aaaagggcaa cagatacagg cattcccaaa atcaatggta ccaagatggt cgcaccaaac
    13741 atggcgaaaa cgtgttggaa actaaggaga attccttttc cagccgaagg acgttggtca
    13801 acgtctagta acaaatcaac agttgattct tgtttcatat aaacctcact tttgggcatc
    13861 aaaaaagagc ccattatttt acagcaatag gccctcagag taagacttct ttaaaattta
    13921 gattttaaag agttttaaat atttctgcgt cttcgtcacc tcacgggatg acattaaaaa
    13981 cctttgctta ggatagtata gcagaaaaaa atgattttgt aaatcatttt ttcccgagcc
    14041 tagaaataaa agagcgaggc tgattttgta aatcattttt tcccgagcct agaaataaaa
    14101 gagcgaggct gattttgtaa acatttgttt actaaaaaat ttaaagtggg cgtttatttg
    14161 gcataccagc cttacgcgga tatttatttg gtgtttcttt tttcttttct accactgtga
    14221 tatagcgcgg atctctattc ggtagggcgt agctgagatt gtcttcgacc ttactaaaaa
    14281 ggagattgag ggcattctta gcttctaata attcctcagg cgcattgctg gccttgagtg
    14341 ccaatagttt tccaccaacc ttaaggtagg gaatggtcaa ttcagatagg acctgcatac
    14401 gggcaaccgc acgagctgtt acaaaatcat attgagcacg gaagttcttg tcttgggcaa
    14461 aatcttcggc acgtccgtgg tagaaatgaa ctccgttcaa atccagttct tgagccaaga
    14521 gttgtaggaa gttgatgcgc ttattgagtg aatcaataat ggtcacatct aactccggat
    14581 agagaatttt cattggtaga ctaggaaatc ctgccccagc cccgatatca agaagtttga
    14641 tagtttcatt gggaatcaaa ccttgaagaa tgggtgcaat cgaatcgtaa aaatgtttga
    14701 gataaacttc ttccttgtcc gtaatcgccg tcaaattaat cttctcattc cactcgacca
    14761 agagctcaaa ataacgttca aattgttctt tttgctggtc cgaaagtgga agattctgct
    14821 cggcaagcaa gttgtaaaat gtttttggtt tcatagttat ttccttcttt agtatcatct
    14881 tattttacca caatcataga aaatttgata tactggtact aatctaaaag cagaaaggac
    14941 ttatattatg acttggatta ttcttggagt tatcgctctt attgttattt ttgtgattgt
    15001 tagctataac ggtttggtta aaaatcgtat gcaaaccaag gaggcttgga gtcagattga
    15061 tgttcagttg aaacgtcgaa atgacctctt gccaaacttg attgagactg taaaaggtta
    15121 tgccaaatat gaaggttcta cccttgaaaa ggtggcagaa ctacgtaacc aagtggcggc
    15181 agcgacttca ccagcagaag ctatgaaagc cagtgatgcc ctcactcgtc aggtttcagg
    15241 tatttttgca gttgcagaaa gctatccaga tttgaaagct agtgctaact ttgttaaatt
    15301 gcaagaggag ttgacaaaca cagaaaataa aatttcttac tctcgtcaac tctataacag
    15361 tgttgtcagc aactacaatg taaaattaga aactttcccg agcaatatta tcgctggaat
    15421 gtttggattt aaagcggcag atttccttca aacatctgaa gaggaaaagt cggttcctaa
    15481 agttgatttt agcggtttag gtgactaaga tgttgtttga tcaaattgca agcaataaac
    15541 gaaaaacctg gattttgttg ctggtatttt tcctactctt agctcttgtt ggttatgcgg
    15601 ttggttatct ctttataaga tctggacttg gtggtttggt tatcgcactg attatcggct
    15661 ttatctacgc tttgtctatg atttttcaat cgacagagat tgtcatgtcc atgaatggag
    15721 cgcgtgaggt ggatgagcaa acggcaccag acctctacca tgtagtggaa gatatggctc
    15781 tggtcgctca gattcctatg ccccgtgttt tcatcattga tgatccagcc ttaaatgcct
    15841 ttgcgacagg ttctaatcct caaaatgcgg ctgttgctgc gacttcaggt ctactagcta
    15901 tcatgaatcg tgaagaacta gaagctgtta tgggacatga agtcagtcat attcgtaatt
    15961 atgatatccg tatttcgact attgcagttg cccttgctag tgctatcacc atgctttcta
    16021 gtatggcagg tcgtatgatg tggtggggtg gagcaggtcg cagacgaagt gatgatgacc
    16081 gagatggaaa tggtcttgaa atcattatgc tagtggtttc cctactagct attgtactgg
    16141 cacctctcgc tgcaaccttg gttcagctcg ctatttctcg tcagagggaa tttctggcag
    16201 atgcatctag tgtcgagctg actcgcaatc cccagggaat gattaatgcc ctagataagt
    16261 tggacaatag caaacctatg agtcgccacg tcgatgatgc tagcagtgcc ctttatatca
    16321 atgatcctaa gaaaggtggg gggttccaaa aactctttta tacccaccca cctatctcag
    16381 aacggattga acgtttaaaa cagatgtaaa agaatccaga ggtcgtctct ggatttttgc
    16441 tatgttgcaa atttataaat cttctaaatt aactagcttc aaaccgtgtt ctgtcatgcg
    16501 atagatgatc gagcagactt cttttaagaa acgacggtca tgcgaaacag tgatgagacc
    16561 gcctggatag gttgcaaaga gttttctgat ttggggttga gaagtgggag aaaagtttcg
    16621 tgtgggttca tccagcagga gaaagtttgg tttgcgcaga actagatcca aaagcaggag
    16681 ttttccctgt tgtccgccag ataaggagcg aatttgatgc tgcatttctg gataactgaa
    16741 attgagactg gctaggtgag attggatttt ctgaagttcc tctttttccc cagttttgct
    16801 gatataagct attgaggata aatccaattg cagttttttg tggtaatctt gtggcataaa
    16861 accaagtgaa atctctcttt tatcattcag aagttgctgt aatttggcta acagagttga
    16921 tttcccaaca ccatttgggc cgatgatacc gattttttct tggccacgga cagttagttg
    16981 cagttcctga gccaaaacac ggtcgtcaat ggacaaattt tctttttcca gttggactaa
    17041 gactttagaa gctggtaatg gttggatgtc tgaaaagaaa agttggattt gttcctcttc
    17101 aagtggcttt tgagtcatgg actgagctgt cttttcgtag cgtttttctt gtgagaggac
    17161 agttttcatc tttttagcca ataggcgacc ggcagtacta tctttggtag ctcgaagcgc
    17221 agtttctaca ttttgcttaa ctctccgatg tttttccatg gttttatcgt aggctctttg
    17281 gttgttagca gcttgctgac tttgtttggc aaaattagcc tttctctgct cactatagct
    17341 atcatagtct aaatgctcta ctagcgtttc cgcttcttta cggtgtttga ccagtcgcaa
    17401 gtgaacaata gtgtctgccg tttcagaaag aaagtcttca tcatgggaaa tgaaaataac
    17461 ggtttgcctg gtcttttgaa tctggccttt tagccaatca actgtctcaa ggtctaggtc
    17521 atttgaaggt tcatctaaaa atagaatctc aaagggtttg gctaactcat ggataagctg
    17581 aattttcaaa gcttcgcccc ctgatagatt gccaatctct tggtcacttg cgaaacgatt
    17641 gctatcaaaa tgcaattcct ccgccaaacg atagaggata ctgtagtcta aatcaataga
    17701 atctaaaaag aagtagtcgt gtaaagtttt cttttttagg tcctcaggga ctttttgagg
    17761 aatgtaggcc agtgactgat aatcagactg gatgtctccc ttgatagtga aatcagacaa
    17821 atcttccccc attaaagttt taagtaaggt tgatttacca tttccttctt cgccaataat
    17881 agctaccttt tccccgtctt gtatggtcat gcttaggtca gagacaaggt ctcgtaaatc
    17941 tttgttttgt gtgatggtca ggtgattgat ttttatcata ctattgccct ttctagaatg
    18001 tcgatagtgc ataacaaaaa gctctacttt acctagtaga gcccaaagtc tatgtcaaaa
    18061 aaactctatt aacatgccag aaaaagagca taaaagagca cacaaaaaga gacaaaaaca
    18121 agatctacta aataaaggtt ctttatttga tagacttagt tgttcatgtc tcccttacct
    18181 ccgagtatta gtatctttat actatacttt taaggaaatt ttgtcaacag aaaactggaa
    18241 attctatgct ctaaaatcca aaaacaggtc catagagact tagtacgtgt ttgacatgct
    18301 cgtaatggat tttatcatag tttcgccaag cagtgcgtgc ttgatcgttt agttttaggc
    18361 tacccagtcc aatcagagga ctggtgggtt ggtaaaattt ctcaagatca attaagatac
    18421 tgttgttcaa cttttccgtt tttttgagct cttgcatagt agtgtttagc agctcttgta
    18481 gtcgaatatc atctgccgta ccctgtttac agttttggta gcttttattt aacttggata
    18541 ggagttgaat gagtttcttg tcttccatgt cttccatatg agcatcctcc ttgatctgat
    18601 gtactctttc cctatagtat agcactaaaa aataaaactg tcatagtaaa tatgttaaaa
    18661 ttttgaattt taattacaaa gtttggtgtg ctgatttgta gccttttcat ggtataatca
    18721 agagagtaaa tctttatgga ggaagtatga aattaaatat tcaagaaatt cgtaagcagt
    18781 ctgaaggttt gaactttgaa caaacgttag atttagttga tgacctgcgt gcacgtaatc
    18841 aagaaatttt agatgtaaaa gatatccttg cagttgggaa agtacaatat gaagaccgta
    18901 tgtatttctt agattatcaa ctatcttata ccattgttct tgcttcgagt cgcagtatgg
    18961 agccagttga gttagttgaa tcttatccag tcacggaagt tttcatggaa ggcgcaacta
    19021 accagctaga tcaagaagtt ttagatgatg acttggtctt gcccattgaa aatggggagc
    19081 ttgaccttgc tgagagtgta tcagacaata tcctgctaaa cattcctatc aaggtcttga
    19141 cggctgaaga agaagctggt caaggattta tctcaggaaa tgactggcaa atcatgacag
    19201 aggaagaata ccaagctcaa caagcagtaa agaaagaaga aaacagtcct tttgctggct
    19261 tacaaggact atttgacgga gatgaataat ggtcttgtca aaaaaacgag cacgaaaggt
    19321 gctagaagaa atcattgccc tcttcccaga tgccaagcct agtcttgatt ttaccaatca
    19381 ttttgaactc ctggttgcgg tcatgttatc agcccagacg acagatgcag cggtaaataa
    19441 ggccacacca ggtctctttg ttgcctttcc aacaccccaa gctatgtctg tagcgacaga
    19501 gagtgagatt gcttcacata tttctcgctt gggattgtat cggaataaag ctaaattcct
    19561 taaaaaatgt gcccaacagt tactagacga ttttgatggt caagtccctc agacacgtga
    19621 agaattggag agtttggcag gtgttggtcg caagacagcc aatgttgtca tgagtgtagg
    19681 atttgggatt ccagcctttg cagtggatac tcatgtggag cgtatttgca aacaccacga
    19741 tattgtcaaa aaatcagcga cgccacttga ggtggaaaag cgggtcatgg atatcttgcc
    19801 gcctgagcag tggttagctg cccatcaggc catgatttat tttggaagag ccatttgcca
    19861 tccaaaaaat ccagagtgtg accagtaccc acaattatat gattttagca atttgtaaga
    19921 tgctacattg aaactttttg cttgatttta agcatgcttt gtgctatagt aaatgataac
    19981 taaatattcc tttaaacctg tcccgtgagg caggcaagga gcgcgataaa gtagaagggt
    20041 gaagtctata ctgtttgcag tagggctcgc ttggctataa atttcaagtc tccttgttta
    20101 aggagacttt tctttttgga ggtttgtcat gaaaacaaaa gaagttgtag acgaattgac
    20161 cgtcaaacga gcgattacgc gtattactta tgagattatc gaacgcaaca aagatttgaa
    20221 taagatcgtc ttggctggta ttaaaactcg tggtgtcttt attgcccacc gaatccaaga
    20281 acgtttgaag cagttagaaa atctttcagt tcctgttgtg gaattggata ctaaaccttt
    20341 ccgtgatgat gttaaaagtg gagaagatac ttctttggtt tctgtcgatg tgacagaccg
    20401 cgaagttatc ttggtggatg atgtgctcta tacaggtcgt accatccgtg ctgctattga
    20461 taatattgtc ggtcatggtc gtcctgcgcg tgtgagttta gcagttctag tcgatcgtgg
    20521 acatagagaa ttgccaatcc gtccagatta cgttggaaaa aatatcccaa ccagtcgttc
    20581 tgaagaaatc atcgtagaga tgacagaact tgatgaccaa gacagagttc tgattactga
    20641 agaagcttag aaagttaaag gagtagccat gtcagaaaat caacaagcat tgaaccatgt
    20701 ggtgtccatg gaagacctca ctgtcgatca agtaatgaaa ttgatcaagc gaggaattga
    20761 gtttaaaaat ggagcccagc ttccctatga agaccatccg attgtttcca atctcttctt
    20821 tgaggattct acacggacac ataagtcctt tgaagtcgca gagattaaac ttggattgga
    20881 acgacttgac tttgatgtga agactagttc ggttaataag ggtgagacac tttatgacac
    20941 cattttgact ctgtctgctt taggagtgga tgtctgtgtg attcgccatc cagaggtcga
    21001 ctactataga gaattgattg ctagtccaac gattacgact tccatcatca atggtggaga
    21061 tggttcgggc caacacccta gccagagctt gcttgatttg atgaccattt atgaggaatt
    21121 tggccacttt gagggtctta aagttgctat tgcaggtgac ttggaccact cacgcgttgc
    21181 caaatccaat atgcagattt tgaaacgctt gggagctgaa ctctttttcg ctggacctga
    21241 ggaatggaga agtcaagagt ttgcagacta tggaaagttt gtaaccattg atgaaatcat
    21301 tgatcaggtt gatgtcatga tgtttctccg tgtgcaacac gaacgccatg atagtggagc
    21361 tgtattttca aaagaagact atcatgccca acatggcttg actcaagaac gttacgatcg
    21421 tttgaaagaa acagcaatcc tcatgcaccc agctccaatc aatcgtgatg tagaaatagc
    21481 agaccacttg gttgaagcac caaaatcacg gattgtccaa caaatgacca atggtgtctt
    21541 tgttcgaatg gcaatcttag aatccgtact agcgagtaga aacgccaact aaaacacaag
    21601 acgttaaaag acgccagtga gcgtccacga gaggtgaaaa tatgacaaaa agaattctag
    21661 tattagaaga tggcacagtt tttgaaggca aggccttcgg agcagatatt gatgtaacag
    21721 gcgaaatcgt ctttaataca gggatgaccg gctaccaaga atccattaca gaccagtctt
    21781 ataatggaca aatcttgacc tttacttatc ctttggtagg aaattatggt attaatcgtg
    21841 atgattatga atccattatt ccaacttgta agggagtcgt tgtttttgaa gaagcgcgta
    21901 gagctagcaa ctggcgcaac caaatgacct tggatgaatt tttgaaagcc aagaaaattc
    21961 cagggatttc aggaattgat acgcgtgctc ttaccaagat tatccgtaag catggtacta
    22021 tgcgtgcaac cttgacccat gttggggaca gtatggacca tgtgacggac cagctccaag
    22081 caacagtttt accgacagac aatatcaaac aggtttctac taaaacgtct tatccagctc
    22141 caggagttgg tttgagcgtg gtgctagtgg actttggtct caagcactca atcctacgtg
    22201 aactttctaa acgcaactgt aacgtgacag ttgttcctta ttcgacaacg gctgaagaaa
    22261 ttctccatct caatcctgat ggagttatgt tgtcaaatgg tccaggtaac ccagaagacg
    22321 ttccacaagc actcgacatg attcgcggtg tacaaggaaa aattccaatc tttggtattt
    22381 gtatgggaca ccaactcttt gcaatggcaa acggggctaa gacctataag atgaagtttg
    22441 gccaccgtgg attcaaccat gcggtacgtg aaatcgcaac aggacgagta gacttcacca
    22501 gccagaacca tggttatgca gtcagccgcg aggatttgcc agagcacttg attattaccc
    22561 acgaagaaat caatgacaag tcagtggaag gtgtgcgcca cagataccaa cctgctttct
    22621 ctgttcaata ccacccagat gcagctcctg ggccacacga cgctagctac ctatttgacg
    22681 agtttatcga gatgatggaa gtttttaaac aatcaaacta agaatgagta aaagctcgtc
    22741 ggagaattta tgtaactgaa catggacgga aagctcagaa tttagagaaa ccaacttgga
    22801 ttgtcaatcc ttccttgatt tcctaaaatt caatcgcttt ctagtcgtcc tttgtatctt
    22861 atttaatgtc gccctgagag gcgacgaata gaaaggagaa gatacattgt tcgcggaagt
    22921 gaacacgccc taagaactgt gtgaaaaaga taaacatcgt cttgacgctg aaggcgtctg
    22981 cgccgagttt cctattttca ctgtgttctt tacgggcttt gtatcataaa ctatgcctaa
    23041 acgtactgat attcaaaaaa ttatggtgat tggttctggt ccgattatta ttggtcaggc
    23101 tgctgagttt gactacgctg ggactcaggc ttgcttgtcg ttgaaagagg aaggttatga
    23161 ggttgttttg gttaactcaa atcctgcaac catcatgacg gacaaggaaa ttgctgacaa
    23221 ggtttacatt gaaccgatta cacttgagtt tgtgacacgt attcttcgta aggaacgtcc
    23281 agatgccttg ctaccaacac tcggtggtca gacaggtctc aacatggcca tggaattgtc
    23341 taaaaatggt atcttagatg agcttggcgt tgaacttctg ggtaccaaat tatctgccat
    23401 tgaccaagcg gaggaccgtg acctctttaa acaattgatg gaagagcttg aacaacccat
    23461 tccagaatct gaaattgtta acacagtaga agaagcagtt gcctttgcag cgacaattgg
    23521 ctacccagtc atcgttcgtc cagcctttac cctcggtggt actggtggtg gtatgtgtgc
    23581 caacgagaaa gaattgcgtg aaatcactga aaatggtttg aaattgtcac ctgttaccca
    23641 atgtttgatt gagcgttcga ttgccggttt caaggaaatt gaatacgaag tgatgcgtga
    23701 ctcagctgac aatgccttgg ttgtttgtaa catggaaaac tttgacccag ttgggattca
    23761 cacgggggat tccattgtat ttgcccctgc gcaaaccatg tcagactatg aaaaccaaat
    23821 gcttcgtgat gcgagcttga gcattattcg tgccctcaag attgaaggtg gatgtaatgt
    23881 tcagctagct cttgatccta acagcttcaa gtattatgtt atcgaagtaa accctcgtgt
    23941 atcacgttcg tcagcccttg cttctaaagc gacaggatat ccgattgcta agttggctgc
    24001 caagattgca gtaggtttga ccttggatga ggttataaac ccagttacag gttcaaccta
    24061 tgccatgttt gaaccagccc ttgactacgt agttgctaag attccacgtt tcccatttga
    24121 caagtttgaa aagggtgaac gccgtctcgg tacacaaatg aaggcgactg gagaagtcat
    24181 ggcaatcggt cgtaacatcg aggaatctct tctcaaggcc tgccgctccc ttgaaattgg
    24241 ggtgcaccac aatgaaatac ctgaacttgc agcagtttct gatgatgcct tgattgaaaa
    24301 ggttgtcaaa gcccaagatg accgtctctt ctacgtatca gaagcaattc gtcgtggcta
    24361 cacacctgaa gaaattgcag agcttacaaa aattgatatc ttctatcttg ataaactctt
    24421 gcatatcttt gaaattgagc aagaattggg tgctcatcca caagatctag aagttttgaa
    24481 aacagccaaa cttaatggtt tttcagaccg taagattgct gaactctggg gaacgactga
    24541 tgatcaagtt cgccaacttc gcttggaaaa caagattgtt ccagtttata agatggtaga
    24601 cacttgtgcg gcagagttcg actccgaaac gccatatttc tattcaacct atggttggga
    24661 aaatgaatct atcagatctg ataaagaatc tgtacttgtc ctaggttcag gtccaatccg
    24721 tattggtcaa ggggttgagt ttgactacgc aaccgttcac tctgttaagg ctatccaggc
    24781 agctggttat gaagctatca tcatgaactc aaacccagag accgtttcaa cagacttctc
    24841 tgtatcagat aagctttact ttgagccatt gacattcgaa gatgttatga acgtcattga
    24901 cttggaacaa ccaaagggag ttatcgttca gttcggtggt caaacagcca tcaaccttgc
    24961 ggagccattg gcaaaagcag gtgtgaccat ccttggtaca caggttgctg acctagatcg
    25021 tgccgaagac cgtgacctct tcgagcaagc tctcaaagaa ttggatattc cacagccacc
    25081 aggacaaaca gctaccaatg aagaagaagc agctcttgca gctcgcaaga ttggcttccc
    25141 agttcttgtc cgcccatctt atgtacttgg tggacgtgcc atggaaatcg ttgaaaacga
    25201 agaagacctt cgttcttaca tgcgaactgc tgttaaggct agtccagacc acccagttct
    25261 tgtcgactct tatatcgttg ggcaagagtg cgaagttgat gccatttcag atggtaaaaa
    25321 tgtactcatt cctggtatca tggagcatat cgaacgtgct ggtgtccact caggtgactc
    25381 aatggctgtt tacccaccac aaaccttgtc gcaaaaggtt caggagacca tcgcagacta
    25441 caccaaacgc ttagcaatcg gtcttcactg ccttggaatg atgaacatcc agtttgttat
    25501 caaggatgaa aaagtctacg ttattgaggt caatccacgt gccagccgta ctgttccatt
    25561 cctatctaag gtaaccaata ttcctatggc tcaagtagcg accaaactca ttcttggtca
    25621 aagtttatca gaacttggct accaaaatgg actttaccct gaaagcaccc gtgttcatat
    25681 caaggcacct gtcttctcct ttaccaaact agctaaggta gacagcttgc tcggtcctga
    25741 aatgaagtca acaggtgaag ttatgggttc tgatgctact ttggaaaaag ctctctataa
    25801 agcctttgaa gcttcttatc tacacttgcc aacttttggt aatgtcgtct ttaccatcgc
    25861 tgatgatgcc aaagaagaag ccttgaactt ggctcgtcgt ttccaaaaca ttggttatgg
    25921 aatccttgcg acagaaggga cagcagcctt ctttgctagc catggcttgc aagcccaacc
    25981 tgttggtaag attggtgatg acgataagga tatcccaagt tttgtacgca aaggaagaat
    26041 tcaagctatc attaacacag taggaacaaa acgaactgct gacgaagatg gtgagcaaat
    26101 tcgtcgttca gccattgaac acggggtgcc cctcttcaca gcgctagata cagctaatgc
    26161 catgcttaag gtacttgaaa gtcgtagctt tgttacagaa gcgatttaaa tagaaaaata
    26221 agatatagca gactgaattt agaacagtac acaggaatac taaaatattt ctagaaatta
    26281 atttgaattt tctaattgat ttgttcgcat cttatttcaa tctactatag aaaaaagtct
    26341 ttaaaattat aaaacgcatc atatcaaggt ttttcaaaaa ccttgatatg atgcgtttta
    26401 ttgtgggaat atgtatttca ttttctacta aaattatgtt tttgaataac ctctatctta
    26461 gtagtttgta taatccccct caatcagttt ttgcgataag ctttaatgct atgactatac
    26521 cactcttgca tttcttttga tggtggtgtc atataatcgc catacatctg ggttaaaaat
    26581 tggtcatatt ttttgggaac aggcaacata cggccctcaa actcagttaa aatcagttct
    26641 ttaaaggtat caactgggaa gatttctttc atcccttcct taccgatccc aactcctcct
    26701 tcatattgag gaatgttggt tacagcattt ttgactagtt gatcaatttt cttgtaaaag
    26761 tagcgaggat tgacaaatcg gagagcgtac cagctacata atctaagaaa atcttttagt
    26821 ttgctatcac cgtgaactgc tcgtgatttt ttgatgtaag ctagttgacg aagggccaca
    26881 tacttatagc tcttgtcgac aatgctcaag tctgtaaatt gatcaattgg gaagacatcg
    26941 atgaaaaggc tggtatcatg acgcttgtac ttaacatggt cttctataac agtagaagta
    27001 tccaaaatcg atgcgaaatt atggaagtac caagaagatg tatcgtagga aagaaccttg
    27061 tagcgagggt gattttcttc ttcaataatc ttcagtaaac gctcataatc ctcacgataa
    27121 agggaaatat caatatcatc atcccaagga atcatacctt tgtggcggat ggctccaagc
    27181 atggttccat aactgagaaa ataaggaata tcatgtttct tacaagtctc atcaatatag
    27241 tccagcaggg ctagttgaat ttctttaatt tctttttttt ctaaatattg catcctaatc
    27301 ctccaattta taagcgtgaa attcatgact gtagaagcgt ttttcttctg gtggtagggt
    27361 catataatct ccataaaatt gtgtcaaaat agtatcaaat ttttcaggtg caggaaggct
    27421 taaattctca aagggtaaat cgattgtttt atcaaaggta gcacttggga agacttcctt
    27481 ttccttaaat tttgaaggaa taaaagccat atactgccca ttttcacgac tatatttttg
    27541 aatttctttc tcgattttat ttgcaaaata acgaggagaa accagtcgaa ggagcaacca
    27601 aaaggctgtt cgtatccaat cttttaaaag gctatcctta tagacaatat ttttatgttt
    27661 actgaaagac agcagtttga agctttctag tttataacaa gtatcaatga ccttaggatc
    27721 atcaaagcga tccataggga aaatatcgat aaagatacca gactcatagg tttttgtatt
    27781 tcgagtatca ataattttag tcgtactgtc ggttatcttg ataaagttgt taaagtagtt
    27841 cttatcagtt tctaaggata ggagcttata cttgcttttt tccttttgaa aaatgttaat
    27901 aaatcgttgg tagtcttctc taggcatgga taaatcaata tcgtcgtccc aagggataaa
    27961 gccctcatgt cgaaccgccc caatcagagt accgtagtta ataatatagt tgatattgtg
    28021 ctttttacag agagtatcaa tataattcaa aatttctaat tcaatttgtt tggcatcttc
    28081 aacggttagt tgtttcattt taaactccta agatttttta aatttatttt ttaaggctag
    28141 gacatggttt aaaaattcat agaaaatgct atcttttgtg aagacaagta gactaatata
    28201 agagatagct gatagcaaga caatcaaacc agtattaatc aaaaatggca aattaatgac
    28261 catatccaca ggatacacga aattaatcag gaaataaatt gctacaaagg aaagtgaaaa
    28321 gagagagtat cgaacagtat agctaaagat atgtcccaag tggatgagtt gttttctatg
    28381 gatgaaaatg atatagaaaa caagtagaga agcctctgat aacatagttg tcagtaagta
    28441 gtattcggga gccacgatat ggttgaaaaa gaggagacta ttcaagccca aattgagtag
    28501 cccagcaaag actgtataga ctgtgatacg tttttcatag ccattggtaa agagaatttg
    28561 ggaaccaaga atggtatcta aggccaggat aatcgtacga aaagcgaaga gagaggtcaa
    28621 gatgtcgcct ccgatatatt tttcactacc gtaaagtagg atggcatttg gtcctaaaac
    28681 catgagtcca aaactcagtg gaatgataaa gaagttaaag attcgactac ctctattaac
    28741 cagagaaaca taggcttctt tgtctccttt ccccagatag taactgagac gaggcacact
    28801 cactccaatt gcacctgtta caaccccagc tataacggtc acaattcgct gagctatggt
    28861 atagtaacta acgttgacat caatccctgt tttaacgagg aagaggcgat ctaaaaaagt
    28921 gaagagcata ttggcattgg caaagactaa catggctgtc agagggagaa agagtggttt
    28981 aaaatcactt aggtgaatct taacaagttt gatgtctctt ttaatccaaa aataactaat
    29041 caggtagtta atcagcgtcg ataaactcat cacaagtgta tagacaacaa tatcgtgttc
    29101 atttttaaca aataagaaaa tagagaccag catcaggata cggatgaagg cagttttgta
    29161 aaagagaaaa ctgtaatttt ccagagcttc attgacccat tcgattgaaa aaatctgggc
    29221 aatgagttga atccccataa caaggtagac ctttttgacg attggattat cagtaaagaa
    29281 gagaggatag gctaggatat agacagcagt ggtcaaaatc gtacaagcga tgcacaaata
    29341 aaaaagacta gaaaaggttc tgttaagatc ttttttgtta tccttgacat tactgatagc
    29401 ccttaaaccg tagttataga caccataagt tgcaaagggc aagaaaaatg acaaaatagt
    29461 gtcgactgag ttgaagtaac catagtcagt tcggtccaag acacgcgcga cataggttcc
    29521 agttaggatg ggaaaaataa tattcaagac acgaattccc atgtaagata gagcatttaa
    29581 ttttatactt ttcattcaat ttacctcgtt tttcattata tcataaagtt agctaataag
    29641 aaatgaaggg cagtaagtca agtaatcact ttgaagtttc aaatcttaag ttttaagttt
    29701 tctttaagga aagtatatta ttctgaagga ctctaaaatt tcgcagccat ttattagtaa
    29761 ttgctacaga attcctagtc attactagaa atggactagt ttctttgaat aatagaactg
    29821 cataattctc ctattctaga aggggaggac cagtatttct tttatgatag gactagattg
    29881 tggtataata gagagaataa gtttttttag taagacaaag gagaaaatag atgatttatg
    29941 caggaattct tgccggtgga actggcacac gcatggggat cagtaacttg ccaaaacaat
    30001 ttttagagct aggtgatcga cctattttga ttcatacaat tgaaaaattt gtcttggagc
    30061 caagtattga aaaaattgta gttggtgttc atggagactg ggtttctcat gcagaagatc
    30121 ttgtagataa atatcttcct ctttataagg aacgtatcat cattacaaag ggtggtgctg
    30181 accgcaatac aagtattaag aaaatcattg aagccattga tgcttatcgt ccgcttactc
    30241 cagaggatat cgttgttacc cacgattctg ttcgtccatt tattacactt cgcatgattc
    30301 aggacagtat ccaacttgcc caaaatcatg acgcagtgga cacagtggta gaagcggttg
    30361 atactatcgt tgaaagtacc aatggtcaat ttattacaga tattccaaat cgtgctcacc
    30421 tttatcaagg acaaacacct caaacattcc gttgcaagga cttcatggac ctttatggat
    30481 ctctttctga tgaagagaag gaaatcttga cagatgcatg taaaatcttt gtgatcaaag
    30541 gaaaagatgt ggccttggcc aaaggtgaat actcaaatct gaagattaca accgtaacag
    30601 atttgaagat tgcaaaaagt atgattgaga aagactagta aaatgattaa tcaaatttat
    30661 caactaacta agcctaagtt tatcaatgtc aaatatcagg aagaggctat tgaccaagag
    30721 aatcatatcc ttatccgtcc caactacatg gctgtctgtc atgcggatca gcgttactat
    30781 cagggaaaac gtgatcccaa gattttgaat aaaaagcttc caatggcaat gattcacgag
    30841 tcatgtggaa ccgtcatttc tgacccgacc ggaacctacg aggttggtca aaaagttgtc
    30901 atgattccca atcagtctcc tatgcagagt gatgaagaat tctatgaaaa ctacatgaca
    30961 gggacccatt tcttgtctag tggatttgat ggctttatga gagagtttgt ttctctccct
    31021 aaagatcgtg tggtggctta tgatgctatt gaagatacgg ttgcagccat tacagagttt
    31081 gtcagtgtgg gcatgcacgc tatgaatcgt ctattgactc ttgctcatag caagcgggag
    31141 cggatcgccg ttattggaga tggaagttta gcttttgtgg ttgccaatat tatcaactat
    31201 actttgccag aagcagagat tgtggttatt ggtcgtcatt gggaaaagtt ggaactcttc
    31261 tcatttgcca aagaatgcta tattacggat aatattcctg aagagttggc ctttgaccat
    31321 gcttttgaat gttgtggtgg tgatggtact ggaccagcta ttaatgactt gattcgctac
    31381 attcgtcctc agggaacgat tctcatgatg ggagttagcg aatataaagt caatctcaat
    31441 actcgcgatg ccttagaaaa gggcttgatt ttggttgggt catctcgttc tggtcgcatt
    31501 gattttaaaa atgctatcca aatgatggaa gtcaagaaat ttgccaatcg tcttaaaaat
    31561 atcctttatc tagaagaacc tgtaagagaa attaaagata ttcatcgtgt ctttgcaacc
    31621 gatttaaaca cagcctttaa aacagtgttt aagtgggaag tataagtact ggaggttaat
    31681 tgtggagaaa atcattaaag aaaaaatttc ttccttactt agtcaagaag aggaagtcct
    31741 cagtgttgaa caactgggtg gaatgaccaa tcaaaactat ttggccaaaa caacaaataa
    31801 gcaatacatt gttaaattct ttggtaaagg gacagaaaag cttatcaatc gacaagatga
    31861 aaagtacaat cttgaactac taaaggattt aggcttagat gtaaaaaatt atctttttga
    31921 tattgaagct ggtatcaaag taaatgagta tatcgaatct gcgattacgc ttgattcaac
    31981 gtcaatcaag accaagttcg acaaaattgc tccaatatta caaactattc atacgtctgc
    32041 taaggaatta agaggagaat ttgctccttt tgaagaaatc aaaaaatacg aatccttgat
    32101 tgaagaacaa attccttatg ccaactatga atctgttaga aatgcagtct tctccttaga
    32161 gaaaagactg gctgacttag gtgttgacag aaaatcttgt catatcgatt tggtgcctga
    32221 aaactttatc gaatcacctc aaggacgact ttatttgatt gactgggaat attcatcaat
    32281 gaatgatcca atgtgggatt tggctgccct ctttttagag tctgaattca cttcccaaga
    32341 ggaagaaact ttcttatctc actatgagag tgaccaaaca ccggtttctc atgaaaagat
    32401 tgctatttat aaaattttac aagatactat ttggagtcta tggactgtct ataaggaaga
    32461 gcaaggtgaa gattttggtg actatggtgt gaatcgttac caaagagctg ttaaaggttt
    32521 ggcttcttat ggaggttcag atgaaaagta aaaacggagt tccttttggc cttctctcag
    32581 gtattttctg gggcttgggt ctaacggtta gtgcttatat cttttcgatt tttacagatt
    32641 tgtcaccctt tgtggtggct gcagctcatg attttttgag catctttatc ttactagctt
    32701 ttctcttggt aaaagaaggg aaagttcgcc tctcaatttt cttaaatatt cgcaatgtca
    32761 gtgttatcat cggagccttg ctagcaggcc ctatcggtat gcaggccaat ctttatgcag
    32821 ttaagtatat cggaagttct ttagcttcat ctgtatcggc tatttaccct gcgatttcag
    32881 ttctattggc tttcttcttt ttgaagcaca agatttcgaa aaatactgta tttgggattg
    32941 tcttgattat tggagggatt attgcccaga cctataaagt tgaacaggtt aattctttct
    33001 acattgggat tctttgtgct ttggtttgtg ctattgcatg gggaagtgag agtgttctta
    33061 gctcttttgc catggaaagt gaattgagtg aaatcgaagc cctcttaatc cgtcaagtaa
    33121 cttcgttctt gtcctatctt gtgattgtgc tcttctctca tcagtcattt actgcagtag
    33181 ccaatggaca attgctaggt ctcatgattg tttttgcagc ctttgatatg atttcctact
    33241 tggcttatta tatcgctatc aatcgcttgc aaccagccaa ggctacaggc ttgaacgtga
    33301 gctatgtagt atggacggtc ttgtttgcag ttgttttctt gggtgcaccg ctagatatgc
    33361 tgaccattat gacgtcactt gtcgtcattg ctggagttta tattattatt aaagaataaa
    33421 ggagattcgt gtgaaagcca tcatcttagc agcgggattg ggaactcgct tgcgtcctat
    33481 gactgaaaat acccctaaag ccttggttca ggttaatcaa aaacctttga ttgagtacca
    33541 aattgagttt ctcaaagaaa aaggaatcaa tgacatcatc atcattgttg gttatcttaa
    33601 agaacaattc gattacttga aagagaaata cggtgttcgt ctcgttttca atgataaata
    33661 cgctgactac aataactttt actctctcta tcttgtaaaa gaagaattag ccaatagtta
    33721 tgttatcgat gccgataact atctctttaa aaatatgttc cgcaatgatt tgacacgttc
    33781 tacttatttt agtgtctatc gtgaagattg taccaacgaa tggttcttgg tctatggaga
    33841 tgactacaag gttcaaaaca ttattgttga tagcaaggca ggtcgcatcc ttagtggtgt
    33901 atccttctgg gatgctccaa cagcagaaaa aattgttagc tttatcgata aggcttatgc
    33961 aagcggcgaa tttgttgatc tctattggga caatatggtt aaggataaca tcaaagagct
    34021 agatgtctat gttgaagaat tagaaggcaa tagcatttat gagattgata gtgtccaaga
    34081 ctatcataaa ttagaagaaa ttcttaaaaa cgaaaattaa aagcttccaa catctgacaa
    34141 aatagtcgga tgtttttttg attttttacg aacttttacg aatagataga tgagtagaaa
    34201 aagaaatgga gttatttatg aaaatcacaa actatgaaat ctataagtta aaaaaatcag
    34261 gtttgaccaa tcaacagatt ttgaaagttc tagaatacgg tgaaaatgtt gatcaggagc
    34321 ttttgttggg tgatattgca gatatatcag gttgccgtaa tccagccgtt tttatggaac
    34381 gttattttca gatagacgat gcgcatttgt cgaaagagtt tcaaaaattt ccatctttct
    34441 ctattttaga tgactgttat ccttgggatt tgagtgaaat atatgatgcg cctgtacttt
    34501 tattttacaa gggaaatctt gacctcctga aattcccgaa ggtagcggtc gtgggcagtc
    34561 gtgcttgtag caaacaggga gctaaatcag ttgaaaaagt cattcaaggc ttggaaaatg
    34621 aactggttat tgtcagtggt ctggccaagg gcattgacac agcagctcat atggcagctc
    34681 ttcagaatgg cggaaaaacc attgcagtga ttggaacagg actggatgtg ttttatccta
    34741 aagccaataa acgcttgcaa gactacatcg gcaatgacca tctggttcta agtgaatatg
    34801 gacctggcga acaacctctg aaatttcatt ttcctgcccg taatcgcatc attgctggac
    34861 tttgtcgtgg tgtgattgta gcagaggcta agatgcgttc aggtagtctc attacgtgtg
    34921 agcgagcaat ggaagaagga cgcgatgtct ttgctattcc tggtagcatt ttagatggac
    34981 tatcagacgg ttgccatcat ttgattcaag aaggagcaaa attggtcacc agtgggcaag
    35041 atgttcttgc ggaatttgaa ttttaaaaat gacctaagct agaattctaa gaaaaaatca
    35101 attttaagag aaaatgaacc caacatttcc ataataaaac gcatattagc aagtttttaa
    35161 cacttgataa tatgcgtttt ttctaagtgg attagtagag tagaggattt ttctcatata
    35221 atactcttcg aaaatctctt caaactacgt cagcttccat ctgcaacctc aaaacagtat
    35281 tttgagctga cttcgtcagt cttatctaca acctcaaagc agtgctttga gcaacctgtg
    35341 gctagcttcc tagtttgcgc tttgattttc attgagtata agggaaagta tagtgaattg
    35401 aaataagatg tgaacaactc tatcaggaaa gtcaaattaa tttatagaaa tattttagca
    35461 gccaaggtgc actgttatag attcaataca ctataattta gtgtaattga gaaaggagaa
    35521 atgattgtga ttgatgttgg ctaggttatg ttcaatgatt cctaccgtct caaatcttgt
    35581 cagtaaggaa aaataaattc ttcaaaagta gagattacaa ggcttgttta agaaagaatt
    35641 caaagacctt gacaaataaa aataaaatgg ttattataaa aaatggtctg aaatagatga
    35701 tgatactttt cgaaaatctt tttacgtcag ctcagctttg ccttgctgtg ttttgagcaa
    35761 gctacggtta gcttccgagt ttgattttca tttactagaa atgaaactga tgagagatat
    35821 cagtagacat ttgagtcagg atattatgga aaatgataaa aagagctcgt gagattggca
    35881 tatcagacta ctaaagtatt gagtttgtta ggattttagc gactagttag ctgggaaagg
    35941 aagatatttg tgacaaataa taaactgtat tcgttgatag aatttagaaa taaaatatat
    36001 gaagaattag aactttccag aagtgattta gcgattttac tatgtgccat gcttatcgcc
    36061 tctatcggat taaatatgga ttcgactccc gtgattattg gagccatgtt aatctctcct
    36121 ttgatgacac ctattctggg agtggggctc tctctagcta tatttgattt taaattgtta
    36181 agaaaatctt ttaaaatatt agctattcaa attcttgcca gtttaatagc ttcaacactt
    36241 tatttttatc tttctcccat ttcgtatgct agttcggaaa ttgttgctag aacctctccg
    36301 actatttggg atgttctcat tgcttttgta ggagggatag caggtattat tggtgctagg
    36361 aaaaaagaga ccaataatat tgttcctggt gttgctattg caaccgcctt gatgcctcct
    36421 ctttgtacag taggttatgc tattgcttct gctaatctaa aatttatcat aggctcctct
    36481 tacctattcc tcatcaattg tagctttatt gtcattgcga cttatatagg tgttaggttg
    36541 atgatggtta agaaacatta ttttaaagat aatgaagaag actctaaaat gcgtaggatt
    36601 ttgcttctag ttgctgtttt gctgatgatt ccgagtttca tctctgcaac gactttagtg
    36661 agagaaacgt tgaaaaaaga gtcccttaag aaatttatat cagagcagtt tcaggggcat
    36721 aatattttga aaaaaaccta ttctaaaaag actcataccc taaagctaac catttcagga
    36781 aattatttga cagaagaaga actcgatatg atttcaagta agagaggtga ctatggttta
    36841 agtgatgttt ctgttcaagt ttcacaattg tctgattcag aacaacttag taaggaagaa
    36901 ctggtggagt atttcttcca gtatatcaag gataaggaag caaaagaaaa ggaaaaagct
    36961 aataagtttt atacagagtc tgaggagcaa taatttcttg agaatagctg gtttctctcg
    37021 tgagtcttct atgtatatca aaggaagact gaggttttaa gtataaaact tttcttctat
    37081 tatagtagct aagtcttgac agggttcaaa aaatggttta cactttataa agtttattac
    37141 tttgaaaagg tgtgatactg tggctacggc aacaaaaaag aaaaaatcaa cagttaaaaa
    37201 aaatctagtc atcgtggagt cgcctgctaa ggccaagacg attgaaaaat atctaggcag
    37261 aaactacaag gttttagcca gtgtcgggca tatccgtgat ttgaagaaat ccagtatgtc
    37321 cgtcgatatt gaaaataatt atgaaccgca atatatcaat atccgaggaa aaggccctct
    37381 tatcaatgac ttgaaaaaag aagctaaaaa agctaataaa gtttttctcg cgagtgaccc
    37441 ggaccgtgaa ggagaagcga tttcttggca tttggcccat attctcaact tggatgaaaa
    37501 tgatgccaac cgtgtggtct tcaatgaaat caccaaggat gcagtcaaaa atgcttttaa
    37561 agaacctcgt aagatcgata tggacttggt cgatgcccaa caagctcgtc ggatcttgga
    37621 tcgcttggta gggtattcga tttcgcctat tttgtggaag aaggtcaaga agggcttgtc
    37681 agcaggtcgc gttcagtcca ttgcccttaa actcatcatt gaccgtgaaa atgaaatcaa
    37741 tgccttccag ccagaagaat actggacagt tgatgctgtc tttaaaaagg gaaccaaaca
    37801 atttcatgct tccttctatg gagtagatgg taaaaagatg aaactgacca gcaatgacga
    37861 agtcaaggaa gtcttgtctc gtctgactag taaagacttt tcagtagatc aggtggataa
    37921 gaaagagcgc aagcgcaatg ctcctttacc ctataccact tcatctatgc agatggatgc
    37981 tgccaataaa atcaatttcc gtactcgaaa aaccatgatg gttgcccaac agctctatga
    38041 aggaattaat attggttctg gtgttcaagg tttgattacc tatatgcgta ccgattcgac
    38101 tcgtatcagt cctgtagcgc aaaatgaggc ggcaagcttc attacggatc gttttggtag
    38161 caagtattct aagcacggta gcaaggtcaa aaacgcatca ggtgctcagg atgcccatga
    38221 ggctattcgt ccgtcaagtg tctttaatac accagaaagc atcgctaagt atctggacaa
    38281 ggatcagctc aagctatata cccttatctg gaatcgtttt gtggctagcc agatgacagc
    38341 ggccgttttt gataccatgg ctgttaaatt gtctcaaaat ggagttcaat ttgctgccaa
    38401 tggtagtcag gttaagtttg atggttatct tgccatttat aatgattctg acaagaataa
    38461 gatgttaccg gacatggttg ttggagatgt ggtcaaacag gtcaatagca aaccagagca
    38521 acatttcacc caaccgcctg cccgttattc tgaagcaaca ctgattaaaa ccttagagga
    38581 aaatggggtt ggacgtccat caacctatgc gccaaccatt gaaaccattc agaaacgtta
    38641 ttatgttcgc ctggcagcca aacgttttga accgacagag ttgggagaaa ttgtcaataa
    38701 gctcatcgtt gaatatttcc cagatatcgt aaacgtgacc ttcacagctg aaatggaagg
    38761 taaactggat gatgtcgaag ttggaaaaga gcagtggcga cgggtcattg atgcttttta
    38821 caaaccattc tctaaagaag ttgccaaggc tgaagaagaa atggaaaaaa tccagattaa
    38881 ggatgaacca gctggatttg actgtgaagt gtgtggcagt ccaatggtca ttaaacttgg
    38941 tcgttttggt aaattctacg cttgtagcaa tttcccagat tgccgtcata cccaagcaat
    39001 cgtgaaagag attggtgttg agtgtccaag ctgtcatcag ggacaaatta ttgagcgaaa
    39061 aaccaagcgt aatcgcctat tctatggttg caatcgctat ccagaatgtg aatttacctc
    39121 ttgggacaag cctgttggtc gtgactgtcc aaaatgtggc aacttcctca tggagaaaaa
    39181 agtccgtggt ggtggcaagc aggttgtttg tagcaaaggc gactacgagg aagaaaagat
    39241 taaataagag gaggggcccg aaagtaaatt tcaggctcct tttggttaga acttgacaaa
    39301 atacatcatt ttatgcgaaa ctagaagaag attattttat actcaatgag aatcaaagag
    39361 caaattagaa agctagtcgc aggttgctca aagcactact ttgaggttga agatggaagc
    39421 tgacctggtt tgaagagatt ttcgaagagt attaactagg agaagttatg cgtattatct
    39481 atctaattat tggtttttta tcgctgacct tggctattgt tggggttgtt ttacccttgt
    39541 tgcctacaac acctttcctt ttgttgtcta ttgcttgttt ctccagaagt tccaagcgat
    39601 tcgaagattg gctttatcat accaagctct atcaagcata tgtagctgat tttcgtgaga
    39661 ccaagtctat tgcgcgtgaa cgaaagaaaa aaatcatcgt ctctatctac gtcttgatgg
    39721 gaatttctat ttattttgca cctcttttac cagtcaaaat cggtctgggt gctttgacca
    39781 tctttattac ttattatctc ttcaaggtca ttccagacaa agaatagtta aaacagtagt
    39841 tatttgcctt gataaaattg aaagcatatt cataacaata tgatataata aaattgaagt
    39901 aatattcaag gagaatcaaa tgatttacga attttgtgct gaaaatgtga ctttacttga
    39961 aaaagcgatg caggctggag ctcgtcggat tgaactctgt gataatctag cagttggtgg
    40021 gacaacaccc agctatggag tgactaaggc agcggttgaa ctggcagcta actacgatac
    40081 aaccatcatg accatgattc ggccacgtgg tggtgacttt gtctataatg acctagaaat
    40141 tgctatcatg ctagaagaca ttcgtttgac tgctcaggct ggaagtcaag gggttgtatt
    40201 tggagcttta actgctgata aaaagttgga taagcctaat ctggaaaagt taattgctgc
    40261 atcaaaagga atggaaattg tctttcacat ggcctttgat gaactaagtg atgaagatca
    40321 accggaagct attgactggc tcagtcaagc cggtgtcact cgtatcctaa ctcgtgctgg
    40381 tgtgtctggc gactccttag aaaaacgttt tgttcactat cacagaattt tggagtacgc
    40441 taaaggtaaa attgaaattc taccaggtgg ggggattgac cttgaaaacc gtcaaacctt
    40501 tatcgaccag gtgggggtaa cacaattgca tggtactaag gttgtttttt aaaaaataga
    40561 aaggaactgc tagctttggg tagcagtttt cacttatgtt tgaaattttt aaatcctatc
    40621 aatttaatca agaaaaggct catgattatg gttttataga aaatagcgaa gtctggacat
    40681 atagttgcca gattttgcaa ggtgactttg tcatgactgt gtccatcact gctgataatg
    40741 tgaactttca agtctttgac caagagactg gtgacctcta tcctcacgtt tatatggaaa
    40801 gcatgagggg aagttttgtc ggaaatgtcc gtgaggcttg tctggagatt ctttaccaga
    40861 ttcggaaggc ttgttttgat gtgcaagatt ttatctgtca tcagactaag cgtatcatga
    40921 ctcaagttca ggaaaagtat ggaaaccagt tggagtatct gtgggaaaaa tcgcctgata
    40981 cagctgtatt gcgccatgaa ggcaatcaaa agtggtatgc cgtcttgatg aaaatctctt
    41041 ggaataagct ggaaaagggc agagaaggac aagtggaagc agtcaacctc aagcatgacc
    41101 aagtagctaa tttgctttca caaaagggga tttatccagc cttccatatg agcaagcgct
    41161 actggattag tgtgtccctt gatgatactt tatcagatga agaagtactg gaattgatag
    41221 aaaaaagttg gaacttaacc tctaaaaaat gaaatatttt aataattttc atgaactttc
    41281 aattagctaa atattcttta ctgaagagat ttttagaaaa tataggattt accacactag
    41341 aggaatatgg tgccatcttc aaatacctga ttgagaatgt caagacggat cgtcagatca
    41401 tctattcgcc tcactgtcat gatgacctcg gaatggcagt ggcaaatagc cttgctgctg
    41461 tcaagaatgg tgcaggacgt gttgaaggga ctatcaatgg tattagggag cgagctgaaa
    41521 atgctgcttt ggaagaaatt gcagtggctc tcaatattcg ccaagattac taccaagtag
    41581 aaaccagtat tgtcctaaat gagaccatca atacgtcaga aatggtttct cgcttctctg
    41641 gtattccagt tcctaaaaac aaagccgtcg ttggtggcaa taccttctcc cacgaatctg
    41701 gtattcacca agatggagtc cttaaaaatc ctctcactta tgagatcatc acacctgaat
    41761 tggttggtgt taagattctg cttggaaaat tatctggtcg ccatgctttt gttgagaaac
    41821 tgagagaatt ggccctagat tttacagaag aggatatcaa accactcttt gctaagttca
    41881 aggcactggt cgataagaag caagaaatca cagatgcaga tattcgagct ttggtagctg
    41941 gaaccatggt tgaaaatcca gaaggcttcc actttgatga tttacaactt caaactcatg
    42001 cagataatga cattgaagcg ctcgttagcc tagccaatat ggatggtgag aaagtcgaat
    42061 ttaatgcgac agggcaaggt tccgttgaag caatctttaa tgctatcgat aagttcttta
    42121 accaatctgt tcgtttggtg tcctacacta tcgatgcggt aacagatgga atcgataccc
    42181 aggatcgggt tttggtcact gttgaaaaca gagatacaga aaccatcttt aatgcagcag
    42241 ggcttgattt tgatgtgttg aaggcttctg ctattgtcta tataaacgct aatacctttg
    42301 ttcaaaaaga gaatgcaggt gagatgggac gcagtgtttc ttaccacgat atgcctagtg
    42361 tgtaaaggag aaggctatgg caaagaaaat agtagctcta gcaggagacg gaattggccc
    42421 agaaatcatg gaggttggtt tagaagttct ggaggctcta gctgaaaaaa caggttttga
    42481 ctatgagatt gacagacgac cgttcggagg tgcagatatt gatgcagcat gacctccctt
    42541 acctgatgaa acccttaagg caagtaggga agcagatgct atcctactag tagctatcgg
    42601 tagtcctcag tatgatggag cagtggttcg ccctgaacaa ggcctgatgg ctctccgtaa
    42661 ggaactcaat ctttacgcta atattcgtcc tgtaaaaatc tttgacagtc tcaagcattt
    42721 gtcactactc aaactggaac gaattgctgg tgtagacttt gtcgtggtgc gtgaattgac
    42781 aggcgggatt tactttggag atcatattct tgaagagcgc aatgcgcgtg atatcaacga
    42841 ctatagctat gaggaagtgg agcggattat tcgcaaagcc tttgaaattg caagaaatcg
    42901 cagaaaaatc gttactagta tcgataagca aaatgttcta gcgacctcaa aactctggcg
    42961 gaaagtagct gaggaagtcg cacaggattt cccagatgta accttggaac atcagctggt
    43021 agactcagct gctatgctta tgattaccaa tcctgctaag tttgatgtta ttgtaacgga
    43081 gaatcttttt ggagatattt tatctgatga atcaagcgtc ttatctggta cacttggggt
    43141 tatgccatca gccagtcatt ctgaaaatgg accaagtctc tatgaaccta ttcacagttc
    43201 agcacctgat attgcaggtc aaggaattgc caatcctatt tccatgattt tatcagtttc
    43261 catgatgttg agagatagtt tcggacgtta tgaggatgca gagcgtatca aacgtgctgt
    43321 tgagacaagt ctggcggcag gaattttaac gagagatata ggaggtcagg cttcaacaaa
    43381 ggaaatgacg gaagctatta ttgcaaggtt atgaagttag acgaaaaaat tactctagtc
    43441 cttttgattt ggaatgtcat cattttcttg atttatggta ttgacaaatc taaggcaagg
    43501 agaagagttt ggcgcatccc tgagaaaatc ttacttattt tagcctttac ttttggtggt
    43561 tttggtgcct ggctagcagg aatcatcttt caccacaaga ctcgaaaatg gtactttaaa
    43621 atagtttggt ttcttgggat ggtgaccaca ctagtagcct tatattttat ttggaggtaa
    43681 tggatggcag ggtcttcgag ggaatacgct gcttgggctc tagcggacta tggttttaag
    43741 gtcgtgattg caggatcttt cggtgacatt cattacaata atgaactcaa taatggcatg
    43801 ttgccaatcg ttcagcctag agaggttaga gagaaactag cccagctaaa accaaccgac
    43861 caggtaactg tggacttgga acaacaaaaa atcatctcac cagttgaaga attcaccttc
    43921 gagatagata gcgagtggaa acataaactc ctaaatagtt tggatgatat cggtattacc
    43981 ttgcagtatg aagagttgat tgctgcttat gaaaaacaac gaccagccta ctggcaggat
    44041 tagaaaaaat agaaaaggag atatagtaaa ctgaaataag atgtaaacaa atgaattgga
    44101 gcttaacatc catttccagc aattttttag aaactacagt ggactattct ggattcaaca
    44161 cattataaaa ttatgacaaa acacattcac aagaaggcta cgacatttta aaaggtgagg
    44221 gcggatgtat cgtttgccct actaaagttg gttacattat catgaccagt gacaaggcag
    44281 gacttgagcg taagttcgca gccaaagaac gtaagcgtaa caaaccaggt gttgttctct
    44341 gcggtagcat ggatgaactt tgcgctttag cgcaactcaa cccagaaatt gaagcattct
    44401 actaaaaaca ttgggatgaa gatattcttc ttggttgtat ccttccttgg aaaccagaag
    44461 cctttgaaaa actcaaagca tacggggatg gccgtgaaga acttatgact gatgtacgtg
    44521 gtactagctg ttttgttatc aagtttggaa aagcaggtga acaattggct gccaagcttt
    44581 gggaagaagg taaaatggtc tacgcctcat ctgcttcaat gacaaaacga ttgaaactcg
    44641 ctatgagcaa ggtgtaatgg tgtctatggt cgataaggac ggcaaactca tcccagaaca
    44701 aggaggagca cgttcaactt caccagctcc agttgtgatc cgtaaagggc ttgacattga
    44761 tatagtaaaa tgaagtaaga gcaggacaaa ttaatcagga cagtcaaatc gatttctaac
    44821 aatgttttag aagtagaggt gtactattct agtttcaatc cactataaaa tcatgatgca
    44881 cctgtcagat acttttaact catgggacta ccgtcaggtt gagtattatt aggatagaga
    44941 agaagtctag tgttaaggac attacagctc ataatactag gcttttttat agaaattctt
    45001 ttctttttct ataggatatg gtattctatg tagaaaatat atgttaataa gtaatgccaa
    45061 tatttaaaca tcattagtaa aaggagttag attgatgaat aaaagaaaag ttagtttaga
    45121 agatttttat aaatggtata gtctaaataa agaagagtta ttaaataagg caactgttgg
    45181 tgaaaagttt aatgataaat taaaagaaga gtttctccag gaatggcctt tggataggat
    45241 tttaacaatg tcaatcgatg aatatgtaat aggaaaggga cagcaaaata agtctttatg
    45301 ctacgctctt gagaagggaa aatacaaaaa tctatttctt ggaatttctg gtggctcagc
    45361 ttcaaaattt ggtatttatt ggaataaaaa aacaaacaaa tataaagatc aagctaataa
    45421 tgagatttca gagttggatc agcgattttc aaaattaaaa tcagatttgt atgaaattat
    45481 caaagaaggt attcgtttta actttgaaaa tcctattttt gatatgaaaa gatcaacaaa
    45541 tgaatttatt ggtcgttctg ctatggtgac aaaattactt tgtatctata ctgagggaga
    45601 tcctttcttt ggtgtaaata ttaatagtca gaaagaattt tggaaccact ttgtttctca
    45661 gacaaatcaa ggtggacctt atctgcaaaa tcataaaata attgaactga tgtccaaaac
    45721 ttatcctgag ttggagccat cgaaattagg aactatgctt tttgagtatt ctaagctttt
    45781 tatggaaaat aaggaagaca atagtacaat ggattcatca aacaattttc gtcatcaatt
    45841 aactcaatct ctattaaagt ctccaaacct tatccttcgt ggtgctcctg gcacaggaaa
    45901 gacttatctt gctaaagaaa ttgccaaaga attaacggat ggcaacgaag atcaaatcgg
    45961 atttgtacaa tttcacccat catatgatta tacggatttt gtagaaggtt taagaccagt
    46021 atcaaatggg gatggagcta ttgagtttag gctacaggac ggtattttta aagatttttg
    46081 tcagaaagca aaagaaaccc aattgattgg aggacaagat aattttgatg aggcttggga
    46141 ttcttactta gaatatataa atgttgctga agaaaaagaa tatataacaa aaacatctta
    46201 cttatctgtt aatagtagac aaaatttgtc agtaaattat gatagtggtg ttccaggatg
    46261 gtcactacct ag
//
LOCUS       DAVAZT010000010        45871 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVAZT010000010 DAVAZT010000000
VERSION     DAVAZT010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45871
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.010"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(15..210)
                     /locus_tag="VQT45_000504"
                     /pseudo
     CDS             complement(15..210)
                     /locus_tag="VQT45_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(272..721)
                     /locus_tag="VQT45_000505"
     CDS             complement(272..721)
                     /locus_tag="VQT45_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET2358875.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(723..1481)
                     /locus_tag="VQT45_000506"
     CDS             complement(723..1481)
                     /locus_tag="VQT45_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET2358876.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(1596..3575)
                     /gene="pknB"
                     /locus_tag="VQT45_000507"
     CDS             complement(1596..3575)
                     /gene="pknB"
                     /locus_tag="VQT45_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HET2358877.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(3572..4312)
                     /locus_tag="VQT45_000508"
     CDS             complement(3572..4312)
                     /locus_tag="VQT45_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HET2358878.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVFMNEEDAE"
     gene            complement(4327..5640)
                     /gene="rsmB"
                     /locus_tag="VQT45_000509"
     CDS             complement(4327..5640)
                     /gene="rsmB"
                     /locus_tag="VQT45_000509"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HET2358879.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(5633..6568)
                     /locus_tag="VQT45_000510"
     CDS             complement(5633..6568)
                     /locus_tag="VQT45_000510"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HET2358880.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(6581..8977)
                     /locus_tag="VQT45_000511"
     CDS             complement(6581..8977)
                     /locus_tag="VQT45_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HET2358881.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLKSQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGTVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(9043..9357)
                     /locus_tag="VQT45_000512"
     CDS             complement(9043..9357)
                     /locus_tag="VQT45_000512"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HET2358882.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(9382..10008)
                     /gene="gmk"
                     /locus_tag="VQT45_000513"
     CDS             complement(9382..10008)
                     /gene="gmk"
                     /locus_tag="VQT45_000513"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HET2358883.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(10138..11751)
                     /locus_tag="VQT45_000514"
     CDS             complement(10138..11751)
                     /locus_tag="VQT45_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HET2358884.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(11942..12196)
                     /locus_tag="VQT45_000515"
                     /pseudo
     CDS             complement(11942..12196)
                     /locus_tag="VQT45_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
     gene            complement(12200..12454)
                     /locus_tag="VQT45_000516"
     CDS             complement(12200..12454)
                     /locus_tag="VQT45_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HET2358885.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            complement(12692..13789)
                     /locus_tag="VQT45_000517"
     CDS             complement(12692..13789)
                     /locus_tag="VQT45_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HET2358886.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVLD
                     YQKIADLYTEKGAEMEKFVKNLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKVRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            complement(13799..14539)
                     /locus_tag="VQT45_000518"
     CDS             complement(13799..14539)
                     /locus_tag="VQT45_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2358887.1"
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLELA
                     CGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGKYD
                     FVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHENA
                     EDFAMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQAG
                     FKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(14859..15212)
                     /gene="rsfS"
                     /locus_tag="VQT45_000519"
     CDS             complement(14859..15212)
                     /gene="rsfS"
                     /locus_tag="VQT45_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HET2358888.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(15225..15725)
                     /locus_tag="VQT45_000520"
     CDS             complement(15225..15725)
                     /locus_tag="VQT45_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET2358889.1"
                     /translation="MKTAFIIIDVQNILVETGFQTKSLLGKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            complement(15726..16319)
                     /gene="yqeK"
                     /locus_tag="VQT45_000521"
     CDS             complement(15726..16319)
                     /gene="yqeK"
                     /locus_tag="VQT45_000521"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HET2358890.1"
                     /translation="MSYQDYINCSREALLEKMAEFLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSNQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIANLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            complement(16319..16948)
                     /locus_tag="VQT45_000522"
     CDS             complement(16319..16948)
                     /locus_tag="VQT45_000522"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HET2358891.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(17000..17311)
                     /gene="yhbY"
                     /locus_tag="VQT45_000523"
     CDS             complement(17000..17311)
                     /gene="yhbY"
                     /locus_tag="VQT45_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HET2358892.1"
                     /translation="MSLASKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(17525..18631)
                     /gene="yqeH"
                     /locus_tag="VQT45_000524"
     CDS             complement(17525..18631)
                     /gene="yqeH"
                     /locus_tag="VQT45_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HET2358893.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGTAKVAVWAPEGVAVATRKAII"
     gene            complement(18634..19224)
                     /locus_tag="VQT45_000525"
     CDS             complement(18634..19224)
                     /locus_tag="VQT45_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HET2358894.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            complement(19176..20084)
                     /locus_tag="VQT45_000526"
     CDS             complement(19176..20084)
                     /locus_tag="VQT45_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET2358895.1"
                     /translation="MVLEKQLGHGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(20141..20701)
                     /locus_tag="VQT45_000527"
     CDS             complement(20141..20701)
                     /locus_tag="VQT45_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HET2358896.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            20840..22049
                     /gene="sstT"
                     /locus_tag="VQT45_000528"
                     /pseudo
     CDS             20840..22049
                     /gene="sstT"
                     /locus_tag="VQT45_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            22117..23070
                     /locus_tag="VQT45_000529"
     CDS             22117..23070
                     /locus_tag="VQT45_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET2358897.1"
                     /translation="MSISQRTTKLILATCLACLFAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(23306..23386)
                     /locus_tag="VQT45_000530"
                     /pseudo
     CDS             complement(23306..23386)
                     /locus_tag="VQT45_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(23441..23665)
                     /locus_tag="VQT45_000531"
     CDS             complement(23441..23665)
                     /locus_tag="VQT45_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory protein Asp5"
                     /protein_id="HET2358898.1"
                     /translation="MIEMLIVLAIILSLALIVLVTIQPRQNQLFSMDATSNIGKPSYW
                     QSNTLVKVLTLLVSLALFVLLLTFMVITYK"
     gene            complement(23670..23849)
                     /gene="asp4"
                     /locus_tag="VQT45_000532"
     CDS             complement(23670..23849)
                     /gene="asp4"
                     /locus_tag="VQT45_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory system protein Asp4"
                     /protein_id="HET2358899.1"
                     /translation="MSEEDLFYKDVEGRMEELKQKPIKKEKETRGEKISKTFSLLLGL
                     MILIGLLFTLLGILR"
     gene            complement(23851..25188)
                     /gene="gtfB"
                     /locus_tag="VQT45_000533"
     CDS             complement(23851..25188)
                     /gene="gtfB"
                     /locus_tag="VQT45_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosylation chaperone
                     GtfB"
                     /protein_id="HET2358900.1"
                     /translation="MIELYDSYSQESRDLHESLVATGLSQLGVVIDADGFLPDGLLSP
                     FTYYLGYEDGKPLYFNQVPVSDFWEILGDNQSACIEDVTQERAVIHYVDGMQARLVKQ
                     VDWKDLEGRVRQVDHYNRFGACFAKTTYSADSEPIMTVYQDVNGQQVLLENHVTGDIL
                     LTLPGQSMRYFANKVEFITFFLQDLEIDTSQLIFNTLATPFLVSFHHPDKSGSDVLVW
                     QEPLYDAIPGNMQLILESDNVRTKKIIIPNKATYERALELTDEKYHDQFVHLGYHYQF
                     KRDNFLRRDALILTNSDQIEQVEAIVEALPDVTFRIAAVTEMSSKLLDMLRYPNVVLY
                     QNASPQKIQELYQLSDIYLDINHSNELLQAVRQAFEHNLLILGFNQTVHNRLYIAPEH
                     LFESSEVAALVETIKLALSDVDQMRQALGKQGQHANYVDLVRYQEIMQTVLGG"
     gene            complement(25181..26692)
                     /gene="gtfA"
                     /locus_tag="VQT45_000534"
     CDS             complement(25181..26692)
                     /gene="gtfA"
                     /locus_tag="VQT45_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosyltransferase GtfA"
                     /protein_id="HET2358901.1"
                     /translation="MTIYNINLGIGWASSGVEYAQAYRAGVFRKLNLSSKFIFTDMIL
                     ADNIQHLTANIGFDDNQVIWLYNHFTDIKIAPTSVTVDDVLAYFGGEESHREKNGKVL
                     RVFFFDQDKFVTCYLVDENKDLVQHAEYVFKGNLIRKDYFSYTRYCSEYFAPKDNVAV
                     LYQRTFYNEDGTPVYDILMNQGKEEVYHFKDKIFYGKQAFVRAFMKSLNLNKSDLVIL
                     DRETGIGQVVFEEAQTAHLAVVVHAEHYSENATNEDYILWNNYYDYQFTNADKVDFFI
                     VSTDRQNEVLQEQFAKYTQHQPKIVTIPVGSIDSLTDSSQGRKPFSLITASRLAKEKH
                     IDWLVKAVIEAHKELPELTFDIYGSGGEDSLLREIIANHQAEDYIQLKGHAELSQIYS
                     QYEVYLTASTSEGFGLTLMEAIGSGLPLIGFDVPYGNQTFIEDGQNGYLIPSSSDHVE
                     DQIKQAYAAKICQLYQENRLEAMRAYSYQIAEGFLTKEILEKWKKTVEEVLHD"
     gene            complement(26704..29076)
                     /gene="secA2"
                     /locus_tag="VQT45_000535"
     CDS             complement(26704..29076)
                     /gene="secA2"
                     /locus_tag="VQT45_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system translocase SecA2"
                     /protein_id="HET2358902.1"
                     /translation="MFRRLGQDFQLRKVKKILKQINALKGKMSSLSDQELVAKTVEFR
                     QRLSEGESLDDILVEAFAVVREADKRILGMFPYDVQVMGAIVMHYGNVAEMNTGEGKT
                     LTATMPVYLNAFSGEGVMVVTPNEYLSKRDAEEMGQVYRFLGLTIGVPFTEDPKKEMK
                     AEEKKLIYASDIIYTTNSSLGFDYLNDNLASNEEGKFLRPFNYVIIDEIDDILLDSAQ
                     TPLIIAGSPRVQSNYYAIIDTLVTTLVEGEDYIFKEEKEEVWLTTKGAKSAENFLGID
                     NLYKEEHASFARHLVYAIRAHKLFTKDKDYIIRGNEMVLVDKGTGRLMEMTKLQGGLH
                     QAIEAKEHVKLSPETRAMASITYQSLFKMFNKISGMTGTGKVAEKEFIETYNMSVVRI
                     PTNRPRQRIDYPDNLYITLPEKVYASLEYIKQYHAKGNPLLVFVGSVEMSQLYSSLLF
                     REGIAHNVLNANNAAREAQIISESGQMGAVTVATSMAGRGTDIKLGKGVAELGGLIVI
                     GTERMESQRIDLQIRGRSGRQGDPGMSKFFVSLEDDVIKKFGPSWVHKKYKDYQVQDM
                     TQPEVLKGRKYRKLVEKAQHASDSAGRSARRQTLEYAESMNIQRDIVYKERNRLIDGS
                     RDLEDVVVDIIERYTEEVAADHYASRELLFHFIVTNISFHVKEVPDYIDVTDKTAVRS
                     FMKQVIDKELSEKKELLNQHDLYEQFLRLSLLKAIDDNWVEQVDYLQQLSMAIGGQSA
                     SQKNPIVEYYQEAYAGFEAMKEQIRADMVRNLLMGLVEVTPKGEIVTHFP"
     gene            complement(29069..29509)
                     /gene="asp3"
                     /locus_tag="VQT45_000536"
     CDS             complement(29069..29509)
                     /gene="asp3"
                     /locus_tag="VQT45_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp3"
                     /protein_id="HET2358903.1"
                     /translation="MIITQRQSIYWGEVGGTYMYGTTVSYYLDKSVRLYNPLLPSGEI
                     LKTWFSSVNYQAARTQPQLPLLKRKQEYQLSLVFDCQPENGVYTKITFFDRYGDILEK
                     KVEKAKDFIFTYPEDSYTYQVSLLSAGFESLTFYHFSIKEIRSV"
     gene            complement(29506..31041)
                     /gene="asp2"
                     /locus_tag="VQT45_000537"
     CDS             complement(29506..31041)
                     /gene="asp2"
                     /locus_tag="VQT45_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp2"
                     /protein_id="HET2358904.1"
                     /translation="MSKELNILQIGLANWENHYDIPENMSWYYFYPNSSKTLREIIEK
                     EDINRFHAVLIEDGQYSRDLFSYVKYFEPYTLFYNQNLQINDREVVDFLKKRCAQAID
                     FLSPQQLINDLSKSLFGGGYGDKLFPPTIQVNPNFTGAISYQGLDYVSLEGEFGQDFA
                     QLAYWAYNIMVQKTLPIELWLEYEKEGNCDFRLVIRKMWSGSVDDFFEEVIVSEKDLE
                     QALFMDSRDGDYFLSISVEARGRGTIKLGNLHQRWSRKQFGKFVLGGNILHDSKRDEI
                     NYFFHPGDFKPPLTVYFAGYRPAEGFEGYFMMKTLGCPFILFSDPRLEGGAFYLGTDE
                     LEGKVKDTITHYLDYLGFDHKDLILSGLSMGTFPALYYGASFEPHAIIVGKPLANLGT
                     IASRGRLDAPGVSNLAFDCLIHHTGGTSSQDMTELDQRFWKIFKQANFSKTTFGLSYM
                     KDEEMDPQAYEQLVSYLCNTGAKILSKGTAGRHNDDTDTNISWFLHFYRMVLETGFGR
                     EKR"
     gene            complement(31025..32605)
                     /gene="asp1"
                     /locus_tag="VQT45_000538"
     CDS             complement(31025..32605)
                     /gene="asp1"
                     /locus_tag="VQT45_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp1"
                     /protein_id="HET2358905.1"
                     /translation="MYYFIPAWYGSERTWHADITPWYFSHFRLEFDDTFHQIRLFQEQ
                     DIDSRLLVLAYQPHLRYFLYRHGVLETDTYSVFDVMQDFHNLHTQVLSIRDIEWDDDC
                     EFIYSPFTIIVQKNGKKFAKVEHGVEGFISDIQYFEPNGQIHMHHIMDDRGFISSIIF
                     FEDGQAAYQEYLNPKGVWQFRERLKEGGQVEVNPILGYRFKMLTYQNMGDLVAEFFEN
                     YLQTYVKDQDIFMLPSHSHHDQLVLDRLPSTNPKLLSLFIGRNPQDTFRDLDVTFEKS
                     DLILVDREDSLRLLQELYPERMHQCYHLSSFDTRLRLGRSQTKKESIIYFQLDFEQGI
                     DNQALLQVLSFVAENKDTEVIFGAFAASQEQMNEVEGIVESFIQENIQSENLGKAIDY
                     GDAENPLEENQHQDLRLQFVNLNDELDLIKTLEFVRLIVDLNRHPHLYTQIAGISAGI
                     PQINLVETVYVEHLKNGYLLTDVTEFSKAAHYYTDRLKEWNESLIYSIDKIKEHTGQQ
                     FLGKLEKWIEEVKNVKGT"
     gene            complement(32615..33832)
                     /gene="secY2"
                     /locus_tag="VQT45_000539"
     CDS             complement(32615..33832)
                     /gene="secY2"
                     /locus_tag="VQT45_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein translocase subunit
                     SecY2"
                     /protein_id="HET2358906.1"
                     /translation="MTKIYSSIAVKKGLFTLFLLFIYVLGSRITLPFVDLNTKDFLGG
                     STAYLAFSAALTGGNLRSLSIFSVGLSPWMSAMILWQMFSFSKRLGLTSTSIEIQDRR
                     KMYLTLMIAVIQSLAVSLRLPVQSSYSAILVVLMNTILLIAGTFFLVWLSDLNASMGI
                     GGSIVILLSSMVLNIPQDVLETFQTVHIPTGIIVLLALLTLVFSYLLALMYRARYLVP
                     VNKIGLHNRFKRYFYLEIMLNPAGGMPYMYVMSFLSVPAYLFILLGFIFPNHSGLAAL
                     SKEFMIGKPLWVYVYISVLFLFSIIFAFVTMNGEEIADRMKKSGEYIYGIYPGADTSR
                     FINRLVLRFSVIGGLFNVVMAGGPMLFVLFDEKLLRLAMIPGLFMMFGGMIFTIRDEV
                     KALRLNETYKPLI"
     gene            complement(33889..34566)
                     /locus_tag="VQT45_000540"
     CDS             complement(33889..34566)
                     /locus_tag="VQT45_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HET2358907.1"
                     /translation="MGISVAKGEYITIVDSDDIVKENMIETLYQQVQEKDADVVIGNY
                     YNYDESDGNFYFYVTGQDFCVEELAIQEIMNRQAGDWKFNSSAFILPTFKLIKKELFN
                     EVHFSNGRRFDDEATMHRFYLLASKIVFINDNLYLYRRRSGSIMRTEFDLSWARDIVE
                     VFSKKISDCVLAGLDVSVLRIRFVNLLKDYKQTLEYHQLTDTEEYKDICFRLKLFFDA
                     EQRNGKS"
     gene            complement(34551..34793)
                     /locus_tag="VQT45_000541"
     CDS             complement(34551..34793)
                     /locus_tag="VQT45_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2358908.1"
                     /translation="MSELISVVVPIYNTGKYLVECVEHILKQTYQNIEIILVDDGSTD
                     NSGEICDAFMMQDNRVRVLHQENKGGQHKLKIWGLV"
     gene            complement(34793..35989)
                     /locus_tag="VQT45_000542"
     CDS             complement(34793..35989)
                     /locus_tag="VQT45_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HET2358909.1"
                     /translation="MRKSIVLAADNAYLIPLETTIKSVLYHNRDVDFYILNSDIAPEW
                     FKLLGRKMEVVNSTIRSVHIDKELFESYKTGPHINYASYFRFFATEVVESDRVLYLDS
                     DIIVTGELATLFEIDLKGYSIGAVDDVYAYEGRKSGFNAGMLLMDVAKWKEHSIVNSL
                     LELAAEQNQVVHLGDQSILNIYFEDNWLALDKTYNYMVGVDIYHLAQECERLDDNPPT
                     IVHYASHDKPWNTYSISRLRELWWVYRDLDWSEIAFQRSDLNYFERSNQSKKQVMLVT
                     WSADIKHLEYLVQRLPDWHFHLAAPCDCSEELTSLSQYTNVTVYQNVLHSRIDWLLDD
                     SIVYLDINTGGEVFNVVTRAQESGKKIFAFDITRKSMDDGLYDGIFSVERPDDLVDRM
                     KNIEIE"
     gene            complement(35998..37218)
                     /locus_tag="VQT45_000543"
     CDS             complement(35998..37218)
                     /locus_tag="VQT45_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 8"
                     /protein_id="HET2358910.1"
                     /translation="MRNTKRAVAFAGDYAYIRQIETAMKSLCRHNSHLKIYLLNQDIP
                     QEWFSQIRIYLQEMGGDLIDCKLIGSQFQMNWSNKLPHINHMTFARYFIPDFVTEDKV
                     LYLDSDLIVTGDLTDLFELDLGENYLAAARSCFGAGVGFNAGVLLINNKKWGSETIRQ
                     KLIDLTEKEHENVEEGDQSILNMLFKDQYSSLEDQYNFQIGYDYGAAAFKHQFIFDIP
                     LEPLPLILHYISQDKPWNQFSVGRLREVWWEYSLMDWSVILNEWFSKSVKYPSKSQIF
                     KLQCVNLTNSWCVEKIDYLAEQLPEVHFHIVAYTNMANELLALTRFPNVTVYPNSLPM
                     LLEQIVIASDLYLDLNHDRKLEDAYEFVLKYKKPMIAFDNTCSENLSEISYEGIYPSS
                     IPKKMVAAIRSYMR"
     gene            complement(37249..39693)
                     /locus_tag="VQT45_000544"
     CDS             complement(37249..39693)
                     /locus_tag="VQT45_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_1767 family glycosyltransferase"
                     /protein_id="HET2358911.1"
                     /translation="MIKTIVLAGDRNYIRQLETTIKSILYHNRDVKIYILNQDIMPDW
                     FRKPRKIARMLGSEIIDVKLPEQTVFQDWEKQDHISSITYTRYFIADYIQEDKVLYLD
                     SDLIVNTSLEKLFSICLEEKSLAAVKDTDGITFNAGVLLINNKKWRQEKLKERLIEQS
                     IVTMKEVEEGRFEHFNGDQTIFNQVLQDDWLELDKEFNLQVGHDVTAFYNKWENYFNE
                     LVPPSIIHFVSYRKPWTTLIANRYRDLWWEFHDLEWTKILQHHIGEFELTSSLDKEFS
                     CLTLTNSQDLEGIEELVTALPDVVFHIAAWTDMGDKLIKLAVYDNVRLHPQIVPPVLD
                     KLKKSTNLYLDINHGSADENFLKSLQEQEKTLLAFQSTQHGELGQIVFENGKVSFMID
                     TIKDFKKNGHLTCFRQLPSLTCLTFTASQDIEQLDYLAGQLPNVVFQVAAWTAMGPKL
                     YDLSNRYPNIQLYPAISRDKLDELKEKMDAYLDINLLTSTSDIVAEMAHLSKPILAFY
                     KSQNGNNGQRLYSSEHPERMLADLQKLITKDMLEKPLDIIQVKGIDETLDYIIEHNSS
                     LVRFGDGEINMLAGHSIPYQDYDEELVSIMRDIIGQESREDLVVCLPDAFTDRFRFTS
                     WAIPFWKDHMDHYMDFYRELCSDSWYGSTFVSRPYIDFEDKSQAKAQFEKLKSIWENR
                     DLLIVEGATSRSGVGNDLFDEANSIKRIICPSHSAFSRVHEIEQEIEKYAGGRLILCM
                     LGPTAKVLSYNLCQMGYQVLDVGHIDSEYEWMKMGAKTKVKFSHKHTAEYNFDQDIEF
                     IDDETYNSQIVARILN"
     gene            complement(39703..40713)
                     /locus_tag="VQT45_000545"
     CDS             complement(39703..40713)
                     /locus_tag="VQT45_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET2358912.1"
                     /translation="MKLHLTNLYGMAGDSTVILAQNAVQKIASQLGFREVGIYFYNIA
                     SDSPSEMNKRLDGIMASISIGDILVFQSPTWNGFEFDRLLFDKLKDMQVKIICFIHDV
                     VPLMFDSNYYLMKDYMYMYNLSDVLIVPSERMKTRLMEEGLTTKKILVQGMWDHPHDL
                     SLYTPAFKKELFFAGSLERFPDLQNWSQDTPLRVFSNKGEASSSARNLSIEGWKKDEE
                     LLLELSKGGFGLVWGTYQNDGESNQYYTLNISHKVSTYLTAGIPVIVPSSLSTAKFIV
                     DQGLGFVANSLEEVHAIVDKMNLQEYQEMTNRIKTFSYLLKEGYFTKKLLVDAIYHLG
                     VE"
     gene            complement(40742..41617)
                     /locus_tag="VQT45_000546"
     CDS             complement(40742..41617)
                     /locus_tag="VQT45_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2358913.1"
                     /translation="MENELISIVVPIYNVENYLRQCLDSIQKQTYPNFECIMVNDGSP
                     DHSSKICEEFVEKDSRFKYFEKANGGLSSARNLGIECSGGAYITFVDSDDWLEHDALD
                     RLYGALKKENADISIGRYNSYDETRYVYMTYVTDPDDSLEVIEGKAIMDREGVEEVRN
                     GNWTVAVLKLFKRELLQDLPFPIGKIAEDTYWTWKVLLRASRIVYLNRCVYWYRVGLS
                     DTLSNTWSEKRMYDEIGAREEKIAILASSDYDLTNHILIYKNRLQRVIAKLEEQNMQF
                     TEIYRRMMEKLSLLP"
     gene            complement(41657..42535)
                     /locus_tag="VQT45_000547"
     CDS             complement(41657..42535)
                     /locus_tag="VQT45_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exopolysaccharide biosynthesis protein"
                     /protein_id="HET2358914.1"
                     /translation="MKKNHLVGDALILTVSDQIEELDYLLESLPNICFYIAAPVQFSE
                     KIRSLETNYNVRLRTITNEEQLNFLVDTCDFLLDINHFQEVDAIVSKFVQAGKSVFAF
                     DNTVHGNQGQEVFLSSTPDKLVSRVRDYLNEVRVGTNHQEKIIQDGTWNVFKIDDKAH
                     FIVGANVICRNFENFHVSSGKLILHDGVFINNSCSFNCMERIEIGAGTMMGEGVRFYD
                     HDHIYTAEKIEKWQWTTAPIRVGRDCWIGSNVTILKGVTIGDNTIIGAGCLIRNDIPS
                     NSVVYNNGNLVVKRRD"
     gene            complement(42532..44617)
                     /locus_tag="VQT45_000548"
                     /pseudo
     CDS             complement(42532..44617)
                     /locus_tag="VQT45_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000341103.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
     gene            complement(44678..>45871)
                     /locus_tag="VQT45_000549"
     CDS             complement(44678..>45871)
                     /locus_tag="VQT45_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2358915.1"
                     /translation="STSASESASTSASASASTSASASASTSASASASTSASESASTSA
                     STSASASASTSASASASTSASTSTSTSASTSASTSASTSASTSASTSASESASTSAST
                     SASTSASASASISASESASTSASASASTSASASASTSASESASTSASASASTSTSASE
                     SASTSASASASTSASASASTSASASASTSASESASTSTSASESASTSASASASTSASA
                     SASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASA
                     STSASASASTSASASASTSASASASTSASASASTSASESASTSASESASTSASASAST
                     SVSNSANHSNSQVGNASGSTGKSQKELPNTGTESSIGSVLLGVLAAVTGIGLVAKRRK
                     RDEEE"
BASE COUNT        13360 a        10304 c         8235 g        13972 t
ORIGIN      
        1 attcgctaat tgtttttttt agggcgattg atttttactt ccgtcgcatc aatcattacc
       61 gtgtcttcag aactgagagg agttcttgaa atcgtaacac cacctttgaa caagagttac
      121 ttcaacccat tggctccgac ggagtaagtt gctttcgtgg ataccaaaat cagccgcaat
      181 ttcttcataa gtgcggtatt ctcgcacata tagaaagcgt tgttaattta tttatctcat
      241 ttttcagaaa attcttttat ttctgtaaag tctacgatac tcgatgtgtt tttatataat
      301 gatacagtct gagaatcact gttccgctag ccattccaat agagattacc aaagccaaca
      361 tgacaaccaa ggtcgcactt gccagtgctt tattatagtc ccctgtcaca aaaaaggcag
      421 ttgttcggta ggagagataa cctggaacca gcggtgccaa aatggccaag ataaagacca
      481 cagcaggtgt cttataaaga atacttaaaa tctggctgac acaagaacca ataatggctg
      541 caatgaaggt agctacaatg acattggtcg gttccttgag caagagatag attagccaga
      601 cagtcatgcc caaaatccct ccaggtaaga gcatagaccg ttgcacattg agtacgatta
      661 aaaaagtgat aatggcaaga aaacttgcta ctgcttgtaa taaaaaggtt gttagtgtca
      721 tattagttca tcaataccaa ggcgacagaa gttcctgccc ctaaagcgag ggtaatgagc
      781 agggattcaa acatcttact cataccagag tttatgtggt tggtcataat atcacggacc
      841 gcattggtca aggcaatacc tggtacaaac ggcatgaccg caccagctat aatcaaatct
      901 gccgttgaag gaaaacctgt gtagcgagcc caaaactggg caattatccc aaagacaaag
      961 gctccagcaa aggctgtcac aaagggaatt cggataaatt tttccacata gagggaaaag
     1021 gcaaaaccaa ataaggtcgc cactcctgcc ccaagtgcgt cgtagatatt tccgctaaac
     1081 ataactgaaa agaaaggagc actaaaggtc gcagccagag ttacctgcaa cttagtatag
     1141 ggaaggggtt gagcttgcaa ggccgtcaat tgcttaaagg ctgtttctaa gtcaatctgc
     1201 cccccaacta gctgacgaga aatctggttc acatcgcaga ctttttcgat gttataagaa
     1261 gaggaggtca cgcgcttcat gcgcgaaata ttggtatttt caatagagaa aaagatagcg
     1321 gcaggcatgg caaggacatt gcaatccaca atcccctgcg aatgcgcgat tcgaatcatg
     1381 gtatcttcta cacgatggat ttctgagcca cttttaagga gaatagtccc cgctagcata
     1441 atcacatcaa tgacggcatt taattctttt gattcttcca tgctttcctc cttttatcaa
     1501 ctccctctat tctatcacaa atccggactc aaaaaaaatc tttgccatga aatcatgaca
     1561 aagattgatt actcattttg attatccatc tgcttttaag gagtagctga agttgtttta
     1621 ggtttgtaga ttgaaatctt gactctagtc ttattgaggt ctaccttttc acctgctcta
     1681 ggactttgtt caacaaccat gccttctaca ctacctgcag gcgctgtcgt cacttctaca
     1741 acttctatat tagcttcctt aatcccaaca atttgaatca aattgttctt agtaaactcc
     1801 aagctggaac caatgtaact cggcatggca acacttgtaa cttttttagc tactgtcaag
     1861 acaatttgag taggtttact cacatcataa gtcgttccgg cacctggact ttgtttcata
     1921 atcgttcctg gttcgctttc gctggactct tcttcctcta tcttaatcaa attctcagga
     1981 accttcttct gcttgagttc tgagattact tctgtagagt tccgtccaat atagttccct
     2041 aattgaatcg tcgtagcttt tttagctact gtcaaaacaa tttgagttgc cttgctcaag
     2101 tcataggtcg taccttctgg tagactttgc ttcaggaccg ttccagcctc actctcattc
     2161 gactcttctt cctcaatttt aatcaaatta tctggaactt ttttctcttt taattccgcg
     2221 ataacatcag aagatttccg gccgacataa ttactaattt ggaaggattg tttgcctgat
     2281 gagacaacca gattgatttt cgttccttct tttcgaccag ttccagcgcc aggatctgta
     2341 cggataatcc gcccttcttc caccttttca ctagcctctg tcttctcctc accaatctca
     2401 aaattggctt ttttgagcgt tgccttggcc tctgcaactg tctgacctgc cacatctgga
     2461 atggcaatgg ttgcaggagt tctggatagt atccaaataa gagaagctgc caccaataca
     2521 aggctggcca acaaaatcag gtaacgcatc ttaaatctat gttttttcgg tgcttgtggt
     2581 tggtaagttt cctctgtcac agcctggctt gggtttttga ttgatttgtg ttctgtctgc
     2641 gcttgaacct taggaataga tgtcaaggta ctctgagaaa ccttcggcaa ggtcttggta
     2701 tctgccttgc tcgtttcatc aaagattaac ttactttcat ttctacgatt gtaggacaag
     2761 ctactagaca agtccacata catctctgaa accgagcggt agcgattggt caacttttta
     2821 gcagttgcct tgataataac attttctaaa gcctgaggta cagatggatt ttctgcaata
     2881 acggacggca ggggtttctg gaaatgctgg agggcaatgg tcaccgcgct atccccgtca
     2941 taagggatat ggcctgtcaa catctcatag aaaataatcc ccatggcata gatatcactc
     3001 tgcacagtcg ccttcgaacc acgcgcctgc tctggtgaca agtaatgaac tgagcccaac
     3061 atcgagttag tctgggtcag acttgtctct gcaaaggcta cagcaatccc aaagtctgtg
     3121 accttggcag tcccatctgg tgtcaaaagg atattttgag gtttcaagtc cctgtgaaca
     3181 attcctcgag tatgggccaa gcgcatagcc aagagaattt gtcccatgat acggactgct
     3241 tcttcattag aaagaggata atgttccttg atatagcgtt tgaggtccag tccagccaca
     3301 tactccatag ctaggtactg ttgaccgtct tcctcgccaa tatctgttat ccgaacgata
     3361 tgaggatggt ctagatctgc catagctctc gcttcacgct gaaaacgagc tacagctatc
     3421 gggtccgtct ggtagttggt cctcagaacc ttcactgcca cttcttcccc atctaagatt
     3481 aagtctttgg ctaggtagac atccgccatg cctcctcgac caatctgttt gacaatccga
     3541 tagcgtccgg caaaaatctt gccgatttgg atcattctgc atcctcctcg ttcataaaaa
     3601 caagggcaac cgtaatgttg tctaaacctc ctgcattgtt agcaaaacga acaagtgtct
     3661 ccgttttatc tgctaaagga atatcactgg ttacaatatc acgaatctca ctgcctgaaa
     3721 tcatgttggt caagccgtca ctattgagca agagatagtc acctgactca aggataactg
     3781 tcccaaaatc aggctgaatt tcatcttttt gcccaataga ctgggtgata atattttttt
     3841 gcggatgagc ttctgcctct tctggtgtca attgaccagc cttgagcaat tcattaacca
     3901 aggaatgatc gctcgtcaac tgatggtatt cttctccacg aatcaagccg atacgcgaat
     3961 caccaatatg agcatagata gcctgattat caataatagc aaggacttcc aaagtagttc
     4021 ccatgcctct gtaagcttca tcctgaccaa gctggtgaat cttttgattt tcaatttcta
     4081 ggtaatgggc gaaccattca cgcacttcat tgactgtatc gatctgggta tcaacccaag
     4141 ctacacccag gtctgtgacc gccatttcac tagcgatatt ccctgcacga tgacctccca
     4201 tcccatcagc taaaataatc atggtacgtc cagctctatt gacatagtgg ttgacatagt
     4261 cttggttatt tgttcgtttc tgaccaacat ctgttaataa tgaaatttcc atgtgtcagt
     4321 tccttcctaa tccgatatct tgcgaaattg actgatgaag aatccatcac ttccatacaa
     4381 ttcaggtgta atgaggatac agccgtcttt catgatatcc ttacattcat gttctagttt
     4441 tacctgctcg aactcgggat gactctctaa aaaggcctta acgacttgaa aattctcctc
     4501 tgagacgata gtgcaggtgc tataagttat tataccacct ttgcctagta tttgacaaac
     4561 actacctaat atttctaact gaatttcctg caaggacgcg aaatctgccg tttctttatt
     4621 gtatttgata tctggttttc ggcgcaaaag accgattcct gaacaaggag catccaccaa
     4681 aatcttatca aaggaatcct ggtcaaaaaa ctcatgcacc tttctggcat ccaatttttg
     4741 agtttgaacc cgatcttcaa ctcccagacg ttgggcattt tcttgaatta aatccaactt
     4801 gtggtcgtac aagtccagag cagtaacctg acctgtcgta agataagagg ctatatgggc
     4861 tgttttccca cctggagccg cacaggcatc aagcactcgc tcatcacctt gtaaatcaag
     4921 cgtcggagca accaactgac tggactcgtc ttggatggta atggctccat ccgcaaacaa
     4981 attatgccct gcaaaatgcc cctgctcctt aaccagacca gtggttgcta aaagggaatt
     5041 attcgcctcc aacaaggctt ggatttcctc ttttcgactt aggtctgtta cacgaatact
     5101 ggctttgttt cgcactaaca ggctttcaaa gatggctttt gctctctcct ctccgtattc
     5161 ttccttgagt ttggcaacta gccaaactgg gagagaatag gcaatggagt cacgcttgtt
     5221 ttttcgcttg atgctagcaa tatctggcca gccttcacgc aagatacggc gaaggacagc
     5281 gttgaccaat ttttcactgc cttttttacg gagtttggcc aattccactg cttcattgac
     5341 cacagcatga tctggaatct tgtccaaata gcggagttgg taggcactca tgagaagaag
     5401 gacatagagc cagctgtcta actggtctct gtcttcgata aagtgggata ggtaccattc
     5461 cagagtcagt ttacgggcta ccgttccata gactagctcg gtcactaagc ccttgtctgc
     5521 tgcagagagc tgactcccct tgaggtgttt atttaaggca atatttgaat atgcttgatt
     5581 cacaaaaaca tcctctagca ctgctagagc taaacttcta gccgtttcta ctttagtcac
     5641 caaatcgttc tcctacagtc aatgtacgtc caactccatt gaggaaggaa gcaatgtcca
     5701 tcttaggctt accagctggc tgcacttgtt tgagggatag agccccttca gccgttgcga
     5761 caatcaattc tttcttgccg atagagagaa tctcacctgg atttccctga ccttctactg
     5821 gtagggcttc ataaatctta aagcggtcgc ccttaaggaa agtatgggca acaggccagg
     5881 ggttcattcc acgaatttgg ttaaagagtt gacgattggt tttgttccag tccagttttt
     5941 cttcctctgg ctttatattt ggagagaagg taacctgact cgtatcctgc ggttcaggtt
     6001 tgatatcacc agcaatatag gcaggcagag tgtccaaaag caaatcacga ccaactagcg
     6061 ccaatttttc aaacaaggtg ccaacattgt cctcatctgt gatcggaatg ctgcgacgag
     6121 aaatcatatc tcctgcatcc atttccttaa ccatttccat gatggtcaca ccagcttcct
     6181 catccccttg aatcaaggca taatggatag gcgcaccacc acggtgtcta ggaaggaggg
     6241 aggcatgaac gttgacagca aagtccatgc tatcaaggag tttgcttggg agaaactgcc
     6301 caaaagcagc agtcacaatt ccatctgctc ctagcttcat aagttcttcc atctctggac
     6361 ttccagataa tttttcaggt tggtagatag atagtcctgc ttccttggca gcctgcttga
     6421 ctggggtttc ttggataact tttttacgac caacagcacg gtctggctgg gtcacaacgg
     6481 ctagaatttc gtaacggtca tctgtcaaaa gtccttttaa gactgttgct gaaaagtcgg
     6541 gggtccccat aaagattagt tttgtcatat cttctccttc ttataaaaat tgctgcggct
     6601 catggtcaat gctgagacgg agctcactat tttcccgttc ttgagtcaag gccaagacct
     6661 ggttgagggt cggccccagc tcatcttcta aacggtattt aattaaaatc tggtaatgat
     6721 agaggttgtg ggtacgggca atcggttttg gcgttggccc cagaatggga ctggtctctg
     6781 acaagcctga ccgcaaaatg ttcatgactt cataggcacg tttgaaaacc tcttcttctt
     6841 tcttgtgaga aagggtaata ccaatcgtga aatagtaagg tggatagccg agttgtcgtc
     6901 tgattcccat ttcataggca taaaagcctt cgtaatcttg atccttggca aatcgaatag
     6961 catagtgctg cgaattgtag gactgtatca agacttgacc tgctttttca gcccgacctg
     7021 ctcgacctgc cacctgagtc aagagctgga aggttctctc agaagaacgg aaatcaggca
     7081 gattcaaggc cgtatccgca tttagaactc cgactagggt aacattggga aaatccaaac
     7141 cctttgcaat catctgagta ccaagtaaaa tatccgcttc ccctcgccca aactggtcaa
     7201 gcaaggcttg gtgactgcct ttctttcgag tcgtatccac atccatcctc aaaatgcgag
     7261 cttggggaaa gagttctgct agctcatcat aagccttctg agttcccgtc ccatagtaac
     7321 gaatactgcg gctcttacag ttaggacaga cctgaggaat atccttcgag aaaccacaat
     7381 aatggcagtt catagtcttg gtatccatat gcaaggtcag agaaatatcg cagttgggac
     7441 aagtatccac cgtcccacac tcccgacaca tgacaaagct agaataacca cggcgattga
     7501 gcatgagaac cacctgctct tttttaacca gacggtcttg gatagcctct agcaaaggag
     7561 gcgtaaagtt tgacgtctca ttttgtccga tatagtctcg aaagtcaatc acttgaacct
     7621 cagggattgt agccaaagga ttggcacgtt gggttagacg taagtgttga tagacgcctt
     7681 tgccagcacg tgcccggctc tctaagctcg gcgttgcaga tccaagtacc agagttgctt
     7741 gattatactg agcccgtaaa atagctacct ctctggcatg gtaacgggga ttgctgtcct
     7801 gcttataagc cgcttcatgc tcttcatcaa taatcatgac acccagattt ttcagaggag
     7861 caaagatagc agatctggca ccaacaacaa cttgggcatc gccacgctcc accttgcgcc
     7921 attcatcata cttttcgcca ttggataatc ctgagtgaag aatggctacc ttgtccccaa
     7981 aacgtgctat aaaacgctcg gtcatctgag gagtcaagga aatctcaggt accagcaaaa
     8041 tagctgtctt acccttatcc agggcacctt ggataatctg caagtaaacc tcggtcttcc
     8101 cacttcctgt aatcccttga agtagaaagg gaggttgaga actgccaata gaactcacaa
     8161 ccgcatcacg cgcctgtctt tgttctggat ttaactccaa aggtctactt gcttcaattc
     8221 cttcaaaata agcagccgag cgttgaactt ccttttggac tatggtaaca gtaccttgat
     8281 ccacaaagaa gttgacttgc tctcgcgagt aggactctaa caagctagcc aaggaagcgc
     8341 tctctggatg agacagcaga taatctctca gttccaactt tttcttggca cgtgtagaaa
     8401 tctcaacacc ttctaattgg gcatggtcaa cctcatacca agactgggtc ttgaccttct
     8461 tttgatcgac tgcctgatat tccagaccaa gcaggccttt tctagtcaaa cgcatcattt
     8521 cagcttgctt ggcaaggtct agtgaagaaa aggctagcga atcttctgaa ccaaacaggc
     8581 gtactcgttc ttcctgactc aagccttcca gaggatagag aatcttgtca tagctagaat
     8641 tcagaaaccc tggaagcatg gccttgagga tagagatttt gtaggagaag acagatttgc
     8701 gtaactcctc agccagccag agttgttctg gcgtgagaac aggagaaaaa tccagcacct
     8761 ctgcaatatc ttttaaatct tgctccatct cttctccatc tgattgggac ttcaaaccaa
     8821 gaacaatccc ttgaatcagg cgattaccct taccaaaagg cacatgaacc cgcatcccaa
     8881 cttccagcat tccctcaaat tcctccggaa tcctgtaact atagggctgg tccgtctgca
     8941 tcaagggcac atctacgata atcttagcta gggccatctt ctcacctcct ccttgtcagt
     9001 acattcttgc aatagaaaaa ataagattga gtccccccaa ccttaaattt tttcaccatc
     9061 ttctttttct ttagcaattt gctctttgat tttcttttct tcttcttctt tgcggcgttt
     9121 ttcttcttcg atacggcgac gcactgcttc acgttttcct tctggatctg ggtgaattgt
     9181 aacgtttcct gattcgattt cttctaaagc gcgaagagtt gatttttcag acttgaaacc
     9241 ttgagttgct ggggcacctg cttccaattc gtgggcacgt tttgcttcca agattacgag
     9301 tgaatatttt gaaggaacct tgtcgagcaa ggtatcaata gagggtttta acatcatttg
     9361 cttgtaccta ttttctaaat tttatcgggt agttggagat tttggtaaca tctcctgata
     9421 gtgaccaatg acacgatcca cacagaagtg ttctgcttca atcacacatt tgacacgttc
     9481 agcagctagg ggcacctgat cgttgacaat cgcataatca tactcacgca tgagggcaat
     9541 ttcttccttg gccttttcga ttcgttgggc aatcacttct gcactatctg ttccacgacc
     9601 taccaagcga tcttgcaatt catccaaatc tggtggtgtc aggaagataa agacagcatc
     9661 tggaaccttt ttcttgacct gaagagcacc ctgaacttca atttcaagga aaacatcgat
     9721 tcccttgtcc aaggtttcat tgacataggt cagaggagtt ccatagtagt tgccgacata
     9781 ttctgcgtat tccaacatct gtccttgacg aatcagctct tcaaattctt cacgagtacg
     9841 gaagaaatag tcaacaccgt ccacttctcc aggacgttgt gcgcgtgtcg tcatcgatac
     9901 agaatattga aattggtttt cagaactctc aaaaatctct cttctaaccg ttccttttcc
     9961 aacccctgaa ggaccagaaa aaacgattag taagcctcgg tctgccattg tgtctccttt
    10021 tagtcaatct gtgaaataac atttctctag aataatggca aaaagccaga ttatccttta
    10081 cagtctttct atctagtgta acaaaaaagc agtaattttt caactgctct ttcttattta
    10141 tttagcataa tctactgcac gaagctcgcg aatcacggtt accttgatat ttcctggata
    10201 atcgagattg ttttcaattt tcttacgaac tttgtgagcc aagattgtga ctttgtcgtc
    10261 cttgattttt cctggattga ccatgatacg aatttcacgt cctgcttgaa gggcaaagct
    10321 agtttgcact ccttcaaagc cgttagcaat ttcttccaaa tcatggagac gcttgatgta
    10381 gctttcaaga gactcactac gagcacctgg acgggctgcg ctcaaggcat ctgctgcagc
    10441 gacgataact gctatcacgc tctcagcttc aacatctccg tggtgactag caatcgtatt
    10501 caccacaact gggggttcct tgtacttacg ggccaattcc ataccgattt caacgtggct
    10561 accttcaacc tcatggtcaa tggctttccc gatatcgtga aggaatccag cacgacgggc
    10621 aagagccgca ttttcaccaa gttcgctcgc catgatacca gccaacttag caacctcaat
    10681 cgaatggcgc aaaacatttt gtccatatga agtacggaac tgcaaacgtc ccataatctt
    10741 catcaagtct ggatgaaggt ttggcgcacc aatttcatag gcagcagcct caccgtattc
    10801 acgaatctta ttgtcaatct cttgacggtt tttctcaacc aactcttcga tacgagctgg
    10861 atgtatacga ccatctttga gcaacatttc catagtcata cgggcaatct cacgacgaat
    10921 cggatcaaat cctgacaagg tcaccacttc tggtgtatcg tcgataatca catcgacccc
    10981 tgtcaaactt tcaaaggtac gaatgttacg accttcacga ccaataatgc gtcccttcat
    11041 agtatcgtct ggcagatgaa ctgttgagtt tgttgactcc gctacatatt caccagcgat
    11101 acgttgcata gcttgaacca agatgtcctt ggccattttg tcagaacgtt ccttgacctc
    11161 ttgctcagct tcgcgaatgc gactggcaat ctccctggtc aagttttcct ctgtctgagc
    11221 caagataata tctcgtgctt ctgcctgaga cagagcacca atacgctcta gttctgcttc
    11281 tttttgtctt tcgacttcct ctaattgctc ttcacgcgca tcaaggtttt tcgctctatc
    11341 agaaatactt tgttcttttt gttcaagtgt ttgttcttta ctcgtcaaat tgtcgtcctt
    11401 acggtcaagg ctagtagctc tctctgtcaa acgactttcg atttgtttga gttcttgacg
    11461 ttctgatttg aattcagcgt ccacttcttc acggtatttt ctggcttctt ctttggcctc
    11521 caatagtgct tcttttttaa gagacttgct ttcacgtttg gcttcattaa caagtaaatc
    11581 cgcttcacgc tcagcttgtc cacgtaaatt agttgcttct tgttcagcat ttaaaagcat
    11641 caactctgca gcttcctgag atgatttcat cttagctgag atgctgacat atccaatgac
    11701 taaaccaatg atgacggcaa aaacagcaat cgcaagcgac atgatttcca tgtttttacc
    11761 tcattttatt gttattccga atgacataca ttcttttaca ttctaccata aaaaagtgat
    11821 tttcacaaac ctaaaataga atatgttttg gggaatttgg aacacattta ccaaaataaa
    11881 cttgttgttt agaaatagta gtttagtaga gacttgagaa aaagcctact ttgcagtaga
    11941 cttagtaatg atctttaaag gacaagaaag ccacgctatc tccatccatc atataaatca
    12001 agcgattttc tgcatcaata cgccgtgacc aggctccttg gtaatcatat ttgagtggct
    12061 ctggttttcc tattcctgta aatggatcgc gttgaatatc cttgattaat ttattgattc
    12121 tttttagtgt ttttttatct tggttttgtc agtagcaata atctgcccag gcatcttctg
    12181 taaacttgag tagcattcat cactcctcaa tcacatggac ctgagtgctt ccagcacgga
    12241 cttgagccat tcctcgcaaa accttgtctg ataactcctt attttgggcg attctcaggg
    12301 tttcctgaat actgtcccat tcgctctttg aaagaactac aatgtcctca tctggatttt
    12361 tattgaccac cgtcaaaggc tcaaattcat catttacctt cttcatgtag tcctttaaat
    12421 gatttcggaa tgttgagtaa aggactgctt ccataaccat acctcgtttt agctcttttc
    12481 cactattata cacgaaaaga aagaaattgt caggaacttg tacaagattt tcttttctat
    12541 ctatttatac tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag gctgtacttg
    12601 agtacggcaa ggcgacgttg acgcgatttg aatttgattt tcgaagagta ttattcgtaa
    12661 aaaatctcaa aaagcctacc tttcggtaga cttagtttgt ttctattcta atcggcactc
    12721 ttccaaaatt ttgctctgct atacttggct tccctagttg gtaaatctgg tctgcttttt
    12781 gggtcatagc atcccaaggt tctttgccaa ttcggctgac tagattgacc tgtcctttca
    12841 gagacttgag atgttgcctg actttttcag taaatccaag gacatgaatg gcttctggca
    12901 agacattttc tctagcctgt accaaaatat aggtcaatag gcgtctgaca cgcgccttgg
    12961 tgtaacgttt ggtagtcact aactcgacca attcttccac agactgggct gttttaatag
    13021 cttctttaat gcgcacagcc atttcttgat tgacctgata gatggtggtt aggtcgggat
    13081 ttgacaagat ttgatagcgg agcaagggaa aatagtcttc ccagatcacc ttactggcct
    13141 gctcaaatag ggcaacagaa ggcataaaac gttctaagaa atcttggtcc ttctgatgtt
    13201 gacggagggc tgtcgccgag gcaaagtcca catctttatt cacagaatgg taacctgccc
    13261 cctgacgctg aatcggatgc agcttgatat ttcgtcctgc aaccgccttg gcataggcca
    13321 gagcaagaac atgattgggg gtattacctg aaaaatcaag accagcaaat tccttccaca
    13381 tagcttgggt tttctgggga taggaaaggg aatcaggcag atttttcaca aatttctcca
    13441 tctcagcacc tttctctgtg tataagtcag cgattttctg gtaatccaga acttcctctg
    13501 tcccaaaaac tagactatca atgcccaagc gatccaagat atccacagct ccttgaccaa
    13561 agaaatcagc tgcctgaaca ctgactaaaa agggcaattc cactaccaag tctgcgccat
    13621 tttccagcgc catctgggcc cttgtccact tatccacaat agcaggctct ccacgctgca
    13681 tgaaattccc tgacatggca acaattttca gtccctctgc ctgatccagc aggtatttat
    13741 ggccattatg aaaaggattg aactccgcga taatacctgt tatggtcatg ctaatctcct
    13801 acttctgcgc cacaaaaaac caacgggtgc tagtttctgt tggctcctta tcctcaaagt
    13861 ctgcatagag tttgaaggac ttaaatccag cctgttccag caagatatca taggtcaaga
    13921 tctcataggt cctctcctca tgtacttcat cgtggcgact aaaggaaccg tcagcctcct
    13981 tgataaagaa agtcagctca tgcacgatgg agtgaggaac ttcgtcctca tatgtatccc
    14041 aaagcatggc aaaatcttcc gcattttcat ggtaggaata gccagggaat acttcatctg
    14101 tctggtaggt cgagtgcacg tcaaagatga aaactccctc ttcattcagc gcattgtaca
    14161 cgtccttaaa gacgtcccct acttccacct catcctgcat atagcagata gagtccgaat
    14221 aacacgtgac aaaatcgtat ttccctgcct tggacaaatt cagcatatta ccttctataa
    14281 aagcaatctt ttgcttggct gaagttgctc tcttctccgc aatcttcaac atatccgcac
    14341 tcaagtcaag tccagtcaca tcaaaaccag cctgagaaaa gcgcactgat tgaattcctg
    14401 tcccacaagc caattccaag agtttctttc tctccttggt cttaggcaaa tgacgcagag
    14461 aaaaattcgt ccatttgtcg tataaactat cgtccatgac cgcatcatag accgccgcaa
    14521 aggtttcata agtcgccata aaacatgata ccaagtccgc ccgtaattcg atagaaaatt
    14581 aggagcctta cgatggagcc gagctccaag gaaggctatc tattttccga gaattacagg
    14641 acgggttcaa atcctttcta agatacaaag agccttaaaa gcaaagagta cataggaaac
    14701 tttcttccct atcgtcagat acaaagaaag ttacttttta tctcagcttt tagctcgtgt
    14761 tcagtttcga aatgaaacaa acacgaggcc ctttaccttt ctatcaattt ttctaaaata
    14821 agcaaagaaa cccagttgac tacaactgag ttcatcttct aagcaagagc ttctgaaata
    14881 tctactgaat tcgcctcatg ccatagcttc tctagattat aatgggcacg catttcttct
    14941 gaaaagatat gcacgacaac agcaccaagg tccagtaaga cccagcctcc agctgcatcg
    15001 ccttcgacat ggctaccttt aaagcctgct tgagctactt tttcacggat attagctgcg
    15061 atagcgtcca actgacggct attcattgag ctagtgatga caaagtagtc cgtcacacta
    15121 gtcaaatctt gtacatcaag tgcgaggata tcctccgcac gtttctcatc agccgctttc
    15181 acgactagtt ctagtaattc tttttcgttc atttaatcct ctttttagaa aatatgtttg
    15241 taatctagaa catctgcaaa gcgctcctcc caaatgtcct cataaaattc attaatcgtt
    15301 tctgctggaa tgtcatcccc atcaaaggtt gtgacagcac cttctggaac aataagctga
    15361 tagccatatt caaaggcaac cttgacagag gtatccacac aatattctgt ctgcatacca
    15421 cataaaacta atttttcaat cccctgctta tccaagtatt cttttaagcc agtttctttg
    15481 aaaatactgt tatacttctt ctgaaagacc ttttcagcag gttttcgatt taaaagcgca
    15541 gataactgcc aatcttctga tgtttgagct tcagagttct caatatgttg aacatagata
    15601 atttcaatat tcttgcttct agcctggttt tgtaaataag aaatttttcc caatagactt
    15661 tttgtctgga acccagtttc tactaaaata ttctgaacat caatgattat aaaagccgtc
    15721 ttcatttagt tctctttcaa atagtgcaca aaggcgttat aggtttcaag ggtttgggga
    15781 tagatgggga atccctgatg agctagatac tccacggtac gagctgtttc gtaggccacc
    15841 gccttattga gcgatagatt tgcaatctca cgcgccacat ctactccagg aaaggctcga
    15901 ttgtgctcga tatagtctgc gacgtagatg accttatcta ggtctgtcat ttgaccagca
    15961 ccgactgtat ggacttcaat ggctcgcagg atttctgaat catgcaaatc caaatcttcc
    16021 tgaattttgt aaattccgac cataccatgc cagacattat tgccccagtt tttgaggtca
    16081 gggtctagct ggtaacggtc aatcaaggct agaaattcct gatttgacaa ctttttagca
    16141 tagtcatgaa gaagacctgc tagacttgct ttctcaacat ctacaccaaa gcgctgagct
    16201 aattccatag cggcacgctc cacacctaga caatgggtta gacgtttctc aggtagaaac
    16261 tctgccattt tttccaacaa ggcctcacgg gagcagttga tatagtcttg ataggacatc
    16321 agtagagccc ctccttctcg atgtagtcta gcactggctg aggtaggaga aagttgggtt
    16381 tccgaccttg ggcaaggaag tcccgcacca tgctggacga gatatccatg agcggtacgt
    16441 ccacccagat aactggatag gaagtcccta ccttgtagcg tggacgctga acccccacaa
    16501 actgaaccat gtcaaccagt tcatcaattc ggtaccactt aggcagatag tcaaccatgt
    16561 cggcaccgat gataaagtaa taatccgtat ctggattctt ctctgtcaaa atcttcatgg
    16621 tgtcgtaggt gtaggaaata cccttgcgct ccaactcaat ggtttcaatg actaggccgt
    16681 caattccctc aattgccaac tcaagcatct tgagacgatg gtgttcaggg atggtttcct
    16741 ttttatcaac gtgaggaggt tggtattcag gcatgagaag aacttgatcc agtcccaact
    16801 gttgccgtac ttgatccgca acaatgagat gggcattgtg aacagggtta aaattccccc
    16861 ctaaaatccc aacttgtttg cgttttttct ccttgatttc tggctccaac tctaccttgg
    16921 taaagggagt caatagttcg attgtcatag gctagtcccc tttatttctc tataaaaaca
    16981 gttatttgga gtttcggtct tagatttctt tgactttctt agaaatcttg cgattttctt
    17041 tcttgctaga ttgcttaaac aaaatcaaga tgcgtcctat tttttggact gtatccacac
    17101 cgatttcttc ttccaaaatt tcagctactt cgtggatgtt ttcatctgtg ttttgtaaga
    17161 gagtaacctt gattaattca cgcgcatcaa gagcttgacg gacgctggtt ttgatttggt
    17221 cgttgagtcc atttttcccg atttggatga taggtttgag ggtgtgtgcc tggctgttga
    17281 ggaaggcacg ttgttttgat gctaatgaca taattttctt ccttgttttt tgatagttat
    17341 tttaggtggt gagggacggt cggaactaat tttccaaaga tttcatcttt gaaaaatgga
    17401 tttcctgacc tcacaattga gccttggtct caattgtgcc ccttgccaat ctacagattg
    17461 gcaatcacac cacggcaata actatcgcta tatgagctca ctttgttcgc tcagcgattt
    17521 tgttttaaat aattgctttt cgtgtggcga cggcgacgcc ttctggtgcc cagacggcga
    17581 cttttgctgt gcctgttaca cgaatccagc ctaggcctga aatgactagg tctgtcttat
    17641 ctttaatggt aaagacatgc tggactagcc ttgggaaatc ttctttttcc ttgctatttg
    17701 gtggtgtcag aagagttccc aggtgcttat cgtagaaagc actagctcct tcaagcttgc
    17761 tacgatggag tttgagttca ttatcaaaga aagcagtaaa tccttgcttt tctcctgcta
    17821 taaagtcaaa gcgtcccaaa ccacctaaaa atagggtttg ctcaggatta agctgatagg
    17881 tcttaggctt gatttccttt ttaggactga catacttgag gtttttggcc gtcaagtagt
    17941 gagccatctg gtggcggtgg ataattcccg gcgtatcgta aatataagat ccgtcgtcaa
    18001 gcggaatctc tattttgtcc aaggttgtcc ctgggaagcg tgaagtagtg atgacattct
    18061 gatcacccgt gatttcttgg ataatagcat tgattagagt tgattttcca acgttggtca
    18121 caccgaccac atagacatcg cggcccttac ggtagtgttc aatcttatca atgacttcct
    18181 taatggcatg tttattttgt gctgaagtta ggaccacatc gactggacga agaccttctt
    18241 catgggcacg tttcatgagc cactggctaa tcttaccaga cttaactgac ttaggaagga
    18301 tatctttttt atttcctacc aagaggacat cattgcccga gacgaaacgt ggtaaacctg
    18361 ggatgacaga tccattaaaa tcaaagatat caatgacatt gaccactaag gcatcactgt
    18421 ctcccacctc gtgcaagagc ttgaggaaat catcgttcgt caactggaca tctgtgattt
    18481 cattgtagtg gcggagacgg aaacagcgtt ggcaatagac ttcgccagtc tccaaacctt
    18541 tttcaagtgc cgactggggg gtaaaaccaa gaccagcttt atctgtcgtc tgaatggttg
    18601 ctccacaacc aatacagaga atttcttcca tagttaaatt ccttttttat atgtaatcgg
    18661 tccgtacttt tcagtgattt ttctcataac acgacgctca cgagttcggt taatctgcgt
    18721 tttgattgag tcatgttgga ccaagggttt gactaaaatt gaccgaatcc ctgcacggtg
    18781 ggctgctcgt atatctgtca tgagctggtc gccaaccatg accacttcct ttttgtcata
    18841 gtggaattcc ttcatggcac ggtcaatacc aaatgtgaag ggcttcaagg cccagtaaac
    18901 gtaatcaatc ccaaatttct caactgctcg ttgaacgcgt tttttggtgt tatttgacac
    18961 tacgataatg ccaatacccg cgtcccgaag gtcatgtagc cattgcttca tctctggcgt
    19021 tccatcaggg ttgttccaag caatgagggt attatccaaa tcgaccaaaa cagccttgat
    19081 tccctgcgcc tgcaggcttg ggactgtcag atcatagact gcttccacag caaaatctgg
    19141 tatataattt tcaatcgcca ttctggctcc ttttcttaac tttttttcgc aattttcctt
    19201 agtaacaagg ataaaacaat ccacaaacct gcactagcca aactgatata gagccaagca
    19261 tggggctcat ctgttaaagg taagggaaca ttcattccga aaaagcctgt cacgactgcc
    19321 aaaacagcta gcaagactga aatgatagtc aaggttgtca aattgtcatt cagattattg
    19381 tttagaatat tgttgtaaga ggctgaaagc tgctgtaaaa tctgagagat taggtctgtc
    19441 atggatacca gctgatgagc ctcaatcatg gcatcatcaa actgttctct ctcaatctca
    19501 tcaaaactac gatacaaggc atgaccttga atatgctcta acaaaatccg attttgtttg
    19561 gcagctgccg tcagataaac cataccagtc tccaaatcag acagggcaaa gaggtttttc
    19621 ttggtagttc gctggcgcaa gaggtcattg acctcatccc tactcttgtc catctgctca
    19681 atgacaggat agtaggcatt gctgatgatt tccagactgg caaagagaaa cttataaatc
    19741 gaaagcgtgt catggctctc cagataacga gtcatctgtt caatgacata ggcgttcttg
    19801 gtattactaa tggtaatcag gcgacgatgc tcgacgataa aggtcatggg aaaagtctca
    19861 tagtaggcct tgtccttttt tacgtctagg acattataga taaaggtaac cgtcccactt
    19921 tcacggtggt agtccatgtg ggcgcgctcg tttctatcca gtgcgtattc aatggtttcc
    19981 ttgtccaaac cgtaaatttc agaaaggtct tctagtttat tcaactttcc taggtctagg
    20041 tctatccagg tacaaccatg gcccaactgc ttttctaaaa ccatcttttc tccttattaa
    20101 actccctcta ttgtaccaca aattacttaa aataacaggt ctagtctgtg cgtgagaaat
    20161 tgctaacaac tgtgatattt cggttaggga caaagtgaag ggcttgctcc tcgctacgaa
    20221 gctgtgtcgt acgaattccc acactgacaa ccttacccga tacagtaatc ggtccatttg
    20281 tcagaacgac ctcatctccc acatccagtt gacgttcaaa gaggatgaaa aagccattga
    20341 tgacatcaga cagaaagcct tgggctccca taccaatcgc taccccagca ataccagctc
    20401 cagccagcaa actagaaact ggcaaaccta aaatcgacaa aatgcagtag agtaaaaaga
    20461 aatatagcgt ataattaaac acattttcta gtaaacgtga gatggttttt tggcgtccga
    20521 catcatgacg agacattttt agagaaggtt tgacaattct ctgcaccatg gtatgaagca
    20581 tttttttagc aatataaaat acaatcaaaa gcagtaaaag agaaatgacc ttggttagaa
    20641 tattctcgat aatggttgtc acatctagct tttcaatata agcctgaata aatttttgca
    20701 tataaaactc ctttatttca ttataccata ttttcatcag tctcattctc cataaatatt
    20761 caaaaaatag acagaaaatt cttgattttg tctatcattt atactataat cataatcact
    20821 acacaaaaag gagattatta tgaaaagaat cattcatgct tggaataagg caagccttgt
    20881 caagcgtatc ttgattggta tgctttgtgg ggaatcctag gactgaccct tcctaatctc
    20941 tcagggattg ggctactcgg ggatttattc gttggaggtc taaaagctgt tgctcctatc
    21001 ctagtctttg ctctcgttgc caatgccctt tcccaacatc aaaagggaca agatagcaat
    21061 atgaaaactg ttgttttctt gtatatccta tgatagggac tttcgccgct gctcttgtag
    21121 ctgtactagc aagtttcatc gtccctattg aaattaccct aaatagtgcc aatactgaaa
    21181 ttgcaccacc agatgggatt gggcaggtcc tcagcaacct cttgctcaaa ctggttgaca
    21241 gcccagtcaa cgccctgctt actgctaact atattggaat cttatcttgg gcagtcattt
    21301 ttggaatcgc tatgagagaa gccagtaaaa atagtaaaga attgctaaaa actatcgctg
    21361 acgtgacttc taaaattgtc gaatggatca tcaatctgac tccatttgga atccttggtc
    21421 ttgtttttaa aaccatttct gacaagggag tcggaaggct tgccaactac ggtattttat
    21481 tggttctatt agtaacgact atgctttttg ttgcccctgt ggtcaaccct ttgattgcct
    21541 tcttctttat gagacgcaat ccttaccctc tagtttggaa ctgcctccgt gtcagcggtg
    21601 tgacagcctt tttcactcgt agttctgcgg ctaacattcc tgtcaatatg aaactctgcc
    21661 atgaccttgg actcaaccca gatacctatt ctgtttctat cccactcggt tctactatca
    21721 atatggctgg agtagcgatt accattaacc ttttgaccct tgttacagtt aacactcttg
    21781 gaattcctgt tgactttgcc acagcctttg tcctcagtgt ggtagcagct atctcagcct
    21841 gtggtgcttc aggtattgcc ggaggttccc tccttcttat cccagttgct tgtagccttt
    21901 tcggtatttc taacgatatt gccatacaaa ttgttggggt tggttttgtg attggtgtca
    21961 tccaagactc atgtgaaaca gcccttaact cttctacaga tgtcctcttt accgccgttg
    22021 ccgaatacgc agcaacccgt aaaaaataac tcatcaaggc aagcctgctc atgtcttgtc
    22081 ttttacgctt ttattctaac ttattaggaa attcttatgt ctattagcca acgtacgacc
    22141 aagctcatct tagctacctg tcttgcctgc ctgtttgctt attttctcaa tctttcgtca
    22201 gcagtttcgg ctggaattat cgctctcttg agcctatctg atacgcgtag aagtacttta
    22261 aaactggctc gcaatcgtct tttttctatg cttctagctc tggctatcgg tgttctagct
    22321 tttcacttga gcggatttca tatctggagt ctcggcctct atctggcctt ctacgttcct
    22381 ttagcctaca agatgggctg ggaaattggc atcacaccaa gcacggtttt ggttagccat
    22441 ctcttggttc aagagtcaac ctctccagac ctcctagtca acgaattcct tctctttgct
    22501 atcggtacag gatttgcctt gcttgttaat ctctatatgc cttcacgaga agaggaaatc
    22561 cagcactacc acacgctggt ggaagaaaag ttaaaagata tcctccagcg cttcaaatac
    22621 tatttatcca gaggagacgg acgcaaccga gcacagctgg tagcagaatt agacacgctt
    22681 ttgaaagaag ccctcagact ggtctatttg gatcactctg accacctctt tcaccagacc
    22741 gactaccata tccactactt tgagatgaga caacgacaaa gtcgtatcct gagaaacatg
    22801 gcccaacaga ttaacacttg tcaccttgcc gccagtgaaa gcctgatctt agcgcaactc
    22861 ttttcaaaaa ttgcaggtca actgagccag accaatcctg cttctgattt gctagatgaa
    22921 attgaacgtt atctggaagt cttccggaac cgcagtctgc ccaagacaag agaagaattt
    22981 gaaacccgcg ccacccttct tcaactccta cgtgaagcca aaaccttcat ccaagtaaaa
    23041 gttgattttt accaaaaata tagacagtaa tactcttcaa accacgtcag cgtcgccttg
    23101 ctgtatatat gttactgact tcgtcagttc tatccacaac ctcaaaacga tgttttgagc
    23161 tgacttcgtc agttctatcc acaacctcaa aacggtgttt tgagctgact tcgtcagttc
    23221 tatccacaac ctcaaaacgg tgttttgagc tgacttcgtc agttctatct acaacttcaa
    23281 aacggtgttt tgagctgact tcgtcagttc catccacaac cttaaaacag tgttttgagc
    23341 agcctgcggc tagcttccta gtttgctctt tgattttcat tgagtataaa aaagaaaact
    23401 tcagaccaat ccacaaaagg tgaatatctg aagttttctt ttatttataa gtaatcacca
    23461 taaaggttaa tagtagaaca aataaagcca aactcaccaa taaagtgagc accttgacca
    23521 aggtgttgct ctgccagtag cttggtttac caatattact agtggcatcc atggaaaata
    23581 gttgattttg acggggttgt atagttacca atacaatcaa agcaagagat aggataatag
    23641 ctaaaacaat tagcatttca atcattgatc tacctcaaaa ttcccaacaa agtaaagagc
    23701 aaaccaatca gaatcattaa gcccagtaaa agtgaaaaag ttttactaat cttctcccct
    23761 cgggtttctt tttccttctt gatgggtttt tgtttcaact cttccatgcg accttcaacg
    23821 tctttgtaaa ataaatcttc ctctgacatg ttagcctcct aaaacagttt gcattatttc
    23881 ttgatatcgc accaagtcaa cataatttgc atgttggcct tgtttgccaa gtgcctgacg
    23941 catttgatca acatctgaaa gggccaattt aatggtctca accaaggcag caacttcact
    24001 actttcaaat agatgttctg gagcgatata aagtctattg tgaaccgttt ggttaaatcc
    24061 aagaatcaag agattgtgct caaaggcctg acgcactgcc tgcaacaact cattgctgtg
    24121 attgatatcc aagtaaatat ccgacagttg atacagctcc tgaatcttct gtggactagc
    24181 attctggtaa aggaccacat taggatagcg aagcatgtct aagagcttag aagacatctc
    24241 tgtcactgct gcgatacgga aggtaacatc aggcaaggct tctacgattg cttctacttg
    24301 ctcaatctga tctgaattgg tcaagattaa ggcatctcgt cttaggaaat tatcacgttt
    24361 gaactggtaa tgataaccca agtgcacaaa ctgatcatgg tatttctcgt cagttaactc
    24421 taaagcgcgc tcataagtcg ccttatttgg aatgatgatc ttcttagtac gcacattatc
    24481 actttccaaa atcaactgca tattacctgg aatggcatca tagagaggtt cctgccatac
    24541 caagacatcc gagccagatt tatctggatg atggaaggaa accaagaaag gagtcgctag
    24601 agtattaaag ataagctgac tggtatctat ttccaaatct tgcaaaaaga aggtgataaa
    24661 ttcaacttta tttgcaaagt aacgcatgga ctgaccaggc aaagtcaata agatatcacc
    24721 cgtcacatgg ttttccagta aaacttgttg gccattgaca tcttggtaaa ctgtcataat
    24781 cggctcgcta tctgcgctat aagtggtttt agcaaagcaa gcaccaaagc gattgtagtg
    24841 gtcaacctga cgtactcgac cttctaggtc tttccagtct acctgtttaa ccaagcgagc
    24901 ctgcattcca tcaacataat gaatgacagc cctctcctgc gtcacatctt caatacaagc
    24961 agactgatta tctcctaaaa tttcccaaaa atctgaaacg ggaacttggt taaaatagag
    25021 aggttttcca tcctcgtaac ctagataata ggtaaaagga gaaagcagac catcaggcag
    25081 aaaaccatct gcatcgatga ccactccaag ttgagaaaga ccagtagcga ctagactttc
    25141 atgtaaatct ctactttctt gactgtaact atcataaagt tcaatcatgg agcacctcct
    25201 ctactgtttt cttccacttt tctaaaattt ctttggtcaa gaagccttct gcaatttgat
    25261 aagaataggc acgcatagct tccaaacgat tttcttgata caattgacaa atcttagcgg
    25321 cataagcttg cttgatttgg tcttctacat ggtcagatga acttggaatc aaataaccat
    25381 tttgcccatc ctctataaag gtctgattac cataaggcac atcaaaacca attagaggta
    25441 gacctgaacc aatagcttcc atcaaggtca gaccaaatcc ttcgctggta gaagccgtta
    25501 agtagacctc atactggcta taaatctgcg aaagttccgc atgccccttg agttggatat
    25561 agtcctctgc ctgatgattt gcaataattt ctctaagcag agaatcttct ccaccactac
    25621 catagatatc aaaggttagt tccggtaact ccttatgagc ttcaatcaca gctttcacaa
    25681 gccaatcaat gtgcttttct ttggcaagac gtgaagccgt aatcaatgaa aatggtttgc
    25741 gcccttgact tgaatctgtc aaggaatcaa tactgcctac aggaatggta acaatctttg
    25801 gctgatgctg agtatatttg gcaaattgct cttgtagaac ttcattttgt ctatcagtag
    25861 acacgataaa gaagtcaacc ttatctgcat tggtaaactg atagtcataa tagttattcc
    25921 aaaggatata gtcctcattt gtagcatttt cactataatg ctccgcatga acaactaccg
    25981 ctagatgtgc tgtctgtgct tcctcaaaca caacctgtcc aatacctgtc tccctatcca
    26041 gaataaccaa atcagacttg ttcaaattca aagatttcat aaaggcacgc acaaaagctt
    26101 gctttccata gaaaatctta tccttgaaat gataaacttc ttccttccct tgattcatca
    26161 aaatatcata gactggagtc ccgtcttcat tgtaaaaagt tcgttggtat aagactgcaa
    26221 cattgtcctt gggagcaaaa tactcgctac aataacgcgt ataagaaaag taatccttcc
    26281 gaatcaggtt tcccttaaaa acatactcgg catgttgaac caagtccttg ttctcatcaa
    26341 ccaaataaca ggttacaaac ttatcttggt caaaaaagaa tacacgtaaa accttgccat
    26401 ttttttctct gtgactttct tcaccaccaa agtaagccaa gacatcatcc actgtcacgc
    26461 tagtaggtgc aattttgata tctgtgaaat gattataaag ccagataacc tgattatcat
    26521 caaaaccaat attggctgtt aagtgctgaa tattatcggc taaaatcata tctgtaaaga
    26581 taaacttaga ggacagattt aatttccgaa aaacaccagc acgataggct tgagcgtatt
    26641 caacaccgct actagcccaa ccaattccta aatttatatt gtaaattgtc atattttctc
    26701 ctcttatgga aaatgagtca cgatttcacc ttttggagtg acctcaacca gccccatcag
    26761 gagattacgc accatatccg cacggatttg ttctttcata gcttcaaagc ccgcgtaggc
    26821 ttcttgatag tactctacga ttggattttt ctgactagca gattgaccac cgatagccat
    26881 ggatagctgt tgtagatagt ctacctgctc tacccagttg tcatcaatgg ctttaagcag
    26941 tgaaagtcgt aaaaactgtt catataagtc atgttgatta agtaattctt tcttttcaga
    27001 aagttcttta tcaatcacct gcttcataaa gctacgaact gcagttttgt cagttacatc
    27061 tatataatct ggaacctctt taacatgaaa actaatattg gtcacaataa agtgaaacaa
    27121 taattcacga ctagcatagt gatcagccgc tacctcttct gtatatctct caatgatatc
    27181 cacaacaaca tcctctaagt cacgagaacc atctattaga cgatttctct ctttatagac
    27241 tatatcccgt tgtatattca tactttcagc atactccaga gtctgacgac gtgctgaacg
    27301 tccagcacta tcactggcat gctgagcctt ttcgactagt ttccggtatt tacgaccttt
    27361 caatacttcc ggttgagtca tatcttgaac ctgatagtct ttgtactttt tatgcaccca
    27421 agatggacca aatttcttga taacatcatc ctctaaggat acaaaaaatt tactcatacc
    27481 aggatctccc tgacgaccag aacggccacg aatttgtagg tcgatccgct gactttccat
    27541 ccgctcagtc ccaataacaa tcaagccccc aagctctgcg actcctttac caagcttgat
    27601 atccgtacca cgtcctgcca tagaggtagc cactgtcaca gcccccatct gacctgactc
    27661 ggagataatc tgagcctcac gcgccgcatt attagcattt aggacattat gggcaatccc
    27721 ttcacgaaac aagagagacg aatagagttg agacatttca actgagccta caaaaacgag
    27781 taaaggattt cccttagcat ggtattgctt gatgtactcc aaggatgcat acactttttc
    27841 aggtaaagtg atatatagat tatctggata gtcaatccgt tgtctcggac gattggttgg
    27901 aatgcgtact acagacatat tgtaagtttc aataaactct ttttccgcga ccttacctgt
    27961 ccctgtcata ccagatatct tattaaacat cttaaaaaga ctctgatagg tgatcgaggc
    28021 catagcccgc gtctcaggag ataatttgac atgttccttg gcttcaatag cctgatggag
    28081 acctccttga agtttagtca tttccattag acgccctgtt cccttatcaa ccagtaccat
    28141 ctcatttcca cgaatgatat agtccttatc tttagtaaag agcttatgag ctcgaatcgc
    28201 ataaaccaaa tgacgagcaa aagacgcatg ctcttccttg tataaattat caatccctag
    28261 gaaattctca gcagacttgg cccccttagt agtgagccaa acctcctctt tctcctcttt
    28321 aaagatataa tcctctcctt cgaccaaggt tgttacaagt gtatcaatga tcgcatagta
    28381 attagactga acacgaggag aacccgcaat aatcagagga gtttgtgcac tatcaagcaa
    28441 gatatcatca atttcatcaa taataacata gttaaacggt cgtaaaaact taccttcttc
    28501 attcgaggct aggttatcat ttagataatc aaaacctaaa ctactattgg ttgtgtagat
    28561 gatatccgaa gcatagataa gcttcttttc ttcagctttc atttccttct ttggatcttc
    28621 cgtaaatggt acaccaatgg tcaatcctag aaaacgataa acttggccca tttcctcggc
    28681 atcacgcttt gataaatact cattaggagt cacaaccatc actccttctc ctgaaaaagc
    28741 gttcaaatag acaggcatgg tagctgtcaa ggtcttacct tcccccgtat tcatctcagc
    28801 aacatttcca tagtgcatga caatagctcc catgacttga acatcatagg ggaacatccc
    28861 taaaatccgc ttatctgctt cacgcaccac agcaaaagct tcaaccaaaa tatcgtctag
    28921 actttctccc tcggaaagac gctgacgaaa ctctactgtt ttagctacta attcttgatc
    28981 cgaaagagag gacatcttgc ctttcagggc attaatctgc tttaaaatct ttttcacttt
    29041 cctaagctgg aaatcttgac ctaaacgtct aaacacttct gatctccttg atagaaaaat
    29101 gataaaaagt taaggactca aatccagcac ttaaaagaga aacttgataa gtataactat
    29161 cttctggata agtaaatatg aaatctttcg ctttttctac ctttttttct aaaatatcac
    29221 catagcggtc aaaaaaagtt atcttggtat aaactccatt ttcaggctga caatcaaaaa
    29281 ccagtgatag ttgatactcc tgctttcttt ttaataaggg aagctgaggt tgggttcgtg
    29341 cagcctggta attgacacta gaaaaccaag tctttagaat ctcaccagat ggcaatagag
    29401 gattatacag acgaacactt ttgtcaaggt aataagatac agttgttcca tacatataag
    29461 tcccaccaac ttctccccaa taaatagact gtctctgtgt aataatcatc ttttctccct
    29521 tccaaaacca gtctctaaga ccattctata aaagtgcaaa aaccaagaaa tattggtatc
    29581 tgtatcatca ttgtgtcgtc cagcagttcc tttagataaa atcttcgcac ctgtattaca
    29641 cagataagac actaattgtt cataggcttg tggatccatt tcttcatctt tcatatagga
    29701 taaaccaaag gttgtctttg aaaaatttgc ttgtttaaaa attttccaaa aacgctgatc
    29761 caactccgtc atatcttgag aacttgtccc acctgtatga tgaattaaac aatcaaaagc
    29821 taagttagag acacccggtg cgtccaaacg tccacgacta gctatagttc ctaaattagc
    29881 caagggctta ccaactatga tggcatgggg ttcaaaagaa gcaccataat agagagccgg
    29941 aaacgttccc atagaaagac ctgataaaat caaatcctta tgatcaaagc ctaaataatc
    30001 aagatagtga gtgatcgtat cctttacttt tccctctagc tcatccgttc cgagataaaa
    30061 agctcccccc tctaaacgtg gatcagaaaa taaaatgaag ggacatccaa gagttttcat
    30121 cataaagtaa ccctcgaatc cttctgcagg tcgataacct gcaaaataga cagtcaaagg
    30181 cggtttaaaa tcacctggat ggaagaaata gtttatttca tcacgcttgg aatcatgtag
    30241 gatatttcca ccaagtacaa acttaccaaa ttgttttcga ctccatcgtt ggtgaagatt
    30301 acctagtttg atagttccac gacctcttgc ttcaacagat atcgagagaa agtagtctcc
    30361 gtctcgacta tccataaaaa gtgcttgctc caagtctttt tcagatacta ttacttcttc
    30421 aaagaaatca tcaacagacc cactccacat tttacggatt actaaacgaa agtcacaatt
    30481 gccttccttc tcatattcaa gccacaactc aatagggagt gttttttgca ccataatatt
    30541 ataagcccaa taggcaagct gggcaaaatc ttgcccaaac tcaccttcca aactgacata
    30601 atccaatcct tgataagaaa tagctcctgt aaaatttgga ttgacttgta tcgtcggagg
    30661 aaagagttta tcaccatacc caccgccaaa aagagattta cttaaatcat tgattagttg
    30721 ttggggactt aaaaaatcaa ttgcttgtgc acatcgtttt tttagaaaat ccacaacctc
    30781 tctatcattt atttgtagat tctggttata gaacaaagta taaggttcaa aatattttac
    30841 ataggaaaat aagtctctgg aatactgacc atcttctatt aaaactgcat gaaaacggtt
    30901 aatatcctct ttttcgatta tttcacgaag ggtttttgat gagtttgggt aaaaataata
    30961 ccaactcata ttttcaggta tgtcatagtg attttcccaa ttggcaagtc ctatctgtaa
    31021 aatattaagt tcctttgaca tttttaacct cctctatcca tttctctaat tttccaagaa
    31081 attgttgtcc tgtgtgctcc ttaatcttat caattgaata tatcaaggac tcattccact
    31141 ccttcaacct atctgtgtaa taatgtgcag ccttagaaaa ttctgtcaca tctgtcagca
    31201 aataaccatt ttttaaatgt tccacataga cggtttcaac taggttgatt tgaggaattc
    31261 ctgcactaat cccagcaatc tgtgtgtaga gatgaggatg tctatttaaa tccacaatca
    31321 aacggacaaa ttctagtgtt tttatcaaat ctaactcatc attcaagtta acaaactgta
    31381 agcgtaagtc ctggtgttga ttttcttcca ggggattttc tgcatcacca taatcaatcg
    31441 cctttcccag attttcggat tgaatgtttt cttggatgaa agactcaaca atcccttcaa
    31501 cctcattcat ttgctcctga ctagcagcaa aggctccaaa aatcacctca gtatccttat
    31561 tttcagcgac aaaggacaag acttgaagca gagcttgatt atcaatcccc tgctcaaaat
    31621 ccagttgaaa ataaatgatg gattctttct tagtttggct tcgtcccaat cgtaatcggg
    31681 tgtcaaaaga tgataaatga taacattgat gcattcgttc aggatacaac tcctgcaaca
    31741 atcgtaaact atcctctcta tccaccaaaa tcaaatccga tttttcaaaa gttacatcta
    31801 aatccctaaa ggtatcttga ggattacgtc caatgaacag actcaacagt ttaggattag
    31861 tactaggtaa acgatctagt accaactggt catgatgaga atgagaagga agcataaaaa
    31921 tatcctgatc cttcacatac gtttgcagat aattctcaaa aaattctgcc accagatctc
    31981 ccatattttg ataggtaagc attttaaagc gataacccaa aattggattg acttctacct
    32041 gtcctccttc ttttaaacgc tctctaaatt gccaaactcc cttaggattc aaatattctt
    32101 gataggctgc ttgcccatct tcaaaaaaaa taatactcga tataaaccct cgatcatcca
    32161 tgatatggtg catatgtatt tgaccatttg gttcaaaata ctgtatatca ctgatgaagc
    32221 cttcaactcc atgttcaacc ttagcaaatt tcttcccatt tttttgaacg ataatcgtaa
    32281 agggactata aataaattca cagtcatcat cccactcaat atctctaatg cttaaaactt
    32341 gggtatggag attatgaaaa tcttgcataa catcaaaaac ggaataagta tccgtttcta
    32401 acacaccatg tctatataaa aaataacgta gatgaggctg gtaagctaat actaatagac
    32461 gagaatctat atcttgctct tgaaagagcc ggatctggtg aaaggtatca tcaaactcta
    32521 gacgaaaatg agaaaaatac catggagtga tatctgcatg ccatgttctt tctgacccat
    32581 accaagctgg aataaaataa tacataaaag tctcctaaat caaaggttta taggtctcat
    32641 ttagccttaa agccttgacc tcgtctctaa tcgtaaaaat catgcctcca aacatcataa
    32701 acaaacctgg aatcattgcc aatcgtaata acttttcatc aaacaaaaca aaaagcatgg
    32761 gaccacctgc cataaccaca ttaaagagac cacctatgac tgagaaacga aggaccaatc
    32821 gattaataaa tcgactagta tccgcacctg gataaatacc ataaatgtat tctccagatt
    32881 ttttcatacg gtctgcaatc tcttctccat tcatcgtaac aaaagcaaaa atgatactaa
    32941 ataaaaataa gaccgaaata taaacataga cccacaaagg ctttccaatc ataaattcct
    33001 ttgataaagc cgctaaccct gaatgattag ggaaaataaa tcccaacaag atgaacaaat
    33061 aagctggtac actaagaaaa ctcatcacat acatataagg catcccacct gcaggattca
    33121 acatgatttc gagataaaaa tagcgtttaa atcgattgtg taagccaatt ttattaacag
    33181 gaaccaaata gcgagctcga tacataaggg caagtaaata agaaaagaca agggttaata
    33241 aagcaagtaa cacaataatc cctgttggaa tgtgtactgt ctgaaatgtt tccaaaacat
    33301 cctgaggaat atttaaaacc atactggata ggagaatgac tatagaacct ccaatcccca
    33361 tactcgcatt taaatctgac aaccaaacaa gaaaaaatgt tcctgctatc agcaatattg
    33421 tattcattag aacaaccaat attgcagaat aggaggattg tactggcagt ctcaagctaa
    33481 ctgccaatga ttgaatgaca gctatcatca aggtcaggta cattttacgg cgatcttgta
    33541 tttctataga cgtagatgtt aaacccaacc gtttagaaaa agaaaacatc tgccataaaa
    33601 tcatagctga catccaaggg gacaatccaa cagaaaaaat tgacaaactt cttagatttc
    33661 cacctgttag ggcggctgag aaggctagat aggctgttga acctcctaaa aaatctttag
    33721 tatttaggtc aacaaaaggg agagtaatac gacttcccaa tacatagata aacagtagaa
    33781 ataaggtaaa tagtcctttt tttactgcta ttgacgaata aatcttagtc ataaaacact
    33841 cccctcacct tcattgtttg tgatatggta aataacaatt cttttatttc aacttttacc
    33901 atttctttgt tctgcatcaa aaaacaactt taatctgaaa caaatatctt tatattcctc
    33961 agtatctgtt aattgatggt attctaaagt ttgcttataa tcttttaaaa gattgacaaa
    34021 tcgaatacgc agaacggaga catccaaacc agccaagaca caatccgata ttttcttaga
    34081 aaacacttca acaatatctc ttgcccagga aagatcaaat tccgttctca tgatgcttcc
    34141 tgaacgtctt ctatacagat agagattatc gtttataaag acgattttag aggctaaaag
    34201 ataaaagcga tgcatagttg cttcatcatc aaagcggcga ccatttgaaa agtgaacttc
    34261 attgaataat tcttttttaa tcaacttaaa tgtcggcaat ataaaggccg agctattgaa
    34321 tttccaatct cctgcttgac ggttcataat ttcttgtata gctaattctt cgacgcaaaa
    34381 atcttgccct gttacataaa aataaaaatt cccgtcactt tcgtcataat tatagtaatt
    34441 ccctataaca acatctgcat ccttttcttg gacttgctga taaagagttt caatcatatt
    34501 ttcttttacg atatcatctg aatcaacaat cgtgatgtac tctcccttag ctacactaat
    34561 ccccatattt ttagcttgtg ctgccccccc ttattttctt gatgcaatac tcgcacacga
    34621 ttatcttgca tcataaaagc atcacaaatt tccccagaat tatccgtaga accgtcatca
    34681 actaaaataa tttctatatt ttgataggtt tgcttcagaa tatgctcgac acactccact
    34741 aaatattttc ccgtattgta tatcggtacc acaacactaa ttaattcact cattactcta
    34801 tctctatatt cttcattcta tccactaaat catctggtct ctccacagaa aaaataccgt
    34861 catagagtcc atcatccata cttttacgtg tgatatcaaa agcgaagatt ttcttgccac
    34921 tttcttgtgc ccttgtaact acattaaaaa cctctccacc tgtattaata tctaaataaa
    34981 ctatagaatc gtccaatagc caatcaattc tactatgtaa tacattttga tatactgtta
    35041 cattcgtata ctgtgataga gaggtcagct cctcagaaca atcacacggt gcagccaaat
    35101 gaaaatgcca atcaggtaac cgttgtacta aatactctaa atgttttata tctgcactcc
    35161 atgtcacaag catcacttgt tttttagact gattgcttct ttcaaaataa tttaaatcgg
    35221 aacgttgaaa agcaatctct gaccaatcca aatctctata aacccaccat aattcacgta
    35281 gtctagatat actatatgta ttccaaggtt tatcatgact agcatagtga acaattgtag
    35341 gtggattgtc atctagacgt tcacattctt gagcaaggtg ataaatatca acacccacca
    35401 tataattata tgttttatct aaggctagcc aattatcctc aaaataaata tttaaaatac
    35461 tctgatcccc aagatgaaca acttgatttt gctcggccgc taattccaat aaactattga
    35521 caatagagtg ttctttccat tttgcaacat ccattagtaa cataccagca ttaaatccag
    35581 attttcgtcc ttcataggca tagacatcat caacagcacc aattgaatat cctttgagat
    35641 ctatctcaaa caaagtagct agttccccag ttacaatgat atcggaatcc agatacaata
    35701 ccctatcaga ttcaaccact tctgtcgcaa aaaatctaaa gtaagaagca taatttatat
    35761 gaggtcctgt tttatagctt tcaaaaagtt ctttatcaat gtgtacactg cgaattgtag
    35821 aattcacaac ttccattttt ctccccaata atttaaacca ttcaggagct atatcactgt
    35881 tgagaatata aaaatcaaca tctctattgt gatacaatac agactttata gtcgtctcta
    35941 aaggaataag ataggcatta tctgccgcta atactattga ttttctcata ctgttctcta
    36001 cctcatgtaa gatctgattg ctgcaaccat ttttttcgga atggagcttg gatagatacc
    36061 ttcatatgaa atctcagaaa gattttcaga gcaagtattg tcgaaagcta tcattggttt
    36121 tttgtactta agcacaaact catatgcatc ttctaatttt cgatcatgat tcaaatccaa
    36181 atacaaatct gaagctatta ctatttgttc caataacatt ggtaaggaat ttggatatac
    36241 ggtaacatta ggaaaacgcg ttaaagctag tagttcattt gccatatttg tataagcaac
    36301 aatatgaaaa tgaacttctg gcaattgctc cgccaaataa tcgattttct cgacacacca
    36361 agaattcgtt aaattaacac attgtaactt aaatatttgt gatttactag gatacttcac
    36421 actctttgaa aaccattcat ttaaaataac agaccaatcc atcaaagagt attcccacca
    36481 aacttctctt agacgtccaa cagaaaattg attccaaggc ttatcctgag aaatatagtg
    36541 taaaattagt ggcagtggtt cgagcggaat atcaaaaatg aattgatgtt taaaggctgc
    36601 cgccccataa tcatatccta tttgaaaatt atattgatct tcaagggaac tatattgatc
    36661 tttaaacaac atattcaaaa ttgactggtc tccttcttcc acattctcat gttctttttc
    36721 tgttaagtca atcaattttt gtcgaatagt ttcagatccc cattttttgt tgttaatcaa
    36781 gagaacacca gcattgaagc cgactcctgc tccaaagcaa gaacgagctg ctgccaaata
    36841 attttcacct aagtctaatt caaacaaatc ggtcaaatca ccagtcacaa tcaaatcact
    36901 atctagatag agaactttat cttctgttac aaaatctgga ataaaatagc gtgcaaatgt
    36961 catatgattg atatgaggta atttattaga ccaattcatt tgaaactgtg agccaattaa
    37021 cttgcagtca atcaagtcgc cccccatctc ttgtaaatat attcttattt gactaaacca
    37081 ttcctgagga atgtcctgat ttagcagata aattttcaaa tgactattgt gtctacagag
    37141 tgacttcatc gccgtttcga tttgtcgaat ataagcgtaa tcacctgcaa atgctacagc
    37201 gcgtttggta tttctcattt taaatcctta tcatttattt taaatagtct agtttaatat
    37261 tcgtgcaaca atctgactgt tataggtttc atcatcaata aattcaatat cttgatcaaa
    37321 attatactct gcagtatgtt tatgagaaaa tttaacctta gttttagctc ccattttcat
    37381 ccattcatac tctgagtcaa tatggcctac atccaaaact tgatagccca tctggcatag
    37441 attataactc agaacttttg ctgtaggacc cagcatacat aaaatcaagc gaccaccagc
    37501 atacttttca atttcttgtt caatttcatg aactctagaa aaggcactat gagaaggaca
    37561 gataattcgc ttaatagaat ttgcctcatc gaataaatca tttccgacac ctgaacgaga
    37621 agtcgcacct tcgactatca gtaagtcacg gttttcccaa atgcttttca atttttcaaa
    37681 ttgagcttta gcttgactct tgtcttcaaa atcgatataa gggcgagata caaaggttga
    37741 gccataccat gaatcactgc ataactctct gtaaaaatcc atataatgat ccatgtgatc
    37801 tttccaaaat ggaatcgccc acgatgtaaa cctaaaacga tctgtaaaag catcaggaag
    37861 gcacactact aaatcttctc gactttcttg gccgataatg tccctcatga ttgaaaccaa
    37921 ctcttcatca taatcctggt agggaattga atgccctgca agcatattga tttccccatc
    37981 tccaaaacga actaaagaag agttgtgttc aataatataa tccaaggttt catctatccc
    38041 tttcacctgg attatatcaa gcggtttttc tagcatatcc ttagttatca atttttgcaa
    38101 atcagccaac attcgttcag gatgttcact tgaatacaac ctttggccat tattcccatt
    38161 ttgagattta taaaaggcta gtataggttt agatagatga gccatttctg caacgatatc
    38221 ggatgttgaa gtcagtaggt tgatatctaa ataagcatcc atcttctcct tcaactcgtc
    38281 tagcttatct ctagaaattg ccggatagag ctgaatatta ggataacgat tagacaaatc
    38341 atataatttt ggccccatag ctgtccaagc agcaacttga aaaacaacat ttggcaactg
    38401 tccagccaag taatccaatt gttcgatatc ctgagaagcc gtaaacgtta aacaagttaa
    38461 acttggaagt tgtcgaaaac aggtaagatg tccgtttttc ttaaaatctt taatcgtatc
    38521 aatcataaag gaaactttcc cattttcgaa aacgatttgt cctaactctc cgtgctgagt
    38581 cgattgaaaa gctagtagcg ttttttcttg ttcttgcaaa gattttaaaa agttctcatc
    38641 tgcactacca tgattgatat ccaaatatag atttgttgac tttttcagct tatctaatac
    38701 aggaggaaca atttgtggat gcaatctcac attatcatac acagctaatt ttatcagctt
    38761 atcacccata tccgtccaag cagcaatatg aaataccaca tctggtaaag ctgtgactaa
    38821 ctcttctatt ccttctaaat cttgggaatt tgtcaaagtt aaacaagaaa attccttatc
    38881 taaagacgat gtcagttcaa actcccctat atgatgttgt aaaattttag tccattccaa
    38941 atcatgaaat tcccaccata aatcacgata acgattggct atcaaggtgg tccagggttt
    39001 tctgtaagac acaaaatgaa taatactagg aggtactaac tcattaaaat aattttccca
    39061 tttattataa aaagcagtta catcatgacc cacttgaagg ttaaattctt tatccagctc
    39121 taaccaatca tcttgtaaga cctgattaaa aatcgtttga tcaccattaa aatgctcgaa
    39181 acggccttct tcaacttcct tcattgtaac aatgctctgt tcaattagtc gttcttttaa
    39241 tttctcttga cgccattttt tattgttgat taataaaaca cctgcattaa atgtaattcc
    39301 atctgtatct ttaactgctg cgagtgattt ttcttctaaa caaatactaa ataatttctc
    39361 taaagaagta tttacaatca aatcactgtc taaatataaa accttatctt cttggatata
    39421 atctgcaata aaatatctag tataggtaat gctactaatg tgatcttgct tttcccaatc
    39481 ttgaaacaca gtttgttcag gtagcttcac atcgataatc tcactaccta acatgcgagc
    39541 tatttttcgt ggtttgcgaa accaatctgg cataatatct tgatttaaaa tataaatctt
    39601 aacatctcga ttgtggtata aaatagattt tatggttgtt tctaactgcc tgatgtaatt
    39661 acgatcacca gctaatacaa ttgttttaat catcttgttc tcttattcaa ctcccaaatg
    39721 gtaaattgca tctaccaata attttttagt aaaataacct tcttttagca aataactaaa
    39781 ggtttttatc cgattcgtca tttcttgata ttcttgtaga ttcattttat caactatcgc
    39841 atgaacttct tctagactat tcgccacaaa gcctaagcct tgatctacta taaatttagc
    39901 agttgacaag ctacttggta caatgactgg gatgcccgct gtcagatagg tactcacctt
    39961 atgagatata tttaaggtat aatattggtt gctttctcca tcgttttgat aagttcccca
    40021 gacaaggcca aatccaccct ttgataattc tagcaacaat tcctcatctt ttttccatcc
    40081 ttcgatgctg agatttctag cactagaact agcttcccct ttatttgaaa atactctcaa
    40141 aggcgtatct tgagaccaat tttgtaagtc tggaaaacgc tctaaacttc cagcaaaaaa
    40201 aagttctttt ttaaaagcag gggtgtataa ggataaatca tgaggatgat cccacatccc
    40261 ttgaacaaga atcttcttag tcgtcaatcc ttcttccatc aggcgtgttt tcattctctc
    40321 tgacggcact atcaaaacat ctgatagatt atacatgtac atatagtctt tcatgagata
    40381 atagttacta tcaaacatga ggggaacaac atcatggata aagcaaataa ttttcacctg
    40441 catatccttc aacttatcaa acaagagacg atcaaattca aagccattcc aggttggaga
    40501 ctgaaagact aaaatatccc caatagaaat actggccata ataccatcca gacgcttatt
    40561 catttcagaa ggactatctg aagcaatgtt gtaaaaataa ataccaacct ctctaaatcc
    40621 cagttgacta gctatctttt gaacagcatt ttgagctaag ataaccgtac tatcaccagc
    40681 catgccgtat aaatttgtta aatgtagttt catattacgc tatctcattt tttattacta
    40741 tctacggaag taaagacaat ttttccatca ttcttctata aatctctgtg aactgcatat
    40801 tttgttcttc taattttgct atcactcttt gtaatctatt tttataaatc aaaatatgat
    40861 tggtcaagtc atagtctgaa cttgctaaaa tagctatctt ttcttcccta gccccgattt
    40921 catcatacat acgcttttca ctccatgtat tcgataaagt atcagataaa ccaacacggt
    40981 accagtaaac acaacgattc aaatagacta tcctcgaagc tcttagaagt accttccatg
    41041 tccagtaagt atcctctgca atttttccta taggaaatgg taaatcttgt agtaactctc
    41101 tcttgaataa cttcaagaca gctacagtcc agttcccatt tctgacttct tcgacacctt
    41161 ccctatccat gattgcttta ccttctatca cttccagaga atcatctgga tccgtaacat
    41221 aagtcatata cacatagcgt gtttcatcat aagaattata acgcccgata ctaatatctg
    41281 cgttttcctt tttcaaagca ccatataatc ggtctaaagc atcatgttcc aaccaatcat
    41341 cagagtctac aaaagtaatg tacgcccccc ccgaacattc aatacctagg ttacgagctg
    41401 atgaaagacc gccgtttgct ttctcaaaat atttgaaacg agaatctttc tctacaaatt
    41461 cttcacatat tttggatgaa tgatctggag agccatcatt aaccatgata cattcaaaat
    41521 tcggataagt ttgtttttga atactatcca aacactgtcg caaataattc tcaacgttgt
    41581 agattgggac tacaatacta attagttcat tttccatata ctaactttcc tagacttgat
    41641 ttattctatt tccctcttaa tctcttctct ttacaacaag atttccatta ttataaacta
    41701 cactgtttga tggaatatca ttgcgtatga gacaacctgc tccaataatg gtattatccc
    41761 caatcgtcac tccttttaaa atcgtgacat tacttcctat ccagcagtct ctgccaactc
    41821 taatcggcgc tgtagtccac tgccactttt caatcttttc agcagtataa atatggtcgt
    41881 gatcataaaa acgaacaccc tctcccatca tggtaccagc tccgatttca attctttcca
    41941 tacagttaaa actacaagag ttgttgataa aaacaccatc atgcagtatt aacttaccag
    42001 aagagacatg aaaattttca aaatttctgc agatgacatt tgctcctaca atgaagtgag
    42061 ccttatcatc gattttaaag acattccaag tcccatcttg gatgattttt tcttgatgat
    42121 tggtgcctac tctgacttca ttcagatagt ctctcactct agaaaccaat ttgtctggtg
    42181 tacttgatag aaaaacttcc tgcccctgat ttccatggac tgtattgtca aaagcaaaga
    42241 cagattttcc agcctgtaca aacttggaga caatagcatc tacttcttga aagtgattga
    42301 tatctagtaa aaagtcacag gtatcgacta gaaagtttag ctgttcttca tttgtaatcg
    42361 ttcggagacg gacattatag ttcgtttcta agctacggat tttctcggaa aattgaacag
    42421 gtgctgcaat ataaaaacag atatttggca aggattcaag gagataatcc aactcttcaa
    42481 tctgatcact aacagtcaaa atcagagcat ctcctactaa atgatttttc ttcatttgct
    42541 tatttctctc aatttctcaa tcattgcttg aacttggtca acagcatata cctcctgacc
    42601 tgcttcatag gttttggtat tttcaaagga caaaatagtt tttccaagtc ttgcaaattg
    42661 attgataatt tcctctgttt tttcaccatg attaatatct aaaagtactt gactggtttc
    42721 taccaattca ttatcgacat ctaccaaata gtgaattccg ttaaatatag tcacgtttgg
    42781 ataaattgtc atctgagcca atcgatcact aactattact ctagctgcta tcttaaactg
    42841 aatatcaggc aaggattgaa ccaatgtctc aatttgttca atatggtctg aggcagtata
    42901 gattagacaa gtgaaaggtt cctttattgg atagatgtga gatctttgta atggatgtaa
    42961 atgatggttt tgtcccaatt ctgtccattc aagcccatga tagtaccacc aaacttcacg
    43021 ataggtttgg gccgccaaat ctttccacgg tttccgatga gaaagatagt gaataatagc
    43081 aggataatcc tgaccctcag gcaattgata atcagcaaac tgtttatgaa tgacaatatg
    43141 attataatca aagtccaatt ccaaccattt atgttcaaaa agcatattca agatgctctg
    43201 atctgcctga tccaccttat catgccattc attggttaca tcaattaatt tttgggtcat
    43261 attctctttt ttccaaaaag cattgtttac caagagaaca ccggcattaa agatttcttg
    43321 accaaaataa gctctgcccc caaaatctct aacagcagcc aaaggataat cttgtaagtc
    43381 tgtagcaaac aaatcatcaa gatttttcgt tacaagtaaa tcacagtcca agtagagggc
    43441 cttatcttct tgcacgaaat cagctatgaa atagcgtaaa aaaactgtgt aactaatatc
    43501 cgttttataa catgaaattt gctcagaagt tacccgacaa ttaataattt ctgagtcaaa
    43561 cttctctaag cgcttattta attgcttaat ccattcattt ggaaaatcgc tatgaatcag
    43621 ataaaaacga atcgaacgat tatgataaca aatagacttg attgtcgtta aaacttggtc
    43681 tacatagcca tagtttgctg ctaggacaat ggctttcttt tcacttgatt cttgtaccgt
    43741 taactgattt aaaagtcttt ttttcatttc aaactcttta tatattgctg tgtcagataa
    43801 accactagct tgaccgttgg cgagactgac ttccaacatc tgacgataaa ctgccaagtg
    43861 tttctctaga ggatatccca tattagctag tagcgtaata cgttcagaca tagcatcaac
    43921 taaggcgtgc atccactttt ctgtccaaac tcttgataga ctaccttttc taatccgata
    43981 agcataaaga cctttattta aataaattac cttttccgat aataaatata ccttttgatt
    44041 gaggtaacca tcttctccta atttacccat gtcaaagcgc aactgctcaa acaatcttgc
    44101 cttatagagt ttaccacaag cagatatcaa agcaaaactc ttcatttctt gagtttcata
    44161 acaagttctc aaagatggaa acattgtcat ataccttatc ataataggag tctcctgata
    44221 tatgaaagta gaacattcct tcactttcgt tgaaagaata gtaattccca actgcaatat
    44281 cagcttgata ttctgttatt tttttatata gggtttctac ataatctaac tcaatccaat
    44341 catctgaatc cacaaaggtc acataatttc cggacatatt attcagaccg gtgtttcgtg
    44401 cggcagaaat accagcattt tcttgttcta tatagagaat tcggtgatcc atttctgaaa
    44461 attctttaca aatttcacct gaagcatccg tagaaccatc attaacgaca acaatctcaa
    44521 tatttttata tgtttgagaa ataatactat ctagacattt cctcagatag ttttctacat
    44581 tgtatactgg tacaatgacc gtaattttat catccactag caattttctc cttgatttat
    44641 gtgcgcgagt tagtttagcc taactttaca ggttgtctta ctcttcttca tcacgtttac
    44701 ggcgtttcgc aaccaatcca atacctgtaa cagctgctag aactccaagt aacacagatc
    44761 caattgacga ctcagtacct gtattaggca attctttttg ggatttacct gtcgatccag
    44821 aagcatttcc aacttgtgag ttcgaatggt ttgctgaatt tgaaactgat gtacttgctg
    44881 aggctgacgc actcgttgat gctgactcag acgcactggt tgatgccgat tcagacgctg
    44941 aggtgcttgc tgatgctgag gcactggttg acgctgaagc tgaggcgcta gtacttgctg
    45001 aagccgaggc actggttgat gctgaggctg aggcgctagt acttgctgaa gctgaggcac
    45061 ttgtcgatgc tgaggccgaa gcactggtac ttgctgaagc cgaagcactc gttgatgctg
    45121 aggctgaagc actggttgac gctgaagctg aggcactcgt tgaggctgaa gccgaagcac
    45181 tcgttgatgc ggaagctgac gcactggtac ttgctgaagc tgaggcgctt gtgcttgctg
    45241 aggccgaggc acttgttgag gccgattcag aagctgaggt actcgttgat gcggattcag
    45301 atgctgaggt gcttgctgag gccgaggcgc tggttgatgc agaagctgag gcactggttg
    45361 acgctgaagc tgaggcactg gttgaggccg attcagaagc tgaggtactg gtgcttgctg
    45421 aagctgaggc actcgttgat gccgattcag acgctgaggt gcttgctgaa gctgatgcac
    45481 ttgttgatgc tgaggctgag gcgctggttg atgccgattc agacgctgag atacttgctg
    45541 aggctgaggc gcttgtactt gctgaagtcg acgcactggt tgaggccgat tcagatgctg
    45601 acgtacttgc acttgttgac gccgatgtgc ttgcacttgt cgatgctgac gtgcttgccg
    45661 atgtacttgt gcttgttgat gctgacgtgc ttgctgaagc cgaagcactg gtgcttgctg
    45721 aagccgatgc acttgtactt gctgaggttg atgccgattc agacgcactc gttgatgcgg
    45781 aagctgacgc actggttgac gctgaggctg acgcactggt acttgctgaa gctgaggcgc
    45841 tcgttgatgc cgattcagac gctgaggtgc t
//
LOCUS       DAVAZT010000011        45402 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVAZT010000011 DAVAZT010000000
VERSION     DAVAZT010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45402
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.011"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            434..886
                     /locus_tag="VQT45_000550"
     CDS             434..886
                     /locus_tag="VQT45_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2358916.1"
                     /translation="MIITKISHLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVQLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            905..2242
                     /locus_tag="VQT45_000551"
     CDS             905..2242
                     /locus_tag="VQT45_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET2358917.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2321..3205
                     /locus_tag="VQT45_000552"
     CDS             2321..3205
                     /locus_tag="VQT45_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2358918.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3205..4038
                     /locus_tag="VQT45_000553"
     CDS             3205..4038
                     /locus_tag="VQT45_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2358919.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4056..6149
                     /gene="nanB"
                     /locus_tag="VQT45_000554"
     CDS             4056..6149
                     /gene="nanB"
                     /locus_tag="VQT45_000554"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HET2358920.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKRSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNREESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6161..7264
                     /locus_tag="VQT45_000555"
     CDS             6161..7264
                     /locus_tag="VQT45_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET2358921.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            7438..8136
                     /locus_tag="VQT45_000556"
     CDS             7438..8136
                     /locus_tag="VQT45_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET2358922.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8155..9672
                     /locus_tag="VQT45_000557"
     CDS             8155..9672
                     /locus_tag="VQT45_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET2358923.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFLGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            9797..11125
                     /locus_tag="VQT45_000558"
     CDS             9797..11125
                     /locus_tag="VQT45_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2358924.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11377..12243
                     /locus_tag="VQT45_000559"
     CDS             11377..12243
                     /locus_tag="VQT45_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2358925.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            12259..13098
                     /locus_tag="VQT45_000560"
     CDS             12259..13098
                     /locus_tag="VQT45_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2358926.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13371..13823
                     /locus_tag="VQT45_000561"
     CDS             13371..13823
                     /locus_tag="VQT45_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2358927.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEATDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPTGYAGMEEKVRKYLFKILID"
     gene            13920..14264
                     /locus_tag="VQT45_000562"
     CDS             13920..14264
                     /locus_tag="VQT45_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2358928.1"
                     /translation="MVSSKHAARASFLDGQEITVDEMSWIINGIVNALIGRYIKLGTY
                     AAKYGIGIARSILSRAAATAAARVGLLTKISGWILRVAVNVADVYGNFANNIAAAWDA
                     YDKIPNNGRINF"
     gene            14548..15192
                     /locus_tag="VQT45_000563"
     CDS             14548..15192
                     /locus_tag="VQT45_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET2358929.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15361..16278
                     /locus_tag="VQT45_000564"
     CDS             15361..16278
                     /locus_tag="VQT45_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HET2358930.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTATHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKESFL"
     gene            16296..17180
                     /locus_tag="VQT45_000565"
     CDS             16296..17180
                     /locus_tag="VQT45_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2358931.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17196..18047)
                     /locus_tag="VQT45_000566"
     CDS             complement(17196..18047)
                     /locus_tag="VQT45_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET2358932.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANRVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18247..20304
                     /gene="pbp2b"
                     /locus_tag="VQT45_000567"
     CDS             18247..20304
                     /gene="pbp2b"
                     /locus_tag="VQT45_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HET2358933.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTKRQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEINKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            20315..20911
                     /gene="recR"
                     /locus_tag="VQT45_000568"
     CDS             20315..20911
                     /gene="recR"
                     /locus_tag="VQT45_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HET2358934.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21087..22130
                     /locus_tag="VQT45_000569"
     CDS             21087..22130
                     /locus_tag="VQT45_000569"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HET2358935.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            22214..23587
                     /locus_tag="VQT45_000570"
     CDS             22214..23587
                     /locus_tag="VQT45_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HET2358936.1"
                     /translation="MKLTIHEVAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGVRDGHDFIERAFENGAAATLSEKEVANHPYILVDDVLTAFQQLAAYYLEKTAVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQVLDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGVQSVQLHNQMILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVE
                     SLENEDK"
     gene            23574..24185
                     /locus_tag="VQT45_000571"
     CDS             23574..24185
                     /locus_tag="VQT45_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2358937.1"
                     /translation="MKTSDFVKYLQRMIAITDTGLTFTKDPFDRERYEDLRDLLSEML
                     NQASDLDSEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDPLPNLSEKRITKEQIEILWQVYQGQREQYLD"
     gene            24276..24980
                     /locus_tag="VQT45_000572"
     CDS             24276..24980
                     /locus_tag="VQT45_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HET2358938.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25199..26572
                     /gene="ftsA"
                     /locus_tag="VQT45_000573"
     CDS             25199..26572
                     /gene="ftsA"
                     /locus_tag="VQT45_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HET2358939.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENIIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVESVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26589..27848
                     /gene="ftsZ"
                     /locus_tag="VQT45_000574"
     CDS             26589..27848
                     /gene="ftsZ"
                     /locus_tag="VQT45_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HET2358940.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            27853..28524
                     /locus_tag="VQT45_000575"
     CDS             27853..28524
                     /locus_tag="VQT45_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HET2358941.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28534..29073
                     /locus_tag="VQT45_000576"
     CDS             28534..29073
                     /locus_tag="VQT45_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HET2358942.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            29073..29336
                     /locus_tag="VQT45_000577"
     CDS             29073..29336
                     /locus_tag="VQT45_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HET2358943.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            29333..30017
                     /locus_tag="VQT45_000578"
                     /pseudo
     CDS             29333..30017
                     /locus_tag="VQT45_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
     gene            30026..30814
                     /gene="divIVA"
                     /locus_tag="VQT45_000579"
     CDS             30026..30814
                     /gene="divIVA"
                     /locus_tag="VQT45_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HET2358944.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            31162..33954
                     /locus_tag="VQT45_000580"
     CDS             31162..33954
                     /locus_tag="VQT45_000580"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HET2358945.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYANFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEEPAPEAALSFEDVVFTVERAAGEVCDRCRRIDPTTAERSYHAVICDHCASI
                     VEENFADAVAEGFEEK"
     gene            34364..34726
                     /locus_tag="VQT45_000581"
     CDS             34364..34726
                     /locus_tag="VQT45_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2358946.1"
                     /translation="MKSSGIVGLVGGILLLICPFVLLGTAVNTAATTLNGGATAGAFS
                     GVALLLNALKIANLVLGIIAIVYYKGDKHVGAAPSVLMIVSGEVSLIPFLGWVGGILA
                     IIGGSLFLATLKKFKSEE"
     gene            35261..35953
                     /locus_tag="VQT45_000582"
     CDS             35261..35953
                     /locus_tag="VQT45_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HET2358947.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            36006..38417
                     /locus_tag="VQT45_000583"
     CDS             36006..38417
                     /locus_tag="VQT45_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET2358948.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     RKAFASFPDDLLIQCFTKEGLETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYSGNLFSY
                     KGQEYIEAARAILNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            38667..39368
                     /locus_tag="VQT45_000584"
     CDS             38667..39368
                     /locus_tag="VQT45_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2358949.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIQMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            39370..42070
                     /locus_tag="VQT45_000585"
                     /pseudo
     CDS             39370..42070
                     /locus_tag="VQT45_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
     gene            complement(42166..42657)
                     /gene="tpx"
                     /locus_tag="VQT45_000586"
     CDS             complement(42166..42657)
                     /gene="tpx"
                     /locus_tag="VQT45_000586"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HET2358950.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(42780..43709)
                     /gene="psaA"
                     /locus_tag="VQT45_000587"
     CDS             complement(42780..43709)
                     /gene="psaA"
                     /locus_tag="VQT45_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HET2358951.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(43741..44589)
                     /locus_tag="VQT45_000588"
     CDS             complement(43741..44589)
                     /locus_tag="VQT45_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET2358952.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(44586..45308)
                     /locus_tag="VQT45_000589"
     CDS             complement(44586..45308)
                     /locus_tag="VQT45_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET2358953.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
BASE COUNT        13818 a         8141 c         9963 g        13480 t
ORIGIN      
        1 ttagaaaaac gaagtgagca gcttataaat tcaagtcccc aaatagattc atactagtat
       61 cttttgcaaa aaataaaggg cgacttcctt catgaatatc aatttcatct ataaggaagg
      121 tagctaattg aactaactta tttattctgt ttgtcgctag aaaaatcaga cctccttgtg
      181 aagattgagg agatactgaa tgaaaatcaa agaagaaact agcaagctag tagcagattg
      241 cccaaaacac cgccttgagg ttgtagataa gactgaccta tataatccaa ggtgaagcga
      301 ctgtggtttg aagagatttt caaagagtat aggctagaga gtagtgtttt tatgtccttc
      361 tagtagaaaa tgctagacag aagaatgggg aacttggata ggaaaaatag attgagaaag
      421 gaggttagaa gagatgatta ttacaaaaat tagccattta ggaacttatg tgggagtaaa
      481 tccacatttt gcaacattaa tagattttct agaaaaaaca ggactagaaa atttaacaga
      541 aggttcgatt gctatcgatg gtaatcgatt gtttgggaat tgctttactt atctagcaga
      601 tggtcaagca ggggctttct ttgaaacaca ccaaaaatat ttggatattc atttagtttt
      661 ggaaaacgaa gaagccatgg ctgttacatc gccggaaaat gtaagcgtta cccaagaata
      721 tgatgaagag aaagatattg aattatacac agggaaagtg gaacagttgg ttcagttgag
      781 agctggcgaa tgcctcatca cttttccaga agatttacat caacccaagg ttcgtataaa
      841 tgatgaacct gtgaaaaaag ttgtctttaa agttgcgatt tcttaatgta gaaagagaag
      901 aacgatgaaa aaaatgagaa agtttttatg tctagctgga attgcgctag cggctgttgc
      961 cttggtagct tgttcaggaa aaaaagaagc tacaactagt actgaaccac caacagaatt
     1021 atctggtgag attacaatgt ggcactcctt tactcaagga ccccgtttag aaagtattca
     1081 aaaatcagca gatgctttca tgcaaaagca tccaaaaacg aaaatcaaga ttgaaacatt
     1141 ttcttggaat gacttctata ctaaatggac tacaggttta gcaaatggaa atgtgccaga
     1201 tatcagtaca gctcttccta accaagtaat ggaaatggtc aactcagatg ctttggttcc
     1261 gctaaatgat tctatcaagc gtattggaca agataaattt aacgaaactg ccttaaatga
     1321 agcaaaaatc ggagatgatt actactctgt tcctctttat tcacatgcac aagtcatgtg
     1381 ggttagaaca gatttgttaa aagaacataa tattgaggtt cctaaaactt gggatcaact
     1441 ctatgaagct tctaaaaaat tgaaagaagc tggagtttat ggcttgtctg ttccgtttgg
     1501 aacaaatgac ttaatggcaa cacgtttctt gaacttctac gtacgtagtg gtggaggaag
     1561 cctcttaaca aaagatctta aagcagactt gacaagccaa cttgctcaag atggtattaa
     1621 atactgggtt aaattgtata aagaaatctc acctcaagat tctttgaact ttaatgtcct
     1681 tcaacaagct accttgttct atcaaggaaa aacagcattt gactttaact ctggcttcca
     1741 tatcggagga attaatgcca acagtcctca attgattgat tcgattgatg cttatcctat
     1801 tccaaaaatc aaagagtctg ataaagacca aggaattgaa acctcaaaca ttccaatggt
     1861 tgtttggaaa aattcaaaac atccagaagt tgctaaagca ttcttagaag cactttataa
     1921 tgaagaagac tacgttaaat tccttgattc aactccagta ggtatgttgc caactattaa
     1981 ggggattagc gattctgcag cctataaaga aaatgaaact cgtaagaagt ttaaacatgc
     2041 tgaagaagta attactgaag ctgttaaaaa aggtactgct attggttatg aaaatggacc
     2101 aagtgtacaa gctggtatgt tgactaacca acacattatt gaacaaatgt tccaagatat
     2161 cattacaaat ggaacagatc ctatgaaagc agcaaaagaa gcagaaaaac aattaaacga
     2221 tttatttgag gctgttcagt agatgtaaaa gactagaaaa taggtgggct agtgagctga
     2281 aaagctctag cccaatcttg taaaagaagg gagaaggaga atggttaaag aacgtaattt
     2341 aactcgctgg atatttgttt tgccagctat gattatcgta ggattactct ttgtttatcc
     2401 gtttttctcg agtatttttt atagctttac caataagcat ttgattatgc ctaattataa
     2461 atttgttggt ttggctaact ataaagctgt gctatcagat cccaacttct ttaatgcgtt
     2521 ctttaattca attaagtgga ccgttttctc attagttggt caagttttag tagggtttgt
     2581 attggcttta gctcttcaca gagtacgcca cttcaagaaa ttatatagga ccttattgat
     2641 tgttccttgg gcatttccta ccatcgttat tgccttttct tggcagtgga ttctaaacgg
     2701 ggtttatggc tacttaccta atctaatcgt aaaattaggt ttaatggaac atacacctgc
     2761 atttttgaca gatagtacat gggcattcct atgtttggtg tttatcaaca tttggtttgg
     2821 agcaccaatg attatggtta atgtgctttc agctttgcaa acagtaccag aagaacaatt
     2881 tgaggctgct aagatagatg gtgcttcaag ttggcaggtg ttcaagttta tcgtctttcc
     2941 acatattaaa gtggttgtag gacttctagt tgttttgaga actgtatgga tctttaataa
     3001 ctttgacatt atctacctca ttactggtgg tggaccagcc aatgctacaa cgacgcttcc
     3061 aatttttgct tacaacctgg gctggggaac taaattgttg ggtcgtgctt cagcagttac
     3121 agtattgctc tttatcttct tggtggcgat ttgctttatc tactttgcta tcatcagtaa
     3181 gtgggaaaag gagggtagaa aataatgaag aagaaatcca gtatttattt agatattctc
     3241 tcacatgtac ttttagttgg tgcgaccatc gttgcaattt tcccattggt atggattatc
     3301 atatcttctg tcaaagggaa aggggaatta actcagtatc caacacgatt ttggcctgaa
     3361 cagtttacat tagattattt cactcatgtt atcaacgatt tgcacttcat tgataacatt
     3421 cgaaacagtt taatcattgc cttggctaca accctcattg cgattattat ttctgctatg
     3481 gcagcctatg gtattgttcg attctttcct aaattgggag caatcatgtc gagactactc
     3541 gtcattacct acattttccc accaattttg ttagcaattc cctattcaat tgccattgct
     3601 aaagttgggt taacaaatag tttatttggc ttgatgatgg tttatctatc ttttagtgtt
     3661 ccatatgcag tttggctctt agttggattt ttccaaacag ttccaattgg aattgaagaa
     3721 gcggctagaa ttgatggtgc aaataaattt gttacgtttt ataaagttgt gctaccgatt
     3781 gtagcaccag gtattgtagc aacagctatt tatacattta tcaatgcttg gaatgaattc
     3841 ctgtatgcct tgattttgat taacaataca ggaaagatga cagtagcagt agcccttcgt
     3901 tcacttaatg gttcagaaat actagactgg ggagatatga tggcagcgtc tgttattgta
     3961 gttcttccat caattatttt cttctctatc atccaaaata agattgcaag tggattatca
     4021 gaaggatctg tgaagtagac gaaagaagga aaaaaatgaa taaaagaggt ctttattcaa
     4081 aactaggaat ttctgttgta ggcattagtc ttttaatggg agtccccact ttgattcatg
     4141 cgaatgaatt aaactatggt caactgtcca tatctcctat ttttcaagga ggctcatatc
     4201 aactgaacaa taagagtata gatatcagcc ctttgttatt agataaattg tctggagaga
     4261 gtcagacagt agtaatgaaa tttaaagcag atgaaccaaa ctctcttcaa gctttgtttg
     4321 gcctatctaa tagtaaagca ggctttaaaa ataattactt ttcaattttc atgagagatt
     4381 ctggtgagat aggtgtagaa ataagagacg cccaaaaggg aataaattat ttattttcca
     4441 gaccagcttc attatgggga aaacataaag gacaggcagt tgaaaataca ctagtatttg
     4501 tatctgattc taaagataaa acatacacaa tgtatgttaa tggaatagaa gtgttctctg
     4561 aaacagttga tacatttttg ccaatttcaa atataaatgg tatagataag gcaacactag
     4621 gagctgttaa tcgtgaaggc aaggaacatt acctcgcaaa aagaagtatt gatgaaatca
     4681 gtctatttaa caaagcaatt agtgatcagg aagtttcaaa tattcccttg tcaaatccat
     4741 ttcagttaat tttccaatca ggagattcta ctcaagctaa ctattttaga ataccgacac
     4801 tatatacatt aagtagtgga agagttctat caagtattga tgcacgttat ggtgggactc
     4861 atgattctaa aagtaagatt aatattgcca cttcttatag tgatgataat gggaaaacgt
     4921 ggagtgagcc aatttttgct atgaagttta atgactatga ggagcagtta gtttactggc
     4981 cacgagataa taaattaaag aatagtcaaa ttagtggaag tgcttcattc atagattcat
     5041 ccattgttga agataaaaaa tctgggaaaa cgatattact agctgatgtt atgcctgcgg
     5101 gtattggaaa taataatgca aataaagccg actcaggttt taaagaaata aatggtcatt
     5161 attatttaaa actaaagaag aatggagata acgatttccg ttatacagtt agagaaaatg
     5221 gtgtcgttta tgatgaaaca actaataaac ctacaaatta tactataaat gataagtatg
     5281 aagttttgga gggaggaaag tctttaacag tcgaacaata ttcggttgat tttgatagtg
     5341 gctctttaag agaaaggcat aatggaaaac aggttcctat gaatgttttc tacaaagatt
     5401 cgttatttaa agtgactcct actaattata tagcaatgac aactagtcag aatagagaag
     5461 agagttggga acaatttaag ttgttgcctc cgttcttagg agaaaaacat aatggaactt
     5521 acttgtgtcc tggacaaggt ttagcattaa aatcaagtaa cagattgatt tttgcaacat
     5581 atactagtgg agaactaacc tatctcattt ctgatgatag tggtcaaaca tggaagaaat
     5641 cctcagcttc aattccgttt aaaaatgcaa cagcagaagc acaaatggtt gaactgagag
     5701 atggtgtgat tagaacattc tttagaacca ctacaggtaa gatagcttat atgactagta
     5761 gagattctgg agaaacatgg tcggaagttt cgtatattga tggaatccaa caaacttcat
     5821 atggcacaca agtatctgca attaaatact ctcaattaat tgatggaaaa gaagcagtca
     5881 ttttgagtac accaaattct agaagtggcc gtaagggagg tcaattagtt gtcggtttag
     5941 tcaataaaga agatgatagt attgattgga aataccacta tgatattgat ttgccttcgt
     6001 atggttatgc ctattctgcg attacagaat tgccaaatca tcacataggt gtactgtttg
     6061 aaaaatatga ttcgtggtcg agaaatgaat tgcatttaag caatgtagtt cagtatatag
     6121 atttggaaat taatgattta acaaaataaa ggagaaaaac atggttaaat acggtgttgt
     6181 tggagcaggg tattttggag ctgaattggc tcgctacatg caaaagaatg atggagcaga
     6241 gattactctt ctctatgatc cagataatgc agaggcgatt gcagaagaat tgggagcaaa
     6301 agtagcaagt tccttagatg agttggtttc tagcgatgaa gtagattgtg ttatcgtcgc
     6361 aactccaaat aatcttcata aggaaccggt tattaaggct gcacagcatg gtaaaaatgt
     6421 tttctgtgaa aaaccaattg cgctttctta tcaagattgt cgcgagatgg tagatgcgtg
     6481 taaagaaaac aatgtaacct ttatggcagg acatattatg aatttcttta atggtgttca
     6541 tcatgcaaaa gaactcatta atcaaggagt tatcggagac gttctatatt gtcatacagc
     6601 tcgtaatggt tgggaagaac aacaaccgtc agtgtcatgg aaaaaaattc gtgaaaaatc
     6661 aggtggtcac ttgtatcacc acatccatga attggattgc gttcaattcc ttatgggggg
     6721 catgcctgaa actgtaacca tgacaggtgg aaatgtggcc catgaaggtg aacatttcgg
     6781 tgatgaagat gatatgattt ttgtcaatat ggaattttct aataagcgtt ttgccttgtt
     6841 agaatggggt tcagcttatc gttggggtga acattatgtc ttaatccaag gaagcaaagg
     6901 tgccatccgc ttagacttat tcaactgtaa aggaactctt aagctagatg ggcaagaaag
     6961 ctatttcttg attcacgaat cgcaagaaga agatgatgat cggactcgta tctatcatag
     7021 tacagagatg gatggagcaa ttgcttatgg taaaccaggt aaacgtactc cattatggct
     7081 atcatctgtc attgataaag aaatgcgcta tctgcatgag attatggaag gagctccagt
     7141 atcagaagaa tttgcaaaac ttttgacagg tgaagctgcc ctagaagcaa ttgctactgc
     7201 agatgcttgt acccagtcta tgtttgaaga tcgcaaagta aaattgtcag aaattgtaaa
     7261 ataaattttg gtattctcct atttataggt cgacttgctc ctctgaaagt acttttagag
     7321 gagctgtttg actttgctag tttttgaaac tgaaatctat tatactacaa actattgaaa
     7381 gcgttttaat tttaaggtat aataatctca tagaaataaa gaaaaggagg aaagaggatg
     7441 ccacagatta gcaaagaagc cttgattgag caaatcaaag atggaatcat cgtttcttgt
     7501 caggctcttc ctcatgaacc gctttataca gaagcgggag gggtgattcc cttgctggtc
     7561 aaagcggctg agcaaggtgg agcagtcggt atccgagcaa acagtgttcg cgatatcaag
     7621 gaaattaagg aagtcactaa acttccaatc attgggatta tcaaacgtga ttatccacct
     7681 caggaaccct tcatcacggc tactatgaaa gaagttgatg aattggcaga actggacatc
     7741 gaggtgattg ctctggattg taccaagcgt gaacgctacg atggtttgga aattcaagag
     7801 ttcattcgtc aggttaagga gaaatatcct aatcagcttt tgatggctga tactagtatc
     7861 ttcgaagaag ggctagcagc tgtagaagca ggaattgact ttgtcggaac aaccttatca
     7921 ggctacacat cctacagtcc aaaagtagac ggtccagatt ttgaattgat taagaaactc
     7981 tgtgatgccg gtgtagatgt cattgcagaa ggaaaaattc atacaccaga acaagccaaa
     8041 caaatccttg aatatggagt gcgaggcatc gttgttggtg gcgccattac tagaccaaaa
     8101 gagattacag aacgcttcgt tgctagtctt aaataagatg tgagggggag ttttatgttt
     8161 aaagttttac aaaaagttgg aaaagctttt atgttaccta tagctatact tcctgcagca
     8221 ggtctacttt tggggattgg tggtgcactt tcaaacccaa ccacgatagc aacttatcca
     8281 atactagaca atagtatttt tcaatcaata ttccaagtaa tgagctctgc aggagaggtt
     8341 gtattcagta atttgtcact acttctctgt gtgggattat gtattggctt agcgaaacga
     8401 gataaaggaa ccgctgcgtt agcaggagta actggttact tagttatgac tgcaacgatc
     8461 aaagctttag taaaactttt tatggcagaa ggatctgcaa ttgatactgg agttattgga
     8521 gcattagttg tcggaatagt tgccgtatat ttgcacaacc gatataacaa tattcaatta
     8581 ccttccgctt taggattctt tggaggttca cgcttcgttc ctattgttac atcgttctct
     8641 tctatcttga ttggctttgt cttctttgtt atttggccac ctttccaaca acttcttgtt
     8701 tctacaggtg gatatatttc tcaggcgggt ccaattggaa cttttctata tggattttta
     8761 atgagacttt ctggagcagt aggcttacat catataattt accctatgtt ttggtatact
     8821 gaacttggtg gtgttgaaac tgttgcagga caaacagtgg ttggagctca aaaaatattt
     8881 tttgctcaat tagccgattt ggcccattct ggattattta cagaaggaac aaggtttttt
     8941 gcaggtcgtt tctcaacaat gatgttcggt ttaccggctg cctgtttagc gatgtaccat
     9001 agtgttccta aaaatcgtcg taaaaaatac gcgggtttgt ttttgggagt tgctttaaca
     9061 tcttttatta ccggtattac agaaccaatt gaatttatgt ttctattcgt tagtccggtt
     9121 ctatatgttg ttcacgcatt ccttgatggt gttagcttct ttattgcaga cgtcttaaat
     9181 atttcaatag gaaacacatt ttcaggaggt gtaatcgatt tcactttatt tggaattttg
     9241 caggggaacg ctaagacgaa ttgggttctt cagattccat ttggacttat ttggagtgtt
     9301 ttgtattata ttatttttag atggttcatt actcaattca acgttctaac gccagggcga
     9361 ggagaagaag tagattctaa agaaatttct gaatccgcag attcaacttc aaatactgca
     9421 gattatttaa aacaggatag cctacaaatt atcagagcct tgggtggatc aaataatata
     9481 gaagatgtag atgcttgtgt gacacgttta cgtgtagctg taaaagaagt taatcaagtt
     9541 gataaagcac ttttaaaaca aattggtgca gttgatgtct tagaagtgaa gggtggcatt
     9601 caagcaatat atggagcaaa agcaatctta tataaaaata gtattaatga aattttaggt
     9661 gtagatgatt aagtacttac tgacttaata aaaaacagag gagagtgatg gatgagtagg
     9721 atgaaatgaa atcgcataca agaaataaag aactcattat ccaagttgga tacgcttatt
     9781 acataggaga atacaaatga aatttagaaa attagcttgt acagtacttg cgggtgctgc
     9841 ggttcttggt cttgctgctt gtggcaattc tggcggaagt aaagatgctg ccaaatcagg
     9901 tggtgacggt gccaaaacag aaatcacttg gtgggcattc ccagtattta cccaagaaaa
     9961 aactggtgac ggtgttggaa cttatgaaaa atcaatcatc gaagcgtttg aaaaagcaaa
    10021 cccagatata aaagtgaaat tggaaaccat cgacttcaag tcaggtcctg aaaaaatcac
    10081 aacagccatc gaagcaggaa cagctccaga cgtactcttt gatgcaccag gacgtatcat
    10141 ccaatacggt aaaaacggta aattggctga gttgaacgac ctcttcacag atgaatttgt
    10201 taaagatgtc aacaatgaaa acatcgtaca agcaagtaaa gctggagaca aggcttatat
    10261 gtatccgatt agttctgccc cattctacat ggcaatgaac aagaaaatgt tagaagatgc
    10321 tggagtagca aaccttgtaa aagaaggttg gacaactgat gattttgaaa aagtattgaa
    10381 agcacttaaa gacaagggtt acacaccagg ttcattgttc agttctggtc aagggggaga
    10441 ccaaggaaca cgtgccttta tctctaacct ttatagcggt tctgtaacag atgaaaaagt
    10501 tagcaaatat acaactgatg atcctaaatt cgtcaaaggt cttgaaaaag caactagctg
    10561 gattaaagac aatttgatca ataatggttc acaatttgac ggtggggcag atatccaaaa
    10621 ctttgccaac ggtcaaacat cttacacaat cctttgggca ccagctcaaa atggtatcca
    10681 agctaaactt ttagaagcaa gtaaggtaga agtggtagaa gtaccattcc catcagacga
    10741 aggtaagcca gctcttgaat accttgtaaa cggatttgca gtattcaaca ataaagacga
    10801 caagaaagtc gctgcatcta agaaattcat ccagtttatc gcagatgaca aagagtgggg
    10861 acctaaagac gtagttcgta caggtgcttt cccagtccgt acttcatttg gaaaacttta
    10921 tgaagacaaa cgcatggaaa caatcagcgg ctggactcaa tactactcac catactacaa
    10981 cactattgat ggttttgctg aaatgagaac actttggttc ccaatgttgc aatctgtatc
    11041 aaatggtgac gaaaaaccag cggatgcttt gaaagccttc actgaaaaag caaacgaaac
    11101 aatcaaaaaa gctatgaaac aatagtcctt agttattcta taaaaagtag ttttttaaag
    11161 aacctaagag tgtatacccc cttttccctc tacacagata gtgtaagaaa agggggcttt
    11221 tgtttaaaat gtaagaaact gtcacgaaat taaaatgaag ttcttacata agcgaatcat
    11281 aaaaaatttc attttgattt taaaacagtt caagaaagtc aaaaaattat tctatttgaa
    11341 agagaggtgc cgactgtgaa agtcaataaa atccgtatgc gggaaacagt gatttcctac
    11401 gctttcctag caccagtatt attcttcttt gtcatctttg tgttggctcc gatggtgatg
    11461 ggcttcatta caagtttctt taactactca atgactaaat ttgagtttgt aggcttggat
    11521 aactatatcc gtatgtttaa agatcctgtc tttacaaaat ctctgattaa cacagttatt
    11581 ttggttattg gatctgtacc agttgttgtt ctattctcac tctttgtagc atctcagacc
    11641 tatcatcaaa atgtcattgc cagatccttc taccgtttcg tcttcttcct tcctgttgta
    11701 acgggtagtg ttgccgtgac agttgtttgg aaatggattt atgacccact atcagggatt
    11761 ctaaactttg tccttaagtc cagccacatc atcagccaaa acatttcttg gttgggagat
    11821 aaaaactggg cattgatggc gattatgatt attctcttga ccacttcagt tggtcagccc
    11881 atcatccttt atatcgctgc catggggaat attgacaatt cactggttga agcggcgcgt
    11941 gttgatggtg caactgagtt tcaagttttt tggaagatta aatggccaag ccttcttcca
    12001 acaactcttt atattgcaat catcacaaca attaactcat tccagtgttt cgccttgatt
    12061 cagcttttga catctggtgg tccaaactac tcaacaagta ccttgatgta ctacctttac
    12121 gaaaaagcct tccaattgac agaatacggc tatgccaaca caattggtgt cttcttggca
    12181 gtcatgattg ctatcgtaag ctttgttcaa tttaaagtac ttggaaacga cgtagaatac
    12241 taaagaaagg agacagctat gcaatctaca gaaaaaaaac cattaacagc ctttactgtt
    12301 atttcaacaa tcattttgct cttgttgact gtgctgttca tctttccatt ctactggatt
    12361 ttgacagggg cattcaaatc acaacctgat acaattgtta ttcctcctca gtggttccct
    12421 aaaatgccaa ccatggaaaa cttccaacaa ctcatggtgc agaaccctgc cttgcaatgg
    12481 atgtggaact cagtatttat ctcattggta accatgttct tagtttgtgc aacctcatct
    12541 ctagcaggtt atgtattggc taaaaaacgt ttctatggtc aacgcattct atttgctatc
    12601 tttatcgctg ctatggcgct tccaaaacaa gttgtccttg taccattggt acgtatcgtc
    12661 aacttcatgg gaatccacga tactctctgg gcagttatct tgcctttgat tggatggcca
    12721 ttcggtgtct tcctcatgaa acaatttagt gaaaatattc ctacagagtt gcttgaatca
    12781 gctaaaatcg acggttgtgg tgagattcgt accttctgga gtgtagcctt cccgattgtg
    12841 aaaccagggt ttgcagccct tgcaatcttt accttcatca atacttggaa tgactacttc
    12901 atgcagttgg taatgttgac ttcacgtaac aatttgacca tctcacttgg ggttgcgacc
    12961 atgcaggctg aaatggcaac caactatggt ttgattatgg caggagctgc ccttgctgct
    13021 gttccaatcg tcacagtctt ccttgtcttc caaaaatcct tcacacaggg tattactatg
    13081 ggagcggtca aaggataata ctctgcgaaa atcgaatgca aactacgtca gcttcacctt
    13141 gccatactta agtattgcct gcggttagct tcctagtttg ttcttcaatt ttcattgagt
    13201 ataggaaaat caatctatca agatacagaa gtatatttta tagatttaga gaatatagaa
    13261 gttataagtg tctacaaaat ggagggtatg cagttacttt atgaagtttt gtcagacact
    13321 tatcaactta agaatgattt tagttaatta tcagaaacga aggaaagagt atgatttttg
    13381 acgatttgaa aaacatcacc ttttacaaag ggattcatcc caatttagac aaagctatcg
    13441 actacctcta ccaacatcgt aaagattcat tcgaattagg aaagtatgag attgatggag
    13501 ataaggtctt tctagttgtt caggaaaatg tcctcaatca agttgagaat aatcaatttg
    13561 aacaccataa gaactatgca gatttgcatt tgctgataga agggcatgaa tattcgagct
    13621 acggttcacg tatcaaagac gaggcagtag cattcgacga agcgactgac attggctttg
    13681 ttcattgtca tgaacactac ccactcttgt tgggttatca taattttgcg attttcttcc
    13741 caggtgagcc acatcagcca actggctatg caggtatgga agaaaaggtt cgaaaatatc
    13801 tctttaaaat tttgattgat taaaaatagg atgaattgtt tttttgtaaa gctttgacaa
    13861 tactctacca tgaaattgat ctttatgagg tagagaaatg agaataaaat atttaaaaat
    13921 tggtatcttc taagcatgct gcaagagcta gtttcttaga tggacaggaa attacagttg
    13981 atgagatgtc ctggataatt aatggcattg tgaatgcatt gattggtaga tacataaaat
    14041 taggtactta tgcagctaag tatggtattg gtatagcacg ctcgatctta agtagggcag
    14101 ctgcaactgc agcagcaaga gtaggattac tgaccaagat ttctggatgg attttacgag
    14161 tagctgtgaa tgtagctgat gtatatggta atttcgccaa caatattgct gcagcttggg
    14221 atgcatatga taaaattcct aacaatggtc gtataaactt ttaaaatacg agaatgaaag
    14281 cactttgtat ttttttattg aatatgttag cttggacagt gcttgcaatg ataattcgtg
    14341 gagggctaga tggatttgat aggcatactt ggagtactat tttaattgct tcgctgttcg
    14401 gggtatatga ttataagccc atagataaaa atagaaaaaa gtccaaaaga aaaaagaaaa
    14461 aatagatttg ttcatggtag ggacttatga aagctttact gacaaaaaag aaaacagttt
    14521 acaaagaaaa atgatggagg agcaaacatg gcacaaaaag gagtaagcct tatcaaggca
    14581 gcatttgata cagataactt tctcatgcgt tttagtgaga aggtcttgga catcgtgaca
    14641 gccaatcttc tttttgtcgt ctcttgttta cccatcgtga cgattggagt ggctaaaatc
    14701 agcctctacg agaccatgtt cgaagttaag aagagcagac gggtgcctgt ttttaaaatc
    14761 tatctaagat ctttcaagca aaatctgaaa ctaggtcttc agctgggttt aatggagtta
    14821 ggaattgtgt ttcttaccct ttcagatctc tatcttttct ggggtcaaac agctctgccc
    14881 ttccaattgc tgaaagccat ttgtttaggt attctgattt ttcttactat cgtgatgctg
    14941 gctagttacc ctatcgcggc acgttatgac ctatcttgga aagaaattct tcaaaaagga
    15001 ttgatgttgg ctagttttaa ctttccttgg ttcttcctca tgttagccat tcttgtcctc
    15061 attgtgatgg ttctttatct gtccgccttc agtctactct taggtggctc agtcttccta
    15121 ctttttgggt ttggactatt ggtctttatc cagactggat tgatggagaa aattttcgca
    15181 aaataccaat aggagcttta tttctgaaac tactttcaaa ggctccaaac gctattctat
    15241 aagcgagaaa ctaaaatcta agtgtctata agatattgaa agccttttcg gtaaagtgta
    15301 tactaaagaa gtaaagaaaa atctgcttta gcagaaaata aaaataatag gagaaaatct
    15361 atgtcagatt tgaaaaaata cgaaggtgtc attccagcct tctacgcatg ttatgatgag
    15421 caaggagaag taagtccaga gcgtacgcgt gccttggttc aatacttcat tgataaaggt
    15481 gttcaaggtc tttatgtcaa tggttcttct ggtgaatgta tctaccaaag cgttgaagat
    15541 cgcaagttga ttttggaaga agtcatggcg gtagctaaag gtaaattgac cattattgcc
    15601 catgttgcct gcaacaatac taaagacagt atggaacttg ctcgccatgc tgaaagcttg
    15661 ggagtagatg ctattgcaac gattccacca atttatttcc gcttgccaga atactcagtt
    15721 gccaaatact ggaacgatat cagttctgca gctccaaaca cagactacgt gatttacaac
    15781 attcctcaat tggcaggggt tgctttgact ccaagccttt acacagaaat gttgaaaaat
    15841 cctcgtgtta tcggtgtgaa gaactcttct atgccagttc aagatatcca aacctttgtc
    15901 agccttggtg gggaagacca tatcgtcttt aacggtccag atgaacagtt cctaggtggt
    15961 cgcctcatgg gtgccaaagc tggtatcggt ggtacttatg gtgctatgcc agaactcttc
    16021 ttgaaactca accaattgat tgcggataaa gatttagaaa cagcgcgtga gttacagtat
    16081 gctatcaacg ctatcattgg taaattgact gctacacatg gaaatatgta cggtgtcatc
    16141 aaagaagttt tgaagatcaa tgaaggcttg aatattggtt ctgttcgttc accattgaca
    16201 ccagtgactg aagaagatcg tccagttgta gaagcggctg ctgccttgat tcgtgaaacc
    16261 aaggagagct tcctctaatc taaaaggagg tatttatgac atactacgtt gcaattgata
    16321 tcggtggaac caacatcaag tatggtttgg ttgatcaaga ggggcaactt cttgaatcgc
    16381 atgaaatgcc aactgaggcg cataagggtg gacctcatat cttacaaaag accaaagata
    16441 tcgtagctag ttatttagaa aaaggcccag tagcaggtgt tgccatatct tctgctggga
    16501 tggtggatcc ggataagggt gagattttct atgctgggcc gcaaatccct aactacgcag
    16561 gcacccagtt caaaaaggaa atcgaagaaa gctttactat tccttgtgag attgaaaatg
    16621 atgtcaactg tgcaggtctt gctgaggcag tatctggttc aggcaaggga gcaagtgtga
    16681 cactttgctt gaccattgga accggtatcg gtggttgctt gattatggat aggaaagtct
    16741 tccatggttt tagcaattca gcctgtgaag tcgggtatat gcatatgcag gatggagctt
    16801 ttcaagactt ggcttctaca acagctttag tgaaatatgt agctgaagcc catggagaag
    16861 atgttgatca gtggaatggc cgtagaattt tcaaagaagc cactgaagga aacaaaatct
    16921 gcatggaagg tattgaccgt atggttgact atctaggaaa aggtctggca aatatttgct
    16981 acgttgccaa tccagaagtg gttattcttg gtggtggtat catggggcaa gaggctatcc
    17041 tcaaacctaa gatccgcaca gccttgaaag aggctttggt accaagttta gcagaaaaaa
    17101 cacgattaga atttgcccat caccaaaata cagcagggat gttgggtgca tattatcatt
    17161 ttaagacaaa acaatcctag tttggctcag ccaaactagg attttcttac acgtttttgt
    17221 ctacgatagc cgttgagttt tttattttcc cagtagctat taaagatttt ttccttgctt
    17281 tcgcgattga tttccaaaaa gtaggcataa atcaaatcga taaagaagag cataggaagt
    17341 tgagcggata ttcgttggat ataggagggt tggctgtggg tggctacaag aacagtctct
    17401 gtataggtct ggctatcttt attgggaaca cttgtaaaga gtacagtctt tgcccccatc
    17461 tccttggcat ctaatagact atctaaaata gaaggagttg agcctgaaag tgagaagccc
    17521 agtactagac aattttcatc catgatgctg gttgtccagg caaagccgtc ttggtctgtc
    17581 aaagcttcgc agaccacacc tagtcgcata aaacgtaatt tcatttcacg ggcgacgagg
    17641 ccagaactcc ctgttccaaa gaagtagata cgctcagcat cttcgattag ctgggcaatt
    17701 cgctctagtt ggatttcgtc aatcaagtct tgtgtttgtt ccctcatatt gctataactt
    17761 ctgaggactc gtttggtcag tggactgtgc ttggagactc ggttggcttg attttctgcc
    17821 tgatgttggt attggaaaat aaattctcgg tagccagtaa agccacactt tttagcaaag
    17881 cgggtcaaag cagcttgaga aatatgtaat ttttgggtga cttgttgaga agataaatca
    17941 tctgtaatcg tttcagcttg caaaaaatag cgagcgattt cttgctctag gtctgtcatt
    18001 tcttcaaaat gtgaatcaat gatagttgcg atatctggtt tgtccatagg gaaagctcct
    18061 ttacatgagt catactggaa gactagatca gggaatagtc acacttcatt ataacacata
    18121 atataaggat agataaataa aaacgcatct ctgttttaaa aacgaaaaaa tcgaaaaagc
    18181 ttctctcttt tccataattt tctactcaaa ttgtggtaca attaagagta agattttaag
    18241 ttagaaatga gactgatttg tatgagaaaa tttaacagcc attcgattcc gattcggctt
    18301 aatttattgt tttcaatcgt cattttactc tttatgacca ttattggtcg tttgttgtat
    18361 atgcaggttt tgaacaagga tttttacgaa aaaaagctag cctcagctag tcagaccaag
    18421 attacaagca gttcagcccg tggggaaatt tatgatgcta gtggaaaacc tttggtagaa
    18481 aatacgttaa agcaggttgt ttcctttacg cgtagcaata aaatgacggc tacagactta
    18541 aaagaaacag ctaaaaagtt actgacttat gtgagcatca gttctccaaa tttgacaaaa
    18601 cgccagctgg cggattacta tttggctgat cctgaaatct ataaaaaaac agtggaagct
    18661 ctcccaagcg agaaacgctt ggattcagat ggcaatcgtc tatccgaatc agaactgtat
    18721 aacaatgcgg tcgatagtgt ccaaacaagt caactaaact atacagagga tgaaaagaaa
    18781 gaaatctatc tttttagtca gttaaatgct gttggaaact ttgcgacagg aaccattgct
    18841 acagatcctc taaatgattc tcaggtggct gttattgcct ctatttcaaa ggagatgcct
    18901 ggcattagta tttctacttc ttgggataga aaggttttgg aaacttccct ttcttctata
    18961 gttgggagtg tatccagtga aaaagctggt ctcccagcgg aagaagcaga agcctatctt
    19021 aaaaaaggct attctctaaa tgaccgtgta ggaacctcct atttggaaaa gcaatatgaa
    19081 gagaccttac aaggaaaacg atcggtaaaa gaaatccatc tggataaata tggcaatatg
    19141 gaaagcgtgg atacaattga ggaaggtagt aagggaaaca atatcaaact gaccattgat
    19201 ttggccttcc aagatagcgt ggatgctttg ctgaaaagtt atttcaattc tgagctagaa
    19261 aatggtggag ccaagtattc tgaaggtgtc tatgcagtcg cccttaaccc aaaaacaggt
    19321 gcggttttgt ctatgtcagg gattaaacat gacttgaaaa cgggagagtt gacgcctgat
    19381 tccttgggaa cggtaaccaa tgtctttgtt ccaggttcgg ttgtcaaggc ggcgaccatc
    19441 agctcaggtt gggaaaatgg agtcttgtca ggaaaccaga ccttgacaga ccagtccatt
    19501 gtcttccaag gttcagctcc catcaattct tggtatactc aggcttacgg ttcattccct
    19561 atcacagcgg tccaagctct ggagtattca tcaaatacct atatggtcca aacagcctta
    19621 ggtcttatgg ggcaaaccta tcaacccaat atgtttgtcg gcaccagcaa tctagagtct
    19681 gctatggaga aactgcgttc aacctttggc gaatatggct tgggtactgc gacaggaatt
    19741 gacctaccag atgaatctac tggatttgtt cccaaagagt atagctttgc taattacatt
    19801 actaatgcct ttgggcagtt tgataactat acgccgatgc agttggctca gtatgtagca
    19861 actattgcaa ataatggtgt tcgtgtggct cctcgtattg ttgaaggcat ttatggtaat
    19921 aatgataagg gaggactggg tgacttgatt cagcaactgc aaccgacaga gataaataag
    19981 gtcaatatat ccgactccga tatgagcatc ttgcaccaag gtttttatca ggttgcccat
    20041 ggtactagtg gattgacaac tggacgtgcc ttttcaaatg gtgccttggt atccattagc
    20101 ggaaaaacag gtacagccga aagctatgtg gcagatggtc agcaagcaac caataccaat
    20161 gcggtggcct atgccccatc tgataatccc caaatcgctg tcgcagtggt ctttcctcat
    20221 aataccaatc taacaaatgg tgtaggacct tccattgcgc gtgacattat caatctgtat
    20281 caaaaatacc atccaatgaa ctagaaagga aattatgctt tatccaacac ctattgccaa
    20341 gttgattgac agttattcta agttaccagg tatcgggatt aagacggcta cgcgtctggc
    20401 cttttatacg attgggatgt ctgctgatga tgtcaatgaa tttgcaaaaa atctcctttc
    20461 tgctaagaga gaattgacat attgttctat ttgtggacgt ttgacagacg acgatccttg
    20521 ttctatctgt actgatccga ctcgtgacca gacaacaatt ttagttcttg aggatagtag
    20581 agatgtggca gccatggaaa atatccaaga ataccatgga ctctatcatg tcctgcatgg
    20641 cctcatttct cctatgaatg gtatcagtcc ggacgatatc aatctcaaga gccttatgac
    20701 tcgtcttatg gatagtgagg tttcagaagt gattgtggcg actaatgcta cagcggatgg
    20761 tgaagcgact tccatgtatc tttcacgttt gctcaagcca gctggtatca aggttacgcg
    20821 tctagcacga ggtctcgctg tgggagcgga cattgagtat gcggacgaag tgacactctt
    20881 acgagcgatt gaaaatcgga cagagttgta agtgtaggca aatttacgaa ctcccttcat
    20941 ttataaaaaa tcaaagaggc tgaaaatcgt tcctatcggc ctctttttgt atagtgtgat
    21001 gagtaggatc gggttcaagt tttaaaaaac caagcaaata tgatatacta aagagcgagt
    21061 attctagtag aattaggaca aataatatga aacaaacgat tattctttta tatggtggac
    21121 ggagtgcgga acgcgaagtc tctgtccttt cagctgagag tgtcatgcgt gcggtcaatt
    21181 acgaccgttt cacagtcaag actttcttta tcagtcagtc aggtgacttt atcaaaacac
    21241 aggaatttag tcatgctccg gggcaagaag accgtctcat gaccaatgaa accattgatt
    21301 gggataagaa agttgcacca agtgctatct acgaagaagg tgcagtggtc tttccagtcc
    21361 ttcacgggcc aatgggagaa gatggctctg ttcaaggatt cttggaagtt ttgaaaatgc
    21421 cttacgttgg ttgcaacatt ttgtcatcaa gtcttgccat ggataaaatc acgactaagc
    21481 gtgttctgga atctgctggt attgcccaag ttccttatgt ggctatcgtt gaaggcgatg
    21541 atgtgactgc taaaatcgct gaagtggaag aaaaattggc ttatccagtc ttcactaagc
    21601 cgtcaaacat ggggtctagt gtcggtattt ctaagtctga aaaccaagaa gaactccgtc
    21661 aagccttaaa acttgccttc cgatatgaca gccgtgtctt ggttgagcaa ggagtgaatg
    21721 cccgtgaaat tgaggttggc ctcttgggta actacgatgt caagagcacg ctacctggag
    21781 aagttgtcaa ggacgttgcc ttttatgact acgatgccaa gtatattgat aacaagatta
    21841 ctatggatat tcctgccaaa atcagtgatg atgtggtagc tgtcatgcgt caaaatgcag
    21901 aaacagcctt ccgtgccatt ggtggccttg gtctatctcg ttgcgatttc ttctatacag
    21961 ataagggaga gatttttctc aacgagctca ataccatgcc aggtttcacc cagtggtcta
    22021 tgtacccact actttgggac aatatgggga tcagctaccc agaactaatc gagcgtttgg
    22081 ttgaccttgc caaggaaagt tttgacaagc gcgaagcgca tttgatataa aatgaaagag
    22141 agggtagaag ccagaaccat cactgcaagg tgactagagt tctcggactt cagccctttt
    22201 taaaggagta gaaatgaaat taacaatcca tgaagttgcc caagttgttg gagccaaaaa
    22261 tgatatcagt atctttgagg acacccagtt agaaaaagct gagtttgata gtcgtttgat
    22321 tggaactgga gatttatttg tgcccctaaa aggtgtgcgt gacggtcatg actttatcga
    22381 aagagctttt gaaaatggtg cggcagcaac cctgtctgag aaagaggttg caaatcatcc
    22441 ctacattcta gtagatgatg ttttgactgc ctttcaacaa ctagctgcct actatcttga
    22501 aaaaacagct gttgatgtct ttgcggttac gggttcaaat ggcaagacaa cgactaagga
    22561 tatgttggcg catttactgt caacaagata caagacctac aaaacacaag gcaattacaa
    22621 taatgagatt ggccttcctt acacagttct ccacatgcct gaaggaacag aaaagttggt
    22681 cttggagatg gggcaggacc acttgggaga tattcatctc ttgtctgaat tggctcgtcc
    22741 aaaaacagcc atcgtgacct tggttggaga agctcatttg gcctttttca aagatcgttc
    22801 tgagattgct aaaggaaaaa tgcaaattgc agacggaatg gcttcaggtt ccttgctttt
    22861 agcgccggct gaccctatcg tagaggacta tttgccaact gataaaaagg tggttcgttt
    22921 tggtcaagga gcagagctgg aaattactga cttggttgag cgcaaagata gtctgacctt
    22981 caaggccaat ttcttagagc aagtccttga tttgccagta actggcaagt acaatgcgac
    23041 aaatgctatg attgcatcct atgttgcctt gcaagaagga gtttcagagg agcaaattcg
    23101 tttggccttc caacatcttg aattgacgcg taaccgtacc gagtggaaga aagcagccaa
    23161 tggagcagac atcttgtcag atgtttacaa tgccaatcca actgctatga agctgatttt
    23221 agagaccttc tctgccattc cagccaatga aggtggcaag aaaattgcag tgttggcgga
    23281 tatgaaggaa cttggtgtcc agtctgttca acttcataat cagatgattt tgagcctttc
    23341 gccagatgtg cttgatactg ttattttcta cggagaagat attgctgaat tagcccaact
    23401 tgctagtcaa atgttcccaa tcggacacgt ttattacttc aagaaaacag aagaccaaga
    23461 ccaatttgaa gacctagtta agcaggtcaa agaaagcctt ggggctcatg accaaatcct
    23521 gctcaaaggc tctaactcta tgaatctagc caagttggta gaaagtttag aaaatgaaga
    23581 caagtgattt tgtcaagtat ttgcaaagaa tgattgccat tacagatact ggattaacct
    23641 ttacaaaaga tccgtttgac cgtgagcgct acgaagactt gcgagacctt ctatctgaaa
    23701 tgttgaatca agcatcagac cttgattccg aagaagtggc agaagtcttg aagccaactt
    23761 ctgcttatgc gactccctta atggacgtcc gtgcttggat tgttgaggac gaaaagattt
    23821 gtctggttag gggacaagga gaggatagtt gggctttgcc aggtggcttt ggtgaagtcg
    23881 gctattctcc aactgaaaat attctcaagg aaattgaaga agaaaccggt tttaaagcca
    23941 aagttgaaag actgctagct gtttttgata ccaatcgttt ccaactacag agcaaacaat
    24001 atgcaaagtt tgtttttgaa tgtaagcttc tcgatggaca attccaagaa aatcaagaaa
    24061 tcgctgacct tcaatttttt gcaattgacc cactgccgaa tttatctgaa aaacgcatta
    24121 ccaaggagca aatcgagatt ctttggcagg tttatcaagg tcagagggag caatatcttg
    24181 actaagaaga tgattatcgt atttctaaat tcatttttct taagtagcat ggtataataa
    24241 aatgcaggaa aattttgaat catgaggaag actagatgaa tttatgggat attttcttta
    24301 cgactcaggc aaccgagccg cccaaatttg accttttttg gtatgttagc ctatttacgc
    24361 tcttagcctt aaccttttat acagcccatc gctatcgtga aaagaaggtt taccaacgat
    24421 ttttccaaat cttgcagact gttcagttaa tccttcttta tggttggtac tgggtcaatc
    24481 atatgccact gtcagaaagc ctaccctttt accattgccg tatggctatg tttgtggtac
    24541 tcttgcttcc tggtcagtcc aaatataaac aatactttgc attattggga acatttggga
    24601 cattagcagc ctttgtttat ccagtgccag atgcttaccc ttttccacat atcaccattc
    24661 tatcctttat ctttggtcat ttagcactct tggggaactc tctagtttat ctattgagac
    24721 agtataatgc gcgattgctg gatgtgaagg gaatttttct catgaccttt gccctaaatg
    24781 ccttgatttt tgtggtcaat ttggtgacag gtggcgatta cggatttttg acaaaaccgc
    24841 cattggttgg ggatcacggt ctagtagcta attatttact tgtttcaatt gtgctggtag
    24901 ctactatcag tttgactaag aaaatcttag aattcttttt agctcaagaa gcagaaaaaa
    24961 tgattgcaaa ggaagcttaa cacagagctt tcttttttgc tcttagagag tttttacaag
    25021 cagcttataa aataagaatt tctgaataga caaactcaaa aaatggctgg gaaatttagg
    25081 aaaaaagcaa gcacgattaa attttttgtg ttataatatt ttgtgaatag ctatgcctat
    25141 gtttagctat ggaataatac gaagtgcgaa acttggaaga tagagaggaa gcgatgtaat
    25201 ggctagagaa ggctttttta caggtctaga tattggaaca agctctgtca aggtgcttgt
    25261 ggccgagcag agaaatggtg aattaaatgt aattggcgtg agtaatgcca aaagtaaagg
    25321 tgtaaaggat ggaattattg ttgatattga tgcagcagca actgctatca agtcagccat
    25381 ttcccaagcg gaagaaaagg caggcatttc gattaaatca gtaaatgtcg gcttgcctgg
    25441 taatcttttg caggtagaac caactcaggg gatgattcca gtaacatctg atactaagga
    25501 aattacggat caagatgttg aaaatgttgt caaatcagct ttgacaaaga gtatgacacc
    25561 tgaccgtgaa gtcattacct ttattcctga agaatttatt gtggatggtt tccaagggat
    25621 tcgtgaccca cgtggcatga tgggggttcg ccttgaaatg cgtggtttgc tttatacagg
    25681 acctcgtact atcttgcaca atttgcgtaa gacggttgag cgtgcaggtg ttcaggttga
    25741 aaatattatc atttcaccac tagcaatggt tcagtctgtt ttgaatgaag gggaacgtga
    25801 atttggtgct acagtgattg atatgggggc aggtcaaacg actgtcgcta caatccgtaa
    25861 tcaagaactc cagttcacac atattctcca agaaggtgga gattatgtaa ctaaagatat
    25921 ctccaaggtt ttgaaaacct ctcgcaaatt agcggaaggc ttgaaactga attacgggga
    25981 agcctatccg cctcttgcaa gcaaagaaac cttccaagta gaggttattg gagaagtgga
    26041 agcagtcgaa gtgacggaag cctacttgtc agaaattatt tctgcacgaa tcaagcacat
    26101 ccttgaacaa atcaagcaag aattagatag aaggcgtcta ttggacctcc ctggtggtat
    26161 tgtcttaatc ggtgggaatg ccattttacc aggtatggtt gagcttgctc aggaagtctt
    26221 tggcgtccgt gtcaagcttt atgttccaaa tcaagttggt atccgtaatc cagcctttgc
    26281 gcatgtgatt agtttatcag aatttgcggg tcaattaaca gaagttaatc ttttggctca
    26341 gggagcgata aaaggtgaga atgacttaag tcatcagcca attagttttg gtgggatgct
    26401 gcaaaaaaca gctcagtttg tacaatcaac gcctgttcaa ccagctcctg ctccagaagt
    26461 agagtcggtg gcgcctacag aaccaatggc ggatttccaa caagcttcac aaaataaacc
    26521 gaaattagca gatcgtttcc gtggcttgat cggaagcatg tttgacgaat aaagaggaaa
    26581 aataaattat gacattttca tttgatacag ctgctgctca aggggcagtg attaaagtaa
    26641 ttggtgtcgg tggaggtggt ggcaatgcca tcaaccgtat ggtcgacgaa ggtgttacag
    26701 gcgtagaatt tatcgcagca aacacagatg tacaagcatt gagtagtaca aaagctgaga
    26761 ctgttattca gttgggacct aaattgactc gtggtttggg tgcaggaggt caacctgagg
    26821 ttggtcgtaa agccgctgaa gaaagcgaag aaacactgac ggaagctatt agtggtgccg
    26881 atatggtctt catcactgct ggtatgggag gaggctctgg aactggagct gctcctgtta
    26941 ttgctcgtat cgccaaagat ttaggtgcgc ttacagttgg tgttgtaaca cgtccctttg
    27001 gttttgaagg aagtaagcgt ggacaatttg ctgtagaagg aatcaatcaa cttcgtgagc
    27061 atgtagacac tctattgatt atctcaaaca acaatttgct tgaaattgtt gataagaaaa
    27121 caccgctttt ggaggctctt agcgaagcgg ataacgttct tcgtcaaggt gttcaaggga
    27181 ttaccgattt gattaccaat ccaggattga ttaaccttga ctttgccgat gtgaaaacgg
    27241 taatggcaaa caaagggaat gctcttatgg gtattggtat cggtagtgga gaagaacgtg
    27301 tggtagaagc ggcacgtaag gcaatctatt caccacttct tgaaacaact attgacggtg
    27361 ctgaggatgt tatcgtcaac gttactggtg gtcttgactt aaccttgatt gaggcagaag
    27421 aggcttcaca aattgtgaac caggcagcag gtcaaggagt gaacatctgg ctcggtactt
    27481 caattgatga aagtatgcgt gatgaaattc gtgtaacagt tgttgcaacg ggtgttcgtc
    27541 aagaccgcgt agaaaaggtt gtggctccac aagctagatc tgctactaac taccgtgaga
    27601 cagtgaaacc agctcattca catggctttg atcgtcattt tgatatggca gaaacagttg
    27661 aattgccaaa acaaaatcca cgtcgtttgg aaccaactca ggcatctgct tttggtgatt
    27721 gggatcttcg ccgtgaatcg attgttcgta caacagattc agtcgtttct ccagtcgagc
    27781 gctttgaagc cccaatttca caagatgaag atgaattgga tacacctcca tttttcaaaa
    27841 atcgttaagt aaatgaatgt aaaagaaaat acagaacttg tttttcgaga agttgcagag
    27901 gctagtctga gtgctcatcg agagagtggt tcggtctctg tcattgcagt taccaagtat
    27961 gtagatgtac cgacagcgga agccttgctt ccgctaggtg ttcatcatat cggtgaaaat
    28021 cgtgtagata agtttctgga aaaatatgaa gctttaaaag atcgagatgt gacttggcat
    28081 ttgattggta ccttgcaaag acgtaaggtg aaagatgtca ttcaatacgt tgattatttc
    28141 catgcattgg actcagtaaa gctagcaggg gaaattcaaa aaagaagtga ccgagtcatc
    28201 aagtgtttcc ttcaagtaaa tatttctaaa gaagaaagca aacacggttt ttcgagagag
    28261 gaactgctgg aaatcttgcc agagttagcc agactagata agattgaata tgttggttta
    28321 atgacgatgg caccttttga ggctagcagt gagcagttga aagagatttt caaggcgacc
    28381 caagatttac aaagagaaat tcaagagaaa caaattccaa atatgcctat gaccgagtta
    28441 agtatgggaa tgagtcgtga ttataaagaa gcgattcaat tcggttccac ttttgttcgt
    28501 ataggtacat cattttttaa gtaggagaga accatgtctt taaaagatag attcgataga
    28561 tttatagatt attttacgga ggatgaggat tcaagtctcc cttatgaaaa aagagatgag
    28621 cctgtgttta ctccagtaaa ttcttcacag gaaccggctc tcccaatgaa tcaaccttca
    28681 cagtcggctg gtacaaaaga gaacaatatc accagacttc atgcaagaca acaggaattg
    28741 gcaaatcaga gtcagcgtgc aacggataag gtcattatag atgttcgtta tcctagaaaa
    28801 tatgaggatg caacagaaat tgttgattta ttggcaggaa acgaaagtat cttgattgat
    28861 tttcagtata tgacagaggt gcaggctcgt cgttgtttgg actatttgga tggagcttgt
    28921 catgttttag ctggaaattt gaaaaaggta gcttctacca tgtatttgtt gacaccagtg
    28981 aatgttattg taaatgttga agatatccgt ttaccagatg aagatcaaca gggtgagttc
    29041 ggttttgata tgaagcgaaa tagagtacga taatgatttt tttaattcgt atgatttata
    29101 atgcagtgga tatttactcc ctgattttgg tagccttcgc tgtcatgtct tggtttccag
    29161 gtgcctacga atccagttta ggtcgttgga ttgtagcgtt ggtgaaacca gtgcttgctc
    29221 ccttgcaacg cctgccttta cagatagcgg gtcttgattt atctgtttgg gtcgcgattg
    29281 ttttggttcg atttttagga gaaaacctag tgcgttttct ggcgatgata ggatgaataa
    29341 agggatttat cagcatttct ccatagaaga tcgtccattt cttgacaagg gaatggaatg
    29401 gataaagaag gtagaagata gctatgctcc ttttttaact ccttttatca atcctcatca
    29461 ggagaagcta ttaaagattt tggccaaaac ctatggtctt gcttgtagca gtagtgggga
    29521 attcgtctcg agtgagtatg ttcgagtttt attataccca gattatttcc aaccagagtt
    29581 ttcagatttt gaaatatctc tccaggaaat tgtgtattcc aataaatttg aacatttaac
    29641 gcatgctaag attttaggga cagtcatcaa tcaattaggg attgaacgga aactttttgg
    29701 agatatccta gtagatgaag aacgggcgca gattatgatt aatcagcagt ttcttcttct
    29761 ctttcaagat ggactaaaga aaattggtcg tatacctgtt tcgctggagg aacgtccttt
    29821 caccgagaaa atagataagc tagaacagta tcgagaactg gatttatctg tgtctagttt
    29881 tcgattagat gttctttgtt caagttggag acttgattag tgtgagaaaa tttggtcgct
    29941 tgagattact tcaagataag ggacaaacga aaaaagagaa gaaaaaaata accgtccagt
    30001 tattattaag taagtgagga atagaatgcc aattacatca ttagaaataa aggacaagac
    30061 ttttggaact cgattcagag gttttgatcc agaagaagtc gatgaatttt tagatattgt
    30121 ggttcgtgat tacgaagatc ttgtgcgtgc gaatcatgat aaaaatttgc gtattaagag
    30181 tttagaagag cgtttgtctt actttgatga aataaaagat tcattgagcc agtctgtatt
    30241 gattgctcag gatacagctg agagagtgaa acaggcggcg catgaacgtt caaacaatat
    30301 cattcatcaa gcagagcaag atgcgcaacg cttgttggaa gaagctaaat ataaggcaaa
    30361 cgagattctt cgtcaagcaa ctgataatgc taagaaagtc gctgttgaaa cagaagaatt
    30421 gaagaacaag agccgtgtct tccaccaacg tctcaaatct acaattgaga gtcagttggc
    30481 tattgttgaa tcttcagatt gggaagatat tctccgtcca acagctactt atcttcaaac
    30541 cagtgatgaa gcctttaaag aagtggttag cgaagtactt ggagaaccga ttccagctcc
    30601 aattgaagaa gaaccaattg atatgacacg tcagttctct caagcagaaa tggaagaatt
    30661 acaagctcgt attgaggtag ccgataaaga attgtctgaa tttgaagctc agattaaaca
    30721 ggaagtggaa actccaactc ctgtagtgag tcctcaagtt gaagaagagc ctctgctcat
    30781 ccagttggcc caatgtatga agaaccagaa gtagctccag tgcatccgac aggtccaaca
    30841 ccagctacag aaactgttga ttcagcaccg ggatttgaag caccgcaaga atctgttaca
    30901 attttataag aaatattctg agaacaatat cttatcctta tattcccagc gagcaggaga
    30961 tggtgtgagt cctgcattcc ctatcgataa gattatcctc tcaaactatc aagtctgaat
    31021 ctagtaagat ttgacgttcc ccacgttacg ggataagagg gagaaagact aaaacttttt
    31081 ccgaataaag gtggtaccac gattttcgtc ctttttggaa gtcgtggttt ttaatttgtt
    31141 attatttata aaggagatac catgaaactc aaagacaccc ttaatcttgg gaaaactgaa
    31201 ttcccaatgc gtgcaggcct tcctaccaaa gagccagttt ggcaaaagga atgggaagat
    31261 gcaaaacttt atcaacgtcg tcaagaattg aaccaaggaa aacctcattt caccttgcat
    31321 gatggccctc catacgctaa cggaaatatc cacgttggac atgctatgaa caagatttca
    31381 aaagatatca ttgttcgttc taagtctatg tcaggatttt acgcaccatt tattcctggt
    31441 tgggatactc atggtctgcc aatcgagcaa gtcttgtcaa aacaaggtgt caaacgtaaa
    31501 gaaatggact tggttgagta cttgaaactt tgccgtgagt acgctctttc tcaagtagat
    31561 aaacaacgtg aagattttaa acgtttgggt gtttctggtg actgggaaaa tccatatgtg
    31621 accttgactc ctgactatga agcagctcaa attcgtgtat ttggtgagat ggctaataag
    31681 ggttatatct accgtggtgc taagccagtt tactggtcat ggtcatctga gtcagccctt
    31741 gctgaagcag agattgaata ccatgacttg gtttcaactt ccctttacta tgccaacaag
    31801 gtaaaagatg gcaaaggagt tctagataca gatacttata tcgttgtctg gacaacgact
    31861 ccatttacta tcacagcctc tcgtggtttg acggttggtg cagatattga ttacgttttg
    31921 gttcaacctg ctggtgaagc tcgtaagttt gtcgttgctg ctgaattatt gactagcttg
    31981 tctgagaaat ttggctgggc tgatgttcaa gttttggaaa cttaccgtgg ccaagaactc
    32041 aaccacatcg taacagaaca cccatgggat acagctgtag aagagttggt aattcttggt
    32101 gaccacgtta cgactgactc tggtacaggt attgtccata cagcccctgg ttttggtgag
    32161 gacgattaca atgttggtat tgctaataat cttgaagtcg cagtgactgt tgatgaacgt
    32221 ggtatcatga tgaagaatgc tggtcctgaa tttgaaggtc aattctatga aaaggtagtt
    32281 ccaactgtta ttgaaaaact tggtaacctc cttcttgccc aagaagaaat ctctcactca
    32341 tatccatttg actggcgtac taagaaacca atcatctggc gtgcagttcc acaatggttt
    32401 gcctcagttt ctaaattccg tcaagaaatc ttggacgaaa ttgaaaaagt gaaattccac
    32461 tcagaatggg gtaaagtccg tctttacaat atgatccgtg accgtggtga ctgggttatc
    32521 tctcgtcaac gtgcttgggg tgttccactt cctatcttct acgctgaaga tggtacagct
    32581 atcatggtag ctgaaactat tgaacacgta gctcaacttt ttgaagaaca tggttcaagc
    32641 atttggtggg aacgtgatgc caaagacctc ttgccagaag gatttactca tccaggttca
    32701 ccaaacggcg agttcaaaaa agaaactgat atcatggacg tttggtttga ctcaggttca
    32761 tcatggaatg gagtggtggt aaaccgtcct gaattgactt acccagccga cctttaccta
    32821 gaaggttctg accaataccg tggttggttt aactcatcac ttatcacatc tgttgccaac
    32881 catggcgtag caccttacaa acaaatcttg tcacaaggtt ttgcccttga tggtaaaggt
    32941 gagaagatgt ctaaatctct tggaaatacc attgctccaa gcgatgttga aaaacaattc
    33001 ggtgctgaaa tcttgcgtct ctgggtaaca agtgttgact caagcaatga cgtgcgtatc
    33061 tctatggata tcttgagcca agtttctgaa acttaccgta agattcgtaa cactcttcgt
    33121 ttcttgattg ccaatacatc tgactttaac ccagctcaag atacagtcgc ttacgatgag
    33181 cttcgttcag ttgataagta catgacgatt cgctttaacc agcttgtcaa gaccattcgt
    33241 gatgcttacg caaactttga attcttgaca atctacaagg ccttggtgaa ctttatcaac
    33301 gttgacttgt cagccttcta ccttgatttt gccaaagatg ttgtttacat tgaaggtgcc
    33361 aaatcactgg aacgccgtca aatgcagact gtcttctatg acattcttgt caaaatcacc
    33421 aaactcttga ctccaatcct tcctcacact gcggaagaaa tctggtcata tcttgagttt
    33481 gaagccgaag acttcgtcca attgtcagaa ttaccagaag ttcaaacttt tgctaaccaa
    33541 gaagaaatct tggatacatg ggcagccttc atggacttcc gtggacaagc acaaaaagcc
    33601 ttggaagaag ctcgtaatgc aaaagttatc ggtaaatcac ttgaagcaca cttgacagtt
    33661 tatccaaatg aagttgtgaa aactctactc gaagcagtaa acagcaatgt agctcaactt
    33721 ttgatcgtgt ctgagttgac catcgcagaa gaaccagctc cggaagctgc ccttagcttc
    33781 gaagatgtag tcttcacagt tgaacgcgct gcaggtgaag tatgtgaccg ttgccgtcgt
    33841 attgacccaa caacagcaga acgtagctac cacgcagtca tctgtgacca ctgtgcaagt
    33901 atcgtagaag aaaactttgc agatgcagtc gcagaaggat ttgaagagaa ataagattga
    33961 aaagtctagg taaaactcaa tttgagaaga aaagacaact aattttatag tctattaaac
    34021 gcattgtatc acgtttttga acacctgata tgatgcgttt tttatttatt ttaaaaattt
    34081 gcgaggtatg actttttata ctcaacaaga atcaaagaga aacttagcaa gctaacagta
    34141 gtaatataaa ataggaattt gatattaggg ataagattgg taaatagtgt aatattttta
    34201 caacaataaa tttatatagt tatttctggt ttctgaaaag tattatatta tattttattt
    34261 catattatac aaatttttat tttataatat cagaaaatac tttttttaaa aagcaaatat
    34321 gatacaattt tatttgaaaa aaaataaaaa aggagatttt attatgaaat caagtggtat
    34381 cgtcggtctt gtgggaggaa ttttacttct tatttgtcct tttgtcttgt tgggaacagc
    34441 ggtaaataca gctgctacaa ctcttaatgg aggagctact gcaggggctt tttcaggtgt
    34501 tgccttactc ttgaatgcct tgaagattgc aaatcttgtt cttggtatca ttgctattgt
    34561 ttactataaa ggagataagc atgtaggtgc agctccgtct gtactaatga ttgtttctgg
    34621 tgaagttagt ctcattccat tcttaggatg ggttgggggg attcttgcta ttatcggagg
    34681 atctctattc cttgcaacat tgaagaaatt caaatcagaa gaataaaagg tattttagca
    34741 tgaaaagaac aaaaaagttt atcggtatag gagtagctct attatctctt tctcttctag
    34801 ttgcatgtgg aacataaagt tcaaagaata cttcaacaag taatgatgag aagacagtag
    34861 caacatccaa tagttcaaaa gaaacaatca ctttcgatac accggttgta acagacgatg
    34921 cgattgaatc aatacgcact tatgcagatt atatagatct ttataaaaat atttttgatg
    34981 attattttac taaagctgag gaaggtttca aaggcacaac tatggaaaat aatgactcgt
    35041 ttactaaact aaaagagtca actcaaaaat tattcgatgc gcagaaaaaa aggttaaata
    35101 atgaagatag aatagaaaca accaaaaaca atgtgattgc caaacattgt caaacagtcc
    35161 tttccttttt ggttttgact agcttttttg tgaaaaattg tgtaaaatag aatagataaa
    35221 cgaggggaaa cctcggaaaa tttaaaggag aatccatcta atggtaaaat tggtttttgc
    35281 tcgccacggt gagtctgaat ggaacaaagc taaccttttc actggttggg ctgatgttga
    35341 tttgtctgaa aaaggtacac aacaagcgat tgacgctggt aaattgatca aagaagctgg
    35401 tatcgaattt gaccaagctt acacttcagt attgaaacgt gctatcaaaa caactaactt
    35461 ggctcttgaa gcttctgacc aattgtgggt tccagttgaa aaatcatggc gcttgaacga
    35521 acgtcactac ggtggtttga ctggtaaaaa caaagctgaa gctgctgaac aatttggtga
    35581 tgagcaagtt cacatctggc gtcgttcata cgatgtattg cctccaaata tggaccgtga
    35641 tgatgagcac tcagctcaca cagaccgtcg ttatgcttca cttgacgact cagtcattcc
    35701 agatgctgaa aacttgaaag tgactttgga acgtgctctt ccattctggg aagataaaat
    35761 cgctccagct cttaaagatg gtaaaaacgt attcgtagga gctcacggta actcaatccg
    35821 tgcccttgta aaacacatca aaggtttgtc agatgatgag atcatggacg tggaaatccc
    35881 taacttccca ccattggtat tcgaattcga cgaaaaattg aacgttgttt ctgaatacta
    35941 ccttggaaaa taaaaaattg taagcctagg attgatttct aggcttttta tgttagtatg
    36001 gaagtatgat aaggaataaa aaacaagatt atgtactggc ctacaagcaa ccagcttcaa
    36061 ccacttacat gggttgggaa gaagaagctt taccgatagg caatggttct ttaggagcaa
    36121 aagtatttgg ccttataggg gctgaacgga ttcaatttaa tgaaaaaagt ctctggtctg
    36181 gaggtccact tcctgatagt tcagattatc agggtggaaa tcttcaggat cagtatgttt
    36241 ttttagctga gattcggcag gctttggaga agagagatta caatctggct aaggaactgg
    36301 ctgagcagca cctaattggg ccaaaaacga gtcaatatgg gacctatctg tcttttgggg
    36361 atattcacat tgagttcagc cagcaaggta cgactttgtc tcaggtgacg gactatcaga
    36421 gacagctgaa tattagtaag gcacttgcga cgacttctta tgtctataag ggaacgcgat
    36481 ttgaacgtaa agcttttgcg agttttccag atgatctctt gattcaatgt tttactaagg
    36541 aagggttgga aactctagat tttactatag aactatcctt gacctgtgat ttggcttctg
    36601 atggaaagta tgagcaggaa aaatctgatt acaaggagtg taagttggat attactgatt
    36661 ctcatatctt gatgaaggga agagttaagg ataatgatct gcggtttgct agttatctag
    36721 cttgggaaac ggatggagat attagagttt ggtcagatag ggttcagata tcaggagcca
    36781 gttatgccaa tctcttcttg gccgctaaga cggattttgc ccaaaatcct gctagcaatt
    36841 atcgcaagaa actagattta gagcaacagg tgatagactt ggtggacaca gctaaagaaa
    36901 agggctatac ccaattgaaa tcaaggcata tcgaggacta ccaagcctta ttccagcgtg
    36961 ttcaattgga tttggaagct gatgttgacg catccactac agatgatttg ttaaaaaatt
    37021 ataagccaca agaagggcag gctttggagg agctgttctt ccagtatgga cggtatttat
    37081 tgattagttc gtccagagac tgcccagatg ctctaccagc taacctacag ggagtctgga
    37141 atgcggtcga caatcctcct tggaattcgg actatcactt aaatgtcaat ctgcagatga
    37201 attattggcc agcctatgtt accaatctcc tagagacggt ctttccagtc atcaactatg
    37261 tagatgattt gcgtgtctat ggtcgtctag cggctgtaaa gtatgcagga atcgtctctc
    37321 aaaaaggtga ggaaaatggt tggttggttc atactcaagc gactcccttt ggttggacgg
    37381 cacctggttg ggattactat tggggttggt caccagctgc caatgcgtgg atgatgcaaa
    37441 ccgtttatga agcctattca ttttataggg accaagacta tctcagggag aaaatttatc
    37501 ccatgttgag ggaaacggtt cgtttttgga atgccttttt acataaggat cagcaggcgc
    37561 agcgttgggt ctcttctccg tcttattccc cagaacatgg gccgatttcg attggcaata
    37621 cctatgacca atctctgatt tggcagttat ttcatgattt tattcaggct gctcaggaat
    37681 tgggactgga tgaggacttg ttgactgagg ttaaggagaa gtctgattta ctaaatcctt
    37741 tgcaaatcac tcaatctggt cgaatcaggg agtggtatga ggaggaagag cagtattttc
    37801 aaaatgagaa agtggaggcc cagcatcggc acgcttccca tctagtggga ctctattctg
    37861 gcaatctctt tagctacaag ggacaagagt atattgaagc ggcgcgtgct atcctcaatg
    37921 atcgtggaga tggcggcaca ggctggtcca aggctaataa gatcaatctc tgggcgcgtt
    37981 tgggagatgg caatcgagcc cataaattat tggcagagca gttaaagaca tccaccttgc
    38041 caaatctttg gtgtagccat cctccttttc agatagatgg taattttggt gctactagtg
    38101 gcatggcaga aatgttactc cagtctcatg cagcttatct ggtacctcta gctgccctac
    38161 ctgatgcttg gtcaacaggt tctgtttcag gcttaatggc acgtggacat tttgaagtga
    38221 gcatgagctg ggaagataaa aaactcttac agttgaccat tttatcaagg agtggaggag
    38281 atttgcgagt ttcttatcca gatattgaga agagtgtgat taaaatgaat caagaaaaaa
    38341 taaaagcgaa atgcatgggg aaagattgta tttcggtggc aacagcagaa ggtgatcttg
    38401 ttcaatttta tttttaagaa gatgttataa ggcagtaatt tgaaacttcc ttttaataag
    38461 gatttgagaa tataggcagt ttccaactag ttgaaaaagc gttataatga taataggaag
    38521 taatactcaa tgaaaatcaa agagcacaaa ctaggaagct agccgcaggt tgctcaaaac
    38581 agtgttttga ggttgtagat ggaagctgac gtggtttgaa gagagatttt cgaggagtat
    38641 aatttgtttg atagagggtg ggtctgatgg cttatattga gatgaaacac tgttacaagc
    38701 gttatcaggt tggggacacg gagattgtgg ccaatcgtga tgtgaatttt gagattgaaa
    38761 agggggagct ggttattatc cttggtgctt caggtgcagg caagtcaaca gttcttaacc
    38821 ttcttggggg aatggatacc aatgatgaag gggaaatctg gattgatggt gttaatattg
    38881 cggattatag ttcccaccag cgtaccaatt accgtagaaa tgatgtgggg tttgtttttc
    38941 agttttataa tctagtttct aatctgacag ctaaggaaaa tgtggaactg gcttctgaaa
    39001 ttgtgacaga tgccttgaat cctgatcagg tcttgacaga tgtaggtctg gctcatcgtc
    39061 tcaataactt tccagcccag ctttctggag gggagcaaca gcgagtctcc attgcacgcg
    39121 cggtagccaa aaatcctaaa attctccttt gtgatgaacc gactggagcc ttggattatc
    39181 agacgggcaa gcaggttttg aaaattctcc aagacatgtc tcgtcaaaag ggagcgacgg
    39241 tgatcatcgt gactcataat ggagctttgg cgcccattgc tgatcgcgtg attcaaatgc
    39301 acgatgccag tgtcaaggat gtggtgctca accagcatcc tcaggatatt gacagtttgg
    39361 agtactagca tgatcaagcg aaaaacttat tggaaggact taattcagtc cttcacaggc
    39421 tccaaggggc gttttttatc catcttgatc ctgatgatgt tgggatctct agccttagta
    39481 ggcctcaaag taaccagtcc caacatggag gcgacagcta atgcttattt aacaactgct
    39541 caaaccttgg atttggcagt catgtctaac tatggcttgg atcaagcaga ccaagaagaa
    39601 ctaaaacaga cggagggcgc agaggtcgag tttggctatt tgacagatgt gactatggat
    39661 aatgggcagg atgccattcg gctgtactcc aaaccagagc gaatttcaac ctttcagcta
    39721 agaaagggac gacttcctca gtcagacaag gaaatcgctt tggccactca tttgcaaggc
    39781 caatacagcg tgggacagga gattagtttt aaagaaaaag aagagggtca ttcctcttta
    39841 aaagaccata cttataccat tactggtttt gtggattcgg ctgaaatcct ctcccagcga
    39901 gatatgggct acgcaggaag tggaagtggg actctgacag cctatggggt gattttacct
    39961 agtcagtttg atcagaaagt ctacaatata gctcgtttga aatatcaaga tttagcaggt
    40021 ttaaatgcct tttcatcagc ttatgaagaa aaatccaagc aacatcagga agaccttgaa
    40081 caaactttat cagataatgg caaggtacgt ctgcaacttt tgaaaaaaga aggacaagag
    40141 tctctagaca aggggcaaga gacccttgac aaggctcaga ctaatttgca ggaaggcaag
    40201 cgtcgtttag cagctgctca agctcgtata caggctcaag aaagtcaact agccttgttt
    40261 cctcaagttc agagagagca ggctagtgct caacttaccc aagccaagca ggaattgggc
    40321 aaggaagagg ataaactaaa gcaagctgaa caaaatctag cccaagaaaa ggaaaaatta
    40381 gaaaaacatc agcaagtctt ggacgatttg gcggagccaa ggtatcaggt ctataatcgt
    40441 cagaccatgc caggtggtca gggctatctt atgtatagca atgcttcatc cagtattcga
    40501 gcagtgggca atatctttcc tgtggtactt tatgccgtag catccatggt gacctttacg
    40561 accatgactc gctttgtaga cgaagagcga actcatgcag ggatttttaa ggccttgggt
    40621 taccgtagta aggatattat caccaagttt ctcctttatg gactagtagc tgggactgtc
    40681 ggaacggctc taggtagtat acttggtcat tatttgctag ccagtgtaat ttcaagtgtc
    40741 attacaaaag gcatggtggt gggagaaacc cagattcagt tctattggac ctatagctta
    40801 ctagctcttg tcttgagctg gttggcgagt gtgttaccag cctatctggt ggcttggagg
    40861 gaacttcatg ccgaagcagc ccagcttcta cttcctaaac ctcctgtcaa aggagctaaa
    40921 atcttattgg agcgtatcgg ttttatctgg cgtcgtctca gttttactca taaggtaaca
    40981 gcccgcaaca tctttcgtta taagcagaga atgttgatga caatctttgg tgtggcaggt
    41041 tctgtagctc tgctctttgc aggtttggga atccaatctt ctgtagcagg agttccgtct
    41101 aaacagtttc aacaaatcca acagtatcag atgcttgtct ctgaaaatcc tagtgcgacc
    41161 aatcaggaca aggtagagct agcagaagtg ttgaaagggc aggagatact agcctaccag
    41221 aaaatctatt ctaaaacgct agacaaggat ttcaaaggca aggctggtct tcaaaacatt
    41281 actcttatga tgatagagaa ggaagatttg actcccttta tccatcttca acatcatcag
    41341 caggagctga cattaaaaga tggcatcgtt attacagcta aactcgccca gctggcaggt
    41401 gtcaaggttg ggcagacttt agaaattgaa ggtaaggaac taaaggtcgc tgctattact
    41461 gagaactacg ttggtcactt tatttatatg agtcaggcta gctatgagca actttacgga
    41521 cagctacccc aagccaacac ttatctggtc tcattaaggg ataccagtgc aactagtatc
    41581 gaaagtcagg cgggcttgct tatgaatcaa tctgcggtgt ccagcgttgt ccaaaatgct
    41641 tcagccattc gactctatcg ctagctcact caatcagacc atgaccatct tggtcatcgt
    41701 atcagttcta ttagctattg tcatccttta caatctgacc aatatcaacg tagctgagag
    41761 aatccgtgaa ctctccacta tcaaggttct cggttttcat aataatgaag tcaccctcta
    41821 catttaccgt gagacgattg tgctgtccct tgtgggaatc gtacttggtc tggtagctgg
    41881 tttctattta caccaatttt tgattcaaat gatttcgcct gcgactattc tcttttatcc
    41941 gcaggtaggc tgggaagtct atgtaatccc agtggcaaca gtaagcatca ttttgacctt
    42001 gcttggtttc ttcgtcaatt attatctgag aaaggttgat atgttagaag ccctgaaatc
    42061 tgtagagtaa ggtagttatt tttagctgat tgaacttcta tttactaata ttcaaaaatc
    42121 ctctgtcaca aagagcaggg agctctttgt gacagaggat tttttctata gggctttagc
    42181 agctgcaatt gcggcttcga agtttggctc agaattgata ttatccacgt attcaacgta
    42241 gcgaatcgta ttgtcagtat cgaggacaaa gactgcgcgt gctaataggt gccattcgtt
    42301 gatcaagagg gcataatcgc gcccgaaaga atggtcaaag tagtctgaaa gcataatggc
    42361 attgtcaagg ccttcagcac cgcaccaacg tttttgagca aaaggtaggt ccattgaaac
    42421 agtcaatacg accgtgttgt ccagtccagc caattcttca ttaaaacgac gtgtttgagt
    42481 tgagcagatg cctgtatcga tagaaggaac gacactcaag acttttttct tgccatcaaa
    42541 atcagccaga gattttttag aaagatctgt tgtagtaaga gaaaaatcaa gcgccttgtc
    42601 gccgacttgt agttgtttac ctgtaaagct cacaggattt ccgagaaaag ttaccatagg
    42661 atactccaat cttttttctt ccattgtatc tgaaacagtc agaattttcc aatgatttga
    42721 ccggaaatgt gggcatagaa aaaacgccag ctcacatgag aatgacgttt ttcagaggct
    42781 tattttgcca atccttcagc aatcttgtca aggttgtatt tcatcatgct gtagtagctg
    42841 tcgccttctt taccttgttc tgcgatagag tcagtaaaga tttgtgcgta gattgggatg
    42901 tttgtgtctt gagaaacagt tttcattgga cggtcatcca cacttgattc tacaaagagt
    42961 gatggaactt ttgtttggcg aagtttttca accaaggtct tgatttgttc aggagttcct
    43021 tcttcttcag tattgatttc ccagatgtaa gcacttggga caccataggc tttagagaag
    43081 tatttgaatg ctccttcgct ggttacaatg agtttctttt cagcagggat cttattaaat
    43141 ttatccttac tttctttatc aagtttgtct aacttatcag tatattcttt gagatttttt
    43201 tcatagaatt ctttattgtt agggtctttg gcgctcaatt gtttggcgat atttttagca
    43261 aaaataatac cgttttcaag gttaagccaa gcgtgtgggt cttcttttcc tttttcattt
    43321 tgaccttcaa ggtagataac atcaacgccg tcgctgactg cgaagtagtc tttgttttca
    43381 gttttcttgg cattttctac caattttgta aaccaagcat tgccacctgt ttcaaggttg
    43441 ataccgttat agaaaatcaa atcagcctca gaagttttct taacgtcttc aggaagtggt
    43501 tcgtattcgt gtgggtcttg cccaatcgga acgatactat gaaggtcaat tttgtcacca
    43561 gcaatatttt tagtaatatc agcgatgatt gagtttgtag caacaacttt tagtttttga
    43621 ccagaagttg tatctttttt tccgctagca catgctacaa gaatgattgc agaaagaaag
    43681 agaacgagta atgtacctaa ttttttcatt agatcctcca aattattagg gctttgcccc
    43741 ttattttaac aaatgtttat ttttcagttt caaatatcgt tgtttgggag cgataaagaa
    43801 gctaatgaga aagaaactag cagctgtaag cacgatacta gaacctgccg caacattaaa
    43861 actatagcca ataaagagtc ccaaaactga agcagtagct ccgaaggttg aggaaaggaa
    43921 aatcatgctt ttcagactat tagcatacag ataagcagtt gcagctgggg taatcagcat
    43981 ggctacaatc aggatagttc cgacactttg catggctgtc acagacacga gagtcaggag
    44041 taccatgaga aggtagtgat agaaattgac aggcattccc atggctttag ccaagagttc
    44101 atcaaaggaa gttatcaaga gttgcttgaa gaaaatccag attaacaaga ggatggctgc
    44161 ccccacaccc atagtaataa acatatccgt atcttggacg gccaggatat taccaaaaag
    44221 gatatggaaa aggtcagttg aacttttagc gacaccaatc aagatgatac cgagggctaa
    44281 gaaagaagaa aaggtaatgc cgatggcggt atcgcttttg ataatcgagt ttcctttgat
    44341 gtaggtaatg atgatggcag ctagcaatcc aaagacaatg gctccgataa agaagtcaag
    44401 gcccaagatg aaggagaggg ctacacctgg taagacagca tgtgaaatgg catctcccat
    44461 gagtgacatc ccgcgtagaa taatgaaaca tcccacagct ccagctacaa tcccgacgac
    44521 aatagctgtt atcaaggcat tttgtaggaa atggaatttt tgcaatccat cgataaattc
    44581 tgcaatcata ggtcacctcc attgaaaaag agttgattac cgtaagcttc ttttagattg
    44641 gtttcggtaa aagtttcttt tgttggacca aaggcaatca cttctcgatt gacaagtaag
    44701 acttgatcga agtagtgggg aatcttgctg aggtcgtggt gaacgatgag aaccgtcttc
    44761 ccagcttttt tcaaatctct cagcgtattc atgatgattt cctcactgac agagtcaatc
    44821 ccagcaaagg gttcatccaa gaggatatag tcggcttcct gcaccaaaca tctggcaatc
    44881 aaaacccgct ggaattgacc tccagacagt tgactaattt gacgttcagc gtagtcagct
    44941 aggccgacga tttcaagggc ctcttgcact ttcttccaat gtttagcctt taaacttcga
    45001 aagagaggaa tagagggaaa tagtcctaac gagacgcatt ccttgacctt gatgggaaag
    45061 ttgtagtcga tattgatttt ttgttcgaca taggcaattc ggtgtaagga ttttttaact
    45121 tccttgtcat cgagaaatgc ctgaccttga tgtgggataa ttcccagcat accttttaat
    45181 agtgttgatt tcccagcgcc gtttggacca atgatgccgg taattgttgg tccatggagc
    45241 actagtgaaa tatccttaag tgccaacgtt tctttgtagg agacactgag gttttcgata
    45301 cgtatcataa acttgtattc ctcctgtctc ttaatataca ttaaaaaaaa aattaagtca
    45361 agttaatttt tgaaaaaatt aaaataataa ctgaaaaata ga
//
LOCUS       DAVAZT010000012        41598 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVAZT010000012 DAVAZT010000000
VERSION     DAVAZT010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41598
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.012"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(133..474)
                     /locus_tag="VQT45_000590"
     CDS             complement(133..474)
                     /locus_tag="VQT45_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET2358954.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            598..1448
                     /gene="rgg"
                     /locus_tag="VQT45_000591"
                     /pseudo
     CDS             598..1448
                     /gene="rgg"
                     /locus_tag="VQT45_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398326.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes.; frameshifted;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
     gene            1639..2886
                     /locus_tag="VQT45_000592"
     CDS             1639..2886
                     /locus_tag="VQT45_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HET2358955.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGVSIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVSVIISSLTGNDYFGKQSLPRLMMWETVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            2964..4253
                     /locus_tag="VQT45_000593"
     CDS             2964..4253
                     /locus_tag="VQT45_000593"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HET2358956.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVTLPIENALDVYIA
                     VLGEGANIKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            4244..4324
                     /locus_tag="VQT45_000594"
                     /pseudo
     CDS             4244..4324
                     /locus_tag="VQT45_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            4560..6323
                     /gene="aspS"
                     /locus_tag="VQT45_000595"
     CDS             4560..6323
                     /gene="aspS"
                     /locus_tag="VQT45_000595"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HET2358957.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVVNATLGTLRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            6301..7242
                     /locus_tag="VQT45_000596"
     CDS             6301..7242
                     /locus_tag="VQT45_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET2358958.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(7362..7442)
                     /locus_tag="VQT45_000597"
                     /pseudo
     CDS             complement(7362..7442)
                     /locus_tag="VQT45_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(7578..8564)
                     /locus_tag="VQT45_000598"
     CDS             complement(7578..8564)
                     /locus_tag="VQT45_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2358959.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(8574..9374)
                     /locus_tag="VQT45_000599"
     CDS             complement(8574..9374)
                     /locus_tag="VQT45_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HET2358960.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRIYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(9635..10477)
                     /locus_tag="VQT45_000600"
     CDS             complement(9635..10477)
                     /locus_tag="VQT45_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2358961.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(10479..11771)
                     /locus_tag="VQT45_000601"
     CDS             complement(10479..11771)
                     /locus_tag="VQT45_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2358962.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGNKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(11882..13153)
                     /locus_tag="VQT45_000602"
     CDS             complement(11882..13153)
                     /locus_tag="VQT45_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2358963.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            13703..15220
                     /gene="malQ"
                     /locus_tag="VQT45_000603"
     CDS             13703..15220
                     /gene="malQ"
                     /locus_tag="VQT45_000603"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HET2358964.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            15246..17504
                     /locus_tag="VQT45_000604"
     CDS             15246..17504
                     /locus_tag="VQT45_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HET2358965.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(18548..19120)
                     /locus_tag="VQT45_000605"
     CDS             complement(18548..19120)
                     /locus_tag="VQT45_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2358966.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAINLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(19742..20590)
                     /locus_tag="VQT45_000606"
     CDS             complement(19742..20590)
                     /locus_tag="VQT45_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET2358967.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            20735..21013
                     /locus_tag="VQT45_000607"
     CDS             20735..21013
                     /locus_tag="VQT45_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2358968.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            21015..23078
                     /locus_tag="VQT45_000608"
     CDS             21015..23078
                     /locus_tag="VQT45_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET2358969.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(23156..24412)
                     /locus_tag="VQT45_000609"
     CDS             complement(23156..24412)
                     /locus_tag="VQT45_000609"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HET2358970.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            24554..27019
                     /locus_tag="VQT45_000610"
     CDS             24554..27019
                     /locus_tag="VQT45_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET2358971.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            27084..27995
                     /locus_tag="VQT45_000611"
     CDS             27084..27995
                     /locus_tag="VQT45_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HET2358972.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCLEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVSVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            28225..28923
                     /gene="dapD"
                     /locus_tag="VQT45_000612"
     CDS             28225..28923
                     /gene="dapD"
                     /locus_tag="VQT45_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HET2358973.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVCVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            28991..30121
                     /locus_tag="VQT45_000613"
     CDS             28991..30121
                     /locus_tag="VQT45_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HET2358974.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFTSQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            30133..30672
                     /locus_tag="VQT45_000614"
     CDS             30133..30672
                     /locus_tag="VQT45_000614"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HET2358975.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLTPKTYPKGRMDFVVYDPQQLVKTSFALLEPQ
                     GDLEVVDASQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGRALSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            30656..31333
                     /locus_tag="VQT45_000615"
     CDS             30656..31333
                     /locus_tag="VQT45_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HET2358976.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(31405..32304)
                     /gene="galU"
                     /locus_tag="VQT45_000616"
     CDS             complement(31405..32304)
                     /gene="galU"
                     /locus_tag="VQT45_000616"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HET2358977.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFNGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(32326..33342)
                     /locus_tag="VQT45_000617"
     CDS             complement(32326..33342)
                     /locus_tag="VQT45_000617"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HET2358978.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     YHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKAI
                     IMHASKGLEPDSHKRLSTILEEEIPEQLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            33554..33931
                     /locus_tag="VQT45_000618"
                     /pseudo
     CDS             33554..33931
                     /locus_tag="VQT45_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(34111..34536)
                     /locus_tag="VQT45_000619"
     CDS             complement(34111..34536)
                     /locus_tag="VQT45_000619"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2358979.1"
                     /translation="MNNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKSLTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(34604..35254)
                     /gene="phoU"
                     /locus_tag="VQT45_000620"
     CDS             complement(34604..35254)
                     /gene="phoU"
                     /locus_tag="VQT45_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET2358980.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(35269..36021)
                     /gene="pstB"
                     /locus_tag="VQT45_000621"
     CDS             complement(35269..36021)
                     /gene="pstB"
                     /locus_tag="VQT45_000621"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET2358981.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDVLLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(36023..36838)
                     /gene="pstA"
                     /locus_tag="VQT45_000622"
     CDS             complement(36023..36838)
                     /gene="pstA"
                     /locus_tag="VQT45_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET2358982.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(36831..37694)
                     /gene="pstC"
                     /locus_tag="VQT45_000623"
     CDS             complement(36831..37694)
                     /gene="pstC"
                     /locus_tag="VQT45_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET2358983.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRTFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(37812..38687)
                     /locus_tag="VQT45_000624"
     CDS             complement(37812..38687)
                     /locus_tag="VQT45_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HET2358984.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(38854..40185)
                     /locus_tag="VQT45_000625"
     CDS             complement(38854..40185)
                     /locus_tag="VQT45_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HET2358985.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSALKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(40186..40893)
                     /locus_tag="VQT45_000626"
     CDS             complement(40186..40893)
                     /locus_tag="VQT45_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2358986.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(40977..41462)
                     /locus_tag="VQT45_000627"
     CDS             complement(40977..41462)
                     /locus_tag="VQT45_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HET2358987.1"
                     /translation="MAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDYALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            41448..41598
                     /locus_tag="VQT45_000628"
                     /pseudo
     CDS             41448..41598
                     /locus_tag="VQT45_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT        12131 a         7912 c         8949 g        12606 t
ORIGIN      
        1 atccataact tcaaaacagt gttttgagca acctgcggct agttttctag tttgcccttt
       61 gattttcatt gagtatcaaa aagcaagcca ttttcggctt gcttttttca tctttaaaag
      121 tgattggtct gcttaacgag gtggtagtcc aagggcaata cggccatagc gactgattcg
      181 tgtgattttc caagcaggcg accaggtaac ttcaaccttg atatctttga taccctcgat
      241 ttgtttcaga cctgccacga tttcaatagg caggctttcg gcgcaatcac aggcagtatc
      301 ggtgaaggtc atgacaatct tgcagagccc cgtttcatcc agattgattt cataaatcag
      361 acctagattg taaacatcca attccacatc tgtatcaaaa actttctcta gtttttcgat
      421 aatttggtct tgcaaggcca aagcacggtc attgattttg atatcgtctc tcatagcagt
      481 ccctccacgt gataaatatc ctctattttc tcataattct gacaatttgg caagtttttg
      541 atgaattttc tgaaaaatat gataaaatga agaaaatacg gaatcaaggg gaagtctatg
      601 gagcagattg gaaaagtctt tagacaatta cgagagtcaa gaaatatctc actgagacaa
      661 gcaaccggag gacaattttc gccgtctatg ttgtcccgtt ttgaaacagg tcagagtgag
      721 ctttcggtgg aaaagtttct atttgctctg gaaaatatat ctgccagtgt ggaggagatc
      781 ctctttctgg caagaggttt ccagtatgat acagattctg agttgagaaa agaaattaca
      841 gatgtcttgg aaccaaagaa tatagcacct cttgaggact tatatcgcag ggagtataaa
      901 agcatgccca ttctcacaac aaacagaaac atattctaaa tgccattatt atcaagtctt
      961 atatgaagag catagatgaa agggtagact taacagcaga ggaaggaaaa gtccttcatg
     1021 attatttgtt ttctaccgag atctggggaa tctatgaact caatttattt tcagtcagtt
     1081 ctccattttt atctgtttct ctttttacta gatatgtacg agaaatggta cgtaaatccg
     1141 attttctaat ggaaatgtct ggcaatcgaa acctttttca tactatacta ttgaatggct
     1201 ttttagctag tattgagtgt gaagaattta ccaatgccta ttattttaaa cgtgttatcg
     1261 aagagcattt ctacaaggaa aatgagacct atttccgaat tgtttatctg tgggcagaag
     1321 gtctccttga tagcaagcaa ggtagagtca aggaaggcca gaaaaagatg gaggatgctg
     1381 tccgtatttt tgagatgctt ggctgtaata aatctgccga atactataga aaaactcccg
     1441 attcttgaat atctgcaaac caagaaaaaa tttgaagcga tagaactgtt gccctctctc
     1501 aggtcattac aaaagttcta tcgttttttt gctcattttg tttgttgcat atattcaaaa
     1561 gaatcgtttc gcaaattcat aagtgctata ctaaagctat tcttgatgta gaacttagaa
     1621 caaggaggga gattatctat gaaactattg tttagaaatc cagcttatag aattttgact
     1681 ttatcacgct tcttcaatgc ttttggtgtt tcgattttca acctggtctt tatcgtctat
     1741 gcatcgacct tgtcacaagc atcttttgct gttgctatgg cgaatattgt catgattctt
     1801 ccgaccctct ttacagtttt tgcagggatt cgggcagatt acacgaggga caaggtcaaa
     1861 tggatggtct atagcggttt gtttcaggcg gttctatttt ttctagcagc cctagttgtt
     1921 cagcaagcta gtctctttgc cttttctagc ctgtgtttga tcaatgtcat tagtgatatc
     1981 atcagtgatt ttgcaggtgg cctgcgtatg cctcttatta aggaaaaagt agctgaagat
     2041 gatctgatgg aggcttattc tttttcacag ttcatcacct atatttcagc tattggtggt
     2101 caagctttcg gagtctggct cttagctcta tcggtcaaca atttttctct cgttgcggga
     2161 atcaatgcct gctttttcct agtatcagcc actatcctct ttttaggaaa aagcaaattg
     2221 agcctgtcaa tgtcatctgc tgatggtgaa aacttaaaaa atgagaagct ttctatcaaa
     2281 gaccagttcc taacaattta ccgaaattta cgtctcgttt ttcttaaaag tggacagaaa
     2341 aactttggtt ttatgctctt tgctgtcttg cttattaatt ccttgggtgg cgctttgggt
     2401 ggaatttata atatcttctt tttgagccat tctctcttga atttttctta tacagaggca
     2461 ctatttatca atcaattctg tgttttagta tcagtcatca tcagtagcct tacgggcaat
     2521 gattattttg ggaagcagtc cttgcctaga ttgatgatgt gggagaccgt aggacttagt
     2581 ctagttggtt tggctaattt attcaatcaa gtcgtgcttg gtttgctatt tctcttcttt
     2641 actctgtatg tgtctggtaa agttcaacca aagattagtg ccatgctcat gaaaaatcta
     2701 gctccagagg ttctagctcg tactagtaat tttttaggtc tattgtttac cttatccata
     2761 cctgtgggaa cagcttgttt ttcactagta gccgtatgga atatacagtt gacttggatg
     2821 ctatttgttg gtctttcctt gctagctatt tttttgacaa ttcttaatct caaaaatgat
     2881 atctaaatcc taattttttt cttactgttt taatccctct atttatggta aaataagact
     2941 attaagttta aagaggattc cctatgaaat tacaaaaacc aaaaggaacg caggatattt
     3001 tacctgctga gtctgctaag tggcagtacg ttgagggctt tgcccgtgag attttcaaac
     3061 gctacaacta tgcagaagtg cgcacgccta tttttgagca ttacgaggtt atcagtcgct
     3121 ctgtcggaga tacaacggat atcgtaacca aggaaatgta cgatttttat gacaagggtg
     3181 accgtcatat taccctccgt ccagaaggaa ctgcacccgt tgtccgttcc tatgtggaaa
     3241 ataaactttt cgccccagaa gtgcaaaagc caagcaagtt ctactacatg ggacctatgt
     3301 tccgttatga gcgtccacag gcagggcgct tgcgccaatt ccaccagatt ggtgttgagt
     3361 gttttggctc tagcaatcca gctaccgatg tggaaacaat cgctatggca gcccattttt
     3421 tgaaggaaat cggtattcaa ggtgtcaaat tgcacctcaa cactcttgga aatcctgaga
     3481 gccgtgcagc ctaccgccaa gccttgattg actatttgac accgctcaag gagaccttgt
     3541 ctaaggatag ccaacgtcgc ttggaggaaa atcctcttcg tgtcttggac tctaaggaaa
     3601 aagaagacaa ggtggcagta gagaatgcgc cgtctatctt ggactttctt gatgaagaaa
     3661 gccaagctca ttttgatgct gtgcgtcaga tgttggaaaa tcttggagta gattacatca
     3721 tcgataccaa tatggtgcgt ggtctggact actacaacca caccattttc gagtttatca
     3781 cagagattga gggcaatgac ctgaccgtct gtgcgggtgg tcgctacgat ggtttggttg
     3841 cttactttgg aggccctgaa actgctggat ttggttttgg acttggtgta gagcgcctgc
     3901 ttctcatcct tgaaaagcaa ggtgtgaccc tccctatcga aaacgcccta gatgtctata
     3961 tcgcagtctt gggcgaaggg gcaaatatca aggccttgga attggtacag gctcttcgcc
     4021 aacaaggttt caaagcagag cgtgattacc tcaaccgtaa actaaaagct cagttcaagt
     4081 cagccgatgt ctttgcggct aagaccctca tcaccctagg agagagcgaa gtcgaaagcg
     4141 gacaagtgac ggtcaagaac aaccaaaccc gagaagaagt gcaagtgtca cttgagacaa
     4201 tcagccaaaa cttctcagaa atctttgaaa aactaggatt ttatactcaa taaaaatcaa
     4261 agagcaaact aggaagctag ccgcaggttg ctcaaaacac tgttttgagg ttgtggatag
     4321 aactgacgaa gtcagctcaa aacatggttt tgaggttgta gatgaaactg acgaagtcag
     4381 taacaatacc tacggtaagg cgacgctgac gtggtttgaa gagattttcg aagagtatta
     4441 gcgctaattt ttagggcttt cacctgactt ttaaagactg gcaaactttt ctgatgattt
     4501 tcatgaagag cctgcgcttt tatggtaaaa tagtaacaga ataaaagagg agagaaataa
     4561 tgaaacgtag tatgtatgct ggtcgtgttc gtgaggaaca catcggacaa gaaataacct
     4621 tgaaaggatg ggttggccgt cgtcgtgacc ttggtggttt gatctttatc gatcttcgtg
     4681 accgtgaagg aatcatgcag ttggttatca accctgaaaa agtatctgca gaggttatgg
     4741 caacagctga aagccttcgt agcgaatttg ttattgaggt gactggtcag gtcgctgcgc
     4801 gtgagcaagc caatgataag ttgccaactg gtgcggttga gttaaacgtg acagctctta
     4861 ttgtgcttaa cacagctaag acaacaccat ttgagattaa ggatggcatt gaggcaaatg
     4921 acgatacacg tttgcgttac cgttaccttg accttcgtcg tccagaaatg ttggaaaatc
     4981 ttaaacttcg tgccaaggtg acccactcta tccgcaacta tttggatgag ttggagttta
     5041 tcgacgtgga gacaccattc ctttctaagt caacgcctga aggggcgcgt gattatttag
     5101 tgccgtctcg tgttaataag gggcattttt acgctcttcc tcaaagtcca caaatcacga
     5161 aacagctctt gatgaatgct ggttttgacc gttactacca aatcgttaaa tgtttccgtg
     5221 acgaggactt gcgtggagac cgccagcctg aatttactca ggtcgacttg gaaacgtcct
     5281 tccttactga gaaagaaatc caagatatta cagaaggctt gatcgcgcgc gtgatgaagg
     5341 aaacaaaagg catcgaagta acgctaccgt tccctcgtat gaaatacgat gatgctatgg
     5401 ctctttacgg ttctgacaag ccagatactc gttttgacat gttgcttcag gacttgacag
     5461 aagtggtcaa aggtgtagac tttaaagtct tttcagaagc acctgctgta aaagcgattg
     5521 tggtcaaagg agctgcggac aactattcac gtaaagacat cgacaagatg acggaagtag
     5581 ccaaacagta tggtgccaaa ggtcttgctt gggtcaaggt ggttgatgga gaattaaacg
     5641 gaccagttgc caagttcttg actggtatcc aagaagaatt gacaacagcg cttgctcttg
     5701 aagataagga cttggttctc tttgtggcgg atacgcttga agtggttaat gcaacactgg
     5761 gtacccttcg tggacgtatt gctaaagagc ttggcttgat tgataatgat aagttcaact
     5821 tcctttgggt ggttgactgg ccgatgtttg aatggtctga agaagaaggc cgctacatga
     5881 gcgcccacca tccattcaca cttccacagg aagagactgc tcacgaatta gaaggtgatt
     5941 tggctaaggt tcgtgccatt gcttacgata tcgtcttgaa cggttatgag cttggtggtg
     6001 gtagccttcg tatcaaccaa aaagaccttc aagaacgcat gttcaaggct cttggtttct
     6061 caactgaaga agccaatgac cagtttggtt tccttcttga agccatggac tatggtttcc
     6121 caccgcacgg tggtttggct atcgggcttg accgttttgt catgttgctt gctggagaag
     6181 aaaatatccg tgaagtcatt gcctttccta agaacaacaa ggcaactgac ccaatgacac
     6241 aagctccatc aacagtcgct ctcaaacaac tagaggaact cagcttacaa gtagaagaag
     6301 atgaaacaaa caaaacgaat taagcggtgg cgctattatc tgcgccgctt tgcttatcag
     6361 ataaaaattt tacgtgtctt acaaagtatc tctcgagaaa agtatgatga gaagatttcg
     6421 gcctctctgg tctatggttt tttatcagca gtagcagtta atttcttttt ccaaccaggg
     6481 catgtgtatt cgagtggtgc aacaggtctg gcacagatta tctctgcctt gagtaatcac
     6541 tggtttggtt ttcatattcc gatttcgcta agcttctacg ccattaactt ccctttgatg
     6601 gtcttagctt ggtatcagat tggccataag ttcaccgtct ttacctttat cacggtatct
     6661 atgagttcct tctttatcca gtttgtccct gtggcaacct tgacggagga tcccattatc
     6721 aattcccttt ttgggggtgt tgttatgggt ttggggattg gttttgctct tcgaaacaat
     6781 atctccagtg gtgggacgga tatcgtcagc ctgactattc gtaagaaaac gggtaagaat
     6841 gtcggtagta tttctttctt ggtaaatgga actatcatgc tgatagcagg tttgaccttt
     6901 ggttggaaat acgctcttta ttctatgatt accatctttg tctctagccg tgtgacagac
     6961 gcagtcttta ctaagcaaaa gcgtatgcag gccatgattg tgacaaatca tccagagaag
     7021 gtaattgaaa aaatccataa aaaattgcac cgcggagcaa ccatgatcca cgatgcagaa
     7081 ggaacctata atcacgagag aaaggcagtt ttaatcactg tcattacacg tgcagagttt
     7141 aatgaattta aacagattat gacacaagtg gatccaagct cctttgtctc tgtctcggaa
     7201 aatgttcata ttctaggaag atttgttgag atagataatt agtgattaat actcttcgaa
     7261 aatctcttca aaccacgtca gcttcacctt gccgtatata tgttactgac ttcgtcagtt
     7321 ctatctgcaa cctcaaaacc atgttttgag ctgacttcgt cagtttcatc tacaacctca
     7381 aaaccatgtt ttgagcaacc tgcggctagc ttcctagttt gcactttgat tttcattgag
     7441 tataaaaaga tcttgggaaa agactcaatt tcagtagaaa aggaagtaaa tcttcccaca
     7501 ttaaaacgca tagtatcaag ttttttcaat acctgatagt atgcgttttt gcttttaacg
     7561 actttttgcc cagtctctta tttttcgata attttgtggg cgatcaattg acggtaacaa
     7621 atttgtttat tgtttttatt atcattaata atctggagaa tagtttcaag ggaaacacga
     7681 ccaagctcta aactattgat atcgacatag gctgccaagt tgagcttggg attaaccgag
     7741 tcaaagctga gaacagggac atccagctgg tgtttggcaa tatagttaca aacgccttca
     7801 gctaggaggc tatcggttgt gatgatagca tcaatttgtg gatcgtgctt gaataatcgc
     7861 ttgctaaatt tatagccctt ttcttccaga aactcgtcgg caaagtagat gcgattgttg
     7921 tcagtggtaa gtttgtaatg tttaagcgcc tgttcatagc ctgttaaacg gtctttggtc
     7981 acgaagagct ttttacttcc tccgataaag gcaatgcgtt tgcagccttt tttgatgaaa
     8041 tattcagtcg catcaaaacc agcttgaaca ttgtcgttgt cgacaagtgg gatgaaagga
     8101 gatagagatt tacctaagat aaggaagggg aactgttctt ctgcgacgag ttttacgaga
     8161 gggtcttctt cttgggcata gagaaagatt agcccatcta cacgcttgcc gtagaccatt
     8221 tgtgaaatag cgttgagacg ctccttctca tctttccctg ttgctatctg aatggcatag
     8281 tggttttcag atgcgacttg agagatgcca cgtagaaccg atggaaagaa aggattctgg
     8341 tagaaggcgt ctgagtcatc aggaagaact aatccgataa cctgagtata gctgcttacc
     8401 aagctacgag cgttgaggtt tgggtggtag ttgagttcct tcatagcttt gcgaacgcgt
     8461 ttttttgttt cgtcgctaat ggttgattta ttttgaataa cacgggttac ggttgaaggc
     8521 gaaacaccag cagccttggc cacgtcttta atcgtaacgg gcataaaaat ctcctattta
     8581 tggtaatttg gatcacggaa atgtgtttta taaaagatag tgaccagata cagaacaaaa
     8641 agaatatttt gtacagtaat cagggttgtc atattttggc caaataatcc caaaataagt
     8701 gtaatcagag tcggcaatcc taaacagttc aagataaagt gatagcactc tttaaaggtt
     8761 ctaaatgaaa agaggcgtga tttcttagtg atataaagga gaagactagc tcctagagag
     8821 acgataaaga aattcaaacc aaagaggaag ctcgcaccga gaactaggaa gaggctgata
     8881 tagatacgat tttgttggta ccagtcttta gaaattgctt gggtcaagct gtctttgctt
     8941 ttgaaactct cagtctgaat ggctcggtaa gagatgcggg tcagttcctt gctttccttg
     9001 ctgatgacta gttcatttgt atcgaaatgc agttgcaagt ccttaggtaa ttccttgatt
     9061 tgacttggac caatcacaac agaaggggct tgactagctg ttccagtata agttaatgtg
     9121 ccatcgacaa ttgtagcatg ttcagagaga tcctggacaa cctcatttgt cagaggttca
     9181 tagacattat cgataaaagt ttctagcgga taggtctcct gggagctgtt ttggatagca
     9241 atgggtacca tagacaagct gataaggaag atactggtaa agagaagttg aaaccagttg
     9301 agctcgaaac gtttggacag gggcttacga aacccccaaa tacttgaaaa ataggaaaat
     9361 ggatatggaa gcataggtat ctttctaaaa ggtgttttct atatgagtat tattatatag
     9421 agaaatgcgc tttatttcaa gtctaggaga aaaattgctt gctacaagga tattatttac
     9481 agtgacaatt gctaataatc aatgaaaatc aaagtgcaaa ccaggaagct agctgcaggt
     9541 tgctcaaagc acaactttga ggttggagat aaagctgacg tggtttgaag agattttcga
     9601 agagtataaa atgaaaaagg gtggcgggga taaattatcc cttgtcgcca ccacttgtaa
     9661 gtcctgaaac aaagttcttt tgtagaaaga agaagagaat acagattgga agggcgatga
     9721 ggatagcacc tgctgagaag taggcaatct tcaagttttt cgcattgtta acgaaggttt
     9781 ggagacctac ggcaacagta aagtattctt tctcacgaag caagaaacta gagaggatgt
     9841 agtccccgaa aggtcccatg aaggcccaga gagcttgtac ggcaaccatt gggcgaacaa
     9901 gtggtagaac aatttgccag aagcggcgga agtgtcctgc accgtctagt tttgcagatt
     9961 cgtctaaaga cattggcact gtatcgaagt agcctttcat gagccaagca ttcatcggga
    10021 taccaccacc aacgtagagg aagatgagga accagttgtg gttaagggcg ttcaacataa
    10081 gcgccataac gaagaaggct gtcaaagcgg ccatagttgg caccatttgg atgatcaaga
    10141 agaagaccaa actttgttta cgagccaaga agttgtaacg gctgtaagca taaccagcaa
    10201 gtacgatgat acttgtttga acagccatgg taattaaggc gataatcaaa gtgttgaggt
    10261 accaagtacc gtacaaggtt tcagtgaaga ggcctttaaa gttatcaaaa ttgaggtcga
    10321 tattagtatc tagtttaaag gctgagacgt tacctgcttt aaaggctgac ataatggtaa
    10381 tcaacagtgg atagataatt acaattgata gaccaatcag gtaaaggtaa gtaaggcttt
    10441 gagtcagtct acgtttgagt ttaattgagt tattcatctt agacgtcctc catatcaaat
    10501 gcgtgtagtt tcttgaatgc gatcatagag attgagatga caatgataga gataatcaag
    10561 gtaacagctg ccgccattga gtattgagga gatgtacctg ttgtcaaacg gtagatccat
    10621 gagatcaaga tatcggttga accagctcca cctccgacac taccaggtcc tccaccattg
    10681 aagaggtaca tgatagagaa gttgttaaag ttgaaggtgt attggctaat caaagtaggt
    10741 gccgcaacag ccaaaatcat tgggaaagtg atgttgcgga atttttgcca agcgttggca
    10801 ccgtcaatat aagctgcttc gtaaaggtcg ttaggaatag attgcaagat acccaaagtc
    10861 aaaacgtaga tgtatgggaa tccgagccaa ccttgcatca taatcaaggc aatcttagtc
    10921 caagttgggt ctgttttcca aggaataaga gctccatcaa ggaaaggaag gaatttagcc
    10981 aagattggca atacttgagt gttgatagca ccgacactat cgttaaacat gtttgagaat
    11041 gtcaagatag tgatgaaggc tgggacagcc caaggaagaa ggaaaataac accaaagata
    11101 cgttttcctt tgataaatgg ttggttggca atgatagctg tgaagatacc aattacgatt
    11161 tgtaaagtag aagctgccaa agcccaaatg atagtccaag aaagaacaga accaaaggca
    11221 gaacggaagg tactcaagct ccaaatgttt gtaaagttgg tcaaaccaac ccagtccaac
    11281 aacttgtttg gtggcaagtg ttggaagtcg tagttggtaa aggcgatcat caaggttacg
    11341 ataactggga agataatcgc gaaggtcatg gcaacataag atggaatgat caagaggtaa
    11401 gggaagccat tttcataaat ccctttgatc atgtctttga gtgtgcgtgg aactggaatt
    11461 ccattgttaa tgcgttttgc aatcgtatgt gcatctttga tatttgagaa ataaaagagt
    11521 acataaacga ttacaaagat tagatggaag gcaccacgaa tcagcataaa gagggaatta
    11581 tcacgacctg gtttgttacc aagagtgatg aggttgctca attcaggggt tgcaagtgct
    11641 aggaagtaaa ggacaaatac gatggttaca ccaaggaaga taaaaccttt ggctttttgt
    11701 ttattgtaaa tctgtcctaa cccaggaatg atagacagca gggctgcttt actaggttgt
    11761 tgcttttcca tattaactcc tttcatagga tactactttt ttataagaaa gctaaattat
    11821 ttgtgtctct attgataaat tcaaaggggg atttgatttc cacccccctt gaacaaattt
    11881 tttattcacc aaatttttgt ttgattgttt ctttgatcaa tgttacagca tcgttagcag
    11941 ctgttttagc atctttttga ccacttacag catcaaagag catatttttc gctggatccc
    12001 aaactgcaga catttgagag atgtttggca gtggttgagt gttcttgaac tgtttgataa
    12061 cagctgttgt caactcatcg tttttacctt cagcgtatga acgagcctca gtattagctg
    12121 ggatttcgtt agtcttatca tataatactt tttgttgttc agttgcaaca aggaagtcta
    12181 caaatttttg agaagcttca aggttcttaa cggcttgagg aatgacccaa gctttaccac
    12241 caccgaatgc agcatattct tttccatttg gaagagttgg gatagttgca actccgtagt
    12301 ttactttagc atctttaaag gcttgagctt tccaaggtcc gtcgatgata gcagctgttt
    12361 taccttcttg gaattgagtt tggattaagt ttccagcacc ttctgtatct tgcatacctt
    12421 taggccattt ttcgtaccaa gatttagcgt aattgatacc tacgatagaa ccgtcgtttg
    12481 caagaccgat gtctttagcg tctttaccgt tttggccaaa gacgtaagca ccgttaccgg
    12541 caagaagtcc atatgtatag tagaagtttg tccagtcagc taggaaggca gtagttttac
    12601 catcttcacc agcgaatgcg tatttgctat ctttagcaag gttttccaag tcagcaaatg
    12661 tttttggagc atctttcacc aagtctttgt tgtagtacat aacaagtgac tcgataacgg
    12721 caggagcacc gtaaacttta ccattagcag ctgttacaag agatttagtt gtgtcgtctg
    12781 ttttagcacc atcgctcaat ttcacttctg aaagttgtcc gtcagaacca aggctaccta
    12841 cacggtcgta tggagccatc ataacatcag ggacattacc agattggttg tcaagagaaa
    12901 gtttatcaag acctcctaga gcatcaccag ttttaagagt gacttttact ccagcttctt
    12961 tttcataagc tttagcaacc tcttcaatat agctcttata tccctcgtct acatatacag
    13021 tgagttcttt gacttcagat gaaccagaat cagcaggctt atcagcagtt ttgcttccgc
    13081 aagctaccaa aagcaagcta gcaagtgtag cagttccaag caccgcagtg ctcttcataa
    13141 atttagatga catagtgtat tcctcctaaa gaatagcaag ttttattgat aaggaaacgc
    13201 aaacgttttc ctttatgagc ttagtatagc acaaatagaa aacggttgca agtatttttt
    13261 gtaaaaattt taaaaaattt ttaagcttga tttgatagca taattttgca ttttaataga
    13321 agaaaagtat gaaatagata agaatacagt atttttaata aaaatatatg gaatctgtct
    13381 aaagagggaa atcaggaggg gctacctccc tgtttctaat ctatatctat tttctataga
    13441 cgtttgtgct ttgttacata taaattcaag ctccctaagg aggttttata ctttgtagac
    13501 tgtctcgtga gagtcaaacc ttaggattag atagttttaa gttatctttg ctaaaatgag
    13561 ttagtttcct taaaaataat caaaaaagtt ttttaaaaac gcttgcaatt atgcttgaaa
    13621 aggagtatac ttataagtaa cgcaaacgtt tgcgtctgca aaatacgcaa cgttccatta
    13681 ttttaacaca cgaggtgcta ttatgaaaaa acgtcaaagt ggtgtgttga tgcacatctc
    13741 ttctcttcca ggagcttacg gaatcggatc atttggtcaa agtgcttacg acttcgttga
    13801 tttcttggtc cgtacaaaac aacgttactg gcaaatcctt ccattaggag caactagtta
    13861 cggggattct ccttaccaat ctttctcagc cttcgcagga aacactcatt ttatcgattt
    13921 agatatcttg gtggagcaag gtttgttgga agcaagtgac cttgaaggag ttgactttgg
    13981 tagcgatgcg tctgaagttg actatgctaa aatctactat gcacgtcgtc ctcttttaga
    14041 aaaagcggtg aaacgtttct ttgaagtcgg agatgttaaa gattttgaga aatttgctca
    14101 agacaaccaa tcatggcttg agctctttgc tgagtatatg gctatcaaag agtattttga
    14161 caatcttgct tggactgaat ggccagatgc agatgctcgt gctcgtaaag cttcagcact
    14221 tgaaagctat cgtgagcaat tggcagacaa gttggtttac caccgtgtga ctcaatactt
    14281 cttcttccaa caatggttga aattgaaagc ttacgctaac gacaaccaca tcgaaatcgt
    14341 tggggacatg ccaatctacg tagcggaaga ttcaagtgat atgtgggcaa atccacatct
    14401 cttcaaaaca gatgtcaatg gtaaggctac ttgtatcgca ggatgcccac cagatgagtt
    14461 ttctgtaact ggtcagcttt ggggtaaccc aatctatgac tgggaagcaa tggacaaaga
    14521 cggctacaaa tggtggattg aacgcttgcg tgaaagcttc aaaatctacg atatcgttcg
    14581 tatcgaccac ttccgtggct tcgaatctta ctgggaaatc cctgctggtt ccgatacagc
    14641 agcacctggt gagtgggtga aaggtccagg ctacaagctt tttgcagccg ttaaggaaga
    14701 acttggtgag ctaaacatca tcgcagaaga ccttggcttc atgacagatg aagtgatcga
    14761 attgcgtgaa cgtactggct tcccaggaat gaagattctt caatttgcct tcaacccaga
    14821 agacgaaagc attgatagcc cacacttggc acctgctaac tcagttatgt acacaggaac
    14881 acacgataac aatacggttc ttggttggta ccgtaatgag attgatgatg cgactcgtga
    14941 gtacatggct cgttacacga accgtaaaga atacgaaaca gtggtacacg ctatgcttcg
    15001 tacagtattt tcatcagtta gctttatggc aattgcaact atgcaagatt tactagaatt
    15061 ggatgaggca gctcgtatga acttcccatc tacccttggt ggaaactggt cttggcgtat
    15121 gactgaagat caattgacac cagctgtcga ggaaggtttg cttgacttga caacaattta
    15181 tcgccgaatt aatgaaaatt tggtagattt aaagaaataa gacaataatc aggagacaac
    15241 taaacatgtt atcactacaa gaatttgtac aaaatcgtta caataaaacc attgcagaat
    15301 gtagcaatga agagctttac cttgctcttc ttaactacag caagcttgca agcagccaaa
    15361 aaccagtcaa cactggtaag aaaaaagttt actacatctc agctgagttc ttgattggta
    15421 aactcttgtc aaacaacttg attaaccttg gtctttacga cgatgttaaa aaagaacttg
    15481 cagctgcagg taaagacttg atcgaagttg aagaagttga attggaacca tctcttggta
    15541 atggtggttt gggacgtttg gctgcctgct ttatcgactc aattgctact cttggtttga
    15601 atggtgacgg tgttggtctt aactaccact ttggtctttt ccaacaagtt cttaaaaaca
    15661 accaacaaga aacaattcca aatgcatggt tgacagagca aaactggttg gttcgctcaa
    15721 gccgtagcta ccaagtacca tttgcagact ttactttgac atcaactctt tacgatattg
    15781 atgttactgg ttatgaaaca gcgactaaaa accgcttgcg tttgtttgac ttggattcag
    15841 ttgattcttc tattattaaa gatggtatca actttgacaa gacagatatc gctcgcaact
    15901 taactctctt cctttaccca gatgatagtg accgtcaagg tgaattgctc cgtatcttcc
    15961 aacaatactt catggtttca aacggtgcgc aattgatcat cgacgaagca atcgaaaaag
    16021 gaagcaactt gcatgacctt gctgactacg cagttgtcca aatcaacgat actcacccat
    16081 caatggtgat tcctgaattg attcgtcttt tgactgcacg tggtatcgat cttgacgaag
    16141 caatctcaat tgttcgtagc atgactgcct acactaacca cacaatcctt gctgaagcgc
    16201 ttgaaaaatg gcctcttgaa ttcttgcaag aagtggttcc tcacttggta ccaatcatcg
    16261 aagaattgga ccgtcgtgtg aaggcagagt acaaagatcc agctgttcaa atcatcgatg
    16321 agagcggacg tgttcacatg gctcacatgg atatccacta cggatacagt gttaacgggg
    16381 ttgcagcact ccatactgaa atcttgaaaa attctgagtt gaaagccttc tacgaccttt
    16441 acccagaaaa gttcaacaac aaaacaaacg gtatcacttt ccgtcgttgg cttatgcatg
    16501 ctaacccaag attgtctcac tacttggatg agattcttgg agatggttgg caccatgaag
    16561 cagatgagct tgaaaaactg ttgtcttatg aagacaaagc agctgtcaaa gaaaaattgg
    16621 aaagcatcaa ggctcacaac aaacgtaaat tggctcgtca cttgaaagaa caccaaggtg
    16681 tggaaatcaa tccaaattct atctttgata tccaaatcaa acgtcttcac gagtacaaac
    16741 gccaacaaat gaacgctttg tacgtgatcc acaaatacct tgacatcaaa gctggtaaca
    16801 tccctgctcg tccaatcaca atcttctttg gtggtaaagc agctccagcc tacacaatcg
    16861 ctcaagatat cattcacttg atcctttgca tgtcagaagt tattgctaac gatccagcag
    16921 tagctccaca cttgcaagta gttatggttg aaaactacaa cgttactgca gcaagcttcc
    16981 ttatcccagc atgtgatatc tcagaacaaa tctcacttgc ttctaaagaa gcttcaggta
    17041 ctggtaacat gaaattcatg ttgaacggag ctttgacact tggtactatg gacggtgcta
    17101 acgtggaaat cgctgagttg gttggagaag aaaacatcta catcttcggt gaagattcag
    17161 aaactgttat cgacctttac gcaaaagcag cttacaaatc aagcgaattc tacgctcgtg
    17221 aagctatcaa accattggtt gacttcatcg ttagtgatgc agttcttgca gctggaaaca
    17281 aagagcgctt ggaacgtctt tacaatgaat tgatcaacaa agactggttc atgactcttc
    17341 ttgacttgga agactacatc aaagtcaaag agcaaatgct tgctgactac gaagaccgtg
    17401 acgcatggtt ggataaagtc atcgttaaca tttctaaagc aggattcttc tcatctgacc
    17461 gtacaatcgc tcagtataac gaagacatct ggcacttgaa ctaatactct tcgaaaatct
    17521 cttcaaacca cgtcagcttt atctgcaacc tcaaagcggt gctttgagca acctgcggtt
    17581 agcttcctag tttactcttt gattttcatt gagtataaga tacaaattta tactaataca
    17641 tcttgtaaaa aagcgagttt cgattgaaat tcgctttttt aatgatgtag atttgggtca
    17701 atcttgtcta aaaataggga aatcctagat acagtgaagg ctttaaatgc tggtttttac
    17761 tgtcctcagc cttatatttt ttcgtagttg attacctcat acctcttgta ttcgcttaca
    17821 taaagtatta taatataatt gtaggaaaga aggtgttttt atgatataca cacttaaatt
    17881 ggtgttgttt attacctttc ttgtaataag cttgttacct gataagattt ttggaaaaaa
    17941 taaaaaaatt tggaaaatag tttttgcaat attgacggca gtggcagcat tgtcatttat
    18001 gtactaagtt attttaagaa tgtagggaaa taaaccctac attcttttta gttttttctg
    18061 ttttctaaat tctatttatc caagcgcttc aacatttctt gcttcttcgc ttcaagttct
    18121 gcacgctttt cttcgatttc ggcatgtttt ttctcgagtt cagaacaact tgcaccattg
    18181 ctaaattctt ttcgccatca ggagataggg tgagtcgaca tgtctattac tcacccaaag
    18241 cagtcctaca aagcaggaat tttctgttac ttttttggaa atagtaacgt ttatacagct
    18301 ttgacacttc gtatcaaagc gccaaacaca ctccgaggga tttacagaaa gcagaaaagg
    18361 aatgatctgg tataagatca ttccttttct ctctttttct ttaagtaatt atatacaatg
    18421 tacgacgaag tcgtcattgc aatgctgatc caccacctaa aggaaacttt aaacaacatt
    18481 gataagataa agaatataaa caacgaaaat acgttatacc caattaattt tattgtatat
    18541 ctcatgatta aaagttaatc cttccgttgt taggaatggc atcattttta tcccataatt
    18601 gtgctaaata agtccccggt gataataaat ttatagcaaa ttctaaagca acatcattta
    18661 caaaccaact acctagatat ctagaaattg ctgaacgaat agcacttttt gctgcatgtt
    18721 ttccttttac tttaattaga tttgcaaggc ctgcagtagt tcctcctaat gctaaagcta
    18781 ttgcagtatc taatagagca cccatttgat taactgtaat accttgccaa gctgctctaa
    18841 atggagagta tgtaggtggg attgtataat cgccttgtaa ttgtcggtta attacttctt
    18901 tgatccattg ttgtgagacg tctggatgaa aagattggat ttcgtttgca agtgtattga
    18961 tttgttcttc tgttagagaa gtgacaggtt gaagttccat atttgtttca atttgtgata
    19021 cttgttcaga agcgtataca gctgaaacac ttggaatcgc tgatacaatt aacacaattg
    19081 acgtcaaaaa aaccgaaata aatttcatta atttgttcat gagcttttct cctttttatt
    19141 tgtatctgct tacattttat catatgctgt tattatagtc aaaaaaatat gctattatgt
    19201 taaaaaaata tttttcaaaa tataaatgga cggatttatt ttggatttta tttgttattt
    19261 tgacctgcct ctatattggt aaccatgatt tgtttactct caatcatcaa gaattctctt
    19321 ttcgtggtag cgtttggggt ctggtactgg ccttatatca cttactattc attgataagt
    19381 ttgttatatc gaatcgaaaa taaagattag agctatgctt gactgtgtac ttttaggatt
    19441 gattttggag gaagattttg tctctattat ttattatttt aaatttattt attttgtata
    19501 agatctattc tttgaggcgg gaaaaatcga aatacttgat ttatacggcc tatatcatat
    19561 ttggggtaaa tgtagtatat ggtattcaat ggttattaag agaactgatt tcaactattt
    19621 ccccttaatg tgtatggaaa ctataacaaa acgcataaga ttaaggtttg tgtacctgtt
    19681 cttatgcgtt tttataatat tgaagatttt cggtaagttt tatacctttg ggaagtctag
    19741 tttagaatgc tttcccaacc aaaatctctg cttcgatggt aatctctgtc agttggctcc
    19801 agtcaatctt gctctggtca acgtgaaaga ggagaggagt catactgagt agggcttgga
    19861 gttgttctgc tgtgatagtc ttagtcagag aggcagtttg actagatagg atggtaaagt
    19921 gttcctggaa atgctccttg atatcttggt tagaatactc cttgtttgtc agctggtcct
    19981 gtactctttg acggatttct ttgaggtgat tttcagttgg gataaccttt atcaagatac
    20041 cgtctttgga taaaacgcga cgaaattctc catagttggc aggtgagaag atatcaagca
    20101 gaatatccat gttagcgtct tttataggaa gtcgtgccaa gtcgccaacg aaccaattga
    20161 ctgcccagtt gggttcactt ttagcagcga tttggactga atctttggag atgtcaaagg
    20221 catagaaagt tttttcagag tgactttctt gtagtttgcg agaatagaat ccttcaccac
    20281 aaccgatatc caaaattgtt gtggtagttt ttgagcttgc aagcaagtca gatacagcat
    20341 ctaagatagc ttggtaaaag ccggcttcta ggatttgttg acggttttga aaattttcct
    20401 tgtcatagtt agcagattgc ttgatttgag gtgctagatt gacatagcca aatttcgcca
    20461 agtcaaaaga atgacggttg cagcacttga aattagtctc taacagagtc agattttctt
    20521 gacagatagg acaggcaaag gcagtcgcag aagcaaaacg ctgaagtttg ggcttgagat
    20581 ttgtattcat agtttaagtg tatcaaaaga ggcaaatgaa agcaacttta ggaataagta
    20641 gattcagtag aaataaaact aattctccaa tttatagaat gaaattgctt ttatatctaa
    20701 attgctatat aataatgata aggaggaaat aagtatgtta aaagaagtat taaccgttgc
    20761 aaaagttgcg aaaaaatctt cattattttt gggtggtgtc gcatttggta cccttggttt
    20821 gaaaatctta gcaagtaagg aagctaaaaa aggttattct aaagctttgg ctaaggctta
    20881 caagttgaaa gacgagctag atgcatctgt ttctgttgtg aagcaacatg gagacgatgt
    20941 cttgcaagat gccaaatatt tgtacgagca agagaaaaaa gaagagcaat tagatagcct
    21001 tataggtgaa taatatgtct tttaaagtgc tacatagagg ataccaacat atccgactat
    21061 catcttcttt ttcacttacc ttggatattc aagactatct tcgttccttg gcgagagatg
    21121 aaaaggggat tgagtctatc cagttttaca tggatcaaca gcactttact ctacgcataa
    21181 aagaaggctt ttctgtatta gataatgcag aagccttttt aaaaagaatt gataaaggga
    21241 aagtttctga gttgatgact cttcccattc gtagagaaga gagtgcttat tctattgttt
    21301 caggtgcagc ggttaagcgt gtactttttc gtagttttgt gccgtatcct attcgctata
    21361 tatggacttg ttatcaggct ttgggttata ttagagaagc ctatcaaaca ctagcgcgta
    21421 aggaactaac gatggaagtc ttggactgtt cggctatttt attgtccttg tttatgaacc
    21481 aatccaagac agctagcaat atcatgttta tgcttgattt ggggaatcat ttagatcagt
    21541 ggtccttgaa aaaaactgca acagatttag aacagagtct tcttgcaaaa gagagcgatg
    21601 tattcctagt acagggcgat acggttgtta gtatcaagag ttccgatgtt caaataggag
    21661 atgtcttgat cttatctcaa ggaaatgaaa ttctgtttga tggacaagta gtttcaggtt
    21721 taggtatggt caacgaaagt tccttgacag gagagagttt tccagttgaa aaaagagagt
    21781 ctgatttggt ttgtgcaaat acagtattag aaactggaga gttacgcatt cgtgtaacag
    21841 ataatcagat gaacagccgt attttacagc tgattgagtt gatgaagaaa tctgaagaaa
    21901 acaagaaaac gaaacaacgc tatttcatca agatggcgga taaagtcgtc aaatataatt
    21961 tcttgggggc tgggctgact tacctattga caggttcttt ttctaaggct atttctttcc
    22021 tattggtcga tttctcctgc gctttgaaaa tctctactcc tgtagcttat ttgacagtta
    22081 tcaaggaagg gttgaaccgt gaaatggtga ttaaggatgg agatgttctg gagaaatatc
    22141 tggaagttga tactttcttg tttgataaga caggaacaat cacaactagt tatcctatag
    22201 ttgaaaaggt gttacctttt ggagactata gtgaggaaga tattctcaga atcagtgcct
    22261 gtcttgagga acacatttat catcctattg ctaatgccat cgtcaagcaa gctgagatag
    22321 agggaattga acatgaggaa atgcatggga aactccaata tatcgcaagc aaggggatca
    22381 aatctcatat agatggccaa ccagttctta ttgggaatta tgtcttgatg caggatgagc
    22441 agattcatat cagttcagaa caaaatgctt taattgaaga gtacaagagt cactacaatc
    22501 tcttattctt ggcttatcaa aatgaattga ttggaatgtt ctgcattcat actcctttga
    22561 gaaaagaagc aaaaacagcc ttggataaac ttaaggcaca ggggaaaaaa ttgattctgg
    22621 caacaggaga caccttgatt aggacagagg aattagtcaa agatttgccc tttgatcagg
    22681 tctatacaga cttgaaacct gatgggaaat ttgagttagt agagaaactg cagaaagcag
    22741 gtcacactat tttgatggtt ggagatggat tgaatgactc agcggcttta actctatcag
    22801 atatcggtgt ggtgatgaat gagagtgcag atatttctaa gcagatgagt gatatcttat
    22861 tgttagataa tcgtttggat ttcttccaag agttggattc gttatcatca tctttgcaaa
    22921 cactcatcaa gaaaaatatt caggataccg ttgtcgtaaa tagtagtttg attggctttg
    22981 gcttatttaa ttggttcagt ccttcaaatc tctctatctt acataatcta acaaccttgc
    23041 gcattgtcct gcgtagcctg tctattaaaa atagatagat gagagttatt aacagcaaaa
    23101 aggagttacc tttctcgagg ttaactcctt tgtttataga taaatgttga atagtttagt
    23161 aagtcaatac aaagtatttt ttcttcccac gacggataac agtcagttca ttttctaact
    23221 tatcagcgtc actcaagaca tagtcaaggt cttggatgcg gtcgccgttt acgtagatgg
    23281 ctccgttttg gacgtcttca cgggcttggc gttttgagtt aactatacca gatgagacga
    23341 gcagttccac gatattgttg ttttcgtctg cctgtacttg gtagtttggc acaccacgaa
    23401 gtccttgttt gagctctttg acagaaaggt ttttgatgtt tcctgcaaag agttgctcag
    23461 tgatgttaag tgcttctttg taggcttctt ctccgtgaac aagtgtaaca acttcacgag
    23521 ccaagacttt ttgagccaag cgttcgtgtg gcgctgcttc aaattgttta cgaatatctt
    23581 caatctcatc aagtgacaag aaagtaaaga ttttcaagaa gcgaacagcg tcagcgtcca
    23641 tcacgttcat ccagaattgg tacatttcgt atggagaagt cttttcggga ttgagccaga
    23701 cggcatttcc ttctgattta ccaaattttt taccagttgc atctgtgatt agtggaacag
    23761 tgataacgtg accagtcttg tccgccttac gacgaagcaa ttcggtacca gctgtcatat
    23821 ttccccactg gtcagaacca ccgatttgaa gagtgacatt atggtcttgg ttaaggacga
    23881 agaagtcgta cccttgcatg atttggtaag cgaactcagt gtaagaaatt cctgtttcga
    23941 tccgtttttt aacagattcc ttactcatca tgtagttgac cgtgaagtac tttccaatgt
    24001 cacggaggaa gtcaatgaag ctgatgctgc caaaccagtc gtagttgttg accatgacag
    24061 ccttgttttc gccattttca aagtcaagaa aacgagaaag ttgtccttgg atagacttga
    24121 cccagccatc tactgtgtct tttgtttgga gactacgttc agcatctttg aaggacggat
    24181 ctccgatgag acctgtagca ccgccaacga gcgcataagg tttgtgacct gctagttgca
    24241 agcgacgact tgtcaagatt gcgacaaggt ggcctaggtg aaggctgtca gcagttggat
    24301 cgtagccagt ataataagaa acttgacctt cttctagggc tttacgcaaa gcttcttcat
    24361 cagtcgtttg aaatatcaaa ccacgctctt ttagctcatc aaaaatgtgc atgtgtcttt
    24421 tctccttttt aaaattattg tttctaccta ttgtatcaca aacttgggca atagcctagc
    24481 agaataggga agaaagtggc tattttattg aaaatttccc ttttgtggta taatagataa
    24541 agtgaggaaa tccatgcaaa atcaattaaa tgaattaaaa cgaaaaatgc tggaattttt
    24601 ccagcaaaaa caaaaaaata aaaaatcagc tagacctggc aagaaaggtt caagtaccaa
    24661 aaaatctaaa accttagata agtcagccat tttcccagct attttactga gtataaaagc
    24721 cttatttaac ttactctttg tactcggttt tctaggagga atgttgggag ttgggattgc
    24781 tttggggtac ggagtggcct tatttgacaa ggttcgggtg cctcagacag aagaattggt
    24841 gaatcaggtc aaggacatct cttctatttc agagattacc tattcggacg ggacggtgat
    24901 tgcttccata gagagtgatt tgttgcgcac ttctatctca tctgagcaaa tttcggaaaa
    24961 tctgaagaag gctatcattg cgacagaaga tgaacacttt aaagaacata agggtgtagt
    25021 acccaaggcg gtgattcgtg cgaccttggg gaaatttgta ggtttgggtt cctctagtgg
    25081 gggttcaacc ttgacccagc aactaattaa acagcaggtt gttggggatg cgccgacctt
    25141 ggctcgtaag gcggcagaga ttgtggatgc tcttgccttg gaacgcgcca tgaataaaga
    25201 tgagatttta acgacctatc tcaatgtggc tccctttggc cgaaataata agggacagaa
    25261 tattgcaggg gctcggcaag cagctgaggg aattttcggt gtagatgcca gtcagttgac
    25321 tgttcctcaa gcagcatttt tagcaggact tccacagagt cccattactt actctcctta
    25381 tgaaaatact ggggagttga agagtgatga agacctagaa attggcttaa gacgggctaa
    25441 ggcagttctt tacagtatgt atcgtacagg tgcattaagc aaagacgagt attctcagta
    25501 caaggattat gaccttaaac aggacttttt accatcgggc acggttacag gaatttcacg
    25561 agactattta tactttacaa ctttggcaga agctcaagaa cgtatgtatg actatctagc
    25621 tcagagagac aatgtctccg ctaaggagtt gaaaaatgag gcaactcaga agttttatcg
    25681 agatttggca gccaaggaaa ttgaaaatgg tggttataag attactacta ccatagatca
    25741 gaaaattcat tctgccatgc aaagtgcggt tgctgattat ggctatcttt tagacgatgg
    25801 aacaggtcgt gtagaagtag ggaatgtctt gatggataac caaacaggtg ctattctagg
    25861 ctttgtaggt ggtcgtaatt atcaagaaaa tcaaaataat catgcctttg atacaaaacg
    25921 ttcgccagct tctactacca agcccttgct ggcctacggt attgctattg accagggctt
    25981 gatgggaagt gaaacgattc tatctaacta tccaacaaac tttgctaatg gcaatccgat
    26041 tatgtatgct aatagcaagg gaacaggaat gatgaccttg ggagaagctc tgaactattc
    26101 atggaatatc cctgcttact ggacctatcg tatgctccgt gaaaagggtg ttgatgtcaa
    26161 gggttatatg gaaaagatgg gttacgagat tcctgagtac ggtattgaga gcttgccaat
    26221 gggtggtggt attgaagtca cagttgccca gcataccaat ggctatcaga ccttagctaa
    26281 taatggagtt tatcatcaga agcatgtgat ttcaaagatt gaagcagcag atggtagagt
    26341 ggtgtatgag tatcaggata aaccggttca agtctattca aaagctactg cgacgattat
    26401 gcagggattg ctacgagaag ttctatcctc tcgtgtgaca acaaccttca agtctaacct
    26461 gacttcttta aatcctactc tggctaatgc agattggatt gggaagactg gtacaaccaa
    26521 ccaagacgaa aatatgtggc tcatgctttc gacacctaga ttaaccctag gtggctggat
    26581 tgggcatgat gataatcatt cattgtcacg tagagcaggt tattctaata actctaatta
    26641 catggctcat ctggtaaatg cgattcagca agcttcccca agcatttggg ggaacgagcg
    26701 ctttgcttta gatcctagtg tagtgaaatc ggaagtcttg aaatcaacag gtcaaaaacc
    26761 agggaaggtt tctgttgaag gaaaagaggt agaggtcaca ggttcgactg ttaccagcta
    26821 ttgggctaat aagtcaggag cgccagcgac aagttatcgc tttgctattg gcggaagtga
    26881 tgcggattat cagaatgctt ggtctagtat tgtggggagt ctaccaactc catccagctc
    26941 cagcagttca agtagtagtt ctagcgatag cagtaactca agtactacac gaccttcttc
    27001 ttcaagggcg agacgataat tctctaaatg aagtggccaa tcaatggatt gccacttttt
    27061 tcctttcgtg ttacaataag ggtatgaatc agtatcagaa aaagattgtt aacggaaaaa
    27121 tttattcgct cctatccggc ttaatatggg gaatctgtgg aattttagga gagtacttct
    27181 ttactcatta tcaggtgtct tcgggctgga ttacctctat gcgtttgaca ctggcaggga
    27241 gtcttgtact catttggtct gcaatacaat taaaatcgca agtgctagat atttggcgag
    27301 acaagaaaaa ttacctgccc tttttagcct atgctatttt ggggattttt tcagttcagt
    27361 attttttcta tctctgttta gaatactcaa atgctacgac agcaactatt ttacagttta
    27421 ttagccctgt ctttatcctc ttttacaatc gcttggttta tcaaaaacga gcgtcaaaaa
    27481 gcgctgtttt ctatgttttg gttgccatgc tgggtgtttg cttgatggcg acaaagggag
    27541 atctctctca gttatccatg acgccgctag ctcttataac aggtttgctg agtgccatgg
    27601 gtgttatgtt taatgttatc ttgccccaac cttttgctaa gcgttatggt tttgttccta
    27661 cggttgggtg ggggatgatt ttggcaggtt tgtttagcaa tgtcctctcg ccggtttatc
    27721 agctttcctt tactcttgat atttggagta tcttgatttg cctcattatc gctttctttg
    27781 gaacggcttt tgcttttttc atttccatga aggctgtgtc cttggtttct cctttggtgg
    27841 tttccgttat cagtgccagt gaacctctct cttctgctct cttgagtgtt ttgttcttag
    27901 gattagtagt ggattggtcc ctccttctag ctatagcctt gattatttta cccatgatat
    27961 ttttgtctat agaagaagcg aaagaaagta gataaaaagt cttttcttaa ttctaaaagt
    28021 gtgctatact agaatagtca ataaaacacg gggagatagt tgtgaagagt atttttaggt
    28081 tgtatcggta ggggcttgct tttaccgaca gcacgtttta tctcacatcc ctaaaaaatc
    28141 atacctaaaa acagacaaaa aggtttcaaa tttgaggcct tttttggtag aataggtatc
    28201 attataacga accaggaggc acctatgact gctacaaaaa tgaacgctca agaaattatc
    28261 caatttatcg ccaatgctga aaagaaaacc agtgtcaaag taacctttga ggggcaactc
    28321 gcaactgctg tgcctagctc tgttgtcaaa ctaggaaatg tcctattcgg agactggaag
    28381 gacgtggctc cgcttcttga aggtttggta gaaaatcaag attatgttgt cgagcaagat
    28441 gctcgtaatt ctgcagttcc tttgctagat aagcgtgcta tcaacgctcg tatcgagcca
    28501 ggtgctatta tccgtgacca ggtggaaatt ggtgacaatg ctgttatcat gatgggagct
    28561 gttatcaata tcggtgctga aatcggtgct ggaaccatga ttgacatggg tgccatcctt
    28621 ggtggccgtg ctatcgttgg aaaaaatagc cacgttggtg caggtgcagt tttggcaggt
    28681 gtgattgagc cagctagtgc tgaaccagtc tgtgtcggag acaatgttct tatcggggct
    28741 aatgcagtgg ttatcgaagg agtccaaatc ggtagtggtt cagttgtcgc tgcaggagct
    28801 atcgttaccc aagatgtccc agaaaacgtg gtagtagcag gtgttccagc tcgtattatc
    28861 aaagaaattg atgcccaaac tcaacaaaaa acagcgctag aggatgcgct tcgtaccttg
    28921 taattgtaaa agtaaaaaag aggcggaacc ctttttccag cctctttctg ctatatcgga
    28981 ggacagatag atgttagatt tgattcagac tagacgagct ttacaccaga ttccagagat
    29041 tggcttggag gagttcaaga ctcaggctta tttgctggat gtgattgaga aattgactac
    29101 gggcaaggat tttgttcaaa ttcgtacttg gcggacaggg attttggtct acctgcaggg
    29161 aagtcagccg gagcgaacca ttggttggcg gacagatatt gatggcctgc ctatcgtcga
    29221 acaaacaggt ctacctttta cttctcaaca ccaaggtcgc atgcatgcct gtggtcatga
    29281 ttttcatatg accattgcct taggctgtct tgagcgcgcc cttgaggagc aacccaagaa
    29341 taatctgctc tttctatttc agcctgctga agaaaatgaa gctggtggta tgctcatgta
    29401 tgaggacggt gcttttggag attggttgcc aaaccaattc tatggtctcc atgttcgtcc
    29461 agatttgaaa gtcggccaga ttgcgactaa tactcataca ctctttgcag gaacttgcga
    29521 ggtgaagatc cgtttcaaag gtaaaggtgg ccacgcagct tttcctcatg aagccaatga
    29581 cgccttggtg gcggctagtt actttgtgac ccaagtgcag tcagttgtta gccgcaatgt
    29641 caacccaatc gagggagcag tggtgacctt cggcgttttt caagctggaa ccaccaacaa
    29701 tgtcatcaca gacacagctt ttttacatgg aactattcgt gccttgacac aggacatgag
    29761 tctcttggtg caaaagaggg taaaaacagt tgcagaaggg gttgcagctg cctttgatat
    29821 ggaagtcgaa gtggaactca aacaaggtgg atacctacct gttgagaaca atccagcctt
    29881 ggcgcgtgaa ctgatggact tctttgacga gaaagacgga atcgagttga ttgatatcga
    29941 acctgctatg acaggcgagg actttggtta tctcctttca aaggttgatg gcgtgatgtt
    30001 ttggctaggt atcgatagtc cctacgctct tcatcaccct caaatgagtc ctaaggaaga
    30061 agtcttagct attggggtgg ctgcggtgtc tagtttcctg aaaaagaagg cagcagaata
    30121 gagggcttgt ctatgaaatc ggaattacgc aagcaagtct tgcatgaaat gaaggctata
    30181 tctcaagagc aaaaacaggc tatagaccaa gctttaaccg agcgaatttt acaacacccc
    30241 ttttatcaag aagccaaggt catcgcaacc tacctctctt tttctcatga gtttcaaacg
    30301 cgggaactga ttgagcaggc gctgaaggac ggcaagaagg ttttgacacc taagacctat
    30361 cccaaggggc gcatggattt tgtggtctat gatccgcaac agttggtaaa aacttccttt
    30421 gccttactgg agccacaggg agatttggaa gtagtggatg catctcagat tgatttgatt
    30481 catgttcctg gcctggcttt tacgacggat ggatatcgga ttggatatgg tggaggttat
    30541 tatgaccgct atctggaaca tttttctggt cgtgctttga gtacgatata tccttgtcaa
    30601 attcaggact ttatacctga aaaccatgat attcctgttc aggaggtatt aattgatgaa
    30661 ggaaatcttt gatagacgtt accctgtgac gagtttcttc ctcttagtga cggccttggt
    30721 atttttacta atgttggtca ctgcaggcgg aaactttgac agggcagata cattatttcg
    30781 atttggagcc atgtatgggc cagctattcg cctctttccc gagcaggttt ggcgtctctt
    30841 gtctgccatt tttgttcata ttgggtggga acatttcatt gttaatatgc tttcacttta
    30901 ttatcttgga aggcaggtag aggagatttt cggttctaag cagtttttct ttctctatct
    30961 tttatcagga atgatgggca atctctttgt ttttgtattt agtcctaaat ccttagcagc
    31021 aggcgcctct acctctcttt atgggctatt tgccgcgatt attgttcttc gctatgcaac
    31081 tcgcaatcct tatattcaac agctagggca atcctatctg acactttttg tagttaacat
    31141 tattggaagt gttctgattc caggaatcag cctagcaggc catatcggtg gtgcagttgg
    31201 tggcgcattt ctagcagtta tctttccagt tagaggagaa aaacggatgt ataataccag
    31261 ccagagatta ggagcggtag tcttgttcgt aggactcgcc attttgcttt tctacaaggg
    31321 aatgggaatg tgacgaagtt gaaagaaaat ttgtgtaatg aaaaaagata aggcattttt
    31381 tgaaccttat ctttttattt tattttattc cttctcagtc aattcttttc caagttggat
    31441 gaggtaattc ttcaaatcat ctttgacttg tgggtgtttg agggcgtagt cgatggatgt
    31501 tttcatgaag ccaaacttgt ctccgacatc gtaacgagcc ccattgaact cacgagcaaa
    31561 tacacgttgt gttttattga gggtgtcgat tgcatctgtc agctgaattt catttcctgc
    31621 acctggagct tggttttcga ggatttggaa aatttcaggc gtgaggaggt agcgtccgat
    31681 aatagcaagg tcgctaggag cgtcctctgg agctggtttt tcaacaaagg tttcaacact
    31741 gtaaagacca tcttttcctt cgccttgcgg agcaataacc ccgtaagcag atacttcgtc
    31801 atgagggact ggcatgacag cgatagtaga cgcgtgggta cgctcgtagt catccatgag
    31861 ttgtttggta agtggaacag ccttttcgtc tgtgatatcc atcaagtcat caccaagcat
    31921 aacgacaaaa ggttcatttc cgacgaaagc cttagcttgc aaaacagcat ctccgagacc
    31981 gcgtggatga gtttggcgga taaaatgcag acgcatgtca gttgttttat caactagctt
    32041 caaaagatct gttttccctt tttctttgag gttatattcc aattcgaagt ttgaatcaaa
    32101 gtggtcctca atagaacgtt ttgatttacc agtgacaact agaatatctt caatacctga
    32161 tttgagagcc tcttccacga taaactggat agttggtttg tctacgattg gcaacatttc
    32221 tttggcaagg gccttggttg ctggtaaaaa tcgagttcct agtccagcag cagggatgac
    32281 tgcctttcta acttttgatg tcataaaaat cctttctata gagggttaag accactcatt
    32341 ttctgcttta aattcattgt tcatgatgtc ataaatggca tctttgatat tggttccgtg
    32401 ataaataact tggtaaatag cctgtgtaat gggcatatag actccaagtt cttgggctag
    32461 ttcataggct gctcgagtcg ttgaaattcc ttcgattacc atgcccatat tagcttctat
    32521 atcagctagg gattctcctc gtccgagagc atctccagct ctccagttac gagagtggat
    32581 ggaagttccc gttacgatca aatctcccac accagataag ccgctatagg tcaatggact
    32641 ggccccgagt gctaccccta ggcgggtgat ttctgctaaa cctcgagcga tgatggctgc
    32701 cttagcatta tcaccaaatc caagaccatg taaagctcca gcaccgacag caataatatt
    32761 tttaagagca ccagcagttt caaccccgat aacatccgta ttggtataaa gtcggaagta
    32821 gtgattacta aatagctcct gaacgtattg agctgtttgt aaatctttag aagcagcagt
    32881 gattaaagtt aggtcacgca caatggtttc ttccgcatga ctaggccctg aaacaacgac
    32941 aatatcactg cggagctgtt caggaatttc ttcttcaagg atagttgata atcgtttatg
    33001 gctatcaggt tctaatccct ttgaagcgtg catgatgata gccttatggt ccaaggtttg
    33061 tgcaacttgt tgggcaacaa gtcgtgtcac ttttgttggg acaacaaaca aaatcgcatc
    33121 cacatctttc aatgtttctg ctaagtcggt gtaggcaatg atattttcat ctagaacgac
    33181 atctttaaag tagtgcttgt tagtatgata ggtattaatt tcattgattt gctcgggaag
    33241 atttccccaa atacgtacct cgtgtccatt gtcatttaag acttgtgaaa gggcagttcc
    33301 ccaagaacca ggccccaaga cggcgacggt ttgtttttcc atgatttcct ccttgataga
    33361 gttctttcca ttattctatc atattctaga ggattttgca cttgcattac tggggtatgg
    33421 tggaaaaata cacaaagacc gagatgaagg gataaactct tagtctttag ttaaagtgag
    33481 aagaaatctg atagatagtt tgattcagta tatgctataa atagaggtaa acaactcagg
    33541 aggttcttgt aggttgcgag agtttggcga aaaaattaaa agattacgtt tggctaaaaa
    33601 aatcagtcgt tcagaatttt gtggtgatga gtctgaatta agtatccgtc aattaattag
    33661 aattgaaaat ggagaatcca gaccaacact aacaaagtta aaatatatcg ctgaacgttt
    33721 ggggggggtg aagattacaa gttgatgcca agttatatag agttggataa ggaataccta
    33781 gaattgaagt atttcttgat gaggactcct acatacgaag atgaaactat cgcccaaaag
    33841 aaagagagtg tttttgctaa gatttttgaa gagtattatg ataggctacc tgaggaagaa
    33901 agatttatca tcccaaatta ttcatatcta gcactagcga actacacagt tcaaaaatta
    33961 ccagaaaagc tagttgaaat actgtccttc tggtgatttt gcttaatttc tgatgttcga
    34021 gacatgattg aggagatttg tcttgatttt ttcctaaaaa agggcagact cctcccttgg
    34081 tttgatgctc gatttttaaa ataaggtgac ttattctgtt aggcatgttt tcccctgccc
    34141 tctagctcta tatggaacag ggagtatcag atttatctgg cagattgtat caaataaggc
    34201 ttgaaactgt tttgaatagg cgtatagact tgagaatttg agaatatgtc gtctagcagt
    34261 agagacatat tttccggcaa tatgaaggaa gagacgtcga aaacgcttga tagtcaagga
    34321 ctttacttca tcaccagcta gctgctttaa aaagaggtag agattataag ccagacagcc
    34381 catcatcata cgtacttcat tcttaatcat ggtcgaacta tctgtcttat ccccaaagaa
    34441 tcctgctttc ctttctttga taaagttttc agcattccct cgttcacgat agaattgaaa
    34501 cagctcctca ctatctacac tgcttaaatt gttcaaatga acttttttac aaccataaaa
    34561 aagagcactt aatcgtactc ttctctttta aggattagtt gaattaattc aaatccacta
    34621 gttctcctgt ttctaggtag actaggcgtt cacaaatgtt agcaatgtaa tcagcgaagc
    34681 gttccagatg tcctatgata taaaggtatt gagttccatt gggaattgag gtttcttggt
    34741 ctttcataag tccaatgatt tcctttgata aggcataata atattggtca atctgttcat
    34801 ctttttgagc aatactaata gcttttgagg cttggtgcaa aggaaaggca accaataaat
    34861 cggctagcat gctgagggat aatttaccca tttggtgtaa ctgttcttcg tcaggggcta
    34921 gttgattttc ttttagttgc aaaacagctt tggcaatgcc tgccatatgg tctcccatac
    34981 gttcaaggtc tgaacaagaa gacatgatgc taatcacaaa tcgaaggtca gacacttgtg
    35041 gctgttgcaa ggccaacaaa cgggcacagg tcaattcgat agcgctttga ccttggttga
    35101 tagcatgatc cttattgata attagctctg ccatctcctt gtctttggag gctaaggcca
    35161 gtaaggcttt tgaagctgtt tcaaggacaa gttgccctag tcctaaaaag gattgttcta
    35221 attcatgcaa ttctaagtca aattgatttc tcataggttt ttccttcctt atccgaaccg
    35281 tcctgaaata tagtcttctg tgcgctgatc ttttggattg gtaaacacgt caacggtatc
    35341 tccaaattcg caaatttctc ctgttaagaa aaaagcagtt ttatctgaaa tacgtgaagc
    35401 ttgttgcatg ttatgggtaa caatgataat cgtataatcc ttttttagtt gctgaatgag
    35461 gtcttcaatt tttaaagtgg agatagggtc taaggctgaa gtcggctcat ccattaacag
    35521 aacatcaggt tctactgcta aagctcgcgc aatgcaaagg cgttgctgct gaccgccaga
    35581 taaggacatg gcactctttt taagatcatc tttgacttct tcccaaatgg ctgccccttt
    35641 taaagatttc tccactaagg catctaattg ttttttgtct cgaataccat gtgtccttgg
    35701 accataagcc acgttatcat agatagacat ggcaaaggga ttaggctgtt gaaaaaccat
    35761 ccctacacgc ttgcgtagct gattaaggtt gaatttgcta ctataaatat cttgctcatc
    35821 taagaggact tggccttcaa tatggcaaga aggaaccaaa tcgttcatcc ggttaagggt
    35881 ttttagaaaa gttgatttgc cacaaccaga tgggcctatc aaggcagtaa tctgtctttc
    35941 tggtaattga atcgaaatat tttttaaggc ttgaaaatcc ccgtaaaata agtctaggtg
    36001 tctgactgaa aatgttccca tactaggaag ctcctttcac aagttttcga gataataagc
    36061 ttgatagagt atttatcatt aaaacagtaa taatcaaaat cacaccggta gcataggctt
    36121 cattgacatg tagcccctca cttgacagca tatacatatg cagggctaga gaacgacctg
    36181 aagacatgag actacttggc gtattggtag aggtacctaa tgtatacatg agggcagctg
    36241 tctcaccaac gatacggcca atagctagta tcactccagc taaaatacct ggcatggcaa
    36301 ctggtagaac aattctaaaa acagtccgta acttacctgc cccaagtcca taacttgctt
    36361 gacgcatgct atcactaaca gataaaaggg cttcttctgt tgagcgaata atgactggca
    36421 acaccatgat gactgaggtt aagattcctg ataacagaga gtattgaaaa cctaagaaga
    36481 ctacaaagaa gagcatgcca aacagaccaa aaacaatgga aggaatccca gacaaggtat
    36541 ctgaggccaa tcgcatgatt ttaacacaaa gggaatcttt ttttgtatat tccacaagat
    36601 aaaaaccagc aaaaatccct atgggcaagg ctaaaagaag agcaccaaag accagaataa
    36661 cggtggaaat aatcgctggc ataagggaaa tgttctcaga agtataagtc caagaaaaga
    36721 gggatagact tagatgaggt aagcctttga tgaggataaa accaatgatt aaaaagagag
    36781 agccaaaggt taaagctgaa aaacaataaa cgagaagttt tagcaggtat ttactcataa
    36841 gatgattttc ctttcaagta ggcaaagtag gcattaatca agagaataag gaaaaagaga
    36901 actgctgagg ttgcaataag ggcttcccta tgctgacctg atgcgtaagc catttccaga
    36961 acaatattgg ttgttaaggt tctggttcct gaaaagagtc cacttggaat aatcggctgg
    37021 ttgcctgcca ccaaaataac tgccatggtt tcacctactg cgcgaccgat tcctaaaata
    37081 actgctgata aaataccaga tctcgcagct ggcaagatga cactaaaaat actccgttca
    37141 tgactagctc ctagagccaa gctaccagaa taatacgttt tgggaactgt tcggatagca
    37201 gattctgaca aactgataat ggttggcaaa atcattattc ctaatagtaa cgaagcggtt
    37261 aggacactca tgccatttcc taaaaaggtt ctaatccaag gcaccaataa ttgtaggccg
    37321 aaaaaaccat aaacaataga tggaatggcc gccatcaagt tgatagctga ttttaagaag
    37381 ccatagacgg gctttggaca ataataaacc ataaacaccg atgtcaagat gcctgttggc
    37441 accccaatca caatcgctcc taaggtaatt aataaggaac caacgatcat tggtaaaata
    37501 ccatagcttg ccggaatgtt cgttggcgac caatcactgc ctaataaaaa acgggcaaag
    37561 ccgtagttag ccatgaaagg taagccatta ctaaaaataa agaaacagat tagcaaaata
    37621 gctacaacag ctactgttgc actcatgaaa aaaattgccc taaaaactgc ttctttgaag
    37681 gcttgttttg tcacatcttg tcctttctag tgaagaaagt aagggagata cgacacctcc
    37741 ctacttgcct tctttatctt attgtacgat gaaacgtctg catctcttta gagatttatg
    37801 gagcaaacat tttatttaat cttgtcccag gtggttaatt tgccactaaa aacgtctgca
    37861 agttcagcca tactgacttg gcttgcctta ttgtcattat tgaccacaac agcaataccg
    37921 tctaaagcaa tagcatcatg ggtgagactc ttaccttctt caggagttaa ttccctagaa
    37981 accataccaa tatcagcggt tttctcctta acagcggtaa tacctgctga agacccatta
    38041 gaggtaatat caatcgtaac ttctggattt tcttttttat aagcttctgc taatttttcc
    38101 attaaagaag atactgaagt ggaacctaca acagacaact tgcctgataa gtgttggctt
    38161 gtatattctg tggtttcggt tttagcttca ataaatttat tatctgtgac cacttgttga
    38221 ccttgtttgg agtggataaa gctgataaaa tcttgaccta gcttggaaag attagaagac
    38281 caaacaatgt tgaagggacg ttgaagaggg tattcaccat ctaaaactgt gtctcgacta
    38341 gccttgacac catcaatctc taaagccttg acagatttcg ttaaagatcc caaggagatg
    38401 tagccgatag cattagcatt cccttgaact gctgagagaa caccttctgt actattttga
    38461 atcacagctg ttttggcagt gttgtcaatt tttttatcac cgtctttttt gagaatccct
    38521 gtgatttctg tgaaggcacc ccgtgttcca gagccatttt ctcgtgaaat cacctcaatc
    38581 gttcctgaag ctgactgttt ggaagcagct gactgattgc cacaggcaac aagcccaaat
    38641 cctgataagc caatggctgc aagagtaagc atttttttga atttcataat aatcaccttt
    38701 atctctatgt atttttcttg tgtaggctta ctacatttat agtctaacaa gtctttgtaa
    38761 aggtttatcc ctgattcatg taaagattgt gtaaagaatc aaaaaaagcc acttttgaaa
    38821 aatggctgct cctaaaaata gctttaaaaa ttattagtcc tgtgcgaaag attggttagg
    38881 aagaaaaatc gtgaagcaac tgcctctgcc aagctgactc gtcaccgtga cttggccacc
    38941 taataattga ctgagttctt tgacaatggc aaggccaaga ccagtgccac cagtttgtct
    39001 gcttcgacct ttattaactc ggtaaaaacg ttcaaaaata cgatcctgct ctaattgact
    39061 aataccaatc cctgtatctg atacagaaat cttaatgcct tcgttcacct tttgggtctt
    39121 gacctcaatt tttccccctt gttcagtgta acggatggca ttggataaaa gattgagtaa
    39181 gatttgggaa agtaattgac tatctgatac gagggtgaca tcatctggca cctgcacctt
    39241 tagctgtaaa tccttcttct tgagctgagg ttgcaagctt tgagtcaaat cctgtacaaa
    39301 ttctgccaaa gaaagggtcg tccattgtat aggcatttgt tgagccttag ataaggtaag
    39361 aagatgctca acaatatgct caagacgcaa gctttctttg taaataatgt ctagaaagtc
    39421 atccttgagc gcttcttctt cagctgacat ccccttaatg gtttcagcaa agcccttaat
    39481 cgaagtaact ggtgtcctca attcatggga ggcatttgag acaaaggcta aatttaactt
    39541 ttcataagtt ctaatcgttg ttaaatcata tagcaagacg agcacagctt ccacagattg
    39601 ggtggggcta aaaacgggaa ctgctgtcac ttctaaaatc aagtcaccct catgaaaccc
    39661 acttacttct tgttttaacc ttgttttttg atcaaaggct tggtgaacta aatttcgaat
    39721 atccatccgt ttgaggtcat caagtgaact tatgtcgccg tccacatcgg gaaaataatg
    39781 aggcagagag cgactggata ataacatctg accttgagcg gaaactaaaa acgtccccat
    39841 ggttaggtgc gacagaagaa cctccattgt ttcggctagg tccttgtatt gctgatcctg
    39901 ttgggagact ttggttttta gggcagacac atactgagcc aaagacttta agtcttcttg
    39961 ccctttttct aaaaagtatt cactactggt caagagaggt tggtgcaagg tctcaaaagc
    40021 aacttcccat ttccaaaggc aaaagagcca gtagccacct tgtcccaaag aaagggctag
    40081 aagaaagaga ccgatgcctt tactgatcca agttaatgcc atccctgcaa tcagaatgag
    40141 gctaacactt agattgacta gccaaaattg aaggtagcgt ttcatctata actccttgaa
    40201 cttataacca taaccccgaa tggttcgaat aaattgaggg gctttaggat tgtcttcaat
    40261 tttttccctc aacttaccaa tatgaacgtc caccaaacgt gtttcctgcc caaagtcata
    40321 cccccagata cgttccaaaa gacgctctct agtcagtgtc atgttgggat gtttcataag
    40381 atagagcaag agttcaaatt cttttggggt caaactcagt aacttattcg ccttgtagac
    40441 ttcatgacgc tcagggtata ctttcaaggt cccaaatagc caagaatcgt cagcgatatt
    40501 atctgaatca tctccttctt gttctccttt agttcgcctg aggacagcct tgacacgcgc
    40561 cagcaattct ctagggctaa aaggcttggt caggtagtca tcagccccta attccaaggc
    40621 caaaacctta tcaaattcat cacttttcgc agaaaccatc ataattggag ttttgacgcc
    40681 tttggctctc agccgcttac aaacttccat gccatctaat tgtggtaaca tgatatcaag
    40741 caagataaaa tcaaagggtt ctgtttctgc caaagctaag gccttccgtc catttgttac
    40801 caattgagta gaaaagcctt ccttacttaa atggtagtca agcaatttca gaatgtgttc
    40861 ttcatcatcc actaataaga cttgttttgt catctattat ctcctattgg taacattata
    40921 acacaattat cagaaatcct aacattgcta aatcagatta aatttgctta tcaagactag
    40981 tatctggtca aacgctcaat catctccttg tgctctggat aggtcgccag tagatctacc
    41041 ctttcaaata attcaaaatc ctcaaattca aaaccaggag caacaagaca agaaaccaga
    41101 gcataatcct tatcaactgt tgatccccaa atagtgccct taggaacaca gtagtgaagt
    41161 tgttgccctt tggatatgtc caggcctaaa gtgactgctt cgtagtgacc atctgctgta
    41221 atcatgtgaa cagtaagtgg ggatcctgca tgaaaatacc agatttcatc tgctgtcaat
    41281 cggtgaaaat gtgaaggatt cgtttcttct aataagaaat aaatactggt ataaagcgcc
    41341 cttcccttac cagcaaggtt tatagtgtct gaagcttttt ttgtttgtct aaaatagcca
    41401 ccttcaacat ggggagctaa ctctagagtt cttatcaagt cttctttatc cgtcggagcc
    41461 aatgggttga agtaactctt gttcaaaggt ggtgttacga tttcaagaac tcctctcagc
    41521 tctgaggaca cgataatgat tgatgcgacg gaagtacaaa tcaatcgccc taaaaaaaga
    41581 attagcgaat tattctgg
//
LOCUS       DAVAZT010000013        40582 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVAZT010000013 DAVAZT010000000
VERSION     DAVAZT010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40582)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40582)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40582
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.013"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..139
                     /locus_tag="VQT45_000629"
     CDS             <1..139
                     /locus_tag="VQT45_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2358988.1"
                     /translation="RSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIINHELG
                     F"
     gene            342..572
                     /gene="blpU"
                     /locus_tag="VQT45_000630"
     CDS             342..572
                     /gene="blpU"
                     /locus_tag="VQT45_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HET2358989.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            1287..3440
                     /locus_tag="VQT45_000631"
     CDS             1287..3440
                     /locus_tag="VQT45_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HET2358990.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            3453..4802
                     /locus_tag="VQT45_000632"
     CDS             3453..4802
                     /locus_tag="VQT45_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HET2358991.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            4973..5680
                     /locus_tag="VQT45_000633"
     CDS             4973..5680
                     /locus_tag="VQT45_000633"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HET2358992.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            5882..9607
                     /locus_tag="VQT45_000634"
     CDS             5882..9607
                     /locus_tag="VQT45_000634"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HET2358993.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVTKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            9700..11142
                     /locus_tag="VQT45_000635"
     CDS             9700..11142
                     /locus_tag="VQT45_000635"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HET2358994.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            11179..12201
                     /locus_tag="VQT45_000636"
     CDS             11179..12201
                     /locus_tag="VQT45_000636"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HET2358995.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            12198..12743
                     /gene="purN"
                     /locus_tag="VQT45_000637"
     CDS             12198..12743
                     /gene="purN"
                     /locus_tag="VQT45_000637"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HET2358996.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIALVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            12827..13336
                     /locus_tag="VQT45_000638"
     CDS             12827..13336
                     /locus_tag="VQT45_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET2358997.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLIFFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            13361..14908
                     /gene="purH"
                     /locus_tag="VQT45_000639"
     CDS             13361..14908
                     /gene="purH"
                     /locus_tag="VQT45_000639"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HET2358998.1"
                     /translation="MTKRVLISVSDKADIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDGVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYDDAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGENKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            15030..16292
                     /gene="purD"
                     /locus_tag="VQT45_000640"
     CDS             15030..16292
                     /gene="purD"
                     /locus_tag="VQT45_000640"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HET2358999.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVSETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFFEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNITWTDKGVTLGVVVA
                     SKGYPLNYSKGVELPVKTDGDIITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            16695..17183
                     /gene="purE"
                     /locus_tag="VQT45_000641"
     CDS             16695..17183
                     /gene="purE"
                     /locus_tag="VQT45_000641"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HET2359000.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            17170..18261
                     /gene="purK"
                     /locus_tag="VQT45_000642"
     CDS             17170..18261
                     /gene="purK"
                     /locus_tag="VQT45_000642"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HET2359001.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            18271..18498
                     /locus_tag="VQT45_000643"
     CDS             18271..18498
                     /locus_tag="VQT45_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HET2359002.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            18561..19859
                     /gene="purB"
                     /locus_tag="VQT45_000644"
     CDS             18561..19859
                     /gene="purB"
                     /locus_tag="VQT45_000644"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HET2359003.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(19914..23852)
                     /gene="strH"
                     /locus_tag="VQT45_000645"
     CDS             complement(19914..23852)
                     /gene="strH"
                     /locus_tag="VQT45_000645"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET2359004.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEDDKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKESARTVNLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGSMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQTLNEVPKDLNRY
                     TAESVAAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVIEKKLPETGTHDSAGLVVAGLMATLAAYGLTKRKED"
     gene            complement(24167..24883)
                     /locus_tag="VQT45_000646"
     CDS             complement(24167..24883)
                     /locus_tag="VQT45_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2359005.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            25231..27018
                     /locus_tag="VQT45_000647"
     CDS             25231..27018
                     /locus_tag="VQT45_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HET2359006.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPVYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            27015..27491
                     /locus_tag="VQT45_000648"
     CDS             27015..27491
                     /locus_tag="VQT45_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET2359007.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            27519..28424
                     /locus_tag="VQT45_000649"
     CDS             27519..28424
                     /locus_tag="VQT45_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET2359008.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            28411..29226
                     /locus_tag="VQT45_000650"
     CDS             28411..29226
                     /locus_tag="VQT45_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2359009.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            29233..29637
                     /locus_tag="VQT45_000651"
     CDS             29233..29637
                     /locus_tag="VQT45_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2359010.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            29936..31102
                     /locus_tag="VQT45_000652"
     CDS             29936..31102
                     /locus_tag="VQT45_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HET2359011.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVAKPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTTLLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVVLGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            31218..32255
                     /locus_tag="VQT45_000653"
     CDS             31218..32255
                     /locus_tag="VQT45_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HET2359012.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGALLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            32463..33317
                     /locus_tag="VQT45_000654"
     CDS             32463..33317
                     /locus_tag="VQT45_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2359013.1"
                     /translation="MTYEYKSHIYLAETALNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREYYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            33467..33724
                     /locus_tag="VQT45_000655"
     CDS             33467..33724
                     /locus_tag="VQT45_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HET2359014.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(34100..34192)
                     /locus_tag="VQT45_000656"
                     /pseudo
     CDS             complement(34100..34192)
                     /locus_tag="VQT45_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(34228..34524)
                     /locus_tag="VQT45_000657"
     CDS             complement(34228..34524)
                     /locus_tag="VQT45_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2359015.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLISQGLTVTNVEGGMNAWPGQVE"
     gene            complement(34514..34675)
                     /locus_tag="VQT45_000658"
     CDS             complement(34514..34675)
                     /locus_tag="VQT45_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HET2359016.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTAQNLDGAYSLYKMV
                     NPEGVEYGN"
     gene            34745..35509
                     /locus_tag="VQT45_000659"
     CDS             34745..35509
                     /locus_tag="VQT45_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HET2359017.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLDEEI
                     DRYAREVGADCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            36122..37501
                     /locus_tag="VQT45_000660"
     CDS             36122..37501
                     /locus_tag="VQT45_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET2359018.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            37515..38180
                     /locus_tag="VQT45_000661"
     CDS             37515..38180
                     /locus_tag="VQT45_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HET2359019.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            38294..38389
                     /locus_tag="VQT45_000662"
                     /pseudo
     CDS             38294..38389
                     /locus_tag="VQT45_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            38535..38984
                     /locus_tag="VQT45_000663"
     CDS             38535..38984
                     /locus_tag="VQT45_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2359020.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDAFVTNFVYEKEGQSRKKSMSYESVLPVRQIFD"
     gene            39141..39551
                     /locus_tag="VQT45_000664"
     CDS             39141..39551
                     /locus_tag="VQT45_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HET2359021.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKRIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSETAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            39667..>40582
                     /gene="pavB"
                     /locus_tag="VQT45_000665"
     CDS             39667..>40582
                     /gene="pavB"
                     /locus_tag="VQT45_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HET2359022.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAV"
BASE COUNT        11240 a         7839 c         9487 g        12016 t
ORIGIN      
        1 gagaagcaag gttgagaata tctttgccaa agtaaaaacg tttaaaatgt tttcaacaac
       61 ctatcgaaat catcgtaaac gcttcggatt acgaatgaat ttgattgctg gtattatcaa
      121 tcatgaacta ggattctagt tttgcaggaa gtctaatagt aaaaaagtga ttagaaaaca
      181 tcttttttaa aaatagagat gattttgaaa caaaaaagct aattcaagac gtttcgatgc
      241 caattcaaga tttggatgaa aaaaattaat agatactgtt atactaaact tgtcaagttt
      301 gtaacaagac aaatattaaa aataaaaaag aggtattcgt tatgaataca aaaaagatgt
      361 cacaatttga aattatggat actgagatgc ttgcttgcgt tgaaggtggc ggatgcaatt
      421 ggggagattt tgccaaagca ggtgttggag gaggagcagt acgaggtctt cagctaggaa
      481 ttaaaacaag aacatggcaa ggtgcagcaa ctggtgctgc gggaggagct atacttggag
      541 gtgtggccta tgcagcgaca tgttggtggt aattatggat tttaaaagtt ttattattgg
      601 tttagtagtt ggtatatttg gtccttatat ggatgattta attagaaaaa aatttttaaa
      661 gtcttcggag aagaaaacag aaaaatctgt taaaaaataa tcaaaactat aaatgatgaa
      721 tctgaatcaa aattattttg cgcatgtaaa gaggagtctt atagtaacga gtcaaaaaag
      781 gagtaactat gaatcgtaat ttagaacggt gttatctatt ctgactagga atagatcata
      841 ccagaggtag cttagaaata gcagggacat tagaaattga agtaataaat aggatgtcgt
      901 aagtgttact atcaatgatt tatttgtttc aagcttgcct agggtgacag taaaaaatca
      961 atttcctttc aatagcatat ttttagtggg caggactctt gttctgccta tttttttatc
     1021 caaaaagtgc agttgggagg gagataggct catttgggaa ggaagtccag tttttgttta
     1081 gtgattgggg taagatagtt gttatcagat gagtttatac tcttcgaaaa tcaaattcaa
     1141 accacgtcaa cgtcgccttg ccgtatatat gtgactgact tcgtcagtcc tatctacaac
     1201 ctcaaaacag tgttttgagc agcctgcggc tagtttccta gtttgctctt tgattttcat
     1261 tgagtattag ggaaaaggag atgaatatga aatttgggaa acgtcactat cgtccgcaag
     1321 tggatcagat ggactgcggt gtagcttcat tagccatggt ttttggctac tatggtagtt
     1381 attatttttt ggctcacttg cgagaattgg ctaagacgac catggatggg acgacggctt
     1441 tgggcttggt caaggtggca gaggagattg gttttgagac gcgagccatt aaggcggata
     1501 tgacgctttt tgacttgccg gatttgactt ttccttttgt tgcccatgtg cttaaggaag
     1561 ggaaattgct ccactactat gtggtgactg ggcaggataa ggatagcatt catattgccg
     1621 atccagatcc cggggtgaag ttgactaaac tgccacgtga gcgttttgag gaagaatgga
     1681 caggagtgac tctttttatg gcacctagtc cagactataa gccttataag gaacaaaaaa
     1741 atggtctgct ctcttttatc cctatattag tgaagcagcg tggcttgatt gccaatatcg
     1801 ttttggcaac actcttggta accgggatta acattgtggg ttcttattat ctgcagtcta
     1861 tcattgatac ctatgtgcca gatcagatgc gttcgacact agggattatt tctattgggc
     1921 tagtcatcgt ctacatcctc cagcaaatct tgtcttacgc tcaggagtat ctcttgcttg
     1981 ttttggggca acgcttgtcg attgacgtga ttttgtccta tatcaagcat gtttttcacc
     2041 tccctatgtc cttctttgcg acacgcagga caggggagat cgtgtctcgt tttacagatg
     2101 ctaacagtat catcgatgcg ctggcttcga ccatcctttc gattttccta gatgtgtcaa
     2161 cggttgtcat tatttccctt gttctatttt cacaaaatac caatctcttt ttcatgactt
     2221 tattggcgct tcctatctac acagtgatta tctttgcctt tatgaagccg tttgaaaaga
     2281 tgaatcggga taccatggaa gccaatgcgg ttctgtcttc ttctatcatt gaggacatca
     2341 acggtattga gactatcaag tccttgacca gtgaaagtca gcgttaccaa aaaattgaca
     2401 aggaatttgt ggattatctg aagaaatcct ttacctatag tcgagcagag agtcagcaaa
     2461 aggctctgaa aaaggttgcc catctcttgc ttaatgtcgg cattctctgg atgggggctg
     2521 ttctggtcat ggatggcaag atgagtttgg ggcagttgat tacctataat accttgctgg
     2581 tttactttac caatcctttg gaaaatatca tcaatctgca aaccaagctt cagacagcgc
     2641 aggttgccaa taaccgtcta aatgaagtgt atctagtagc ttctgagttt gaggagaaga
     2701 aaacagttga ggatttgagc ttgatgaagg gagatatgac cttcaagcag gttcattaca
     2761 agtatggcta tggtcgagac gtcttgtcgg atatcaattt aaccgttccc caagggtcta
     2821 aggtggcttt tgtggggatt tcagggtcag gtaagacgac tttggccaag atgatggtta
     2881 atttttacga cccaagtcaa ggggagatta gtctgggtgg tgtcaatctc aatcagattg
     2941 ataaaaaagc cctgcgccag tacatcaact atctgcctca acagccctat gtctttaacg
     3001 gaacgatttt ggagaatctt cttttgggag ccaaggaggg gacgacacag gaagatatct
     3061 tacgggcggt cgaattggca gagattcgag aggatatcga gcgcatgcca ctgaattatc
     3121 agacagaatt gacttcggat ggggcaggga tttcaggtgg tcaacgtcag agaatcgctt
     3181 tggcgcgtgc tctcttgaca gatgcgccgg tcttgatttt ggatgaggcg actagcagtt
     3241 tggatatttt gacagagaag cggattgtcg ataatctcat ggctttggac aagaccttga
     3301 ttttcattgc tcaccgcttg actattgctg agcggacaga gaaggtggtt gtcttggatc
     3361 agggcaagat tgtcgaagaa ggaaagcatg ctgatttgct tgcacaggga ggcttttacg
     3421 cccatttggt caatagctag aaagaggaga ggatgaaacc agaattttta gaaagtgcgg
     3481 agttttataa tcgtcgttac cataattttt ccagtagtgt gattgtaccc atggcccttc
     3541 tgctcgtgtt tttacttggc tttgcaactg ttgcagagaa ggagatgagt ttgtccacta
     3601 gagctactgt cgaacccagt cgtatccttg caaatatcca gtcaactagc aacaatcgta
     3661 ttcttgtcaa tcatttggaa gaaaataagc tggttaagaa gggggatctc ttggttcaat
     3721 accaagaagg ggcagagggt gtccaagcgg agtcctatgc cagtcagttg gacatgctaa
     3781 aggatcaaaa aaagcaattg gagtatctgc aaaagagcct gcaagaaggg gagaaccact
     3841 ttccagagga ggataagttt ggctaccaag ccacctttcg cgactacatc agtcaagcag
     3901 gcagtcttag ggctagtaca tcgcaacaaa atgagaccat cgcgtcccag aatgcagcag
     3961 ctagccaaac ccaagccgaa atcggcaacc tcatcagtca aacagaggct aaaattcgcg
     4021 attaccagac agctaagtca gctatggaaa caggtgcttc cttggccagt cagaatctag
     4081 cctactctct ttaccagtcc tacaagtctc agggcgagga aaatccccaa actaaggttc
     4141 aggcagttgc acaggttgaa gcacagattt ctcagttaga atctagtctt gctacttacc
     4201 gtgtccagta tgcaggttca ggtacccagc aagcctatgc gtcagggtta agcagtcaat
     4261 tggaatccct taaatcccaa catttggcaa aggttggtca ggaattgacc cttctagccc
     4321 agaaaatctt ggaggcagag tcaggtaaga aggtacaggg aaatctttta gacaagggga
     4381 aaattacggc gagtgaggat ggggtgcttc atcttaatcc tgagaccagt gattctagca
     4441 tggttgcaga aggtgcccta ctagcccaac tttatccatc tttggaaaga gaagggaaag
     4501 ccaaactcac agcctatcta agttcaaaag atgtagcaag aatcaaggtc ggtgattctg
     4561 ttcgctatac tacgactcat gatgccggga atcaactttt cctagattct actattacaa
     4621 gtattgatgc gacagctact aagactgaga aagggaattt ctttaaaatc gaggcggaga
     4681 ctaatctaac ttcggagcag gctgaaaaac ttaggtacgg ggtggaaggc cgcttgcaga
     4741 tgattacggg caagaaaagt tatctacgtt attatttgga tcaatttttg aacaaagagt
     4801 aatgttcgtg tttttagagt taaataattt ttaaactgtg agaaagattc ttcttgcagt
     4861 tttttcttta caatttttaa aaaaacatct gctatttatt cggttaaatt cttgtgtttt
     4921 ttggtttttt gtggtaaaat gtgctcaagt aatacgaaag gcgaacttta aaatgtcaaa
     4981 acaattgatc tattcgggaa aagctaaaga tatctataca actgaggatg aaaatcttat
     5041 tatttcaact tacaaggacc aggcgactgc tttcaacggt gtcaagaagg agcagattgc
     5101 aggtaaggga gtcttgaata atcagatctc atcttttatt tttgagaaat taaatgcggc
     5161 tggtgtggcg actcactttg tggagaaact ttcagacacg gaacaactca ataaaaaggt
     5221 taagattatt cctttggaag tcgtgctccg caactatact gctggttcct tttcaaaacg
     5281 ttttggtgtg gatgagggaa tcgccttgga gactccgatt gtcgaatttt actacaaaaa
     5341 tgatgatttg gatgatccat ttatcaatga tgagcatgtg aaattcctac agattgcggg
     5401 tgaccagcag attgcctact tgaaggaaga aacgcgtcgt atcaatgaac tattgaaagt
     5461 ctggtttgct gagattgggc ttaaattgat tgactttaag ctagagttcg gttttgacaa
     5521 ggatggcaag attatcttgg cagacgaatt ttcaccagat aactgccgct tgtgggacgc
     5581 tgatggcaac cacatggata aggatgtttt ccgtagagga ttgggagaac taaccgacgt
     5641 ttatgagatt gtttgggaaa agttgcagga attgaaataa tctgtttgca acggaaaacc
     5701 ttcgtctctc aactaaaagg actcaggctg aaaaggtccc ccagaccttt tcactctgta
     5761 gagaactagg tgaactaaca gatgtttacg aaattgtctg ggaaaagttg cagggtttaa
     5821 aataacaacc tcaaggctgt ttgggaatat tgcaagagct gaaataaagg aataagaatt
     5881 gatggataaa cgtatttttg ttgaaaaaaa ggctgatttt caggtcaagt cagagagttt
     5941 ggttagagag ctccagcaca acttgggact gtcaagcttg aaaagtattc gtattgtgca
     6001 agtatatgat gtatttgact tggctgagga cttgtttgca cctgcagaga agcacatttt
     6061 ctctgagcag ggaaccgacc atgttttaga tgaagtatct gtgcaggcgg atcttgctaa
     6121 ctatgctttc tttgccattg aaagtctgcc agggcagttt gaccagcgtg cagcttcgtc
     6181 acaggaagcc ttgcttttgt tgggaagttc gagtgacgtg acagtcaaca cagcccaact
     6241 ttacttggtg aataaagata ttgatgcgac tgagttggaa gctgtcaaaa actacctgct
     6301 caatccagtt gattctcgtt tcaaggatat cacgacaggg attgccaagc aggagttttc
     6361 agagtcagac aagaccattc caaaattgac tttctttgaa agctatacag cagaagactt
     6421 tgctcgctac aaggccgagc aagggatggc catggaagtg gatgatttgc tctttatcca
     6481 agactacttt aagtcaatcg ggcgcgtgcc aactgagact gaactcaagg ttttggacac
     6541 ttactggtct gaccactgcc gtcatacgac ttttgagaca gagttgaaac acatcgactt
     6601 ttcagcttct aaatttcaaa agcaattgca gtcaacctat gacaagtata ttgccatgcg
     6661 cgaggagtta ggtcggtctg aaaaaccaca aaccttgatg gatatggcga ctattttcgg
     6721 tcgttatgag cgtgctaacg gacgattgga tgatatggaa gtctctgacg aaatcaatgc
     6781 ctgctcagtt gaaattgaag tggatgttga tggtgtcaag gaaccttggc tcctcatgtt
     6841 taaaaatgaa acccacaacc atccaacaga aattgagcca tttggtggag cggctacctg
     6901 tatcggtgga gctattcgtg atccgttgtc aggccgttcc tatgtttacc aagccatgcg
     6961 tatttcaggt gctggtgata ttacagcacc gatttcggaa actcgtgctg ggaaattgcc
     7021 acaacaagtc atttctaaaa cagcagctca tggttattct tcatatggta accagattgg
     7081 gcttgccaca acctacgttc gtgaatactt ccacccaggc tttgtagcta aacgtatgga
     7141 acttggtgcc gttgttggtg cggctcccaa gggcaatgtt gtccgtgaaa aacctgaagc
     7201 aggtgatgtg atcatccttc tcggaggcaa aacaggtcgt gatggtgtcg gtggtgcgac
     7261 gggctcttct aaggttcaaa cagttgagtc tgtagagact gctggtgctg aggttcaaaa
     7321 aggaaatgcc atcgaagaac gcaagattca gcgcctcttc cgtaatggca atgtcactcg
     7381 tctgatcaag aagtccaatg actttggggc aggcggcgtc tgtgtggcta tcggtgaatt
     7441 ggcagacggt cttgaaatcg acctcaacaa ggtgcctctt aaataccagg gcttgaatgg
     7501 tacagaaatt gccatctctg aatcacaaga acggatggcg gtcgtggttc gtcctgaaga
     7561 tgtggatacc ttcgttgccg aatgtaacaa agaaaatatt gatgctgttg tggtggcgac
     7621 agtaactgaa aaaccaaatc ttgtcatgca ctggaatggt gagacaatcg ttgacttgga
     7681 gcgtcgtttc cttgacacca atggtgtgcg cgtggttgtc gatgccaaag ttgtggacaa
     7741 ggatgtcaaa ctcccagaag agcgtcaaac atctgctgaa acactggaat cagataccct
     7801 tacggttcta tctgacctca accatgcaag tcaaaaagga ttacagacta tctttgactg
     7861 ctctgttgga cgctcaacgg ttaatcaccc acttggtggt cgttaccaac tcacaccaac
     7921 tgaggcatct gtgcagaaat tgccagttca acacggtgtg actcatactg cgtcggtcat
     7981 tgctcaaggt ttcaacccat atgtagctga atggtctcca taccacggtg ctgcttatgc
     8041 ggttatcgaa gcaactgctc gtttggtggc tgctggtgcc aactggtcta aggctcgttt
     8101 ctcttaccaa gaatatttcg agcggatgga caagcaagca gagcgtttcg gtcagccagt
     8161 agctgctctt ctaggttcta ttgaagcaca aattcagctt ggcttgccat ctatcggtgg
     8221 taaggactcc atgtctggta cctttgaaga attgaccgtt ccgccaacct tggttgcctt
     8281 tggggtgacg acggcagata gccgtaaggt gctctctcca gaatttaaag ctgttgggga
     8341 aaatatctac tacatcccag gtcaagccct ctctgcagag attgattttg acttgattaa
     8401 gaaaaatttt gctcagtttg aagcaagcca agctgaccat aaagtgacgt ctgcatcagc
     8461 tgtcaaatac ggtggtgtag ttgaaagttt ggctcttgct acctttggaa actatattgg
     8521 tgcagaggtg accttgcctg aacttaaaac agctttgaca gctcaattag gcggctttgt
     8581 cttcacatct cctgaagaaa ttgctggagt agagaagatt ggacaaacga aagcagactt
     8641 tacactgact gtcaacggtg tgaagctaga tggacacaag cttgacagtg catttcaagg
     8701 gacattggaa gaagtttacc caacagaatt tacccaagcg aaagaactag aagaagtacc
     8761 agctgtggca tcagatgttg tgattaaagc caaagaaaag gttgaaaaac ctgtggttta
     8821 catcccagtc tttccaggaa ccaactcaga atatgattca gctaaggcct tcgaaaaaga
     8881 aggtgcagag gtcaatttgg tgccattcgt gaccttgaat gaagaagcta ttgtcaagtc
     8941 agttgaaact atggttgaca atatcgacaa gactaatatt ctcttctttg ccggtggatt
     9001 ctcggctgcg gatgaaccag atggttcagc taagtttatc gtcaatatcc tgcttaatga
     9061 aaaagtgcgt gtggctattg atagctttat cgcccgtggt ggcttgatta tcggtatttg
     9121 taatggattc caagccttag tcaaatcggg tctcctacca tacggaaact ttgaagatgc
     9181 taacagtact agtccaaccc tcttctacaa tgatgccaac caacacgtga ccaagatggt
     9241 ggaaactcgc attgccaata ccaactcacc atggttggct ggtgtgcaag tgggcgatat
     9301 ccacgctatt cctgtttcgc acggtgaagg gaagtttgtc gtgacggctg aggaatttgc
     9361 agagctccgt gacaatggac aaattttcag ccaatacgtt gactttaacg gtaaaccaag
     9421 tatggattct aagtacaatc cgaatggttc tgtccatgcc atcgaaggaa ttaccagcaa
     9481 gaatggtcaa atcatcggta agatgggcca ctcagaacgt tatgaggatg gtcttttcca
     9541 aaatatccca ggcaataaag accaacacct gttcgcatca gcggttaaac atttcactgg
     9601 aaaataagac ttacagattt tctaatagat agtatcagta atgtaaaagt catgtaaatc
     9661 tagctcttga tgattacaaa tgaaaattag gtataaaaaa tgacatacga agtaaaatct
     9721 cttaatgaag aatgtggtgt tttcggtatt tggggacatc cagatgctgc taagttgacc
     9781 tattttggac tccacagtct tcaacaccgt ggtcaggagg gggcaggaat cctctccaat
     9841 gatcaaggac aactgaagcg ccatcgtgac atggggcttt tatcagaagt tttcagaaat
     9901 ccagccaatt tggataaatt gacaggagct ggtgcgattg ggcatgtgcg ttatgcgact
     9961 gctggcgaag cttctgttga taacatccag cccttcctct tccgttttca cgatatgcag
    10021 tttggcttgg ctcataatgg aaatctgacc aatgcagcct ctctcaagaa agaactggaa
    10081 caaagaggag caattttcag cgcgacttcg gactctgaaa tcttggctca cctcattcgt
    10141 cgtagtcata atcctagcct gatgggcaaa atcaaggaag cgctcagcct tgtcaaaggt
    10201 ggttttgcct atatcttgct gtttgaggac aagttgattg cggctcttga ccctaatggc
    10261 tttcgtccgc tttctatcgg gaaaatggcc aacggagcgg tggttgtttc ctctgaaacc
    10321 tgtgcttttg aggtcattgg tgccgagtgg attcgtgatt tgaagccagg tgagattgtg
    10381 atcattgatg acgagggcat tcagtatgac agctatacag atgatactca gttggcgatt
    10441 tgttctatgg agtatatcta ctttgctcgc cctgattcta atatccacgg tgtcaatgtc
    10501 catacggcac gtaagagaat gggagcgcaa ttggcgcgag aatttaagca tgaggcagat
    10561 attgtagttg gtgtgcccaa ttcttcccta agcgcggcta tgggatttgc ggaagaatca
    10621 ggcttaccaa atgaaatggg tctgatcaaa aaccaataca cccagcgaac ttttatccaa
    10681 ccgactcaag aattgcggga gcaaggagtg cggatgaaac tgtctgctgt ttcgggtgtt
    10741 gtcaaaggca aacgtgtggt catggtggat gattccattg tacgtggaac aacctctcgt
    10801 cgtatcgttc agctcttgaa agaagcgggt gcgactgagg ttcacgttgc cattggaagt
    10861 cctgcactag cgtatccatg tttctacggg attgatatcc agacccgtca ggagctgatt
    10921 gcagccaatc atacggtcga agaaactcgc caaatcattg gtgcggacag tctgacttat
    10981 ctttcaattg atggcttgat tgagtcgatt ggtatcgaaa cagatgcgcc gaacggtggt
    11041 ctctgtgtcg cttactttga cggtgactac ccaacgcctc tctatgacta cgaagaagac
    11101 tatcgtagaa gtttggaaga aaagaccagt ttttacaagt aggcgacaga ttctccatta
    11161 aagaaaagga aaaaacaaat gacaaataaa aatgcatatg cccagtcggg tgtggatgtt
    11221 gaagcgggtt atgaagttgt tgaacggatt aaaaagcacg tggcccgtac ggagcgtgca
    11281 ggtgtcatgg gagctcttgg tggctttggt ggtatgtttg acctttccaa gactggggtt
    11341 aaagaacccg tcttgatttc agggactgac ggtgtcggaa ccaagctcat gttggctatc
    11401 aagtacgaca agcacgatac catcgggcag gactgtgtgg ccatgtgtgt caacgacatc
    11461 attgctgcag gtgcggaacc cctctatttt ctcgactacg tagcgacagg gaagaatgaa
    11521 ccagctaagc tagaacaagt ggttgctggt gtggcagaag gttgtgtgca ggctggtgct
    11581 gccctcatcg gtggggaaac ggctgaaatg ccgggcatgt acggcgaaga cgactatgac
    11641 ttggctggtt ttgcggtcgg tgtggctgaa aaatctcaaa tcattgacgg ttcaaaggtg
    11701 gtagagggag atgttcttct cggacttgct tcaagtggga ttcactcaaa tggttactct
    11761 ttggttcgtc gtgtctttgc ggattacaca ggtgaggaag tcctaccaga attggaaggc
    11821 aagaaactta aggaagttct acttgagccg actcgtatct atgtcaaggc tgtcttgccg
    11881 ctcatcaaag aagagttggt caacggcatt gcccacatca caggtggtgg ctttatcgaa
    11941 aatgtccctc gtatgtttgc agatgaccta gctgctgaaa ttgatgaaag caaagttcca
    12001 gtgcttccaa ttttcaaagc ccttgaaaaa tatggtcaga ttaaacacga agaaatgttt
    12061 gaaatcttca atatgggtgt gggacttatg ttggcggtca gccctgaaaa tgtagagcgt
    12121 gtaaaagaat tgttggatga agcagtctat gaaattggtc gcatcgtcaa gaaagaaaac
    12181 gaaagtgtca ttatcaaatg aaaaaaatag cggtttttgc ctctggtaat ggctcaaatt
    12241 ttcaggtgat tgccgaagaa tttccagtgg agtttgtctt ttcagaccat cgtgatgcct
    12301 atgtgcttga gcgtgcaaag cagctcggcg ttctgtccta tgcttttgaa ctcaaggagt
    12361 ttgagagcaa ggcagactac gaagcagccc ttgtcgaact cttggaagaa caccagattg
    12421 ccttggtttg cctagcaggc tacatgaaaa tcgttggacc aaccttattg tcggcttatg
    12481 aaggtcggat tgtcaacatt catccagcct acttgccaga atttccagga gctcatggga
    12541 ttgaggatgc ttggaatgct ggcgtgggtc agtctggtgt gaccattcac tgggtggatt
    12601 cgggtgtgga tacaggccag gtcatcaaac aggttcgtgt gccacgacta gctgatgata
    12661 ccattgacag atttgaagct cgcatccatg aagcagagta caggttgtat ccggaagtag
    12721 tgaaggctct atttacagat tgactttttg atgattcata tgatatcttt gattttaaat
    12781 tggagtcagt gtttgttgaa gacggcttca aacggaggta tttgtaatgt tagaatctaa
    12841 aaaaacaact cgatatgtat tttatgtcta tctgatgtta ttaacttggg gaatcttatt
    12901 taagtttgaa acaaatcctg aatttatagc atttttctta gctccaaggt atatcaattg
    12961 gattccattt tcagaaccac taatagtcga tggaaaaatt gtttttgctg aaatgttatt
    13021 taatctgatt ttctttattc cattaggtgt ttgtttccct ttgataaaaa ctaatttatc
    13081 tagtttaaga atagtcggga caggtttctt gattagttta ttgtttgagt gcttacagta
    13141 tattttagca ataggtataa cagatataac ggatttgact ttaaatacgc taggtgtctg
    13201 tgtaggctta ctgatttatc aaatttttat aagagtgttc aaatcacaga ctagaaaatg
    13261 gatcaatatc ttaggtatgc ttagccttgg ttttgcttat cttgttttac tgttactgca
    13321 tttaattggt gtttaactaa tgattaaaaa ggagaatata atgactaaac gcgtcttaat
    13381 cagcgtctca gacaaagcgg acattgttga atttgcccaa gaactcaaaa aacttggttg
    13441 ggagattatc tcgacaggtg gaactaaggt tgcccttgat aatgctgggg tggataccat
    13501 tgctatcgat ggtgtgactg gtttcccaga aatgatggac ggtcgtgtga agaccctcca
    13561 cccaaatatc cacggagggc ttctcgctcg tcgtgacttg gatagccact tggaagcggc
    13621 taaggacaac aagattgagc tcattgacct tgtggtggtc aacctttacc catttaagga
    13681 aactatcctt aaaccagatg tgacttatga tgatgcagtt gaaaatatcg atattggtgg
    13741 gccatctatg cttcgttcag cagcgaaaaa tcatgccagt gttacagttg tggtagatcc
    13801 tgctgactac gctgtggttt tggacgaatt ggcagcaaac ggcgaaacct cttatgaaac
    13861 tcgccaacgt ttagcagcca aagtatttcg tcacacagcg gcttatgacg ccttgattgc
    13921 agaatacttc acagctcaag tgggtgaaaa caagcctgaa aaactcactt tgacttatga
    13981 cctcaagcaa ccaatgcgtt acggtgagaa tcctcaacaa gacgcggact tttaccagaa
    14041 agctttgcct acagactact ccattgcttc agccaaacag ctcaacggga aagaattgtc
    14101 atttaataat atccgtgatg cagatgctgc tatccgtatc atccgtgact tcaaagatag
    14161 tccaaccgtt gtggctctca aacacatgaa tccatgtgga attggtcaag ctgatgacat
    14221 cgagactgct tgggactacg cttatgagtc tgacccagtg tctatctttg gtgggattgt
    14281 cgtcctcaac cgtgaggtgg atgctgcgac agctgagaag atgcacggcg ttttcctcga
    14341 aatcatcatt gcaccaagct atacggatga agcgctagcc attttgatca ataaaaagaa
    14401 aaacttgcgt atccttgcct tgccatttaa tgctcaagag gctagcgaag tggaagcaga
    14461 atacacaggt gtagtcggtg gacttctcgt gcaaaatcaa gacgtggtca aggaaagccc
    14521 agctgactgg caagtggtga ctaaacgtca gccaactgag acagaagcga ctgctcttga
    14581 gttcgcttgg aaggctatca agtacgtcaa atcaaatggt attatcgtga ccaacgacca
    14641 catgacactt ggtgttggtc caggtcaaac caaccgtgtg gcttctgttc gccttgccat
    14701 tgaccaagcc aaagatcgtc tggacggggc ggtccttgct tcagatgcct tcttcccatt
    14761 tgcggataac gtggaagaaa tcgccaaagc aggaattaag gccatcatcc agcctggtgg
    14821 ctctgtccgt gaccaagaat ccatcgaagc agcggataaa tacggcttga ctatggtctt
    14881 tacaggtgtg agacatttta gacattaaga agataaaagg gaagaaaaca gtttctttcc
    14941 ttttttggct taaaatgcta actgaaacaa gattaaaacg aacttttttg atataatgtt
    15001 ggtaaataat tcgcaaaaga ggttgaggaa tgaaactgct tgttgtcggt tctggtggtc
    15061 gtgagcatgc gattgctaaa aagttacttg aatcaaaaga cgtggaaaaa gtctttgtag
    15121 ctcctgggaa tgatgggatg actctggatg gtttggaatt ggtaaatatc tctatttccg
    15181 aacattctaa attgattgac ttcgcaaaga ccaatgatgt tgcttggacc tttatcggtc
    15241 cagatgatgc ccttgctgct ggtatcgtgg atgattttaa ccaagctggg cttaaggcct
    15301 ttggtccgac tagggctgca gcggagctgg agtggtccaa ggattttgcc aaggaaatca
    15361 tggtcaaata tggtgtttcg acagcagcct atggcacatt ttcagatttc gaggaagcaa
    15421 aggcctatat cgaaaagcat ggtgcgccta tcgtagtcaa ggcggatggc ttggcgcttg
    15481 ggaagggtgt cgtcgtttct gagacggttg agcaagcggt cgaagccgct catgagatgc
    15541 ttttggacaa taaatttggt gactcaggtg cgcgcgtggt tattgaggaa ttctttgaag
    15601 gagaggaatt ttcactcttt gcctttgtca atggtgataa gttctacatc atgccaacgg
    15661 ctcaggacca caaacgtgcc tatgatggcg acaaagggcc taacacgggt ggtatgggtg
    15721 cctatgcgcc agttccacac ttaccacaga gtgtagttga tacagcggtt gacaccattg
    15781 tcaagccagt tctagaaggg atgattaaag aaggtcgccc ttatctggga gttctttacg
    15841 cagggcttat cctgacagct gatggaccga aagtcattga gttcaacgct cggttcggag
    15901 atccagaaac tcagattatc ttgcctcgct taacctctga ctttgctcaa aatatcacag
    15961 atatcctgga tagcaaggag ccaaatatca cgtggacgga caagggtgtg actctgggtg
    16021 tggttgtcgc atccaagggc tacccgctaa attattcaaa gggtgttgag ttgccagtca
    16081 aaaccgatgg cgacatcatt acctactatg caggggctaa gtttgcggaa aatagcagag
    16141 cactgctctc aaacggcgga cgagtttata tgctcgttac cacagcagat accgtcaaag
    16201 aagcccaagc cagcatctac caagaactat cccaacaaaa aatagaagga ctcttctacc
    16261 gaacagatat cggaagcaag gcaattaagt aaagatataa gaataacgcg ccgtagtcgc
    16321 caaacacgat aatggtcgtc gtggtgaaaa gaccagaaca gtgaatgttc tggtcagggg
    16381 gaaacttgga gaccgtaggc tcaaagttta ggaatgaaac cgaaggtttg cttccgcctc
    16441 catcacctaa gaccattatc aaaaagaaaa ataaaaattc acaaaatacg ttaatgatcg
    16501 tatggtttgc gagcgttagc gagctaatat agaacaatca ccgccgttgt gaaagaacga
    16561 ttggatgata atccaatcgt tcagggaaat tggaagacct tgggtttcca atttaggcat
    16621 gagacacctt tggtggctgc tgccgtccct cacaagctaa ggtgattgtt gaaaaagagg
    16681 aaaaaggaga agaaatgaaa ccagtaattt ccatcatcat gggctcaaaa tccgactggg
    16741 caaccatgca aaaaacagca gaagtcctag accgcttcgg tgtagcctac gaaaagaaag
    16801 ttgtttccgc acaccgcaca ccagacctca tgttcaaaca tgcagaagaa gcccgtagtc
    16861 gtggcatcaa gatcatcatc gcaggtgctg gtggcgcagc gcatttgcca ggcatggtag
    16921 ctgccaaaac aacccttcca gtcattggtg tgccagtcaa gtctcgtgct cttagtggag
    16981 tggattcact ctattctatc gttcagatgc cgggtggggt gcctgttgcg accatggcta
    17041 tcggtgaagc tggagcgact aacgcagctc tctttgccct ccgtctcctc tctgtagaag
    17101 ataagtccat tgcggatgca cttgccaact ttgctgaaga acaaggaaaa atcgcagagg
    17161 agtcgtcaaa tgagctcatc taaaacaatc ggaattatcg gtggcggtca actgggtcag
    17221 atgatggcca tttctgctat ctacatgggc cacaaggtta tcgcgctgga tcctgcggcg
    17281 gattgcccgg cctctcgcgt ggcggaaatc attgtggcac cttataacga tgtggacgcc
    17341 ctccgtcagt tggcagaccg ttgcgatgtc ctcacttatg agtttgaaaa tgtcgacgct
    17401 gacggtttgg atgccgttat caaggatgga caactccctc aaggaacaga tctgctccgc
    17461 atttcgcaaa atcgtatttt tgaaaaggac tttttgtcaa acaaggctca agtcactgtg
    17521 gcaccctaca aggtcgtgac ttctagccta gacttggcag atatcgactt gtcgaaaaac
    17581 tatgtcctca agactgcgac tggtggctac gatggtcatg gacaaaaggt tattcgttca
    17641 gaagcagact tggaagcagc ctatgcgcta gcagactcag cagactgcgt cttggaagaa
    17701 tttgtcaact ttgaccttga gatttctgtc atcgtgtcag gaaatggcaa ggaggtgacg
    17761 tttttcccag ttcaggaaaa tatccaccgc aacaatatcc tgtctaagac catcgtacca
    17821 gcccgcattt ctgaaagtct agcagacaag gctaaagcta tggcagtgcg aatcgcagaa
    17881 caactcaact tgtctggaac tctctgtgtg gaaatgtttg cgactgatga tgacgttatt
    17941 gtcaatgaaa tcgccccacg accacataac tctgggcact attctattga agcctgtgat
    18001 ttctctcagt ttgacaccca tattctgggt gttctcggag caccattacc agtcatcaaa
    18061 ctccatgcgc cagccgttat gcttaatgtc ctcggtcagc atgtcgaggc tgctgagcaa
    18121 tatgtgacag aaaattcaag cgcccacctc cacatgtatg gtaaaataga agcgaagcac
    18181 aaccgcaaga tgggacatgt gaccttgttt agtgatgtac cggatagtgt ggatgagctt
    18241 ggggaaggga ttgattttta ggacaagtct atgatacaaa ttatcgttaa tacatttatt
    18301 gaaaaggata agactggagc agttgttgaa gtgttgtatg ccagtgctga ccaagataag
    18361 gtacaagcta aatatgaaga actagctgca caataccccg aaaattattt agctatctat
    18421 gatgtaccgc tggatacgga tttgaataca ctagatcatt acccgtctgt gtttattgaa
    18481 aaagaggagt ttgagtagaa atcttggttt acctagatag cttattccca acagcttaag
    18541 aagaaaggaa aaattaacac atgatcaacc gttactctcg ccctgagatg gcgaatattt
    18601 ggagtgaaga aaataaatac cgtgcttggc ttgaggtgga aatcctctct gacgaggcat
    18661 gggctgagtt gggggaaatc cctaaggaag atgtggcttt gattcgcaag aaggcggact
    18721 ttgacatcga ccgtattttg gaaattgagc aggagacgcg ccacgatgtg gtggctttca
    18781 cgcgtgcggt ttctgagact cttggtgaag agcgcaagtg ggttcactat gggttaactt
    18841 ctaccgacgt ggtggatact gcttatggtt acctctacaa gcaggccaac gacatcatcc
    18901 gtcgtgacct tgaaaacttc actaatatca tcgctgacaa ggccaaggag cacaagttca
    18961 ccatcatgat ggggcgtact catggtgtgc acgctgagcc gacaaccttt ggtcttaaat
    19021 tggcaacttg gtacagcgaa atgaaacgca atatcgagcg tttcgagcat gcagctgctg
    19081 gtgtagaagc tggtaagatt tctggtgcgg ttgggaactt tgccaatatc ccaccatttg
    19141 tagaggagta tgtctgcgat aaacttggca tccgtgccca agaaatctct acacaagtcc
    19201 ttcctcgtga ccttcacgct gagtactttg cggttcttgc cagcattgcg acttcaatcg
    19261 aacgtatggc gactgagatt cgtggtctac aaaaatctga gcaacgcgaa gtagaagagt
    19321 tctttgctaa agggcaaaaa gggtcttcag caatgcctca caaacgcaac ccaatcggtt
    19381 ctgaaaatat gactggtctg gcgcgtgtca ttcgtggtca catgattacg gcttatgaaa
    19441 acgtcgctct ctggcacgaa cgcgatattt ctcactcatc agctgagcgt atcatcacac
    19501 cagatacgac cattttgatt gactacatgc tcaaccgttt tggaaatatc gtcaagaact
    19561 tgacagtctt cccagaaaat atgatccgaa acatgaactc gacttttggt cttatcttta
    19621 gccaacgggc tatgttgaca ttgattgaaa aaggcatgac ccgtgagcaa gcctatgact
    19681 tggtgcaacc aaaaacagcc tactcttggg acaaccaagt agactttaaa ccacttcttg
    19741 aggcagattc agaagtaaca tcacgtctca ctcaagaaga aatcgatgaa atcttcaacc
    19801 cagtttatta caccaaacga gtggatgata tctttgaacg tcttggacta ggtgattaat
    19861 taaaaaataa acagcgagct tcaatctcgc tgtttatttt ttatcgaaaa gacttagtct
    19921 tcttttcttt tagtgagtcc ataggctgct agtgtggcca tgagtcctgc gactactagt
    19981 cctgcagaat cgtgagttcc tgtttcagga agttttttct ctattaccac aggagctgga
    20041 tcttgaggaa gagctttgct ttcctcagca ggagcagttg atggagctgg ttggcttggg
    20101 atttctagtt ttggtttttc ttcagcaata gcggcttgtc cgttttcatc gcctacatgt
    20161 gttaccatag ttccgacttc gactatttga gtaacggctt cctgtgctac gacactattt
    20221 acaagtgttt tcacttcctt accatcggca gaagtgctca cagagtagaa gttgctacga
    20281 tgtccattga cgcccttagt aatgacttgt gtttttcctt tgagtaagag tggattttca
    20341 cgagtcactg tggtaaatgg aatttcttct ttttggatat ccagtctagg ttttacctca
    20401 gtagttggtg caagaccact ttcatcaccc ttgtgagtta caggagcgcc aacttcaacc
    20461 acttggttta taacttcttt ggttacctgg ctatcaagga ctgtttctgt tgtttttcca
    20521 ttttcagtga gtacagagat gtaatgagtt cgctcacctt tgactcctgc tgtgataata
    20581 ttttcctgac cagctgggag gttaggattt tctttcttga taacttcaaa tggaatttct
    20641 tcagttcttg tgatgagttc tggtctggtt tcaacattgg cagccacttc attttcatcc
    20701 aggcttcctg aatgagttgc agctggtttg aggccttgaa gagcggcttt taggttggct
    20761 acaagtgtgt caagctcagc ttgtttatta cggttgaggt tgtaatttag agctgtttta
    20821 gctgcgtcaa gggcctcaag actttcttta ctatatcctt ctaagtttgt aggaatttta
    20881 gctaattctt cgcggagagc attataatta gcacggaagt agtctttgtt gtggtctgca
    20941 aaggcagtca tgagttcaaa gatttcctct tccttgtatt cagcgcttgg tctatctgcc
    21001 cagattgaaa gcatacttcc gactgttgga agatctactt caggatattt ggtagaagct
    21061 agttgattga atggtgtttt tccagtattc tcaatagctt tcttgaggaa accaccacca
    21121 tcttctggtt tttgaccaag aatgtagtac cagtcaccgt tggtattcaa gaatttatag
    21181 cctttgcttg ctaggtattg aggtgatgcg aggttatatc cccaccagcc tttagaccag
    21241 taagaaatca agacatcttt gtcaaactga acatcgtcct tgtcttcata gtagaagcca
    21301 tcgttgaagg ccattggttg aagccctctt tctttggcca tagctgcgag ggtgttggca
    21361 tattcggcaa atttgccata gagttgatac cacttgaggt agtaccagcc ttgggcacta
    21421 gtcgcatcgt tggcgtattc gtcagtacca aagttgaaaa tctttgtttt acctgcaaag
    21481 aagtccatgt atttaccgat gagggctttt acaaagttca tcgcttcttc gtttttcaag
    21541 tccatagttg tttttgaaac tttatcaaag tgggcttgag gatttttaat acctaatttt
    21601 tccatggcaa ccagcatagc atccatgtga cctggactgt taatagctgg gatgagaccg
    21661 atgtccttag atttagcgta ttcaattagc tctgttactt ctgcctgtgt tagtgcagta
    21721 ccgtttggat cgtcgtagta agctttagtt ccttcgataa tagctttttt aacgtcatca
    21781 ctagcatagg tttttccgtt ggcagtaatg gtcatatcat cgagtagaaa gcgaagtccg
    21841 tcatttccta gaaggagatg gacatcagaa tatccgagct cactggcctt gtctacgatg
    21901 cgtttgagct ggttcagagt aaagtatttg cgtccagcat cgattgagat taccttgttt
    21961 ttggcaagtt tttcaacctc acgtttagct tcttcttctt tttgagcttc aggcgtgagg
    22021 gtcaagttgt tgacagtttc ttgaagttta gcaatggctt gatcaatcgt atcttgttgg
    22081 gcacggctaa ggttgctatc gagagagcga atagcttttt cagcttcttt tacggccgcg
    22141 acgctttctg cagtataacg gttcaggtct tttggtacct cgttaagtgt ttgctctgca
    22201 gattcataat cagctgcgaa gtattcagcg ttggcatttg caaaatgacg catgagtttg
    22261 aagaggcgtg atggtgaata acgtgcagat ggagtgtcag cccaagcagc taccatacta
    22321 ccgatgattg ggatatcagc tccttctgtt tttggtacag aagtgattgg tgtgttttta
    22381 ataccattga gcccctgatc gagattgtac cagccttggc catcagcgtt tcgtccaaga
    22441 acgtagtacc aagcatcatt ggtattaagg atttggtgac ctttttcagc tagtagttta
    22501 gaagaagcga catcgtagcc tccccaacca ccagtccaca tagaaacgat gatgtctttg
    22561 tcaaaactac caaagcttgt gtcgctattg tagtagatac cgtcgttaaa ggccattggt
    22621 ttgagaccgt gcgattttac aatacgagcg aggtcattgg cgtaggcaat aaatttttca
    22681 tagcctttta cagggtagcc ttcgtttgga tagtatttat cagcttgaag cacactccaa
    22741 cctttagcat ctgtcgcatc attggcatat tcatcaagtc cgatgttgaa gatttcagtc
    22801 tttttcgcga aataagcagc atacttgtcg ataagggctt ttgtaaaagc gacagcttgt
    22861 tcgttgtcaa gattgacagt acgggctgat tccttcccaa aatagctaaa gttagggttt
    22921 tggattccca attctttcat ggcattgaga atcgcatcca tgtgaccagg actatttact
    22981 gtcggaatga gaccgatacc tttatctttg gcatagttaa tcagatctgt catttgactt
    23041 tctgttaagt gattgccgtt tggatcgttg taataatcat ttgtaccttt ttcaatggcg
    23101 cgtttgacat cgtcactggc ataggtcttg ccgttagctg tgatgctcat atcgtccaac
    23161 atgaaacgga gtccatcatt tccgactaat aggtgtaaat cagtgtagcc ataatgtttc
    23221 gctttatcga tgatttcctt gagctgttct ggtgagaaat atttacgtcc agcatcaata
    23281 gaaacaattt tctttttcgc tagtttttca tttacagttg cagcacgttc ctttcctgcc
    23341 tctgtttccg gtttgtcatc ctctgctttc gcttcatctt ttttagctgg tttatccttg
    23401 tcagtcttgt ctgtatttga ctctttagaa tcaacctctt tcgcttcttc ctttttaggg
    23461 ctagcttctt ctgccttttt attagcagtt tctttttcag cagaagttgg agttaccact
    23521 tctgctttat cactaggagt tgaactaact tcctcttgtg gtttttcttc tgtttttgga
    23581 agactagcta ccttatcagt agctggagtt tctgtttcta cagtttttgg agcttctggt
    23641 tgaagctctg ctttaggtgt ttcctcagtc cgattttcgg atgattgagg ggaatcagaa
    23701 accgtatgga tggtcggttg gttttctgta gtagtaggag taactccatc ggctgcaaca
    23761 gtctgtgctt ggaaggcaaa tccaattaga acagaagctg ctcctacagc gtatttacga
    23821 atagaaaaac gctgttgttt ttcatgtttc attgcaaaac ctcctgattg cattgttata
    23881 ttgatagcga ttatataaat caacgccttt attttatttc ttatattaac gagagtcaag
    23941 aggagatgac aaaaaactat aataagtata aaaaaatata aaatttaaac ttaagatttc
    24001 agattggtcg gaaaaaatac gtatatatat ctagtataat ttttggttct atttctataa
    24061 aatattccac aaattataga attttccaaa aataggtaag cgctaccttt ttggtgtggt
    24121 ataataagca tagaaaaagc ccaagcgatt agctcaggct ttcttcttag tgatcacggt
    24181 cacatgagat aaatttaatc ttgtagtaat cagatcgttt gtaagtttca ctgtattcta
    24241 aaacttggcc agttgattcg agtttggtga ttttagtttg taggacagta gggaattgtt
    24301 catcgactcc gaggactgaa gccgcatgtt ctggagttgg aaagactatt tcgttgattt
    24361 cttcaaagtg ttcatcattc atgtgaatgt ggtagtctaa cttgaaacga ttatagatag
    24421 aactatagta ttcaaggttt ggataatttg cgttgatata ttgttctggg atgtaggatg
    24481 tatggtagat ataaacgaca ccgtttgatt cgcggatacg ttcaatcttg tagtagaatt
    24541 gatcgccgcg tagacccaat ttttccaagt aaacaagctt gtttccgcgt tcaattgaaa
    24601 gaacagttac cttatcatct ttagcattga agagttcaat atctgaaaac tctacaagct
    24661 tgtgtttgcg tgcacgtgaa acgaaggttc cttttccttg ttggcggaca atatagccat
    24721 ctttggcaag gtcgtttaag gcgcgaacaa ctgtgataga gctgacatcg tacattgaaa
    24781 tgagttctgc ttcagtgtaa aatttatctc cactgctaaa ctgcccagag atgattttat
    24841 tttttaattc gtcttttatg tattgatatt tgggaattgc catattttta cctctatttt
    24901 ccttctccat aggaaatttt accataaaag cgaaaaaaat agtagtcttt tgaataaaaa
    24961 attagaataa tagtttgaaa aattaagcga tatagggatt gctcatattt tatcaatgta
    25021 ttctatacaa aattatttta ggtcccatat tccgaattta aagagcgttt gaaatgggtc
    25081 taaaaatgtt tgaaactaat tgaatgtgtg tataatagta aaaatgcagt aaatatcccg
    25141 acaatttcta ttgacaattc aaacagattg gtttataatt aatataacaa caaatgaaag
    25201 cgcaaacttt cgcggtcgga aggtagtttt atgacacgat ttgagatacg agatgatttc
    25261 tatctcgatg gaaaatcatt taagatttta tctggtgcca ttcattattt tagggttcct
    25321 ccagaggatt ggtatcattc gctctataac ttgaaggctc ttggttttaa tacggtagag
    25381 acttatgttg cttggaattt acacgagcct cgtgaaggtg agtttcattt tgaaggtgat
    25441 ctggatttag agaaatttct ccaaatagcg caggatttgg gtctctacgc aattgtgcgt
    25501 ccgtctccat ttatctgtgc ggaatgggaa ttcggtggct taccagcttg gctcttgacc
    25561 aagaacatgc gaattcgctc atccgaccca gtatatatcg aggcagttgg tcgctactat
    25621 gatcagttat tgccaagact ggtgcctcgt ttgttggaca atggtggcaa tattctcatg
    25681 atgcaggttg aaaatgagta tggttcttac ggagaagata aggcttacct gagagcgatt
    25741 cgacagctaa tggaagagtg tggcgtaacc tgtcccctct ttacatcaga tggtccatgg
    25801 cgagctactc tgaaagctgg aaccttaatt gaagaggacc tctttgtaac aggaaacttt
    25861 ggttctaagg caccttacaa cttttcgcag atgcaggaat tctttgatga acatggtaag
    25921 aaatggccac tcatgtgtat ggagttctgg gatggttggt tcaatcgctg gaaagaaccg
    25981 attatcacac gggatcctaa ggaattggca gatgcagttc gagaggtttt ggaacaaggc
    26041 tctatcaatc tttacatgtt ccacggtggt acaaactttg gtttcatgaa tggttgctca
    26101 gctcgaggaa ctttggacct gccacaagtt acgtcttatg attacgatgc ccttctggat
    26161 gaagaaggaa atccaactgc taaatatctt gcagtcaaga agatgatggc aacacatttt
    26221 tcagagtatc cgcagttgga accactctac aaagagagta tggagttgga tgctattcca
    26281 ctagttgaaa aagtttcttt gtttgaaacc ttagatagct tgtcaagtcc tgtagaaagt
    26341 ctctatcctc aaaagatgga ggagctggga caaagttatg gctacctact ttatcgaaca
    26401 gaaacaaact gggatgcaga agaagaaaga cttcgtatca ttgatggtcg agatagggcc
    26461 cagctgtatg tcgatggtca gtgggttaaa actcaatatc agacagagat tggggaagat
    26521 attttttatc aaggtaaaaa gaaagggcta tctaggttag atatcttgat agaaaatatg
    26581 gggcgtgtca actatgggca taagttctta gcggatacgc aacgtaaggg aattcggaca
    26641 ggggtctgta aggatctgca tttcttacta aactggaaac actatccact cccactagac
    26701 aatcctgaga aaattgattt ttcaaaagga tggactcaag gacaaccagc cttttacgct
    26761 tatgacttta cagtcgaaga gccaaaagat acttacctag acttgtctga gtttggtaag
    26821 ggggttgcct ttgtcaatgg gcagaatcta ggacgttttt ggaacgttgg cccaactctc
    26881 tcactttata tccctcatag ctatctcaag gaaggtgcca accgcatcat tatctttgaa
    26941 acagaaggtc aatataaaga agagattcat ttaactcgta aacctacact aaaacatata
    27001 aagggggaaa acttatgaca attgtaggat gccgtattga tggacgtttg atccacggac
    27061 aagtagccaa tctttgggct ggaaaactaa atgtttcacg cattatggtt gtagacgacg
    27121 aagttgtcaa caacgatatt gaaaagagtg gtttgaaact tgcgacacca ccaggtgtga
    27181 aattgagtat tttgccagtt gagaaagctg cagccaatat tcttgctggt aaatacgata
    27241 gccaacgtct ctttatcgtg gctcgtaaac cagaccgctt ccttggtttg gtagaagcag
    27301 gtgtaccact tgaaaccctt aatgttggga atatgtctca aacaccagaa acacgttcta
    27361 ttacacgttc tatcaacgta gtagacaagg atgtggaaga cttccacaaa ctggcagaaa
    27421 aaggtgttaa acttactgct cagatggttc caaatgatcc aatttcagac tttttgagct
    27481 tattaaaata ggaaaaaaat ttttaggagg tcattgttat gatacaatgg tggcaaattt
    27541 tacttctcac tttgtactca gcttatcaaa tctgtgatga gttgacgatc gtttcatctg
    27601 caggttctcc tgtatttgct ggtttcatta ctggtttaat catgggagat gtgactactg
    27661 gtttacttat cggtggtaac ttgcaactgt tcgttcttgg ggttggtacc ttcggtggtg
    27721 cttctcgtat cgacgcaact tctggtgcgg ttcttgcgac agccttctct gtttcacaag
    27781 gaattgatgc accgcttgcc attactacaa tcgctgtacc agtagcagct ctcttgactt
    27841 acttcgacgt tcttggtcgt atgactacta ccttcttcgc tcaccgtgtg gatgctgcaa
    27901 tcgaacgctt tgactataaa ggtattgaac gcaactactt gcttggtgcg attccgtggg
    27961 ctctatctcg tgcccttcca gtcttctttg cccttgcttt tggtggtgcc tttgtacaat
    28021 cagtagtaga cttcgttgaa gcctacaaat gggttgcaga tggcttgaca ctcgcaggac
    28081 gtatgcttcc aggtcttgga tttgcaatct tgcttcgtta ccttccagtt aaacgtaacc
    28141 ttcactacct tgctatggga tttggtttga cagctatgtt gactgttctt tactcatatg
    28201 taacaggtct tggtggcgct gttgctggta tcgtaggtac tcttcctgct gaagttgctg
    28261 aaaaaattgg tttcgtgaac aacttcaaag gtttgtctat gattggtatt tctatcgtag
    28321 gtattttcct tgcagtgctt cacttcaaaa atagccaaaa agtagctgta gcagcacctt
    28381 ctacaccatc agaaagtggg gaaatcgaag atgacgaatt ctaattacaa acttacaaaa
    28441 gaagatttta atcaaatcaa caaacgtagc ttgtttactt tccaattagg ttggaactac
    28501 gaacgtatgc aagcttctgg ttacctttac atgatcttgc ctcagttgcg taaaatgtat
    28561 ggtgatggaa ctcctgaatt gaaagaaatg atgaaagttc atactcaatt cttcaatact
    28621 tcaccattct tccataccat tatcgctggt tttgaccttg ccatggaaga aaaagatggt
    28681 gtaggttcaa aagacgctgt taacggtatc aagacaggtt tgatgggacc attcgctcct
    28741 cttggggata caatctttgg ttcacttgta cctgctatca tggggtcagt cgcagcaact
    28801 atggctatcg ctggccaacc ttgggggatc ttcctttgga ttgcagttgc agtagcgtat
    28861 gacatcttcc gttggaaaca gttggaattt gcttacaaag aaggggttaa ccttatcaac
    28921 aacatgcaaa gtaccttgac agctttgatt gacgctgcat ctgtacttgg tgtcttcatg
    28981 atgggtgctc ttgtagcaac agtgattaac tttgaaattt cttacaagtt gccaatcggt
    29041 gaaaagatga ttgatttcca agacatcttg aaccaaatct tcccacgttt gcttccagca
    29101 atctttactg cctttatctt ctggttgctt ggtaaaaaag gtatgaactc tactaaagct
    29161 atcggtatta ttatcgtact tgctttggct ctttctgccc ttggtcactt tgcacttgga
    29221 atgtaattcc ttatgactaa atcattaatt ttggtgagcc atggtcgctt ctgtgaggag
    29281 cttagaggta gcacagaaat gattatgggc ccacaagaca acatttacac agtagctctt
    29341 cttccagaag atggcccaga agaatttact gctaaatttg aagctgttat tgaaggattg
    29401 gatgatttcc tagtctttgc ggatcttctc ggtgggacac cttgtaatgt ggtgagtcgc
    29461 ttgatcatgg aaggtcgtga tattgacctt tacgcaggga tgaatcttcc aatggtgatt
    29521 gaatttatca atgcgagcct tacaggcgca gatgcggact acaagagccg tgctgcagaa
    29581 agcattgtga aagttaatga cctgttagcg ggcttcgatg atgacgaaga tgaataatac
    29641 tcttcgaaaa tctcttcaaa ctacgtcaac gtcgccttgc cgtaggtata tgttactgac
    29701 ttcgtcagtc ttatccggca acctcaaaac ggtgttttga gctgacttcg tcagtcttat
    29761 ccggcaacct caaagcagtg ctttgagcag cctgcggcta gtttcctaca gattttagtt
    29821 ggaactcgat tcaattcatg tgacaacgtg aaaatcgtta gagcatttta tatagaatat
    29881 acatgggaat ggagcttact cccattccca tatttaatag aaaaagagga actcaatgct
    29941 acattataca aaagaagact tgctcgaatt gggtgcagaa atcactacgc gtgaaatcta
    30001 ccaacagcct gatgtatgga gagaagcttt tgaattttat caagcaaaac gtgaagaaat
    30061 tgcagccttt ctacaagaaa tcgctgataa acatgactat attaaggtta tcttgacagg
    30121 tgctgggact tctgcttatg tgggagatac cttgctacct tactttaagg aagtctatga
    30181 cgaacgcaaa tggaatttca atgctattgc gacaacagat atcgttgcca aaccagcaac
    30241 ctatttgaaa aaagatgtgg caactgtcct tgtgtctttt gctcgtagtg ggaactcgcc
    30301 tgaaagtgtg gcgactgttg atttggccaa atccttggtg gatgagcttt atcaagtgac
    30361 gattacttgt gcagcagatg gtaaattggc tcttcaagct cacggtgatg accgtaatct
    30421 cttgctcttg caaccagctg tctctaatga tgctggattt gccatgactt ctagctttac
    30481 gtctatgatg ttgacaactc tcttggtctt tgatcctaca gaatttgctg ttaagtctga
    30541 acgttttgaa gttgtatcta gtcttgcccg taaagtttta gacaaggcag aagatgtcaa
    30601 agagctcgtt gatttagact ttaaccgtgt catctatcta ggcgctggtc ctttctttgg
    30661 acttgctcat gaagctcagc tcaagatttt ggaattaact gctggtcaag ttgcgaccat
    30721 gtatgaaagc ccagttggct tccgtcacgg tccaaaatct cttatcaacg acaatacagt
    30781 tgttttggtc tttggtacaa cgacggacta cactcgtaag tacgacttgg acttggttcg
    30841 tgaagttgct ggtgaccaga ttgctcgtcg tgttgtgctt ttgagtgatc aagcttttgg
    30901 tcttgaaaat gtcaaagaag tggtccttgg ttgtggcggt gtcttgaatg atatttaccg
    30961 tgtcttccct tacatcgttt atgcccaact ctttgcccta ttgacttcac tcaaggtaga
    31021 aaataaacca gatacaccgt ctcctacagg tacagtaaac cgtgtagtac aaggtgtcat
    31081 aattcacgaa tatcaaaagt aagacagtgt ttatgaattc ttgacaagag gatttgtaaa
    31141 ttatcagata aaccatagat tgtcagtacg ctttctatgg tttgtttgct tgagagaaat
    31201 agtaaaagga gaacagaatg aaagcataca cagagcgtgt atttggaaat gttgagggtg
    31261 aggatgtctt ggcctatcga tttgagacag acggtggcta ccaacttgag gttatgactt
    31321 atggtgcgac tatcttgcgc tatgtcgcac ctgacaaggc tggaaatttt gccaatgtta
    31381 tcttgggatt tgatgacttt gatagttatg taggcaatag tcccaagcat ggagcaagtg
    31441 taggtcctgt agcgggtcgt attgcaggtg cgacctttga gctcaatggt aagacctatg
    31501 accttgaggt taataatgct agcaactgta atcacagtgg ttcaactggt tgggattcca
    31561 gcttgtttga agttgaagaa gtaagcgatc atggcttgac tctctacaca gagcgtacag
    31621 atgggacagg agggttccct ggaaatctca agatttggat cagttatcac ttggaagaaa
    31681 ctggtgccta tgaaatcagc tacaaggtaa cgaccgatca ggatacgctg gtcaatccaa
    31741 ccaaccacag ctatttcaac ttgtctggtg atttcacgca gacgattgac cgtcatgtct
    31801 tccaactaaa cacagagggc atttactcaa tcgctcctga cggtgttcct gccaaaactc
    31861 cagaagccaa ccgtgatgtg gtcaaacaca tctacaatgg tgccttgttg aaggatatct
    31921 ttgcagaaga agatgagcaa atccagctgg catcaggttt ggatcatcca tttgcccttc
    31981 ctgcaggcca tgacaatgct ggattccttt atgaccaaaa ttcaggtcgc ttcctgcttt
    32041 tcaagacaga agctccttgc tttgtggtct acacagcaaa ctttgtggat gaaagtgtca
    32101 tcataggagg tcagccaatg ctacagcaca atgggattgc tcttgaagcg caagctttac
    32161 cagatgccat tcacagtgac cttaaaggcc aagtcattct taaagctggt caaaccttca
    32221 ccagtaagac acgttatgaa cttgttgtga aataaaaaaa gctggtcaaa aagtctttaa
    32281 aattaaaata acgcatattg tcaggtgatg aaaagtttga taatatgcgt tttattatga
    32341 aatgatttac tttatattat cctgaaatgg tgttattttt gagttatctg gcttgacttt
    32401 cttgatggaa attatataat agttgtaaca atgataatta caactagaaa agaggaccat
    32461 ttatgaccta tgaatacaag agtcacattt atttggcaga gacagcttta aatgtaaagg
    32521 atttggccag tcaaacagcc ttttatcagc aagttattgg tttagaaatc ttatctcaaa
    32581 ctgagacaga gtccattcta ggccttggtg gaaaagtctt ggtacagctg attcaagcac
    32641 aagagagcgg agaagtgagg gaatattatg gtctttacca tttggccatt ctcttgccca
    32701 cacgcaaggc tttagctgat gtcttgaaac acctgacaga tttacaaatt cctcttgtcg
    32761 gcggtgcaga ccatggttac agtgaagcta tttacttgga agatttggag ggaaatggca
    32821 ttgaactcta tcgagataag ccagtttcca catgggatat tcgagaagat ggacgcatta
    32881 tcggagtgac agaggctctt gcggcgcagg acatttatga gttgggggaa agagtagagc
    32941 cctttatcct ggcagaaggt acgagaatgg ggcatattca tctttccgtc aaggatagtc
    33001 gaaagtccag ccagttttat caaaaggtgt tagggctaga ggataaattc agtgtgccta
    33061 gcgctagttg gattgcggct ggagattacc atcatcattt agcagttaac gaatggggag
    33121 gaaaaggtct ggcttcgcgt aagcaaggct taccaggttt agcctactat gtcatcgaag
    33181 tcgcacacaa aaaagaacta ttaacgattg cccaacgagc acaagaagtt gacgcaccaa
    33241 tcaaatggat gacatcgagc caattggaaa tcacagactc agatggcatc gtgacccgta
    33301 ttcgtttagc aaggtaaaat taggaatttt taataagtta taagtattgc tagtttgctt
    33361 tttgaacggt ctttggtaac agaactgcgt gagctggatg ggcgagaatt ttgacaaaga
    33421 agctgattag agatataatg aagaaaaatc gagcaaggaa aaagaaatga caaattcaaa
    33481 gtatattact tgtttgaaac gttcagaggg ccagttgtgt gggattcaaa agatgattga
    33541 aggagatcgt gactgtgctg atattgtgac gcaactgaca gcagtgagat ctagtgtaga
    33601 gcgcgtgatt gagatgataa ttaccgaaaa tcttactgaa tgtatcaatc agccactaga
    33661 tgattctgaa gctcaaaagg aacgcttaga aaaggctatc cgatacttga ttaaacggaa
    33721 ataaatgaat gttttgagac gatatgtgca aaggtctatt aactattaga atagtttaat
    33781 gggagtcaaa agaagttgta aaaaatcttt aaaattaaaa aaacgcatag tatcaggtat
    33841 tgaaatgtac tgaccccaaa aagttagatt ttttctgtct aacttttggg gtgcagttca
    33901 taagaacctt ggtaatatgc gttttattat ggggagattt atacttttcg aaaatctctt
    33961 caaaccaggt cagcttcacc ttgccgtaga tatggttact gacttcgtca gttctatcca
    34021 caacctcaaa acagtgtttt gagctgactt cgtcagttcc atccacaacc ttaaaacagt
    34081 gttttgagct gacttcgtca gttccatcca caaccttaaa acagtgtttt gagcagcctg
    34141 cggctaactt cctagtttgc actttaattt tcattgagta ttacttcatc ttctcatgaa
    34201 attgagtttt tgcccagttc ctcttgatta ttctacttga ccaggccaag cattcatacc
    34261 accttctacg ttggtaacgg tgaggccttg ggagatgaga aattggcagg tagatgcaga
    34321 gcggactcct ccttgacaaa taacatagta ttcatggtca ggtttgagtt ctttgtagcc
    34381 ttgctctaag gtacttaatg gaagattttt ggcacctggt gcatgtcctg cttggaattc
    34441 atgtgcttca cggacatcga taagttctag attttcattt tggtattttc cataaaagtc
    34501 agccatgctg atactagttt ccatattcta ctccttctgg gttaaccatt ttgtatagtg
    34561 aataagcgcc gtcaaggttt tgggcggtaa atcctgcttg cttgaggata ggctctgcga
    34621 tatagctgcg caaaccactg tggcagctga cgatgtaggc ttgttttttg tccagttcat
    34681 cagcttcctc cttgacactt tgtcagtttt tgatacaata gtacaaaatt agaggaggtg
    34741 ggctatgatt cagaaacatg cgattcctat tttagagttt gatgacaatc ctcaggcggt
    34801 tatcatgccc aatcacgagg ggctggactt gcagttgcca aagaagtgtg tttatgcatt
    34861 tttagatgag gagattgacc gctatgcaag ggaagtaggg gcggattgtg tcggcgaatt
    34921 cgtttctgct accaagacct atccagtcta tgtcatcaac tacaagggtg aggaggtctg
    34981 tctggctcag gctcctgttg gctccgctcc agcagcccag tttatggatt ggttgattgg
    35041 ctatggtgtg gagcagatta tctctactgg gacctgtggt gttctagctg atatagagga
    35101 aaatgccttt ctagtccctg ttcgcgctct gcgagatgaa ggagccagtt accactatgt
    35161 ggcaccttct cgttatatgg aaatgcagcc agaggctatt gctgctattg aggaagtttt
    35221 ggaagacaga gggattcctt atgaagaagt catgacctgg acgacagacg gtttttaccg
    35281 agaaacggct gaaaaggtgg cttatcgtaa ggaagaaggc tgtgctgttg tggagatgga
    35341 gtgttctgct cttgcggcag tagctcaatt gcgtggggtt ctctggggtg aattgttgtt
    35401 cacagcagat tctctagcgg acttggacca gtacgacagt cgtgactggg gctcggaagc
    35461 ttttaataag gcgctagaac tgagtttagc aagtgttcac cacctttagt tgtactggca
    35521 aaggatttgt tttatcataa aatgtctagc tcatactttt caaaaatatg tttaaacgag
    35581 gtcaccttcc tcttgtccta agcatgttga ggttgggaaa aatctttaaa atcagaaaaa
    35641 cgtatcatat caggtgatga aaaccttgat actatgcgtt ttatgttggt aagatttaga
    35701 gtgagatgaa atgatactct tcgaaaatct tttcaaacca ggtcagcttc accttgccgt
    35761 aggtatatgt tactgacttc gtcagtctta tccggcaacc tcaaaacggt gttttgagct
    35821 gacttcgtca gttctatttg caacctcaaa acagtgtttt gagcaatctg tgactagctt
    35881 tctaatcgat gccttggttc tcattgccta taatcaaaaa gagaaatttt ctcctgaaaa
    35941 gcatatagag tagctggcgt taaaagctcc tgtcttgctt ttttgaccta tagtcacatc
    36001 tatcaagtat tgttcttgcc taagctatca ataaaaaggt ggcatttttt aggcttggtg
    36061 ttagtagatt ttgccttatc ctatctaagt catttcgaac tttttatggt acaatggaaa
    36121 catgttattc aaattatcta aggaaaaaat agagctaggc ttatctcgtt tatcgccagc
    36181 ccgtcgtatt tttttgagtt ttgccttggt cattttacta ggctctcttc ttttgagctt
    36241 gccctttgtc caagttgaaa gctcacgagc gacttatttt gatcatcttt tcactgctgt
    36301 ctctgcagtc tgtgtgacag gtctctcaac ccttccagta gctcacacct ataatatatg
    36361 gggccaaata atctgtttgc tcttgattca gatcggtggt ctagggctca tgacctttat
    36421 tggggttttc tatatccaga gcaagcaaaa gcttagtctt cgtagccgtg caactattca
    36481 ggatagtttt agttatggag aaactcgatc tttgagaaag tttgtctatt ctatttttct
    36541 cacgaccttt ttggttgaga gcttgggagc tattttgctt agttttcgcc ttattcctca
    36601 acttggctgg ggacgtggtc tttttagttc catttttcta gcgatctcag ccttctgtaa
    36661 tgccggtttt gataatttag ggagcaccag tttatttgct tttcagaccg atttactggt
    36721 caatctggtg attgcaggct tgattattac aggcggcctt ggttttatgg tctggtttga
    36781 tttggctggt catgtaggaa gaaagaaaaa aggacgtctg cactttcata cgaagcttgt
    36841 actattgttg actataggtt tgttgttatt tggaacggca actactctct ttcttgagtg
    36901 gaacaatgct ggaacgattg gcaatctccc tgttgccgat aaggttttag ttagcttttt
    36961 tcaaacagtg acgatgcgaa cagctggctt ttctacgata gattatactc aggctcatcc
    37021 tgtgactctt ttgatttata tcttacagat gtttctaggt ggggcacctg gaggaacagc
    37081 tgggggactc aagattacga cattttttgt cctcttggtc tttgcacgaa gtgagcttct
    37141 aggcttgcct catgccaatg ttgcgagacg aacgattgcg ccgcgaacgg ttcaaaaatc
    37201 ctttagtgtc tttattatct ttttgatgag cttcttgata ggattgattc tgctagggat
    37261 aacagccaaa ggcaatcctc cctttatcca cctcatattt gaaaccattt cagctcttag
    37321 tacagttggt gtaacggcaa atctgactcc tgaccttggg aaattggctc tcagtgttat
    37381 catgccactt atgtttatgg gacgaattgg tcccttgacc ttgtttgtta gcttggcaga
    37441 ttaccatcca gaaaagaaag atatgattca ctatatgaaa gcagatatta gtattggtta
    37501 agaaaggaaa gagcatgtca gatcgtacga ttggaatttt gggcttggga atttttggga
    37561 gcagtgtcct agctgcccta gccaagcagg atatgaatat tatcgctatt gatgaccacg
    37621 cagagcgcat caatcagttt gagccagttt tggcgcgtgg agtgattggt gacatcacag
    37681 atgaagaatt attgagatca gcagggattg atacctgcga taccgttgta gtcgcgacag
    37741 gtgaaaatct ggagtcgagt gtgcttgcgg ttatgcactg taagagtttg ggggtaccga
    37801 ctgttattgc taaggtcaaa agtcagaccg ctaagaaagt gctagaaaag attggagctg
    37861 actcggttat ctcgccagag tatgaaatgg ggcagtctct agcacagacc attcttttcc
    37921 ataatagtgt tgatgtcttt cagttggata aaaatgtgtc tatcgtggag atgaaaattc
    37981 ctcagtcttg ggcaggtcaa agtctgagta aattagacct ccgtggcaaa tacaatctga
    38041 atattttggg tttccgagag caggaaaatt ccccattgga tgttgaattt ggaccagatg
    38101 acctcttgaa agcagatacc tatattttgg cagtcatcaa caaccagtat ttggataccc
    38161 tagtagcatt gaattcgtaa agagggatga cccctctttt ttgatgccca agatggcaaa
    38221 tagagacaga agccccttgt cttctagtaa aagttcttca aaggctggac tttatggtaa
    38281 aatagaagga agtgacaaga gagagtaata ctcaatgaaa atcaaagatc aaactaggaa
    38341 actagctgcg ggctgctcaa aacactgttt tgaggttgtg gatagaactg acgaagtcag
    38401 ctcaaaacac tgttttgagg ttgcagatag aactgacgaa gtcagtaaca tctatacggc
    38461 aaggcgacgt tgacgcggtt tgaagagatt ttcgaagagt ataagaaaaa atcagtcccc
    38521 taaaggagca gattatgaag ttattgtcta tcgccatttc tagctataat gcagcagcct
    38581 atcttcatta ctgtgtggag tcgctagtga ttggtggtga gcaagttggg attttgatta
    38641 tcaatgacgg gtctcaggat cagactcagg aaatcgctga gtgtttagct agcaagtatc
    38701 ctaatatcgt tagagccatc tatcaggaaa ataaatgcca tggcggtgcg gtcaatcgtg
    38761 gcttggcaga ggcttctggg cgctatttta aagtagttga cagtgatgac tgggtggatc
    38821 ctcgtgccta cttgaaaatt cttgaaacct tgcaggaact tgagagcaag ggtcaagagg
    38881 tggatgcctt tgtgaccaat tttgtctatg aaaaggaagg tcagtctcgt aagaagagta
    38941 tgagttacga gtcagtcttg cctgttcggc agatttttga ctaggaccag gtcggaaatt
    39001 tctccaaagg ccagtatatc atgatacact cgctgattta tcggacagat ttgttgcgtg
    39061 ctagccagtt ctaactgcct gaacatactt tttatgtcga tgatctcttt gtctttacgc
    39121 cccttcagca ggtcaagacc atgtactatc tgcctgtcga tttctatcgt tatttgattg
    39181 ggcgtgagga ccagtctgtc aatgagcaag tgatgattaa gcgcattgac cagcaactca
    39241 aggtcaatcg actcttggta gaccagcttg atttgtccca agtgagtcat cctaaaatgc
    39301 gagaatatct gctgaatcat attgaaatca cgacggtgat ttccagtacc ctgctcaacc
    39361 gatctgaaac agcggagcat ctggcaaaaa aacgccaatt gtggacctat attcagcaga
    39421 aaaatccaga agtctttcag gctattcgta agaccatgtt gagccgtttg accaaacatt
    39481 ctgtcttgcc agatcgcaaa ctgtccaatg tcgtctatca aatcaccaaa tctgtttatg
    39541 gatttaatta atataagtgt tttataagag ggatttaaga aaaattttaa ctttttctta
    39601 gtccttttta atttcaggag attatactag agtcatcaaa taaagaaaga ctctaaggag
    39661 aatcctatga aattcaatcc aaatcaaaga tatactcgtt ggtctattcg ccgtctcagt
    39721 gtcggtgttg cctcagttgt tgtggctagt ggcttctttg tcctagttgg tcagccaagt
    39781 tctgtacgtg ccgatgtggt caatccgacc ccaggtcaag tcttacctga agagacatcg
    39841 ggaacgaaag agggtgactt atcagaaaaa ccaggagaca ccgttctcac tcaagcgaaa
    39901 cctgagggcg ttactggaaa tacgaattca cttccgacac ctacagaaag aactgaagtg
    39961 agcgaggaaa caaactcttc tagtctggat acactttttg aaaaagatga agaagctcaa
    40021 aaaaatccag agctaacaga tgtcttaaaa gaaactgtag atacagctga tgtggatggg
    40081 acacaagcaa gtccagcaga aactactcct gaacaagtaa aaggtggagt gaaagaaaat
    40141 acaaaagaca gcatcgatgt tcctgctgct tatcttgaaa aagctgaagg gaaaggtcct
    40201 ttcactgccg gtgtaaacca agtaattcct tatgaactat tcgctggtga tggtatgtta
    40261 actcgtctat tactaaaagc ttcggataat gctccttggt ctgacaatgg tactgctaaa
    40321 aatcctgctt tacctcctct tgaaggatta acaaaaggga aatacttcta tgaagtagac
    40381 ttaaatggca atactgttgg taaacaaggt caagctttaa ttgatcaact tcgcgctaat
    40441 ggtactcaaa cttataaagc tactgttaaa gtttacggaa ataaagacgg taaagctgac
    40501 ttgactaatc tagttgctac taaaaatgta gacatcaaca tcaatggatt agttgctaaa
    40561 gaaactgtcg aaaaagctgt ta
//
LOCUS       DAVAZT010000014        37815 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVAZT010000014 DAVAZT010000000
VERSION     DAVAZT010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37815
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.014"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(320..517)
                     /locus_tag="VQT45_000666"
     CDS             complement(320..517)
                     /locus_tag="VQT45_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2359023.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
     gene            complement(502..780)
                     /locus_tag="VQT45_000667"
     CDS             complement(502..780)
                     /locus_tag="VQT45_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HET2359024.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTRFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            complement(819..1604)
                     /locus_tag="VQT45_000668"
     CDS             complement(819..1604)
                     /locus_tag="VQT45_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2359025.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            complement(1606..2424)
                     /locus_tag="VQT45_000669"
     CDS             complement(1606..2424)
                     /locus_tag="VQT45_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HET2359026.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVIYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            complement(2426..3418)
                     /locus_tag="VQT45_000670"
     CDS             complement(2426..3418)
                     /locus_tag="VQT45_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2359027.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYDGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            complement(4463..4681)
                     /locus_tag="VQT45_000671"
     CDS             complement(4463..4681)
                     /locus_tag="VQT45_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HET2359028.1"
                     /translation="MKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVS
                     AIDSSEAMLLPTINVLELLDKSQPFEEE"
     gene            4839..4916
                     /locus_tag="VQT45_000672"
                     /pseudo
     CDS             4839..4916
                     /locus_tag="VQT45_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(5577..6266)
                     /gene="rplA"
                     /locus_tag="VQT45_000673"
     CDS             complement(5577..6266)
                     /gene="rplA"
                     /locus_tag="VQT45_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HET2359029.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMGLVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(6473..6898)
                     /gene="rplK"
                     /locus_tag="VQT45_000674"
     CDS             complement(6473..6898)
                     /gene="rplK"
                     /locus_tag="VQT45_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HET2359030.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAVRMIEGTARSMGFTVID"
     gene            complement(7021..7737)
                     /locus_tag="VQT45_000675"
     CDS             complement(7021..7737)
                     /locus_tag="VQT45_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HET2359031.1"
                     /translation="MKKRYLVLTALLALSLAACSQEKAKNEDGAAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     VIGTNGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYFGFEGGDYVD"
     gene            complement(7740..8210)
                     /locus_tag="VQT45_000676"
     CDS             complement(7740..8210)
                     /locus_tag="VQT45_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET2359032.1"
                     /translation="MCLICQRIELIKKGENPYFVKELETGYLVIGDHQYFAGYSLFLA
                     KEHVSELHHLEKKTRIRFLEEMSVVQEAVAKAFAAEKMNIELLGNGDAHLHWHLFPRR
                     RGDMNGYGLNGRGPVWWIPFEEMTAEICQSKPDEIKRLVERLSSEVDKLLEIKE"
     gene            complement(8212..9249)
                     /locus_tag="VQT45_000677"
     CDS             complement(8212..9249)
                     /locus_tag="VQT45_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HET2359033.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVLGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAMLLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTNEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLKSALVD"
     gene            complement(9347..10672)
                     /gene="brnQ"
                     /locus_tag="VQT45_000678"
     CDS             complement(9347..10672)
                     /gene="brnQ"
                     /locus_tag="VQT45_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HET2359034.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(10843..10935)
                     /locus_tag="VQT45_000679"
     CDS             complement(10843..10935)
                     /locus_tag="VQT45_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2359035.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(10978..11130)
                     /locus_tag="VQT45_000680"
     CDS             complement(10978..11130)
                     /locus_tag="VQT45_000680"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2359036.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LADSYD"
     gene            complement(11290..11868)
                     /locus_tag="VQT45_000681"
     CDS             complement(11290..11868)
                     /locus_tag="VQT45_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HET2359037.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPCT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(11922..13322)
                     /gene="pepV"
                     /locus_tag="VQT45_000682"
     CDS             complement(11922..13322)
                     /gene="pepV"
                     /locus_tag="VQT45_000682"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HET2359038.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLTDLQAKLDAFVAEHKLRGELQEEAGQYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(13335..13940)
                     /locus_tag="VQT45_000683"
     CDS             complement(13335..13940)
                     /locus_tag="VQT45_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HET2359039.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDLKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            14111..14911
                     /locus_tag="VQT45_000684"
     CDS             14111..14911
                     /locus_tag="VQT45_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2359040.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(15093..15926)
                     /locus_tag="VQT45_000685"
     CDS             complement(15093..15926)
                     /locus_tag="VQT45_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET2359041.1"
                     /translation="MNHKIAILSDIHGNATALEAVIADAKTQGASEYWLMGDIFLPGS
                     GANDLVALLKELPITASVRGNWNDCVLEALDGQYGLEDPQEIQLMRMTQFLMERMDPA
                     TTVWLRSLPLLEKKEIAGLRFSISHNLPNKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELVNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDF
                     L"
     gene            complement(15916..17763)
                     /gene="uvrC"
                     /locus_tag="VQT45_000686"
     CDS             complement(15916..17763)
                     /gene="uvrC"
                     /locus_tag="VQT45_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HET2359042.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGIHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVAAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQRKLNPQETEILLQVAEERVDYQTEGNHNKP"
     gene            complement(17803..18504)
                     /locus_tag="VQT45_000687"
     CDS             complement(17803..18504)
                     /locus_tag="VQT45_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HET2359043.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKMGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(18583..19815)
                     /gene="murN"
                     /locus_tag="VQT45_000688"
     CDS             complement(18583..19815)
                     /gene="murN"
                     /locus_tag="VQT45_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HET2359044.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(19820..21040)
                     /gene="murM"
                     /locus_tag="VQT45_000689"
     CDS             complement(19820..21040)
                     /gene="murM"
                     /locus_tag="VQT45_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HET2359045.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(21152..21931)
                     /locus_tag="VQT45_000690"
     CDS             complement(21152..21931)
                     /locus_tag="VQT45_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET2359046.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(22000..23661)
                     /locus_tag="VQT45_000691"
     CDS             complement(22000..23661)
                     /locus_tag="VQT45_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET2359047.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPEHIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKILSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(23836..26058)
                     /gene="recJ"
                     /locus_tag="VQT45_000692"
     CDS             complement(23836..26058)
                     /gene="recJ"
                     /locus_tag="VQT45_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HET2359048.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKTYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            26335..27093
                     /locus_tag="VQT45_000693"
                     /pseudo
     CDS             26335..27093
                     /locus_tag="VQT45_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            27133..27897
                     /locus_tag="VQT45_000694"
     CDS             27133..27897
                     /locus_tag="VQT45_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET2359049.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTELLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            27910..28587
                     /locus_tag="VQT45_000695"
     CDS             27910..28587
                     /locus_tag="VQT45_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2359050.1"
                     /translation="MIDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILAHIFVEFYQNTPLLVQFVIVFYGLPLISDHTIMIPIYWTAVLCMGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQTFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            28597..29256
                     /locus_tag="VQT45_000696"
     CDS             28597..29256
                     /locus_tag="VQT45_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2359051.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNTVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLCILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            29551..30741
                     /locus_tag="VQT45_000697"
     CDS             29551..30741
                     /locus_tag="VQT45_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HET2359052.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(31062..31943)
                     /locus_tag="VQT45_000698"
     CDS             complement(31062..31943)
                     /locus_tag="VQT45_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HET2359053.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(32084..33412)
                     /gene="vncS"
                     /locus_tag="VQT45_000699"
     CDS             complement(32084..33412)
                     /gene="vncS"
                     /locus_tag="VQT45_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HET2359054.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGATMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(33409..34065)
                     /gene="vncR"
                     /locus_tag="VQT45_000700"
     CDS             complement(33409..34065)
                     /gene="vncR"
                     /locus_tag="VQT45_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HET2359055.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASIAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(34114..34197)
                     /gene="pep27"
                     /locus_tag="VQT45_000701"
     CDS             complement(34114..34197)
                     /gene="pep27"
                     /locus_tag="VQT45_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198524447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HET2359056.1"
                     /translation="MRKEFHNVLSSGQLLADKRPARDYNRK"
     gene            complement(34377..35756)
                     /gene="vex3"
                     /locus_tag="VQT45_000702"
     CDS             complement(34377..35756)
                     /gene="vex3"
                     /locus_tag="VQT45_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HET2359057.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(35808..36455)
                     /gene="vex2"
                     /locus_tag="VQT45_000703"
     CDS             complement(35808..36455)
                     /gene="vex2"
                     /locus_tag="VQT45_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HET2359058.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKDTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(36468..37745)
                     /locus_tag="VQT45_000704"
     CDS             complement(36468..37745)
                     /locus_tag="VQT45_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2359059.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITSYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT        10956 a         8563 c         6933 g        11363 t
ORIGIN      
        1 aagagtataa gtccaaaact ttcgttaacc gggatacatt ataagcacat tcataccatc
       61 aaaaatagta gcaataaact tgaacaacta ccagaaacac gaaaacaggc ataattgatg
      121 aaatatcagc gctattaaac aatataaata accgctaaga ataaggctta acggttatct
      181 tctacctatc tattttttca actcctcagt cgtttatcta cctataacct aggctttacg
      241 agtgccttgc tctaccaact gagctaaatc ggcgattaca cttacagtat ggcactctga
      301 gaatagatgt caagtaatat tattcaagct ttttaatcaa aatctgacaa ggattttgcg
      361 gattccatag ttgaggaaaa atctctaact ttttaaagcc aagacctcga taaaagtcat
      421 ttgttcgatc ataatcttta ttagaacctt ctgccactgt tttgacctgc agataaccaa
      481 cttttttacg agcttcactc tctaaagtag caagcaattg gctcccaatt tttctacctt
      541 gataagcttt tttacgccga gacaatcaat ctctgcacaa tcttcactcg aataggataa
      601 gcttacaaat ctagtcaaat cactctcctg ataggcggtc caaacttgca gtgtcgtggt
      661 tccttctata taggcttgtg tgctttctgg gattccaaac cattctggca aatccttcaa
      721 aacctcagct acaactgcct ttttttgatt ttcatccttg acttcttcaa ttacaaacat
      781 cataagtttc tttcttgatt ttagtcttac tttagctttt acgaacccgc actttcgtag
      841 gaatctaagc ccttatccca aagtttaagg gaaataacaa agaaaaccag agaaatcaac
      901 atcaaacctc ctacgttaaa gaacacatcc ttttcctgta agaaatagct agctggatag
      961 taggctgtaa aggcgaaagg cacgataaag ctaatcaacc aacgaagaag agaattgtaa
     1021 atagaaatcg gatacttagc aaagtcattg aacatataga agatgtaaat catggcgcct
     1081 gactgcttag tccaaaaggc gatactggct gttgcgattt taagagaagt ataaatcaag
     1141 gtcgcaaaag gaatacaaac taggaaaagc aggaatttcg gaagagtcca aacaatgctg
     1201 gtcactgttg ttcccaataa aataccaccg actaagagtt cacccaaggc atcaatctga
     1261 aaggtttcaa ctaggatgtg aaagagagga ttgatgggac gagtcagata cttgtcaaac
     1321 tccccttttc ggactaggcg ttgccctagt gcccagagat tgtcaaaaaa gagatggtcc
     1381 attcccttgg gaatcaagga aaatccataa atgaaagcta tctcttgaaa ggtccagcct
     1441 tctaggaatg gaatatgttg aaagatgaca ttgagaaaca agagattcaa gccttgagcc
     1501 agaaagactc ccaagacacc aaccacaaaa tccaccttat attccatgat ttgtttgatg
     1561 tattgtctga taaaaatcag atgcattcgt tgatattttt tcatactaac ctccttgaat
     1621 ggtgataaag gactggaccc gtttccaaat caactgagac aatcccacca tcactaagag
     1681 ccagaagaac tgcaaaagga gtgcctgaag aatctgactg gcatcgtatt ttccaacaat
     1741 gatcataact ggagtataaa tcaaggatga aaaaggcaaa aaggagagaa tatctgaaac
     1801 aacctttgga aagaatgcca agggaatcaa actccccgac ataaaagcca ctatggaagt
     1861 cttaagtagg ttggaacccc aaagattttt aaacacaaag gctgaaaatc caaagcaaat
     1921 attaaagaaa aagttaatca gataggcgag cgttaagcta aaaagataaa tgacagttaa
     1981 tcctagcacc tctacaatac cttgacccga tatgattttc atcaagacaa tgacacttaa
     2041 aaatggaagg ccaacgctga taaaaatcaa ccacttggaa ccaagctcgg tgaaaagata
     2101 ggaggccgca aaatgcactg gtcgcaacaa acgcatgata atggagccat ccttgacctc
     2161 ctccccaatc ataaaggacg aatcggatct agtcagaaga ttggtcacaa aactcatgat
     2221 gatgtagagg gtgatatccg ccatactgaa gccctgaatc aaagactctt gcgaagaatc
     2281 aaagacagcc ttccagagat aaaaggccac aaaagccccc atgacatcgc caatccgata
     2341 gagaataaag ttgactcggt aagtaatcaa ctcctgaacc cctgcattga taaagggttt
     2401 ataacgtctc cacaatttga tcatcctaga gctcctttcg gtagaagcga cggataatat
     2461 cctcaatatc cgtatccacc atcttcaaat cgcggatttc aaaatcagac agggtttgct
     2521 tgataatgtc agctgactgg tagcgagaac tatcaaattc aatgttgagg ctgtttcctt
     2581 gtctatcaat ggtcatatca gacagaccgt catagtgaga gacgagatga ctttgacctg
     2641 gtagcagttc aaaagagaga gtcttcatct taccaaaggt ctccttgagt tggctcaccg
     2701 ttccatcaaa aatctcttgc cccttgtcaa tcatgaaaat ccgatcacaa agttgctcaa
     2761 tatcactcaa atcgtgagtg gtcaaaagaa tggtagtttc ttcctcttga ttgatctgag
     2821 taattgcccg acgaatatta tccttaaccg aaacgtccaa accaatggtc ggctcatcta
     2881 aaaaaagaac cttgggattg tggagcaagg aggccgcaat atccgcccgc atccgttgtc
     2941 ccagtgaaag agtccgcacg ggatccttga taaagtcctt caaatccaag acttcattca
     3001 aaaagtccat acgcttatga aagagcgagt ctggcacatc ataaatctct tttaagacag
     3061 tgtaggtctc ttgcagagcc aaatcccacc atagctgggt gcgttgtcca aagactacgc
     3121 caatatcttt gacataatct tgccgattgt cctggggaat cttgccgtta atccgacaaa
     3181 aaccagatgt tggtttcaaa attcctgtca gcattttaat ggttgtcgac ttcccagcac
     3241 catttgcccc gataaatcct aaaatctgcc cttttggaac ctcaaaggtc aaatccttga
     3301 ccgcttcaaa ggtctgcttt tcaggatgaa taaaggagcg caaagccccc ttcaagcccg
     3361 gttccttaac agtcttcaca aaatttttct gaagatgttc cacttctatc attgccatat
     3421 ctatctccct atcgtaagga atagcaacat tgtgttttta actacaaata ttctaaatcc
     3481 ttgctttcta caccttctac attttattac tacaaaaggc tttataccaa cctattatag
     3541 tccaataaaa aacgaaatgc aagagtttgc ctatggattg tgaaattagg atttctctca
     3601 taaaataata cttttaatca aaaattctgt ttaatagttt aaattaccaa cctactcatc
     3661 ttctcaccag agggcggtat taactttgat cataaaatcg gatactccct ctatccagaa
     3721 aatatgctca gaatgattgt ctctaaacaa tacctgctct tttacctcat tcatgaaaaa
     3781 gaagtccata ccctgagaat tatcaactca cgcatcgact acctaaacca actcgaccac
     3841 ctctttcgta catgtaggaa actattttcc tcacaaataa tctcattata aaatccaata
     3901 aattttttta gctcacttga atattttctt tgtatcgttt tatcagcttc aatctgatct
     3961 agacttgtta ccttggaacg acttgaaata acctttataa aataacactt aaggctttca
     4021 tcatctcgta taaatttttc aatagtgata taaaaagctt tcatattctg tttgtaatca
     4081 gatatcaatt gattaatttt atcattctga tgaagattcg ataccataat atatagcgga
     4141 ttgaaataag atgagaacaa atcgattggg aaagtaaaat taatttctat aaatgtttta
     4201 gcaattgttt cgtactattt tagattcagt ctactataca taaactaacc tcctcattat
     4261 tagcaaggat tctactgatt ataacctaat tcttagacta cttcaagact aactgtccaa
     4321 taataatcta cagataaatc atccactctt aataaaattt tattcaatcc atctactcat
     4381 tcccaaaagg ttgctgtata atgcaagaca tttttcttac tgattttact tttccttacc
     4441 ctcaatttag tgagctaata aattattctt cttcaaaagg ttgagattta tctagtaact
     4501 ctaaaacatt aatggtaggt agcaacattg cttcactgct atcaattgcc gaaactattg
     4561 aaacaataga acgtaaataa tgataaagaa tagcagtacc atttacgtat agaatatcgg
     4621 tgatattttc atctatattt atttcaaaat atcctattac agttacagat atttttttca
     4681 tggcatcttt gtcaactaaa gaaacactaa gttttacggc tccatgacta taatcatctg
     4741 tatgaccaac cttaactatg ggatataata tatcgaaggt aaatgtgaac aaactgatta
     4801 ggaaatttaa accaacttct aacaatctgt tatactaaat gaaaaccaaa gagcaaacta
     4861 ggaaactagc ctcaggttgc tcaaaacact gttttgaggt tgtggataga actgacgaag
     4921 tcagtaacca tacgcacggc aaggcgacgt tgacgtggtt tgaagagatt ttcgaagagt
     4981 attagaaagc tcgatggact attccagatt cattccacta gatttcgaaa tcgagtaggg
     5041 gataatctct agcccctctc acaccaccgt acgtgccgtt cggcatacgg cggttcaact
     5101 aactgttaac gcatgtcgtt caaggtaata atccaaacac gaaaccagtc cacgtttttc
     5161 aaggactggt tttgatatag cacgtttaag taccgacttc tgagctacta tagtagattg
     5221 aaactagaat agtacatctc ttcttctaaa acattgttag aaatcgattt ggctgccctg
     5281 atcgattcgt cctactctta tttcatttta ctataattga tagtggtcgc cccagccaga
     5341 taccttatcc gctatatagg ccttattatc atgttcctgt tcgtagagcc acgatttcgc
     5401 tatcccttcc tctgacgatt cttatttcct gcgtcagact tgggaatcgc tattgggttc
     5461 accggtagca ggtgcccacc gaggacttac acctcagata tacgacatgc ccgtcgtaca
     5521 tcaaaaaaag ttgagacata gcgtcttcaa cttttttaca ttactttaac tactgattaa
     5581 agtgagttta cgtcaacttt gataccaaca ccttgagtag ttgtgatagt caagtttgtt
     5641 acgtaagttc ctttagctgt agctggtttt gctttttgga ttgtttcgtt gaaagcttta
     5701 aagttttcaa ccaatttttc agcttcaaat gatactttac cgatgattgc ttgaacgtta
     5761 cctgcacggt cagcacggta agtgatttta ccacctttag actcttcaac tgctttagca
     5821 acatccattg ttacagtacc agttttaggg tttggcatca agttacgtgg tccaaggaca
     5881 cgtccaagac gtccaacaag acccatcata tcaggtgtag cgataactac gtcgaagtcc
     5941 aaccaaccgt cgttgatttt agcaacaagg tcatcttcac caacaaagtc tgcaccagca
     6001 gcttttgctt cttcagcttt tgcaccacgt gcgaaaacaa gaacgcgtga agttttacca
     6061 gtaccgtttg gcaataccat tgctccacgg atttgttgat cagctttttt aacgtcgatg
     6121 ttcaagttgt aagcaacttc tacagttgcg tcaaattttg caaagtttgt ttcttttgca
     6181 agtgctacag cttcttctac gctgtatgct tttgtgctgt cgattttctc aagagcagca
     6241 cgaagttgtt tgcttttttt agccattttc tattctcctt gtaagtggtt caatcgattt
     6301 tcatctccca cgtcacttct cgaaatgatg aagtcttgcg ggttttcagt ctattagatt
     6361 cttttcctac ggccttaagc tcccttgctg tacccaagta caagcatcag tcacttgcct
     6421 agtatgaaaa gcaactaata gactgctgtg agattttcta ctgtgttatt gattagtcaa
     6481 taacagtgaa tcccatagaa cgagcagtac cttcgatcat acgcactgca gactctacgt
     6541 ttgctgcgtt caaatctggc atcttagttt ctgcaatttc ttgtacttgt gcacgagtaa
     6601 ctgtagcaac tttagtttta ttaggtgtac ctgatccttt ttcaacacct gcagcttttt
     6661 tcaaaagaac agcagctggt ggtgttttcg taacgaaagt aaatgattta tcttcgtaaa
     6721 ctgagataac aactggaatg atcataccag cttggtcagc tgtacgagcg ttgaactctt
     6781 ttgtgaatcc catgatgttg ataccagctt gaccaagagc aggtccaacc ggtggagctg
     6841 gtgtagcttt accagcaggg atttgcaatt ttacaagttt ttcgactttt ttagccattt
     6901 ttaaatcctc ctttgtggtt ttggcggtaa ttagagattt ttacctccca caagtatgtt
     6961 tttcacatac ccatctatta tacactattt atctggaatt gcaagagaaa agtttatttt
     7021 ttaatcgacg taatctccac cttcaaagcc gaaatactct tccaaactga ggccactagc
     7081 tgcaatctct ttagcctctt ttccgacata acgaaggtgc cattcctcag ccatatagcc
     7141 tgtttccttt tccttacctt tgagataacg tacaacaaag ccataatcag ccgcatgatc
     7201 caagagccat tgggccgctt tttcttctgt caccaaatca ccatttgtcc caatcacatc
     7261 aaaggctaaa cctgtctggt gctcgctata gccaggacgg gcagaataac ggtcggcagc
     7321 ttctttccca tcttgattga cataatcttg atagagcttg gtctgagttt cataacttct
     7381 aaagccactg taatgatcgc taatggggaa acctgcctct tgcatagctt tgatgagctt
     7441 gaccaactca gccttggctg ttggattttc ccctggattg tagtcttttg acaatggata
     7501 gtgtttgttg gctacgatga tttcatcgta tttcccttga atgctgtaat agtctccttt
     7561 gttaaccact tctgcttttt tctgggcagc tccttgagac ttacttccta ctgttccatc
     7621 agctttagca gtttgctctg tcttagctgc tccatcttca ttttttgctt tttcttgtga
     7681 acaagctgct agactcaagg ctagcaaggc tgtcaagaca aggtatcttt ttttcatctt
     7741 tactccttta tttctaatag tttatctact tctgatgata aacgttcgac taatctttta
     7801 atctcatcag gttttgattg gcagatttct gctgtcattt cttcaaaggg aatccaccat
     7861 actggaccac gtccattgag gccataacca ttcatatcac ctcttcgtct aggaaacaga
     7921 tgccaatgga gatgagcatc gccatttcct agtagttcga tattcatttt ctcagcagca
     7981 aaggccttgg caactgcctc ttggaccaca ctcatttctt ctagaaaacg tattctagtt
     8041 ttcttttcta aatgatgcaa ttcgctgaca tgttccttgg ctagaaagag actatagcct
     8101 gcaaaatact ggtggtctcc aatcacaaga tagcctgttt ccaactcttt gacaaaatag
     8161 ggattttctc ccttcttgat gagctcaatt ctctggcaaa tcaaacacat attagtctac
     8221 caatgcactc ttaagatagg catcgaccat tcgttctgtt gcgaccaccg agtcaatatg
     8281 agtgcgctca taagaatgac tagactcgat acccgcacca agaagggcat gcttgacctc
     8341 tgcccctgca gacatagccg ctgaagcatc cgaaccataa aatggataga tgtccagctt
     8401 aaaaggaata tcttgctctt tagccaaggc aaccaagtgt tgacggaagt catagtgata
     8461 aggacctgag gcatccttga cacagataga tactgtgtac tcatttgtct gctggtcatc
     8521 tcccatagct cccatatcca cagccagata ttctactacc tgagcaggaa tgttagaatt
     8581 agcaccatgt cctacttctt caaaaactga aaaagcaaaa tgagttgtta ctggcaattc
     8641 aatcttctct ttcttataaa tacgaagcag gttgagcaac atcgctgcgc tgaccttatc
     8701 atccaaatga cgagacttga taaaacctgt atcagtcaca acagttcgtg gatcgaagct
     8761 gataaaatca ccgacctcaa tcccaagagc acgagtttct ttttcattgc ttacttttac
     8821 atccaaacgc acttccatat tgtcctgcgt gcgttctgca gttcctgcat ccttgtagac
     8881 atggcaagaa gtttggtgga tgaggatggt tcctaatacc ttttgacctg tgctagccac
     8941 atgaacggta cagttttcac cttcaatcat gttccaagga aaaccaccga tacggtccaa
     9001 tttaagacga ccatctggtt tgacagcacg aacaatagca cccagtgtgt ccacatgggc
     9061 agtcacatag cgatgttgct catcattttg acctttgatg gtcacattga caccaccctt
     9121 ggctgtgcga actggctggt aaccaaaacc ttctagagtc ttgactaaat aattcgaaat
     9181 ttcacgagtg aagcccgttg gcgatgcgat ggctgtcagt tctttgatat attctactgt
     9241 ttgattcatt tcttcacctc tttcgctacc tattataaca catttatcat cggataaaaa
     9301 aagaaaatca ctcctgtaga cttggctaca aaagtgattt aagtgattat tccatttcaa
     9361 aaacatcgct ttcttgcttg tttggtagaa ccaatgagag caagattcca acaatggctg
     9421 gcaccaacca tgggagagat gccttggcaa aaggaagaac gctaacaaga tttgcaagaa
     9481 actcaacctt aaacgagctt cctagtacgc ttgcaatggc aataactgta accacagcaa
     9541 ttgtcaactg catacctggt tttgaaaggg caacaaattt gttgacaatg acaatcataa
     9601 cgatagcaat cgtgattggg tacaagataa ccagtactgg aattgagtac ttgataatcg
     9661 catcaagacc caaattggca atagcaaatc caatcaaggt aaaggctgtc gcataaacct
     9721 tgtagctgat ttgtgggaag cgctcattaa agaactcagc tgttgacaca atcaaaccaa
     9781 cagtcgttgt gaagcaggtt acggtaacca tagctgcaag gaagagttga gctgttgagc
     9841 caaagatttc ttgagtggct tgtgacaaga tgtaaacacc tggtgttcca cccttcatcg
     9901 cttcagctgg tactgggaaa tgatttccaa gaaaacctaa accgatgtaa agagcgctga
     9961 aggcaagggc aacaacgata ccaacaaccc aaatagttga aatgtattct ttcttacttg
    10021 aaaatccaag ttgtttcaag gtttgaactg cgattacgct aaaggccact gaggcaaggg
    10081 cgtccaaggt attataacct tctaggaaac ctgtaccaaa ggcagaagct tgataagcag
    10141 ctgaagcagc ttgaggactt gttccaccat atttgatagc tcccagaacg accaagataa
    10201 caatcaaaat tgcaaagact ggcgttaaaa tacgtccaat gcggtctaag atttttgatg
    10261 gattaagcga aatcaaatag gctgccgcaa aatacagaac cgtaaataca atcaagccaa
    10321 gtcctttatt tgcatccgac aaaagggggc taatccctac ttcgtaagct gttgtagcag
    10381 tacgtggggt agcaaagaat ggaccgattg acaagtaaag aactgagagg taaagagtcg
    10441 caaaccaagg cgctatcttc gttgaaatct cgtagatata tcctttagga tttagcgttc
    10501 caataataag ggtcaagacg gcgataccaa cgcctgaaaa gacaaaacct gcgatggcag
    10561 gaagaaaatg ttctccagat agagcaccta gagaaggcgg aaaaatcaag ttccccgcac
    10621 caaaaaatat tccaaacagg agcaaacctg ttagggtacc ttttttagcc ataaaaatct
    10681 ccttcatatt tataaaatac tgatctagta taccacgatt aggagtctga aaaaagcatc
    10741 acgaggcaaa tattaaatgt tttcaatttt cttaaaaata agaattatct aaaaataaaa
    10801 ctctcctacc cagtccacac caagtaggag aaatgcaaaa ttttaaagtt cttcaaaggc
    10861 taacatgcca ccctggacat tgataacatt ataaccttgt tctaatagga attggcaagc
    10921 acgcgccgat ctcattccag atttgcaaat aatataatgc aagcgatctt tgtccaatta
    10981 atcataacta tcagccaatt gactaagcgg taggttgtgg gcaccttcta aatgaagagc
    11041 tgcaaactca tccacttctc tcacatccac tagagaaagc tggtcgtttt ggtaaagctg
    11101 gtaaaatgcg tcaaaggcta tttctttcat tctttttctt ctaatactct tcgaaaatct
    11161 cttcaaacca cgtcagcgtc gccttaccgt gcgtatgtta ccgacttcgt cagttttatc
    11221 tgcaacttca aagctgtact ttgagcagcc tacgactagc ttcctagttt gctctttgat
    11281 tttcattgac tataaaatgg ttttaattct ttttttcaaa tctggcacta cttctgcctc
    11341 aaaccaagga tttttggcca tccagatttg atttcgtggt gatgggtgaa ctagcggaaa
    11401 ataggctggc agatagtctt tatagtgttt caccctctcc gttaccttcc cactgatttt
    11461 ctcctgtaaa tagtaggctt gggcatattg cccaatcaag agggttaact gaatatcagg
    11521 caattcctgt aagagctgcg gatgccattt ttctgcaaaa cctgtacaag gcggaagatc
    11581 acccgacttg ccatgtcctg gaaagtagaa atccataggc aaaacagcaa aataacctga
    11641 attgtaaaag gtatcttcat ccacacctag ccagtcccgc aaacggtcac cacttttatc
    11701 tttccagtaa aggcctgctt cttgagtttt aagtcccgga gcctgaccga tgatattgat
    11761 gcgagcagtt tttggcgctg caaagagagg ctcaatgcca cgctctgtat agctggcatt
    11821 ctgcgaatcc gccatgatag cctgtttgat tctttcgatt tgagacatct actttccctc
    11881 caaaaagaag tccaagcata agatctcaga cttctatcgt tttatttgat caattcgtaa
    11941 atagcttcgg cataaattgc tgctgctcgg aagagatcgt ccaaggcaat aaattcattg
    12001 gcttggtgca tggtatcaat tgagtctggg aacatagcac cataggcaac tccgcgctct
    12061 aacaagcgac caaaggttcc accaccgatg acttgttcat gacctttaag gcctgtttgt
    12121 ttttcataga cattcaacaa ggtttgcaca agtggatctt ccattggcac atagtgaggg
    12181 gtatgaccat gttctgatag actgacagaa gcaactggca agttttctag gattgacttg
    12241 atttgttctg gacttgttcc ttttggatag cggatgttaa gggcaatggt attatcagca
    12301 cttgtttcat cgaagcggaa gacgccggca ttcatagaaa gagcacccat cttttcatcc
    12361 acatgagcaa tcttgagatt ttcaccctca tgatcgttca agagaatttt acctgcgatg
    12421 tcaaggtagt ctttggctgg accagcaaag ccaaactggc tgaggaagag ggcaaggtaa
    12481 gttgcgccat tgacacctga agcaggcata gcaccgtggg ctgatttacc aatgatcgtc
    12541 accttgtatt ggccagcttc ttcttggagt tctcctctaa gtttgtgttc tgcaacaaag
    12601 gcatctagtt tagcttgcaa gtctgtcaag tcacctgaaa cgactgctgt tgctgattct
    12661 ggtaccatat tttcacgtaa accacctgta aagctgtgaa gacgggctgc acctgtattt
    12721 tcacctgcaa agtggaggta ttccgtgatg tttccttttt caccattgat gattggaaat
    12781 tcagcatctg gtgagaaacc aaagtctggc ttggcgagtc ctacgtgctc gaagtagtag
    12841 tccatatctg cccagcctga ttcttcgtct gttccaacga tgaagcgaac tttcttagaa
    12901 gttggaaggc ccaattcttt gatgattttc aaaccatagt agcaagctgt tgtaggtccc
    12961 ttgtcatctg aagcaccacg cgcataaagg cgaccatctt tgatagttgg tgtgtaaggg
    13021 tctgtgtccc aaccgctacc agctggaacc acgtccatat gggcaaagat tccgagaact
    13081 tcttctccat caccaaactc aaaatgtcct gcatagttat caacattttt agttggataa
    13141 ccatcacggt ctgcgatttc aaggaatttt tccaaggctt ttactggacc aggtccaaat
    13201 ggatgttggg catcagcctt gctatcatca cgttctgagt tgatttccaa aaggctaaac
    13261 aagtcagcca agaggtcttc tttgcgtttt tctacttctg ctgtaaaatc aattgctatc
    13321 attttttctt cttcctatct tttttcgatg atttcatcta ctggcaagcg gtagcttggt
    13381 tccaatttgt cgtctgtgta acccactgtg atcaagagtt ctgggcggaa acggtcttca
    13441 atttccaaaa cctcattgac ttttgatttg tcaaaaccaa ggataatatt ggaaccaatt
    13501 ccttggtctg taagagcgag aaccaagttc atagcaacca aacctgcatt gagtgctagg
    13561 tagtcgctga cttgttgttc attgtagcgt gcaaattcag ctggcaaatt tttcatgaag
    13621 tattgaagtt gttcttctga gaaattgtta gcaccaccaa ctcgggcaat cttacgagcg
    13681 cgtttggcaa ggtctgtatc tgtaaatagg gcaatggtta caggtgctga tgatacctgc
    13741 tcaaagtttg aaccataagc caactttgcc agttcagcat ttttctcacg aacaactaca
    13801 aatttccaag gctggctgtt gtgggcgctt ggcgccaagg ttgcaatttc gatagccgta
    13861 cgcacatctt ttagatcaac aggcttatca gtgaaatgct tggtcgcatg acgtttttta
    13921 tttaattcaa gaaatttcat aatcgatttc cttttctaat tctactgctt ccattctacc
    13981 ataatttgaa agagcttgca gggatttttc atgattaagt ttttctatca cagacataaa
    14041 agatatatat tggtttatca ggaaagtttc tgataaacta gcaagtactt tacatttgaa
    14101 tggagacagt atgaaaaaat ttagcctatt actagctatc ctaccatttt tggttgcctg
    14161 tgggaatcaa gctacaccca aagagactag cgctcaaaag acaatcgtcc ttgctacagc
    14221 tggcgacgtg ccaccatttg actacgaaga taaaggcaat ctgacaggct tcgatatcga
    14281 agttctaaag gcagtagatg aaaaactcag cgactacgag attcaatttc aaagaaccgc
    14341 ctgggaaagt atcttcccag gacttgattc tggtcactat caggctgcgg ccaataattt
    14401 gagttacaca aaagagcgtg ctgaaaaata cctttactcg cttccgattt ccaacaatcc
    14461 cctcgtcctt gtcagcaaca agaaaaatcc tttgacttct cttgaccaga tcgctggtaa
    14521 aacaacacaa gaggataccg gaacttctaa cgctcaattc atcaataact ggaatcagaa
    14581 acacactgat aatcccgcta caattaattt ttctggtgag gatattggta aacgaatcct
    14641 agaccttgct aacggagagt ttgatttcct agtttttgac aaggtatccg ttcaaaagat
    14701 tatcaaggac cgtggtttag acctctcagt cgttgattta ccttctgcag atagccccag
    14761 caattatatc attttctcaa gcgaccaaaa agagtttaaa gagcaatttg ataaagcact
    14821 caaagaactc tatcaagacg gaacccttga aaaactcagc aatacctatc taggtggttc
    14881 ttacctccca gatcaatctc agttacaata acactcttcg aaaatctctt caaaccacgt
    14941 cagctttatc tgcaacctca aagctgtgct ttgagcaacc tacggctagc ttcctagttt
    15001 gctctttgat tttcattgag tataagatat actaaaagcg attggaccag ccaatcgctt
    15061 ttttagtttg cattggctat tttaggaaac tcttacaaaa aatcaaaaaa attcttcaca
    15121 tcctctacat acccatgctt ttctattaag ctggctaaaa gttccagatt gtgcccctga
    15181 tagttatcgt cacgacgcag ttcttcatac atttcaataa agggaagccc cttggacttg
    15241 gccaattcta actcagcctc gtaatcataa gcaactttac gaaattggat attgaccaat
    15301 tccccatctt caacttctat cacggcatac tgggcacggt gattttttaa cgcctcccaa
    15361 ttaaaatagg gcatgccaat cgaccctgga ttgatgattt gttgcccttg acttccataa
    15421 cgaagcaact gcttgtgaac atgaccataa actgccacgt ccgtttccgc atctagcagt
    15481 tggtcaaatt tctctgtatc attctcaact agcaagtcac caccatagtt cttatttggc
    15541 aaattatgag agatagaaaa gcgcagtcca gcaatttctt tcttttccag caaaggcaag
    15601 cttcgtagcc agacagtcgt tgcaggatcc attcgctcca tcaaaaactg agtcattcgc
    15661 atgagctgga tttcctgtgg gtcttctaag ccatattgcc catctaaagc ctcaaggaca
    15721 caatcattcc aattgcctcg aacacttgcc gtgataggaa gttcctttaa cagagcgacc
    15781 aagtcatttg cacctgaacc agggaggaaa atgtctccca tgagccaata ttcactggct
    15841 ccttgagttt tagcatctgc aatcactgct tctagcgccg tcgcattgcc atgaatatct
    15901 gataaaattg cgattttatg gtttattgtg gtttccttcc gtttggtaat ctactctttc
    15961 ttccgccact tgaagcaaga tttctgtttc ctgcgggttc aactttcttt gcacagcctc
    16021 tgctactgct cttggtactc caacttcgac aatctcatcc acactggctt ccttgatttt
    16081 ggtcagagac ttgaagtgcc tcatgagatt ttgcttgcgt ttaggtccca gaccatcaat
    16141 cccatccaat tgagatgaga aagaattttt ggagcgcagt tggcggtgga aggtaatggc
    16201 aaagcggtgg acctcatctt gaatgcgttg gaggaggaaa aattcctgag aattgcgaga
    16261 caagtccacc acttccagcg gatctccaaa gagcaattca tgggtttggt gcttatcatt
    16321 cttttgcaga cctgcaattg gaatatccaa gcccagttct tcttggatga cttgcttagc
    16381 aatattgact tgaccttgcc ccccatcaat cacaatcaaa tctggaggag tcaaagcctc
    16441 acgctgtact cgaccatagc gtcttcgaat gacttctctc atactagcat agtcgtccgg
    16501 cccaacaacg gtttttatct tgtacttacg gtaatctttt ttacttggcc tgccgttaac
    16561 aaagaccacc atggctgaaa caggactggt ccccatgatg ttggagttat cgaaggactc
    16621 gatgcgaact ggagtcggaa tttggagcaa acgtcctaga ttttcaatag ctccttgggt
    16681 cttttcgact gatttttcta gcaggttaaa tttctgctcc agactaacac gtgcattttt
    16741 tatggctaga ttgaccagct gttttttctc tccacgttgg ggtttgagaa tcttggtatc
    16801 caccaaagcc ttgacagctt cttcgtcaat atcctgcgga atcagtacct cattgggaac
    16861 taggtgagat ttttcttgat agaattgtcc cacataggtc aagaaatcct catctggatc
    16921 attgaagtag gggaagagat tgacatcgcg ctcgatgagc ttgccctgac gaacaaagaa
    16981 aacctgcaca cacatccagc ccttatccac atagtagcca aagacatcgc gattttggag
    17041 atccttagcc atgacccgtt gcttggttcg aagcgttcca atagcctgaa tcaggtcacg
    17101 gtattccgcc gcacgttcaa actccatact ttgtgctgct actgccattt tactcttgag
    17161 atcatcgatg attttgtcat cctgaccttt cagaaaatca gacacctcct gagccataga
    17221 cttgaaataa gcctcatcct tcttacagat ggtgtgggcc atacactggc cgatatggta
    17281 ataaaaacag accttagagg gcgggttggt acattttcga aaagggaaaa tcctatctag
    17341 aagtcgcttg atttcattgg ctgcccccac atctggataa gggccaaaat aaagaccacc
    17401 gtcctttttg acctgacgag taatgataag ccgtggatag cgctcattgg tgattttgat
    17461 gaaaggatag gacttgtcat ccttgagcat gatattgtac ttgggcttat tttccttgat
    17521 caagttgatt tccagcagaa gcgcctcaat attggactca gtgacgataa attcaaaatc
    17581 cacaatttca gacaccagag cctctgtctt ggtatcatga attccacgaa aataggaccg
    17641 tactcgatta cgcagatttt tagcctttcc tacatagata atggtgccat ttttatcctt
    17701 atgaatgtag caaccagggc tggtcggcaa gagctctagt tttgatttaa tcaagttgtt
    17761 catagttcca ttatagcaaa aaaagtaggg aaagatagta ccctactcac tagtctcata
    17821 tatttttcgg aggtttgcaa catcctcttc ctggatacca taaaaggaac ctgctggttg
    17881 catgacagac ttctcatctg tatggtccaa gccaatcgca tgacctaact catgttctgc
    17941 cgtatggaca aggcgttcat aggagtagcc atagtatgga ttggacaaat aataatgatt
    18001 caaccgcacc gttacggaca agaattgccc tgttaagaga ttagtttgac tttccgcctc
    18061 tcctgccaca ggagtgcctc cgtcgttcat ctccgtagcc gtaatatccg ccttactaga
    18121 ctcagtcacg agttcaaagt taaaagcacc agtttgattc cagttctgga ttgcttctaa
    18181 ataagcctct tgaaagcgtg aatccatctg cggatccagg taaatacgag cagaggcctg
    18241 tgcccacctt ccttcagaat gctggtgact atctgtctgg cttaacttag gcagttgccc
    18301 tgttttctcc cattggtcaa tactttgttg acccattttt actgaccgtt ctgcttgctt
    18361 tagcgctcct tgaaaatccc cgttcagata ccagagaagt ccgaaagcaa gcacacataa
    18421 gagcacaact atccaaacca gacgccaaaa caaacgccac acaaaagaaa agaaagcccc
    18481 tatcaaacga aaaagccagc gcatgtctct ccacctttct agcaaataag aattatttta
    18541 ctaaaagaag ctaaaagaaa tctaaatact gactttttca tcttaacgtc ctactatttt
    18601 tttgagtaac tggatagctt tgtattttaa aggcgatgga tggtaacgga aagtacctgc
    18661 tttgcgtaca atatagccat taaaattctg tttaaaacgc aaaacaccat cacttccatc
    18721 aaaaatccct tgaatgccta ggaagttgta tttaggtatt ccacgtttta tgctttccaa
    18781 cataacatat ttttgaagca gtgcaggggc atagaactta ttaaactcag tgtaggaacc
    18841 actaaagaga taagtcgttt cctgaggcat ataaacaaat aaactcccag ctaaaacaat
    18901 atcttcttct ccatattttt caatcaagtc tcgcgcttct gcttttcgaa cttcaaacgt
    18961 ttcaaattga ctagaatatt ctctcagttg attttgtttt ttctcagaat gaggattttt
    19021 actcaaatca agtcgcaact tgtccaagtt ttcttctagt ttactttgtt caccttgcaa
    19081 tttgctcata tactccgaaa aattcaagct tgctatgaga aactccgctt gttctccaaa
    19141 agtatcataa aaatgctcat aatattctaa acttttatca ctatattctc tacgttcaga
    19201 ggtttctttt gttatattct taaaaatcga tagttcttca cgttttaact ttttcaaccg
    19261 aatgccaaag gtttcagcct ttttcaccaa gggtttaccc tttttgctaa aacttttaag
    19321 caaactcttt tcagttaatt cagttaaatc tttatagtat aaccaatctg gttctccacc
    19381 tgggtaacct gttgttaagc catcaaattg ataacctaaa tcagtcaaac cttgaataat
    19441 actttttttc tcagcatcta ttggattacc ttggctatca aaagtttgat aagtttcata
    19501 aggttttaca agcaactcta atacaccatt ttgcttggca tattctttta actctgcata
    19561 aaaaactgga agagcatctt gttgggtata aatcggcccc gaattgagtt ccatatgcag
    19621 accacccagc atgggcaagc tataaaccag agctgcaact tgaatttctc cttcttgttt
    19681 caaagcaaga taaacaattc gagcccctct tttttctagc aaatccccca tctggacaga
    19741 ttgcataaag gaacgagaag aaacctgatc agaataagtc tgaaactctt ctttcgtgag
    19801 tgttgttagt gccatatact tactttctat gtttttttct taatgtttta cggaaatcaa
    19861 gagcaagtct taacagagga tagagaggat gagtgggcat tgtaaattca cccaagtatt
    19921 cttcaatcgt tggattaaat ttttccttaa aatgataaag tccaccattg agagagtttt
    19981 caacaccacc taaattttgc cagaccatac ctcgctcaaa ggcatagcga gccgtttcat
    20041 accatgttaa aattggtgca ttgtaacgtt taaaatcatc atccatacca gcatatatat
    20101 tgacagaggt agtaccaaat tccaaactca aagtagccgc taaaggaact ctcgcttgac
    20161 ctacatctat atattcctgc aagaaggtca attcctctaa caaacgttct ttttccttct
    20221 tctgcgcttc tacttttgaa gttcgagtcg actcagtaaa ggtctcttcc aaggctctat
    20281 ttttcgctaa ctgttcttct aactcttgcg aacgtttaga aacatccaag gtggccaagg
    20341 tgatataggc cttgtcctta aaattatcta acaatttttt ataataggct tcattcctca
    20401 aatgaatctc ttttcgcttc tcagtttttt tcatcaactc cgaaaatgaa tctaatagtt
    20461 ccagtccacc atattgaatc tcaagccctt tgtttcgtgc tgttcgaata gcctgttttg
    20521 ttgacttgga aagtttatct tcttcaaaat tttccttgta tattttcgcc tgaatacgag
    20581 gttgaatggt gtctcccatt tcctccgttt ttcctgacca ccttactccc atttgttgca
    20641 aactatcaat aatagccaga ttttcaggaa attctgtctt ttcctgattg attaaacttt
    20701 gagataggca aatacttggg tcaaaagtca caaaaaccgc tctcttactg cgagcatagg
    20761 acttaataga ctgaatggca aaattcaaga gttctttatc cccataatcc aatataggtc
    20821 ctcttgggat gtaaaacatt ttatagccta gcggaagagt tctaatcaaa atactagctg
    20881 tcgccagtaa tttttcttcc ctgtaaacac caaacttctc atgttgccaa ttagacttaa
    20941 cttcctccca agcactactt tgtaatacat tggctaattc atgttctttg acaaactgat
    21001 catattctaa tgtgggaatg ccaatttgat aacggtacat ttcctactct ctttcctcca
    21061 gtattttatt actattctac tactttcgtt tgaaaagtct agtgaaaaca tattttattt
    21121 tagttctact ccccctatgc tgaagttcaa actaagtcag tctctcttct aatttgaaat
    21181 caattggtag ggttgttaaa aaaacttcca attgtttttc ccagtagtac cactcgtgag
    21241 ttccagcgct atggctatag gtcacatcaa aacctagttt tttgagattt ttcactgcga
    21301 gattattggc ttcgtacaag aaatcctgtt cgccacacca cgcccaaagt ttggtctttt
    21361 tatccgattt tttagccaga ctttcaagag aatagggact agttgtccag tctctaatct
    21421 ctccaaaaac acctctccag taggctggac ttcccagatt ttgactttca ggagaaaagt
    21481 tttgaaagct gagggcacct gaaaaactag ctgcatgaga aaaacgattt gtcgcaagag
    21541 ccagtttgaa gcagccgtaa cctcccatag aaagaccagc gataaaggtc ttttcacgct
    21601 tgctagtcat attagggaag aagcgtttca gaacctgtgg caattcctct gctagagccg
    21661 tgtagtagtc aaaaccatac tgggtatcgg tgtaccaacc attgctggta ttgggcataa
    21721 caacgatgag attagttcct cgaagcaagc gttctacatt ggtccgctta agccaactat
    21781 tatgatttcc agacatcccg tgcaaaaggt acaagacggg aatatcttca cactctggtt
    21841 cttccactcg attggcatca gggtagagga cattcacccc ccactccata tccaatactt
    21901 gtgagtaata ctcgattttc attactgcca tgattttctc cttctatttt tctataagaa
    21961 aaagccgaaa ctcgactttc tctctgttta tttcaacgat tattttgctt ccatgactac
    22021 tggtaaaata gctggacgac gcttggtttg gtcaaagaga tacttggtca aattatctcg
    22081 aaccttccct ttaagatctg cccagtcaaa gtcatctcct tgaagataat cttctaccgt
    22141 ttggttaatc aattctgaac tttcacggag aatatcgcga ctcttcttga gataaacaaa
    22201 tccgcgcgta tgaacacgag ccctagccac aattttcttc tcacgacggt tgactgtaat
    22261 agccacgatg aaaattccat cctctgacaa gatcttacgg tcacgaagaa caacatttcc
    22321 aacatcacca atggcattcc catcaatcaa gatatctcct gctgaaaccg atccagctgg
    22381 aacaaagtct ccattctcgt aagccatggt cgtccccttt ttaggaatga agatgtgttc
    22441 tggcaacatc ccaactgcca tggcagcctt agcgtgagca tccaactcac gatactcccc
    22501 ttggacaggg aagaggtact taggttgcaa aagattgatc atcagctgca aatcacgcac
    22561 atttccgtgc cctgatacat gtaaactttg ggtaatcaat ttgacaaccc cacctgcctg
    22621 ataaatcata ttttccacac gcgcaacaaa ggcttcttta gcaatagacg gagccgtagc
    22681 aatatagacc aggtccccat ccttgatttc tacataacga tggcgaccaa tcgacatctt
    22741 acgaagtcca ttgataggtt cacccatacg acctgtctca agaataatca actcatggtc
    22801 ttcaaagcga gacatatctt taggcttaat caagagaatt tcgttggcta aagacaactt
    22861 cttaagacga atcgctgtgc ggacgatatt ttcaatatca aatcctgtca agacgatacg
    22921 tcgacctgtt ttatccgcag cgtcaaaaat ctgctgaata cgagaaagat tactggaaac
    22981 agctgcaacg atgatacgac cttcccagtc agcaatagtt tgggtaattt catccctaac
    23041 ttcactttca ctagccacct gaatattgct gtctgcattg gccgaatcac tgaggagagc
    23101 caggacgccg tcacgaccaa tctctgccaa acgagcaaaa tcagttgcat aagattcact
    23161 agccgtttgg tcaaatttga agtcacctgt ataaacgatg cttccttccg atgtcttcaa
    23221 gacaattccc agactctctg gaacggagta agtcgtaggg aagaaggaaa ccactgtccc
    23281 accaaaatca atctccgtat tctcatcaat gacatggaaa tcattaaatt tcttaacggc
    23341 atcatttcct ttgacaaaga gctttgccaa ctcaatggtc aactcagacc caaatacagg
    23401 aactttagcc tctgccaaga gataaggtag agcaccaatg gcatccgcat gcccgtgggt
    23461 caagaaaacc ccagcaatac ggtcgctatt ttcaaaaagg taatccatgt ttggaatcac
    23521 cacatcgacc cctaattgtt cattttcagg atattttaac cctacattca aaacaaaaat
    23581 ggactctcca atttcagcaa tgtacatatt ttttccattc tcacgcacac caccaagtgt
    23641 tgttaaactg atattactca tttttcctcc aaaatcttag tttatcttga ttatagggca
    23701 attctaccct cttattctaa aagttctgat actttcagcc gaatcttttc ctaccattat
    23761 accatttttt tgatgatttt caaaatgaag gtctgttttc aaaaaagagt tgatttccca
    23821 actctttcct aacttctact ctttttccat caaaaaatca taaatttctt gcaccgtacc
    23881 cagcgccatc atttcttggt ctttaacggt ttgtttgaga ttttggtaaa tttgactttc
    23941 tcctatctcc cgctttggcg cctctttatt gactgtcatc acaccatctt ttatcgtcac
    24001 aaagcctagt tcttcaaata cttgaatcat cttgaccagc aagatttgtt gaatattaag
    24061 atatgcagcc aaatctttca gcttgtagcg aatatcaaac tctgggaact ggtaaatagt
    24121 cttgtacaat ttagcaaact gatctctagt cccataacct gtcagataat aggtcttgtc
    24181 aatatcattt ttgaaataga cagcagagaa atgctgttcc tgaaaaatgg tcttcagctg
    24241 agtaatatcc tctggaatgt tttttacgac aacagcttca ctagccgcaa gatttggcag
    24301 ttctccagga aaatccaaga ctggaacacc ttctggcaag actgcatttt ttccacgaat
    24361 gttaaaaagt tgaacacctt ccactcgcgc atccaccatc atcaactgga gggcagtttg
    24421 gccattccat tggttgacag acaatttaac cgctaactct agattcttgg tttgagaaaa
    24481 ctctgtcgcc catctgcctt gaccaaaggc taccacttca aaactcgcct cacccttgga
    24541 aattttcagc tttagatggg cattacctgc ccccatagta cgagcacttt cgacctgaaa
    24601 attcttgata taaaaaatag gtttctgatt atccattcca aaaggagcta aacgttcaaa
    24661 acttttgacc gtttccaagc taagtgcctc caaatccaac tcttcatcta ggtttaactt
    24721 attcttgcca ccagcatctg cacctttttc acgaacataa tcttccaaaa cctgagataa
    24781 atctgagagt tgctcaactt ccagcgtcat acccgctgca cctgcatgac ctccaaaggc
    24841 gatgaagagg tctcgatggg gatccagagc ttcaaaaata tcgaccgctt ccacactacg
    24901 agcactgccc ttggcacgac cgtcttctat attaagaaca atgactgtct gtcccaattc
    24961 ttccaataaa cgaccagcca cgattcctag aaccccagga ttccagcctt ccttggccaa
    25021 gacctgaacc ttcttctcag gatccaccat ggtcttggct tcttcataga tagactgaac
    25081 gatttccttg cgctcttcgt ttttctggtg aatcataagg gcaatctcat gcgcttcctc
    25141 atcatcaaat ccagtcaaca aatcaatggc aggattggga tcatccaagc ggcccaaggc
    25201 attcaaacga ggagcaatct ggaaaccaac cgtttcttct gttacttcgt tggcagcaat
    25261 cccagccatg tccagcattt cttgcagacc aatgcgctgg gtatgaccca acatttccag
    25321 accatattga actaagatac gattttcatc cgtcagactc accatatctg caatagttcc
    25381 aatagcgacc aaatcaagca attccacttg cacttcttct aacagggcac aagccaactt
    25441 gaaagcaact ccacaaccag ccaaatattt aaaaggataa tccgcatctg gatgttcagg
    25501 atggacaata gcataagcat ctggcagggt ttcaggcatg gaatgatggt ctgtcacaat
    25561 gacatctact cccatagact gagccaatgc aatagcctca tgaccagcaa ccccattgtc
    25621 caccgtcaca atcaaggaaa ttccttcttg ctcgataaag tatttataaa cactagcatt
    25681 agggccatag ccatcggtaa aacgatttgg caggtaaact cggcactcag caccaagttg
    25741 ttccaaactt tccttcacaa tagaagccga agtcatgcca tccgcatcat agtctccata
    25801 aacgagaata ttttcccctt cttcaatagc ctgacgaatc cgctccactg ccttgtccat
    25861 atcatggagc agataagcat catgtaagtc ctccaaggaa ggttctaaaa acttcttcag
    25921 actttcttgg tcctgaatcc ctctctcaaa caataaccga gccacctcag gacccagtcc
    25981 agccttcttg gctatctttg taaaatccgc atcttctacc tgcagggcaa actgccattc
    26041 ataagtaggt gttatcaaaa agacatccac tctttctaag aattctattg cttcattata
    26101 acatgattta gacgttttct ctatccagat tgctttttta taacatttta tagtatattg
    26161 aaactagaat agtacacctc tacttctaaa atattgttag aaatcgattt gactgtcccg
    26221 atcgatttgt cctgttctta tttcactata gtgaattttt tcagatatgg tttgacaaga
    26281 acattctttc attgtagaat cgtgttataa aatataacac aaaggagatc tctcatggct
    26341 ttagtagaat ttaaaaacgt cgaaaaatat tacggagact accacgcact ccgcaacatc
    26401 aatctccgtt ttgaaaaagg acaagttgtt gtcctgcttg gaccttctgg ctctgggaag
    26461 tccactctta tccgtacgat caatggttta gaggctgttg acaaaggaag tctcctagtc
    26521 aatgggcacc aagttgctgg tgccagccag aaagatttgg tacctcttcg caaggaagtc
    26581 ggcatggttt ttcaacattt taacctttat ccacacaaaa cggtgttaga aaacgtgaca
    26641 cttgcgccca ttaaagttct aggaattgat aaaaaagaag ctgaaaaaac cgcccaaaaa
    26701 tatctggaat ttgtaaatat gtgagacaag aaagattcct atcccgccat gctatctggt
    26761 ggacaaaaac agcggatcgc catcgctcgt ggtcttgcta tgcatccgga actcctcctc
    26821 tttgatgaac caacatctgc tcttgatcct gagactatcg gagatgttct agcagttatg
    26881 cagaaactgg cgcatgatgg gatgaacatg atcatcgtta cccacgaaat gggctttgct
    26941 cgagaggttg cggaccgcat tatctttatg gccgacggag aagttttagt agatacgaca
    27001 gatgtcgata acttttttga caatccaagc gaacctcgtg cccaacaatt cctcagcaaa
    27061 attatcaacc acgaaagtga caaagtcaaa taaggaggcg cctatgaaaa aaaattcttt
    27121 ttatcagcat tattgattag ccttttcggc cttgctgctg ccaaaccagt ccaggctgat
    27181 actagtatcg cagacattca aaaaagaggc gaactggttg tcggtgtcaa acaagacgtt
    27241 cccaattttg gttacaaaga tcccaagacc ggtacttatt ctggtatcga aaccgacttg
    27301 gccaagatgg tagctgatga actcaaggtc aagattcgct atgtgccggt tacagcacaa
    27361 acccgcggcc cccttctaga caatgaacag gtcgatatgg atatcgcgac ctttaccatc
    27421 acggacgaac gcaaaaaact ctacaacttt accagtccct actacacaga cgcttctgga
    27481 tttttggtca ataaatctgc caaaatcaaa aagattgagg acctaaacgg caaaaccatc
    27541 ggagtcgccc aaggttctat cacccaacgc ctaattactg aactgggtaa aaagaaaggt
    27601 ctgaagttta aattcgtcga acttggttcc tacccagaat tgattacttc ccttcacgct
    27661 catcgtatcg atgccttttc cgttgaccgc tctattctgt ctggctacac tagtaaacgc
    27721 acagaactac tagatgatag tttcaagcca tctgactacg gtattgttac caagaaatca
    27781 aatacagagc tcaacgacta tcttgataac ttggttacta aatggagcaa ggatggtagt
    27841 ttgcagaaac tttatgaccg ttacaagctc aaaccatcta gccatactgc agattaagga
    27901 ggacacccca tgatagattt atcatcttgg acagcctatt ttcaggattt tggacaattt
    27961 ttcaatggtt tcctctttac tcttgcccta gcgattggat cctttatcct cgccatggtc
    28021 ttaggaatct tctttggtgc catgtcaacc agtaaacgtc caattttacg cattttagct
    28081 cacatctttg tggaatttta ccaaaacact cccctcttgg tgcagtttgt tattgttttt
    28141 tatggcctac ctcttatcag tgaccatact atcatgattc caatttattg gacagctgtt
    28201 ctctgcatgg gactctatca cggcgcttat atcgctgagg ttattcgttc agggattcag
    28261 tctattccta gtggtcagat ggaggccgcc ttgtcgcaag gttttaccta tatcagtgcc
    28321 atgcgcttga ttatcttgcc tcagaccttc cgcatcattc tccctccatt gaccaaccaa
    28381 attgttaacc tcatcaagaa cacctctact gtagctatca tctctggagt agacttgatg
    28441 tttgtgacta agtcttggtc ggctctcaac ggaaactata tcccagcctt tttaggtgct
    28501 gctcttctct actttgctct atgcttccct gttgcccagt ttggtcgcaa gatggagcaa
    28561 gccaacaaaa aagcctattc actttaggag gttactatgg aatctatttt agaagtttta
    28621 accccagata acctagtctt tatctttaaa ggatttggct tgaccctcta tatttctctg
    28681 attgccatca tcctctctac tatcatcggt acggtgctag ctgtcatgag aaatggcaaa
    28741 aatcctgtct tacgcattat ttccagtatt tatatcgagt ttgtgcgcaa cgttcccaac
    28801 cttctctgga tttttactat ctttttggtg ttcaaaatga aatccacacc agcaggtatt
    28861 acagccttta ctctctttac atcagcagcc ttggctgaga ttattcgagg cggtctcaat
    28921 accgtagaca agggacagta cgaagcagga atgtcacaag gcttcacctc agcccaaatc
    28981 ctctactaca tcattctccc acaagccatc cgcaaaatgc taccagccat catttctcag
    29041 tttgttaccg tgattaagga taccagtctc ctctactctg ttatcgccct acaagaactc
    29101 tttggagcca gccaaattct catgggccgt tatttcgaac cagagcaggt cttcagtctt
    29161 tgcatcctga ttgccctcat ctacttcagc tttaacctag caatttctag cctgtctcat
    29221 atgctagcca aacgttggca acaagctgca gaataatact cttcgaaaat ctcttcaaac
    29281 cacgtcagct tcaccttgcc gtatatatgt tactgacttc gtcagttcta tccacaacct
    29341 caaaacggtg ttttgagcag cctgcggcta gcttcctagt ttgctctttg attttcatta
    29401 agtataaaca gccactctcc agttcaattg gagagttttt tgatgagagt agatatttat
    29461 agacctcaat ttgacaccat acattttcta tgataaaatg taacaaattc atttacaaca
    29521 aatcgaaatc taaatgaaat ggaattttct atgaaatcag tcaaaggact actctttatc
    29581 atagctagtt ttatcttgac tcttttgact tggatgaaca cttctcccca attcatgatt
    29641 ccaggactag ctttaacaag cctatctctg acttttatcc tagccactcg tctcccacta
    29701 ctagaaagct ggtttcacgg tttggagaag gtctacaccg tccacaaatt cacagccttt
    29761 ctctccatca tcctactaat ctttcataac tttagtatgg gcggtttgtg gggctctcgc
    29821 ttagctgctc agtttggtaa tcttgccatc tatatctttg ccagcatcat ccttgtcgcc
    29881 tatttaggca aatacatcca atacgaagct tggcgatgga ttcaccgcct ggtttaccta
    29941 gcctatattt taggactctt tcacatctac atgataatgg gcaatcgtct ccttacattt
    30001 aatcttctaa gttttcttgt tggtagctat gcccttttag gcttactagc tggtttttat
    30061 atcatttttc tatatcaaaa gatttccttc ccctatctag gaaaaattac ccatctcaaa
    30121 cgcttaaatc acgatactag agaaattcaa atccatctta gcagaccttt caactatcaa
    30181 tcaggacaat ttgcctttct aaagattttc caagaaggct ttgaaagtgc tccgcatccc
    30241 ttttctatct caggaggtca tggtcaaact ctttacttta ctgttaaaaa ttcaggcgac
    30301 cataccaata atatctatga taatcttcaa gccggcagca aagtaaccct agacagagct
    30361 tacggacaca tgatcataga agaaggacga gaaaatcagg tttggattgc tggaggtatt
    30421 gggatcaccc ccttcatctc ttacatccgt gaacatccta ttttagataa acaggttcac
    30481 ttctactata gcttccgtgg agatgaaaat gcagtctacc tagatttact ccgtaactat
    30541 gctcagaaaa atcctaattt tgaactccat ctaatcgaca gtacgaaaga cggctatctt
    30601 aattttgaac aaaaagaagt gcccgaacat gcaaccgtct atatgtgtgg tcctatttct
    30661 atgatgaagg cacttgccaa acagattaag aaacaaaatc caaaaacaga gcttatttac
    30721 gaaggattca agttcaaata agtaatcata ctctcctggg atttcccagg agagtttttt
    30781 atagccaaat gaaataaaac cggaacgatg gaattttggc attcaaatca attgataaga
    30841 atattttata gtggagtgaa ataggatacg aacaaattga ttaggaaaat caaatgaatt
    30901 tatagaaatc ttttagcagt tatgttgtcc tattctagtt tcaaaacgct atagaagcag
    30961 cattgtgcta gtctagattc agtttactat actaaaacga gtagcttgaa atcaaaaaac
    31021 ccaccctcac aggcaggttt tatctgtatt attcagctag attatgcttt accttctgaa
    31081 ccgaatacgt cgatacgttc ttcaaccgat gcttggatag cttttacacc gtcagccaag
    31141 aatttacgtg ggtcgaagag ttttttcttg tcgtattctg cttcgtttgc ttcgtagtca
    31201 cgagcaaatt tacgagttgc gttagcgaat gcgatttggc attctgtgtt aacgttaact
    31261 ttggcaacac caagtttgat agctgcttgg atttgctcat caggaatacc tgatccaccg
    31321 tgcaatacga ttgggaatcc tggaagagct tctgtcaatt tttgcaagtg gtcaaggtca
    31381 agaccttccc agtttactgg gtaagggccg tggatgttac cgataccagc tgccaagaag
    31441 tcgataccag tttcaaccat tgctttagcg tcttcgattg gagccaattc acctttaccg
    31501 atgattccgt cttcttcacc accgatagta ccaacttcag cttctactga gataccttta
    31561 gcgtgtgctt tttcaacaac ttctttagcc aatttaaggt tttcttcaac tggaaggtgt
    31621 gaaccgtcaa acatgattga agtataacca acttcgatac actcaagtgc atcttcgtag
    31681 tgaccgtggt caaggtggat agctactggt acagtgatac ccattgattc aacaaggtta
    31741 gcgatcaagt tgcgagcaac tttgtaacca cccatgtatt tagcagcacc cattgaagtt
    31801 tggatcaaaa ctggagcttt tttagcttct gctgcgcgca agatagcttg agtccactca
    31861 aggttgtttg tgttaaatcc accaactgca taaccgttgt cacgggctgc ttggacaaat
    31921 ttttctgctg aaacgattgc cattttatca ggcctcctgt atatttttat gggtcatccc
    31981 atttacattg ttcattttat cactttttgc caaaaaaatc tagtttttcc cgcagtttcg
    32041 attgattttc ttctaactcc atctatgtaa accctttctc tccctagtct tggacgactt
    32101 ttggaaaatc tataaagaag gttaaacgat tctcctccat ctcgaaacga taagctaatt
    32161 tttcatgttc taatagactc ttaaccacaa agagccccat accagacccc ttgaccttgc
    32221 gactggcatt gtcagaaaaa gactgggcta gtttttcttg ttcctctgag ctacagctat
    32281 tttcgataaa aagttctcct tctctttctc caattcgaac taagccacct ggaacagagt
    32341 gcttaatggc attgctgatg agattagaaa gaatcaactt cataactgat gggtttagat
    32401 aagcctgctg atgggtcaaa ctattgtcta tctggagctc tctttccttg gctagcaagg
    32461 cataatcttt gaccagattt tgcgtcatct ggaggaggtc aattgtttcc ctatcatctc
    32521 gcaattcctg cacagaagag agggaaagta tctgcagaac atggtgattg agttcatcca
    32581 caatccccaa ggcaactccc agatactggt ctctatcctt ataacgaccg atattctctc
    32641 tcatattttc gattaggatt ttcaaactag ccagcggtgt tttcaattca tgagaagctc
    32701 ctcgtaggaa ttcgaccttc atcttctcca gctggagaat ggcttcattc ttttcatgca
    32761 agtccgcaat aacagtcaag agatgctggt agaggctatt gatttgttcc ttgagattac
    32821 ctatctcatc cttagaatcc acgcgcaatc gcacttggga atccaggtcc atcatccgac
    32881 gggtcacccg cttgatttcc aagatcggtg caacaatagt ccgagcgtag atgtaggcca
    32941 ccaagaggga aatcagaaag gaggccagca aggtataggg aagaaactgg agactgattt
    33001 gctccgcttc cttttgtaaa tccatggaag ctagaaactg gagaatcata gtagcaccgt
    33061 cttgcgtttt cacctcgcgc tcctcaataa agagagaggt tgtctggcgg tctgtgtcca
    33121 gaggaagact gtccttgact tctaacttgt cctcggtcat ctcacctttg acggtcccct
    33181 tgatatcact agtctgggaa tacaagtcta acacttgctc gatactctgc ctatctttcc
    33241 cttctaggga ctgggcaatg gctgttgcct tttgaccaat ggtttcctga cgatgactca
    33301 gataagtcga aggaaaaaga aaataaatag ctaaatgaag gcagataacc agaacactaa
    33361 atatcgagaa ggtatagata aatatctttg caaataaacc tgttcgtttc attttcgctc
    33421 caatttataa ccaacattgc gcacagtgag gatacaatcc aagtctagct ttttccgcaa
    33481 ttccttgata taaacatcaa taacacggtc aaagggaacc tcatctgtcg ctttccagac
    33541 ggcatcgata atctgagatc gagtcaaggc ccggccttca tttttcacta gatagtccag
    33601 aatttccaac tctttggcat tgataggcac ttcttgacct gcgatgcttg cactgtagct
    33661 ttcaaagtcc accttggtat ccttgtaaga aaagattcgt cctgtatcgt agtagcgctt
    33721 gaaaatcgcg tccaccctca cttttaaaag ggagagggag aaaggttttt ccagatagcc
    33781 atctgccaaa gaggcaaagg cactcatctt gtattcctca tcttgaaaag ctgtcaacat
    33841 caagacagga acctgactgg ttttacgaat ctcagctagg acttctaagc cgttgagctt
    33901 gggcatctgg atatccagta aaaccagggc cacctcatag ctagaaaatt gctccagagc
    33961 ttcctgaccg tccgctgcct caatagtttc atagccacaa tccgtcaaat aatcactgac
    34021 cccctcacgg atcatctctt catcttctac aattaaaatt ttcatacttt aactgctctc
    34081 tattttttat ttttcttaga ataaatacct actctatttt ctattatagt ctcttgctgg
    34141 ccttttgtct gcaagcaact gaccactaga taaaacgttg tgaaattcct ttctcataaa
    34201 ttccataact ttagtatatt atatttaagc actaaagtac aaagaaagca actgaaagca
    34261 atgattttca ccactgcttt cggatttatt ttgaattgtt aaatagccat tcctatccac
    34321 tattcttgaa tagaaacaca agatgcaatc tttattctag actcattttt tcaaatttat
    34381 tcaccatcca gcaagagctc ttttggttgt tttctaagga gattgcttga agcaagcgcc
    34441 ataacgagaa ccactagaac caaggcaagg acaaaaatga tgataaagtc tgatgtctga
    34501 atggaaatgt ctaggctcga caaggtcttg ctaaagccat ctacttctgc accaccacca
    34561 aggttagagg cttgagccgc cttactagcc tgtttggcaa cacctgaagt cacattggca
    34621 aggacagtgt ttccaattgc acgggcagtg taattagcta ggaagtaagc agaaactaga
    34681 gcagggatag caatcaagat agattcggtg atgaattgac ccaagatact tgcctgcttg
    34741 aggccgatag agaggagaat tcccacttcc ttgcgacggg cgttgatcca aaggctgagc
    34801 aagagggcaa ggaggagaac tgagaagctc aagctacccc agaagaggag gttggccatc
    34861 ttgtacatac cagagataga ttgctcaaga gctgggtagt tagaggagct cttgacgagt
    34921 gtgtagctct tccagttgat accactgatg ccattcaact ctttcataac atcatccaag
    34981 ttcttgtctg ctgttacaaa gaaggttgcg tccccataaa tggctgtgtc ttctgtgtat
    35041 ccataaagtt ttgcagcagt gtgaatgtct gtaatagctg tgttttcgta aagttcttgt
    35101 gagtaggtta ctgctgactt attatgacca tcaaagagtc ccttgattgt cacttcaact
    35161 gtttccttgg ctcctttttc attatctgca tcgtagatat tagagtccag tttaaccttg
    35221 tcccctactt tccagccgtg tttggctgcc aagtccttgt gcaagaggat tttatccttg
    35281 tcgtcgttgg ttaagtgctc tccttcgact agtttataag aaccagagac aaacttgtct
    35341 tctttagagg agtcattgac acctgtaatc atcaagctac ttccaaaacg cttggcacga
    35401 tcagcagtga gattcttctt ggtttctggc gtttcaatca ggtcatatcc agtcaaatct
    35461 ccgatagcgt tgatacgttt gacataagac tcgatggcct tgttttcggt gatttttttg
    35521 atgtcttcac ccttgatatt cccagcacca cgaggcgttc cttggttgac gcgacgattg
    35581 atttgcatgg agaagctatt agtgatattt ttaaaggtct cctgagaagc cttggcagta
    35641 gctcccttga ttgacaagcc gaccaaactc aagctcgcca tgaggagaat aatcaggaag
    35701 atgacaatcg atttgaaaaa cttccttgta acataggcaa atgcgttgtg taacatagat
    35761 tccctttcta gattttgttt taatcattct atcaaaataa gctcaaatta tttactagta
    35821 ttgcgcgttt cagtcagttt cttatccttt aattcaagtg taatatctga cgcttgtgcc
    35881 acttctttac tgtgagttac gacaatcaca catttacctg ttttctgggc aagtgatttg
    35941 agtagttcga caatatctcc agcagtttta ggatccagat ttcctgttgg ctcatcagct
    36001 agaataactg gagcttctga gaccaaactg cgagcaatgg caacacgttg ctgttgacca
    36061 cctgataact ggagaacatt ccgcttgatc tggctttcat ccaaaccaag ctcaagaagt
    36121 gtatccttgc ttgccttttt gttgaccaag cggatatttt ccagcggaga aagataatct
    36181 atcaagttat aattttgaaa gaccagggaa atatggtgca tgcgatggta agaatagccc
    36241 ttcttacgaa tatcctctcc ttgaaaaagg atagaacctt caacaggact atctagacca
    36301 gcaagtaggg acaagagtgt ggattttcct gctcctgact ccccaataat actgtaaaat
    36361 tttccaggtt caaaattata atcgatctga tataggactg cttcagcagt attcttataa
    36421 cggtaggtaa catcttgtaa ttgtaataaa gtcatgattt ctccttctta actaatagat
    36481 gataaaattt ctttcggtga ttttctaaat aagaatagga aacaaagggc tacagataag
    36541 caactaagca gaactagaaa aacataggat tctgcaaaag ataagatgct agttgataaa
    36601 ctgcttgctt tggctagtgt atcttgtaag cttgcctgat ctccacttgc tagtagagtt
    36661 tggagtagat aacttgtgat tccgtttcct gcaacaaatg ctggaagcaa agctccaaga
    36721 gataccaaaa ctacctctaa acagaattgt aggaagatcg agctcttgcc ttttccaagt
    36781 gcaagtaaaa tccccacttc atagacccgt tctctcaacc agagagacaa aaccagaatt
    36841 aaggctccag ctcctgctat caacatccca taaaggaaga tggtcaagaa ggtttggaaa
    36901 gttgcaactg agtctttgat ttgttcaaaa gccttgtttt ccttttcgac ttggtagcct
    36961 tgattttcca aggccaagtt ttctacctgc ttcatgagtc cgtccatttc cttaggattt
    37021 tctacataga agcgtgctgc actgacttga gcttcactat tgcccaaaag ggtttggcta
    37081 ctttcatagt ctgtaaagac ttgattttca ctgaagtcag aagacaagcc tgtgaatttc
    37141 tcttgttttt taccagaaaa gatgccgata atctcaaact ctactgtttg tccttttcca
    37201 gattcagact gaccagcatc caagccaatc ttgtcatgaa gtgaaagacc gttcttctta
    37261 gccaattctt cgtggataag gattttcttg gaatcccctt tttgaaggtg tcgcccttct
    37321 tttagattga aagccgaact ggtaaaggtt acatccttgg atgaatcctc aagagccgtt
    37381 aagctaacca agttattgtc tgcagctgat aaatcatcac gctccacgct ctgctcacca
    37441 gtcactgctt ccttgtcttt tagttttgcg accgtctcaa gttcaggaga gacattttcc
    37501 agccccttaa tcttgcttac agatgctagg tctgacaact tgaatgtctg accattctct
    37561 atcttcttaa tagaaaaaga tgtattgagt gatttataaa gattgctttc tactgttttg
    37621 ttggacttca tcagagtcaa acaggctgaa attccggcca ataagaccaa taaaatcaga
    37681 aataaaataa aacttctcag tcgctttctg ctgacataag cccaagatct ttggattgga
    37741 ttcatttgtc acctccatat ttgtaagact attataaaac ccaaatatga aatgtttatg
    37801 aaatacgaaa aaaaa
//
LOCUS       DAVAZT010000015        37667 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVAZT010000015 DAVAZT010000000
VERSION     DAVAZT010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37667
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.015"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            108..896
                     /gene="codY"
                     /locus_tag="VQT45_000705"
     CDS             108..896
                     /gene="codY"
                     /locus_tag="VQT45_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HET2359060.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            896..1471
                     /locus_tag="VQT45_000706"
     CDS             896..1471
                     /locus_tag="VQT45_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET2359061.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDFFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            1553..1638
                     /locus_tag="VQT45_000707"
     tRNA            1553..1638
                     /locus_tag="VQT45_000707"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1587..1589,aa:Leu,seq:aag)
     gene            1921..3051
                     /gene="ugpC"
                     /locus_tag="VQT45_000708"
     CDS             1921..3051
                     /gene="ugpC"
                     /locus_tag="VQT45_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HET2359062.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(3198..3344)
                     /locus_tag="VQT45_000709"
     CDS             complement(3198..3344)
                     /locus_tag="VQT45_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359063.1"
                     /translation="MEIKEQTRKLAVSCSKYIFEVADKTDEISNHTYGKATLTWFEEI
                     FEEY"
     gene            3552..4310
                     /locus_tag="VQT45_000710"
     CDS             3552..4310
                     /locus_tag="VQT45_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET2359064.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGLSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKVLTGEMTLMKLSGMIYDEGWLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            4397..4909
                     /locus_tag="VQT45_000711"
     CDS             4397..4909
                     /locus_tag="VQT45_000711"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HET2359065.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            5091..6035
                     /locus_tag="VQT45_000712"
     CDS             5091..6035
                     /locus_tag="VQT45_000712"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HET2359066.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            6044..6721
                     /locus_tag="VQT45_000713"
     CDS             6044..6721
                     /locus_tag="VQT45_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HET2359067.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVRSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            6819..7577
                     /locus_tag="VQT45_000714"
     CDS             6819..7577
                     /locus_tag="VQT45_000714"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HET2359068.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            7615..9120
                     /gene="lytC"
                     /locus_tag="VQT45_000715"
     CDS             7615..9120
                     /gene="lytC"
                     /locus_tag="VQT45_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HET2359069.1"
                     /translation="MSVTFFIGEERLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSTEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAESDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTGTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPHYSGKKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            9616..10134
                     /locus_tag="VQT45_000716"
     CDS             9616..10134
                     /locus_tag="VQT45_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HET2359070.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            10264..10770
                     /locus_tag="VQT45_000717"
     CDS             10264..10770
                     /locus_tag="VQT45_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HET2359071.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            10770..10940
                     /locus_tag="VQT45_000718"
     CDS             10770..10940
                     /locus_tag="VQT45_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359072.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            10972..12204
                     /gene="clpX"
                     /locus_tag="VQT45_000719"
     CDS             10972..12204
                     /gene="clpX"
                     /locus_tag="VQT45_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HET2359073.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            12213..12800
                     /locus_tag="VQT45_000720"
     CDS             12213..12800
                     /locus_tag="VQT45_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HET2359074.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            12811..13191
                     /locus_tag="VQT45_000721"
     CDS             12811..13191
                     /locus_tag="VQT45_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HET2359075.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            13243..14133
                     /gene="rapZ"
                     /locus_tag="VQT45_000722"
     CDS             13243..14133
                     /gene="rapZ"
                     /locus_tag="VQT45_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HET2359076.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            14130..15107
                     /locus_tag="VQT45_000723"
     CDS             14130..15107
                     /locus_tag="VQT45_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HET2359077.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            15104..16015
                     /gene="whiA"
                     /locus_tag="VQT45_000724"
     CDS             15104..16015
                     /gene="whiA"
                     /locus_tag="VQT45_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HET2359078.1"
                     /translation="MSFTVAVKEEILGQHHLSRHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLVNGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(16049..17017)
                     /locus_tag="VQT45_000725"
     CDS             complement(16049..17017)
                     /locus_tag="VQT45_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET2359079.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWTLAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            17153..18010
                     /locus_tag="VQT45_000726"
     CDS             17153..18010
                     /locus_tag="VQT45_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HET2359080.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            17997..18776
                     /locus_tag="VQT45_000727"
     CDS             17997..18776
                     /locus_tag="VQT45_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HET2359081.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            18800..20152
                     /locus_tag="VQT45_000728"
     CDS             18800..20152
                     /locus_tag="VQT45_000728"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HET2359082.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAIQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            20226..20600
                     /locus_tag="VQT45_000729"
     CDS             20226..20600
                     /locus_tag="VQT45_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HET2359083.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            20602..21450
                     /locus_tag="VQT45_000730"
     CDS             20602..21450
                     /locus_tag="VQT45_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET2359084.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            21727..22494
                     /locus_tag="VQT45_000731"
     CDS             21727..22494
                     /locus_tag="VQT45_000731"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HET2359085.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDDMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            22506..23690
                     /locus_tag="VQT45_000732"
     CDS             22506..23690
                     /locus_tag="VQT45_000732"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HET2359086.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGDILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            23687..25558
                     /locus_tag="VQT45_000733"
     CDS             23687..25558
                     /locus_tag="VQT45_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2359087.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDSKIRPFFGHYTDYLDEKAFETDMANQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(25701..26885)
                     /gene="mntE"
                     /locus_tag="VQT45_000734"
     CDS             complement(25701..26885)
                     /gene="mntE"
                     /locus_tag="VQT45_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HET2359088.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPISEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            27189..29885
                     /locus_tag="VQT45_000735"
     CDS             27189..29885
                     /locus_tag="VQT45_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HET2359089.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            29898..30689
                     /gene="yghU"
                     /locus_tag="VQT45_000736"
     CDS             29898..30689
                     /gene="yghU"
                     /locus_tag="VQT45_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HET2359090.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            30805..31215
                     /locus_tag="VQT45_000737"
     CDS             30805..31215
                     /locus_tag="VQT45_000737"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET2359091.1"
                     /translation="MEKKIVKDILFLSQVSHPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGMQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            31227..32822
                     /locus_tag="VQT45_000738"
     CDS             31227..32822
                     /locus_tag="VQT45_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359092.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            32989..33153
                     /locus_tag="VQT45_000739"
     CDS             32989..33153
                     /locus_tag="VQT45_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HET2359093.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            33232..33960
                     /gene="yaaA"
                     /locus_tag="VQT45_000740"
     CDS             33232..33960
                     /gene="yaaA"
                     /locus_tag="VQT45_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HET2359094.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(34011..35495)
                     /locus_tag="VQT45_000741"
     CDS             complement(34011..35495)
                     /locus_tag="VQT45_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2359095.1"
                     /translation="MRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILERLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEGYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYISGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL"
     gene            35711..>37667
                     /locus_tag="VQT45_000742"
     CDS             35711..>37667
                     /locus_tag="VQT45_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET2359096.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAVSVLLGTALVLGAAASV
                     QTVQAEENKQETTNSISVGRGEAATKPAEVSASNKEKTYAAPTVANPVETTPVKTGEV
                     TKPAEKVEEAKDKKEEVTHQDAIDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADASEAELSAAESSIQSSIIGLELRSNSNKGTVSETPVAKKANIVEAKEETN
                     PAATTDRSAVDSAVLPTSTAAKVETTSAPASINEILKPGLSLSDARQNPAIRKEDVDR
                     GYSGFRAAPAPTNQPVTNLGNNTVFTDISRGSHTFRGNGNSRRGNPIHFDVTTTRVRN
                     RVDFSIRYSGPGEFVNNNFILDKGNGFGEPSRATVSTPKLRDQVKNISKGGNFVSHSG
                     YSLEAAVETSTNQTIKFSLPIANPNGDLSVRLRPVTFNVGQGESGSATSNDPYSNSNY
                     YFREKPLLLDANPNGGTNNKTVSEDIDFQTVYLPTSKLPEGQTRLVREGEKGQRQIIY
                     KVHQLGNETILGLPISNSVIKEVKPRIMQIGVAKDLIDTVKPRVDQNKVGDTNNLTFY
                     LDNDGNGVYTEGVDELVQKIAIKDGAKGEKGDRGERGLTGAQGAKGEKGDRGERGLTG
                     AQGAKGEKGDRGERGLTGAQGAKGEKGD"
BASE COUNT        11317 a         6899 c         8566 g        10885 t
ORIGIN      
        1 tttaattaaa ttgtaagtca atgcaagtca ataaggaatt ttcagataat tattgaaaaa
       61 gagacgtttt tatgttataa tgatagcgat taaattcgag gtgaaaaatg gcacatttat
      121 tagaaaaaac tagaaaaatt acatcaattt tgaaacgctc agaggagcag ttgcaggatg
      181 agctccctta caacgctatt acgcgtcagt tagcggatat tattcattgc aatgcctgca
      241 ttatcaatag taagggacgt ctgcttggct attttatgcg ttataaaaca aatacagatc
      301 gcgtagagca attcttccaa actaagattt tcccagatga ctacgttcaa ggggctaata
      361 tgatttacga aacagaagca aacttgcctg ttgagcatga tatgagtatt ttccctgttg
      421 agagtagaga tgattttcca gatggcttga cgactattgc accgattcat gtatcgggga
      481 ttcgccttgg ttctttgatt atttggcgta atgataaaaa attcgaagat gaggacttgg
      541 ttcttgttga gattgccagt accgttgttg ggattcagct tcttaacttc caacgtgaag
      601 aagatgagaa aaatattcgt cgtcgtactg ctgtcaccat ggcggtcaat accctttctt
      661 actccgaact ccgtgctgtt tcagcaattt taggggaatt aaatggaaat gaagggaagt
      721 tgactgcgtc agtgattgca gatcgtatcg gaatcactcg ctctgtgatt gtcaatgctc
      781 ttcgtaaact tgagtctgcg gggattattg aaagtcgctc acttggaatg aagggaacct
      841 atcttaaggt cttgatttca gatatttttg aagaagtgaa gaaaagagat tactaatgac
      901 aaaggcttta atttcgattg attatacaga agattttgtt gctgatagtg ggaagctgac
      961 agcaggtgct ccagctcagg cgatttcgga tgccatcagc aaggtaactc gattagcttt
     1021 tgaacgagga gattatatct tctttactat tgatgctcat gaagaaaacg attttttcca
     1081 tccggaaagt aagttatttc ctcctcataa tctgattggg acgagtggac ggaatttata
     1141 tggagatttg gggatctttt atcaagagca tggttcagac agtcgtgtct tttggatgga
     1201 taaacgccat tactcagctt tttcagggac tgacctagat attcgtttga gagagcgtag
     1261 agtgtctacc gttatcttaa caggtgtctt gacggatatc tgtgtcctac atacagctat
     1321 agatgcctat aatctaggat atgacatcga gattgttaaa ccagctgttg cttccatctg
     1381 gcctgaaaat catcaatttg ccctaggtca tttcaaaaat acactcggag ctaagttagt
     1441 agatgaaaat ctaaatgaac tttctgagta acctggttgg tgaaaatgaa aaaatttgaa
     1501 aaaaagtgtt gacaagcatc ccaaaagttg atatactagt aaagtaatcg atgcggggat
     1561 ggcggaattg gcagacgcgc aggactaagg atcctgtgac cgctttaggt cgtgagggtt
     1621 caagtccctc tctccgcata ggaaaagagt tagctaaagc tagctctttt gtatttctct
     1681 aaaaaattag aatccagtca aatgtagtgg agaatcagcg aaaatatggg aaaactgttc
     1741 cttgtttctg cttttgtcat agaagaataa taaagattat cttcttcaaa ttctccgata
     1801 ttctctaaag ttttgtgcaa gttgcacaga acttttttat ttttttggtc atcttgccat
     1861 agaaatataa agcgttttca tctataatat aattatcaaa agacaaaagg agttcacctc
     1921 atggtagaat tgaatcttaa aaatatttac aaaaaatatc caaacagcga acactattca
     1981 gttgaagatt tcaacttgaa catcaaagat aaagaattta tcgttttcgt aggaccttca
     2041 ggatgtggta aatcaactac actccgtatg attgctggtc ttgaagacat tacagaaggt
     2101 actgcatcta tcgatggcgt ggttgtcaac gacgtagctc caaaagaccg tgatatcgcc
     2161 atggtattcc aaaactacgc tctttaccca cacatgactg tttatgacaa catggctttc
     2221 ggtttgaaat tgcgtaaata cagcaaagaa gacattaaca aacgtgttca agaagcagct
     2281 gaaatacttg gattgaaaga attcttggaa cgtaaaccag ctgacctttc aggtggtcaa
     2341 cgtcaacgtg ttgccatggg gcgtgcgatt gtccgtgatg cgaaagtatt cttgatggac
     2401 gaacctttgt caaacttgga tgccaaactt cgtgtatcaa tgcgtgctga aatcgctaaa
     2461 attcaccgtc gtatcggagc tacaactatc tatgtaactc acgaccaaac agaagcgatg
     2521 acacttgcag accgtatcgt tattatgtca gctactaaga accctgctgg tacaggtact
     2581 atcggacgtg tagaacaaat cggtactcct caagaagttt acaaaaatcc agttaacaaa
     2641 ttcgttgcag gattcatcgg aagcccagct atgaacttca tcaacgtgaa attggttggt
     2701 agcgaaattg tttctgacgg tttccgtttg aaagtgccag aaggagcatt gaaagttctt
     2761 cgtgaaaaag gctacgaagg aaaagaattg atctttggta tccgtccaga agacgtgaat
     2821 gcagaacctg ctttccttga aacattccca gactgtgttg taaaagcgac tatctctgta
     2881 tcagaactgc ttggttcaga atctcacctt tactgccaag ttggtaaaga cgagtttgtt
     2941 gcaaaagttg atgctcgtga ctacttgcaa acaggtgcaa cagttgagct tggatttgac
     3001 ttgaacaaag cacacttctt cgatgtagaa actgaaaaaa caatctacta aaataaataa
     3061 aattcaaagc actacaagaa aagatatctc tttatcaatt gtagtggaga gatatcagtt
     3121 aatctaggga gagaaacaaa atgcttctct cctttttgct agggaagtca tattatgcat
     3181 ctatattgtg atgctcttta atactcttcg aaaatctctt caaaccacgt caacgtcgcc
     3241 ttgccgtacg tatgattact gatttcgtca gttttatctg caacctcaaa gatgtacttt
     3301 gagcagctta cggctagttt cctagtttgc tctttgattt ccattgagta ttatttgtgg
     3361 gtaccatcta caagtgaagc tatatgcgta aactacgtga gcaattgaat tcgaactaga
     3421 gaggtaataa taaatttatg ctatagttat ggtgacttgt atgcttttga ttctagttta
     3481 tcaaataata gattagaatt gtcagataat atcattttgt gttataatga agaaaaaaca
     3541 gaggtgttca aatgtcagaa gcaggtcata agtttttagc aaaattgggg aaaaaacgct
     3601 tacgtccagg tggaaagcgt gctacagatt ggttaattgc agaaggagga ttgtcaaaag
     3661 aaaagagaat actagaggtt gcgtgtaata ggggaactac agcaattgag ttggcacagc
     3721 gttttggttg caagataact gctgttgata tggatgctca agctttagaa gtggctaaaa
     3781 aatctgctgg aacggcaggt gttgctcatt taatcagttt tgaaagagca aatgcaatga
     3841 aacttcctta tcaagatgct agttttgata ttgttataaa tgaagctatg ctgactatgc
     3901 aagccgatca agctaagaaa aaatgtgtaa tggaatatct aagggtatta aaacctggag
     3961 gtcttctttt gacacatgat gtgcttctta aggaagctaa agagtctatc agacaggaat
     4021 tatcacaagc aattcatgta aatgtaggtc ctttaactca agatggttgg gaacaggtga
     4081 tgatagaatc aggttattgt gatgtgaaag tattgactgg tgaaatgaca ttaatgaaat
     4141 tatcgggtat gatttatgac gaaggttggc taggaacttt gaaaatttgt gtaaatgctt
     4201 gtaaaaagga gaatagaaag cagtttttaa ctatgtataa aatgtttgct aagaataaac
     4261 agaaattggg ctttattgcg atggctagtt ataaatcgtc aaaacgttag ataattattg
     4321 aagttaactt ttcctttttt ctttcttaaa aaatatgcta taatagagag tgaaaaactt
     4381 tgaaagaaag aaaaagatga atttaaaaga ttacattgca acaattgaaa attatccaaa
     4441 ggaaggcatt accttccgtg atattagtcc tttgatggct gatggaaatg cttatagcta
     4501 cgctgttcgt gaaatcgttc agtatgctac tgacaagaaa gtcgacatga tcgtgggacc
     4561 tgaagctcgt ggatttatcg tgggttgtcc agttgccttt gagttgggaa ttggttttgc
     4621 gcctgttcgt aagccaggta aattgccacg cgaagttatt tctgctgact atgaaaaaga
     4681 gtacggtgtc gataccttga ctatgcacgc ggatgccatt aagccaggtc aacgtgttct
     4741 tattgtagat gaccttttgg cgacaggtgg aactgttaag gcaactatcg agatgattga
     4801 aaaacttggt ggtgttatgg caggttgtgc cttccttgtt gaattggatg aattgaacgg
     4861 ccgtgaaaaa atcggtgact acgactacaa agttcttatg cattattaat gaaaacagtc
     4921 cctagggctg ttttctctac actaggatat aaaaatagac tataactagt tagagaaaaa
     4981 ctataattga aaactatatc ttcttgcagt ataataaaag gactaagtgt ttgagatttg
     5041 tcttcaaaca catgcaatta ttcctgagag agtacagtta ggagagggtt atgccgattc
     5101 gaattgataa aaaattgcca gctgttgaga ttttacggac agagaatatc tttgtcatgg
     5161 atgatcaacg tgctgcccac caagatatcc gtcctttgaa gattttaatt ttaaatctca
     5221 tgccacagaa aatggtcaca gagacccagt tgttgcgtca cttggctaat acacccctac
     5281 aactggatat tgattttctc tatatggaga gccaccgttc taaaacaact cgttcagagc
     5341 acatggagac cttctataaa acttttcctg aagtcaagga tgagtatttt gatgggatga
     5401 tcatcacggg tgctccagtt gagcatttac catttgagga agtggactat tgggaggaat
     5461 ttaggcagat gcttgagtgg tctaagacac atgtctattc gacccttcat atctgttggg
     5521 gggctcaggc tgggctttat ctgcgctatg gtgtagaaaa ataccagatg gacagtaagc
     5581 tatcaggtat ttatcctcag gacaccctaa aagagggtca ccttctattt agaggctttg
     5641 atgatagcta tgtatcccct cattcacggc acacggagat ttctaaggaa gaggtcttaa
     5701 acaagaccaa tctcgagatt ttatcagaag gacctcaggt tggggtttct attttggcca
     5761 gtcgtgattt acgagaaatt tatagttttg gtcatttgga gtatgaccgt gataccttgg
     5821 caaaagagta ttttcgagat cgtgatgcag gtttcgaccc acatattcca gaaaattact
     5881 ttaaagatga tgatgttaat caggtacctt gtctttgttg gtcttcatct gcagccctct
     5941 ttttcagtaa ttgggtaaac catgcggtct atcaggagac gccttttgat tggagaaaga
     6001 tagaagatga tgcatctgca tatgggtatt tataagagga attatgacat atttagacgc
     6061 ttttaaatca ggtaccttgg ttttaccgag tgccctgctc ttgcatttta aggaactctt
     6121 tccttctagc gacgattttc tggtttggca atttttctat ttgcaaaata cgacaggctt
     6181 agaagaaatg tcgccaagcc agattgctga aaggattggc aaggaaattt cggatgtcaa
     6241 ccagtccatt tctaatctga cggaaagggg actgctccag tatcgtacta tcgaattaaa
     6301 tggcgaaatt gaattgctct ttgatgctag tttggccttg gaacgtttgg atgacctgtt
     6361 tggagcagtt cgttcaagtt cagaccagct aacacctcaa aaccagctca aggatttggt
     6421 ggaaaccttc cagcaggagt tgggacgatt gttgacgcct tttgagattg aggatttgac
     6481 caagacacta aaggaagatg gaaccagtgc tgacttgatt aaggaggctc ttcgtgaagc
     6541 tgttttgaat ggaaaaccaa actggaagta cattcaggcg attttgagaa actggcgcca
     6601 tgaaggaatc aagagtgtgg ctcaaattga ggccaagaga gcagaaagag aagcaagcaa
     6661 tcctcagttg acacaggtat ctgcagattt cagaaatgcc atggatctct ggaaggatta
     6721 atccatgcaa gtaggcttga aatccgagta agatttgcaa gctgtgtata attgtgatag
     6781 aataaataga aaataaattg aaaaaagagg tatgtgaaat gtcacgtaaa ccatttatcg
     6841 ctggtaactg gaaaatgaac aaaaatccag aagaagctaa agcattcgtt gaagcagttg
     6901 catcaaaact tccttcatca gatcttgttg aagcaggtat cgctgctcca gctcttgatt
     6961 tgacaactgt tcttgctgtt gcaaaaggct caaaccttaa agttgctgct caaaactgct
     7021 actttgaaaa tgcaggtgct ttcactggtg aaactagccc acaagttttg aaagaaatcg
     7081 gtactgatta cgttgttatc ggtcactcag aacgccgtga ctacttccat gaaactgacg
     7141 aagatatcaa caaaaaagca aaagcaatct ttgcgaacgg tatgcttcca atcatctgtt
     7201 gtggtgaatc acttgaaact tacgaagctg gtaaagctgc tgaattcgta ggtgctcaag
     7261 tatctgctgc attggctgga ttgactgctg aacaagttgc tgcctcagtt atcgcttatg
     7321 agccaatctg ggctatcggt actggtaaat cagcttcaca agacgatgca caaaaaatgt
     7381 gtaaagttgt tcgtgacgtt gtagctgctg actttggtca agaagtcgca gacaaagttc
     7441 gtgttcaata cggtggttct gttaaacctg aaaatgttgc ttcatacatg gcttgcccag
     7501 acgttgacgg tgcccttgta ggtggtgcgt cacttgaagc tgaaagcttc ttggctttgc
     7561 ttgactttgt aaaataatca gtaagtagca aaagctaggt ggaacagcat tcagatgtct
     7621 gttacatttt ttataggaga ggaaagattg aaaacaaaaa ttggattagc aagtatctgt
     7681 ttactaggct tggcaactag tcatgtcgct gcaaatgaaa ctgaagtagc aaaaacttcg
     7741 caggatacaa cgacagcttc aagtagttca gagcaaaatc agtcttctaa taaaacgcaa
     7801 acgagcacag aagtacagac taatgctgct gcccactggg atggggatta ttatgtaaag
     7861 gatgatggct ctaaagctca aagtgaatgg atttttgaca actactataa ggcctggttt
     7921 tatattaatt cagatggtcg ttactcgcag aatgaatggc atggaaatta ctacctgaaa
     7981 tcaggtggat atatggccca aaacgagtgg atctatgaca gtaattacaa gagttggttt
     8041 tatctcaagt cagatggggc ttatgctcat caagaatggc aattgattgg aaataagtgg
     8101 tactacttca agaagtgggg ttacatggct aaaagccaat ggcaaggaag ttatttcttg
     8161 aatggtcaag gagctatgat gcaaaatgaa tggctctatg atccagccta ttctgcttat
     8221 ttttatctaa aatccgatgg aacttatgct aaccaagagt ggcaaaaagt gggcggaaaa
     8281 tggtactatt tcaagaagtg gggctatatg gctcggaatg agtggcaagg caactactat
     8341 ttgactggaa gtggtgctat ggcgactgac gaagtgatta tggatggtgc tcgctatatc
     8401 tttgcggcct ctggtgagct caaagaaaag aaagatttga atgtcggctg ggttcacaga
     8461 gatggtaaac gctatttctt taataataga gaagaacaag tgggaaccga acatgctaag
     8521 aaaatcattg atattagtga gcacaatggt cgtatcaatg attggaaaaa ggttattgat
     8581 gagaacgagg tggatggtgt cattgttcgt ctaggttata gcggtaaaga agacaaggaa
     8641 ttggcgcata acattaagga gttaaaccgt ctgggaattc cttatggtgt ctatctctat
     8701 acctatgctg aaaatgagac cgatgctgag agtgacgcta aacagaccat tgaacttata
     8761 aagaaataca atatgaacct gtcttaccct atctattatg atgttgagaa ttgggaatat
     8821 gtaaataaga gcaagagagc tccaagtgat acaggcactt gggttaaaat catcaacaag
     8881 tacatggaca cgatgaagca ggcgggttat caaaatgtgt atgtctatag ctatcgtagt
     8941 ttattacaga cgcgtttaaa acacccagat attttaaaac atgtaaactg ggtagcggcc
     9001 tatacgaatg ctttagaatg ggaaaaccct cattattcag gaaaaaaagg ttggcaatat
     9061 acctcttctg aatacatgaa aggaatccaa gggcgcgtag atgtcagcgt ttggtattaa
     9121 gcgatgattt gaaagaggga tgtgatagta gcaccctctt tttctttgtt ttatgatagt
     9181 tcatcctcga gtaaattcaa gttcttgctc ggaaatgaag cttatatagt agattgaata
     9241 tagacaaata ccttgtgatt ggtaaaacat tttagaaatt catttacctt tcctaatcga
     9301 cttggtttca tcttatttca atctattata gtattgggga atttcttcaa accacatcag
     9361 cttggtcagt tctacctgcg acctcaaaac ttgtgctttg gtcaagctgg gtttagtttc
     9421 ctagtttgct gatggatttc cattgactat aagcatccaa ccctcttttt gtcttctaaa
     9481 gaattcttaa attatcagtc tattgcaact tttctcatat aagttctttg tcttgctatt
     9541 ggttttcctt agtagtatac taaggtagta atcattaaga agtggttaca aaaaataatg
     9601 aatgaggtaa agaaaatggt agaattgaaa aaagaagcag taaaagacgt aacatcattg
     9661 acaaaagcag cgccagtagc attggcaaaa acaaaggaag tcttgaacca agctgttgct
     9721 gatttgtatg tagctcacgt tgctttgcac caagtgcact ggtatatgca tggtcgtggt
     9781 ttccttgtat ggcatccaaa aatggatgag tacatggaag ctcttgacgg tcaattggat
     9841 gaaatcagtg aacgcttgat tacactcggt ggaagcccat tctctacatt gacagagttc
     9901 cttcaaaata gtgaaatcga agaagaagct ggtgaatacc gtaatgttga agaaagcttg
     9961 gaacgtgttc ttgttatcta ccgttacttg tcagaacttt tccaaaaagg tttggatgtc
    10021 actgatgaag aaggtgacga tgtgacaaac ggtatctttg caggcgctaa aactgaaaca
    10081 gataaaacaa tttggatgct tgcagccgaa cttggacaag cacctggttt gtaagaaata
    10141 aggaaacata gataaatctg taggaaattt cttacagatt ttttctattt tgtaagctat
    10201 tccaaaccag tctttttttg agttttttga taaaatagta ctatcagtga aaaggatgga
    10261 agcatgacta agaaaatcgt agctatttgg gcccaggatg aagagggtgt gattggtaag
    10321 gaaaatcgtc tgccttggca tttgccagca gaattgcagc actttaaaga aacaactctg
    10381 aatcatgcta tcttgatggg gcgtgtgacc tttgatggga tggggcgtcg cttgcttcca
    10441 aaacgggaaa ccttgatttt gacgcgtaat ccggaagaaa agatagatgg ggttgctact
    10501 tttcaggacg tccagtctgt tcttgactgg tatcaggctc aagaaaagaa tctctacatt
    10561 atcggtggga agcaaatttt tcaggctttt gaaccttacc ttgatgaagt gattgtcact
    10621 cacattcatg ctcgggtgga aggagatacc tatttccctg aagaacttga cttgtctctt
    10681 tttgagacag tttcaagcaa attttacgcc aaagatgaga agaatcctta tgattttacc
    10741 atccaatacc gcaagagaaa ggaagtctaa tggaacggag tttatttggt ctattcacgg
    10801 cttttctgtg tttcatctgc tttctggcag gagcacaagc ttttcgtaaa aagcgttacg
    10861 ggctttctat cctcctttgg ttaaatgcct ttaccaatct ggtcaatagt attcatgctt
    10921 tttacatgac cttattttag atagaatgac agtatagaat ggaaggaaat catgtctaca
    10981 aatagaaaaa atgatatgat ggtttattgc tcattttgtg gcaaaaacca agaagaagta
    11041 caaaaaataa ttgctggcaa caatgctttt atttgtaatg aatgcgtgga gttagctcag
    11101 gaaatcattc gagaagaatt ggttgaggaa gtcttggcag acttgtctga ggtgccaaaa
    11161 ccaattgaac tcctccatat cttgaaccac tatgtaattg gtcaagatcg tgccaagcgt
    11221 gccttggcag tggcggttta taaccactac aaacgcatca atttccacga tacacgcgaa
    11281 gagtcagaag atgtggattt gcagaagtca aacattttga tgattggccc aactggttca
    11341 gggaaaactt tccttgccca gaccttggct aagagcttga atgtaccttt tgctattgcg
    11401 gatgcgacag ctctgacgga ggctggttat gtgggtgagg atgtggaaaa tatactcctc
    11461 aaactcttgc aggttgctga ctttaacatc gaacgtgcag agcgtggcat tatctatgtg
    11521 gatgaaattg acaagattgc caagaagagt gagaatgtgt ctatcacacg tgatgtttct
    11581 ggtgaagggg tgcaacaagc ccttctcaag attattgagg gaactgttgc tagcgtaccg
    11641 cctcaaggtg gacgcaaaca tccacaacaa gagatgattc aagtggatac aaaaaatatc
    11701 ctcttcatcg tgggtggtgc ttttgatggt attgaagaaa ttgtcaaaca acgtctgggt
    11761 gaaaaagtca tcggatttgg tcaaaacaat aaggcgattg acgaaaacag ctcatacatg
    11821 caagaaatca tcgctgaaga cattcaaaaa tttggtatta tccctgagtt gattggacgc
    11881 ttgcctgttt ttgcggctct tgagcaattg accgttgatg acttggttcg catcttgaaa
    11941 gagccaagaa atgccttggt gaaacaatac caaaccttgc tttcttatga tgatgttgag
    12001 ttggaatttg acgacgaagc ccttcaagag attgctaata aagcaatcga acggaagaca
    12061 ggggcgcgtg gacttcgctc catcatcgaa gaaaccatgc tagatgttat gtttgaggtg
    12121 ccgagtcagg aaaatgtgaa attggttcgt atcactaaag aaactgtcga tggaacggat
    12181 aaaccgatcc tagaaacagc ctagaggtga ctatggaact taatacacac aatgctgaaa
    12241 tcttgctcag tgcagctaat aagtcccact atccgcagga tgaactgcca gagattgccc
    12301 tagcagggcg ttcaaatgtt ggtaaatcca gctttatcaa cactatgttg aaccgtaaga
    12361 atctcgcccg tacatcagga aaacctggta aaacccagct cctgaacttt tttaacattg
    12421 atgacaagat gcgctttgtg gatgtgcctg gttatggcta tgctcgtgtt tctaaaaagg
    12481 aacgtgaaaa gtgggggtgc atgattgagg agtacttaac gactcgggaa aatctccgtg
    12541 cggttgtcag tctagttgac cttcgtcatg acccgtcagc agatgatgtg cagatgtacg
    12601 aatttctcaa gtattatgag attccagtca tcattgtggc gaccaaggcg gacaagattc
    12661 ctcgtggtaa atggaacaag catgaatcag caatcaaaaa gaaattaaac tttgacccaa
    12721 gtgacgattt catcctcttt tcatctgtca gcaaggcagg gatggatgag gcttgggatg
    12781 caatcttaga aaaattgtga ggaaaagaaa atggcaaaaa caattcatac agataaggcc
    12841 ccaaaggcta tcggacccta tgttcaagga aaaatcgttg gcaacctttt gtttgctagc
    12901 ggtcaagttc ccctatcccc tgaaactggg gaaattgtag gagagaatat ccaagaacag
    12961 acagagcaag tcttgaaaaa catcggtgct attttggcag aagcaggaac agactttgac
    13021 catgttgtca aaacaacttg cttcttgagc gatatgaacg actttgttcc ttttaatgag
    13081 gtttaccaaa cggccttcaa agaggaattc ccagctcgtt cagctgtgga ggtagctcgt
    13141 cttcctcgtg atgtaaaagt cgaaattgaa gtcatcgcag agattggata agctagttga
    13201 agtttggtgt tgccaaactt cttttgatat aaggagaaaa agatgacaaa gaaacaactt
    13261 cacttggtga ttgtgacagg gatgagtggc gcagggaaaa ctgtagccat tcagtccttc
    13321 gaggatctag gttatttcac cattgataat atgccgccag ctctcttgcc taagtttttg
    13381 cagctggttg aaattaagga agataatcct aagttggctt tggtagtgga tatgcgtagc
    13441 cgttctttct tttcagagat tcaagctgtt ttggatgagt tggaaaatca agatggtttg
    13501 gatttcaaaa tcctcttttt ggatgcggct gataaggaat tggtcgctcg ttacaaggaa
    13561 accagacgga gtcacccact agcagcagac ggtcgtattt tagatggaat caagttggaa
    13621 cgtgaactct tggcaccttt gaaaaatatg agccaaaatg tggtggatac gactgaactc
    13681 actccacgtg aactgcgcaa aacccttgca gagcagtttt cagaccaaga acaagcccag
    13741 tctttccgta tcgaagtcat gtctttcgga tttaagtatg gaatcccgat tgatgcggac
    13801 ttggtctttg atgtccgttt cttgccaaat ccctattatc taccagaact gagaaaccaa
    13861 acgggtgtgg atgaacctgt ttatgattat gtcatgaacc atcctgagtc agaagacttt
    13921 tatcaacatt tattggcctt gattgagccg attctgccaa gttaccaaaa ggaaggtaag
    13981 tccgttttga ccattgctat gggatgtacg ggtggacaac accgtagtgt ggcatttgct
    14041 aaacgcttgg cgcaggactt atccaagaat tggtctgtta atgaagggca tcgcgacaaa
    14101 gaccgcagaa aggaaacggt aaaccgttca tgagaaaacc aaagataacg gtgattggtg
    14161 gagggactgg aattcccgtc attctaaaaa gtctgcggga aaaagatgtg gaaatcgcag
    14221 ctatcgtgac ggtggcagat gatggtggtt cttcaggtga actccgaaaa aatatgcaac
    14281 agttgacacc gccaggtgat cttcgtaatg tccttgtggc catgtcggat atgcctaagt
    14341 tttatgagaa ggtctttcag tatcggttct ctgaggatgc cggagccttt gctggccatc
    14401 cattgggaaa tctcatcatt gctggcttgt cagaaatgca gggttcaacc tataatgcca
    14461 tgcagttatt gagcaaattt ttccatacaa cagggaaaat ttatccttcc agtgaccatc
    14521 ctttgaccct tcatgcagtc tttcaggatg ggacagaagt ggctggagag agtcatattg
    14581 tagaccatcg aggcataatt gacaatgtct atgtgaccaa tgccctaaac gatgatacgc
    14641 ctctggccag ccgtcgagta gtgcagacca tccttgaaag tgacatgatt gtcctagggc
    14701 caggttccct ctttacctct attttgccca atatcgtgat taaggaaatt gggcgggctc
    14761 ttttggaaac taaggcagaa attgcctatg tctgcaatat catgacccaa cgtggggaga
    14821 cggaacactt tacagatagc gaccacgtgg aagtcttgca tcgtcacctt ggtcgccctt
    14881 ttatcgacac tgtcttggtg aatattgaaa aagtgcctca ggaatacatg aattccaacc
    14941 gttttgatga atacttggtg caagtggaac acgattttgt aggtctttgt aagcaagttt
    15001 cgcgcgtgat ttcatctaac ttccttcgtc tggaaaatgg cggtgccttc cacgatggag
    15061 atttgattgt ggacgagttg atgcgcatta tacaggtgaa aaaatgagtt tcacagtagc
    15121 agtaaaagaa gaaatcctgg gccaacacca tctgagccgg catgaattat ctgccattat
    15181 caaaatgtct ggtagcatcg gtctctcgac ttcgggcttg actttgtcag ttgtgacaga
    15241 aaatgccaaa ctggcccgtc acctctatga gtcctttctc catttctatg aaatcaaatc
    15301 tgaaattcgt caccaccaac ggagcaatct tcgcaagaat cgcgtctata ccgtttttac
    15361 agatgaaaag gtgcaggatt tgttaagtga tttgcacttg gcagactctt tctttggcct
    15421 ggaaacaggt attgatgagg cgattttatc ggatgaggaa gcaggtcgtg cctatctctg
    15481 tggcgctttc ttggtaaatg ggagcattcg tgaccctgag tcaggcaagt accagttgga
    15541 aatcagttct gtttatctgg accacgcgca aggaattgcc tcccttctcc aacagttttt
    15601 actggatgcc aaggtgcttg agcgcaagaa gggggctgtg acctatctcc agcgagcaga
    15661 agacattatg gacttcttga tagtaatcgg agccatgcag gcacgtgatg attttgagcg
    15721 ggttaagatt ttgcgagaaa cccgtaacga cctcaatcgg gctaataatg ccgagacagc
    15781 taatatcgct cggacagttt ctgccagcat gaagaccatt aacaatatca gtaaaataaa
    15841 agatatcatg ggcttagaaa atttgccagt agatttgcag gaagtggcgc aactgaggat
    15901 tcagcaccca gactactcta tccagcagtt agcagatagt ctcagcaccc ctctgaccaa
    15961 aagtggtgtc aatcacagac tcagaaaaat caataagata gcggatgaat tataaaacca
    16021 cgaatcctat gtgactcgtg gttctttttt ataaactggt agagtgtttt ggttgtactt
    16081 tttgttcagg gtcaatgtag ttgatagcgt tgttgacagc agttggagct tctccgaggc
    16141 ctgtcgcaat cagatcaatt tttccgtcat agtagcagca gtcaccgata gcatagatac
    16201 ctgcttggct ggattcctgt ttgctgttga cgataatctt gtgacggttg aggtcgagcc
    16261 cccagttttt aaggttaccg acagaagatt tgaaaccata gttgacaaag aggtggtcta
    16321 ggtcaatggt ttcagtttca tcagatttga cttttgtgat ttcaagttta tcaagtgttt
    16381 ttccatttcc aaggagttgg ctaggggcga atggtgtctt gatggttaca gatgattctt
    16441 gcaaggcttg aacactgtgt tccaaggcac ggaaattatc tctgcggtga acaagggtag
    16501 ttggtgcgat tttttcaaaa gccaaagtcc aatccacagc cgagtctccc ccaccaagaa
    16561 tcgtcacttt tttaccagcg tattgctgaa tgttagaaac gtggtagtgg atattttcat
    16621 agccctcaac cccttcaagt tccagcggac gtggtttgaa ggcaccgcca cccatagcga
    16681 tgataactgt tttagtcagg tgacttcctt tagaagttgt gatggcaaat tcttcttctt
    16741 gtttgtcaat ctcaagaacc gtttcattga gatgaatagg ggtatcaaat ccatttagct
    16801 gttcaatcaa gcggttagtc aactcttctc cagtcaggtt tgggaagcct ggtacgtcta
    16861 ggatttcctt ttcagggtag agaatagcag gttgtccacc tagctgggga agagagtcga
    16921 tgatttgaac cttggcttgg cgtaggtggg cataaaaggc tgcaaaaagc ccgacaggac
    16981 caccacccac aatggtaata tcatagagtt gagacatagt ttctcctttg ttttttctag
    17041 tcagtttatt ttatcatatt tttgttcaat gtaaaatgga ctaggatagg gaaaaaaatg
    17101 ccagaaaatg gtataatagg acgaaagtgt tttgataggg aggatatcag ggatgaattt
    17161 tcaacaatta tccaatttgc aatattggac cagtttgttt gcaagtccat ggacgatagc
    17221 tatcaatctg attgatattt tgattgttgc ttatatttta taccatttta caaaagctat
    17281 tgcaggaacc aagattatga ttttggtacg tggagttttg gtatttattt tagctcaaat
    17341 ccttgcaaat atgattggtt tgactacgat ttcttggtta atcaatcaaa ttattactta
    17401 tggggttatt gcggcggttg ttatcttctc tccagagatt cggactggtt tggaacgttt
    17461 gggaagagcg acagatttct tttccaatgc ccctattagt gctgaggaac agatgattcg
    17521 tgcctttgtt aagtctgttg aatacatgag tcctcgtaaa atcggggcct tggttgctat
    17581 tcagcgtgta cgtaccttgc aggagtatat ttcgacagga attcccttgg atgctaagat
    17641 ttctgcagaa cttctcatta acatttttat tcccaacact cccctacatg acggtgcggt
    17701 gattatcaaa gaagaacgta tcgctgtgac gtctgcctat ctgcccttga caaaaaacac
    17761 agggatttcc aaggaatttg ggaccagaca ccgggcggct atcggtttat cagaagtctc
    17821 agatgccttg acttttgtcg tatcagagga aacgggagga atttcgataa cctataatgg
    17881 aaggtttaag cacaacctaa cacttgatga atttgaaaca gaattacgtg aaatcttact
    17941 tccaaaagag gaagtaggtc ttagttttaa agaacgattg ctaggaggat ggaaacatga
    18001 aaaaaaatag tttatatatc atatcctcac tcttttttgc ttgtgtctta tttgtctatg
    18061 ctacggcgac gaattttcaa aacagtacca gtgctaggca ggtaaaaacg gaaacctata
    18121 ctaatacagt aacaaatgtc cctattgaca tacgctataa tagtgataag tattttatta
    18181 gcggttttgc ttcagaagta tcagtggtct tgactggtgc aaatcgccta tcgctagcta
    18241 gtgaaatgca agaaagtaca cgtaaattca aggttactgc tgacctaaca gatgccggtg
    18301 ttggaacaat tgaagttcct ttgagcattg aagatttacc caatgggctg accgctgtgg
    18361 cgactccgca aaaaattaca gtcaagattg gtaagaaggc tcagaaggat aaggtaaaga
    18421 ttgtaccaga gattgaccct agtcaaattg atagtcgggt acaaattgaa aatgtcatgg
    18481 tgtcagataa agaagtgtcg attacgagtg accaagagac attggataga attgataaga
    18541 ttatcgctgt cttgccaact agcgaacgca taacaggtaa ttacagtggt tcagtacctt
    18601 tgcaggcaat cgaccgcaat ggtgttgtct taccggcagt tatcactccg tttgatacaa
    18661 taatgaaggt gactacaaaa ccagtagcac caagttcaag cacatcaaat tcaagtacaa
    18721 gcagttcatc ggagacatct tcgtcaacga aagcaactag ttcaaaaacg aattaaaaat
    18781 agaaaaggat tttataacaa tgggtaaata ttttgggact gatggagtcc gtggagaagc
    18841 taacctagaa ctaacaccag aattagcctt taaactagga cgttttggag gctatgttct
    18901 tagtcaacat gaaacggaag cgccgaaagt ctttgtagga cgtgacacac gtatttcagg
    18961 ggaaatgcta gaatcggcct tggtggcagg tctcctttca gtagggattc acgtatacaa
    19021 acttggtgtc cttgcaacac cagcagtagc ttacttggtt gaaactgaag gagcaagtgc
    19081 tggtgtcatg atttctgcta gccacaatcc agctcttgat aacggaatca agttctttgg
    19141 cggtgatggc ttcaaactag atgatgaaaa agaagcagaa attgaagcct tgctagatgc
    19201 tgaggaagac actcttcctc gtccaagtgc agaaggctta ggaattttgg tagattatcc
    19261 agaaggcttg cgtaagtatg aaggatacct tgtttcaact ggaactcctc ttgatggaat
    19321 gaaggttgcc ttggatacag ctaatggagc agcttctacc agtgcccgtc aaatctttgc
    19381 agaccttggt gcccaattga cggttatcgg ggaaacacca gacggtctta acatcaacct
    19441 taatgttggt tcaacacatc cagaagccct tcaagaagtg gtcaaagaaa gtgggtcagc
    19501 tattggtttg gcctttgatg gagacagtga ccgcttgatt gctgttgatg agaatggtga
    19561 catcgtcgat ggtgacaaga ttatgtacat catcggaaaa tacctttctg aaaaaggaca
    19621 attggctcaa aatacaattg tgacaactgt tatgtctaac cttggtttcc acaaggcctt
    19681 gaatcgcgaa ggtattaaca aggcagttac tgcagttggt gaccgctacg ttgttgaaga
    19741 aatgagaaaa tcaggttaca accttggtgg tgaacagtct ggtcacgtta tcttgatgga
    19801 ttacaatacc acaggtgatg gtcaattatc agcaattcaa ttgactaaaa tcatgaagga
    19861 aactggtaag agcttatcag agttggcggc agaagtaacg atttatccac aaaaattagt
    19921 taatatccga gtggaaaacg tcatgaagga aaaggccatg gaagtgccag ctatcaaggc
    19981 catcatcgag aagatggaag aagaaatggc ggggaacggc cgtatccttg ttcgtccaag
    20041 tggaacagag cccctcttgc gtgttatggc agaagcgcct acaacagaag aagtggacta
    20101 ctatgttgat actatcacag atgtagttcg tgctgaaatt gggattgact aaatcctaga
    20161 aaactagatg aaaataaaaa attatggtac aatagcttat aatattgtag ccgatggaga
    20221 aagacatgaa tcttaaacgt gaacaagaat ttgttagtca gtatcatttt gatgcacgta
    20281 attttgaatg ggaaaatgaa aatggagctc ctgaaaccaa ggtggatgtg aatttccaat
    20341 tgctccaaca tgaccaagaa aatcaagtga cttccttgat tgtcattttg agctttatga
    20401 ttgtatttga taagtttgtc attagtggaa caatctcaca agtaaaccat atcgatggcc
    20461 gtattgtcaa tgaaccaagt gaattgaacc aagaagaggt ggaaaccttg gctcgtccat
    20521 gtttgaacat gctcaatcgt ttgacttacg aagtgactga aattgcatta gacttaccag
    20581 gaattaattt ggagttctaa tatgaaatta gctgttttca cagattcctc tgcttatctc
    20641 agtgaagaga ccttgcaaag agaagacttg tttgtcttgg atattcctgt caatattgat
    20701 ggtgaggaat atgtcgaagg catcaatctg tctgctgagg aattttacca aaaaatggct
    20761 caggcttctg aattgcctaa gaccagtcaa ccaagtattg ccaagttaga tgagatctta
    20821 acttcgctca aagaacaagg ctatacacat gccttggggc ttttcctatc ttctggaatt
    20881 tcaggttttt accaaaatat ccagtatatg gtcgatgact atgagggctt aaccattgct
    20941 ttcccagaca ctttgattac aagtgctccc ctaggcatca tggttgaaag cgtctttaat
    21001 tggcgtgatc agggcgatga ttttgccagc attcaggata agctagccat tcaaatcagc
    21061 cgtacgtcag cctttatcat ggtagatgac ttggatcatt tggtaaaagg tggacgcctt
    21121 tcaaatgggg ctgccatttt gggcaatttg cttagcatta agccaatcct ttattttaac
    21181 gatcaaggtg tgattgaagt ttacgaaaaa gttcgtactg aaaagaaggc caccaagcgc
    21241 ttaattgaaa ttatcaagga aacaacggct tcaggtcaat accgggtcat tgtcattcat
    21301 gggaatgctc ctgaaaaggc tgaagaattg cgtcagcact tgcttgattt tggcttgggt
    21361 tcggatgttt cacttgctac atttggtagt gtcattggaa cgcacctagg agcaggaagt
    21421 attgctctgg gttatattcc agtgatttag ttggcgcttc taggctagtt aagatgcctt
    21481 gtatcttaga aattgaacac ggactacctg cctcttgaaa aaagatgcct gtcttgcctt
    21541 tcgtggaaag tcagtgccat tccctatttt tcagaggcag ctaaggtcct ttgtatcttg
    21601 ataattgaac acgcctggaa ccctgtgtga aaaagatagt tcttccaaga agtagacact
    21661 tcttgattgg aattcctatt ttcactttgt gttcttacgg actttgtatc ttagacagga
    21721 gtagagatga gtattcgagt aattattgcc ggttttaagg gaaagatggg ccaggctgct
    21781 tgtcagatgg tattgactga tccagacttg gacttggtgg cagttttgga tccttttgag
    21841 tctgagtcag aatggcaggg tattcctgtt ttcaaggata aggctgattt agctggtttt
    21901 gaagcggatg tctgggtaga ttttactact ccagctgttg cctacgaaaa tacacgtttt
    21961 gctcttgaaa atggctttgc tccagtagtt ggaacgactg gtttcacgag tgaagaaatt
    22021 gcagagctaa aagaattttc tcgtgcccaa gacttgggtg gcctgattgc ccctaacttt
    22081 gccttgggtg ctgtcttact catgcaattt gcgacgcagg ctgccaaata tttcccaaat
    22141 gtggagatta ttgagctcca tcatgacaag aaaaaggatg ctccgagtgg aacagccatt
    22201 aaaacagctg agttgatggc agaggttcga gagtccattc agcaaggcgc agcagatgag
    22261 gaagagctga ttgctggtgc tcgtggtgct gactttgatg atatgcgcat ccactcagtt
    22321 cgtttgccag gcttggtagc tcatcaggaa gtcatctttg gcaatcaggg agaagggttg
    22381 accctccgtc atgactccta tgatcgcatc tccttcatga caggagtcaa tttgggaatt
    22441 aaagaagttg tcaagcgtca tgagcttgtc tatggattag aacacttatt atgagattaa
    22501 cgcaaatgcc ttctgaattt cagaaggctt taccagtatt agaaaaaatt aaagaagcag
    22561 gctttgaggc ttattttgtt gggggctctg ttcgagatgc ccttctccat agccctatcc
    22621 acgatgtgga tattgcgacg tcttcttatc cagaagagac caagcagatt tttccgcgaa
    22681 cagccgatat cggaatcgag catggaaccg tcttggtctt agatggggat gaggagtatg
    22741 aggtaacaac ctttcggaca gaggatgtct atgtggacta tcgcagaccc agtgcggttt
    22801 cctttgtacg atcgctagaa gaagacctca aacgccgtga tttcacagtc aacgcctttg
    22861 ccttggatga gacaggagaa atcgttgact tgttccatgg tttagaagat ttggaaaagc
    22921 aagtcttgcg agcagttgga gtggctagtg agcgtttcaa cgaagatgct ttacggatta
    22981 tgcgtggttt ccgttttcag gctagtcttg gttttgcact tgagccagaa acatttaaag
    23041 ctatgaagac cttgacgccg cttttggaga aaatttctgt agagcgtacc ttcgtcgagt
    23101 ttgataaact cttgctggct ccattttgga gaaggggctt ggcttccatg attgagagtc
    23161 aagcttatga ctatctccct gatatggcat ctagccagga caagctcaac agactgtttg
    23221 atttggagac tgattttact tttgaatcct ctgaacaagc ctgggcggct ttactatggg
    23281 ctttggagat tgaaaatgcg cagtcatttt tgaaatcttg gaagacctca cgccagtttg
    23341 ccaagcaagt tcaggatttg ctgattattt tggctctgcg tgaaaatgga gaattgagta
    23401 agcgagattg ttatcgcttt gacatagatt tgcttttaca ggctgaaaat cttcgtcaag
    23461 ctcaaggaaa agaagtcaac ccacaagcca tcacagaaaa ataccaaagc ttgactatcc
    23521 atgacaagaa agagattcag attaatggcg atattttgat caaggaatat ggctatcagc
    23581 caggcccaga cttgggagag attttaacag agattgagtt tgccattgtc gatggagaat
    23641 tggagaataa tcgtgaagcc atccatgctt acctgaggga gaaaaaatga gtgattttat
    23701 cgttgaaaaa ctaagtaaat ccgttggtga caagaccgtt tttagggata tttcctttat
    23761 tatccatgac ttagacagaa ttggtttaat cggtgtcaat gggactggca agaccaccct
    23821 tttggacgtc ctttctggtg tttctggatt tgatggggat gtcagtcctt tttcagctaa
    23881 aaatgattac cagattggtt acttgactca ggatcctgat tttgatgata gaaagacagt
    23941 tttggatacg gttctatcta gtgaactcaa ggaaatccag ctcattcgtg agtatgaatt
    24001 gattatgctc gactatagtg aggacaagca ggcgcgtttg gaacgtgtca tggcagagat
    24061 ggactctctc caagcttggg aaatcgaaag tcaggtcaag accgttctta gcaaattggg
    24121 cattcaagac ttatctactc ctgttgggga attgtcaggt ggtctgagaa gacgggtaca
    24181 gttggcacaa gtcttacttg gcaaccacga cctcttgctt ttggatgagc cgaccaacca
    24241 tctggatatt gcgattattg agtggctgac cctctttttg aaaaattcta agaagaccgt
    24301 cctttttatc actcacgatc gttatttctt agacgctttg tcaacacgga ttttcgagtt
    24361 ggatcgtgca ggcttgaccg agtaccaggg caattaccag gactatgttc gcctaaaggc
    24421 ggaacaggat gagcgcgacg cggctcttct tcacaaaaaa gaacaactct acaaacaaga
    24481 actggcctgg atgcgcagac aaccgcaggc gcgtgcgacc aagcagcagg cccgtatcaa
    24541 tcgattccat gatctgaaaa aggaagtttc aggcagtagt gctgagacag acttgaccat
    24601 gaactttgaa accagtcgga ttgggaagaa agtcatcgag tttcaggctg tttcctttgc
    24661 ctatgaaaac aagcctattt tgcaagattt taatctcttg gtgcaggcca aagaccgtat
    24721 cggaatcgtt ggggacaatg gtgttggaaa atcaaccctg ctcaacttga ttgcaggaag
    24781 tcttgagcca actaaaggac aagttgtgat tggggaaact gttcgcatcg cctatttctc
    24841 tcagcaaatt gagggtttgg atgaaagcaa gagagttatc aattacctgc aggaagtggc
    24901 agaagaggtc aagaccagtg gcggttctac gacttcgatt gcagagttgc tggagcagtt
    24961 ccttttccca cgttcgacgc atggaacctt gattgagaaa ttgtcagggg gtgagaaaaa
    25021 acgtctttat ctcctcaaac tgcttttgga aaaaccaaat gttcttcttt tagacgagcc
    25081 aaccaatgac ctagatattg caactttgac agtcttagag aatttcttgc aaggttttgc
    25141 aggtcccgtt ttaacagtca gtcacgaccg ctatttcttg gataaggtag cgaccaagat
    25201 tctcgctttt gaggatagca agattcgtcc tttctttggt cattacaccg actatcttga
    25261 tgaaaaagct tttgaaacag atatggccaa tcaagtgcaa aaggtcgaaa aggaaaaagt
    25321 ggtcaaggtt cgagaagaca agaaacgtat gacctaccaa gaaaagcagg agtgggcaag
    25381 tattgaaggt gatattgaaa ccttggaaaa acgtatcgct gctattgaag aggaaatgca
    25441 ggctaacggc tctgactttg gtaagctggc tactctccaa aaagaattgg atgagaaaaa
    25501 tgaagcactc cttgaaaaat acgaacgcta tgagtatctc agtgaatttg atagttaaga
    25561 ctattcgaaa atcaaagtgc aaactatgtc ggcttcacat tgccgactca agtacagcct
    25621 gtgaccggct tcctaatttg cactttgatt tttattgagt ataaaagaat agaaaaatcc
    25681 cgtctcatga aaggatttct ctattctttt ttggtttctt gatgaaagat attttgccag
    25741 gtttcgtggc gacgccagat actggtatgg atgataccat ctaactcata gcagatgagt
    25801 ttggtttttt gactgatgga agtaatttga atgtccttga tagcagaatt taactctttt
    25861 ttggtcttat aagcctcttt atccatctgc tctccatctt ggcgaatata gacaaaatca
    25921 tcagtcaaga gttcttctag ttggtttcct tggtcaatca attgttcacg cataagcaat
    25981 tttttataga cattgtctaa aatttcatcc tcagagatag gtgctggttc gatatggaca
    26041 tcggtatcaa agacgccaaa acgctcctcc agcatagact cgacctgatc cgcgatttca
    26101 tggctttcaa aaacagacaa gtcaggattc atctctagtg taatatccag gtagatgttg
    26161 ctaccgtagg tgcgacctct ttgcgatttg accttgctga ttttgggaat ttccatgata
    26221 gccttttggt agtcctcgag caggcggtcg tcaaagccat ctgaaagact aaaggaagac
    26281 tcgatgaaga tatcataggc agtcttcaag ataaagaaag tgatgatgat agcaaccagt
    26341 ttatccacaa tcggataatt gaaactacta gctaggatgg caatggcggt tccaagtgag
    26401 gtaacagcgt cagaaagatt gtccttagca gctgccttca gcgccttgga gttggatttc
    26461 ttactgaggc gagtattgta gagatagacc acaaacataa tcgctgcaga aatgattcct
    26521 agagttgcac caagaggatc aatgaccgtt tcttcccgac tgagaatctt ttgaatggta
    26581 tctcttagaa catcgaaacc gacatagaac atgatgatag aagtgatcaa gcttgccaaa
    26641 tcttcaatct tccaatgacc aaaacggtgg tcacggtctg caggctggcg cgccatccga
    26701 atcccgatta agagggccac atttccaatg atgtccgata cgttattaaa accatcggcc
    26761 accaaactgg atgaatgaag gagatgacca gctgctaatt tggctgcaga caagatcaaa
    26821 taggtcgaaa tactgataat ggctccacgc tcagctaact tgagatttga gatagattgc
    26881 ttcattcaac ttcctttcta gtcacatagc attctaccat tatactggtt ttcaaggaaa
    26941 aattcaaata aggcagtttt tactctttga aaactcccca aaatttggta taatggtact
    27001 actcaaggga gtagctggca gaaacctgtg atagtgtcgt cattccgaat tttatgctga
    27061 aaagtatgct ttccggccct atcttaaaca gcgagacttg ttatgattaa caggtctctt
    27121 tttgtttgtc gtgaaaagat atgacagaaa gagagtctgt tttgcacaca atgtcaagga
    27181 ggagacacat gtcaaaagaa caaaaacgcc aagcgtttta tactcagagc cctgaagagg
    27241 tcttgcaggc tgtggatgcg accgagcaag gtttgtcatc aagtgaggcg gaaaagcgcc
    27301 ttgctgaatt tgggcacaat gaactcgaag aaggcgagaa acgatcaatc ttggtcaaat
    27361 tcatcgagca atttaaggat ttgatgatta tcatcctagt tgcggcagca atcttgtcag
    27421 tcgtgacttc tggtggggaa gatatcgcag atgccattat catcctagct gtggttatca
    27481 tcaacgctgc ctttggtgtt taccaagaag gaaaagctga agaagctatt gaagccctca
    27541 aatccatgtc tagtccagtt gcccgcgttc ttcgtgatgg acacatggca gagattgact
    27601 ctaaagaatt ggtaccaggc gatatcgttg cccttgaagc aggtgacgtg gtaccagcgg
    27661 acctacgttt gatagaagcc aactctctta aaattgaaga agcagccttg acaggtgaat
    27721 ctgtaccagt cgaaaaagac ttgtcagtcg agcttgcgac agatgctggt attggtgacc
    27781 gtgtcaacat ggccttccaa aactcaaacg taacctatgg tcgtgggatg ggtgttgttg
    27841 tcaatacagg tatgtacact gaagttggtc atattgctgg tatgcttcaa gatgcggatg
    27901 agactgatac accactcaaa caaaatttga acaacctttc taaggtcttg acctatgcta
    27961 tcttggtcat tgcccttgtt acttttgtag tgggtgtctt cattcaaggg aaaaatccac
    28021 ttggtgagtt gttgacttct gttgcccttg ccgttgcagc cattccagaa ggacttcctg
    28081 ctatcgttac catcgttctt tctcttggta ctcaagtttt ggccaaacga cattccatcg
    28141 ttcgtaagtt gccagcagtt gaaacacttg gttcaactga aatcatcgct tctgataaga
    28201 ctggtacgct gactatgaac aagatgacag tcgaaaaagt cttctacgat gcggttctac
    28261 atgactcagc tgatgatatt gaactaggtc ttgaaatgcc actacttcgt tcagttgtct
    28321 tggccaatga tacgaaaatc gatgtggaag gtaacttgat tggtgaccca accgaaacag
    28381 cctttatcca atatgccttg gacaagggct atgatgtcaa aggtttctta gagaaatatc
    28441 ctcgtgtagc tgaattgcca tttgactctg accgtaagct catgtcaaca gttcacccat
    28501 tgccagatgg tcgtttcctt gtagcagtca agggtgcgcc agaccaactc ttaaaacgtt
    28561 gtcttcttcg tgataaggct ggggatattg ctccgattga tgagaaggtt acaaatctca
    28621 ttcatacaaa caattctgaa atggctcatc aagccttgcg tgtccttgca ggtgcttata
    28681 agattatcga tagtattcca gaaaatctca cttctgaaga gcttgaaaat gatttaattt
    28741 ttactggttt gattgggatg attgaccctg aacgtcctga agccgctgag gctgttcgtg
    28801 tggctaagga agcgggaatc cgtccaatta tgattacagg tgaccaccaa gacacagcgg
    28861 aagccattgc caaacgtttg ggaatcattg acgcaaacga tacagaaggt cacgttttaa
    28921 ctggtgctga actcaatgaa ctgtcagatg aagaatttga aaaagtcgtt ggtcaatact
    28981 ctgtttatgc ccgtgtgtct ccagaacaca aggttcgtat cgtcaaggct tggcaaaaac
    29041 aaggtaaagt cgttgccatg acaggtgacg gtgtcaatga cgcgccagct ctgaaaacag
    29101 ccgatatcgg tatcggtatg ggaatcactg gtacagaggt ttctaagggg gcttctgata
    29161 tgattcttgc agatgataac tttgcgacta ttatcgtcgc agtggaagaa ggacgtaagg
    29221 tcttctcaaa cattcaaaag actattcagt acctactttc tgctaatact gctgaagtat
    29281 taaccatctt cctatcaacc ttgtttggtt gggatgtctt acagccggtt catcttttgt
    29341 ggattaactt ggtaacggat accttcccag ctatcgctct tggtgttgaa cctgcggaac
    29401 ctggtgtcat gaatcataaa ccacgtggac gcaaggcaag cttcttctca ggtggtgttt
    29461 tgagttctat catttatcaa ggtgtactcc aagcagctct tgttatgagt gtttatggcc
    29521 ttgcgattgc ttacccagtt catgtgggtg acaatcatgc tattcatgca gatgccctaa
    29581 cgatggcctt tgcaaccctt ggtttgattc agctcttcca tgcctacaat gtcaagtctg
    29641 tctaccaatc catcttgaca gttggcccat tcaagtctaa gacctttaac tggtccatct
    29701 tggtatcctt tatccttctc atggcaacaa tcgttgtaga accgcttgaa ggaatcttcc
    29761 acgtaaccaa actagacttg tcacaatggg gaattgttat ggctggaagc ttctcaatga
    29821 ttatcatcgt cgaaatcgtt aagtttattc aacgcaaact cggttttgac aagaatgcga
    29881 tttaagggag gtttcggatg tcagcatatc aattaccgac cgtatggcag gatgaagcta
    29941 gtaatcaagg agcttttacg gggctaaaca gaccaacagc aggtgcccgt ttcgaacaaa
    30001 acttgccaaa aggagaacaa gcttttcagc tttattcact gggaacacca aatggtgtga
    30061 aggttactat cttattggaa gaattactag aagctggttt taaggaagcg gcttacgact
    30121 tgtataagat tgctatcatg gatggggatc aattcggctc agactttgtg aagctcaatc
    30181 caaattccaa gattccagcc ttattggacc agtcaggtac tgaaaacgta agagtctttg
    30241 agtctgctca tattcttctt taccttgctg agaaatttgg agccttttta ccaagtaatc
    30301 ctgtggaaaa ggtagaagtt ttgaattggc tattctggca agcaggtgca gcaccttttc
    30361 taggtggggg atttggacat ttcttcaatt atgctcctga aaaattggaa tatcctatta
    30421 accgttttac gatggaagtg aaacgccagt tggatttatt ggataaggaa ttggctcaga
    30481 aaccttatat tgcaggcaat gactatacga ttgcagatat tgctatctgg tcttggtatg
    30541 gacagttagt tcaaggaaat ctttaccaag gttctgcaaa attcttggat gcctcaagtt
    30601 atcaaaatct agtaaaatgg gcagaaaaaa ttgccaatcg tccagctgtt aagcgtggct
    30661 tggaagtaac ttatacagaa attaaatagc aaaaaagtca tcttcggatg gctttttgct
    30721 acagttgagg gaaagggttt gcagttatcg gcttttgtgc tataattgct ataatatagt
    30781 aaaaagcaag aggagtgtga ggaagtggaa aagaaaattg tgaaggatat cttattttta
    30841 tctcaagtgt ctcatccggc aagtcaggag gacctttatc ttgccagaga tttgcaggat
    30901 acactcttag caaatcgtga tacctgtgtt ggtctagctg ccaatatgat tgggatgcag
    30961 aagcgcgtga ttatctttaa tcttggcttg gttcccgtgg tcatgtttaa cccagtgctt
    31021 ctgtcctttg aaggatccta tgaggcagaa gaaggctgtt tgtccttggt aggtgtgaga
    31081 tcaactaagc gttatgaaac cataaggctt gcctatcgtg acagcaagtg gcaggaacag
    31141 accattacct tgacaggctt cccagctcag atttgccagc atgagctgga tcacttggaa
    31201 ggacgaatca tttaggagga aagcaaatga aacgaatagt ctttgaactt atttttatcg
    31261 caacgacctg gtatatcttt ttaccgcccc ttaacctgac cagctgggaa tttctcttct
    31321 tcctctgtgg gcatttgtta gttgtggcaa tcttatttgg ctttggcaag gggataaacc
    31381 ttgtcaaaac ggttcatgtg cgccacggta aggcggaagc tgccttaaat cttgagggtt
    31441 tcaaaatcaa tcggttaggg aaaattctgt tagcttcgat tggaggaatt cttctcttgg
    31501 cagctttggt ttccttggta acttctagca tgtttcaggc taaaaattat gccaatgtag
    31561 tcacggttac ggaaaaagac tttactgaat ttcctaagag tgacaccagt aaggttccta
    31621 tcctagatag aagtactgct gaaaaaattg gagaccgcta cttgggttcc ctaaccgata
    31681 aggtgtcgca atacgtagcg gcagatacct atacccaatt gacaattgat gggaaacctt
    31741 atcgggtcac accactagaa tatgcagacc ctatcaaatg gtttaacaat caagccaagg
    31801 gaatcggtga gtatatcaag gtggacatgg taactggaaa tgcggatttg gtggacttga
    31861 agacaccaat caagtattca gactcggagt attttaaccg tgatgtcaaa cgtcacctgc
    31921 gcttgaagta cccgaccaaa atctttaaaa ctccatcttt tgaggtggac gatgagggca
    31981 atcctttcta tgtagcaacg gtttaccaaa agcaatttgg acttgctgtt cctcgtcctg
    32041 cttcagtcat tatcttggat gctacaaatg gagaaaccaa ggaatacagc ttatcagatg
    32101 ttccagaatg ggtggacagg atctatccag cagaggaaac cattgagcaa atcaactaca
    32161 acggcaagta caaggacggt ttcttgaatg ccatgatttc caagaaaaac gtgacccaga
    32221 cgaccaatgg ctataattac ttgtctatcg gtaatgacat ctatctctac acaggtgtga
    32281 cgtcggctaa tgcggatgag agtaatcttg gtttcatcct tgaaaatatg cgaacaggag
    32341 aaattactaa gtatagcttg gcttctgcga cagaagaatc agcccgtgaa tcagcagaag
    32401 gtgctgttca ggagaaatcc tacaaagcaa ccttcccaat cctcatcaac ctcaatgaca
    32461 agcctctcta catcatgggc ttaaaggaca atgctggctt ggtcaaagag tacgccctgg
    32521 tagacgcagt cgagtaccaa aatgttatcg ttgctactac agtggaagag atgctcagca
    32581 agtatgccaa taaaaacgac cttgaaattg acaatgcaac gacagaaagc atcaagggag
    32641 tagtagcaga cctcaaatca gctgttatca agggagacac tgtctacttc tttaaagttg
    32701 atggcaagat atacaaggta aaggcttcag tatccgatga ccttccttac cttgaaaatg
    32761 gtaaaacctt cgaaggtcaa gtaggaaaag acaattatct caagaccttt aaagtacaat
    32821 aatactcttc gaaaatctct agctctatct gcaacctcaa aacagtgttt tgagcagcct
    32881 gcggctagtt tcctagtttg ctctttgatt ttcattgagt ataaaaaagg tttatttaat
    32941 aaatatatgt tataataagg taaattaagc ctaatggagg acaaagaaat gggtttttat
    33001 ttgatggttg cttcaatgct actcggactg ctcgctttga agataggttt ttctcagttc
    33061 aaggagaaaa aagataaatt cttatctatc ttaacaagtt tagctggcac agcccttgtt
    33121 ctcgtggctg tctggttagg atggcccaaa taaatagaaa aacctcggtc aaaccgaggt
    33181 ttttcaaatg aatttcttgg ttgtggctaa aaaatatgct acactatcaa tatgaaaatt
    33241 ttaatcccaa cagcaaaaga aatgaacaca gacttgccaa gtatcgaggc aattccttta
    33301 aaaccagaaa gtcagaccgt gcttgatgcc ttggctctct attctgccag tcaattggag
    33361 agtttctaca aggtatcagc tgagaaagcg gcggaagaat ttcaaaatat ccaagctttg
    33421 aaaaggcaaa ctgctcaaca ctatccagcc ttgaaacttt ttgatgggct tatgtaccgc
    33481 aacattaaga gagataagct gaccgaggcg gaacaagatt atcttgaaaa tcatgtcttc
    33541 attacctcgg ctttgtacgg tgttgttcca gccttgtcac ccatggctcc tcaccgtttg
    33601 gattttttga tgaaattaaa agtcgctggt aagactttga agagccattg gaaggcagtc
    33661 tatgatgaag ctctgaagaa ggaagaagtg attttctctc tcttgtcatc agagtttgag
    33721 actgtatttt ctaaggaaat cagagcaaag atggtgacct tcaaattcat ggaggataga
    33781 ggcggtcagc tgaagattca ctcaactatc tccaagaaag cgcgcggggc ctttctaaca
    33841 gctttaatag aaaatcaagt acaaactgtg ggggaagcac gtcgcttgaa ctttgctgga
    33901 tttgtttacc gagaagattt gtcacaacca cagggattgg tttttgtaaa ggaagtatag
    33961 aaatcagata agagaaaagt cagcacgatt atgctgactt ttttgataac ttataaagta
    34021 ttggacaaat gaatctcatt tgataaggtg ttaagatgat taaccaaatt catgattgac
    34081 agatgatttc ggcaaataaa cttcttggta atccctgaaa tatagaaatt agacacgatg
    34141 atatcgtaat ctgtctgatt taaaatctca ggacttgttt ttaattcatc ccaaatatcg
    34201 aaggtaaagc ggttattaca gtaataggaa agcatatcaa caaaggtaag ggatatagca
    34261 tggtcaaagt tactgataat caaaaccttg ataggtggtc gattttctaa caactgagta
    34321 gagaggtttt cagcatgggt taagatggtg tacatcaagt gttccaactg ttcaggatgg
    34381 tcatgctgtc caattgcctg acggtattga gccagttctt gacgcgcact tcccataaag
    34441 tctgggaagt aaccttcaaa ttttttaatc gtcaatgctt tttgttcaaa taagattggg
    34501 gtagaaaaga tttcctgtct ttcaaagaaa gcagtgttgt gtaaatgcca aatcagctca
    34561 tcgtggttag taaaagtaat cttatattgt tttgataggc gttctaatat ttgactaagt
    34621 aattggtaag agtatcttgc ttgactgtta tcttctaaag agttgaagaa ttcttgagga
    34681 tctaggaaaa tatcattctg aagaaaagaa ataaaaattt gagcgattgt atctggagtc
    34741 atttcaagcc caaaatgttt agagaaataa gcaagtgtct cctggaaatt tggaatgctc
    34801 tttaaaagag gataatattc tttgtaaaag tggttgggga ggtcaatgaa gtgaccattt
    34861 ttaaccctgt ggatactgat agctatcatc agtttgtaca ttctataaat tgaaaatcgc
    34921 attggataat tcgtgatttt atagaagaag tcagcaaact ctgttaaatc ttcctcagga
    34981 aggtcaggaa aaggccaatc taggaaataa tagcgctcag aaaagtattg ggcaaaaaag
    35041 taacgaatat cgatctcatt tccacgtatc tcggatggag taaaagataa ttcaatttga
    35101 aactgagatg aaagaacctt tgtaatattt ctgcccagtc gatagaggtt ggcactacta
    35161 aagtaaagat tttctattgt tcgataaata ggtagcccct cattgaagaa catatactct
    35221 agtaattgaa aagattgaga attagcaaga aaatattgat aaatatcttc tacactagtg
    35281 ttaacttcta aatctatcat gattccgtta acagaagatt ggatgttaat agatggaaag
    35341 gcaatacgta attcatttaa atcacttttt aagattcgtt ctgtacatcc taatttttcg
    35401 gctagttcat gtaatttcat ccaattacga ttctgaatta gggtttccat taagcgtaat
    35461 tgtctttgaa cttttgtgga taaaaggttt ctcatacggg tatttcctcc ataattcatt
    35521 atatcttttt ttgtctaagt agtataaaaa aattagagca agaaaattgt cgttagtaat
    35581 cggaaaaatt agaataatat aagtggcttt taagtgcaaa aacagaatat attaattgtt
    35641 cagaaaatat tgattaatgc ctcaaatagt tgtacattgt aaactataaa atactatcta
    35701 ggagtttaaa atgaaacatt cacataaaaa atcatttgac tggtatagca tgcaacaacg
    35761 ttattctatt cgtaagtatt actttggtgc agttagtgtc ttgctcggta ccgctttggt
    35821 attaggtgca gcagctagtg tccaaacagt acaagcggaa gaaaacaaac aagaaactac
    35881 caatagtatt tctgttggta ggggagaagc agctactaaa ccagcagagg tttctgcgtc
    35941 taataaagag aaaacctatg cagctccaac tgtagctaat ccagtagaaa cgactccagt
    36001 taaaactgga gaagttacta aaccagcaga aaaagttgaa gaagcaaaag acaaaaaaga
    36061 ggaagtaacg catcaagatg ctattgacaa gtcaaaattg ttaacggctc tttcgcgtgc
    36121 taaaaagtta gaaagcaagt tatatacaga agcaagtgct gctaacttgc aaacaagtat
    36181 ccaagctggt caaagcttgc ttgggaaagc agatgcatct gaagctgaat tatcagcagc
    36241 agagtcatct attcaatcat ctattattgg tctagaactt cgttctaact ctaacaaagg
    36301 aactgtatca gaaactcctg tagcgaagaa agctaatata gttgaagcga aggaagagac
    36361 taatccagct gcaacaactg atcgttcagc tgttgatagt gctgttttgc caactagcac
    36421 agctgccaaa gtagaaacaa cttcagctcc agcatctatt aatgaaatct tgaaaccagg
    36481 tttgagcctt tctgatgctc gccaaaatcc agctatccgt aaggaagatg ttgatagagg
    36541 gtatagtggt tttagagcgg cgcctgctcc aacgaaccaa ccagtaacta atctaggaaa
    36601 taatactgtt ttcactgata ttagcagagg ttctcatact ttccgtggta atggaaattc
    36661 acgtcgtgga aacccgattc attttgatgt aacaacaact agagttagaa atagagtaga
    36721 tttctcaatc agatattcag gaccaggtga gtttgttaat aacaacttta tcttagacaa
    36781 aggaaatgga ttcggagaac cttctcgtgc aactgtttca acaccaaaat taagagacca
    36841 agttaaaaac attagtaagg gtggaaactt tgtttctcat tcaggctaca gtttagaagc
    36901 tgcagtagaa acaagcacca atcaaacaat taagtttagt ttacctatag ccaaccctaa
    36961 tggtgatctg tctgttcgat taagacctgt tacttttaat gtaggtcaag gggaatcagg
    37021 atctgcaact agtaatgatc catatagtaa ctctaactat tacttcagag aaaaaccact
    37081 cctcttggat gcaaatccaa atggtggtac taataataag actgtttcag aagacattga
    37141 cttccaaact gtctatcttc caactagtaa gttaccagaa ggtcaaacta gattagttcg
    37201 agaaggtgaa aaaggacaac gtcaaatcat ctataaagtt catcaattgg gtaacgaaac
    37261 aatcctagga ttgccaatta gtaattcagt tattaaagaa gttaagccac gtattatgca
    37321 aattggtgtg gctaaagatc taatcgatac agtaaaacca cgtgttgatc aaaataaagt
    37381 cggtgataca aataacctca ctttctatct tgataacgat ggaaacggtg tttatactga
    37441 gggcgtagac gaacttgttc aaaaaattgc tattaaagat ggtgctaaag gtgaaaaagg
    37501 agaccgaggc gaacgcggtc taactggagc tcaaggagct aaaggtgaaa aaggagaccg
    37561 aggtgaacgc ggtctaactg gagctcaagg agctaaaggt gaaaaaggag accgaggtga
    37621 acgcggtcta accggagctc aaggagctaa aggtgaaaaa ggagacc
//
LOCUS       DAVAZT010000016        37592 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVAZT010000016 DAVAZT010000000
VERSION     DAVAZT010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37592
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.016"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            51..299
                     /locus_tag="VQT45_000743"
     CDS             51..299
                     /locus_tag="VQT45_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359097.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRIYSGNLILQELITVNGAYKATYIGELSSN"
     gene            430..1602
                     /locus_tag="VQT45_000744"
     CDS             430..1602
                     /locus_tag="VQT45_000744"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HET2359098.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENADSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            1602..2876
                     /locus_tag="VQT45_000745"
     CDS             1602..2876
                     /locus_tag="VQT45_000745"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HET2359099.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLEFANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLIGILSNYATDSL
                     VTASCRMAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VAFSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(2912..3877)
                     /locus_tag="VQT45_000746"
     CDS             complement(2912..3877)
                     /locus_tag="VQT45_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2359100.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQTIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(3858..5312)
                     /locus_tag="VQT45_000747"
     CDS             complement(3858..5312)
                     /locus_tag="VQT45_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET2359101.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKSQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEHPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            5689..7572
                     /locus_tag="VQT45_000748"
     CDS             5689..7572
                     /locus_tag="VQT45_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET2359102.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYALADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVSKGDAVIE
                     VKI"
     gene            7721..8608
                     /locus_tag="VQT45_000749"
     CDS             7721..8608
                     /locus_tag="VQT45_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2359103.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGTSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(8928..9545)
                     /locus_tag="VQT45_000750"
     CDS             complement(8928..9545)
                     /locus_tag="VQT45_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HET2359104.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(9960..10148)
                     /locus_tag="VQT45_000751"
                     /pseudo
     CDS             complement(9960..10148)
                     /locus_tag="VQT45_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(10658..10738)
                     /locus_tag="VQT45_000752"
                     /pseudo
     CDS             complement(10658..10738)
                     /locus_tag="VQT45_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            10854..11747
                     /locus_tag="VQT45_000753"
     CDS             10854..11747
                     /locus_tag="VQT45_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2359105.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            11744..12943
                     /locus_tag="VQT45_000754"
     CDS             11744..12943
                     /locus_tag="VQT45_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2359106.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLEQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(13296..14063)
                     /locus_tag="VQT45_000755"
     CDS             complement(13296..14063)
                     /locus_tag="VQT45_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359107.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(14080..14775)
                     /locus_tag="VQT45_000756"
     CDS             complement(14080..14775)
                     /locus_tag="VQT45_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2359108.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(14780..15145)
                     /locus_tag="VQT45_000757"
     CDS             complement(14780..15145)
                     /locus_tag="VQT45_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2359109.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMIH
                     FGYEKEELPGVVSDYIKGV"
     gene            15285..15758
                     /gene="nrdR"
                     /locus_tag="VQT45_000758"
     CDS             15285..15758
                     /gene="nrdR"
                     /locus_tag="VQT45_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HET2359110.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            15759..16928
                     /locus_tag="VQT45_000759"
     CDS             15759..16928
                     /locus_tag="VQT45_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HET2359111.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFNPKEATIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRER
                     GQKTKTQKQNQTAPAKTNIPKWSNPDYKNETSEETRLELERKKQELLARLEKGGD"
     gene            16929..17825
                     /gene="dnaI"
                     /locus_tag="VQT45_000760"
     CDS             16929..17825
                     /gene="dnaI"
                     /locus_tag="VQT45_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HET2359112.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            17822..18535
                     /locus_tag="VQT45_000761"
     CDS             17822..18535
                     /locus_tag="VQT45_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HET2359113.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            18549..19859
                     /gene="der"
                     /locus_tag="VQT45_000762"
     CDS             18549..19859
                     /gene="der"
                     /locus_tag="VQT45_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HET2359114.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            19950..20285
                     /locus_tag="VQT45_000763"
     CDS             19950..20285
                     /locus_tag="VQT45_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359115.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            20425..20760
                     /locus_tag="VQT45_000764"
     CDS             20425..20760
                     /locus_tag="VQT45_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359116.1"
                     /translation="MEYLFKMIILLPCFYFFSWIEKANRDSKIFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            20945..21736
                     /locus_tag="VQT45_000765"
     CDS             20945..21736
                     /locus_tag="VQT45_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359117.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLEWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYVVPYMVLKKYEDNV"
     gene            21729..22370
                     /locus_tag="VQT45_000766"
     CDS             21729..22370
                     /locus_tag="VQT45_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359118.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLIVSRLEEKFKKG"
     gene            22374..23024
                     /locus_tag="VQT45_000767"
     CDS             22374..23024
                     /locus_tag="VQT45_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2359119.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            23035..23322
                     /locus_tag="VQT45_000768"
     CDS             23035..23322
                     /locus_tag="VQT45_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359120.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     MQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            23468..25981
                     /gene="secA"
                     /locus_tag="VQT45_000769"
     CDS             23468..25981
                     /gene="secA"
                     /locus_tag="VQT45_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HET2359121.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMATLTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQAMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            26062..27093
                     /locus_tag="VQT45_000770"
     CDS             26062..27093
                     /locus_tag="VQT45_000770"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET2359122.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            27095..28126
                     /locus_tag="VQT45_000771"
     CDS             27095..28126
                     /locus_tag="VQT45_000771"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET2359123.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            28165..28533
                     /locus_tag="VQT45_000772"
     CDS             28165..28533
                     /locus_tag="VQT45_000772"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HET2359124.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            28523..29626
                     /locus_tag="VQT45_000773"
     CDS             28523..29626
                     /locus_tag="VQT45_000773"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HET2359125.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLALPYDLIPALTLESALVHIKTVPAGACMGYGATYQTDSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            29645..31660
                     /gene="recG"
                     /locus_tag="VQT45_000774"
     CDS             29645..31660
                     /gene="recG"
                     /locus_tag="VQT45_000774"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HET2359126.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     IKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            31976..32956
                     /locus_tag="VQT45_000775"
     CDS             31976..32956
                     /locus_tag="VQT45_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HET2359127.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            33761..33988
                     /locus_tag="VQT45_000776"
     CDS             33761..33988
                     /locus_tag="VQT45_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359128.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            34276..37173
                     /gene="nanA"
                     /locus_tag="VQT45_000777"
     CDS             34276..37173
                     /gene="nanA"
                     /locus_tag="VQT45_000777"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HET2359129.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGNRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHNGKEYIILSNAGGPNRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT        11248 a         7005 c         8374 g        10965 t
ORIGIN      
        1 tactttcctt attgtctgta aatctactga ccttgttgtt tatcccagtc atggtttcta
       61 gttcgggctc agagtttcaa agtggatggc aagagcatca attgattgct gagaaggtta
      121 gtaaaacact tgataagaca tttgataagg atgtcagaga aattccgacc agtcagtttt
      181 atcaaaaatt tgtagatgag atgggaagga tttactcagg aaatttgatc ctccaggagc
      241 tgataactgt gaatggagct tataaagcta cttatatcgg tgaactctct agcaactaat
      301 cattctttaa aatgatgacc aataagaggc ttgatttggt gaatcaagtc ttttttctct
      361 cttttactgc catttgtgat aaaatagtat agaacgattt tttacatgaa tgataaaaca
      421 gaggtaaata tgacaatcgg tattgataag attggttttg cgaccagtca atatgtcttg
      481 aaattacaag acttagcaga agcgagggga attgaccctg aaaaattaag taaaggactc
      541 ttactcaagg aattgagtat tgcgccccta actgaggaca tcgtgacctt ggcggccagt
      601 gctagtgact ctattttaac tgagcaagaa agacaagaag ttgacatggt cattgtggct
      661 accgagtcag gaattgacca gagtaaggct gcggccgtct ttgtgcatgg cttgctgggc
      721 atccagccct ttgctcgtag tttcgagatt aaagaagcct gctatggggc gacagctgcc
      781 ctccattatg ccaaattgca tgtggaaaat tctccggagt ccaaggtctt ggtcattgcc
      841 agtgatattg ccaaatatgg tattgaaact ccgggagaac caactcaagg tgctggaagt
      901 gtagctatgt tgattacaca aaatccacgc atgatggcct ttaataatga caatgtagct
      961 cagacccgtg acatcatgga tttctggcga ccaaattact cgacaactcc ttatgtaaat
     1021 ggtgtctatt ctacccaaca atacttggat agtttgaaaa cgacttggct tgaatatcaa
     1081 aaacgctacc agcttactct ggatgatttt gcggctgttt gtttccactt gccttatcct
     1141 aaattagcgc taaaaggctt gaaaaaaatc atggataaga gcctgcctca agagaaaaaa
     1201 gacctcttac aaaagcattt tgaccagtct attctctaca gtcaaaaggt ggggaatatc
     1261 tacacaggtt cacttttcct tggacttttg tctctcttgg aaaatgcaga tagcttgaaa
     1321 gctggggata aaatcgccct ttatagttac ggaagtggag ctgtggctga gttcttcagt
     1381 ggtgaattgg ttgaaggata tgaagcttat ttggataaag accgcttgaa caagctcaac
     1441 caacgaactg ccttatccgt tgcagactat gaaaaggtct tttttgagga agtaaacttg
     1501 gatgaaacaa actctgccca gtttgctggc tatgaaaatc aagattttgc cttggttgaa
     1561 attctcgacc accaacgccg ttatagcaag gttgaaaaat aatgaagata agttggaatg
     1621 gattttctaa aaaatcatac caagagcgcc tcgagctgtt aaaagctcag gcgctcctta
     1681 gtcctgagag acaagctagt ctggagaagg atgaacagat gagtgtgact gtggcagacc
     1741 agctgagtga gaatgtagtg ggaacttttt ctctgcctta ttcgctggtt ccggaggtac
     1801 ttgtcaacgg tcaggaatac accgttccct atgtgacaga agaaccctct gtggttgcgg
     1861 cggccagcta tgccagcaaa atcatcaagc gtgcaggtgg ttttactgca caagtccatc
     1921 agcgccagat gattgggcag gtagcccttt atcaagttgc taatcctaaa ctagcgcaag
     1981 agaagattgc cagcaagaaa gcggagctct tggagtttgc caatcaagcc tatccttcta
     2041 tcgttaaacg tggaggtggg gcgcgtgatc tgcatgtcga gcagataaaa ggcgaaccag
     2101 actttctcgt tgtttatatt catgtcgata cccaggaagc catgggtgcc aatatgctca
     2161 acaccatgct ggaagccttg aaaccagtct tagaagaact cagtcaggga cagagtctca
     2221 taggaatcct gtccaactac gcgaccgatt ctctggtgac tgcaagctgt cgcatggcct
     2281 ttcgctactt gagccgccaa aaggatcaag gacgagagat tgcggagaaa attgcgttgg
     2341 ctagtcagtt tgcgcaggct gatccttacc gagctgctac tcataataaa ggaattttta
     2401 atggtattga tgcgattttg attgccactg gtaatgactg gcgtgccatc gaagctgggg
     2461 cccatgcctt tgccagtcga gatggacgct atcaaggtct tagttgctgg acgctggacc
     2521 ttgaaagaga agaattggtc ggtgagatga ccctgcccat gcctgtagcg actaagggtg
     2581 gctctatcgg cctcaaccca cgtgtagctt tcagtcatga tctactagga aatccttctg
     2641 ccagagaatt agcccagatt atcgtgtcca tcggtcttgc ccaaaatttt gcagccctca
     2701 aagctttggt aagtacgggc atccagcaag gccacatgaa actacaggcc aaatccctag
     2761 ctctcctagc tggggctagt gaatctgaag ttgctcccct agtagagcgc ctcatctcag
     2821 ataaaacctt taacctagag acagcccagc gctatctcga aaatttaaga tcataaaaaa
     2881 ctcagacgaa tcggtctgag ttttcttgtg tttaaatact ttttcctggt aatagtgtaa
     2941 ctggtaagaa gtaaccagtt gtggcaactt ccttgccttc aatcttttgc aagagaagat
     3001 caatagtgag acaagcaatc tcttccaaag gttgcttgat agtagccaat tgagggtagt
     3061 aattttcgat aaagtaggtc ccatcatagc cgatgacctt gagctctttt gggacagaaa
     3121 tgcccaattc ttgagcgatt ttaatgacca gaatagctgt caaatcatcc gaagcaaaaa
     3181 tggcatctgg tttttcccgg gtcaagatat tcttgatttc catttctttt ctgacgggag
     3241 aaaagtcact ggaaacattg ataataggag cttttgggag tacggatgca aaaccagcgt
     3301 ggcgtagtcc ggttggcgaa ttggaattgt cattccctgt aatcatgatg atagtctggg
     3361 cacctgtctt gaccaaggtt tgggcagcaa gaaccccacc agcatagttg tcagaggaga
     3421 cgacagggat gtctggcgat aggtttcggt caaaggaaat aatcggcgct gtcacacgat
     3481 tgtagtcttc gattcctagg ttgtgactac cagaaatgat gccgtccacc tgattggctt
     3541 ccaacatttc gatgtattcg cgttccttct cagaatcatg ttcactgttg cagatgatgg
     3601 tcttgtaacc atttttgaag agttggtgtt ccaatttatc aatcaattct gcatagaaaa
     3661 cattggaaat attagggaaa atcaagccga ttaacttagc tgattttcct tgcagactac
     3721 gagccaggtt gttgggttta tagcccaatt ctcgcatggc ttcattgact ttttggatgg
     3781 ttttctcaga tagataccct tttttattga taacccgaga aacggtagta ggactgacgc
     3841 ctgcaagttt ggcgacatca gttagttttg cgaccataat ctaattcata gtaagttcca
     3901 gttgggtttc cagatttgat caggatacca ttttggtccg catgtgggaa gacacgacca
     3961 gaaaatactt tttctccttt attgatgaaa atttcaaaga cagagttatc gatgaagatt
     4021 gtagcagtag tagcctgatt ctcgataggg caagaacgag ttgtcccaaa ttcttgggca
     4081 tactgttctc cagcctggct acgatccact gtcacttgac cgtttacaag gtcaaagttg
     4141 attgaaagtc ccttaccttc tttatcagca agtaagacaa tctcgctctg gctattagct
     4201 tccaagttga gttcaagttc gtaagtgttc ttggtttggg aacggtttga gaaggcttct
     4261 tcagaagcac gaaggtcctt aatagcagcg actggatact ggtagagctt gtcgtctttg
     4321 atagtgagtt ccttgaccaa agagaaggtt ccttggtggt caaaacggtc agatgggtaa
     4381 gaaacatctg gcaaaccaag ccagctaact gctagagcac gcccatcagg agcgttgaag
     4441 gcttgagttg cataggcttc gaaaccgtaa tccatgtttt gaagttgaga cacatctacc
     4501 attttggcat ttttagggtc aaaggaagcc ccaatcttat acatatttgg aaagatatta
     4561 tcgtagtcta gaactttctt atccaatcct tgtggacagt agagaaggac aggatgttcc
     4621 tctacaaaga ccagattagg acattccatc atgtaggcag tacggtcgtt agcaaagtca
     4681 aggtcgccaa ctgcttgcca gtttgtgtag tcgttattga cagccttgta gagacggacg
     4741 aagccttttt tctccaagtc ctgtccaccg acgacagcat agtattgact tttaaagtta
     4801 aaaatttgtg gatcgcggaa gtggtcagta gagtctgctg gctggtcaat caagatcttg
     4861 tcaatctttg taatcttacc ctccttgtcc atcaaagcac cgatctggta tgggtgacgg
     4921 atccagtttt catcgcgaac atttcctgta taaaatagga ataagttatc gccaaattgc
     4981 atggcagaac cagagtaggc accgtggcta tctaatggag tatctggtaa aactttgatt
     5041 ccagtttctt taaagtgaac caaatcatca ctttctagct gtgcccaaga tttcaaaccg
     5101 tgggctgcac caaaaggaaa attctggtaa aagaggatcc acttgccatc aaagtaagaa
     5161 aagccatttg ggtcgttgag aagtcctgtt tttggctcaa catggtaatg agtatgccat
     5221 ggagattgtg ccatattttc ctttatatgt tgaatttctt cttgcgtcca atcttgataa
     5281 agtctgtaac gacgctcagt tgtccattcc attcattcct ccaaaaatct tatcactttt
     5341 aatagtaact gttttcgata aaaaatgcaa gccttttatg ttaaaaaaga ggaaaaactg
     5401 tcaaacgatt atcataaaat aaatacagga aatcaatcaa atttttacga aaatgtgaaa
     5461 gataatgaaa taaaagactt tttaaccaag gtttcaaact tatttttcaa ggaattcctg
     5521 atgaaacagt caaaaacaat caatctaaaa cttgcccact aagtggatag aatatttttt
     5581 ctgcaaaacg cttgacatat ttttaaaaca tgataaaata atagtcgtaa gggcgaataa
     5641 aatcgctttc aaacaagaac aaaatgttat ataaggagat ttttgcaaat gaacaatcag
     5701 gaaattgcaa aaaaagtcat cgatgccttg ggcggacgtg aaaatgtcaa tagtgttgcc
     5761 cactgtgcga ctcgtctacg tgtcatggtc aaagatgaag agaaaatcaa taaagaagtg
     5821 attgagaact tggaaaaagt tcaaggtgct ttctttaact cagggcaata ccaaattatc
     5881 tttggtacag gtacagttaa caaaatgtac gatgaagttg ttgtacttgg cttaccaaca
     5941 tcatctaagg atgacatgaa agcagaagtt gctaaacaag ggaactggtt ccaacgtgct
     6001 atccgtactt tcggtgatgt tttcgttcca atcatcccag ttatcgtagc gacaggtctc
     6061 ttcatgggtg tgcgtggtct tttcaacgct cttgaaatgc cacttccagg tgactttgca
     6121 acttacacac aaatcttgac agatacagcc ttcatcatct tgccaggttt ggttgtgtgg
     6181 tcaaccttcc gtgtatttgg tggaaatcct gccgttggta tcgttcttgg tatgatgctt
     6241 gtctctggct cacttccaaa cgcttgggca gttgctcaag gtggtgaagt aacagcgatg
     6301 aacttctttg gtttcatccc tgttgttggt ttgcaaggtt ccgttcttcc agccttcatc
     6361 atcggggttg tcggagctaa atttgaaaaa gctgtccgca aggttgttcc agatgtcatt
     6421 gacctcttgg taacaccatt cgtgacactt ttggtcatgt ctatccttgg actctttgtc
     6481 attggaccag ttttccacgt tgttgaaaac tacatcctta ttgctacaaa agcgattctt
     6541 agcatgccat ttggtcttgg tggtttcttg attggtgggg ttcaccaatt gatcgtcgtg
     6601 tcaggtgtgc accacatctt caacttgctt gaagtgcaat tacttgctgc tgaccatgct
     6661 aacccattca acgctatcat cacagctgct atgacagctc aaggtgctgc tactgttgcg
     6721 gttggtgtta aaacaaaaaa tccaaaactg aaaacacttg ctttcccggc tgctctttct
     6781 gccttcctag gtattacaga gcctgctatc ttcggggtga acttgcgctt ccgtaaacca
     6841 ttcttccttt cattgattgc tggtgcaatc ggtggtggat tggcttctat ccttggactt
     6901 gctggtactg gtaatggtat caccatcatc cctggtacaa tgctttatgt tggtaacgga
     6961 caacttccac aataccttct tatggtagct gtatcatttg cccttggttt tgctcttact
     7021 tacatgtttg gttacgaaga tgaagtagac gcaactgcag ctgcaaaaca agctgaagtg
     7081 gctgaagaaa aagaagaagt tgcgccagca gctcttcaaa atgaaacact tgtaactcct
     7141 atcgtcggtg atgttgtcgc tcttgctgat gtcaatgacc cagtcttctc aagtggagct
     7201 atgggacaag gtatcgctgt gaaaccaagt caaggcgtgg tctatgcact agctgatgct
     7261 gaagtttcaa ttgcctttcc aacagggcac gcttttggtt tgaaaacaag aaatggtgct
     7321 gaagttttga ttcacgttgg tattgacact gtatctatga acggtgacgg ttttgaagca
     7381 aaagttgctc aaggtaataa ggtgaaagct ggcgatgttc ttggaacatt tgactcaaac
     7441 aaaatcgctg cagctggact tgatgataca acaatggtta tcgttacaaa tacagctgac
     7501 tacgcttcag tagctccagt cgcaacaggt tcagtttcga agggggatgc tgtgatcgaa
     7561 gtgaaaatct aatcaatcct ctctaatgtg aaaacgaaca aatgacatgt ttgttcgttt
     7621 ttattagata gtaagattta cagaggaaaa tctaaaaaat agagacattt agactttcga
     7681 agtatgctat aataaagaaa ataaaaacaa gaggtttatc atgacaaaat tatatggaag
     7741 cttggaagcg ggcggtacaa agtttgtctg tgctgtcggt gatgaaaact ttaacgttgt
     7801 agaaaaaaca caatttccaa caacaactcc aatcgaaaca atcgataaaa ccattgagtt
     7861 cttctcaaaa ttcgataacc ttgctggtct tgcagttggt tcatttgggc cgattgatat
     7921 tgacaaaaac tcaaaaactt atggctttat cacgacgact ccaaaaccaa actgggcaaa
     7981 tgtggacttg cttggtgccc ttcgtcgcgc cctaaacgtg ccaatgtact tcacaacaga
     8041 cgtaaacagc tctgcttacg gtgaaatggt tgctcgtaac aatgctggtg gtcgtatcga
     8101 aaacttggtt tactacacaa tcggtacagg tatcggtgca ggcgtcatcc aacgtggtga
     8161 gtttatcggt ggtgtgggtc accctgaaat gggtcattat tatgttgcta gacacccaat
     8221 ggatattgaa aaagagttta agggtgtttg tcctttccat aagggatgtc tagaaggtta
     8281 tgcagctggt acaagtttgg aagctcgtac aggtgtacgt ggggaaacta ttgaactcaa
     8341 caaccctgtt tgggatgttc aagcctacta tatcgctcaa gctgcggtta atgcgacagt
     8401 gactttccgc ccagacgtga ttgtctttgg tggaggggtc atggctcaac aacatatgct
     8461 ggaccgtgtc cgtgagaaat ttacatctct tcttaatggt tacctaccag taccagatgt
     8521 gcgtgactat atcgtgacgc cagcagtcgc aggaaatggt tctgccacac ttgggaactt
     8581 tgttcttgca aaagaagttt caaaataaag cacaaaatcc gcttgggaaa ccaaacggat
     8641 tttgtggttg aaaacaatat ttttgagcct ttccttaagt gattacggac ggtagcgact
     8701 ttcttcgaaa ttccatacct aaactttgag cctagtgtct caaagtttcc gaatacctga
     8761 aaccattaga tttcaggtgt ttctatcacg gcggaaaggc taggtaagtc ctcgcctcac
     8821 tatcgaaaaa tatgcataat ttccatacca aagtatattt agtatcaagc tatagttaat
     8881 ctacgcttta aaaatccact tgggaaacca aacggatttt ttacgtgtca aagcatttgc
     8941 cagaaaaagt caataatata ggtcagaccg taggtataaa ccacgagggt aaagggtttg
     9001 gtcagaatga tgatagtcat gtagcgcttg aaactcatct tggtcagggc ggccagcata
     9061 cagagaaagt cagctgggct aatgggccaa atcatcataa aaataaagaa gcggtcaaaa
     9121 cgattgccct tatctagcca gccgatgtac ttgtcgtagg tgcgcttgct gacgacagac
     9181 tggacaaagg cagctccgta taggcgcact agataaaaga taatggcaca gccaatcacg
     9241 atgccgatat agttgtagat agtcccgatg atgtgcccgt agataaagac cccagccacc
     9301 gaggtcaagg cccctggaat gatagggacg acagtctgta aaatctgtaa aaagataaag
     9361 agaggtggac cccagatgcc tgcctgctgg ataaaggcag agagggtttc cttggattgt
     9421 aaaatcccag cctgataagc ccaaatacag aaaatcaaac tcccaacccc accgacaatc
     9481 gatgagatat tgataactcg ctgcagaagg ggagaaacag ctttcatttg tttatcctgt
     9541 gacatgtaaa ctcctcatag atagtatatt tctactatac catattttgg aggagaaagg
     9601 gggaatgagt cttttttgat aaggaataga aagtaaatag cccttcgaga cttagaatag
     9661 gtctgtcaac taaaggttat atgcattcta ggtttcgaat aatcgcaatt ccataaattt
     9721 aaaagtattc taagtttcga atagcttatc tgagataatt ttgaggcatt cgcgctttcg
     9781 aatagtcatt ttccctaaag tttatatgta ttctgaagct agaaagacta aaatataaaa
     9841 gtagtaagag tctctctctg atggacgtaa tttatggcta gtatgaatcc tttgaattgt
     9901 tagttaattt taatattaat cagttctgaa ataattacta aatatagtta gatggtgagt
     9961 taattattgc taaatttcaa gttcaagtta gtcatccaga agtcttctct gggggacttg
    10021 tagttcaagc attttttagg atagttgtta atccactttt cgataaatgc gacttccttt
    10081 gtagttgttt tcttagttcc ctgaggtaac catctatgaa tgagcctgtt gtgattttca
    10141 ttagatccta tagtgatgtg cataatagat atagcagatt gaaactagaa tagtatacat
    10201 ctacttctaa aacattgtta gaaatcaatt tgactgtcct gatcaatttg tcctgttttt
    10261 atttcatttt actatataat ccttagaaaa catatcggac aagcggttga attccgttcc
    10321 gtccattagt agataaagga ttactccttc ttgaaatgac agatgaactt gtttcttata
    10381 aaaatgttgt ctgaaactat tagccttttt ccagaagttt tagaggaaga aaactttacg
    10441 aggaaaaagg agttactcaa ataacaattc aggattaaaa atagacagtt gaggagcgga
    10501 aggtataaat taagtttgct actgtataat ggatttatca ctaatactct tcgaaaatct
    10561 cttcaaacca cgtcagcttc gccttgccgt agatatagtt actgacttcg tcagttctat
    10621 ccacaacctc aaaacagtgt tttgagctga cttcgtcagt tttatctgca acctcaaagc
    10681 tgtactttga gcagcctacg gctagcttcc tagtttgctc tttgcttttc attgagtata
    10741 aaagtgctcc aggccatatt ttacacagca atagtcttct aaaaatggac aaaaacattg
    10801 taaaggctat caaaaaggag tataatgagt gcaagaaatt tcggaggtga aagatgctag
    10861 aagtaagaag tctagagaaa agttttggct ccaagcaagt tttgtttggt attgactttc
    10921 aagcgcgacc aggtcgtatt ttgggactag tcggaaaaaa tggtgctgga aaaacaacga
    10981 ttttccatag tattttgaaa ttcctagaat atcagggaga aatcggtctg gatggtcagg
    11041 atattcgtca ggagacctat gctcggattg gttatctgcc tgaagaacgc agtctcatgc
    11101 ctaaattgac agttcttgaa caagttcgct acttggcgac tctaaaaggc atggatgcca
    11161 aagaagtcaa agaaaaactc cctcaatgga tgaagaggtt ggaagtgaaa ggaaagctga
    11221 cagataaaat caagagtctg tcaaaaggaa atcagcagaa gattcagctc attattactc
    11281 tgattcatga accagacctg attatcttgg atgagccttt tagtggattg gacccagtta
    11341 atacagaatt gctcaaacaa gtcatttttc aggaaaaaga gcgcggagca accattatct
    11401 tttctgacca tgtcatgacc aatgttgagg aactttgtga cgatattctg atgatccgag
    11461 atggccgtgt ggtcttgcac ggaccagttc aggatgtccg caatcaatac gggaaaacgc
    11521 gtctctttgt ttcaagtgaa cgaagcaagg aagaattgga aaatcttcct catgtcaaac
    11581 aggtgagctt gaccaaacaa ggcagttgga aattgatttt ggaggatgag agcgctggaa
    11641 gggaactctt cccaatcttg actcaaggtc aatatatcgc aacatttgac caacaagcgc
    11701 caactatcga tgaaatcttt aaactagaat caggagtgga agtatgagaa atatgtgggt
    11761 tgtaatcaag gaaacctatc ttcgacatgt cgagtcatgg agtttcttct ttatggtgat
    11821 ttcgccgttc ctctttttag gaatctctgt aggaattggg catctccaag gttcttctat
    11881 ggctaaaaat aataaagtgg cagtagtgac aacagtgcca tctgtagcag aaggactgaa
    11941 gaatgtaaat ggtgttaact tcgactataa agacgaagca agtgccaaag aagcaattaa
    12001 agaagaaaaa ttaaaaggtt atttgaccat tgatcaagaa gatagtgttc taaaggcagt
    12061 ttatcatggc gaaacatcgc ttgaaaatgg aattaaattt gaggttacag gtacactcaa
    12121 tgaactgcaa aatcagctta atcgttcaac tgcttccttg tctcaagagc aggaaaaacg
    12181 cttagagcag acaattcaat tcacagaaaa gattgatgaa gccaaggaaa ataaaaagtt
    12241 tattcaaaca attgcagcag gtgccttagg attctttctt tatatgattc tgattaccta
    12301 tgcgggtgta acagctcagg aagttgccag tgaaaaaggc accaaaatta tggaagtcgt
    12361 tttttctagc ataagggcaa gtcactattt ctatgcgcgg atgatggctc tgtttctagt
    12421 gattttaacg catattggga tctatgttgt aggtggtctg gctgccgttt tgctctttaa
    12481 agatttgcca ttcttggctc agtctggtat tttggatcac ttgggagatg ctatctcact
    12541 gaataccttg ctctttattt tgatcagtct tttcatgtac gtagtcttgg cagcattcct
    12601 aggatctatg gtttctcgtc ctgaggactc agggaaagcc ttgtcgcctt tgatgatttt
    12661 gattatgggt ggtttttttg gagtgacagc tctaggtgca gctggtgaca atctcctctt
    12721 gaagattggt tcttatattc cctttatttc gaccttcttt atgccgtttc gaacgattaa
    12781 tggctatgcg gggggagcag aagcatggat ttcacttgct attacagtga tttttgcggt
    12841 ggtagcaaca ggatttatcg gacgcatgta tgctagtctc gttcttcaaa cggatgattt
    12901 agggatttgg aaaaccttta aacgtgcctt atcttataaa tagaagagcc ttgcgaaagc
    12961 gaggttttta aaggtgaaaa gggtggaatc acgaacctaa tgatgtacac attatgtaaa
    13021 caggttgctt gaaaactcaa ttgtatagtg aactgaatct ggaataggat aatattactt
    13081 ctaaaacatt cttataaatt gatttgaatt ccaaaatccc atcgttccgt tcttatttca
    13141 ttttgcgata tagtgaaagg aaataagtca gctcacaaaa aacgcataat atcaaggatt
    13201 tttaacactt gatactatgc gttttctaat tttaaagact ttttgcctgg tctcttttgt
    13261 tctatgagta tgttacatat ctaggtaaaa attatttaaa gcaaattaac cttatttctc
    13321 aagatgtagt aggttccgag ataaaagata gctatgaata tgagttcttt aacaatggct
    13381 atacctgctc ccatatagaa atggtcattg agtcctacca gtgaattgac atagaaatta
    13441 gaactaagat tgaagaaaag ttcaataaat ccaatgacga tttggatacc aatgtaggct
    13501 gcaacagcga gtgctgtacg gtattcattg aaaagctgtc caatggaaat agccaggtag
    13561 atgcagagga ttcctgaaat ggtatttagt aggaaggata tacctgtaag aaagatctga
    13621 gggagatgtg tttctacaaa tgtaatcaca taagaaagag gaatccattc tggagctgtt
    13681 aaagccagaa taataacagc acttagagcc aatacagcgg tgctaatcaa tgaccagata
    13741 aaggcaccga ttagtttggc tgtgatgata tggtgttcag aaactggcaa ggtcaaagtc
    13801 agatagcctt gtcggtcgta gacactacct ttgaagcgtt taataatcaa gaaaatggtt
    13861 gaaatcgcaa gtgtaagcat caagccacca aagactgtag ctagaaaaag tagcatagta
    13921 gcctgacttt cttggtaagg tagattttta aagccttgtg tctgtattcc gatgagggca
    13981 gaaaggacta gcacggctgc gtagagggct aaataccact tgttaacatt tttaaattcg
    14041 tagtgaacta aattccaaaa cataaataat ctcctttgct taggccttaa attcctgacg
    14101 gaagagttgg tcaatggatt cacctgactc gtagcgaata tcatctacat ttccttgacg
    14161 gacgactttt ccgtctttta ggaagacaat ttcatccaag attggctcga tatcagaaat
    14221 caagtgggta gaaatcaaaa cggtagaagt tggtgagtag ttgttgataa tggtattgag
    14281 gatataagca cgggctgctg gatccacccc accaatgggt tcatccaaaa catagagacg
    14341 agcatcacgg ctcataacca aaatcagttg aaccttttct ttgtttcctt ttgatagttt
    14401 cttgagacga ctattttcat caatgcccag gtctgcaagt agatgatgag cgcgttcaag
    14461 attgaaatct ttatagaagg tcttgaagta ggttagggct tctttgacct tcatttgctc
    14521 attgagatag gtcgtatcag gcaaataagc tacaacggcc ttggttgctg ggcttgggtc
    14581 catgtcgttg atgaggacac gtccttgatc tggttgtaag aggccattaa ttagtttaat
    14641 cagggttgtt tttcctgagc cgtttggccc aagaaggccg acaatttttc cagctggaat
    14701 gtcaagagaa acattttcaa gggctggtgt tgctccatat gatttggata cattttcaaa
    14761 tactagtaat gacataggct taaactcctt taatataatc actgactacg cctggtagtt
    14821 cttctttttc atagccaaaa tggatcatgg aggaaacgaa gtgttccaat tcttcttctg
    14881 ataattgttt gcgtgactga gcgattagct ccttatcctt agtcacaaat cgtccagttg
    14941 ttcgcttgct gtagacaaat ccttctcgtt caaggtctga taaggctctt tggatggtat
    15001 tgggattgac accagcctcg ctagctagct ccctcacggt tggaagttgt tgattgggtt
    15061 ccagtgtatg ggaaacaatc tgaagcttga ttttctccat aatctgtaaa tagatgggtt
    15121 ttttgttgtc aaatgtccag gacatcttag tctcctttct cttatccttt tgtcttaact
    15181 aaataataca acaaaacaaa aaacttgtca agcaaaaaga agaattgttt tgggaatcgc
    15241 ttaaaaaatg gtataatgaa aagaaaacga taaggaggga aaggatgcgt tgtccaaaat
    15301 gtggggctac caagtcaagt gttatcgata gtcgccaagc agaagaaggg aacaccattc
    15361 gtagaagacg tgagtgcgac gaatgccaac accgttttac aacctacgaa cgagtagaag
    15421 aaagaacctt agtggttgtt aaaaaagatg gtacacggga acaattctcc agagataaaa
    15481 tctttaatgg gattatccgc tcagcccaga aacgtcctgt gtcaagtgat gaaatcaaca
    15541 tggtagtcaa tcgtatcgaa cagaaactcc gtggtcgaaa tgaaaatgaa attcaaagtg
    15601 aggacattgg ttcactcgtc atggaggagt tggctgaatt ggacgagatt acctatgtac
    15661 gttttgctag tgtctatcgt agttttaagg atgtcagtga gttagagagc ttgctccaac
    15721 aaatcaccca gtcctctaaa aagaaaaagg aaagataaat gaagccaatt gaccgttttt
    15781 cttatctaaa gaataatcgg gtgtcgcaag atacctcatc tctggtacag tgctacctcc
    15841 cgattatcgg tcaggaggca ctgagccttt atctttatac aatcagtttt tgggataatg
    15901 gtagaaagga atatcttttt tcaagtatcc tcaatcatct caactttggg atggatagac
    15961 tgataaaatc attgaaaatc ttatctgctt ttaatctctt gaccctctat caaaaggggg
    16021 atgtttatca gctagccctc catgctcctc tatctagtca agacttcttg gagcatcctg
    16081 tttatcgcag actcttagag aaaaagattg gcgactctgc tgtggaggat ttgaaagttg
    16141 aaagtgctga tggtgaagaa atacctgtct cactcaatca agtctttcca gaattggcag
    16201 aactaggcag tcaagaagac cttggtctca agaagaaagt ggccaatgat tttgacttgg
    16261 aacattttcg ccagctgatg gctcgagatg gacttcgttt tgcggatgag cagtccgatg
    16321 tcttaaacct ctttgctatt gccgaggaga agaaatggac ttggtttgaa acctatcaat
    16381 tggccaagtc aacagctgtt tctcaggtta tttcaaccaa acgcatgcgt gaaaaaattg
    16441 ctcaaaaacc agtttcctct gactttaatc ctaaggaagc aaccattatc aaggaagcta
    16501 aaagtaagac tgccctgcag ttcttagcag aaatcaagca aacacgcaag gggaccatta
    16561 cccaaacaga aagagaactt ttgcaacaga tggctggctt gggcttgctg gacgaagtca
    16621 tcaatatcat tctcttgttg acctttaata aggtggattc ggcaaacatc aatgagaaat
    16681 atgccatgaa ggtggctaat gactatgcct atcaaaagat acattcagca gaagaggccg
    16741 ttttacgaat tcgtgagcga gggcagaaaa caaaaacaca aaaacagaat cagactgccc
    16801 cagcaaaaac caatattcct aaatggagta acccagatta taagaatgaa accagcgagg
    16861 aaactcgtct ggaactagaa cgtaagaaac aagaactatt agctcgatta gaaaaaggag
    16921 gagattagat ggaaagtgtc ggagacgtac tcaaacgtca acccagccgt ttttattatc
    16981 aagatttggt ccagaaaatc atgaaggacc ctgatgttgc ggcttttatc cagcaagaat
    17041 ccttgactcc agaggaatta aatcgcagta tctccaagtt taatcagtac atcaccgagc
    17101 gtgacaagtt tctccgtggg gatacggatt atattgccaa aggctacaag ccgattttgg
    17161 ttaagaatca tggctatgca gatgtttcat atgaagaaac tcctgagcta atcgcggctg
    17221 aaaaagaagc ggctattaag aatcgtctca agctaatcaa tctaccagcc agtctcaaaa
    17281 aagctagttt ggctcaagtt gatttggatg atttgggacg cttgccagtt tttgaaaaac
    17341 tattagcctt tgtggagcaa tatccagcta ttcgaaaagg tctttactta tatggagact
    17401 ttggtgtggg taaaagtttc atggtggcgg ccttagctca tgatttatca gaaaaacgtg
    17461 gtgtttcatc aactctcctc cactatccta gctttgtcat tgatgtcaaa aatgctatca
    17521 gtgatggcaa tgttaagacc ttggtggatg agattaagct gtctgaggtc ctgattttag
    17581 atgatattgg cgccgagcaa tcaaccgctt gggtgcgtga cgaaatcctg caggtcattc
    17641 tccaatatcg gatgcaggaa aatttaccga cctttttcac atccaacttc aactttgaag
    17701 atttggagaa gcattttgcg aaagtgaaac atggaaatga cgaaacctgg gaagccagac
    17761 gggtcatgga acgcatccgt tatttggctg aggagactcg tttagaagga gtaaaccgtc
    17821 gatgacagaa accattaaat tgatgaaggc tcatacttca gtgcgcaggt ttaaagagca
    17881 agaaattccc caagtagact taaatgagat tttgacagca gcccagatgg catcatcttg
    17941 gaagaatttc caatcctact ctgtgattgt ggtacgaagt caagagaaga aagatgcctt
    18001 gtatgaattg gtacctcaag aagccattcg ccagtctgct gttttccttc tctttgtcgg
    18061 agatttgaac cgagcagaaa agggagcccg acttcatacc gacaccttcc aaccccaagg
    18121 tgtggaaggt ctcttgatta gttcggtcga tgcagctctt gctggacaaa acgccttgtt
    18181 ggcagctgaa agcttgggct atggtggtgt gattatcggt ttggttcgat acaagtctga
    18241 agaagtggca gagctcttta acctacctga ctacacctat tctgtctttg ggatggcact
    18301 gggtgtgcca aatcaacatc atgatatgaa accgagactg ccactagaga atgttgtctt
    18361 tgaggaagaa taccaagaac agtcaactga ggcaatccaa gcttatgacc gtgttcaggc
    18421 tgactatgct ggggcgcgtg cgaccacaag ctggagtcag cgcctagcag aacagtttgg
    18481 tcaagctgaa ccaagctcaa ctagaaaaaa tcttgaacag aagaaattat tgtagaaagt
    18541 gagaaattat ggccctacca actattgcca ttgtaggacg tcccaatgtt gggaaatcaa
    18601 ccctatttaa tcggatcgct ggtgagcgaa tctccattgt agaagatgtc gaaggagtga
    18661 cacgtgaccg tatttatgca acgggtgagt ggctcaatcg ttcttttagc atgattgata
    18721 caggaggaat tgatgatgtc gatgctcctt tcatggaaca aatcaagcac caggcagaaa
    18781 ttgccatgga agaagcagat gttatcgtct ttgtcgtgtc cggtaaggaa ggaattaccg
    18841 atgcagacga atacgtagcc cgtaagcttt ataagaccca caaaccagtt atcctcgcag
    18901 tcaacaaggt ggacaaccct gagatgagaa atgatatcta tgatttctat gctctcggtt
    18961 tgggtgaacc attgcctatc tcatctgtcc atggaatcgg tacaggggat gtgctagatg
    19021 cgatcgtaga aaatcttcca aatgaatatg aggaagaaaa tccagatgtc attaagttta
    19081 gcttgattgg tcgtcctaac gttggaaaat caagcttgat caatgctatc ttgggagaag
    19141 accgtgttat tgctagtcct gttgctggaa caactcgtga tgccattgat acccacttta
    19201 cagatacaga tggtcaagag tttaccatga ttgatacggc tggtatgcgt aagtctggta
    19261 aggtttatga aaatactgag aaatactctg ttatgcgtgc catgcgtgct attgaccgtt
    19321 cagatgtggt cttgatggtc atcaatgcgg aagaaggcat tcgtgagtac gacaagcgta
    19381 tcgcaggatt tgcccatgaa gctggtaaag ggatgattat cgtggtcaac aagtgggata
    19441 cgcttgaaaa agataaccac actatgaaaa actgggaaga agatatccgt gagcagttcc
    19501 aatacctgcc ttacgcaccg attatctttg tatcagcttt aaccaagcaa cgtctccaca
    19561 aacttcctga gatgattaag caaatcagcg aaagtcaaaa tacacgtatt ccatcagctg
    19621 tcttgaacga tgtcatcatg gatgccattg ccatcaaccc aacaccgaca gacaaaggaa
    19681 aacgtctcaa gattttctat gcgacccaag tggcaaccaa accaccaacc tttgtcatct
    19741 ttgtcaatga agaagaactc atgcactttt cttacctgcg tttcttggaa aatcaaatcc
    19801 gcaaggcctt tgtttttgag ggaacaccga ttcatctcat cgcaagaaaa cgcaaataaa
    19861 aaagtagaat ctggaatgac agttccggat ttttttgata taataaaata atagaaaacg
    19921 ctatcaaaag aaggagggtg atgtcggtga tggaacattt gtttaaattc ttacttttag
    19981 caccgtactt ttattttgat aactggattg agaaggccaa cagaaatagt aagttttttc
    20041 caatttttta ttatttttac tggttttaca tccccttcta ttctcttttt agccttgctt
    20101 ggacagttgt ttcagttctg tttttcaata ccgtcttgag aaatgtgaca gatatcaagt
    20161 tatggggcat ttggtttctt tttattctgc tagctattgg tatgaattgg ttaacttatt
    20221 cctgtttcaa agaaatgttt cgcttgagac aggaactagg gaagtctaag ggtggaaggc
    20281 attgatttat atcggtttct atttgtagga ggtggcttat ggtacctcta aaatcattta
    20341 ttacacgcta ttccaaggtt tatattggta ataacattta atagaacgaa actaaagaaa
    20401 acaatttaaa agaggaggtt tgtgatggaa tacttgttta aaatgataat cttattaccc
    20461 tgtttttact ttttcagctg gattgaaaag gcaaacagag atagtaagat tttcccaatt
    20521 ttttactatt tttactggat ttacatcacc ctctatgctc tttttagcct tgcttggaca
    20581 gttttttcag ttctgttttt caatatcgtc ttgagaaatt tgacagatat caagttatgg
    20641 ggtatttggc tattattact acttatcgct tttgctagtg actggttaga ctatatctgt
    20701 ttcaaaaaaa tgcttgactt gagacgggaa ctagggaagt ctaaaggcgg aaggcattga
    20761 tttatactct tcgaaaatct cttcaaacca cgtcaacgtc gccttggatt atatatgtaa
    20821 ctgacttcgt cagtcttatc tacaacctca aagcagtgct ttgagcaact tgcggctagt
    20881 ttcctagttt gctctttgat tttcattgag tattatatta ctttctattt gtaggaggtg
    20941 gcttatgaag attcctctct taactttggc aaggcataaa tttgtttatg tcttgcttac
    21001 tttgcttttt cttgctttgg tttatcgtga tgttttgatg acttatttct tttttgatat
    21061 tcatgcgccc gatctagcta aattcgatgg acaagcaatt aaaaatgact tattaaaatc
    21121 agcattagat tttcgtattc tccagttcaa tctaggtttt tatcaatcat ttattattcc
    21181 aatcatcatt gttttgctag gttttcaata tattgagctg aaaaataaag ttttacgatt
    21241 gagtattgga agagaagtga gctatcaagg gttaaaaaga aagttgactt tgcaagttgc
    21301 aagtatccct tgtttgatat atttagtgac tgtgctgata attgcaatta taacctattt
    21361 ctttgggact ttttctcctc ttgaatggaa ttctctattt tctgatggga gtggtttaca
    21421 aagactccta gatggagaga taaaaagcta tttgttcttt acttgtgtcc tactaatcgg
    21481 tattttcatc aatgcaatct attttttaca aatagttgat tatgtgggga atgtgactcg
    21541 ttcggcaatc acctatttga tgtttctttg gcttggttct atgctgctct atagtgcctt
    21601 gccttactat atggttccta tgacgagttt gatgcaagct agctatgggg atgtaagttt
    21661 gatgaaactc tttactcctt atatccttta tgttgtccct tatatggtac ttaaaaaata
    21721 tgaagataat gtttaagaat tttaacaata tttggctaaa gagaaagatc gttttactac
    21781 ttcgtatagt tctgatgatg attttgataa actatctatt gtcaacagcg gttcaaaagc
    21841 aggatgctgt tatctttttc aagagagaat tgatttcaat tttttcctat aatgactatt
    21901 ctgaagcgaa tttagaaatc cccaaactct tgttaaacct ttcgcttttc atggtaggat
    21961 ggctctctgt cattttactt gaaagtgatt tggcagacca ttaccatcac ttgattcgct
    22021 atcaatcaag ctcctttttc gattatacaa ggaaacgatt ggttgtcatt tctaaatttt
    22081 ttactcaaga tttgtttgtc tggtttcttg gtttacttcc gctaggaatt catttcaaaa
    22141 cagtcgcact tttcttttta cttgctcagt taatgatgtt gtacttacta ctgtcttatc
    22201 tgatagcact gattagtgcg ggcgctggtt tttctttttt tctctatttt ttggcatttg
    22261 tgggacaaga atggatgatg gatcatattg taacagtgta tttagtactc ttaagcttat
    22321 tagttatgtt gattgttagt cgcttggaag agaaatttaa gaaaggataa acgatgagac
    22381 ttgaaattat aaatggacag aaaatttatg ggaaaagacc tattttaaat cagttgaatt
    22441 tggtgtttca atcaggaaaa atttatggac ttaaaggtga taatggatct ggcaagacgg
    22501 ttcttttaaa gatacttgct ggttatatta agcttgacaa aggaaaagtt cttcaagatg
    22561 gtaaagttta cggggtaaaa aatcattata ttcaggatgc aggaatttta attgaaaaag
    22621 tcgagttttt atctcattta tccctgagag aaaatttgga actgttaagg tatttttcat
    22681 ctaaagttac ggaaaaaaga attgcctatt ggattcaata ctatgattta caggaatttg
    22741 aagacgttga ataccgtcat ttatccttgg gaacaaagca aaaaatggcc ttgattcaag
    22801 cctttatttc ctctccttct atactctttc tcgatgaacc tatgaatgct ttggatgaga
    22861 agagtgtgag gttaaccaaa caggtcattt tatcttacct gaaaaaagaa aatggtctgg
    22921 ttatcctgac gtcgcacata tcggaagata tttcagacct ttgtacagat gtattagttg
    22981 tcgaaaatgg acatatacaa tatgtaaagg atatacaatc ctaggagatg gcttatggca
    23041 catctaaaat catttattac acgctattcc aaggtttata ttggtttagt tctgctgatc
    23101 tggctgtctt tcttctttat cccttgggat agagcgattc tgggggtaag gattgacatc
    23161 ttcatcatgc agaaaatctt gctagctttt ggaattctgt ccattctcat ggccttgctg
    23221 tccaagaaag tcagtctctt tgtttttgga ctgatttgct gtctttctct ttggattaac
    23281 ttatttatca catttgccat tttgccgatt tttggcaatt aaacagtcat aaaagtcgga
    23341 gaggttagct tgaaaactaa cctctttttc cttttcaaaa tggggattct tccttgaaaa
    23401 taatcagtaa ttgtgctaaa attaaaggaa cattctaaaa tattcggaat ttaaagtaag
    23461 gaaaaacatg gctaatattt taaaaacaat tatcgaaaat gataaaggag aaatccgtcg
    23521 tctggaaaag atggctgaca aggttttcaa atacgaagac caaatggcta ctttgactga
    23581 cgaccaacta aaagcaaaaa cagttgaatt taaggaacgt tatcaaaatg gagaatcact
    23641 ggattcattg ctttacgaag catttgcggt tgtccgtgaa ggtgccaaac gtgtcctagg
    23701 tctcttccct tataaggttc aggtcatggg ggggattgtt cttcaccatg gtgacgtgcc
    23761 agagatgcgt acaggggaag ggaaaacctt gactgcgacc atgccggtat acctcaatgc
    23821 cctttcaggt aaaggggttc acgtagttac ggttaatgaa tacctgtcag aacgtgacgc
    23881 gactgagatg ggtgaattgt actcttggct tggtttgtca gtagggatta acttggctac
    23941 caaatctcca atggagaaaa aagaagccta tgagtgtgat attacttact caactaactc
    24001 agaaatcgga tttgactacc ttcgtgacaa catggtcgtt cgcgccgaaa acatggtaca
    24061 acgtccgctt aactatgcct tggtcgatga ggttgactct atcttgattg acgaggctcg
    24121 tacacctttg attgtatcag gtgccaatgc ggttgaaacc agtcagttgt atcacatggc
    24181 agaccactat gtaaaatctt tgaacaaaga tgactacatc atcgatgtgc agtctaagac
    24241 tattggtttg tctgattcag ggattgacag ggctgaaagc tacttcaaac ttgaaaacct
    24301 ctatgacatc gaaaacgtgg ctttgactca ctttatcgat aacgcccttc gtgccaacta
    24361 catcatgctt ctcgatattg actatgtggt gagcgaagag caagaaatct tgattgtcga
    24421 ccaatttaca ggtcgtacca tggaaggtcg tcgttattct gatggattgc accaagctat
    24481 tgaagccaaa gaaggtgtgc caatccagga tgaaaccaag acatctgcct caatcacgta
    24541 ccaaaacctt ttccgtatgt acaagaaatt gtctggtatg acgggtacag gtaagactga
    24601 ggaagaagaa ttccgtgaaa tctacaacat tcgtgttatt ccaatcccaa caaaccgtcc
    24661 tgttcaacgt attgaccact cagaccttct ttatgcaagt atcgaatcta agtttaaagc
    24721 ggttgtcgaa gacgttaagg ctcgttacca aaagggtcaa cctgtcttgg ttggtacagt
    24781 agcggttgaa actagtgact acatttctaa gaaattggtt gcagctggtg ttcctcacga
    24841 agtcttgaat gccaaaaacc actatagaga agcccaaatc atcatgaatg ctggtcaacg
    24901 tggtgccgtt accatcgcaa ccaacatggc gggtcgtggt accgacatca agcttggtga
    24961 aggtgttcgt gaacttggag gactttgtgt tattggtaca gaacgtcatg aaagtcgtcg
    25021 tatcgataac cagcttcgtg gacgttcagg tcgtcaagga gatccaggtg agtcacaatt
    25081 ctacctatct cttgaagatg atttgatgaa acgttttggt tctgaacgct tgaagggaat
    25141 ctttgaacgt ttgaacatgt ctgaagaggc gattgagtct cgcatgttga cgcgtcaggt
    25201 tgaagcagct cagaaacgtg tcgaaggaaa taactacgat acccgtaaac aagtccttca
    25261 atacgatgat gtcatgcgtg aacaacgtga gattatctat gctcaacgtt acgatgtcat
    25321 cactgcagat cgtgacttgg cacctgaaat tcaggctatg atcaaacgca cgattgaacg
    25381 tgtcgttgat ggtcatgcgc gtgccaaaca agatgaaaaa ctagaggcaa ttttgaactt
    25441 tgctaagtac aacttgcttc ctgaagattc tattacgatg gaagacttgt caggcttgtc
    25501 tgataaggcc atcaaggaag agcttttcca acgtgccttg aaggtttacg atagtcaggt
    25561 ttcaaaacta cgcgatgaag aagcagttaa agaattccaa aaagttttga ttctacgagt
    25621 ggtggataac aagtggacag atcatatcga tgcccttgat caattgcgta acgcggttgg
    25681 acttcgtggc tatgctcaga acaaccctgt tgttgagtat caggcagaag gtttccgtat
    25741 gtttaatgat atgattggtt cgattgagtt tgatgtgaca cgcttgatga tgaaagcaca
    25801 aattcatgaa caagaaagac cacaggcaga acgtcatatc agtacaacag cgactcgcaa
    25861 tatcgctgct caccaagcaa gtatgccaga agatttggat ttgagccaga ttggacgcaa
    25921 tgaactttgc ccatgtggtt ctggtaagaa atttaaaaac tgtcacggta aaagacaata
    25981 aaatgagata gtttagaggc ggatatcttg tgaaaagtaa atttttactg ggtatccgtt
    26041 tgctttataa ggagatgagt tatggtattt acagcaaaaa gctctaaaat aaatatagaa
    26101 gaagttcgtg ccttgtcaaa attagaaggt caggctttgg agaggaaatc acagcgcgat
    26161 caagagctag aagccattat acgtggagaa gatcagcgaa ttctcttggt aatcgggcca
    26221 tgctcatctg acaacgaaga agctgtcctt gaatacgcta agcgtttggc agtcctacaa
    26281 gaagaagtgg cagatcgtat ctttatggtt atgcgtgttt atactgccaa accccgtacc
    26341 aacggagatg gctataaggg cttgattcac cagcctaacg cgacagaagc gcctagtctt
    26401 atcaatggaa tcaaagccgt tcgccatctt cactatcgtg tcatcacaga aacagggatg
    26461 acaactgctg atgaaatgct ttatcctgaa aaccttccgc ttgtagatga tttgatttct
    26521 tacatggcag ttggtgcccg ttcagttgaa gaccagcaac accgctttgt ggcaagtggg
    26581 gcaggatttt ctactggttt taaaaatcca acctctggaa atctcaatgt catgtttaat
    26641 gggatttatg ctgctcaaaa caaacaaagt ttccttttct taggaaaaga agtagaaaca
    26701 actgggaacc cgctttcaca cgctattctt cgtggtgctc ttaatgagta tggaaaaaat
    26761 attcccaact actattatga caatttaatt gataccattg cccaatatga gaaaatgggc
    26821 ttggaaaatc cttttatcat cattgatacc aatcatgaca attctggtaa gcagtatatt
    26881 gaacagatcc gaattgtccg ccagaccttg attaaccgtg cttggaatga aaaaattaag
    26941 cagttcgttc gtggttttat gattgagtct tatctggaag atggtcgaca aaatgagcca
    27001 gaagtatttg gcaagtctat cacagaccct tgcctgggtt gggataacac agaagctctt
    27061 gtcagagaaa tttacaaaac gttaggagaa taagatggca tttattgaaa aaggtcaaga
    27121 aatcgatatg gaagtcatca aggctgaaac ccaattgtct gcggaagcct tgagactcaa
    27181 ggaaagccgt gacagggaat tggcagatat tatttcaggg gaagatgacc gtattctctt
    27241 ggtgattggt ccttgctctt ctgataatga agaggcggtc ttggaatatg ctcgccgttt
    27301 atccgccttg caaaagaagg tagcggacaa gattttcatg gtcatgcgcg tgtatactgc
    27361 taagcctcgt accaatggag acggctataa aggattggtt caccagccag atacttctaa
    27421 ggctccaagc ctgattaacg gtttgcaggc tgtgcgccag ttgcattacc gcgtgattac
    27481 agagactggt ttgacaacgg cagatgagat gctttatccg tcaaatctga tcttggtgga
    27541 tgacttggtc agctaccatg ccgttggagc tcgttctgtg gaagaccaag agcaccgctt
    27601 tgtggcttct gggattgatg caccagtagg gatgaaaaat ccaacctcag gaaatttggg
    27661 tgttatgttt aacgccatct atgctgctca aaacaagcaa accttccttt atcatgggca
    27721 ggaagttgag acatcaggta atcctttggc ccatgttatc ctccgtggag cagtcaacga
    27781 gtatggcaat tatatgccga attactacta tgaaaaccta ctccaagcca ttgaacgcta
    27841 tgaaaccatg ggacttgaaa atccttttat cctcattgac accaaccatg ataactcagg
    27901 caagcaatat atggagcaga ttcgaattgt tcgccagacc ttgcagaatc gtgattggaa
    27961 tgagaaaatt aaaaagacgg ttcgaggatt tatgattgaa tcttacctag cagatggtcg
    28021 tcaaaaccaa ccagagatct ttggttgctc tattactgac ccttgcctag gttgggaaaa
    28081 tacagaggcc ttggtagaag agatttatgt taccttgaca aaataagtga aaaggatgga
    28141 gttggggaat ctcaactcct tttgatgaga atgatagttg gacacggaat tgacatcgaa
    28201 gaattggctt cgatagaaag cgcagttaca cgacatgaag gatttgctaa gcgtgtactg
    28261 accgctcagg aaatggagcg cttcaccagt ctcaaaggac gcaggcaaat agaatattta
    28321 gctggtcgct ggtcggctaa ggaggccttt tccaaggcta tgggaacggg cattagcaag
    28381 ctcggttttc aggatttgga agtattgaac aatgaacgtg gggcgcctta ttttagtcag
    28441 gcaccatttt caggaaagat ttggctgtct atcagccaca ccgatcagtt tgtgacagcc
    28501 agtgtcattt tggaggaaaa tcatgaaagc tagtccacat agaccaacca aggctctgat
    28561 tcatctggga gctattcgac aaaatattca gcaaatgggg gctcatatcc ctcaaggaac
    28621 gctcaagttg gctgtggtta aggccaatgc ttatggtcat ggagctgttg ccgttgccaa
    28681 ggcaattcaa gatgatgttg atggcttttg cgtttccaat atcgatgaag ccattgaact
    28741 cagacaagct ggactcagca agccaatcct cattttagga gtttctgaaa tcgaagctgt
    28801 tgctctagct aaagaatatg acttcacctt gacagtggct ggactggagt ggattcaagc
    28861 actcttagat aaggaagtgg acctaactgg attgacagtc cacctcaaga ttgattcagg
    28921 gatgggacgg attggtttta gagaggcaag tgaggttgag caggctcaag atttgctcca
    28981 acaacacggt gttcgtgttg aaggaatctt tacccacttt gctactgctg atgaggaatc
    29041 agatgactat tttaatgccc agttagaacg gtttaaaact attttagcta gtatgaagga
    29101 agttccagag ctggttcatg ctagcaattc tgcaacgact ctttggcatg tagagactat
    29161 tttcaatgcg gttcgtatgg gagatgccat gtatggtctc aatccaagtg gagcggtctt
    29221 ggctttgcct tatgatttga taccggcctt gaccttggag tctgctctgg ttcatatcaa
    29281 gacagttcca gctggtgctt gcatgggcta tggagcaact tatcaaacgg atagcgagca
    29341 agtcatcgcg accgtgccaa tcgggtatgc agatggatgg acaagagaca tgcaaaattt
    29401 ctctgtcttg gtagatggcc aagcttgccc aattgtcggc agggtttcga tggaccaaat
    29461 cactattcga ttgcctaagc cttacccact cggaaccaag gtaaccttga ttggctccaa
    29521 tggggataag gaaatcactg caactcaggt agcgacctac cgcgtaacca ttaactatga
    29581 ggtggtttgc ctcctcagcg accgtattcc gagagaatat tactagaaaa gaaaggagtg
    29641 gagcatgaat ctacatcaac ccttgcatgt cttgcctggt gtgggaccaa agtcagcaga
    29701 aaaatacgcc aaactaggaa ttgaaaactt gcaagatctc ttgctctact ttcctttccg
    29761 ttatgaagac ttcaaaatca agcaggtgct ggagctggaa gacggtgaga aggcagttct
    29821 ttctggtcag gtagtgactc ctgctagtgt ccagtattat ggtttcaagc gcaatcgcct
    29881 gcgttttagt ctcaagcagg gagaggtcgt ttttgcggtg aatttcttta accagcccta
    29941 tctggctgat aaaatagagt tgggagcaac ccttgctgtc tttggaaaat gggaccgcgc
    30001 taaggctagt ctgactggga tgaaggttct ggctcaggta gaagatgacc tccagcctgt
    30061 ctatcgtctg gctcagggaa tcagtcaggc cagtctggtt aaggtcatca agacggcttt
    30121 tgatcaggga ctggacctct tgatagaaga aaatctgccc cagtctttac tagacaaata
    30181 caaactcatg tcccgttgtc aggcagtccg agctatgcat tttccaaagg atttggcaga
    30241 atacaagcag gctcttcgcc gtatcaagtt tgaggaactc ttttatttcc aaatgcagct
    30301 gcagatgctc aagtctgaaa atagagttca gggaagtggt ctggttctga attggtctca
    30361 ggaaaaagtg acagcagtta aagtaagtct tccttttgcc ctgacccaag ctcaggaaaa
    30421 gagtttgcag gaaattttaa ctgatatgaa gtccgaccac cacatgaatc gtctcctaca
    30481 aggggatgtg gggagtggaa aaacggtagt cgctggcttg gccatgtttg cggcagtgac
    30541 agcaggttat caggctgccc taatggtacc aacagaaatc ctcgcagagc aacactttga
    30601 gagtttacag aacctttttc ccaatttgaa actggctctc ttgacaggtt ccttgaaagc
    30661 tgcagaaaag agagaggtct tggagaccat tgccaagggt gaggctgatt tgattatcgg
    30721 aactcacgct ctgatacaag atggggtgga gtatgctcgt cttggtttga ttattatcga
    30781 tgagcagcac cgttttggtg tagggcaaag gcgtatttta cgggaaaaag gtgacaatcc
    30841 agatgtcctc atgatgacgg cgactcccat tccacggacg cttgccatca cagcctttgg
    30901 agatatggat gtttccatta tcgaccagat gccagcaggt cggaagccta ttgtgacgcg
    30961 ctggatcaaa catgagcaac tacctcaggt cttgacttgg ttagaggggg aaattcaaaa
    31021 aggttcccaa gcctatgtca tctctccttt gattgaagaa tcagaagctc tagatttgaa
    31081 aaatgccatt gccttatcag aggagttgac gactcatttt gcaggcaagg cagaggtggc
    31141 tcttctacat ggtaggatga agagtgacga aaaagaccag atcatgcagg atttcaagga
    31201 gagaaagacg gatattctgg tttcgacgac ggttattgag gttggggtca acgttcccaa
    31261 tgcgactgtc atgattatca tggatgccga tcgcttcggt ctcagtcaac ttcaccagct
    31321 tagaggtcgt gtcggtcggg gggacaagca gtcctacgct gttctcgttg ccaatcccaa
    31381 gacggattct gggaaagacc gcatgcgtat catgacagaa acgaccaatg gatttgtcct
    31441 tgcggaggaa gatttgaaaa tgcgtggttc tggtgagatt tttggaacca gacagtcagg
    31501 acttccagag ttccaagtgg ctgatattat cgaagatttt ccgattttag aagaagcaag
    31561 aaaggttgct agctacatta gttctataga agcttggcaa gaagatccag agtggcgcat
    31621 gattgccctt catctggaaa agaaagaaca tctggattaa gctttctcta aggaaaactt
    31681 aagctagttt ttaggtttgg ctcttatact aaagtcatca aaaagaaacg aggactctca
    31741 tatgacagta acgattaaag taaattacca aaccactttc caaaagaagg aagcaaaaaa
    31801 ctagtataaa cagaagagag agcgaaatgc tctttttcgt ttctaaaact actttcagcc
    31861 catcatccta aaagtaaaga atctaaattc actttctatt tatccttctt tcttgcattg
    31921 attacataga tatgctacag ttgtggtaac gattacaaaa taaaaggagc atgctatgaa
    31981 aaatccagct ttgctagaag aaattaagac ctatagagga agggatgagg ttccggaaga
    32041 ctttgatgct ttctgggatg gggaagtgaa aaatgtttcc acgcttccat cctaccactt
    32101 ggaggaaaga gatttccaca ttcctcaagt caagtgctat gagttaacat ttgaaggaag
    32161 caaggaagga aaggtctatg cacgcattgt tcttccaaag agtgaggaga aggttccact
    32221 aatcttccat tttcatggtt atatgggacg tggctgggac tgggccgaca tgctgggctt
    32281 caccgtagct ggttacggtg ttgtttccat ggatgtgcgg ggccagtcag gttactcaca
    32341 agacggcttg cgttctcctt taggaaatac cgtgaagggg catattatcc gtggtgctat
    32401 ggaaggtcgg gaccacctct tttataagga tgtttatctg gatatttacc agttggtcga
    32461 aattgttgct agtctgtctc aggttgatga gaagcgtctt tctagctatg gtgcctcaca
    32521 aggaggggct ctagctctag ttgcagcagc gctcaatcct cgaattcaga aaacagttgc
    32581 catttatccc ttcttgtcag acttcagacg ggtgattgag attggtaata ctagcgaggc
    32641 ttacgacgaa cttttccgtt atttcaagtt tcacgacccc ttccatgaaa cagaggagga
    32701 aatcatggcg acccttgcct atatcgatgt caaaaatctt gcccatcgta tccaaggtga
    32761 ggttaagatg attacgggct tggacgacga tgtttgctat cccattaccc agtttgcgat
    32821 ttataatcgt ctgacctgcg ataaaaccta tcgcatcatg cctgagtatg ctcacgaagc
    32881 catgaatgta tttgtcaatg accaagtcta caactggctc tgtggaagtg agattccttt
    32941 taaatatcta aaataaggag tcgactctaa gcacaaaatc ttaaaaatta caaacacgca
    33001 tagtatcagg ggattaaaaa aacttgatac tatgcgtttt atcatggaaa tatagtaaaa
    33061 tgaaacaaga ataggacaaa acgatcagga cagtcaaatc gatttctaac aatgttttag
    33121 aagcaaatgt gtactattct agtttcaatc tattatattt atagaatttt ttgttgctag
    33181 atttgtcaaa ttgcttaaaa taattttttt cagaaagcaa aagccgatac ctatcgagta
    33241 gggtagttct tgctatcgtc aggcttgtct gtaggtgtta atacttttca aaaatctctt
    33301 taaaccacgt cagcttcgcc ttgccgtata tatgttactg acttcgtcag ttctatctgc
    33361 cacctcaaaa cggtgttttg agctgacttt gtcagtctta tctacaacct caaaacagtg
    33421 ttttgagcat catgcggcta gcttcttagt ttgctctttg attttcattg agtataaaaa
    33481 cagatgagtt tctgttttct ttttatggac tataaatgtt cagctgaaac tactttcaag
    33541 gacattatta tataaaagaa ttttttgaaa ctaaaatcta ctatattaca ctatattgaa
    33601 agcgttttaa aaatgaggta taataaattt actaacgctt ataaaaagtg atagaatcta
    33661 tctttatgta tatttaaaga tagattgctg taaaaatagt agtagctatg cgaaataaca
    33721 gatagagaga agggattgaa gcttagaaaa ggggaataat atgatattta aggcattcaa
    33781 gacaaaaaag cagagaaaaa gacaagttga actacttttg acagtttttt tcgacagttt
    33841 tctgattgat ttatttcttc acttatttgg gattgtcccc tttaagctgg ataagattct
    33901 gattgtgagc ttgattatat ttcccattat ttctacaagt atttatgctt atgaaaagct
    33961 atttgaaaaa gtgttcgata aggattgagc aggaagtatg gtataaatag cataagctga
    34021 tgtccatcat ttgcttataa agagatattt tagtttaatt gcagcggtgt cctggtagat
    34081 aaactagatt ggcaggagtc tgattggaga aaggagaggg gaaaattggc accaatttga
    34141 gatagtttgt ttagttcatt tttgtcattt aaatgaactg tagtaaaaga aagttaataa
    34201 aagacaaact aagtgcattt tctggagtaa atgtcttatt tcagaaatcg ggatatagat
    34261 atagagagga tcagtatgaa tcggagtgtt caagaacgta agtgtcgtta tagcattagg
    34321 aaactatcgg taggagcggt ttctatgatt gtaggagcag tggtatttgg aacgtctcct
    34381 gttttagctc aagaaggggc aagtgagcaa cctctggcaa atgaaactca actttcgggg
    34441 gagagctcaa ccctaactga tacagaaaag agccagcctt cttcagagac tgaactttct
    34501 ggcaataagc aagaacaaga aaggaaagat aagcaagaag aaaaaattcc aagagattac
    34561 tatgcacgag atttggaaaa tgtcgaaaca gtgatagaaa aagaagatgt tgaaaccaat
    34621 gcttcaaatg gtcagagagt tgatttatca agtgaactag ataaactaaa gaaacttgaa
    34681 aacgcaacag ttcacatgga gtttaagcca gatgccaagg ctccagcatt ctataatctc
    34741 ttttctgtgt caagtgctac taaaaaagat gagtacttca ctatggcagt ttacaataat
    34801 actgctactc tagaggggcg tggttcggat gggaaacagt tttacaataa ttacaacgat
    34861 gcacccttaa aagttaaacc aggtcagtgg aattctgtga ctttcacagt tgaaaaaccg
    34921 acagcagaat tgccaaatgg tcgagttcgc ctgtatgtta atggtgtttt atctcgaaca
    34981 agtctgaaat ctggcaattt cattaaagat atgccagatg taacgcatgt gcaaatcgga
    35041 gcaaccaagc gtgccaacaa tacggtttgg gggtcaaatc tacagattcg gaatctcact
    35101 gtgtataatc gtgctttaac accagaagag gtacaaaaac gtagtcaact ttttaaacgc
    35161 tcagatttag aaaaaaaact acctgaagga gcggctttaa cagagaaaac ggacatattc
    35221 gaaagcgggc gtaacggtaa accaaataaa gatggaatca agagttatcg tattccagca
    35281 cttctcaaga cagataaagg aactttgatc gcaggtgcag atgaacgccg tctccattcg
    35341 agtgactggg gtgatatcgg tatggtcatc agacgtagtg aagataatgg taaaacttgg
    35401 ggtaaccgag taaccattac caacttacgt gacaatccaa aagcttctga cccatcgatc
    35461 ggttcaccag tgaatatcga tatggtgttg gttcaagatc ctgaaaccaa acgaatcttt
    35521 tctatctatg acatgttccc agaagggaag ggaatctttg gaatgtcttc acaaaaagaa
    35581 gaagcctaca aaaaaatcga tggaaaaacc tatcaaatcc tctatcgtga aggagaaaag
    35641 ggagcttata ccattcgaga aaatggtact gtctatacac cagatggtaa ggcgacagac
    35701 tatcgcgttg ttgtagatcc tgttaaacca gcctatagcg acaagggtga tctatacaag
    35761 ggtaaccaat tactaggcaa tatctacttc acaacaaaca aaacttctcc atttagaatt
    35821 gccaaggata gctatctatg gatgtcctac agtgatgacg acgggaagac atggtcagcg
    35881 cctcaagata ttactccgat ggtcaaagcc gattggatga aattcttggg tgtaggtcct
    35941 ggaacaggaa ttgtacttcg gaatgggcct cacaagggac ggattttgat accggtttat
    36001 acgactaata atgtatctca cttaaatggc tcgcaatctt ctcgtgtcat ctattcagat
    36061 gatcatggaa aaacttggca tgctggagaa gcggtcaacg ataaccgtca ggtagacggt
    36121 caaaagatcc actcttctac gatgaacaat agacgtgcgc aaaatacaga atcaacggtg
    36181 gtacaactaa acaatggaga tgttaaactc tttatgcgtg gtttgactgg agatcttcag
    36241 gttgctacaa gtaaagacgg aggagtgact tgggagaagg atatcaaacg ttatccacag
    36301 gttaaagatg tctatgttca aatgtctgct atccatacga tgcataatgg aaaagaatac
    36361 attatcctca gcaatgcagg tggaccgaat cgtgaaaatg ggatggtcca cttggcacgt
    36421 gtcgaagaaa atggtgagtt gacttggctc aaacacaatc caattcaaaa aggagagttt
    36481 gcctataatt cgctccaaga attaggaaat ggggagtatg gcatcttgta tgaacatact
    36541 gaaaaaggac aaaatgccta taccctatca tttagaaaat ttaattggga atttttgagc
    36601 aaagatctga tttctcctac cgaagcgaaa gtgaagcgaa ctagagagat gggcaaagga
    36661 gagatgggca aaggagttat tggcttggag tttgactcag aagtattggt caacaaggct
    36721 ccaacccttc aattggcaaa tggtaaaaca gcgactttcc taacccagta tgatagcaaa
    36781 accttgttgt ttgcagtaga taaggaagat atcggacagg aaattattgg tatagctaaa
    36841 ggaagcatcg aaagtatgca taatcttcct gtaaatctag caggtgccag agttcctggc
    36901 ggagtaaatg gtagcaaagc agcggtgcat gaagttccag aatttacagg gggagttaat
    36961 ggtacagagc cagctgttca tgaaatcgca gagtataagg gatctgattc gcttgtaact
    37021 cttactacaa aagaagatta tacttacaaa gctcctcttg ctcagcaggc acttcctgaa
    37081 acaggaaaca aggagagtga cctcctagct tcactaggac taacagcttt cttccttggt
    37141 ctgtttacgc tagggaaaaa gagagaacaa taagagaaga attctaaaca tttgattttg
    37201 taaaaataga aggagatagc aggttttcaa gcctgctatc tttttttgat gacattcagg
    37261 ctgatacgaa atcataagag gtctgaaact actttcagag tagtctgttc tataaaatat
    37321 agtagattga aataagatgt gaacaactct atcaggaaag tcaaattaat ttatagaaaa
    37381 attttagcag tcaaggtgta ctgttataga ttcaatatat tatgtgacta ttaaccttct
    37441 cttctcctaa aattgacttt cttgttttct tatcttgtcc actcgaaaca agtattgtaa
    37501 gaatttgatt atttttgaaa gtacttttaa tatacttgat atagttaaaa aagatttgaa
    37561 actaaattcc aaattagaaa aagacttgaa at
//
LOCUS       DAVAZT010000017        37452 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVAZT010000017 DAVAZT010000000
VERSION     DAVAZT010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37452
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.017"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..777)
                     /locus_tag="VQT45_000778"
     CDS             complement(<1..777)
                     /locus_tag="VQT45_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2359130.1"
                     /translation="MSKETVVYTKRREKIKDNILGYSFLAPALILLGIFLVIPVGMVI
                     YYAFTDYYLLTPDERKFVGLENFIRLTKDPIFLKSFLNTLKFVVWIIPVQLGAALGMA
                     LIVNKKRKGNMFFKVAFFAPVVMSLVVISILWLYLLNPNSGLLNAILNKVGIASQPFL
                     TSPKQAMYAIVFVSAWQGAGYQMLLFLGGMQNIPQDVYEAAELDGFSKWAQFRYITMP
                     LLKPTALFVLLTTLISAFKLIVQPMVMTQGGPLNSTITMVY"
     gene            complement(873..2183)
                     /locus_tag="VQT45_000779"
     CDS             complement(873..2183)
                     /locus_tag="VQT45_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET2359131.1"
                     /translation="MRKGTMLSVVAGLSLAILAGCSGGTNSKQASSSNDIKVWVQFSD
                     ETNEGKAWQKVVDNFNQSGKSKYKVVTEYIPRSGSGGGYEDKVNAAITTNSLPDVITL
                     DGPNTAAYAKSKVITPLDDYLKDNNMDDVLDSIKQQGTYNGKFYAFGFSESNVGVYYN
                     KKMFKEAGIAESELPTLEKPWTWDEFNTIAKKLKDHYNKPAIDFRINSNDEMLPYAYM
                     PLIWSNNGSVVNEDGTKAEGYFNSKESVEAVQFIQNLVKEGYTTVSPVEKGFETGEYP
                     MLLSGSWTIADMNTNYKDIDFGILPYPVSSKTKKLVSPSGSWQLAVTTKSDKKEAASE
                     FVKFATNTESSEIISLGNSVLPIRKSTIENIKDKVSEPMRFLMEQNSKTAHARPVVVA
                     YPQVSRAFQQAMQDISYYEENPNVQKVLDTRTKEMQTAIDQSLK"
     gene            complement(2310..3305)
                     /locus_tag="VQT45_000780"
     CDS             complement(2310..3305)
                     /locus_tag="VQT45_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2359132.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLRKVQR
                     AIKTLDYIPDNYARGMKKNRTETIALIIPSIWHPFFSEFAYHVEKELLKYNYKLFICN
                     ADSDSQNEIEYIEMLKQNKVDGIIGITYSDIDKYILSDLPFVSIDRHFSENVCYVTSA
                     NYKGGQTAAEELVRRDNKHLAFIGSINMYENETILRSKGFREKAKELGVDVYNFEMKE
                     PLINPEDQIRIFLQSHKEIDGIFTINDMMALRVISVMKELGKIAPDDYQIIGFDGLKT
                     SVDQSYLVSTIVQDIGMMAKESVAMILKMIKREEILEKRIVIPTYFGGDKTTKKI"
     gene            complement(3667..5148)
                     /locus_tag="VQT45_000781"
     CDS             complement(3667..5148)
                     /locus_tag="VQT45_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2359133.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSS
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            5591..5755
                     /locus_tag="VQT45_000782"
     CDS             5591..5755
                     /locus_tag="VQT45_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET2359134.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            5839..6405
                     /gene="amaP"
                     /locus_tag="VQT45_000783"
     CDS             5839..6405
                     /gene="amaP"
                     /locus_tag="VQT45_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HET2359135.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            6417..6587
                     /locus_tag="VQT45_000784"
     CDS             6417..6587
                     /locus_tag="VQT45_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HET2359136.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            6626..7234
                     /locus_tag="VQT45_000785"
     CDS             6626..7234
                     /locus_tag="VQT45_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET2359137.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            7265..7468
                     /locus_tag="VQT45_000786"
     CDS             7265..7468
                     /locus_tag="VQT45_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET2359138.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(7578..7856)
                     /locus_tag="VQT45_000787"
                     /pseudo
     CDS             complement(7578..7856)
                     /locus_tag="VQT45_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895264.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            8054..8341
                     /locus_tag="VQT45_000788"
     CDS             8054..8341
                     /locus_tag="VQT45_000788"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET2359139.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCSRQRRLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(8619..9389)
                     /locus_tag="VQT45_000789"
     CDS             complement(8619..9389)
                     /locus_tag="VQT45_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HET2359140.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(9404..10252)
                     /locus_tag="VQT45_000790"
     CDS             complement(9404..10252)
                     /locus_tag="VQT45_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HET2359141.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDRFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(10249..11724)
                     /locus_tag="VQT45_000791"
     CDS             complement(10249..11724)
                     /locus_tag="VQT45_000791"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HET2359142.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYVSDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTSLKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(12047..13402)
                     /locus_tag="VQT45_000792"
     CDS             complement(12047..13402)
                     /locus_tag="VQT45_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2359143.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(13412..13729)
                     /locus_tag="VQT45_000793"
     CDS             complement(13412..13729)
                     /locus_tag="VQT45_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2359144.1"
                     /translation="MDESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(13746..14063)
                     /locus_tag="VQT45_000794"
     CDS             complement(13746..14063)
                     /locus_tag="VQT45_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2359145.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(14076..15761)
                     /locus_tag="VQT45_000795"
     CDS             complement(14076..15761)
                     /locus_tag="VQT45_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000791288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 16 glycosylhydrolase"
                     /protein_id="HET2359146.1"
                     /translation="MKNKKLISSLFILFLLIFIHVKVFANENLIKNSNFEQGELFWNS
                     RNRGIINSNESYSNGHYSGMIPSTAINDNRADGYIGQVIDIEPNEDYLVSAFAKVDIS
                     GAEGYFTARWFDNNKQGEIVQNNIGEAVDQTVNTTEWKKYMFSFNSGKHDKVLIQLVK
                     WSEDDTTKKSNIFIDNVEMYQLSKGNSYKKIWRDDFDGEQLNKKYWGYELGSIRGWEQ
                     QHYVRSDENVFLRSGNLVLRATNRSKEDQYFNPRNNHRKVVYNSGSVRTHGKVEFLYG
                     KLEMRAKLPKGQGVFPAFWTLGSDFTLDGKINPVQGRGWPSTGEIDIMELVGERNSNG
                     SGNKTVYQTLHYGQSDNDDGKFAGRGTAFKLSSGNFNDSYHTFSIDWYKDYIVWMVDN
                     HIVRKVYYGSDNIAKKIFNRPQYVQLNLAMGGSWPGVVDNNLSGTEFVVDYVSYSRND
                     LQQHQAEEYYSQSPKINGAKDIVINRGDVPDLLKGITTNSGYELDYSIENEPMFNNFG
                     GNTSVDLLIRNKTEKEKISQMPPGVYNLHYTSRPKHLDYESKVDRKTVTLTIK"
     gene            complement(15766..16662)
                     /locus_tag="VQT45_000796"
     CDS             complement(15766..16662)
                     /locus_tag="VQT45_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HET2359147.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(16665..17927)
                     /locus_tag="VQT45_000797"
     CDS             complement(16665..17927)
                     /locus_tag="VQT45_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2359148.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFITGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQGALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPSWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            18207..19385
                     /locus_tag="VQT45_000798"
     CDS             18207..19385
                     /locus_tag="VQT45_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET2359149.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(19613..20059)
                     /locus_tag="VQT45_000799"
     CDS             complement(19613..20059)
                     /locus_tag="VQT45_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2359150.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLPLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQDLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSGLKLE"
     gene            20129..20788
                     /locus_tag="VQT45_000800"
     CDS             20129..20788
                     /locus_tag="VQT45_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HET2359151.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCVIIFGKLLL
                     V"
     gene            complement(20840..21991)
                     /locus_tag="VQT45_000801"
     CDS             complement(20840..21991)
                     /locus_tag="VQT45_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET2359152.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(22006..22737)
                     /locus_tag="VQT45_000802"
     CDS             complement(22006..22737)
                     /locus_tag="VQT45_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359153.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            22966..23067
                     /locus_tag="VQT45_000803"
                     /pseudo
     CDS             22966..23067
                     /locus_tag="VQT45_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            complement(23039..23815)
                     /locus_tag="VQT45_000804"
     CDS             complement(23039..23815)
                     /locus_tag="VQT45_000804"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HET2359154.1"
                     /translation="MPKTLTKKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(23808..25031)
                     /gene="trpB"
                     /locus_tag="VQT45_000805"
     CDS             complement(23808..25031)
                     /gene="trpB"
                     /locus_tag="VQT45_000805"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HET2359155.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGFGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(25009..25608)
                     /locus_tag="VQT45_000806"
     CDS             complement(25009..25608)
                     /locus_tag="VQT45_000806"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HET2359156.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVAADLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            complement(25595..26362)
                     /gene="trpC"
                     /locus_tag="VQT45_000807"
     CDS             complement(25595..26362)
                     /gene="trpC"
                     /locus_tag="VQT45_000807"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HET2359157.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDC
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNTGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            complement(26359..27363)
                     /gene="trpD"
                     /locus_tag="VQT45_000808"
     CDS             complement(26359..27363)
                     /gene="trpD"
                     /locus_tag="VQT45_000808"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HET2359158.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEDYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(27374..27940)
                     /locus_tag="VQT45_000809"
     CDS             complement(27374..27940)
                     /locus_tag="VQT45_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HET2359159.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMICDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            complement(27937..29298)
                     /gene="trpE"
                     /locus_tag="VQT45_000810"
     CDS             complement(27937..29298)
                     /gene="trpE"
                     /locus_tag="VQT45_000810"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HET2359160.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQAIDRDPLDFLYEVTHKSQHHSDLPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRSVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            complement(29799..29876)
                     /locus_tag="VQT45_000811"
                     /pseudo
     CDS             complement(29799..29876)
                     /locus_tag="VQT45_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(30481..31482)
                     /locus_tag="VQT45_000812"
     CDS             complement(30481..31482)
                     /locus_tag="VQT45_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2359161.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            complement(31590..31958)
                     /locus_tag="VQT45_000813"
     CDS             complement(31590..31958)
                     /locus_tag="VQT45_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359162.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYGSFFSYEFICREVGN
                     ILKNKGVKCNLNFFEGEEYL"
     gene            complement(32054..32764)
                     /locus_tag="VQT45_000814"
     CDS             complement(32054..32764)
                     /locus_tag="VQT45_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HET2359163.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            complement(32767..34458)
                     /locus_tag="VQT45_000815"
     CDS             complement(32767..34458)
                     /locus_tag="VQT45_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET2359164.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDPNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            complement(34470..35480)
                     /locus_tag="VQT45_000816"
     CDS             complement(34470..35480)
                     /locus_tag="VQT45_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2359165.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            complement(35583..36650)
                     /locus_tag="VQT45_000817"
     CDS             complement(35583..36650)
                     /locus_tag="VQT45_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2359166.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            complement(36675..37334)
                     /locus_tag="VQT45_000818"
     CDS             complement(36675..37334)
                     /locus_tag="VQT45_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HET2359167.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
BASE COUNT        12046 a         7633 c         5730 g        12043 t
ORIGIN      
        1 gtacaccata gtaattgttg agtttaatgg gccaccttgc gtcataacca ttggttgtac
       61 aatcagctta aaagcagaaa ttaaagttgt taacaataca aacagggctg ttggttttag
      121 taggggcatc gtgatataac gaaactgagc ccattttgag aatccatcta attcagcagc
      181 ttcatagaca tcttgtggaa tattctgcat tcctcctaaa aataaaagca tctgataacc
      241 tgcaccctgc caagcagaaa caaaaacaat tgcatacata gcttgtttag gactagtcaa
      301 gaaaggttga gaagcaatac ctaccttatt taaaatagca tttaataagc cactatttgg
      361 atttaaaaga taaagccaaa gaatagaaat aactaccaag gacatgacaa ctggagcaaa
      421 aaaagccact ttaaaaaaca tatttccttt tcgcttttta ttgacaatca aagccattcc
      481 taaggccgct cccaattgaa ctggaataat ccaaacaaca aatttcaaag tattcaagaa
      541 gctctttaag aaaatcggat cttttgttaa tcgaataaaa ttttcaagtc caacaaattt
      601 tctttcatct ggtgtcaaca aataataatc tgtaaaagcg taataaatga ccattccaac
      661 tggaattact aaaaagatac ctaataaaat taaagctgga gctaaaaaac tataacctaa
      721 tatgttatcc tttatttttt cacgtctttt tgtatacaca acagtttctt tactcatatc
      781 catctccttt aatcatatat atcaaactag gctattaaca agaaagggga aggtagttcc
      841 aaacattttc cttccacctt cttttttaca gattatttga gtgactgatc aatagcagtt
      901 tgcatttctt ttgtacgagt atccaagact ttttgcacat ttggattttc ttcataatag
      961 ctaatatctt gcattgcttg ttgaaaagct cgagaaacct gaggatatgc tacgacaact
     1021 gggcgagcat gagctgtttt tgaattttgt tccatcaaga aacgcattgg ttcggatact
     1081 ttatctttga tattttcaat tgtagattta cgaattggaa ggaccgaatt ccccaagcta
     1141 ataatttcac ttgattctgt atttgtagca aatttaacaa attcagatgc ggcctctttt
     1201 ttatcagatt ttgtcgtcac agctaattgc caactacctg aaggggatac taattttttc
     1261 gtcttactag atactgggta aggaaggata ccaaaatcaa tatctttgta gtttgtattc
     1321 atgtcagcaa tcgtccaaga accactcaaa agcattggat actctcctgt ttcaaaacct
     1381 ttttcgactg gactaacagt tgtatagcct tcttttacaa gattttgaat gaattgaact
     1441 gcttctacac tctctttgga gttgaagtat ccttctgcct ttgttccatc ttcgtttacg
     1501 acagaaccat tatttgacca aatcaacggc atataagcat atggcaacat ttcatcgttt
     1561 gaattaatac gaaaatcaat tgctggtttg ttataatgat ctttcaattt tttagcaatc
     1621 gtattaaatt cgtcccatgt ccatggcttt tctagcgttg gaagctctga ttccgcaatt
     1681 ccagcctctt tgaacatttt tttattgtaa taaacaccaa cattcgattc agaaaatcca
     1741 aatgcataga atttcccatt ataagttccc tgttgtttaa tactgtccaa aacatcatcc
     1801 atattattat cttttagata atcatctagc ggagtaatta ctttagattt tgcataagct
     1861 gccgtatttg gtccatcaag ggtaataaca tctggaagac tattagtcgt aatagcagca
     1921 ttaaccttgt cttcatatcc tccaccacta ccactacgag gaatatactc agttacaacc
     1981 ttgtacttac tttttcctga ttgattaaag ttatcaacaa ctttttgcca agcttttcct
     2041 tcatttgttt cgtcagagaa ttgtacccag actttaatat catttgaaga actcgcttgt
     2101 tttgagttag ttcctccact acaacctgca agtatagcta acgatagccc cgcaacaaca
     2161 gataacattg tacctttacg catcattttt ctcctttttg aaacgtttca ttttttattt
     2221 attttttaaa caagcttcta gcctattttt gaaacgtttc atttgttgat tatattataa
     2281 cagcgctttc attaattgtc aagcgctttt taaatttttt ttgttgtttt atctccccca
     2341 aaatatgtgg gaattacgat tcgtttttct agaatctctt ctcgcttaat cattttcagt
     2401 atcattgcaa cagattcttt tgccatcata ccaatatctt gaactattgt agacactaga
     2461 taagattgat cgacagaagt ttttaaacca tcaaacccaa ttatctggta atcatcaggt
     2521 gctattttcc ccagttcttt cataacacta ataactctca gagccatcat atcatttatt
     2581 gtaaatatac catcaatttc tttatgagat tgcaaaaaaa ttcttatctg atcttcagga
     2641 tttattaaag gttctttcat ttcaaaatta tagacatcta ctcctaattc cttagctttt
     2701 tctctgaatc ctttacttct gagtatagtc tcattctcat acatattaat tgaaccaata
     2761 aaagcaaggt gcttattatc ccttctaacc agttcctctg ctgcagtttg tcctcctttg
     2821 taatttgctg aagtaacata gcatacattt tccgaaaaat gtctatctat acttacaaac
     2881 ggtaaatcag ataaaatata tttgtcaata tcagaatatg taataccaat aattccatcc
     2941 actttatttt gtttcaacat ttcgatatat tcgatttcat tttgtgaatc gctatcagcg
     3001 ttacaaataa ataatttata attatatttt aataactctt tctcaacatg ataggcaaac
     3061 tccgaaaaaa atggatgcca tatgctcgga ataatcaaag cgatagtttc tgttctattc
     3121 tttttcatac ctcgagcata attatcaggg atatagtcca atgtttttat agccctttga
     3181 actttcctta aagttacttc tttaatgcct ttttctttat taattacacg tgaaacagtt
     3241 ccaacactaa ctcctgcttc taaagcaaca tctttcatgg taattgattt tctttgttct
     3301 accatattat cacctccttt caatatatag tatcatgcaa atgcttttta agcaactatt
     3361 tctcaatcat ttttggccag atcatttatc ccatcatgaa taaaatcact ccaattagct
     3421 tttgaaaata cttcaatttt catgtgtaaa catctacata aaacaggaaa agccttggtt
     3481 ttatggcttt tttcgtatct tctacaaaaa aagcaagagt tttagagggc tataaatcta
     3541 gatgtacatt ttgcttaaat gattgaaggt cttttcttaa caaaaacacc ccaaaaatta
     3601 gattttttct gtctaacttt tgaggtacag ttcaaacgcg aaatagcgtt tttttgttat
     3661 ttttggttac tcatctaatc gaataaacat catggcattt aacaaatata tgagtgagac
     3721 cgtgtttata ttatttgaat agatgagtct cttattttca ataggaggaa taataaaatt
     3781 agaaataatg atatcataag atgaatcttc taaagattcc tttgataatt ctaattcagt
     3841 ccaaacttcc agttcaaaat tattgctaca gtaataagaa agtgtctctg caacgaattt
     3901 tgcatgatac tgatcaaaat tactcataac caaaaccttt agtttaggct gattttgtag
     3961 caaattaatc accaaatgtt tggtatgagt gatgaaggta taagatagat gatttaccat
     4021 cattgaacta gaacaaacct caagagtctc taaatagtga gaaagctctt tttttatatc
     4081 tgaaacaaat tttggaaaaa tattttgaaa gttcctgatt gtattccctt tttgatcaaa
     4141 taaaataaac tcagtaaaca actcttgacg atacagatgt gcggtattat gcagatgcca
     4201 aatcagatta tccttattct ccatttcaat ctgatacttg actgaaatct gatcaataaa
     4261 atcactcaat agatggtaag atttttcaac ataactatcc ttttttacgc atttcataaa
     4321 gagactttca tctatgaaaa acattttttg aaagtaagac acaaataatt ggcaaacaac
     4381 ttcttcatct aaagagatat tgtattctga ttcaaaactc tgagcaacac cttctattcc
     4441 ttctgcctgc attaaaaaat ccaaactttg gtcgttaaaa gaatctttat ctacttccat
     4501 aaaatgacca aactttattc tatataggtt cgtaactagg agcaacttta gcattctatg
     4561 cgttgacaaa ttcattggaa agcttgtttc cttataaacc aattctaaca attgagatag
     4621 tggctctgat gaaaaatttt caaatggcca ttctaggaaa taatattttt ctgaaaaata
     4681 ttgtgcaaaa aagtaacgaa tgtctctctc atttccaatg atttgaacag gggtcagact
     4741 gacttcaaat tgaaattgcc ttttaatcac tttattgatt tggctaataa tacgatagag
     4801 cgaagatgaa ctgatataaa attctttaca aatactctca gcttgacaac cttcattaaa
     4861 gaagatgaat tctaaaatcg aaaaatgagt tgaatgttta aagaaatgat ggtaaaccat
     4921 ttcaatatca ctatcatcgg tattaataat gcgtatacca ttagtagaag aatgaaaaat
     4981 caagtcagga aaagcagatt taacatggga tagatcatct ttgactgcac gttctgtaca
     5041 atttaataac tctgctagtt cagaacgatg aaaccaacgt ttatgttcaa ataataattc
     5101 taataattct aattgcctat gacttttttt agataataaa tctctcatga atatctttct
     5161 ctctttataa attatcggat taaacctctt gcaattatac cacaaagaat aggtatagca
     5221 tgatataacg acttttccta aaatctttta tttcgtataa taacactacg gagacaatat
     5281 ataaacaatt ttcttatttt accgtctatt gagggcgtga atacagaatc aaattcaagt
     5341 ctaaagatta tatttttaat tttaaaaatt atataatagc aacaattaaa gaatttgatt
     5401 ttttaaaatt atataataat aacaatcgaa ataattgact tttctatatt aaagttatat
     5461 aatagtatta atcaaagaaa ttgatttttt gatattaaaa taaaaaagga gggtaggcag
     5521 tgttgtgatc aattattgct ggaggtctta ttggtctctt ggcaggtaaa atcactaaaa
     5581 aagtagttct atgggaatca tcgcaaatgt attcgctggt ttagtcgggg catatgcagg
     5641 acaatctctt ttaggtagtt ggggtccatc aatcgctgga atggctttgc tcccatctat
     5701 tgtaggtgca gcgattgtga ttactgtagt gtcattcttt acaggtagaa agtaaacttt
     5761 tcgccagtaa agttagcaaa ctatttttaa atcaatgacg ggaaaaatag tttaaatgtt
     5821 aaatcgaaag gattgtatat gtcaaaagca aagaaaatat gtttcattat tttctgtatt
     5881 ttaatcttga caattttcct tcctgttttg atagattatc atcaagttag tgatctaggt
     5941 attcatctac ttagctggag acagaactcc gtagttgaat tctatcttgc tagatatgtc
     6001 ttttggggga cagtggttct atcaacttta gttttattat ccattttagt tgtgatgttt
     6061 tatcctaaac gttacttgga aatccaactt gaaactaaaa acgatacatt aaaattaaag
     6121 aattcggcaa tcgaaggttt tgttagaagt ttggtgagtg atcatagatt gatcaagaac
     6181 ccaactgttc atgtaaattt acgaaaaaat aaatgtttcg ttcatgtaga aggtaaaatt
     6241 cttccttcag acaacatcgc tgacagatgc caaataattc aaaatgaaat aactaatgga
     6301 ttgaagcagt tttttggtat tgagcgtcaa gtaaaacttg aagttgcagt aaaaaattac
     6361 caaccaaaac ctcaaaacaa aaagactgtt agtcgtgtga agtaaggaag taaaaaatgg
     6421 aatggcttaa acaatatcga tatccaatta tcgctggtct cataggcgta tttctggctt
     6481 gtttgattgt ctcctttggc ttcttcaaaa caatatttgt attgatttta ggagcactgg
     6541 gagttgcagc tggattatat atcgaaaaaa actatataga taaataaaaa aataaaaatt
     6601 actaatttaa ttaaaggagt ttcatatgtc aaacgaaaaa aacacaaata ctaacgtaga
     6661 aaagaaagat gctactgttg tagctcacga aatcaaaggg gaacttactt acgaagataa
     6721 agttatccaa aaaatcattg gtctttcact agaaaacgtt tcaggtcttt tgggaatcga
     6781 tggtggtttc ttctcaaatc ttaaagaaaa aatcgttaac agcgatgacg taacaagtgg
     6841 tgttaacgta gaagttggta aaacacaagt tgcagttgac ttaaacgtta ttgttgagta
     6901 ccaaaaaaat gttccagctt tatattcaga aatcagagaa atcgtatctt cagaagttgc
     6961 taaaatgact gacttggaaa ttgttgaaat caacgtaaac gttgtcgaca tcaaaactaa
     7021 agaacagcat gaagcagact cagtaagcct tcaagatcgc gtatctgacg ttgctgaatc
     7081 aacaggagaa ttcacttcag aacaattcga aaaagctaaa tctggtcttg gatctggttt
     7141 ctcaactgtt caagaaaaag ttagcgaagg tgtagaagct gttaaaggtg cagcaaatgg
     7201 tgtagtatct cacgaaaaca ctcgtgtaaa ctaagataaa ataaatataa caggagaaat
     7261 tatcatgtca gtagaagaaa aattaaatca agctaaaggt tctattaaag aaggtgttgg
     7321 gaaagccatc ggtgatgaaa aaatggaaaa agaaggagca gctgaaaaag ttgtttctaa
     7381 agtaaaagaa gttgccgaag acgctaaaga cgctgtagaa ggtgctgtag aaggtgttaa
     7441 aaacatgttg agtggcgatg ataaataagg ttaaaagtta ctttatcttt ttggtaacat
     7501 tagtcaaaag agtctgagtc aagatgattc tcagaaaaca aaaagctaga gattcccaat
     7561 tgcggaactc tagcttttta attttgcctc tttctcttat tatatttcag caggttgttg
     7621 gccatgagta tgaatcccat gtcaattctc acttgacgct tacctctcag atgacatctc
     7681 ttataaccca aacaaacctt tatctgccca aagacagatt tcatatcaat cttacgttta
     7741 gcgaaaattt gtctaccctt ggaagataaa agtgcctgat attctttagt ttttaaacac
     7801 tggtaacgtt cattcatata cagtcccttt tgaggggctg attcaggttc ataatcgcag
     7861 tcaacattga tttcaaggct gtttgctttc tatctcccct ttttcatgat atattttcgt
     7921 acaggttctt caatagtttc tatagtaaaa tgaaccaaaa atagtacacg ttgcggtata
     7981 atgttcttgt ggcatattca ttagattttc gtaaacagtt ctctcctatt tgtgagcgaa
     8041 caagtatagt caattgattg tcagtttgaa gaccaagagt cgtaaggcaa aggatatggc
     8101 agaatccatc caagggtggc tggcacaatt tctagtgaac ctctttaaat ctattacgtt
     8161 tgactgtgga aaagagtttt caaaatggaa agatatttcc aatcatcacg atagtgagag
     8221 cttttttgcg aatctaggat gttcaagaca gcggcgtctc aacgaacatt caaatagact
     8281 tttaaggtgt catgacttgc caaagcagac agatttcaac gaagtcagtc aagaatttta
     8341 ggctggacaa aaactcaatt tcaggagaaa atgaaataaa tattcccaca ataaaacgca
     8401 tagtatcaaa gtttttccaa cacctgatat tatgcatttt ttaattttaa agactttttc
     8461 ccagcctcaa gaaatcacat cccacctaaa tcctttggat accaaatacc tcatcaggta
     8521 ttttctgagt tggtaagaat gtctagctta atttgacaaa tggagggcgt taaatccagt
     8581 ttttacagga agtctattta aatattttca cactgacctt acaaaatatg aaataaatta
     8641 tataaagtca ttcccatgac aaagaataac atccctttaa aacagtatct tacccaattt
     8701 tcaggtaaga cttttgatac aaccgtcccc aatacccctc cgcatataga agcaagaaaa
     8761 ataactggaa caggtgctaa atgatactga tttaaacctg taaccacaac aattgtagcc
     8821 aaatgagaca gctgggaaaa gaaaataatt gcaagagaat acatcgttgc ttcttttatc
     8881 gaaatagaaa aaaacaccat caataaagat acattgagcg gaccaccacc aatccctaaa
     8941 aaactagaaa ttaagcccaa tagaagacca caaatcatat agaatcctat cttatcaaat
     9001 tgataagttt ttttaaaatc tgttaaaaca aatgatacaa gtagcatcac aaatagtaaa
     9061 atcatttgaa caatggatac tagccgtact gataactgag ataacaaaac ttgaaaaata
     9121 agatgaccta gaaatcctcc taaaacagaa gaaaaggata ccgtaaaaat caatctccat
     9181 tttatctctt tactttgtga aaatcttttg attgttgaaa taatcgccat tataaaaaca
     9241 gagaaactag aataaaaagc aatatcactg accgaatggt atccaaaact atccataagt
     9301 ggcttaatta taattccacc acccatgcct gatatagaac ccaatccact agctattata
     9361 atgattagaa aataaataat ctcaaccact ttttaagtcc atcctattct ttcaaacatc
     9421 taaaacctag atggctacta gtggaagtag agatacatcc atttctagca gctactcggt
     9481 atcgattaca ataagaacaa tgacataaaa aggaacctcc tctgatagca tactcctcat
     9541 cttgtatccc atattttggc aactcatagt catcttcatt aaaactagct aataaggtat
     9601 atctcggatt gcgacaccat tcccaaacat tcccaatcat ttgatataga ccaaaatcat
     9661 taggtaaaaa ttcatagaca ggagccgttc ctataaatct atctaaggca gtattttcat
     9721 aaggaaatct tccttgccaa gtattggcat gataatatcc accttctaaa agagtatctc
     9781 cccaaggata ttcagattgt cttcctcctc tagcagcata ttcccactgt gcttcagtag
     9841 gtaaagacat tccgctccaa ttacagaaag ccaatgcatc ttctaaagca acatgaacta
     9901 ctggatggtc ttctaaaccc actagattac tgttctcacc gtagggatgt ttccagcaag
     9961 cgttcggaac ttgtaaccac cacggagccc cagcaggatg aggatatccc tccctttctg
    10021 cctctggaac gaacaatata aaaacaaaag accactcttg tcgctcagct agtgttttat
    10081 agcctgtttc tttcacaaat tgagcaaatt cttgattcgt aactggagta tccgcaatgg
    10141 aaaaatcctt tacactaaca gcgacttgag gaccttcaaa atcatctaaa aagccctctt
    10201 cagaatttgt tcccatcata aatgtcccac ccttgatttt tttcattttc atgattgact
    10261 atcccccgtt ttcgttagag ttggcgttat tttagaaagt tcaacaggaa ctaactcttc
    10321 atccacaaca aaaccttctt ctctatatct aagaaagtct actaattttt tcttcatctg
    10381 acgaacaata ggttggtatt tttcgcttgg atacaaatca ttcatttcat gcggatcttt
    10441 tttcatatca aataactgat aatgatttaa aacaggaaac cagataaatt tccactggtc
    10501 tgtcaagata tattgactag aatcttttcc taaagcatgt tcaccatgaa attctgttcg
    10561 ccacccctcg tactgtccaa ataataaatt cttaacactc cgtccatcta gttcatctgt
    10621 agtagttcct cctgccaaat ccacgagtga aggaaaaata tcttgaattt tcactaattg
    10681 cttgattgtt cccctattac cagctatcaa tccagccgga tcgtaaataa acgaaggaat
    10741 gtggatactt ccctgataag gatatccctt tctaaacaga taatgttcac caagctgatc
    10801 tccatgatcc gaaacaaacc agataatcgt atctttatca tgacgaaatt cttttaggga
    10861 agtcaaaaag cgactaattt gatggtctat atgagtaatc aatccaaaat aagcagcaac
    10921 cattcttctt tgatcatctt cctttaattt ccctcttaaa gcataaatag acggaatttg
    10981 cttttctaat acttcccaat tcccgatatg caaatcgaga aattgaggca agcgttccat
    11041 atacatatca aaatagtatt ttgggggatt taatggagca tgtggttttt caaaagacat
    11101 tttgagaaaa aaaggaaccg ttggatctct tctttgtaaa aatgaaatgg actcactcac
    11161 aacccagttt gttggatgta acttctcatc tttatcccaa ggtctagctt cccaagaatt
    11221 acaatccatt ccgtcatcaa tcaaatcaac atcataacca actttaccct ttaaaaaggc
    11281 tagatagtca ctaacataat caaattgact tccataagcc ttatcatact ttctatcaac
    11341 atgtagatac ccatcgtgaa gtaagacatg atcaaaccca agtctctgtc tggaaggaaa
    11401 aacatgcatc ttaccaatac actctgtttg ataacccata tctttaaaga cttttggaag
    11461 agtattagta aaattccaag gcacctcatc ttgataacca acacgtccac ttttatcttg
    11521 gtctaagcca gtcaataaag ctgccctagc aggaacgcaa gaaggaactg gagaataggc
    11581 attttcaaaa ttataaccta cactagccat catatctaat gttggagtgc taactagctt
    11641 atccttacta ttcaaggata aggcgtctgc tctcatttga tctacaacaa tcaaaataat
    11701 atttggctgt tttgtctgaa ccataaaatc tcctttctaa tatggcaaaa gaggcacaag
    11761 aagatatcta cctttactgc acccctttct atatcaatct ctctatataa agcaataaca
    11821 ttcttgttat gttttataga acaatgaact aaaatatgac taaatcgatt aggaaattca
    11881 aatcattttc tagtactgtt ttagaagtta cagtgtacta ttccaacttc aacaaactat
    11941 aaaccttggt ctaataacaa ttttagtgga gataagaaat cctacaccta actcatctta
    12001 cacgtaatct atttctattt tatcacaaaa aacgcaagta agaccattaa ctcaattcag
    12061 ttttatctgc cattttcaca aatgggaaat aagtcaagac actaataatc aaacaaacaa
    12121 ctgataagat gatggcacgc caatcaaatg ctgtagagaa gaaaccatat aaaattggag
    12181 gcattaccca agtaacattt tgtgtaacag gtgaaacaag accccagctt gttgcccagt
    12241 aagctaccgt tgccatgaaa accgggctaa gtacaaatgg tataaatagc aaaggattca
    12301 agacaactgg taaaccataa ttgaccggct caccaatatt aaacagaact ggtgctagac
    12361 caagtttagc aacttttcga taatgactgt ttcttgaaaa aattaaaata gcaagtacca
    12421 atcctaatcc tccaaaccag acaaacgccc caaaagaccc acttgtccat atataaggaa
    12481 tcggttcacc tttttggaaa gcatccagat tcgctaacat agcaactcca aacagccctt
    12541 ccatgatggg agccaataca tttcctccat ggagaccaaa aaaccagaat aacttattta
    12601 aaaagatcat cagaataact gcaaagaaac tttgagacaa acctagtaat ggcgtttgta
    12661 acaccttgta aacccaatca atcaataagt cattgctaag taaatggaaa acataagtca
    12721 agatggctac tatatacatc gccataaatc ctggaatgat agaagtgaac ggcttagcaa
    12781 tcgcaggggg aactgaatct ggtaacttga ttacccagtt ctttttcatt actttacaga
    12841 aaataataga ggctaaaaat ccaatcatca tggctgtaaa gtagcctctg gcattaatat
    12901 ggtttcctgg aatcacattc ccaatagtta ccatcagatt tttaccatca aatgctagat
    12961 tatcaattcc ttgtaagatc tgatctaatt tcacatctcc tacatttgcc aaagggaaac
    13021 tctttgtaac tgtacttcca atcgaaatga caaacgaagc aagtgatacc aaaccagcag
    13081 aaactgtatc aaccttgtaa atcttagcga tattcactcc caagcaatag atgaacaaca
    13141 aagaaacaat tggtatactt cccttgaata ccaaattatt gatgtcaaca agccactgaa
    13201 aggttttcgt aatactttct aggtgaaatt gttgtggtaa atccactaga aaagcattta
    13261 ataacaaagc aatggaacct gtcataataa caggcatagt ccccacaaat gaatcacgta
    13321 aagcaactaa aaacttctga ttcccaactt tcattgcaat tggagaaagt ttttcttgca
    13381 ttttatccaa cattgtattc atactaaact cctaattttt ttcaaatcgt tcgtatactt
    13441 ctaccacttc tttcgccaag tcaacaaaag tcagactcgt cattaaatga tcttgcgcgt
    13501 gtaccatcaa gaggctaatt gatgtttctt ccccctgtgc ctctcttgtc aacatttctg
    13561 tttgagcctt atgcgcctgt aataaggcag cattcgcatc agctaatctt cgattggctt
    13621 tagagaaatc cccttttttt gctgcctgaa tagcctccat agcattactt ttggcttccc
    13681 caccatacat aattagcccc attacagatt ctaaattact ttcatccata acattctcct
    13741 caatcttagt ctaataaact ttcagctaaa tctaaaactt tagaaccatt catcattccg
    13801 taatctgtca tcggaataac cgccacagga atctgtctat cttttagttt ttcttgaaag
    13861 tcccctagta aatagcgaac ttgggggcct aaaagcaaca catttacttc ttttgttgct
    13921 acaatttctt ctgcttcagg agctggaact gcaaaaattt ctgcatccaa ccccttatct
    13981 tctgctgcct tttgcatctt tgtcactagc agacttgtac tcatacctgc tgcacacgct
    14041 aacataattg ttactttagc catagcttac tccttttatt ttattgtcaa tgttactgtt
    14101 tttcgatcaa ctttagactc ataatctaaa tgtttgggac gactagtata atgcaaatta
    14161 taaactcctg gaggcatttg tgaaatcttt tctttttcag ttttattgcg aattaataaa
    14221 tctaccgaag tattccctcc aaagttatta aacataggtt cattttcaat agaataatct
    14281 aactcatatc cactattagt tgtaattcct tttaataaat caggaacatc tcctctgttt
    14341 attactatat ccttagcgcc atttattttg ggagattgac tataatactc ttcagcttga
    14401 tgttgttgta aatcatttct agagtaagaa acataatcaa ctacaaattc agtccctgat
    14461 aaattattgt ccactacccc aggccaactt cctcccatcg ctaaatttaa ctgaacatac
    14521 tgaggtctat taaaaatctt tttcgctata ttatctgatc cataatatac ttttctaaca
    14581 atatgattgt caaccatcca tacaatataa tctttatacc aatcaattga aaaagtatga
    14641 tacgaatcat taaagtttcc actcgataat ttaaaggctg taccacgtcc tgcaaatttt
    14701 ccatcatcat tatccgactg tccataatga agcgtttgat aaactgtctt attcccactt
    14761 ccatttgaat ttcgttcacc aactaattcc attatatcta tctcacctgt tgacggccat
    14821 cctcgtccct gaacaggatt aatcttccca tcaagtgtaa aatccgatcc aagagtccag
    14881 aaagcaggaa aaactccttg acctttcggt aattttgcac gcatctctaa tttaccataa
    14941 agaaattcta ctttcccatg tgttctaaca cttcctgaat tatatacaac ctttctgtga
    15001 ttgtttcttg ggttaaaata ctgatcttcc ttagagcgat tcgtagctct aagaactaaa
    15061 tttcccgaac gtagaaaaac attctcatca cttcttacat aatgttgctg ttcccaacca
    15121 cgaattgatc ctaattcata tccccaatat tttttattta attgttcgcc atcaaaatca
    15181 tctctccaaa ttttcttata tgaatttcct ttagacagtt gatacatctc tacattatca
    15241 ataaaaatat tagatttttt tgtagtatcg tcttctgacc atttcactaa ttgaatcaaa
    15301 actttatcgt gtttaccgga attgaaagaa aacatgtatt ttttccattc ggttgtatta
    15361 actgtttgat caacagcttc tccaatgtta ttttgaacaa tctctccttg cttattatta
    15421 tcaaaccatc ttgcggtaaa atatccctct gctccactaa tatctacttt ggcaaaagca
    15481 gatactaaat aatcttcatt aggttctata tcaataactt gtccaatata tccatctgct
    15541 ctattatcat taattgcagt agaaggaatc atacctgagt aatgtccgtt actataactc
    15601 tcatttgaat taattattcc cctatttcta gagttccaaa acagctctcc ttgctcaaaa
    15661 tttgaatttt ttattaaatt ttcattagca aaaactttca catgaataaa tattaataaa
    15721 aataatataa ataaacttga aattaatttc ttattcttca ttttatcacc tatttactga
    15781 cctagccaag cgagatactg tatgtctcac tcctctaatt gccttgctca atgcataaat
    15841 attatcgact gttgccagtc ccccatatcc tgcgtcacct atatgttgaa tatcaactcc
    15901 acaaatttta tttctaagtg caatttcctt gatagtatct gtatcagatg tttcttggct
    15961 agtaccaata gcactcagta ctagcccacc cttactatga acgagatcaa cgacttcacg
    16021 caactcttgg tcatgaaagg ctggaacggt tccaactgct ggaacaagta tcacatccgc
    16081 acctgcttcc aacaattgct ctgcgacaga aagctctgcc acaggctcat tcactcctgc
    16141 cccgtgcatc ttacctgcaa taatcaaacc agaaaagttt tccttagcag tttgaacagc
    16201 cttaatgatt tctcgattgc taactcctgt tccaggattt ccagtcaaac agacaaagtc
    16261 aaaacctaac tcctctattc gattcaatgt ttcaacacta gcaacacgac ctgcaacaat
    16321 ttcctgtgtt tcctctagca tctttgcaga tgggtcaatc ggttccaaat ttacaccaat
    16381 tggacaagca acaagctggt gtaagcgatg aataacatca tcacctgaac tatccaaagc
    16441 ataaatttta ggctcaaaaa catcaacaca attcaataaa atcatatcag ctccaaaagc
    16501 tctagcaatt tcagaattag ttatatcccc aacaaatgtc tcacgagtaa ctacattttc
    16561 agatagaaca actctacctt cacttgctaa aatactttgt tttaattctt cagcattcat
    16621 ctgtaatatc tcagatggat ttgcactaat taaacgtttc attctcaatc ctccaataac
    16681 ttaaaccgtt tttcaatagc tattacaaat ggtaaataaa gtaagacatc caaaacaatc
    16741 aatacaattt gtaataatga accagaaata cttcctgtag caagtaaacc acttataaca
    16801 ggtggcatag tccaacttgg atctgtataa gttagcggaa ccaaacctga tgccattgct
    16861 ccccacgcta ctagtaagtt aaacattgga gctaagataa atggaactag taacaaaatg
    16921 ttcaaaacaa taggaacgcc aaacattgct ggttcattta tattaaataa tccaggtata
    16981 acagttatag gtgccaaagt ttttagttgt ttactagctt tcttcttatg tgctaaatat
    17041 cctaacgcaa gaactaaacc tatggttgca ccaccgccac ctatgaatac aaaattatcc
    17101 ataaatacgc tagtaaaaat atttggaaga gtttctccag tttgataagc tactttattt
    17161 gcatctagat tagctaacca taacggtttc ataactgcat taacaacatt tcctccgtgt
    17221 aatcctacaa accaaaaact actattaagg aaaattaaga taagaagacc aataacatta
    17281 tttcctaaaa gtccaagtgg acctcccaaa gctccttgag caatttcatg aagattaggt
    17341 aaacttaatt tatctaaagt tgcataaaca atcaaccaac caacaatagt cactgcacca
    17401 ggaataatgg cactaaagct tttagatact gctggtggaa caccatccgg catttttatc
    17461 tgtatattat gatttataaa ccattggtag atatagccat taatcaatcc taaaatcata
    17521 gcaacaaata aaccttttga tgccatgaaa gcggtaggca ttcctgctcc agcctctcct
    17581 gtaatgaaag gcgtaactgt aataaaagat gataatgaca caataccagc aggaatacca
    17641 tcaactttgt attgtctagc cataaagtaa gcgataccaa aactagctac aagaccaagt
    17701 aatccaaaac tactatcaac acccttccat aaatagtcag caacaccaat atcacctaga
    17761 tatttttccc atcctggaat aggaaaactt gcaataacca ttagtaatga acctatcaac
    17821 aataaaggta tagttagagt aataccgtct cgaatagaaa ccaacgcttt attattaccc
    17881 aatctagccg ctactggaag taacttttct tgtaataatt tttccataac cttttcctct
    17941 taaatatatt ttattatcaa aagttatcaa ttatctttat tttttgacgt caagttatta
    18001 tttgattatc ttttgttatt tatattttac aactataaga aagccttgtc aaggatttgt
    18061 gtaaatattt gattattttt tattatcaat atataataaa aagagaccag taagcaatga
    18121 aaagcttaaa aagattaaca tctacattta tccatagcaa aaaatcatag gattttaaga
    18181 atctgacaac taggaagaaa actaatatga ccttatctaa gaaacaatta caactaagag
    18241 ctaaaatact ggaaacagtt tacacattag gtcccatttc acgaattgaa atcgctacta
    18301 aaacaggaat aacacctgca acaactagca gtatcacaaa tgatctgatt aaagaaaata
    18361 ttctcttaga acttggtgaa gacgaacacg atacaagcgt agggagaaaa aaaatcctgc
    18421 tagacattca agctaaacga ttttactaca ttggttgtga actatctgaa aaacatttca
    18481 cttttgcttt aggagataat ctaggaaata tcttaaagga agagaaagaa attgttacta
    18541 aacagttaat ccaagaaaag ggaaatcaac tcattaacca gacactaaag caattcttaa
    18601 ataactgctc tgattatgaa atagaagcaa ttggaatcgc gctacctggt cgctatttag
    18661 atgattataa aataacaaca aacaatcctt tatggcaaca tatcgactta gaaatgattc
    18721 aatcccactt tgataagcct ttgtttttct ctaacaatgt taactgtatg gctataggta
    18781 aacgcctatt tagtcgccaa cagaatgacc ctaattttgc ttattttcat tttgctagag
    18841 gtatgcactg ttcttatatc tacgacggaa acatttatgg gaaaggaaat ctaatgattg
    18901 gagaaatagg gcatacagtt gtttcatctg agggagaaga atgtagctgc gggcgcaagg
    18961 gatgcttaca aacttttgct ggagaatctt ggttaatcaa aaaatcaaaa attctatatc
    19021 atcaatctcc ctattctcta cttcctagtt tagtcaaaaa tgccgatgat attgatatcc
    19081 aagttatttt aaccgcttat caattaggtg acactggaat aatcacactt atccatcaag
    19141 ccttactcta tcttagtcaa accattttaa atatcagtat gatgattgac tctcaaaaaa
    19201 tctacctaca tagtccttta ctaacaaatc aacacatcat ccaaaaacta tatagtgaaa
    19261 tgaactacaa acccaaactg ctctataatc gcctacctga agtcattatt gaaccttaca
    19321 atgattttac agccgcacac tcagctattg cactttgttt gtatcataca attctacatt
    19381 cttaattttc tattacattt aataaatagg ctaaaaagag ggagtatatc ataaaaagcg
    19441 aataaacctg ttttctgaaa atcagaattc tgttttgttc gctttcttta tatttggaat
    19501 tatactccta tctccccttt ttcataatgt atagtgaaat gaaataataa caggacgaat
    19561 cgatcgggac agtcaaatcg atttctaaca atgttttaga aatagaggtg tactattcta
    19621 gtttcaatcc actatatttt cgtacaggtg cttcaaccat ttgaacgatt tcaaatcctt
    19681 ctttttggta aagattctga gctctttgat ttgcctcgaa gacatttaga gaaatactat
    19741 ctatatcttc attttcaaag gccaaactaa caaatttcct taaagcctgg ctacctaagt
    19801 cttgctcctg tttctggggg ttgataaaaa atctcccgat atgaagattg ctgtcttcta
    19861 gcctgatttt ctggataagt cccacaaact cttgttcatc aaagattgaa aagactcctt
    19921 ccaaggcttg aaggggcagt agaaaaggaa tccttggtcc catccattgt tcttgaaagg
    19981 atttgcctag ggagttggac cactggcata caaattgagc gttttctata ctcacctttt
    20041 cttcaaaacg aattgtcatc ttttcctcac catcttatct atgtttctcc attatactat
    20101 ttctcccatt ttttacgaat agataagtat gattgatttt tatttttttc tcgtcgggag
    20161 cattctcgct tcctttcttg gtttggtcat tgaccgtttt ccagagcaat ccattatcag
    20221 ttcagccagt cactgcgatt cctgtcagac tcccttgcgt cccttagatt tgattccgat
    20281 tctctcacag gtcttcaatc gctttcgctg tcgctactgc aaagttcgct atcctgtctg
    20341 gtatgccctc tttgaactag gcttaggact cctctttctg ctttactctt gggaattgct
    20401 ttccttgggg caagtcgtcc taatcaccgc tggtttgacc ttgggtatat acgactttca
    20461 ccatcaggaa tatcccttac tggtctggat gactttccac ctaatcctaa tagcttcctc
    20521 tggctggaat ctggtcatgg tctccttcct catacttgga attttggctc attttattga
    20581 tatccgcatg ggtgcagggg atttcctctt tttagcttct tgtgctctcg tctttagcgt
    20641 aacggagtta ctgatcttga ttcagttcgc ttctgcgacg ggtatcctgg cctttctcct
    20701 gcaaaagaaa aaggaaagac ttcctttcgt gcctttcctc ttacttgcta cttgtgtgat
    20761 tatttttggt aagctactac ttgtttgata aattccaatt tctgccatat gtactccatg
    20821 aaattatttc acagttaaat tataaattat ttcttttgta caaagggatg atgttatcaa
    20881 atcgatctgt tcttctatct tcttgatact gatcaaaaaa tttcatttcg actgaaaata
    20941 tttcgcttat aaactgtaaa cgaatacttt gtttagacat tatagtcgct agactgacta
    21001 gatgattact caaaacgacg tccagaatac tctttacttt gcttggtttt ttaacaaaaa
    21061 tttgatcatc caaaggttca atcattttgt aacctttttg cgcaatttga cgataaaagt
    21121 aagaatgttg ctttggagtc aataatccta acttaaaagc tcgatactct aaagcctgta
    21181 tcgaaacatt caaatccgac ttcaataaaa tataactatc aggattgctg acacgcttgc
    21241 caaccctctc ttcaaatttg actaaaaact cttcttttgg caataaaaaa catgatgcaa
    21301 aataatttgc ttcttgctcc aaacgatcgc catcttcatt catatcttta tatttatgta
    21361 aaagaatatg tcctagctca tgagctaaat caaaatttcg acgtacagat gatttattcg
    21421 ttcccaacac aatataaggt cttcccaatt ttgaccatgc gctataagca tcagcttggc
    21481 cattaattaa tcgttccacg atatagatgc ctgaacgttc taatttataa agcaaatcat
    21541 gattatcttt tgaaatacct aatttttccc tggcataaag agccaattcc tcaatggatt
    21601 ctcccttatg ataagattca ctcactacat tacttaggtc atgaattgta atattaggta
    21661 taattacaaa actttcaaaa taatcaatca aactatctac cttatgtaaa tacatagttt
    21721 gaatatctat tgttttccgg gttgctaggt ctgcatttct aaaggcaatt acagaagaat
    21781 caaatcgaat gctctcttct tcctgttcaa aataagttaa atcaacatga aattggttgg
    21841 ccaaatgcat tttggttgat aatttaggtt tcgtttcgtt ggactcaaac tgccaaatgg
    21901 cttgttccgt taaattaatt ctctgagcta attctgctct acttaaacca tttaacagcc
    21961 gtaattcttt caatacccga ccattaaaca tttacatact ccttactact tttgaccttc
    22021 ttgtttttct attcttggaa taatttcaaa atcttctgtt tccgataatt ctgaaaaatt
    22081 aggaatatct tgatatttag cttcttcgaa atggtacgaa cttgattgaa tatactcaga
    22141 caaatcttga atcaagtgta actgaccagt tcgtgcatca ggcataacaa catctacaga
    22201 tataatattg ttttctgagt ccgcctcata agttaaaatc ataaattttt cgatattcga
    22261 atttttagta gcttgttcaa tttcttgaat catttcatca gaaactaact ccatctgaat
    22321 tggaaaggaa tgactatctt catcattttt gtaggaagaa tgttgattaa gataaagtgt
    22381 attcatctga gcatattcaa ataagtagcc actcttattt ttttgtacca aaggaaattg
    22441 gttcgtaagt cgcttcttac cctttataat taacaatact ttcccatatt tttctgtgtt
    22501 tgtttcaaat tctaaatatc cccaagtctg tcctgctaat tgtaatttat actcaaacaa
    22561 atctgctgat gcaaatgcag tatcaatatg attaggtcgc gtccatgcat aaccattcga
    22621 cactatcatt gtctctcttt tttctagacg ttcatctaca taatcttttt gccctttcat
    22681 caaagtatct acaatttttt gtgcctcaag cgaatcaaag agatcctgat tcaacataat
    22741 tcttcctcct ccaaatactt tttaatgaat tatatcattt tcttaaagaa attactacaa
    22801 taattagctt tttcttaaag ttctgtgtca gagtaattta gaaaattata tcttctatag
    22861 taaaatcaat taaaaactga acaaatttat tgggaaattc aaatcacttt ctaaaaatat
    22921 tttaggaacc gtagtgtaat attccagatt caatttacta taaaactagc ctttctcctg
    22981 caaaagaaaa aggaaagact tcctttcgtg cctttcctct tacttgctac ttgtttaatt
    23041 atttttggta agctactgct tgtttgataa agtcctgaat cggctctcct tggtggagag
    23101 cttttactat tttcgaaccg acgataacac catctgacac cgcattgaag cgttccagat
    23161 cggcttgact agatacacca aaacctgtca agactgggat gtcggccact tgatgaagtt
    23221 gcgccaagtg cttgtccaaa tctgcacggt aattgcctga tttccctgtt accccattga
    23281 tggcaacggc atagacgaat ccctccgccc cttcaatcaa ctctttctgg cgctcaattc
    23341 ctgtggtcaa gcttactaaa ggaatcaagg cgatatctgt atctgccaaa aatggttcta
    23401 caaagttggc atgttcatga ggcaggtctg ggataatcaa gcccttcaca gctgtatcag
    23461 ccagatcttt gacaaagttc tccacaccgt actgaaagag ggggttgaag taggtcatga
    23521 tgaccagtgg aatctctgtt tcaatggttt tcaaggtttc aactaaagcc tgggtagagg
    23581 tcccgtgggc taaactgcgc aagccagctt cttcgataac aggtccatct gcaacagggt
    23641 ctgaaaaggg aatacccact tcaattgcag agacacccaa atcttctaaa aagtgaattg
    23701 tttcagcaag accatccaaa cctttttcgt ggtcaccagc catgatatag ggaacaaaaa
    23761 ttccttttcc agctgcttta atagcattta atttttttgt tagtgtctta ggcatgagct
    23821 tctcccttct ttgctgcatc tgcttccaag cggtctttta cttgaaccac atccttgtcc
    23881 ccacgacctg ataggcatac aatcatagac ttttctggtc caagttcttt ggccaatttc
    23941 accgcaaagg cgatagcatg gctagattcc aaagctggga taatcccttc cacacgagac
    24001 aagagttgga atccttccaa ggcttcttcg tctgtcacag ggacatagct ggcacgttta
    24061 atatcgtggt agtgagaatg ctctggaccg ataccaggat agtccaaacc tgctgagata
    24121 gagaaggctt caagaatttg accatgggca tcttggagca catccatgag ggaaccgtga
    24181 aggacacctg gacgaccctt ggtcaaggta gctgcgtggt gctccgtatc cacaccaaat
    24241 ccagccgctt cagctccata catggctact gactcatctt ctacaaaggg atggaagaga
    24301 ccgatggcat tcgacccacc accaacacag gctactaggg catctggcag attttgtcct
    24361 gtcaagtcac ggtactgttg tttagcctct cgaccaatga cactttggaa gtcacgaaca
    24421 atttctggaa atggatgagg ccccaaggca gaaccaagga tatagtgggt atcatctata
    24481 ttagccaccc atgaacgaag ggctgcattg accgcatcct tgagcacgcg cgaaccatct
    24541 gtcacggcct cgaccttagc tcccaaaagc tccatacgga agacattgag ggcttggcgt
    24601 ttgacatctt cctcacccat gtagatggta cattccatgt taaagagggc cgcagcagtt
    24661 gcagttgcca caccgtgctg accagcacca gtttctgcga taattttctt tttacccatg
    24721 cgtttggcaa gccaaacttg tcccaaggca ttgttaatct tgtgggctcc tgtatggtta
    24781 aggtcttccc gtttgagata aatcttggct ccgccgatat gctgggtcaa gttttttgcg
    24841 taataaagag gagtttcacg tcctacgtac tggcgcaaaa gctggtttaa ttcctcttgg
    24901 aaacttgggt ctgcctgact ttcacggtag gccttctcca actccaaaac tgctgtcatc
    24961 aatgtttctg ggacaaaacg tccgccgaat tttccgtaaa atccatcttt atttggttcc
    25021 tgatatgcca tgctttaccc tctctataaa tcttctaatc ttttcatgat ctttttgtcc
    25081 atctgtctcc actccgctcg atacatctac tgcataggga gtaaaatgtt gaattgcttt
    25141 tactacatta tcttcattaa ggccacctgc gataaagaag ggctgtgcta gtccagtcgt
    25201 atccagttga ccccaatcaa aggactgacc acttcctgcc acaggggcat caaagagtag
    25261 ataatctgcc tgagaattgg ggacatgccc atttccatct acctgcacag cctgaatact
    25321 ggcacaaggc aaattctcaa ataaatcagc tgccacctga ccgtgaactt gaaccaagtc
    25381 caagccaact ttgtcaatcg cttccagcag ttctacccga cttggtgaaa caaatactcc
    25441 aacctttttc acatctgcag gaataagctt tgccaactca gctgcctctt ctaaagtcac
    25501 ctgtctttta ctaggtgcaa agacaaaacc gatatagtcg gctcctgctg aaacggctgt
    25561 ttccaccgct tctttggtcg atagtccaca aattttaacc tttgtcaatc tgcaactcct
    25621 tgattctctg ggccacattt tctgcctgca taagagctgt ccctaccaaa attccgttaa
    25681 agtatggggc tagtcgttcc gcatcctgcc ctgtgaaaat ggcagattca gaaatgtaat
    25741 agcgaccttc ctcaaagtaa ggggctaaat ctacactggt ctgcaagtcg acctcaaagg
    25801 tagtcaagtt gcggttgttg accccgataa tctcagcacc aagtctgtgg gctacctcta
    25861 gttcagctag attgtgagtc tccactaaga cttccagacc aagctctgtc gcgtagtcat
    25921 acagttcctt gaggcgttct tcggacaagg ctgccacaat aagcaagata actgtcgcac
    25981 ctgtattgcg agcgcggatg atttgctttt catctatgat aaagtctttg ttgagcgtcg
    26041 gaatctctac ctgactggaa atttcccgta gataatccaa atgcccttta aagaaaacct
    26101 catctgtcaa caccgaaatc atcactgctc cgttttcttc ataagtctgg gcctgttgca
    26161 caatatccac atcgagattg atatctccca aactagggct agctttcttg acctcagcga
    26221 ttacctgcaa gcagtcctga tgattcttca aaaattctgc caagcgatag gtctggcgca
    26281 gaggctggat ttgctccagc ttcatctgct ccacctcacg cgccttctgc tctaagattc
    26341 gtgctaaaaa ttcctgactc atttttggta ctcctgtaac agtctgagtt tttcaagggc
    26401 cttgcctcta gcaatcactt gacgggccaa ggcaactcct tccttgatgc tatcaatctt
    26461 accattagca tagaaaccaa gaccagcatt caagactgtc gtttccaaga atggacttgc
    26521 ttcgtttttc agaacgctaa gcaaaatttc tgcattttcc tgagcattcc caccacgaat
    26581 atcttccata gcatagtctt ccattcccaa atcctctgga gtaaagcttg acaagctgat
    26641 ttcgccattt tcaagaagtg caatcttggt tgttccgttc aagccagctt catccaaccc
    26701 ttctggtcca gcaaccacga tggcacgttt gcgacccata tttttcaaaa cctgagctgt
    26761 actttctagg agttctggac gactaattcc aagaagctgt gtttctaaag ccattggatg
    26821 aatcagtgga ccagtcaagt tcataatcgt tggaattccc aattccaaac gagctggcat
    26881 gatgtatttc atagctgggt gcatattttt agcgaagaga aagacgattc cagttttatc
    26941 aaagacctta cctagttcag ctggtttgag gtcaagattg attcccaagg cttcgaggac
    27001 atctgcggaa ccagatttag aagaaatcga gcggttacca tgcttggcca tgtgaatacc
    27061 gccaccagcc aagacaaagg ctgcagttgt ggaaatatta aaactgaaag acttgtcccc
    27121 acctgtacca cagttgtcca tagcatcatg aatctcagtt ggaatatgct gggcatgtcc
    27181 tctcatgact tgggcaatgg ctgtacgttc ttcaggtgtt tcccccttca tcttaagagc
    27241 taagaggaga gaagcaatct gcgcttcagt tacacgccca gttacgatac gctcaatgac
    27301 atccgtcatt tccacacctg ataaattttc aaattttgct agtttttcaa taatctcttt
    27361 catcctagtt tcctcacttt acaaccttct cgataaaatt ccgaatagaa gacaagccgt
    27421 ctggcgttcc aatgctctct ggatggtact ggaagccata aatcggtagg tttttatgtt
    27481 gaatccccat gatggcttgg tcatcagtcg aacgagctgt cacttcaaag tcttctggca
    27541 tttcctcaat caaaatactg tgataacgca tgaccgcacg tccatcctca ataccttgat
    27601 acaaaacaga tggcgcttca aagttgatat tgctctgttt cccatgcatg acttttggag
    27661 ccaaacctag cttaccacca aagacttctg caatggcttg gtgacccaaa caaatcccta
    27721 gaatcggctt cttgcctgca aaatcacaaa tcatgtcttc catctttcca gcatcaactg
    27781 gccaaccagg accaggagaa aagaccagac catctgcttt ttcagcttct tcatacagct
    27841 tggaatcatc atttctcaaa acctgaactt ctgcaaaatt cccaatgtat tgggccaagt
    27901 tataggtaaa agaatcatag ttgtcaatca ataaaatcat ggtcttagtt ctccaattct
    27961 agtcatagat tttgctttgt taatggtttc ttggtattcg ttttgggcga tagagtcgta
    28021 gacaatccct gccccagcct gcacataggc tctttgattt ttgagaatca tggttcggat
    28081 ggcaatggcc aaatccatat cacccgtcgc agacaagtag ccgattgctc ctgcatatac
    28141 gctccgtttt tccgtttcca gttcatagat gcgtctcata gctcgaattt ttggtgctcc
    28201 agaaacggtt ccagcaggaa gcgttgcttt caaggcatcc atggcagtga gttctgcaag
    28261 caaacgtccc ttgaccacac tggtcaaatg catgacgtag cggaagagct ccacctccat
    28321 atacttagta acttggacac tggccgtttc agagatgcgg ccaatatcgt tacgccccaa
    28381 gtctaccaac attcgatgtt ctgctgtttc cttctcatca gagaggaggt cagtcgccaa
    28441 ggccttgtct tcttcatccg tagcccctct tggtcgcgtc cctgcaatcg gattggttgt
    28501 cacgatgcca tttttgacag aaaccaaact ttctggacta gctccgatga tttgataatc
    28561 cccaaaatca tagaaataaa ggtaattaga tggattagtc acgcggagat ttctgtagaa
    28621 gtcaaatgga tttccagtaa cttctgctga gaaacgctgg ctgagtacac attggaacat
    28681 atctccgtta cgaatcaagt cacgagctgt ttctaccatt ccctcaaact tatgtggagc
    28741 gatatgcggt ttgaagtcaa gtggtgataa atccaagtct tcaaattcat ttggagcagg
    28801 aatgcgtaat tcctcaagca cttggttcaa ggatttttcc aaggcctctt gactgcgctc
    28861 actataaagt gcatcctcta tgacatgtat cttctccttc ttgtggtcaa agaccatata
    28921 gctctcatag acaaagaaat gcatgtctgg cgtcccaatt gtatcctcag ggatttgacc
    28981 aatttcttca taaagcgaaa tcatatcgta accaacaaaa ccaatggctc ccccaccaaa
    29041 agggaggtct gaatggtgct ggctcttatg agtcacttca taaaggaaat ccaagggatc
    29101 ccgatcaatc gcttgaccat tttgatagag aactccattt tcaaacttaa tctcaaaaac
    29161 tggattatag gctaggatag aaaaacgagc tgtttccttg tctctcggaa tactctctaa
    29221 aataacctta tgttgcccct ttaagcgcat ataagccaag attggtgata agacatctcc
    29281 atgaatgatt cgttccattg tcatttccct ttcagttcta attctagttc gtggcgactg
    29341 tatgaaaaat ccccacgcaa aataacttgc gtgaggacga aattcgcggt gccacctcaa
    29401 ttataggatt tctcctatct ctcattcctg tctcagatat ctcctgtaac aggctgtgcg
    29461 ataaagggca ctcccttgag aatgatgttt tcttctctcg tttcagatga acccaacttt
    29521 acagctttct ctgcttgttt tcagcaacca caagctctct gtgagagaaa agactgtaat
    29581 ttttccatct attatttttt agcttctagt aatctgcaat cgcagctagg tccttgcctc
    29641 cacgaccaga gacattgatg aagagatgtt catctcggta cacctttata ctcttcgaaa
    29701 atctcttcaa accgcgtcaa cgtcgccttg ccgtaggtat ggttactgac ttcgtcagtt
    29761 ctatctgcaa cctcaaaaca gtgttttgag ctgacttcgt cagttctatc cacaacctca
    29821 aaacagtgtt ttgagcaacc tgcggctagt ttcctagttt gctctttgat tttcattgag
    29881 tattactagc ttttttcgta ttagtccagc ctttttgttt acttttagta ggaggcaagg
    29941 agctgtagat agaactcaag ttcatcaaag cgacttaagg ccctaataaa agataaacca
    30001 aacgacggat agaaaaaagc ccacacacag aatatacttc cgtgtgaggg cgttggtaac
    30061 gcggtgccac ctcaattata aagggactat ccctttacat ctctgccttg tttaacaaca
    30121 agctgcactg taaggtgtgc gcaccgaatt ttcattgttt caaattcatt ttcaaaatca
    30181 gcccactttc actacttcca accacctatt cacaatcacc acaggctccc tgaagatcaa
    30241 aaatagttac ttttctgatt tgttgaactt attttaatac tttgtttttt ctttgtcaag
    30301 acttttttac gatttttttg atatcattcg aatgtgacca tatcttcctt agatcgaaca
    30361 tgaacatgtc ccacttgtta gaaattggat ccaactcaat agaaactgaa tggaggctaa
    30421 acagaactta ttttagaaca ctccatcttt tccactagga ttttcaagaa ttaaacaata
    30481 ctagaaactc tgtctcctaa caaatttagg agaaacttca acagatgtga cactttcccc
    30541 tttaataatt gctaaaacac cttctatcat ttctttagcc aatttaacat aattgggagc
    30601 aattgtagac aaagctggag tataatactg agaaatagga atattatcaa atccaatgat
    30661 agaaatatca tctggaataa gaattccttt ctcatagcac gcacgaatca agccctgaac
    30721 cttttcatct cctgaaacaa aaataatgtc cggataattt tgggtagtca agtgctgcat
    30781 tgcataagaa taaactgaat caattgtaga taagccataa atgactttta aatccataaa
    30841 gtaattttta tcattcagaa aagaacgcac acctctttca cgatccttat taacatggga
    30901 ttctcctccc ataagcaacc acatattttt aaatttttct tcagttacag ctttcatcat
    30961 atcataagta gcttgaaaat tattattaga tacatagact actccagacg tttgagattc
    31021 accgaaaaca agaaaaggca tatggttctt ctttaaatac tgaattctga tatcatctac
    31081 actttcataa aaaacaataa caccatctac taggctacct gtgcttgata taattgaatt
    31141 actaattgta tcctcctctc caaagtactc aactatagca ttaacaccaa attctttaca
    31201 cgtccgtaac actttatcta acagcgtatg aaaccaaatt aaaggaaaag agtcgatttt
    31261 ttttacagaa atcaatatat ttatagcttc ttttttagtt aaattttttg catacgcatt
    31321 tggaatatac gacaattcct ctataacttt ttgaatcgct tgataagttt cttctttaac
    31381 atttactcca ccattaataa ctcgtgaaac tgtttttgga gaaaaacctg ataaacgtgc
    31441 aatatcataa atagttacct ttttcccatt tatatttttc atttcagtcc tccattacga
    31501 acattctaat attactatac aatatttaat tttttttaac aagagaattt agtaaattat
    31561 ttaagatcca caaattcaca aaattaattt tacaaatatt cttccccttc aaaaaaattt
    31621 aaattgcatt tcacaccttt atttttaaga atgtttccaa cttcacgaca aataaattca
    31681 tatgagaaaa aactgccata aaattgtaga ttaacttttt cagtaaaatg tgtaggattt
    31741 ataaaaacat ataatagcct gtcaatgtaa cattttaaca tagagttaat tttttcttta
    31801 aagataacat ttgttatcaa ctcatcagga ggtaaatgaa aggcaaacac catttcacaa
    31861 atatcataaa aagaaataaa tttgtatact tgtatcaaac aattattatc aaaatattct
    31921 attttaccta aatcaaaatt gattttataa tctttcataa aaacctctga gcaaaaatct
    31981 actcaaaaat tagatgatta aaacatctaa aaaacaaaag gacaaaaaca tctgtccctt
    32041 tgtttactaa atttcagcta atttcttcga cataaataac acctacaata ttagcaattt
    32101 cttccatcag tcgaagatgt tcaaatctac ctgataattc cagagtaata aatgacgcta
    32161 tttttttatc tggaacatca aagtattcaa ttctgtcaga attaacatct ccaaacgctg
    32221 ttcttgaatc ggtcattctg ataccatttt ctgcacaata aaccaataca cgattatagg
    32281 cttctgtaga tttaaccact atatacaatt caatcatttt agaacgattt tgtagatatt
    32341 tttttagtgg ttggaacatg gatatcacac cccaaacaga aatggctact aaaagagctc
    32401 cctcataaaa acctactcca atagctaatc caattcctgc cgaagcccaa atgcctgctg
    32461 cagttgtcag acctgtaatt ttctttttat ctgtaataag aatcgttcca gcgcctagaa
    32521 aacccacacc tgatataact tgagctccta atcgtgtagg atctcctgtc ccaaatttat
    32581 aagatacgta ttcattcgtc atcataatca aacatgcagc tagacaaaca atactataag
    32641 ttcggatgcc tgcaggctgg gatttgctcc ctctctctaa accaattata ctaccaatga
    32701 ctactgataa aacaatcctg acaactattt caatatttga taacccaaga ctagtggctg
    32761 tcatgattat ttccttactt tacgccccgg tctttgtgtg aagtataata ccgttccaga
    32821 aataatcatc agaacaattg tataaacaaa taccagagct tgtgcattag atgttgctgt
    32881 ttcatcacct gcagatcgaa tcgtaatacc taatggttga gctaggggat ggtaaaggaa
    32941 tacagataag tcgaagtcag ttaataaaga gttaaagttt aaagcaataa cagagagaac
    33001 aaccggtaaa ataaatggaa tgataacctt catcatagta taaaaaggtg aagcacccat
    33061 acttcttgct gcatcttcca tctcatcatc aacactaaat aaaatagcac gtaccattct
    33121 ataagaaaat gggattttta caactatata tgcaataagt agaattacca aactacctac
    33181 caaaatctga ttcaagacaa gaaattgtgg ctgattaaaa gtaaataata aacttactgc
    33241 taaaagcgta cttggtaata accaaggaag tagagcacca tattcaaata agaaatcaaa
    33301 acgagattta tgttttctga caacacgagc aaatacaact gcgagaattg ttgctgttgt
    33361 cgcagcaata atagaataaa taaagctgac caagaatgga gagaatgccg cactattact
    33421 aaagaataag cgataatttt ctaaagtaaa gtttgataat gttaagttac ctgtttgaat
    33481 tgcaactgga tctgtaaatg agtataatac tataaaaatt agtggaagca tgaaaactgt
    33541 gaacaatcca tatgctacaa tgtgagcaat gatattccaa ggcttagacg caattttttg
    33601 ttttttaaga ggcgctttag tcttagagat agaaatataa tttccacctt tttctatctt
    33661 attcatgata gtaagcaaaa ttgtagttgc aatacctaaa ataattgcaa gtaaggcagc
    33721 taaatcacga gaattcccca tccctgcaaa tgtaataatc attggattta tagtttgaaa
    33781 ttctttacca ccaacaatca tgggtgctgc tactgcagat aaaccactaa gaaaaaccat
    33841 aatagtaagt gcaaatagag ttggaattaa ggttggtaac actacttttc ggaaaacagt
    33901 aaatggtttt gctcccatat ttcgagcagc ctcaatagtg tgatagtcaa cgcttcgaat
    33961 tgtatttgtt aaaaacaatg tatgattagc agttcctgaa aatgtcataa tgaataagac
    34021 tgcaccatac ccaataaacc agttagggtc taaagaaggg ataacatttt gtaaaaattt
    34081 tgtaatcaat ccatatggac catagacaaa tttatatcca gtcgctaaaa ccactcctcc
    34141 ataaattaaa gaggtcatat aacctaattt taaaatttta gcacctttaa tatcaaagta
    34201 ctctgtaaat agaacacaaa gaatacctac gacattaact gtaataatga gtgaaaatgc
    34261 taacttaaaa ctgttcataa tactctgaag tgccctctga gattttagaa cacgatgtac
    34321 agcatcaagg gaaaattctc ctccttttac aaatacattc actactagat caaagtttgg
    34381 ataaataata aatgttacta agaaccagat taaccctaaa cgaataagcc aatcttttaa
    34441 atttaattta tgacgcatac tgcacctcct taaaattgca gaacgtctga tggtgtgata
    34501 aataattcca cactttctcc gacagatcta atagcagcct gactatcaat acttgttaca
    34561 ttaagaatct gactttcaga aacttttatt gtatagtgaa ttgtaactcc agaaaactca
    34621 acatcaataa ttgtcccttt tagaatgaaa tcttgttcag tttcacgatt gaatcgaact
    34681 ttctctaatc gaatgtatcc ttttttatct tctaagaaaa cgcttgtatt tttcagtaat
    34741 acttcgtgga ctgtttcatc ggtcaaaaca ttaatatctc caataaaatc acatacaaat
    34801 tcagtttgag aattatgata aatctctact ggtgtaccga cctgttcgat gtatccattg
    34861 ttaaagactg caattctatc agataaagtc aaggcttcct cttgatcatg agtaacatat
    34921 aaagtagtaa tacctaactc tttttgaagt cttttcaact cttttctcaa atctacacgt
    34981 aattttgcgt caaggtttga caatggttca tctagacaaa gaattttagg ttcaagaacc
    35041 agagcacgag ccaatgctac cctttgttgt tgacccccag ataattctga tacattacgc
    35101 tgtaactgtt gatcagagat cttaattttt gctgccactg ctgatacttt agctttaata
    35161 acatctggag ctaccttctt aacttttaaa ccaaatgcaa tattatcaaa aacagtcata
    35221 gttggaaata gcgcataaga ttgaaataca ataccaattc cacgcttttc aggttccaaa
    35281 tgagtgacat ctgttccatt aacttcaata cttcctgatg atggatctaa aaaacctacc
    35341 aatgctctca aagtagttga tttaccacat cctgaaggcc caagaaatgt aaagaattcc
    35401 ccttcatgta tatctaaatt cagattatca attgcaacaa aatcaccata tttaatttga
    35461 atattatcaa atttaatcat ctcactaact ccctctatta ctaaaccaaa agcctctctt
    35521 tatttcttcc ttaaatttag aaataataga gagacttgga cataaaaaat aactcttatt
    35581 tcttatttta cgtattctaa ttcagctttt tctacccatt catccaaatg ctttccaaca
    35641 gcttcccagt caatattttg tggtttcact tgatcaacaa attttttcgt atcttcaggt
    35701 aactctttta gggcatcttt atttgcagga atagatccaa attttttact atattctact
    35761 tgaatttctg attgaccaaa ccaatcaata aattctttag ctaacgcttg ttttttacta
    35821 gtgcttaaaa ccatagtttg ttcagttaca aatggtacac caatctcagg agtcataact
    35881 ttgaattcaa cattttgttc tttttgtccg attaacgctc cagaacccca gatcataccg
    35941 tattgaattg ggctttcttt atctaacgct ttaacaactg agctttcacc tttttgaaga
    36001 gtataggcat ttgcaaagta ttcttttgca acttcccatc ctttttctga tacgcctaaa
    36061 tctccttttt catcaaggta acgaactaag atacttgcta gaattgcccg tcctgtacca
    36121 ccttgaagac cataaattga atatttacct ttatacttac tacctaattc agtccaatct
    36181 ttaggcattt cttttacatc aggcgcccca attaaaacta atggttgaac aatcacagga
    36241 ttataataat tatctttatc tgataaagat tgatcaattt tatctaacca tttaggcttg
    36301 tactgtacta gtaatttttg atctctaatt ttatttgagt caacagcacc aattccaaat
    36361 accatatctg caactgcatt attcttctca gcaataacac ggtctgctaa ttgagcgcca
    36421 gcaatatcaa ccatttttat attaaaacca gcttcttttg ctttagcagt taaccaatca
    36481 ccacgaccat ttgagactga gttcgaatag attactaatt cttgactttt atcagctttt
    36541 tcttcagatg aagaagcagt cgtagaattt gaacctccag agcaagcagc aagtgtagta
    36601 agagcaactc ccgttgcaag tacagtagac caaactttca tttttttcat gataagttct
    36661 ccttttttat tattttattt aaatttttcg tgatatggaa caaattgtct catatcttca
    36721 aatacagtat agtcaatacg gtttacagta atagttggaa tcttctctaa taaaatttca
    36781 gttaattctg ctctgacttt agtaaactct tcttcctcct cttcggttag aggaatccga
    36841 agatacccaa ttgaaatatg gaattgatat ctatcatgat tagggaaaca aacacctgct
    36901 ttttctgaga cataagtacg aatttcttct aatctctttg cagaagcttc atctgcaggt
    36961 tcaactagta tgttttgttt tcccatttca gttatacgca tatgaatttc ttcatccaac
    37021 aatggaaaaa tttcaagttg tttagcaaag taatcatgta tttcctgtaa aggtgtatct
    37081 agaggaagat tactgctcca aaactccgtt tcacgatttt catggcacaa caattcaatt
    37141 acagtcatgt gaatagaatt ccttggagtt aaagtaaact tatcgataaa tggtaattct
    37201 ctataacgtg attgaataat atcaacaact tccatcaaat cttgtttagt ataaagattt
    37261 gctacaactg tattcccagg gaaatgatta aattccccat tctctttgaa cttaattttt
    37321 gttaagtttt tcatataaag accttctttt ttatatttga catcggtgtc attgtgttta
    37381 cattatacaa tgaaaccgtt tcctttgtca agcgctgtca aacatttttt ttaatttatc
    37441 tttcattaaa ag
//
LOCUS       DAVAZT010000018        37031 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVAZT010000018 DAVAZT010000000
VERSION     DAVAZT010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37031
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.018"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            150..488
                     /locus_tag="VQT45_000819"
     CDS             150..488
                     /locus_tag="VQT45_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HET2359168.1"
                     /translation="MTLTIHVYYKGDGDCAIKFAREMLESGLVAEIRCQKGNLKYEYF
                     LPIEKEGIILLIDQWINQEALDEHHQSNTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            678..2114
                     /locus_tag="VQT45_000820"
     CDS             678..2114
                     /locus_tag="VQT45_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HET2359169.1"
                     /translation="MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITLGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPVTCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKKVILSNGESVE"
     gene            2166..2405
                     /locus_tag="VQT45_000821"
     CDS             2166..2405
                     /locus_tag="VQT45_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
                     /protein_id="HET2359170.1"
                     /translation="MIGSIAAILTTFAFLPQVFRVVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            2535..2849
                     /locus_tag="VQT45_000822"
     CDS             2535..2849
                     /locus_tag="VQT45_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HET2359171.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            2967..4946
                     /locus_tag="VQT45_000823"
     CDS             2967..4946
                     /locus_tag="VQT45_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HET2359172.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFAQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNSFRQYFSKENFLICTESDKVNLLEKMVESLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSYVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFISIFEKIK"
     gene            4956..5270
                     /locus_tag="VQT45_000824"
     CDS             4956..5270
                     /locus_tag="VQT45_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HET2359173.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            5301..5807
                     /locus_tag="VQT45_000825"
     CDS             5301..5807
                     /locus_tag="VQT45_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359174.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFINPSPIIIFPIMLIVFSILATVEQFKLYGNRKEKLGITLMFVRIQILISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            5887..7233
                     /gene="celB"
                     /locus_tag="VQT45_000826"
     CDS             5887..7233
                     /gene="celB"
                     /locus_tag="VQT45_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HET2359175.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            7613..7789
                     /locus_tag="VQT45_000827"
     CDS             7613..7789
                     /locus_tag="VQT45_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359176.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            8199..10412
                     /locus_tag="VQT45_000828"
     CDS             8199..10412
                     /locus_tag="VQT45_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-xylosidase"
                     /protein_id="HET2359177.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGSFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHFFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(10634..11110)
                     /locus_tag="VQT45_000829"
     CDS             complement(10634..11110)
                     /locus_tag="VQT45_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HET2359178.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            11333..14533
                     /locus_tag="VQT45_000830"
     CDS             11333..14533
                     /locus_tag="VQT45_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HET2359179.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSADASTRVIEAKDGA
                     ITISSHEKLRAAVHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESDKDKRLWNSA
                     TTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQPSEDYQTD
                     KQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKEV
                     KKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSIS
                     SQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEW
                     MHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPE
                     HFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFY
                     QDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPL
                     LVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQS
                     DSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFG
                     LSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTET
                     DAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLG
                     SNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSK
                     KNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYML
                     IPNVGRATFNQMIKELERSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLK
                     RGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKNH
                     SDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            14913..15298
                     /gene="tnpA"
                     /locus_tag="VQT45_000831"
                     /pseudo
     CDS             14913..15298
                     /gene="tnpA"
                     /locus_tag="VQT45_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(15677..16306)
                     /locus_tag="VQT45_000832"
     CDS             complement(15677..16306)
                     /locus_tag="VQT45_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HET2359180.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(16316..17317)
                     /locus_tag="VQT45_000833"
     CDS             complement(16316..17317)
                     /locus_tag="VQT45_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HET2359181.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(17348..17989)
                     /locus_tag="VQT45_000834"
     CDS             complement(17348..17989)
                     /locus_tag="VQT45_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HET2359182.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(18008..18823)
                     /locus_tag="VQT45_000835"
     CDS             complement(18008..18823)
                     /locus_tag="VQT45_000835"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HET2359183.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            19094..19522
                     /locus_tag="VQT45_000836"
     CDS             19094..19522
                     /locus_tag="VQT45_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2359184.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPVKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEDFESGI"
     gene            19534..20724
                     /locus_tag="VQT45_000837"
     CDS             19534..20724
                     /locus_tag="VQT45_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HET2359185.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSAQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            20735..21226
                     /locus_tag="VQT45_000838"
     CDS             20735..21226
                     /locus_tag="VQT45_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET2359186.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLACNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            21241..22020
                     /locus_tag="VQT45_000839"
     CDS             21241..22020
                     /locus_tag="VQT45_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET2359187.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTANHVVEEEAHDDWI"
     gene            22007..22825
                     /locus_tag="VQT45_000840"
     CDS             22007..22825
                     /locus_tag="VQT45_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2359188.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVVIGIIGSWLKIIA"
     gene            22825..23118
                     /locus_tag="VQT45_000841"
     CDS             22825..23118
                     /locus_tag="VQT45_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET2359189.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQTEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            23140..25041
                     /locus_tag="VQT45_000842"
     CDS             23140..25041
                     /locus_tag="VQT45_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HET2359190.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDMLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSNKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDICVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            25101..26102
                     /locus_tag="VQT45_000843"
     CDS             25101..26102
                     /locus_tag="VQT45_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2359191.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(26212..26547)
                     /locus_tag="VQT45_000844"
     CDS             complement(26212..26547)
                     /locus_tag="VQT45_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359192.1"
                     /translation="MKSLARLLNIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(26558..26800)
                     /locus_tag="VQT45_000845"
     CDS             complement(26558..26800)
                     /locus_tag="VQT45_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359193.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(26811..27353)
                     /locus_tag="VQT45_000846"
     CDS             complement(26811..27353)
                     /locus_tag="VQT45_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HET2359194.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIVLFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            complement(27369..27563)
                     /locus_tag="VQT45_000847"
     CDS             complement(27369..27563)
                     /locus_tag="VQT45_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2359195.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            27729..28679
                     /gene="rsmH"
                     /locus_tag="VQT45_000848"
     CDS             27729..28679
                     /gene="rsmH"
                     /locus_tag="VQT45_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HET2359196.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            28691..29008
                     /gene="ftsL"
                     /locus_tag="VQT45_000849"
     CDS             28691..29008
                     /gene="ftsL"
                     /locus_tag="VQT45_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HET2359197.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            29012..31264
                     /gene="pbpX"
                     /locus_tag="VQT45_000850"
     CDS             29012..31264
                     /gene="pbpX"
                     /locus_tag="VQT45_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HET2359198.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDSFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAVYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            31266..32246
                     /locus_tag="VQT45_000851"
     CDS             31266..32246
                     /locus_tag="VQT45_000851"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HET2359199.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNMGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLSFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            32855..34960
                     /locus_tag="VQT45_000852"
     CDS             32855..34960
                     /locus_tag="VQT45_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET2359200.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQEKVIGQDKAVEVVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVVIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            35683..36702
                     /locus_tag="VQT45_000853"
     CDS             35683..36702
                     /locus_tag="VQT45_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic biosynthesis protein"
                     /protein_id="HET2359201.1"
                     /translation="MSNTLKQLLLFREEFIKNILNGIDVDETVVIENDFVEELENFLK
                     ENDLLDFSNSIFFQLSGDKVIVNNIYPGYLAYFNRFLTFYPKIFAIKEVGEYIDFLNF
                     EKRIADMFYCWGFNANSRVLTAEKIIEIPNHQINAKYIKKVIKMSELLFGVDSNNRIR
                     LLNNRRELIKTIFQGSVIKSAIPALAATLDTISNSGSFQISLSKQIINNLVLSGKDKV
                     TIPRIELDNVVLSRQKIIVSVSYINDFLDLRFPDKIEYILNFLEGSGFNTKVMVYFGK
                     IVEEDKNYFVNLEKPQYFDFTSILFNKLFFKELNKFDYMVIEELIPNLDEDVMMTEYI
                     KEYTE"
     gene            36715..>37031
                     /locus_tag="VQT45_000854"
     CDS             36715..>37031
                     /locus_tag="VQT45_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359202.1"
                     /translation="MILSKVRCYIYNSKIRGKVLYELYEFINENKQLMDAINSIKVDS
                     SNGFSIQILHLGEQQTTVLLTDFFTKTLDLFKEFRVTNKSTLEQVKNQISILNSSGPK
                     MDLT"
BASE COUNT        11788 a         6024 c         7932 g        11287 t
ORIGIN      
        1 atcgctataa gaaaaaatca ttttattggt ataaagaagt gattgaaagt aatggcgaaa
       61 cgttagataa ttagttcata aaaaacaagt ttagatcctc atctaaactt gtttttttaa
      121 aattgaagga tgattttgga ggatatgaga tgacattgac tattcatgta tattataaag
      181 gcgatggaga ttgtgcaata aagtttgcaa gagaaatgct tgaatctggg cttgtcgcag
      241 aaattagatg tcaaaaaggt aatttgaaat acgaatattt tttaccaatt gaaaaagagg
      301 gaattattct ccttattgat cagtggataa atcaagaagc tttagatgaa catcatcaat
      361 caaatacaat gcagaaaatc ttagatttaa gaaaaaaata tcacttgcag atgcaagttg
      421 aacgttatat agaagatgat tctgggatgc cagaaagcga taagtcgttt atagacacag
      481 ggaattagaa ttattgtgag agtttttgta gtttgaaagt attgaaaatc gtaaagatat
      541 cattacgaga atacaagaag atattgttct atttccatta aaaattactt ctttccttaa
      601 taataaggaa aaagaatacg ttttcatctt ttggtttgag gtttataata agaatatcaa
      661 agtcaggagg aaaaaagatg actactttta aagatggatt tttatggggt ggtgctgttg
      721 ctgctcatca acttgaaggc ggatggcaag aaggtggcaa aggaattagt gttgctgatg
      781 ttatgactgc tggtcgccat ggagtagctc gtgaaattac tttgggagtt ttagagggta
      841 aatattatcc aaatcatgag gcgatagatt tttatcatcg ttataaagaa gacatagcac
      901 tttttgctga aatgggattc aagtgcttcc gtacctctat tgcatggaca cgtatctttc
      961 caaaaggtga tgagttagag ccgaatgaag aaggattaca gttttatgat aatctttttg
     1021 atgaatgctt aaagaatggt attgaacctg tcatcactct atctcatttt gaaatgcctt
     1081 atcacttagt gaccgaatat ggtggttgga aaaataggaa attgattgat ttctttgctc
     1141 gttttgcaga agtcgtattt aaacgttaca aagataaggt taaatattgg atgactttca
     1201 atgaaatcaa taatcaagcg aattatcagg aagattttgc accatttact aactcaggta
     1261 ttgtatatga ggaaggtgat aatagagaag caattatgta tcaagcagca cattacgaat
     1321 tagttgcttc tgcacgagct gtaaaaattg gtcatgagat taatccagat tttcaaatag
     1381 gttgtatgat tgcgatgtgt ccaatttatc cagttacttg caatcctaag gatatcttaa
     1441 tggcaatgaa agctatgcag aagcgttatt attttgctga tgtgcatgtt ttaggtaaat
     1501 atcctgagca tattttcaag tattgggaac gaaaaggtat ttcagttgat tttactgacc
     1561 aggataaaga agatttactt ggtgggactg tagattacat tggtttcagt tactatatgt
     1621 cctttgctat agactctcat cgtgaaaata atccttattt tgattatctt gaaacagaag
     1681 atttagtgaa aaataattat gttaaggctt ctgaatggga gtggcaaatt gatccagaag
     1741 gtttacgtta tgcgttaaat tggtttacag accactatca cttaccactc tttattgttg
     1801 aaaatggttt tggagctata gatcaagttg cagcagatgg tatggtacat gatgattata
     1861 gaattgaata tctaggtgcc catattcgtg aaatgaaaaa ggctgtagtt gaagatggtg
     1921 ttgatttaat gggttatact ccatggggat gtattgattt ggtttcagct ggtaccggtg
     1981 aaatgcggaa acgttatggc tttatttatg tagataaaga tgacaatggg aagggaagtt
     2041 ataatcgttc cccgaaaaaa tcttttggct ggtataagaa agttatttta tctaacggtg
     2101 aatcagtaga atagtataaa caaactgaga ttattctcag tttgtttagc atattgagga
     2161 gacatatgat tggaagtatt gcagcaattt taacaacatt tgcattttta ccacaagttt
     2221 ttcgtgtagt taagacaaag gacacaggat ctattgctct aggtatgtat gttatgcaag
     2281 ttattggtat tgcattgtgg cttgctcatg gtattcgtat aggagacttg cctttgattt
     2341 tagcaaatag tgtttcattt ctactctcag gaataatttt attttataaa ttgaagtata
     2401 aataattttt ttccatatca tttaggaaaa tgagggaatt gtcattgaaa acgctttatt
     2461 ttataataaa aatagataac aaataagcca acttagcaca gctttgattg gatttaagaa
     2521 aaggagaaaa tattatggca aaagctttaa ttatttgtgc agcaggaatg tcttcatcac
     2581 ttatggcaca gaaaacaaca gagtttctaa aaggaaaagg gaaagatatt gtagttgatg
     2641 ctattagtgc tactgaagga gggaaagcta tcgcagcagc agcttttgat ttgtatcttg
     2701 tcagtcctca aacaaaaatg tactttaagc aatttgaaga ggctggttct aaagcaggaa
     2761 aaccagttgt acaaatacct cctcaagcct atattcctat tccaatggga attgaaaaaa
     2821 tggctaattt gattcttgag aatatttgat gaacacatga aatgtcaata aatatttaag
     2881 ttaagataaa ttgttttgag tttgatataa attgatttaa gtgtataata tgcttcaata
     2941 tatgaaaaca tacgttttag gagggaatga atgtgttaaa cattaaagag aaagatatcc
     3001 ttcaattttt aataaaaaat aaggaacgtt ttgttacaag caaagaactg gcagaatatt
     3061 tatcctgttc agatagaact gtccgtaatg tactgaaatt aattgagaag acaatgatta
     3121 ttcaaggagt ccggttgatt tcaaaacaag gtcaagggta tcaaatattt tttgagaatc
     3181 aaggcgctta ccaggagttt agacaaactt atgaactgga agaagactat acgaaaactg
     3241 cggtttcaaa aggtgatgat cgtttagtat ttatcttaaa taaattatta tttgagcaag
     3301 ttccagttct ttttgatgat ttagctgatg aactttacgt tagtcgttca acattatctc
     3361 atgatttcag aaagatacga gtgatgttat cagagtataa tttgtccatt gagagtaggg
     3421 cgaataaagg agtttatgtc tcaggcgagg aacgtgataa acgacgtttt atcataaatt
     3481 atttcctaga gaatcaattt tttaaaacaa tacattgcta tgtaaaattt aacttttttg
     3541 ctcaaactgt tccattagaa gaatttgcta gaattgtttt ggatgaatgc caagaggcca
     3601 acctaaaact atctgatttt gtactacaga atttagtagt tcacatagca ttgtctgtga
     3661 ttcgtttaaa atccggattt gaaataaaaa atatagactg tcagatgact gatgatgcaa
     3721 tagagagaaa ggttgctcaa agaattcttt ctaaagtaag agaagtaaca aatcaggaat
     3781 ttccagttca ggaaatagac tacattactt tgcatttgtt agctaagagt caacaatgtc
     3841 aaaaaaatca gaagaatatt tctgaagaag ttttaaaaaa atctttattt aaaacatttc
     3901 agaatttagg attagatgat atgtataact tttcttcaga tttccaacta attgaaggat
     3961 tgataactca tctaatgaca ctacaagtac gtttagaaag ccggattacc ttaaataacc
     4021 ctttggtaga tgaaattaaa cagaattata gtgatatatt ctttatgact agagaaattc
     4081 ttgcaaatat ggacaagttc ttggagtgga caatatcaga tgatgaagta gcatatgtaa
     4141 gtcttcactt tttagctgct atggaacgta gcaaagagag tactaagttt aatattcttg
     4201 ctatttgtgc aacaggattt ggtgcagccc aaatgttaag aaatcgtttg gaaacggagt
     4261 ttgggaagcg agtagaagtt gttgatgtaa taggctatta tgaattgaat caagaaaaac
     4321 ttaaaggaat agattttata gtgtcagctg ttgatttatc aaatctatat tttcaaattc
     4381 cagtttttaa agttagtgtg tttcttaaga gtgatgagat ggaaatgatt agaaaagcta
     4441 tggatcagat gcaagtttct agttatgtac aatcatcaaa gattaataaa tttgaaaaca
     4501 acagctttag acagtatttt agtaaagaaa attttttaat atgtactgaa tcagacaagg
     4561 taaatttact tgaaaagatg gttgagagtt tatctgttgg tgaatcaaat gagtttgaac
     4621 aatctttact ttatggaatt aaacagcgcg aagaattaag ttcagttgtt ttttctgaaa
     4681 aaattgcagt tccgcatcct attcagccct ttggtacaga gggaaaggtt tcggttgcaa
     4741 tctgtaaaga ttcgttactc tgggataatc aaagttcata tgtccagcta gtatttcttc
     4801 tatctccatc aatatatggg aacgaaggtt tggcaactgt gactaaaaag atagtctctc
     4861 tgacagagaa tgatgagttg caaaatcagc taatatcttg caataacttt gaagatttta
     4921 ttagcatatt tgagaagata aaataggagg ttcatatgaa tcaagaggaa ctgcaggttg
     4981 cagcatttga aattatcctg cattcgggaa atgcaaggtc agaaatacat gaagcatttg
     5041 caaaaatgag agaaggtagt tttgatgatg cagaaagtaa attaaatcaa tcaaatgaga
     5101 taattcttga agcgcatcat gcacaaacca aactcttgca agaatacgca agtggagtgg
     5161 aaattaaaat tgaaattatc atggtacatg ctcaagatca tttaatgacc actatgacat
     5221 tattagaagt agcaaaggaa atgttagctc tttataagaa agttaactaa atatgtgttg
     5281 ttatataagg aggaaatgat atggataaaa aagaacgaca aaagattgaa caacaacgtc
     5341 gagagatggc tctaactaat acttttttta atcgatatct tcttctacgt tattcaatag
     5401 cactcttctt ttttgggaat atttattggc ttttgaatca gtttattaat ccctcgccta
     5461 ttattatttt ccccattatg ctcatagtat tttctatttt agcaactgtt gaacaattta
     5521 aactctatgg aaataggaaa gaaaagttgg gaataacact aatgtttgtt agaatacaaa
     5581 tacttatttc aataggatta cttgttttaa cttggacaag ttggtttaag aatctttttc
     5641 cgatttttga aaataaccaa gtagcacgtt tatttgtttt tgtagttctt ctattaggtt
     5701 tagttctgag tttgttagac attagaagaa ttaaaaaaat ttataaacga acagataagg
     5761 cttatcaaca atttgtccaa ttggaaaaga actcacttag tttataatcc tgatctagta
     5821 taatttgtat ttgaaactag tctttagaaa gtaaaaatta ttatgtttta ttaaggaggt
     5881 ctatttatgg atcaacaaaa cgggttgttt ggttttcttg aaaaccatgt tatgggacca
     5941 atgggcaaac ttgctcagtt taaagtagtg cgtgctatca cggctgcagg tatggctgct
     6001 gtaccattta ctattgtagg atcaatgttt ttggtattca gtattttgcc acaagctttc
     6061 tcattttggc caattgtggc agatattttc tctgcttcat ttgataaatt cacatcactt
     6121 tacatggttg caaactatgc gactatgggt tctctatctc tttatttcgt tctatcactt
     6181 gcatatgaat tgacaaaaat ttatgcagag gaagaagaac tcaatatgaa tcctcttaat
     6241 ggtgccttgc tcgccttgat ggcttttgtc atgacagtac cgcaaatcat ttttgatggt
     6301 ggaatgatga agactgtgac aagtctaaaa gaaggtgcag taattgcaga tggatgggca
     6361 atgggaaatg gagtcgcacg ttttgggaca acagggattt ttaccgcaat cattatggca
     6421 attgtgactg ttcttattta tcgtatgtgt gttaaacata attgggttat taaaatgcct
     6481 gaagctgttc cagaaggagt ttctcgtgga tttaccgctt tggttccggg atttgttgtt
     6541 gcatttgttg ttatctttat caacggtctt cttgtagcaa tgggaacaga tatttttaaa
     6601 gtcattgcaa ttccatttgg ttttgtatcc aatctgacta attcgtggat tggtttaatg
     6661 attatttatc tattgactca actactttgg attgtaggta tccacggtgc gaacattgtt
     6721 tttgcatttg ttagtccaat tgctcttgct aacatggctg aaaatgctgc tggcgggcac
     6781 ttcgctgttg caggtgaatt ttctaatatg tttgtaattg caggtggttc tggtgcaact
     6841 ttaggactat gtttatatat tgcttttgcc tctaaatctg aacagcttaa agcaatagga
     6901 cgagcatctg tagttccagc cttatttaat attaatgaac cattaatttt tggattacct
     6961 attatctata atccagcctt ggctatacca tttattttag caccaatggt tactgctact
     7021 atttattacg tagcgaattc tctaaacttt attaagccaa ttatcgcaca ggttccatgg
     7081 ccaactccag tagggattgg agctttctta gggacagcag atcttcgagc tgtattagtt
     7141 gctctagtat gtgcatttgc agcattctta gtctatcttc cattcatccg tgtatatgat
     7201 caaaaattgg tgaaagaaga gcaaggtatc taataagtaa aaaagtatac tcgatgatag
     7261 aatccatata gtttaaataa tgagtgttaa tattagcagt gaagaggtct ttttaagata
     7321 ttcttctctg ctttttcata ttttttcgct atgtagggta tgaagcaaaa tagaaagtag
     7381 ttcgaatagt tgataaacag gaaactgctg ttatttaaaa aaaacaataa agtaaagtat
     7441 gttatcgtag aatacgatac aatagtaaaa aagcaaaaag aatgcgtttt atatttgggt
     7501 ttgaggttta taaaatagga taagcgtgct gaaaacttag atatgacaaa caaaataaaa
     7561 tttttaaaag ctacatagaa acatggtata atgtatctaa aggaggtagc atatgtcctt
     7621 agatatagat aaagaaaaga tgacaatcat gggaatagct tttgaaaaca gatccgtttt
     7681 taagagtgtt tggtatgctt taagtacaaa tatgattgaa ggatggcgac ctacggttag
     7741 tgatgttgaa aaattacgag atgaagctct tgctctgggg atgacttaat gaagcgcaac
     7801 tgttatgagt cttatgacta tgttgatccg gataatttat ataccgatcc gggttcttca
     7861 gttctaagaa ataagcagga aggaaaaaag cacgcgagct tgaatatcgt atgattgcta
     7921 gtaagagttt gaaattattt atcaatccta tcttagttaa tagtttaaaa gtagtttgtt
     7981 tcacaactgc ataagcttag aaaagttgaa aagtgataac tctttaataa actcttggtt
     8041 tgttaaaaga tattttgtcc actacatttt ttcaattgac tattatttgt catagatata
     8101 acagatagaa cagatagaac attgcattca gaataatgaa aaacgcatca aaaatggtgc
     8161 gttctgtttt tatgctacca taaaaggagg aaaacaaatt gaaaattttt aagggagagt
     8221 tttatcgaat ctctgtatta acagacaagc tagtaaggtt agaatactct caaactggaa
     8281 gttttgagga tagaacgaca caacttatct ataatagaga ttttggccaa gtttcgttag
     8341 attatatcga gacatcaaac gtactagata ttatgacgga ctattttcat ctgcacttta
     8401 ataaaggaga atttaacgcc gaaaatttat ttatagaatt aaaaggaaat tttgccgtat
     8461 atggtagtcg ctggtatttt ggtgaatcta ttgaaacgtt aaaaggaaca gctcggactc
     8521 tggataaggc agatggagca atctcgttag aagatggaat tattagccga aatggtatag
     8581 ccttattgga tgattctcaa ggatttattt gggatgaaca atctggttat attgagagag
     8641 aaaatcaaat tgacctgtat ttctttgcct atgggcatga ttatagagga gcaatcagag
     8701 acttttacca tttgactggt tcaacaccct tgttgccaag atatgcttta ggcaattggt
     8761 ggagtagata ttggccttat acgtcggatg aatacttgga tttaatagac agatttgaaa
     8821 cagagaaaat tccattatct atcggtgtgt tagatatgga ttggcatata actgacattc
     8881 cagctcgttt tggaagtggc tggacaggat atagttggaa tagaaactta ataccaaatc
     8941 cagaacagtt attgcaacaa cttcatgata gaaagttaaa actctcctta aatgtccatc
     9001 ctgctgatgg gatacgggct tatgaagaag cttatcctca aatcgcaaaa cggttggggt
     9061 taaatgtaga actagaagaa cctgctattt ttgatttttt taatccctct tttagggaag
     9121 cctactttaa agatgttcat tatgagctag aaaagcaggg agtagatttt tggtggattg
     9181 actggcaaca agggacacaa ggtatgctag atccactttg gcttttaaac cattatcact
     9241 atcaggatag ttgtaaaaat gcagaaggtg gtttgatttt atcaagatat gcaggtcctg
     9301 gtagtcaccg ctaccctgtt ggtttttcag gggatactat tattagttgg aattccttaa
     9361 ggtttcaacc ctattttaca gcgacagcat ctaatatcgg ttatagttgg tggagtcatg
     9421 atatcggtgg acatatgttg ggggattatg acgaagagct acaaactaga tggctacagt
     9481 ttggtgtttt tagtccgatt actcgattac atagttctag aagtcctttt aatagtaaag
     9541 aaccttggtt cttttcagaa acaacatcta agattatgaa gaaatacctt cgtttgagac
     9601 atcagatgat tccctatcta tataccatga atgtaaagac acatgaggaa ggtgccccat
     9661 taatcagtcc aatctattat ttctatccag agaatgatga gagctataat gttccaaacc
     9721 aatacttttt tggaacagaa ctgatggtgg ctcccattgt agaaaagatg gatttgacat
     9781 tccaatctgc aaaagtagat gtatggttcc ctgaaggtga atggtatgac ttcttttcag
     9841 agaaaaaata cacaggtggt gtgaagttaa gtgtttatag ggacatctcg actacgcctg
     9901 tgtttgcaaa aagtggtgca atcattccct tggttggttc tgagataggt atgggtgttg
     9961 atttacctga ggttgtagat tggtatgtat tcccagggaa acaacatttt tttgaaatgc
    10021 ttgaagatca aaatggtcaa agatataaaa caagattatc aatcgattgg gaaatgggaa
    10081 tggtagagtt agcattacaa ggagattcta gtatcgttcc aagcaataga aaacatagaa
    10141 ttcattttaa aggaacgaat gtgtctataa ttgaattgcc aaataagaat gatacagcta
    10201 aatttgaatg gaaagataat aaaaggacat ctttaaatga cgaagttttt agactactaa
    10261 agacagcttc tcttccatat gaattaaaag atagattgtt aaatcaattc atcaatgcga
    10321 aaaactctca tgacttaatg aatatcttgc atcatcagga taaggaattg agagggcgtt
    10381 tgttggaaat gatatttact agccaaaact aattgaaata attagaaagt catttgttta
    10441 gtgtatatga agattctgta tggtattcgt tatcactggt cacattgaaa atgtgaaata
    10501 agcacctaca acatagactt tacaacactt catgtttcat atcatggggt gtttttctat
    10561 ttaagtcaaa gcccatcaaa aaatctcact attcatcagg ttaaaggaaa cctaatcata
    10621 gtgagattgt gaattatagt agagtttgta tcgcctcttc aatttgtttt gggtctgttt
    10681 ttgaagaaaa gcgttcaaag acttgcccat ctcgaccgat gagaaactta gcgaaattcc
    10741 attcgattcg ttttcctagt gggccggatt tctggtcttt taaccagaca tagagagggt
    10801 ctgcttcctt accgttgacc ttaatcttgg caaaacgtgg gaaggtggtt tgaaaatgta
    10861 ggctacagaa ggcgttgatt tcctctgcgc tgccgggtgc ttgtcccata aactgattgc
    10921 aagggaaatc caatatttcg aagccctgat cttgatagcg ttcatagagt tcttgaagtc
    10981 cctggtactg gggcgttaaa ccacatccag tagcagtgtt gacaatcaag agaactttgc
    11041 cacgatagct atccaaggga gttgcttggt tgttttggtt caaaacggaa aaatcataaa
    11101 gtgaagtcat gagggcctct tttctttttc tacattgtaa cagtttttac ttttttcgtc
    11161 gagtcggatg gaagatattg ttgaagaata agccttcaat atgatagaaa ccgtttacaa
    11221 ataactttaa aaatggtatg atttaattaa accggtttac ttagttgcta taaatctcta
    11281 atttgagatt tagttcctat tgattttaca atatgtttat tggagtgtat acatgcaaac
    11341 aaaaacaaag aagctcattg tgagtttgtc ttcacttgtt ttatcaggat ttttattaaa
    11401 ccattatatg acagttggag cggaagaaac gactacgaat accattcagc aaagccagaa
    11461 ggaagttcag tatcagcaaa gggatacaaa aaatttagtt gaaaatggtg attttggtca
    11521 gacggaggac ggaagcagtc cgtggacagg aagcaaagct caggggtggt cagcttgggt
    11581 agaccagaag aatagtgcag atgcctcaac tcgagtcatt gaggctaagg atggggctat
    11641 cactatctca agccatgaga aattaagggc agcggttcac cgtatggttc ctattgaagc
    11701 taagaaaaag tataaactgc gtttcaagat taaaacagat cataaagtcg ggattgccaa
    11761 agttcgtatc attgaggaaa gtgataagga caagcgattg tggaattctg caacgacgtc
    11821 aggaacaaag gactggcaga ccattgaagc agactatagc ccgactttag atgttgataa
    11881 aatcaagctg gagttattct atgaaacagg aactgggact gtttccttta aggatattga
    11941 gctggtagag gtagcagacc agccttctga ggactatcaa acagataaac agcttgagga
    12001 aaagattgat ttaccaattg gaaaaaaaca tgttttttct cttgcggact atacttataa
    12061 ggtagaaaat cctgacgttg cttcagtcaa aaatggaatt ttagaacctc ttaaggaagg
    12121 gacaaccaat gtcattgtca gtaaagatgg caaggaagtg aaaaagattc ctttgaagat
    12181 tctagcctct gttaaggatg catacacaga ccgtttggat gactggaatg gcatcatcgc
    12241 tgggaatcaa tactatgatt ctaaaaatga acagatggcc aaattaaacc aggaattgga
    12301 aggaaaggta gctgatagcc tatctagtat ttcaagtcag gcggaccgca cctatttgtg
    12361 ggaaaaattt tcaaattata aaatgtctgc aaatctgact gccacttatc ggaaattgga
    12421 ggagatggcc aagcaagtga ccaatccttc ttctcgttat tatcaagatg aaactgtcgt
    12481 tcgaacagtc agggattcca tggaatggat gcataaacat gtctacaata gtgaaaagag
    12541 cattgttggg aactggtggg attatgaaat cggtacacct cgtgccatca acaatacctt
    12601 gtctctgatg aaagaatact tctctgatga ggaaattaaa aaatatacag atgtgattga
    12661 aaaatttgta ccagatcccg aacatttccg aaagacgact gataacccat ttaaggctct
    12721 aggtggaaac ttagttgata tgggaagagt aaaagtaata gctggtttac tgcgtaagga
    12781 tgatcaagaa atttcttcta ccattcgctc gattgagcaa gtgttcaagt tggtagacca
    12841 aggtgaaggt ttttatcaag atggatccta tatcgaccat accaatgttg cctatacggg
    12901 tgcttatggg aatgttttga ttgatggcct gtctcaactg ttgccagtca ttcaaaagac
    12961 caagaatcca atcgataaag ataaaatgca aaccatgtac cactggattg ataaatcgtt
    13021 tgctcctttg ctggtgaatg gagagctgat ggatatgagt cgtggacgct cgatcagtcg
    13081 tgcaaatagc gaggggcacg tggccgcagt agaagtacta agagggattc accgaatagc
    13141 ggatatgtct gaaggagaaa ccaaacaacg tttgcagagt cttgtgaaga ccattgttca
    13201 atcggatagt tattatgatg tctttaagaa tttgaagact tataaggata tcagtttgat
    13261 gcaatccttg ttaagtgatg caggagtcgc aagtgttcca agaacaagtt acctatctgc
    13321 ctttaacaag atggataaaa cagccatgta caatgcagag aaagggtttg gatttggctt
    13381 gtcactcttt tccagtcgta ccttgaatta cgaacacatg aacaaggaaa ataaacgtgg
    13441 ttggtatacg agtgatggga tgttctatct ttacaatggc gatttgagtc actatagcga
    13501 tggctactgg ccaacagtta atccatataa gatgcctggt acaacagaga cggatgctaa
    13561 gagagcggat agcgatacag gtaaagtttt accgtctgct ttcgttggaa cgagcaaact
    13621 agatgatgcc aatgcgacag caaccatgga tttcaccaac tggaatcaaa cattgactgc
    13681 tcataagagc tggtttatgc taaaggataa gatcgccttt ttaggaagca atatccaaaa
    13741 cacttcaaca gatactgctg caactacaat tgaccagaga aaactggaat caagtaatcc
    13801 atataaagtc tatgtcaatg ataaagaagc ctcccttaca gaacaagaaa aggattatcc
    13861 tgaaacccaa agtgtctttt tagaatcatc cgattcgaaa aagaatattg gttacttttt
    13921 ctttaagaag agttcaatca gtatgagtaa ggctttgcaa aagggagcct ggaaggatat
    13981 caatgaagga cagtcagaca aggaagttga aaatgaattt cttacgatta gtcaggctca
    14041 taagcaaaat ggagattctt atggctatat gctcatccct aacgtgggtc gtgccacctt
    14101 caatcaaatg ataaaagagt tagaaagaag cctcatcgaa aataacgaaa cccttcagtc
    14161 tgtttatgat gccaaacaag gagtttgggg cattgtgaaa tatgatgatt ctgtctctac
    14221 tatttccaac caattccaag ttttgaaacg tggagtctat accattcgaa aagaagggga
    14281 tgaatataag attgcctact ataatcctga aacccaggaa tcagctccag atcaggaagt
    14341 ctttaaaaag ctagagcaag cagctcagcc acaagtacag aattcaaaag aaaaggaaaa
    14401 atctgaagag gaaaagaacc attcggatca aaagaatctc cctcagacag gagaaggtca
    14461 gtcaatcttg gcaagtctag ggttcttgct acttggggcg ttttatttat tccgtagagg
    14521 aaagaacaac taatttgttc atcatctaga tgaattacat gaaactgtgg aaaatagaaa
    14581 aaatccgaag aaggccaaat atcttcggat ttttctttta aaaaaggata agttgatact
    14641 tatccttttt acttcattat gtgactatag cgttttgaaa ctagaatagg acatcataac
    14701 tgctaaaaga tttctataaa ttcatttgat tttcctaatc aatttattcg tatcctattt
    14761 cactctacta tattagtccg tctcgcacct cacggagcga gacaaaacaa ccacccgcta
    14821 tgcgggtgcg cgtcgaaggt tataccaaaa aaactccaaa cgcgatacaa taaaggtgtt
    14881 caatccactt gtaaagcgaa aggagaaaaa atatggcaca aaaggctcat agtttatctc
    14941 acacaaagtg gaggtgttct atcacattgt gttcacccct aagtatagac gaaaagtcat
    15001 ctataatcaa tatagaagta gtttaggcga aatatttcat cgcttgtgta gttataaagg
    15061 tgttgaaatg atcgagggtc acttaatgcc agaccatgta cacatgttag tcagtattcc
    15121 actaaggcta agtgtttcga gtttcatggg ttatttaaaa ggaaaaagtg cactcatgat
    15181 gtttgacaaa cacgccaatc tcaagtacaa gtttgggaat cggcatttct gggtggaagg
    15241 ttattatgta agtccagtag ggcttaatga agccacaatt aagaaatata gtcaagatta
    15301 aagaaattat ccagtggatg atttcttcac gagtatgaaa atttgagaac tagtaaagta
    15361 tgatatatag taaaatgaaa taagaacagg acaaaatcga tcaggacagt caaatcgatt
    15421 tttaacaatg ttttagaagt agaggtatac tattccagtt tcaatctact atagcactag
    15481 ataaattgag tgtaaaagaa tatgaggatc cctttaggga tagtggtaag taataccaaa
    15541 gtctcttaaa gaggcaagtg acgagtcaag agcaataagg cttgaacaac gtaaaagcca
    15601 gcgtctttag gcgctggctg atgatttggg cttatagctc tgggataaac cacccgttag
    15661 acgggtagtt atgattttat ctgagtgtaa tatactgttg ggcaatctcg ctgatgcggt
    15721 caaagttgcc ttgggaagcg agtttattga gttcgccacc aattccaacg gcatctgcac
    15781 cagcagcgaa ccattgaggg atgttgttta ggccgactcc tccggttacc attacggaaa
    15841 cttgtgggat cggtgccttg actgcagaga tatatgctgg actgagagta ctacctggga
    15901 agagtttgat gatttcacta ccggcttcaa gtgcagtcgt gatctctgtg agggtaatac
    15961 agcctggaat gtacggtgtg ctgtagagat tgcacatttt cgcagtttca gcatggaaag
    16021 atggagaaac aacgtaattt gctccagcta gaatggcatc tctagcagtt acggcatcaa
    16081 gcacagtacc tgcaccgata caaacactct gatcgtcctg atacaagtct acaagttcct
    16141 tgatgatttg tcctgcatac tgattggtat aggcgatttc aatagctttg ataccgccct
    16201 tgatacaagc aatcgaggct tgtagtcctt cttcctttgt atttcctcga atgacagcga
    16261 caattttctg tttttttagt tcaataatcg tatctgattt ggtcatgtaa ttctcctaac
    16321 gaatgatatc ttgtgcattt gccagtaaat tttcaatact agttgcggaa gtggagagat
    16381 ggtctcctgg aagagtgcat ttgagagttg cgctcgcaac tgcaaagtca atggtagttt
    16441 ttagggagga atgatggagt agttggtaaa gggcaccaga tataaaggca tccccgctac
    16501 caattcgttg atagactgca gtttttagtt ggacagactc ttcaaatcgt tcttccagag
    16561 cataggcttg atagacattt ttgtcttgct catcactaga tcggagggta tggaaaatgg
    16621 ccttgaaacc ataggcttct tttaaaagtc gcatgcgatt ttccacctct tctaggctag
    16681 cactgtctct tggaaacatc tctagatttt ggtcatcaat catgagagga tcaataccga
    16741 agcaatagtc agtaaaacgt gcaaacttag aaaattcata cttggcttct aggactgaaa
    16801 tcatctttgt tctcagattg agatccattg aaacgacaat tcctcggcgc ttggcttctt
    16861 ccaagagtag gagaaggatc gcacggacct cttgaccgat agctatggtg attccactaa
    16921 aatgaaaatg gctaatcccc tgaaagagag aatccatatc tagcatgttt ggccgaatct
    16981 ggctgatact cgtatgctta cgatcgtaga aaacttcact ttgacgacaa ccaaagccgt
    17041 tctccaaata gtagaggccg attcgatcgc caagccgaca gattgaactg gtatcgattt
    17101 ggtgctgttt caagaatgtg agaaaacgat ctccaatctc gttggcaggg agtgcggtaa
    17161 agactttcgt tgagataccc agggcttgca aattacaagc gatgttaatt tctgatccgc
    17221 caaaataagt cgaactggca acatgatcgc cgatactggt ggcatctaat ggtgagattc
    17281 gaattaatgg ttcgccaaac agtaatattt tcgtcatcca ttagttcctt tctggtttag
    17341 aatagcttta cttggctaat acttctttca aataagcagc gacttcatca tcttggcagt
    17401 tttcaaagaa gtattcttgg aagtatttgc cagagatggt gtctttgagg aagtcttggt
    17461 cgattgtttt aaggatggtc atcaaatcat tgtgggtgat ttgtttcacc tcgtttaaga
    17521 tacgagcgtt gcgttgttca gggattacac gttctcttgg gtagccaccg cccatttctt
    17581 cagcaaataa gcgttcaaac atcaatttga gggtcagttc tgccccccag ccaaatcctt
    17641 tggcataagg gatagacaag gcgttaccac cattgatttg agaataaagg taagcgtcag
    17701 ttgggtccac tgctagacca cagacaacac cagggaagct gtttaaagca agcatagccc
    17761 ctacacccgt accacagccg gtaacaacaa agtcaactgc ctttgtattt aaaaggatgg
    17821 cagccattag tccgttctgc acataagtta attgactttc tccttcttct ccacgcatac
    17881 catagttaaa taattggtag tcttttttat ctgtcgcttc ttttagacta tcgtaaataa
    17941 tgtgattctt gctagcttga ctattttcat tgattaatgc gattttcata agatcttctt
    18001 tctattttta ctcaggttgt tttccgatgt aggctaagat accgccatct acatatagga
    18061 tgtggccatt gacaaaattg ctggcatcac tagcgagaaa gacagcaggg cccatcaaat
    18121 cttcaggatt tccccaacgt gcagcaggtg tttttgcaat gatgaactgg tcaaatgggt
    18181 ggcgagaacc atcttcttgc aactcacgaa gaggtgctgt ttgaggagtg gcaatataac
    18241 ccggtccaat tccgttacat tggatattgg ctccaccgta ttcagacgca atgttgcggg
    18301 tcaacatttt caagccccct ttagcagcag cataagcgct aactgtttca cgtcccagtt
    18361 cgctcatcat cgaacaaata ttgataatct ttccatgccc tttctttatc atagaaggaa
    18421 taactgcctt tgaaacgata aatggtgcgt ttaagtcaat atcgatgacc ttacggaaat
    18481 cagcggcgct catttcgcac attggaactc ggcggataat accagcgtta ttaacgagga
    18541 tgtcaatgac accaacctct tgttcgattt gcttgaccat ggcttggata ccgtcctcgt
    18601 ctgtcacgtc acagacatat ccatgggctt cgatgccaac ttcacgataa gcttcaatcc
    18661 ctttattgac cagatcttga ttgatatcgt taaagacaat agtagcgccg gcttcagcgt
    18721 aggatttggc aatagcaaat ccaattccat aagaagcgcc ggtgatgaga gcaatttttc
    18781 cttttaaaga aaactgctca attgagaatg atgtatttgt catttgatac ttcctttcaa
    18841 atttgttaag acttctctat aaccaaatta tattctagca aaccggtttt gtcaataaat
    18901 aaatattttt atttataaaa agatttgttt tcctgaaaaa cggaatgttt tgaaatttct
    18961 gtttattaaa atggttaaaa agataatgaa agcgctaata tttttttaaa aaaactattg
    19021 acaagataaa aataaaggat tacaatgggg aatataaagt aaaccggtaa acctaaacaa
    19081 gaaaggagaa aagatgaaaa ttgtacttgt agggcatgga cattttgcta cagggattta
    19141 tagttcttta caattgattg caggtaatca agaaaatgtg gaggcgattg actttgtgga
    19201 aggaatgtca gcagatgaac tcaagcaaaa aatcttactt gcaatttcaa atgaagaaga
    19261 agttttaatc ctaagtgatc tcttgggagg atcgccattc aaggtttctt ctaccataat
    19321 gggagaaaat ccagtcaaaa caatgaatgt tctctcgggt ttgaacttag ccatgttaat
    19381 ggaagcagtc tttgctagaa tggctcatag ctttgatgag gttgttaata aatcagtagt
    19441 ggcggcccag ggcggagtcg taaatggtaa agaattgttt tcaacggatg cagaggaaga
    19501 agatttcgaa tcgggtattt aaagggtaaa agaatgataa aaaaggttac gattgaaaaa
    19561 ataaaatcgc ctgagcgctt cttagaagta ccacttctga cgaaagaaga agtcggccag
    19621 gcaatcgata aggttattcg gcagttagaa ctcaaccttg actatttcaa ggaagatttc
    19681 ccgacgccag ctacctttga taatgtctat ccaatcatgg ataacacgga atggaccaat
    19741 ggtttctgga caggagaact gtggttggct tatgaataca gtcaacagga tgcatttaaa
    19801 aacatcgctc ataaaaatgt tctttctttc ctggatcgtg tcaataagag agtagaattg
    19861 gatcaccatg atctcggctt cttgtacaca ccgtcttgta tggctgaata taagataaat
    19921 ggagatggag aggctagaga agcaaccttg aaagctgcag ataagttgat tgaacgctat
    19981 caagaaaaag gtggttttat tcaagcttgg ggagacttgg gcaagaaaga gcattaccgt
    20041 ttgattatcg actgcttgct caatatccaa ctcttattct ttgcttatca agaaacaggc
    20101 gatcaaaaat actacgatat tgcagaaagt catttctatg cttcagctaa taatgtaatc
    20161 cgtgatgacg cttcgtcctt ccacaccttc tattttgatc ctgagacagg tcaacccttt
    20221 aaaggtgtaa cgagacaagg gtatagtgat gattcatgct gggcacgtgg tcaatcatgg
    20281 ggagtctatg gtattccttt gacttatcgt cacttaaaag acgagtcctg ctttgacttg
    20341 tttaagggtg tgaccaatta tttcttgaat cgtctgccaa aagatcatgt gtcctattgg
    20401 gatttgattt ttaatgatgg tagtgctcaa tcacgagatt cttcagcaac agctatcgcc
    20461 gtctgtggga ttcatgaaat gctaaaacat ctcccagagg tggatgctga caaagatatt
    20521 tataaacatg ctatgcatgc catgcttcgt tccttgatcg aacattatgc aaatgatcaa
    20581 tttacccctg gtgggacaag tcttctccac ggtgtgtact catggcattc aggtaaagga
    20641 gtggatgaag gcaatatctg gggtgactac tattacctag aagcccttat ccgtttctac
    20701 aaagactgga acctatattg gtaggaggag aaatatgaca atgccaaata ttattatgac
    20761 ccgtatcgat gaacggttga ttcatggaca aggacaactt tgggtaaaat acctagcttg
    20821 taatacggtc attgttgcca atgacgaagt aagcacggac aagatgcaac aaactctgat
    20881 gaaaacagtt gtgccagact cagttgccat gcgtttcttc cctttgcaaa aggtgattga
    20941 tatcattcac aaggctaatc ctgctcaaac gatctttatc gttgtaaagg atgtaaagga
    21001 cgctttaacc ttggtagaag gtggtgtccc tatcaaagaa atcaatattg ggaacattca
    21061 caatgcccct ggtaaagagc aagtgacacg ctccatcttc ctgggtgaag aggacaaggc
    21121 agccctcaag gaattaagcc aaactcatca agtaacattt aatacgaaaa caactccaac
    21181 aggaaatgat ggagctgttc aagtcaacat tatggactat atttaaaaga ggagatcgtt
    21241 atgtcgatta atgtatttca agcgatttta attggattat ggacagcttt ctgttttagt
    21301 ggaatgctgt taggaattta caccaataga tgtattgttc tgtcatttgg tgtcggaatt
    21361 attctaggtg atctgcctac tgctcttgca atgggagcta ttggtgaatt ggcttatatg
    21421 ggattcggtg ttggtgctgg aggtactgtt ccaccaaacc caatcggacc tggtatcttt
    21481 ggtaccttga tggctatcac tagtgctggt aaagtcagtc cagaagcggc tcttgccctc
    21541 tctactccga ttgctgtggc gattcaattc ttacaaactt tcgcctacac tgtacgtgct
    21601 ggtgcgcctg aaacggcgat gaagcacttg aaaaaccata atttgaagaa attcaagttt
    21661 actctaaatg caacaatttg gttgtttgcc tttattggat ttaccttggg ttgcttgggt
    21721 gccctttcaa tggatacctt gttgaaactc gtagactaca ttccaccggt attacttaca
    21781 ggtttgacag ttgctggtaa aatgctccca gctatcggtt ttgcgatgat cttgtcagtg
    21841 atggctaaga aagagttgat tccctttgtc ttgttgggat atgtttgtgc agcttatcta
    21901 aacatcccaa caattggtat tgcaattgta ggtactatct ttgctttgat tgaattttat
    21961 aacaagccaa aaacagcgaa tcatgtggta gaggaggaag cacacgatga ctggatctaa
    22021 caaattaaca aaacgtgatt atcttaaaac gtctttgcgg gcattctttt gtcaaaatgg
    22081 atttaactat agtaactatc aagggttggg atatgccaat gtgatgtatc ctgctttgaa
    22141 aaaacactat ggagaggatc aggaaggttt ctaccaagcc ttggaagaaa actgtgaatt
    22201 ctataatacc aacccacact tcctgccttt tattaccagc ttgcatcttg taatgttgga
    22261 aaatggccgt ccggcaaaag aaacacgtag catcaagatg gccttgatgg gaccattggc
    22321 aggtattggg gattctcttt ctcaattctg tttagctcca ttgttctcaa ccatcgcagc
    22381 ttcgtttgct caagaaggct tggttgtcgg tccaatcttg ttcttccttg cgatgaatac
    22441 gattttaaca gcgattaaat tgtcaactgg tctgtatgga tacaaactag gaacaactgt
    22501 gattgataaa ctaagcgaac agatggcaac gatttctcgt attgccaata ttatcggtgt
    22561 aaccgtaatt gctggtttgg cagcgacatc tgttaagatt atggtgccga ttacctttgc
    22621 tgcaggggaa gttaaagcag acgctaaaca aagtatcgta agtattcagg gaatgcttga
    22681 taaggttgct ccagctcttc taccagccct atttacactt ttagtttact acttgatcaa
    22741 agaaaagaaa tggacaacat ataaactcgt tattttaaca gttgtcatcg gaattatcgg
    22801 aagctggctt aagattatag cttaatggat acaacattgt tttatggaat agtgattgtc
    22861 ttggcagtga gtcccctttt actgtcaagc tttcattcta ttcgtcagca aaagttgctt
    22921 cgcaaacaga cggagcaacg acaagagtat ttagcttctt taacatctgg tgatgaagtg
    22981 ttgttattgt ctggaattca tggaaaaatc atttctatca aagatgactt ggtctccttg
    23041 cagattgcaa aaggtgtggt catctatgta gaaaaggaaa gtgtaatggg aaagacaaaa
    23101 gaactgcttt ttaagtagtt ctttttctgg taatagataa tgaaagaaga aagaagacaa
    23161 ttttttgaaa gagtcgatgg aaaccaatgt cgtgattata tcttgtcgca ctgttcaaaa
    23221 gactatgaga aagtcaagag ttcccttgaa cgcttgatgg acaatcgttt tatgtttgat
    23281 agtccttggg atatggagcc ttgttcaaaa atccatcaaa tccagccgat ggtatgggat
    23341 caagtatttg aagatgatcc agaatgggct tatatgctca atcgacaaga atatctcttg
    23401 cagtttatga tagggtatgt ggtagaagga gataaggact atattcaaaa gtgcaagttc
    23461 tttctatttg attggattga gcaggtgaga gaattttctc ctcaatcctt gatgactaga
    23521 accttggata cgggtattcg ttcctttact tggttgaaac tactcttgct cctcttgaaa
    23581 tttgacatgc tagaggagaa agaactagag aaaattttgg tcagtctaga aaagcagatt
    23641 gactttatga aaagctacta tcgcgccaag tacaccctta gtaactgggg gattttacaa
    23701 acaattccga tgcttgctat ctattatttc ttttcagata agatggacct agaagaagct
    23761 taccattttg cttcagagga gttgaaacag caaattgaga cacagatttt aggagatgga
    23821 agccagtttg aacagtcgat tctctatcat gtagaggttt ataaagcctt gctggatttg
    23881 tgtctcttgc ttccagactt gcaagatagt taccgagagt tgctggaaaa gatggcgacc
    23941 tatattcaaa tgatgacagg cttagatgga cgaactttgg cttttggtga tagcgattct
    24001 acagaaacga cagaaatttt gagcctgtct gctgtggttt tgaacaagga agaccttctt
    24061 aacggtctgg atgttaaagt cgatttgctt agcctcttgt tcctggggcg agaaaaggtc
    24121 aagcgactgc aggaatttga aaagagagct tggcagccta agtccatgat ctttgaagac
    24181 tctggacatg tctgcattaa ggatgaacat cgttatctat ttttcaaaaa tggtccgcta
    24241 ggaagtgccc atagccatag tgacgagaat agtttttgct tacagtatca aggacaacct
    24301 attttcatag atgctgggcg ttattcttat cgggagatat atgaacgtta tctcttaaag
    24361 agtgcttgga gtcattcgac ctgcattgta gatgggaaag ctccggaaag aatcacggga
    24421 tcctgggaat atgaatacta tcctcactcc ctgttttgtc accataaaga aagggaggga
    24481 gtgcattata ttgaaggggc ttattggtca gcagaacctg atttgcctta tcttcacaag
    24541 agaaaaatcc tcatgttggt agaggatgtc tggctcttgg tggatgacat caggtgtcaa
    24601 ggtcagcatg aggcgttgac tcagtttatc cttgacaagg atgtgaccta tcaagatggg
    24661 aaaatcaatc agttgagact atggagtgaa gttgattttg atttggaaga taccatcatt
    24721 tctcctaaat acaatgagct tgaaagaagt aacaaactca ccaagcgcca attctttgag
    24781 aatcagatgc tggattatac catcattgcg catgagagtt ttgaaatcat ccgtcattct
    24841 gtctaccaga cagatgatcg tgaagtggaa aatgctctgg cttttgaagt gaaaaatgac
    24901 gaaacagaca agctgattct gttattaagc gaggatattt gtgtaggtga aaaattgtgc
    24961 ctcgttgacg gaacaaaaat gcgtggaaaa tgtctagtat atgataaaat aaatgagaga
    25021 atgattcgct tgcagtgcta gaaataggca ttttgaatag tgaatatgtt ataataagta
    25081 ttagtaggag gtgttttaga ttggagaaga aactgaccat aaaagacatt gcggaaatgg
    25141 ctcagacctc gaaaacaacc gtgtcatttt acctaaacgg gaaatatgaa aaaatgtccc
    25201 aagagacacg tgaaaagatt gaaaaagtta ttcatgaaac aaattacaaa ccgagcattg
    25261 ttgcgcgtag cttaaactcc aaacgaacaa aattaatcgg tgttttgatc ggtgatatta
    25321 ccaacagttt ctcaaaccaa attgttaagg gaattgagga tatcgccagc cagaatggct
    25381 accaggtaat gataggaaat agtaattaca gccaagagag tgaggaccgg tatattgaaa
    25441 gcatgcttct cttgggagta gacggcttta ttattcagcc gacctctaat ttccgaaaat
    25501 attctcgtat catcgatgag aaaaagaaga aaatggtctt ttttgatagt cagctctatg
    25561 aacaccggac tagctgggtt aaaaccaata actatgatgc cgtttatgac atgacccagt
    25621 cctgtatcga aaaaggttat gagcattttc tcttgattac agcggatacg agtcgtttga
    25681 gtactcggat tgagcgggca agtggttttg tggatgcttt aacagatgct aatatgcgtc
    25741 acgccagtct aaccattgaa gataagcata cgaatttgga acaaattaag gaatttttac
    25801 aaaaagaaat cgatcccgat gaaaaaactc tggtatttat ccctaactgt tgggccctac
    25861 ctctagtctt taccgttatc aaagagttga attataactt gccacaagtt gggttgattg
    25921 gttttgacaa tacggagtgg acttgctttt cttctccaag tgtttcgacg ctggttcagc
    25981 cctcctttga ggaaggacaa caggctacaa agattttgat tgatcagatt gaaggccgta
    26041 atcaagaaga aaggcaacaa gtcttggatt gtagtgtgaa ttggaaagag tcgactttct
    26101 aaaatgaagg aaaatgactt gcaatctctg ttaagaaata aaataatccc acctagaaca
    26161 agctaggtgg gattatttgc ttatgaaatg agaaattatg ggagcaagct cctaaatcaa
    26221 ctgtttttga tctacttctt taactacttg ataaaagtta tagaagtagg ccaaacttga
    26281 aatgatggtt acgactagga atattgaaaa tttccattgg acagggttgg ttaaaagttg
    26341 tggaaaggat atgaggagaa agaagagggc tgcgttgagg acaggtatcc gttttgattg
    26401 tattttctca agtcctttat tgagcgcagg aagaaagagg agtaggagta gtaaaactgt
    26461 atgagaaaca gctcctgaaa taagggcgaa gaaaaggaaa atactgataa aaacatgaat
    26521 gttcagtagt ctagctagtg atttcataag gcacctccta atcctggtct tttttagctc
    26581 ttgcaatacg aagtgagtcg acaatatgta tcatcactcc gaaaaagaaa gctcccagta
    26641 tagttttaaa aatatgtttt gtatttagaa gagaactgat aaaatttgga ttttcacttg
    26701 ttagggtatc aatgagtgga attataaaaa atatcactgt tccataaatc gaacctgctt
    26761 tcagaccagg ataacgtaac tgtttctttt cttttttcat gagtttcctc ctaatcctca
    26821 tcttgatttt tcttagtttt tgcaatgcga cgggagatga ggaactgtat gctcgctccg
    26881 aagaaaatag aaccgagaat acttgataca ccatttctta tagtgagaag agaatgaaaa
    26941 tagtcctgac cttcatctat gagtatactg agaagaggag ttataaaaaa catccataga
    27001 ccaaagaaca aacctgcttt cagacctggg tagtgtagtt gcttgctttc tttctcattc
    27061 agcatatctg gttcaatgac tgtgatgcct gtttttttca tttggtaggt gacatagcca
    27121 gcagcgatga gggcaatcac taaaatcaga ggaggataga ttagagccac ttcttgaggg
    27181 tatttatagg ctagaaggag tggaataaga tttccgaaaa tcatcagata aaagaggacg
    27241 ataaagactt ggttcccaat actatcggcc tcacgccgtt tgtattcgtc aaggggacca
    27301 gaaataccgt atgtgcgttt gatcagtttt tcagtgaagg tttctttttt catgagtttg
    27361 ctcctttttt aaaaatcttc ctcccaaaag agactgttga ggtcagtttg gaggctgcgg
    27421 gcgagattga gacagagttc caaggttgga ttgtacttgt cgttttcaat catattgata
    27481 gtctgtctcg agacaccgat atccttggcg agttcgagct gggaaatacc caattccttg
    27541 cgaaattctt tcacacgatt catctggtct cctttctgat ttatgtcgta tatatttgac
    27601 tatattatag tcttttaaac ataaagtgtc aagtatattt gacatatttt ttgaagaaat
    27661 agtagtctcc ttgtcctatt tgtctgacaa gtgcaagctg gtcggatttg tggtaaaata
    27721 gataagatat gacaaaagaa tttcatcatg taacggtctt actccacgaa acgattgata
    27781 tgcttgacgt aaaacctgac ggtatctacg ttgatgcgac tttgggtgga gcaggccata
    27841 gcgagtattt attaagtaaa ttaagtgaaa aaggccatct ctatgccttt gaccaggatc
    27901 agaatgccat tgacaatgcg caaaaacgct tggcacctta cattgagaag ggaatggtga
    27961 cctttatcaa ggataacttc cgtcatttac aggcacgttt gcgcgaagct ggtgttcagg
    28021 aaattgatgg aatttgttat gacttgggag tgtctagtcc tcaattggac cagcgtgagc
    28081 gtggtttttc ttataaaaag gatgcgccac tggacatgcg gatgaatcag gatgctagtc
    28141 tgacagccta tgaagtggtt aatcactatg actatcatga tttggttcgt attttcttca
    28201 aatacggtga ggataaattc tctaaacaga ttgcgcgtaa gattgagcaa gcgcgtgaag
    28261 tgaagccgat tgagacaacg actgagttag cagagattat caagttggtc aaacctgcca
    28321 aggaactcaa gaagaagggt catcctgcta agcagatttt ccaggctatt cgaattgaag
    28381 tcaatgatga actgggagcg gcagatgagt ccatccagca ggctatggat atgttggctc
    28441 tggatggtag aatttcagtg attacctttc attccttaga agaccgcttg accaagcaat
    28501 tgttcaagga agcttcaaca gttgaagttc caaaaggctt gcctttcatc ccagatgatc
    28561 tcaagcccaa gatggaattg gtgtcccgta agccaatctt gccaagtgcg gaagagttag
    28621 aagccaataa ccgctcgcac tcagccaagt tgcgcgtggc cagaaaaatt cacaagtaag
    28681 agggaaaaag atggcagaaa aaatggaaaa aacaggtcaa atactacaga tgcaacttaa
    28741 acggttttcg cgtgtggaaa aagcttttta cttttccatt gctgtaacca ctcttattgt
    28801 agccattagt attattttta tgcagaccaa gctcttgcaa gtgcagaatg atttgacaaa
    28861 aatcaatgcg cagatagagg aaaagaagac cgaattggac gatgccaagc aagaggtcaa
    28921 tgaactatta cgtgcagaac gtttgaaaga aattgccaat tcacacgatt tgcaattaaa
    28981 caatgaaaat attagaatag cggagtaaga tatgaagtgg acaaaaagag taatccgtta
    29041 tgcgaccaaa aatcggaaat cgccggctga aaacagacgc agagttggaa aaagtctgag
    29101 tttattatct gtctttgttt ttgccatttt tttagtcaat tttgcggtca ttattgggac
    29161 aggcactcgc tttggaacag atttagcgaa ggaagctaag aaggttcatc aaaccacccg
    29221 tacagttcct gccaaacgtg ggactattta tgaccgaaat ggagtcccga ttgctgagga
    29281 tgcaacctcc tataatgtct atgcggtcat tgatgagaac tataagtcag caacgggtaa
    29341 gattctttac gtagaaaaaa cacaatttaa caaggttgca gaggtctttc ataagtatct
    29401 ggacatggaa gaatcctatg taagagagca actctcgcaa cctaatctca agcaagtttc
    29461 ctttggagca aagggaaatg ggattaccta tgccaatatg atgtctatca aaaaagaatt
    29521 ggaagctgca gaggtcaagg ggattgattt tacaaccagt cccaatcgta gttacccaaa
    29581 cggacaattt gcttctagtt ttatcggcct agctcagctc catgaaaatg aagatggaag
    29641 caagagcttg ctgggaacct ctggaatgga gagttccttg aacagtattc ttgcagggac
    29701 agacggcatt attacctatg aaaaggatcg tctgggtaat attgtacccg gaacagaaca
    29761 agtttcccaa cgaacgatgg acggtaagga tgtttataca accatttcca gccccctcca
    29821 gtcctttatg gaaacccaga tggattcttt tcaagagaag gtaaaaggaa agtacatgac
    29881 agcgactttg gtcagtgcta aaacagggga aattctggca acaacgcaac gaccgacctt
    29941 tgatgcagat acaaaagaag gcattacaga ggactttgtt tggcgtgata tcctttacca
    30001 aagtaactat gagccaggtt ccactatgaa agtgatgatg ttggctgctg ctattgataa
    30061 taataccttt ccaggaggag aagtctttaa tagtagtgag ttaaaaattg cagatgccac
    30121 gattcgagat tgggacgtta atgaaggatt gactggtggc agaatgatga ctttttctca
    30181 aggttttgca cactcaagta acgttgggat gaccctcctt gagcaaaaga tgggagatgc
    30241 tacctggctt gattatctta atcgttttaa gtttggagtt ccgacccgtt tcggtttgac
    30301 ggatgagtat gctggtcagc ttcctgcgga taatattgtc aacattgcgc aaagctcatt
    30361 tggacaaggg atttcagtga cccagacgca aatgattcgt gcctttacag ctattgctaa
    30421 tgacggtgtc atgctggagc ctaaatttat tagtgccgtt tatgatccaa atgatcaaac
    30481 tgctcggaaa tctcaaaaag aaattgtggg aaatcctgtt tctaaagatg cagctagtct
    30541 aactcggact aacatggttt tggtagggac ggatccggtt tatggaacca tgtataacca
    30601 cagcacaggc aagccaactg taactgttcc tgggcaaaat gtagccctca agtctggtac
    30661 ggctcagatt gctgacgaga aaaatggtgg ttatctagtc gggttaaccg actatatttt
    30721 ctcggctgta tcgatgagtc cggctgaaaa tcctgatttt atcttgtatg tgacggtcca
    30781 acaacctgaa cattattcag gtattcagtt gggagaattt gccaatccta tcttggagcg
    30841 ggcttcagct atgaaagact ctctcaatct tcaaacaaca gctaaagctt tggagcaagt
    30901 aagtcaacaa agtccttatc ctatgcctag tgtcaaggat atttcacctg gtgatttagc
    30961 agaagaattg cgtcgcaatc ttgtacaacc catcgttgtg ggaacaggaa cgaagattaa
    31021 aaacagttct gctgaagaag ggaagaatct tgccccgaat cagcaagtcc ttatcttatc
    31081 tgataaagta gaggaagttc cagatatgta tggttggaca aaggagactg ctgagaccct
    31141 tgctaagtgg ctcaatatag aacttgaatt tcaaggttcg ggctctactg tgcagaagca
    31201 agatgttcgt gctaacacag ctatcaagga cattaaaaaa attacattaa ctttaggaga
    31261 ctaatatgtt tatttccatc agtgctggaa ttgtgacatt tttactaact ttagtaggaa
    31321 ttccggcctt tatccaattt tatagaaagg cgcaaattac aggccagcag atgcatgagg
    31381 atgtcaaaca gcatcaggca aaagctggga ctcctacaat gggaggtttg gttttcttga
    31441 ttacttctgt tttggttgct ttctttttcg ccctatttag tagccaattc agcaataata
    31501 tgggaatgat tttgttcatc ttggtcttgt atggcttggt cggattttta gatgactttc
    31561 tcaaggtctt tcgtaaaatc aatgaggggc ttaatcctaa gcaaaaatta gctcttcagc
    31621 ttctaggtgg agttatcttc tatcttttct atgagcgcgg tggcgatatg ctttctgtct
    31681 ttggttatca agtgcatcta gggattttct atattgtctt cgctcttttc tggctagtcg
    31741 gtttttcaaa cgcagtaaac ttgacagacg gtgttgacgg tttagctagt atttccgttg
    31801 tgattagttt gtctgcctat ggagttattg cctatgtgca aggtcagatg gatattcttc
    31861 tagtgattct tgccatgatt ggtggtttgc tcagtttttt catctttaac cataagcctg
    31921 ctaaggtctt tatgggtgat gtgggaagtt tggccctagg tgggatgctg gcagctatct
    31981 ctatggctct ccaccaagaa tggactctct tgattatcgg aattgtatat gtttttgaaa
    32041 caacttctgt tatgatgcaa gtcagttatt tcaaactgac aggtggtaaa cgtattttcc
    32101 gtatgacgcc tgtacatcac cattttgagc ttgggggatt gtctggtaaa ggaaatcctt
    32161 ggagcgagtg gaaggttgac ttcttctttt ggggagttgg gcttctagca agtctcctga
    32221 cccttgcaat tttgtatttg atgtaagaat ggcaccctga tgtttcaggg tgtttttgtg
    32281 tttaaataca caatgaaaat caaagaacaa actagaaagc taactttagg ctgctcaaaa
    32341 tatagtagat tgaaactaga atagtacacc tctacttcta aaacattttt agaaatcgat
    32401 ttgactgtcc tgaacgattt atcctgttct tatttcattt tactatacag ttttgagatg
    32461 gttgatagaa ctgacgaagt cagctcaaaa cactgttttg aggttgtaga caaggcgaag
    32521 ctgatgtggt ttgaagaggt tttcgaagag tgtaaaaaaa tattggtcag ttaaagtcaa
    32581 aactcttgac cttttctgac caatgtagta tattatgaac gtaaggtaaa tgaaagcctt
    32641 actagaacac ttatttaaag taaaatagaa agaggtgagt ctatgtttca tctagcaatc
    32701 ttcagaggta aagatagtct actcctgctt gaaaaagaaa aaccagaaat agtacgtagg
    32761 gtagcgatct agctagtcta aattttttaa aacaatggtc aaagatagtc aatatcagta
    32821 atcataacta agtaaacaaa aagaggtaaa gaatatgaat aacaacttta ataattttaa
    32881 taacatggat gatttattta accaattgat gggtggtatg cgaggatata gttctgaaaa
    32941 tcgccgttac ttaattaatg gacgcgaagt cacacctgag gaatttgctc actatcgtgc
    33001 gactggtcaa ttaccaggaa atgcagaaac tgatgtgcaa atgccacaac aggcatcagg
    33061 tatgaaacaa gacggtgtcc ttgcaaaact aggtcgaaac ttaacagcag aagcgcgtga
    33121 gggcaagttg gatcctgtta tcggacgaaa caaggaaatt caagaaacat ctgaaatcct
    33181 ctcacgccgc accaagaaca atcctgtttt ggtcggagat gcaggtgttg gtaagacagc
    33241 agttgtcgaa ggtctagcgc aagccattgt gaacggagat gttcctgctg ctatcaagaa
    33301 caaggaaatt atttccattg atatctcagg tcttgaggct ggtactcaat accgtggtag
    33361 ctttgaagaa aatgtccaaa acttagtcaa tgaagtgaaa gaagcaggga atattatcct
    33421 cttctttgat gaaattcacc aaattcttgg tgctggtagc actggtggag acagtggttc
    33481 taaaggactt gcggatattc tcaagccagc tctctctcgt ggagaattga cagtgattgg
    33541 ggcaacaact caagacgaat accgtaacac catcttgaag aatgctgctc ttgctcgtcg
    33601 tttcaacgaa gtgaaggtca atgctccttc agcagagaat acttttaaaa ttcttcaagg
    33661 cattcgtgac ctctatcaac aacaccacaa tgtcatcttg ccagacgaag tcttgaaagc
    33721 agcggtggat tattctgttc aatacattcc tcaacgtagc ttgccagata aggctattga
    33781 ccttgtcgat gtaacggctg ctcacttggc ggctcaacat ccagtaacag atgtgcatgc
    33841 tgttgaacga gaaatcgaaa cggaaaaaga caagcaagaa aaagcagttg aagcagaaga
    33901 ttttgaagca gctctaaact ataaaacacg cattgcagaa ttggaaagga aaatcgaaaa
    33961 ccacacagaa gatatgaaag tgactgcaag tgtcaacgat gtggctgaat ctgtggaacg
    34021 aatgacaggt atcccagtat cgcaaatggg agcttcagat atcgaacgtt tgaaagatat
    34081 ggctcatcgc ttgcaagaaa aggtgattgg tcaagataag gccgtagaag ttgtagctcg
    34141 tgctatccgt cgtaaccgtg ctggttttga tgaaggaaat cgcccaatcg gcagcttcct
    34201 ctttgtaggg tctactgggg ttggtaagac ggagcttgct aagcaattgg cactcgatat
    34261 gtttggaacc caggatgcga ttatccgttt ggatatgtct gaatacagtg accgcacagc
    34321 tgtttctaag ctaattggta caacagcagg ctatgtgggt tatgatgaca atagcaatac
    34381 cttaacagaa cgtgttcgtc gcaatccata ctctatcatt ctcttggatg aaattgaaaa
    34441 ggctgatcct caagttatta cccttctcct ccaagttcta gatgatggtc gtttgacaga
    34501 tggtcaagga aatacagtaa acttcaagaa tactgtcgtt attgcgacct caaatgctgg
    34561 atttggctat gaagccaact tgacagaaga tgcggataaa ccagaattga tggaccgttt
    34621 gaaacccttc ttccgtccag aattcctcaa ccgctttaat gcagtcatcg agttctcaca
    34681 cttgactaag gaagaccttt ctaagattgt agatttgatg ttggctgaag ttaaccaaac
    34741 cttggctaag aaagacattg acttggtagt tagtcaagcg gctaaagatt atatcacaga
    34801 agaaggttac gacgaagtca tgggggttcg tcctctccgt cgcgtggttg aacaagaaat
    34861 tcgtgataag gtgacagact tccacttgga tcatttagat gctaaacatc tggaagcaga
    34921 tatggaagat ggcgttttgg ttattcgtga gaaagcctaa gatagaattt tgaggataaa
    34981 aaagaaggag ccagctgaaa aaaactggtt cctttttagg tacgacaggc atgtcgtata
    35041 gtagaagtgt attattccag tttcaatata ctatagtagc tcagaagtcg gtacttaaac
    35101 gtgctatatc aaaaccagtc cttgaaaaac gtggactggt ttcgtgtttg gattattacc
    35161 ttgaacgaca tgcgttaaaa gttagttgaa ccgccgtatg ccgaacggta cgtacggtgg
    35221 tgtgagaggg gctagagatt atcccctact cgattgtcta tagctatagg ggtaaagtta
    35281 ttagagaggt tgctagttta tagagacatc ttgatttgta aaaagttaaa ttttagacaa
    35341 ttatcccctt taaaaaatct attaaaccat agctagttga agtaaatttt tatagaacat
    35401 aattttattt atcaagacat tgtagagttg aggcaaattg aaaaagaaag tttaaaagtt
    35461 gataataagt caataagaaa gctattaatt ctaacgagat tatttgatag taatttgttt
    35521 tttcagctac tattcggaca atgttattat aataaacaca ggagagaaca ccagaaggta
    35581 gggacatcag aagaaatagt tcaggatata gttaacataa tcatcaaaga agctcctaga
    35641 ctcgctaatg ttaatttgga aacatattat ccagatgaat atatgtcaaa tacattgaag
    35701 caattactac tttttagaga ggagttcata aaaaatattt tgaatgggat tgatgtggat
    35761 gaaacagtag taatagaaaa tgattttgta gaagagttgg agaacttttt aaaagagaat
    35821 gatttgctag atttttcaaa tagcatattt tttcagttat ctggagataa agtaatagtg
    35881 aataatattt atccaggata tttagcatat tttaataggt tccttacatt ttatccgaaa
    35941 atattcgcta ttaaagaagt tggagaatat attgactttt taaattttga aaagagaatt
    36001 gcggatatgt tttattgttg gggatttaat gcaaattcta gagtgttgac agctgaaaaa
    36061 ataattgaaa tcccaaatca ccaaatcaat gctaagtaca taaaaaaagt tataaaaatg
    36121 agtgaactct tgtttggtgt tgatagtaat aacagaattc ggttgcttaa caatagaagg
    36181 gaattgataa aaactatttt ccaaggttct gtaattaagt cagcaattcc tgctctagct
    36241 gctactttgg atacaatcag taacagtgga tcatttcaaa tttctttatc aaagcagata
    36301 attaataatt tagtattaag tggtaaagat aaagttacaa ttcctaggat agagttagat
    36361 aatgttgttc tttcaagaca gaagattatt gtatcagttt cgtatataaa tgattttttg
    36421 gatttgagat ttccagataa aatagaatac attttaaatt ttttagaagg atctggtttc
    36481 aatactaaag taatggtcta ctttgggaaa attgtagaag aagataagaa ctattttgtt
    36541 aatcttgaaa aacctcagta ttttgatttt accagtatac ttttcaataa gttattcttt
    36601 aaagaattaa acaagtttga ttacatggtt attgaagaac tcattccaaa tcttgatgaa
    36661 gatgtaatga tgacagagta tataaaagag tatactgaat aggagcaatc tattatgatt
    36721 ttaagtaaag tacgttgtta catatataat tctaaaatta gaggtaaagt tctgtatgaa
    36781 ttatatgaat ttataaatga aaataagcaa ttgatggacg caattaattc aattaaagtt
    36841 gacagtagta atggttttag tattcaaata ttacatttag gagaacagca aacaactgtc
    36901 ttattaacag atttttttac taaaacttta gacttgttta aggaatttag ggttacaaat
    36961 aagagtactc ttgagcaggt gaaaaatcaa attagcatac taaattcttc tggtccaaaa
    37021 atggatttaa c
//
LOCUS       DAVAZT010000019        34347 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVAZT010000019 DAVAZT010000000
VERSION     DAVAZT010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34347
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.019"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..4786
                     /locus_tag="VQT45_000855"
     CDS             <1..4786
                     /locus_tag="VQT45_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2359203.1"
                     /translation="QGERGLTGAKGEKGDQGERGLTGAQGEKGDRGERGLTGAKGEKG
                     AQGQAGRDGVTPTVTVKDNKNDGTHTITINDGRGNVTSTVVRDGFDGASPLVATQRND
                     ADKTTTVIFYYDKNGNNELDASDKKLKEVVIADGAKGEKGDKGEQGLQGRDGEQGPKG
                     EDGKTPTVKVTDGQDGTHTITINDGKGGITTTVVRDGFDGASPLVSTHRNEADKTTTV
                     IFYYDLNDNNQFDEGDTKLKEVVIADGKQGPKGDKGDNGKDGFTPEVTVTDNNNGTHT
                     ITITQPDNRPSLTTIVKNGEDGKTPKVKAERDDAKKQTTLTFYIDKDGDGSYTAGKDE
                     LVQTTVVKDGQDGAAGASGRDGKEVLNGKVDPTTEGKDGDTFVNTQTGDVFVKKGNTW
                     EPAGNIKGPKGDKGADGAKGEKGAQGERGLTGAQGVKGEKGDQGERGLTGSKGEKGDQ
                     GERGLTGAQGAKGDKGEQGLQGRDGAQGPKGADGQRGPAGPQGPKGEQGNPGTPGKDG
                     KSLIAVKNGTETKVYVEDPARPGQPLNPNQPLATITDGRNGTNGQSPTITATRSVQNG
                     KNGVLVTITPVGGRPQTTFVEDGQKGADGKTPTVTITEGQNGTHTLTVHNPGSPDVTT
                     TIRDGATGQAGRDGKDVLNGKVNPQPNQGKNGDKYINTETGDVYVKNNGNWDKEGNIK
                     GPKGDKGADGAKGEKGDQGERGLTGAQGAKGADGAVGRDGRDGKDVLNGKANPEAHQG
                     KDGDKYVNTETGDVFVKNNGNWDKEGNIKGPKGDKGERGEDGKTPEVTVTPGKDGHST
                     DITFTVPGKDPVTVNVKDGENGLNGKTPKVDLLRVQGKNGNPSHTIVTFYTDENNDGK
                     YTPGTDELLGSEMIKDGAKGADGRDGKSLLTVKDGKETKVYQEDPANPGQPLNPEKPL
                     AVIRDGVDGKSPTVTAVRKDEAGHKGVEITVDNHDGSQPTTVFVQDGAKGETGATGQD
                     GQTPTITTQRGQDGQSTVVTITTSGKDPVTFTVKDGKNGKDGRAPKIKVEDITSPSRI
                     RRDTDAAATPTRNGIRVTVYDDVNDNGVYDEGVDKVLNSKDIYNGIDGRDGSAPTITT
                     KDNGDGTHTITVQNPDGSESTTVVKDGKDGKTANITTTENPDGSHTITVTNPDGSTKE
                     TVVKNGKDGKTPKVEVTDNNDGTHTVKVTDGDGNVTNAIIKDGKDGKAATATTTENPD
                     GSHTVTITNPDGTKNEFVVKNGRDGVDGRTPTASVRDNGDGSHTIVITNPEGVTTETT
                     VRDGKSPKVTITDEQNGTHKISVLNGDGTTTTTTVRDGREPKLEVIDNNDGSHTIKVT
                     GADGKGTTTTIFDGKSPKANIVDNGDGTHTLTIVDSDGREYKSIIKDGKDGKDSVSPT
                     VTVKNNNDGTHVVTITNPDGSKTEMVIKDGKDGKSPKVSVEDNGDGSHTITIINSDGT
                     VTKTVIKDGRDGRDGRDGKDGKDGKDGKCGCQDKPVTPSNDKPVPPTPNVPTPEVPVK
                     PVPAQPTPNVPTPEVPVQPTPAVPTPEVPVKPVPAVPEQPVVPTPAQPATPVNANPVA
                     PTTGKENRGDKLPETGSQSDYISVLLGSGILLSLYVGRRKEA"
     gene            complement(5023..5571)
                     /locus_tag="VQT45_000856"
     CDS             complement(5023..5571)
                     /locus_tag="VQT45_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET2359204.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            5892..6380
                     /locus_tag="VQT45_000857"
     CDS             5892..6380
                     /locus_tag="VQT45_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HET2359205.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            6377..7564
                     /locus_tag="VQT45_000858"
     CDS             6377..7564
                     /locus_tag="VQT45_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2359206.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            7557..7922
                     /locus_tag="VQT45_000859"
     CDS             7557..7922
                     /locus_tag="VQT45_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2359207.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            7938..9284
                     /gene="asnS"
                     /locus_tag="VQT45_000860"
     CDS             7938..9284
                     /gene="asnS"
                     /locus_tag="VQT45_000860"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HET2359208.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            9437..9727
                     /locus_tag="VQT45_000861"
     CDS             9437..9727
                     /locus_tag="VQT45_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HET2359209.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            9739..10209
                     /gene="ssbA"
                     /locus_tag="VQT45_000862"
     CDS             9739..10209
                     /gene="ssbA"
                     /locus_tag="VQT45_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HET2359210.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            10241..10480
                     /locus_tag="VQT45_000863"
     CDS             10241..10480
                     /locus_tag="VQT45_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HET2359211.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            10775..12175
                     /locus_tag="VQT45_000864"
     CDS             10775..12175
                     /locus_tag="VQT45_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HET2359212.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSYVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDVIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            12177..12536
                     /locus_tag="VQT45_000865"
     CDS             12177..12536
                     /locus_tag="VQT45_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HET2359213.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            12590..13339
                     /locus_tag="VQT45_000866"
     CDS             12590..13339
                     /locus_tag="VQT45_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HET2359214.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICHSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            13329..13628
                     /locus_tag="VQT45_000867"
     CDS             13329..13628
                     /locus_tag="VQT45_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HET2359215.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALFKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            13699..14634
                     /locus_tag="VQT45_000868"
     CDS             13699..14634
                     /locus_tag="VQT45_000868"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HET2359216.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            14721..15233
                     /locus_tag="VQT45_000869"
     CDS             14721..15233
                     /locus_tag="VQT45_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HET2359217.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGAVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            15270..15865
                     /locus_tag="VQT45_000870"
                     /pseudo
     CDS             15270..15865
                     /locus_tag="VQT45_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            15966..16160
                     /locus_tag="VQT45_000871"
     CDS             15966..16160
                     /locus_tag="VQT45_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET2359218.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(16206..17651)
                     /locus_tag="VQT45_000872"
     CDS             complement(16206..17651)
                     /locus_tag="VQT45_000872"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HET2359219.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVDIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTATYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVHRVYGLTFDVGVFLNITPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            17757..19379
                     /locus_tag="VQT45_000873"
     CDS             17757..19379
                     /locus_tag="VQT45_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET2359220.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            19583..21541
                     /locus_tag="VQT45_000874"
     CDS             19583..21541
                     /locus_tag="VQT45_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2359221.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGFLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFATAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            21713..22648
                     /locus_tag="VQT45_000875"
     CDS             21713..22648
                     /locus_tag="VQT45_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2359222.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILLLSNISEKYSRRLQEEIGFLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERV
                     QNNSLKSDRVTSFETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLL
                     NPISNIANFVTVYSRSKGSSVALENLLAVPKEKFE"
     gene            22673..23325
                     /locus_tag="VQT45_000876"
                     /pseudo
     CDS             22673..23325
                     /locus_tag="VQT45_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            23483..24577
                     /locus_tag="VQT45_000877"
     CDS             23483..24577
                     /locus_tag="VQT45_000877"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET2359223.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            24585..25751
                     /locus_tag="VQT45_000878"
     CDS             24585..25751
                     /locus_tag="VQT45_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2359224.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEIQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            25844..28942
                     /locus_tag="VQT45_000879"
     CDS             25844..28942
                     /locus_tag="VQT45_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2359225.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLNRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLQASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            28990..29607
                     /locus_tag="VQT45_000880"
     CDS             28990..29607
                     /locus_tag="VQT45_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET2359226.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            29617..30951
                     /locus_tag="VQT45_000881"
     CDS             29617..30951
                     /locus_tag="VQT45_000881"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HET2359227.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            30961..31425
                     /locus_tag="VQT45_000882"
     CDS             30961..31425
                     /locus_tag="VQT45_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2359228.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     DLDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            31422..31916
                     /locus_tag="VQT45_000883"
     CDS             31422..31916
                     /locus_tag="VQT45_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2359229.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            31997..33646
                     /gene="mltG"
                     /locus_tag="VQT45_000884"
     CDS             31997..33646
                     /gene="mltG"
                     /locus_tag="VQT45_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HET2359230.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMTDSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDIIS
                     DTSRRSRREGAKPVNPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPIDA
                     NSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQKSM
                     STEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAEAFLA
                     KVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDEML
                     AAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDMPL
                     QSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIESSI
                     NQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            33717..34199
                     /gene="greA"
                     /locus_tag="VQT45_000885"
     CDS             33717..34199
                     /gene="greA"
                     /locus_tag="VQT45_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HET2359231.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
BASE COUNT        10714 a         6374 c         7776 g         9483 t
ORIGIN      
        1 ccaaggtgaa cgcggtttaa ctggagctaa aggtgaaaaa ggggaccaag gtgaacgcgg
       61 tctcactgga gcccaaggtg aaaaaggaga ccgaggcgaa cgtggtttaa ctggagctaa
      121 aggtgaaaaa ggagcccaag gtcaggcagg tcgtgacggt gtaactccaa ccgtaaccgt
      181 taaagataat aaaaatgacg gcactcatac tatcactatt aacgacggta gaggtaatgt
      241 tacaagtact gttgtaagag atggtttcga tggcgcaagt ccattagttg cgactcaacg
      301 aaatgacgca gataagacaa caactgttat cttctattac gataaaaatg gaaacaatga
      361 attagatgct tctgataaga aattaaaaga agttgtaatt gcagatggtg ctaaaggtga
      421 aaaaggggac aaaggtgaac aaggtcttca agggcgtgat ggtgaacaag gaccaaaagg
      481 agaagatggg aaaaccccaa cagttaaagt aactgatggt caagatggaa cgcatacaat
      541 tacaattaac gatggtaaag gtggtataac tactacagta gtaagagatg gatttgatgg
      601 tgcaagccct cttgtttcta ctcatagaaa tgaagcagat aaaacaacaa ctgttatttt
      661 ctattatgat ctaaatgata ataatcaatt tgatgaagga gatacaaaac ttaaagaagt
      721 tgttatcgca gatggaaaac aaggaccaaa aggtgacaaa ggtgataacg gaaaagatgg
      781 attcacacca gaagtaacag ttacagataa caataacgga acacacacca tcacaatcac
      841 acaaccagac aacagaccat cattaacaac aatcgttaaa aacggtgaag atggaaaaac
      901 accaaaagtc aaagcagaac gagatgatgc gaagaaacaa acaacattaa cattctacat
      961 tgacaaagat ggagatggaa gttacacagc aggaaaagac gagttagttc aaacaacagt
     1021 agttaaagac ggacaagacg gagctgcagg agcatctgga cgtgatggaa aagaagtatt
     1081 aaacggaaaa gtagacccaa caacagaagg taaagatgga gacacattcg taaatacaca
     1141 aacaggagat gtattcgtta agaaaggtaa cacttgggaa ccagcaggaa acatcaaagg
     1201 accgaaaggt gacaaaggtg cagatggtgc caagggtgaa aaaggagccc aaggagaacg
     1261 cggcctgact ggagcgcaag gtgtcaaggg tgaaaaggga gatcagggtg aacgcggtct
     1321 aactggatct aaaggtgaaa aaggagacca aggtgaacgc ggtttaactg gagcgcaagg
     1381 tgccaaaggt gacaaaggtg aacaaggtct tcaaggtcgt gatggagctc aaggaccaaa
     1441 aggcgcagat ggacaaagag gaccagcggg accacaagga ccaaaaggag aacaaggtaa
     1501 tccaggaact ccaggtaaag atggaaaatc tctaattgct gttaaaaatg gaactgaaac
     1561 aaaagtctat gtagaggatc cggctagacc aggacaacca cttaatccaa accaaccatt
     1621 agcaactatc actgatggaa gaaacggtac taatggacaa tcaccaacaa ttacagcgac
     1681 acgaagtgtg caaaatggca aaaatggtgt attagtaaca attacaccag taggaggtcg
     1741 tccacaaaca acatttgtag aggatggaca aaagggtgct gatgggaaaa ccccaacagt
     1801 aacaataact gaggggcaaa acggcacaca tacattaacg gttcataatc caggaagtcc
     1861 agatgtgaca actacgatcc gtgatggagc tacaggacaa gcaggtcgtg atggtaaaga
     1921 tgtattaaac ggaaaagtaa atccacaacc aaaccaaggt aaaaatggag ataaatatat
     1981 taataccgaa accggtgatg tctatgttaa aaacaatgga aactgggata aagaaggcaa
     2041 catcaaaggc cctaaagggg acaaaggtgc agatggtgct aaaggcgaaa aaggagacca
     2101 aggcgaacgc ggcctaactg gagcgcaagg agctaaaggt gcggatggcg cagtaggtcg
     2161 tgatggacgt gacggtaaag acgtgttgaa cggcaaagct aacccagaag cacatcaagg
     2221 taaagacggc gataaatacg ttaatacaga aacaggcgac gtcttcgtta agaataacgg
     2281 caactgggat aaagagggca acatcaaagg ccctaagggt gacaaaggtg aacgcggaga
     2341 agatggtaag actccagaag taactgtaac tccaggtaaa gatggccata gtactgacat
     2401 tacattcact gttccaggta aagatccagt tacagtaaat gttaaggacg gagaaaatgg
     2461 tctgaacggt aaaactccaa aagttgattt acttcgtgtc caaggaaaaa acggaaatcc
     2521 atctcataca attgtgacat tctatacaga tgaaaacaat gacggcaaat atacaccagg
     2581 aactgatgaa cttctaggtt cagaaatgat taaagatggt gctaaaggcg cggacggacg
     2641 agatggtaaa tcattgctta ctgtcaagga tggtaaagaa actaaagttt accaagaaga
     2701 tccagctaac ccaggacaac cattaaatcc agaaaaacca cttgcggtaa ttagagatgg
     2761 agtagatgga aaatcaccta cagttacagc tgttcgtaaa gatgaagcag ggcataaagg
     2821 tgtagaaatc actgttgata accatgatgg ttcacaacca actacagtct ttgttcaaga
     2881 tggtgctaag ggagaaactg gtgcaaccgg tcaggatgga caaactccta caatcactac
     2941 tcaacgtgga caagatggcc aaagcactgt tgtaactatc acaacatcag gtaaagatcc
     3001 agtaaccttc actgtaaaag atggtaagaa tggtaaagat ggccgtgcac cgaaaatcaa
     3061 agtagaagat attacttcac cttcaagaat tagacgcgat acagatgctg ctgcaactcc
     3121 aacgcgtaac ggtatccgtg ttacagttta tgatgatgtt aatgacaatg gggtatacga
     3181 cgaaggtgtc gataaagtat taaatagtaa agatatttat aacggtatag atggacgtga
     3241 tggttcagct ccaactatta ctacaaaaga taatggagat ggaactcaca ctatcacagt
     3301 tcaaaaccca gatggttctg aatcaacaac agttgttaaa gatggtaaag acggtaaaac
     3361 tgcgaatatc actacaacag aaaacccaga tggaagccac acaattacgg tgacaaatcc
     3421 agatggttca actaaagaaa ctgttgttaa aaacggtaaa gacggtaaga ctcctaaagt
     3481 tgaagtaacg gataacaacg atggaactca tactgttaaa gttacagatg gagacggcaa
     3541 tgttaccaac gctatcatca aagatggtaa agacggtaaa gctgcaacag caacaactac
     3601 tgaaaatcca gatggaagcc acacagtaac aatcactaac ccagacggaa ctaagaatga
     3661 gtttgttgtt aagaatggac gtgacggtgt tgacggacgt actccaaccg catctgttcg
     3721 tgataatgga gacggaagtc atacaatcgt tattacaaat ccagaaggtg tgacaactga
     3781 aaccacagtt cgtgatggta aatcaccaaa agtgactata actgatgaac aaaatggaac
     3841 tcataagatc tctgttctaa atggtgacgg aacaactaca acaactacag ttcgtgatgg
     3901 tagagaacca aaacttgaag ttattgataa caacgatggt tcacacacta ttaaagtgac
     3961 aggtgctgat ggtaaaggaa cgacaactac aatctttgat ggtaaatcac caaaagcgaa
     4021 catcgttgat aacggagatg gaactcatac attaacaatc gtagattctg atggtcgtga
     4081 atacaaatct attatcaaag atggtaaaga cggcaaagat agcgtttcac caactgtaac
     4141 tgttaaaaat aataacgatg gaactcacgt tgttacaatc actaatccag atggaagtaa
     4201 gacagaaatg gtgattaaag acggtaaaga tggtaaatca ccaaaagttt ctgttgaaga
     4261 taatggtgat ggtagtcata caatcacaat catcaattct gatggaactg tgacaaaaac
     4321 agttattaaa gatggtagag atggacgtga tggtcgagac ggcaaagacg gtaaagacgg
     4381 taaagatgga aaatgtggat gccaagacaa accagtaaca ccatcaaatg acaaaccagt
     4441 tcctccaaca ccaaatgtgc cgacaccaga agtaccggtt aaacctgtgc cagcgcaacc
     4501 aacaccaaat gtaccgacac cagaagtgcc agtacaacca actccagctg ttccaacacc
     4561 agaagtaccg gttaaaccag taccagcggt tccagaacaa ccagtagtac caacaccggc
     4621 tcaaccagca actccagtaa atgctaaccc agtagcacca actacaggta aagaaaaccg
     4681 tggggacaaa ttacctgaaa ctggaagcca atctgattat atctctgttc ttttaggtag
     4741 cggtattcta ttgagcctat atgtaggacg aagaaaagaa gcttaatcag ccaaaagcag
     4801 tcactaattt ctcgaaagaa gatgataagt gatagatctc gaatgaaaga atattcttag
     4861 aatgattttc ctatgatgga aaagactgct aaaaaccttg agtggtaacg ctcaaggttt
     4921 ttttggatgg ctgatgtttg tctgaaaatc ttgattgaga aataaaaagc caccctatta
     4981 ggtggctata attgatttag actttctaaa attttctatt ttttactgaa tcgcttcgac
     5041 caagtcttga gcttgttttt caagtgagtt taggactgtt tcttcaagaa ccaattttcc
     5101 gtctgcccag gcagagtcat taacacgtgc agcagtgaaa tcaccaacgc cttgtgtacg
     5161 gataaatggc aagaggtctt tgtagatagc gaaaagttga tcgtgccctg cattggctac
     5221 agatgatacg gtgacaaact tgtcttgaag ggcagaaacg ccacgcgtat cagacaagtc
     5281 aagggcacga gatagccagt caagcaagtt ttttactgta ccagggatag agaagttgta
     5341 gactggagag aaaatccaga tagcatccgc aacgagaact gcttcacgag cagcagctac
     5401 agctggatgt gttggaactt ccaaatcttg gctgaagaga ggaagggctg aataatcaag
     5461 gtagctaact tccgctttac cagcaagtgc tttctcagct tcgagcgcca tttggtggtt
     5521 gaaagaacct tgacgtagtg atccgacgat aaataatact tttttagaca tgatgtgtct
     5581 cctttttctt caaattttga gaactctctc gttgttataa aatacattac aacaaaacaa
     5641 aagaacttgc aagaaatttg ctcagagttt atttgaaaat tgtaaaattt cggaaactct
     5701 agtcatttgt gactgaaaaa gtaagaactg tttcactttc aaaatcggtt ttgtttgaag
     5761 ggagaaatag aattggttgc tcaaagcaca gctttgaggt tgcagataaa gctgacgtgg
     5821 tttgaagaga ttttcgaaga gtattcttat attcacttgt aataaagctt aatagatggt
     5881 aaaatagacg agtgaaaaaa agacaaaaca aagcaaaaaa taatctactg tggcagtatg
     5941 gtctagggat gacgattttg tttgtggtta tcagtgcttc ctttctgtat atggtttctc
     6001 ttagcatgaa accctatcaa acagctaaaa gtgaaggaga aaaattagct cagcagtatg
     6061 caggattaga gcaggccgat caggttgatt tatacaatgg cttggaatct tattacagcg
     6121 ttcttggtcg taataaacag caagaagcac ttgctgttct gattggaaaa gatgatcata
     6181 agatttacgt ttatcagcta aatcagggtg tttcacaaga aaaagcagaa acggtttcta
     6241 aggaaaaggg agctggcgaa attgacaaga ttatctttgg tcgttatcaa gataagccaa
     6301 tctgggaagt caagtcagga tctgattttt atctagtaga ttttgaaaca ggagcattgg
     6361 tcaacaagga gggcctatga aattatccaa ccgtgtttta gaaatggaag aaagtgtgac
     6421 tttggctgct ggagcccgtg ccaaagcact gaaggctgag ggtagagata ttttgtctct
     6481 aaccttgggt gagccagatt tcactactcc caaaaatatc caagatgccg ccattgcatc
     6541 gattcgagat gggcgtgctt ctttttatac agtaacctca ggtctgccag agcttaaggc
     6601 ggcggtcaat agctactttg agcgctttta cggctattct gtagcgtcaa atcaagtgac
     6661 agtcgctgcg ggagccaaat attctctcta taccttcttt atggctgtgg tcaatccagg
     6721 tgatgaagtc atcatcccaa ccccatactg ggttagctat ggagatcagg tcaagatggc
     6781 agaaggcgtt cccgtctttg tttctgctaa ggaagacaat cactttaagg tgaccgtaga
     6841 gcagttagaa gcagctcgca ctgacaagac caaggttttg gtgctgaatt cgccatctaa
     6901 tcccacaggt atgatttaca cccgtgagga actcttggca attggaaact gggctgtaga
     6961 aaatgatatt ctcatcctag cagatgatat ctatggccgc ttggtttata atggtcatga
     7021 gttcacaccg atttctagcc tatcggaagc gattcgcaag caaacagtgg tcatcaatgg
     7081 tgtgtctaaa acctatgcca tgactggttg gcggattggt tatgccgttg gagaagcaga
     7141 cattatcgct gccatgtcca agattgcagg tcaaacaact tcgaatccgt cagcagtagc
     7201 ccaatatgca gcagttgagg ctctatcagg tgagcaagat actgtagaaa gcatgcgtca
     7261 ggcctttgaa gaacgtctta ataccatcta tcccctcctt gcagaagtgc caggatttga
     7321 agtggtcaaa ccgcaagggg ccttctatct cttcccaaat gtcaaaaagg ccatggagat
     7381 gaaaggctac acggatgtga cagactttac aactgttatc ttagaagaag ccgaagtggc
     7441 cttggtaaca ggagctggat ttggagcacc agaaaatgtc cgcctcagct atgcgacaga
     7501 cctagacacg cttaaagaag cagtcgaacg cttgaaagca tttatgggta gtgagaatga
     7561 ttgatcattt tgagattaag gtaaaggatt tacaaatttc agaaggattt tataggagtt
     7621 ttctcgctcc tttggactat aaattggctt ttaagactag ttctctaatt agttttctat
     7681 ccccgaacag ccctcatcct ggtggtgatt tttggctgac tcagggaaca caagatcctg
     7741 ttcattttgc ttttttagca gaaaataagg aagaagttca ggcttgttat gaggctggct
     7801 tagaggcagg tgggcgagac aatggggctc ctggttatcg aagtgagcat ccgatttact
     7861 atgctgcttt tatgattgac ctggatggga acaatataga ggtggtttgc cataaagaat
     7921 aaaaaagaaa aggaaaaata atgacaaaac gtgtaacgat tattgacgta aaagactatg
     7981 ttggtcagga agtgacgatt ggcgcttggg ttgccaacaa atcaggaaaa gggaaaatcg
     8041 ctttcttaca attgcgtgat ggaacagcct tctttcaagg tgtggctttt aaaccaaact
     8101 ttgtcgaaaa atttggtgaa gaagtgggac ttgagaagtt tgatgttatc aaacgcttga
     8161 gccaagaaac gtctgtttat gtgacaggta ttgtcaaaga ggacgaacgt tctaaatttg
     8221 gctatgagtt ggacatcaca gacatcgaag tgatcggtga atctcaagac tacccaatca
     8281 caccaaaaga acacggaaca gactttttga tggataaccg tcacttgtgg ctacgctctc
     8341 gtaagcaagt agctgtgttg caaatccgta acgctattat ctatgcaact tatgagttct
     8401 ttgacaagaa cggttttatg aagtttgaca gcccaattct ttcaggaaat gcggcagaag
     8461 attctacaga actctttgaa actgactact tcggaacgcc agcctacttg agccaatcag
     8521 gtcaacttta cctagaagca ggggctatgg ctcttggtcg tgtctttgac tttggtccag
     8581 ttttccgtgc tgaaaaatca aaaacacgcc gtcacttgac tgagttctgg atgatggatg
     8641 ctgagtactc atacttgaca catgatgagt cgcttgactt gcaagaagct tatgtgaaag
     8701 ctcttctaca aggtgttctt gaccgcgcgc ctcaagcctt ggaaaccttg gaacgtgata
     8761 cagaactctt gaaacgctac attgcagagc cattcaaacg tatcacttac gatcaagcca
     8821 ttgacctctt gcaagagcat gaaaatgatg aagatgctga ctacgagcat cttgagcatg
     8881 gtgatgactt tgggtcacca cacgaaactt ggatttcaaa ccactttggt gtgccaacat
     8941 ttgtcatgaa ctatccagca gccatcaagg ccttctacat gaaaccagtt cctggaaatc
     9001 cagagcgcgt gctttgtgca gacttgcttg ctccagaagg ctatggagaa attatcggtg
     9061 ggtctatgcg tgaggaagat tacgatgccc ttgtcgctaa gatggatgaa cttggcatgg
     9121 atcgtacaga atatgaattc taccttgacc ttcgtaaata cggtacagtt ccacacggag
     9181 gatttggtat cggtatcgaa cgtatggtaa ccttcgcagc aggaacaaaa catatccgtg
     9241 aagctattcc attcccacgt atgttgcacc gtatcaaacc ataagaacag gaaaacgccc
     9301 atgtggcgtt ttttcgaatt ctagtgtttt tacttgcgta aaaaaaattt ttctagtata
     9361 atagtttatt gtgagcgaac ctcacttacc ccttgcaaag tcttggggtc attagaccaa
     9421 aaggaggaac atatcaatgg ctaaatacga aattctttat atcattcgtc caaacattga
     9481 agaagaagct aaaaacgctt tggtagcacg ttttgactct attttgactg acaacggtgc
     9541 aactgttgtt gaatcaaaaa cttgggaaaa acgtcgtctt gcatacgaaa tccaagattt
     9601 ccgtgaagga ctttaccaca tcgttaacgt tgaagcaaat gacgatgcag ctcttaaaga
     9661 gtttgaccgt ctttcaaaaa tcaacgctga cattcttcgt cacatgatcg tcaaaattga
     9721 cgcgtaagaa ggtaaactat gattaacaat gttgtacttg tagggcgtat gacacgtgac
     9781 gctgaattgc gttatacccc atcaaatgta gcagttgcga cttttactct tgcagtaaac
     9841 cgtacattta agagtcaaaa tggtgaacgt gaggctgatt ttatcaatgt cgttatgtgg
     9901 cgccaacagg ctgaaaatct tgctaactgg gctaaaaaag gctcacttat cggggtgaca
     9961 ggtcgtatcc agactcgtag ttacgataac cagcaaggac aacgtgtcta cgtgacagag
    10021 gtcgtggctg agaatttcca aatgttggaa agccgtagtg tgcgtgaggg tcacacaggt
    10081 ggagcttact ctgcaccaac tgcaaactat tcagcaccta caaattcagt accagacttt
    10141 tcacgtaatg aaaatccatt tggagcaaca aacccattgg atatttcaga tgatgattta
    10201 ccattctaat ggacaactaa acttataaag gagaaaaaac atggctcaac aacgtcgtgg
    10261 cggattcaaa cgccgtaaaa aagttgatta catcgcagca aacaaaattg aatatgttga
    10321 ttacaaagat actgagcttc ttagccgttt cgtttcagaa cgtgggaaaa tccttcctcg
    10381 tcgtgtaaca ggaacttcag ctaaaaacca acgtaaagta acaacagcta tcaaacgcgc
    10441 tcgcgtaatg gctttgatgc ctttcgtaaa cgaagattaa agaaaagacc cggttgggtc
    10501 tctttttcat gaacttgaaa acaagaaagc gaattaagac cccaacgggt cttttttcac
    10561 aagctttgaa atgagagagc gagttaggct cagtggctcc ctttttacga gtttgaaaac
    10621 aagagaacac attaaaagca cgatggagct ttttcataaa tatgtctttt ttttcatcca
    10681 agaaattaaa ataaaaatga taaacttttt gaaaataggg gatttgccta ctttatgata
    10741 taatggaaag agttagattg aaagaggtag tgagatggac gcgaaattaa gatacaaggc
    10801 aaagaagatc aagattgtct tttttgatat tgatgataca ttgcggaatt caaagacagg
    10861 gtttattcca actacaattc ccactgtttt taaacagttg cgtgaaaaag gaattttaac
    10921 aggaatcgcc tctggacgtg gcatttttgg tgttgttcca gagattcgtg atctcaaacc
    10981 tgactttttt gtaactttga atggggctta tatcgaagat aaaaaaggtc aggtcattta
    11041 tcagcatcag attgaaaagt catatgttga ggagtatatc tcttgggcta agcaagaagg
    11101 aattgagtat ggcttggttg ggagtcatga tgccaagttg tcgactcgca ccgatatgat
    11161 gagtgaagct atcaatccaa tttatcccga cttagatgta gatcccgatt tccatgaaaa
    11221 agaagatatc tatcagatgt ggacttttga agataaggga gatgacttgc acttgcctga
    11281 cagtctctca gacaaacttc gcatggttcg ttggcatcaa cattcgtctg atattgtgcc
    11341 gatttcaggc tccaaagcga cgggggtgga aaaggttgtg gaacaccttg gcttgaaacc
    11401 agagaaggtc atggtttttg gagatggtct caatgacttg gaactctttg attatgctgg
    11461 aatcagcgtt gccatgggaa tttctcatga taaaatcaaa gaaaaagcag attatattac
    11521 aaaaacatta gaagaagatg gcatttttga tgccttagaa gtatttggta tggtagaaaa
    11581 agaattgcat tttccacaag tagacattga aacagtagaa ggtcctcttg cgactattaa
    11641 gaccaatcac ggagacttac gtatcaagct tttccctgaa catgctccta aaacagtggc
    11701 taactttgta tctctttcaa aagatggcta ctatgatggt gtcattttcc accgtattat
    11761 caaggacttt atgatccaag gtggagaccc aactggaact ggtatgggtg gcgagtcaat
    11821 ctacggcgaa tcttttgagg atgaattctc agaagagctt tacaatatcc gtggtgctct
    11881 ttccatggca aatgctggtc caaataccaa cggcagccag ttctttatcg tgcaaaacca
    11941 acacctacct tattctaaga aagaaattac tcgtggtggt tggccagaac cgattgcaga
    12001 aatctatgcc aatcaaggtg ggacacctca cctagaccgc cgtcacacgg tttttggtca
    12061 gttagctgat gaagcatctt acgctgtctt ggatgtcatt gctgctgttg agacaggagc
    12121 tatggacaag ccagttgaag atgttgtaat tgaaactatt gaaatcgagg actaagatga
    12181 aaatcggtga taagctaaag gggcgtatta cagggattca gccctacggt gcctttgttg
    12241 agttagagac gggtgatacg gggctgattc acatttcaga aattcggaca ggatttattg
    12301 aaaatattca tgaaaccttg aaagtcgatg aagaggttca agttcaggta gtggatttag
    12361 atgaatttac ggggaaagcc agtctttcta tccgcacttt ggaggaagaa aagtaccagt
    12421 ttcctagacg gagacgcttt tcaagcgacc gctttaacta cggttttgct ccctttcgac
    12481 gaatgctacc aatctggact ggagaagccc tgcaccattt aaaaaagaag aagtagttta
    12541 gagttttata ttttttgtaa tgttaatata aatttgctat aataggacca tggaagaaga
    12601 acaattatta aaatcaggag agcgcattaa ccagctcttt tcgacagata tcaaaatcat
    12661 tcaaaataga gaggttttta gctattcggt ggatagtgtt ctcttatcac gatttccacg
    12721 ttttcctaag aaggggttga ttgtggattt ctgtgctggg aatggagcag tggggctttt
    12781 tgctagcact cgtactcaag cacagatatt gtctgttgag attcaggagc gtttggcgga
    12841 tatggctgaa cgctctgtcc gtttgaatgg attagaggag caaatgcagg tcatctgcga
    12901 tgatttgaaa aatatgcctg ctcacattca ggggagtaag gtggatatga ttttgtgtaa
    12961 tccaccctat ttcaaggtgg atccttattc taatctgaac gagagtgaac attatctctt
    13021 ggctcgacac gaaatcacga ctaatttgga agaaatctgt catagtgccc agagtattct
    13081 caagtctaat gggcgtttgg ccatggttca tcgtcctgat cgacttctgg atattttgga
    13141 tacgttaaaa cgacataatc tagcccctaa gcgcctgcag tttgtttatc caaaaagaga
    13201 aaaggaagcc aatatgcttt tgattgaggc gatcaaggat ggctcaacaa gtggctttaa
    13261 ggtcttacct cctttgattg tccacaatga tgatggctct tatacgcccg aaatcgaaga
    13321 gatttattat ggatcataag gcttatatgt acgttctgga gtgtcgtgat ggatcctact
    13381 atataggcta tacgactgat atgagaagac gcctcgctat ccacaatagt gggaagggag
    13441 ccaaatatac acgagcacgc ttgccagtca aacttatcta tgctcaaggt tttgccagta
    13501 aggaagaagc catgtcggct gaagctcttt tcaagcgtaa gaagaggcca cagaaggaag
    13561 aatttttatc tgaaaatcaa gatagaaatt tactcagtta ttttgaagaa tcgtggggag
    13621 tcctttgact cctcttacct ttgtcaaaaa gcgaaaaaaa tgctacaata aagaaaataa
    13681 acaaaatgag gtattatcat gtccaagatt ctagtatttg gtcaccaaaa tccagactca
    13741 gatgccatcg ggtcatctgt agcttttgcc taccttgcaa aagaagctta cggtttggat
    13801 acggaagctg ttgcccttgg aactccaaat gaagaaacag cctttgtctt gaactatttt
    13861 ggtgtggaag caccacgtgt tatcacttct gccaaagcag agggggcaga gcaagttatc
    13921 ttgactgacc acaatgaatt ccaacaatct gtatcagata tcgctgaagt agaagtttac
    13981 ggtgttgtag accaccaccg tgtggctaac tttgaaactg caagcccact ttacatgcgt
    14041 ttggagccag ttggatcagc gtcttcaatc gtttaccgta tgttcaaaga acatggtgta
    14101 gctgtgccta aagagattgc aggtttgatg ctttcaggtt tgatttcaga tacccttctt
    14161 ttgaaatcac caacaacaca cccaacagat aaaatcattg ctcctgaatt ggctgaattg
    14221 gctggtgtaa acttggaaga atatggtttg gcaatgttga aagctggtac caacttggct
    14281 agcaaatctg ctgaagaatt gattgacatc gatgctaaga cttttgaact caacggaaat
    14341 aatgtccgtg ttgcccaagt gaacacagtt gacatcgctg aagttttgga acgccaagca
    14401 gaaattgaag ctgcaatgca agctgccaac gaatcaaacg gctactctga ctttgtcttg
    14461 atgattacag atatcgtcaa ctcaaactca gaaatattgg ctcttggtgc caatatggac
    14521 aaggtcgaag cggctttcaa tttcaaactt gaaaacaatc atgccttcct tgctggtgcc
    14581 gtttcacgta agaaacaagt ggtacctcaa ttaactgaaa gctttaatgc gtaagatttt
    14641 gggtgtcagc tcaaaatcgg aaagtctagt ttgccttata tcgaaaggag tttcggctcc
    14701 tttttttcta ggagtgaagt atgttagaaa atggcgattt gatttttgtg agagatgggt
    14761 cagacatggg acaggccatc cagacttcca caggtaacta tagccatgtt gccatttatt
    14821 tggatgggat gatttatcat gctagtggac aggctggtgc tgtctgtcaa gaaccggcag
    14881 acttctttga gtccaatcat ttgtacgacc tctatgttta cccagaaatg gatatccagt
    14941 cggtgaagga aagagcttgc agacatcttg gagcacccta caatgcttct ttctatccag
    15001 atgcagctgg tttctactgc tcccagtata tagcagaaat cctacctatt tttgaaacta
    15061 ttcctatgaa atttggagat ggggaacagg agattagtga tttttggagg gagtattaca
    15121 tagaactagg tctgcctgtt cctctgaacc aagctgggac caatcctagt cagttggcag
    15181 catcgcctct gttacaatgt aaagaaagga atcttcatga ttcagatttt taattcatct
    15241 cgtttgacga gacagccatt tttggagaat tgatccgcta tctggaccag tatgaggatg
    15301 tgattctacg ggaaattaag gctcaatttc cagatgttgc agttgataaa ctcatggaag
    15361 agtatataaa ggcaagcttg attctacgtg aaaataagcg ctattacctc aattttccta
    15421 cgcttgaatc acttgatagt cttgaactgg atcaagagat ttttgtcaga gaagctagtc
    15481 cggtctatca agccttgttg gagcagagtt ttgagacgga attgcgcaat caaatcaatg
    15541 cagctatttt agttgaaaga cggactttgc gcgcattaaa atgaccctgt ccaattattt
    15601 ttacaaggtc aaacagcagt atcctttgac agaaaaacag caggagctct atgacatttt
    15661 aggagatgtt aatcctgagt atgcactcaa gtatatgacg gcttttttgt tgaaatttct
    15721 caaaaaagac cagcttatgc agaaatgccg tgatatcttt gtggacagtt tggttgtctt
    15781 aggctatatt gtgcaaaatg aagatagaaa gtatgagttg gctatcgatt ttgataagga
    15841 gagattaact ttctacttag cgtgatttct tgtttctgag cacattgttt gactttcctt
    15901 agtattcggt ataaactata tgtaaccggt aacacatatc ggaataaact aaaggagaca
    15961 atcatatgtc acttgaaaac aaattggaac aagcaacagg cgctgtcaaa gaaggttttg
    16021 gtaaagttac tggagacagc aagacagaac ttgaaggagc tgttgaaaaa acagttgcta
    16081 aggcaaaaga cgttgtagaa gacgcaaaag gtgctgtaga aggtgccgtt gaaggtttga
    16141 aaaacgtttt tactaaataa taggaaaaaa tcaagggttt cattttccct tgattttttc
    16201 tattcttata aataattttc tgcgacggct gtatctcctg ggtaggattc tttcttgccc
    16261 tggatgattt ggtaacaatc ggctccctta cccgcaataa taactgcatc taattcgtga
    16321 tttgtgatag ccattgccgc cttgatggct tcttggcgat ccgcaatctt ttcaacagga
    16381 tgattgatgt agctactaat ttcatctgca atggccattg ggtcttcata gttagggtca
    16441 tcagcagtca gaaagacttg aatctcaggg tgttgattga ggaggaggcc aaagtcctta
    16501 cgacgacttt ctcccttgtt tcctgttgat cccagaacca gagcaatctt tccggtttga
    16561 tgagtttcaa ccacattgat gagttttttc agactatccc cattgtgggc atagtcgatg
    16621 aagaccttgg ctccattttt ctgagtgagg acttccatac gaccaggaac gcgggttgca
    16681 gcgatgcctt ttttgatgtc ctcaagactt gctccgagac ggagacaagc aagtccagca
    16741 gcaactgcat tttcttggtt gaagttgcca atgagttgga tatcataatc tccagcgagt
    16801 ttacccgtag ctgaaaagct aaaggctttg gaattctcga tttggttatc aaattggcta
    16861 ccatagaaat catggtcttg atcttcaacc tgttctttca agactgagaa gtggtccatg
    16921 tcactgttaa tgatgactgc tcggctattt tccatcaaga gacgcttgtg gtagaaatag
    16981 tcttcaaagc tagggtgttc aatcgggccg atatggtcag gagtgatgtt aagaaagact
    17041 cctacatcaa aggtcagtcc atagactcga tggactagat aggcttgact ggagacttcc
    17101 atgatgaggt gggtacggtc attttgcaca gcctgattca tcatgtcaaa gaggtcaata
    17161 ctctcagggg ttgtcaacgc tgacttaaag aaagtctcgc catcaagagt tgtgttcatg
    17221 gtcgacaaca tagcaggtct atgcccttga gataagatgt tataggcgaa ataggttgct
    17281 gttgtcttac ccttagtacc agtaaaggca aggagtttga gtttctcttg tggattacca
    17341 tagaactcca tggcaatcaa actcatggct ttctttatat cgttcacaat gatgacaggg
    17401 atatcgactt cgtagtcctt ttcagctaca taccaagcta aaccttgtgt tatagcagaa
    17461 agaaggtatt cttttttaaa ggcagcgcct tttgcaaaaa aaagagtgtc ttctgttact
    17521 tttcggctgt cgtagctgat gctatcaaaa ataactttgc tgtagttgta gtggtaatga
    17581 ccttggtcaa taatttcgcg aaaaaggcca tctttcttta aaatatctaa tacggtttca
    17641 atcttaatca tactttctat tgtaaaccga aagtcgtaaa tttacaagta acaaggaaaa
    17701 gtttataatg gaagataagg agtttttcct agttatcaaa attgaatgag gaatctatgt
    17761 cgcacgaaaa caatcaccag caggcccaga tgttacgggg gactgcttgg ctaacggcta
    17821 gtaactttat cagtcgccta ctcggggctg tttacattat cccttggtac atctggatgg
    17881 gggcttatgc agctaaggca aatggtctct ttaccatggg ttacaatatc tatgcttggt
    17941 tcttgttggt ttcaacagcg gggattccag ttgcggtggc caagcaagtt gccaagtata
    18001 ataccatgcg agaagaagag catagctttg ccctgattcg gagcttctta ggctttatga
    18061 caggactagg cctggttttt gctttagtct tgtatgtctt tgctccttgg ctagcagact
    18121 tgtctggcgt gggcaaagac ttgatcccaa tcatgcaaag cttggcttgg ggagtcttga
    18181 ttttcccgtc tatgagtgtt atccgaggat ttttccaagg gatgaataac ctcaaaccct
    18241 atgccatgag ccaaattgct gagcaggtca ttcgtgttat ctggatgctc ctagcaacct
    18301 ttatcattat gaagctcggt tcaggagatt atctagcagc cgttacccaa tcaacctttg
    18361 ctgcctttgt cggtatggta gccagttttg cagtcttgat ttatttcctt gcccaagaag
    18421 gttcactcaa aagagtcttt gaaacaggag ataagattaa cagtaagcgt ctcttggttg
    18481 ataccattaa ggaagccatt ccttttatcc tgacagggtc tgccatccag ctcttccaga
    18541 ttttggatca gctgaccttt atcaatagta tgagctggtt taccaactac agcaatgagg
    18601 acttggttgt catgttttct tatttctcag ccaatcctaa taaaatcacg atgattttga
    18661 tttctgtagg ggtttcgatt gggagtgttg gtttgccact tttgacggaa aactatgtca
    18721 agggggactt gaaagcagct tctcgtctcg ttcaggacag tctcacccta ctctttatgt
    18781 tcttgctacc agcaacggtt ggagtggtta tggtaggaga acctctttat acggtcttct
    18841 atggtaagcc agatagtttg gctctgggct tatttgtctt tgcagttttg cagtctatta
    18901 ttttaggctt gtacatggtc ttgtctccaa tgcttcaggc catgttccgc aaccgcaagg
    18961 ccgttctcta ttttatctat ggttctattg ccaagctagt cttgcaacta cctaccatcg
    19021 ccctcttcca cagttatggt cctttgattt caacaaccat tgctctcatc attcctaacg
    19081 tcttgatgta tcgggatatt tgtaaagtaa ctggtgtcaa gcgcaaggtg attttgaagc
    19141 gaaccatttt aatcagtttg ctgaccctag tcatgtttct gttaatagga accatccagt
    19201 ggctgttagg atttttcttc caaccaagtg gacgtttgtg gagcttcttt tatgtagctc
    19261 ttgtcggtgc catggggggt ggactttata tggttatgag tctgcgtacc tatttattag
    19321 ataaggtaat aggaaaagcc caagcagatc gcctgcgagc aaaatttaag ctttcgtaag
    19381 gtagcattta taaataaaag gaataagttg aacaatcttt taggagaact tgaagcttat
    19441 tcctttttta gcgtaaaaat agctaaaatt atatttcaaa aatagaaaat gaggcttttt
    19501 tcgatttttt ggaaaaaatc attgactaaa caaactaaac gttgtataat aaaacaaata
    19561 tttaaagcag gaggttccgg aaatgaaaaa gtctaagagc aaatatctaa ccttggcagg
    19621 tcttgtcctg ggtacaggag ttttattgag cgcgtgtgga aattctagca cggcgtcaaa
    19681 aacatacaac tatgtttatt caagtgatcc atctagcttg aactatctag cagaaaaccg
    19741 cgcagcaaca tccgatattg ttgcaaattt ggtagacggg ttattagaaa atgaccaata
    19801 tgggaatatt attccatcat tagcagagga ttggactgtt tctcaggacg gtttgaccta
    19861 tacctacaaa cttcgtaagg atgccaagtg gtttacttct gagggagaag aatatgcgcc
    19921 tgtaactgcc caggattttg tgacaggttt gcaatatgca gctgataaaa aatcagaagc
    19981 cttgtatcta gtgcaggact ctgttgctgg tttggatgac tatatcactg gtaaaacaag
    20041 cgacttttca actgtcggtg tcaaggcact tgatgaccaa acggttcaat atactttggt
    20101 taaaccagaa ctttactgga attcaaaaac acttgcaacg atactttttc ctgttaatgc
    20161 agatttcctg aaatcaaaag gggatgattt tgggaaggcg gatccatcta gtattttgta
    20221 caatggacct ttcttgatga aagcacttgt ctcaaaatct gctattgaat ataagaaaaa
    20281 ccctaattac tgggatgcta agaatgtctt tgtagacgat gtgaaattga cctactatga
    20341 tggtagcgac caagaatcac tggaacgtaa ttttacagct ggtgcttata ctacggctcg
    20401 tctttttcct aacagctcca gctatgaagg gattaaagaa aaatacaaaa acaatatcat
    20461 ctatagtatg caaaattcaa cttcatattt ctttaatttt aacctagata ggaagtctta
    20521 caattatact tctaaaacaa gtgacattga aaagaaatcg actcaggaag cagttctcaa
    20581 taaaaacttc cgtcaggcta tcaattttgc ttttgacaga acatcttatg gggctcagtc
    20641 tgaagggaaa gaaggtgcaa caaagatttt gcgtaaccta gtggttcctc caaactttgt
    20701 cagtatcaag ggaaaagact ttggtgaagt tgtagcctct aagatggtca actatggtaa
    20761 ggaatggcaa ggtatcaact ttgcggatgg tcaagaccct tactacaatc ctgagaaagc
    20821 caaggctaag tttgcggaag ctaagaaaga actcgaagca aagggtgttc aattcccaat
    20881 ccacttggat aagactgtgg aagtaacaga taaagtaggc atacaaggag ttagttctat
    20941 caaacaatca attgaatctg ttttaggttc tgataatgta gtgattgaca ttcagcaatt
    21001 aacatcagat gagtttgaca gttcaggcta ctttgctcaa acagctgctc agaaagacta
    21061 tgatttatat catggcggtt ggggacctga ttatcaagac ccgtcaacct atctcgatat
    21121 ttttaatact aatagtggag gatttctgca aaatcttgga ctagagcctg gtgaggccaa
    21181 tgacaaggct aaggcagttg gactggatgt ctatactcaa atgttggaag aagctaataa
    21241 agagcaagat ccagccaaac gttatgagaa atatgctgat attcaagctt ggttgattga
    21301 tagttcttta gttcttccaa gtgtttcgcg tgggggaaca ccatcattga gaagaaccgt
    21361 accatttgct actgcctatg gtttaaccgg tacaaaaggg gttgaatcat ataaatacct
    21421 caaagtacaa gataagattg tcacaacaga cgaatatgca aaagccagag aaaaatggtt
    21481 gaaagaaaaa gaagaatcca ataaaaaagc ccaagaagaa ttggcaaaac atgtcaaata
    21541 aaatctaatt gtagataagt ttgtgtaaga agtctttgtg cttaaaaacg cataatatca
    21601 ggtatataaa atcctagatg ttatgcgttt tgttatagga agatttatta gattttatcc
    21661 tcaaattgag ttattcccga ctttatccgt tgaaatatta taaggagtat ttatgaaatt
    21721 aaaattatta agagtagata ctaaggtgat tatggggagt ttcttacttg ttctgtctag
    21781 tctacttgct ttgttgcttc cccttatctt aaagggttta atagatggga gttctattga
    21841 aaatataggt tccaaagtat ttcaatcgtt tttgattttt attggtcaag ccttgttttc
    21901 ttctattggt tactatctgt ttagtcaatc gggtgaaaaa aagatagcaa aaatcaggaa
    21961 aaaagtgata gaggggttga tttatgcaga gaaatccttc tttgataaga gccaaagtgg
    22021 ggagttgact tctgccattg tcaatgacac gagtgtcatt cgtgagtttt taattacgac
    22081 tttcccaaat attattctga gtttagttat ggtacttggt tccattgtag tcttatttag
    22141 tcttgattgg aatctttctc tacttttatt catcactctt ccttgtatga tgtttattat
    22201 cttgctcctt tccaatatca gtgaaaagta tagtcgtcgt ttacaggagg aaatcggatt
    22261 tttaacaggg caattgactg aaaagattca agaacatgaa ttaattaaga ctaaccaagc
    22321 agagaaaagt gtacaggatg ttttggataa ttgtattgaa agggtacaaa acaattcact
    22381 gaaatcagat agggttactt cttttgagac cccgtttgct ctcttattta tctttgcgac
    22441 tatagctgtg atgctaacct atgggggtta tcgggtcagc gcaggatata tatctgtggg
    22501 aaccttggtt tcgtttttga tttacctctt tcaattactt aatcctatta gtaatatagc
    22561 taattttgta actgtttatt ctaggagcaa gggatcttca gttgcactgg agaacttgct
    22621 tgcagttcct aaagaaaaat ttgagtgagg aaaatcggta tcaggacaag ggttgaattt
    22681 taaccatgtc tattttggtt atgatgaaaa tcgacctgtc ttaaaggata ttacttgttc
    22741 aattttcaag gggcaaaaaa ttgcttttgt tggaccatct ggatcaggaa aatcaacgat
    22801 tgtgcgtttg ttagagcggt tttataaacc gctttcagga gatattctaa tggagcaatc
    22861 aagtatatat gattttaact taaaagaatg gagaagtaaa atcgcttagt aactgatgat
    22921 gaattgatga aagtgctaga cttagtatca ctaggtgatg agattcgctc catgaaagag
    22981 ggactagata ctgaagttgg tgaacgcgga cgactcttgt caggggggca aagccaaaga
    23041 cttcaaatag ctagagccta cttaaaagat gctgaaattc ttatatttga tgaagccact
    23101 gctaatcttg atgcggattc tgagtatgcg attatcagta gcctctattc tgtattaaag
    23161 gagaagacgg ttgtgattat agcgcatcgt ttgtcaacgg taaaagatgt ggattgtatt
    23221 ttcttcttag aggaggggaa aatcactggc tcaggaactc ataaggaact actggaaaat
    23281 catgagcgtt atgctcgttt tgtgcaggag caaatgatag agtgaaggtg tcttttgaga
    23341 ttcaccattt tatagtctat taaagggagc aggaaaaact ccctttttat atagtttgaa
    23401 actataacta gctcttgaaa agaagaaaat gagttgatga aaataagtgg tacaatagtt
    23461 actatagatt tggaggtatt gtatgagcaa ggaattacac attaacacaa ttttggccca
    23521 ggcgggtatt aagtcagatg aagcgacagg tgcattggtg acaccgcttc atttttcaac
    23581 gacctatcag catccagagt ttggtcgatc tactgggttt gactatacgc gcactaaaaa
    23641 tccaactcgt agtaaggctg aggaagtctt ggcggctatt gagtcagcag actatgccct
    23701 agcgactagc tcagggatgt cagctattgt actggccttt agcgtctttc cagtaggaag
    23761 taaggtcttg gcagtgcgtg atctttacgg tggttctttt cgctggttta accaagtgga
    23821 gcaggaaggt cgtttccatt ttacctatgc caatacagaa gaagagttga ttgccgagtt
    23881 agaaaaggat gtggatgttc tctatatcga aaccccaacc aatcccttga tgttggaatt
    23941 tgatatcgaa aaactagcaa aattggctca tgctaagggt gccaaagtgg tggtggacaa
    24001 taccttctat agccctatct accaacgtcc gattgaagat ggagcagata tcgttctcca
    24061 ttcagcaacc aagtatctag caggccacaa tgatgtcttg gctggagtgg ttgtgaccaa
    24121 tagtttagaa ctatacgaga agctttttta caatctcaat acaacagggg cagtcttgtc
    24181 tccatttgac agctaccagt tgcttcgtgg tctcaagacc ttatctcttc gtatggagcg
    24241 ctcaacagct aacgcccaag aagtggttgc ctttttgaag gattctccag cagttaagga
    24301 agttctctac actggtcgtg gaggcatgat ttcctttaaa gtagccgatg aaacacgcat
    24361 tcctcatatt ttgaacagtc tcaaggtctt ctcttttgcg gaaagtttgg gcggagtgga
    24421 aagtcttatt acttatccaa cgactcaaac tcatgctgat attccagcag aagtacgcca
    24481 ttcttatggt ttgacagatg acctcttgcg tttgtctatt gggattgagg atgctagaga
    24541 tttgattgca gatttgcgcc aagccttaga aggataagac aaagatggga aaatatgatt
    24601 ttacaagcct gcccaaccgt ttagggcacc atacctataa atggaaagaa acagaaacgg
    24661 atagtgaagt tctaccagct tggatagcgg atatggactt tgtggtcttg cctgaaatcc
    24721 gccaagccgt gcaaacttac gcagaccaac tggtttatgg ttatacctat gccagtgaag
    24781 acttaattaa ggaaattcaa aagtgggaag ctacacaata cggttacaac tttgacaaag
    24841 aggctcttgt ctttatcgag ggtgtggtac cagccatctc aacagctatt caaaccttta
    24901 caaaagaagg cgaggcggtt ttaattaaca cgcctgtcta cccacccttt gctcgcagtg
    24961 tcaagttgaa taatcgtaga ttgattacta attccttagt ggaaaaggat ggtctgtttg
    25021 agattgactt tgaccaactt gaaaaggatt tggtggaaga ggaggttaaa ctctatattc
    25081 tttgcaaccc tcacaatcct ggtggacgtg tttgggaaaa agaagtgttg gagaagattg
    25141 gccaactttg ccaaaaacac ggtgttttgt tagtttcgga tgagattcac caagatttga
    25201 ccctctttgg tcacaaacac cagtctttca ataccatcaa tcctgccttc aaaaattttg
    25261 ctatcgtctt gagcagtgcc actaaaacat ttaatattgc tggaacaaaa aattcctatg
    25321 cagtcattga aaatcctaag ttgagactgg ctttccagaa acgcctgttg gccaataatc
    25381 agcatgaaat ttcaggcttg ggttatttgg cgacagaagc tgcctatcga tacggtaaag
    25441 attggctaga ggaactcaag caagtctttg aagaccacat caattatgtg gtggatctat
    25501 ttggaaaaga gactaaaatc aaggtcatga aaccgcaagg tacctacttg atttggcttg
    25561 acttttcagc ctatgacctg actgatgaaa cattgcaaga gttgttgaga aatgaagcca
    25621 aggttatcct caaccgtggt ttggattttg gagaggaagg aagtctccat gcccgcatca
    25681 atatagctat gcccaaatct ctgttgcaag aagtctgtca gcggattgtg gctacttttg
    25741 ccaaacgtta aaaatccagc cttctaggag aaaagtcttc ctagaaggct attttcatag
    25801 gcgaaaatat ggtataataa aaagataagg taaaggtgaa aatatggcta aattgattcc
    25861 ggggaaaatt cgtatcgaag gtgttgccct ttatgaaact ggtaaggttg atatcatcaa
    25921 ggaaaagaac aatcggctct acgctcgcgt tgcagaagaa gaactgcgct atagtttaga
    25981 ggatgatttg gttttttgtg cctgtgattc ttttcaaaag aggggctact gtgtgcattt
    26041 ggcagcgcta gagcattttc tgaaaaatga tgagcgtggt caggaaatct tgtggagtct
    26101 ggaagaaggt catgaagaaa aagaggccgt tgaaaccaag gtgaccttgg gtggcaagtt
    26161 tttgaatcga attttatctc caaaatcaga atgcgcctat gagttatcag ctgtgggtca
    26221 ggtggaagca ggaaccaatc atatcttgtg gactctgaga atcggccaaa tcaatagcca
    26281 aaaatactat gtcattcggg atattccact ttttttaagg attgtcgagc agagaaagtc
    26341 gtatatgatt ggcaagattt atgaggagtc tctttcttgg gaagcctttg atgatgccag
    26401 ccaagaactt ttgactttct tgcacggact aacggaggaa gggctggttc cagacctctt
    26461 tttccaaaac caaggtcggc acctcttttt ccctctgacc ttttttgagc agggtgtgaa
    26521 tttactgatg gccttgcccc attttcaatt tgaccatcaa gtggatagct accaaaccct
    26581 gctttttcag gatatgcatg ctgatgccaa tctatttgcc tttacagtaa cagaatactc
    26641 ggactatttt gaaatggaaa tcagtgagag tcctagggtc aatgtctttt atcagggagc
    26701 agtacttttc cataaaggtc aggtttattt tttaacagac cagcagatgc gtcttctcaa
    26761 ggaaattaaa gcgttacctg tgggtcaaca aggaaagaaa tacctgcaat ttgatagcag
    26821 tgatcgagac aaattggcct cctgtctgac tctttttatc cagatgggca ccgtttcagc
    26881 tccagaacgt ctacaaatca aaacttttgc gccctctttt tactttgaca gggaagaaga
    26941 taatcggatt cgtttagaaa ttcagtttga ttatggaaat agacaggtat ctagccgaca
    27001 agagctagaa gaattaccat tttcaagtga cgcggactta gaagaaagaa ttttccaagt
    27061 ctgtttggct gcgggctttg aagccgattt tcaatcttgg cgtcaggcct taaaagcgga
    27121 gtctgtctat catttttttc atgatatcat tccagtcttt gaaaaactcg ggcatgttga
    27181 cctatcagat aaactagaag agctttatag cctagcgagt cctcaggtgc agattgcctc
    27241 caagggaggt ctcttggaaa tccagtttga ttttcaaaat attgcccagg aggaaatcga
    27301 ccaagccatg caggccttgg ttgccaatca ggatttttat attgattcgt ctaatcaagt
    27361 ttactttttc gatgaagaaa ccaagaaaat tcgccaaaat ctacaggaac tggggcaatt
    27421 tgaattaaaa gatgggacct tgcaggctcg gaaatccttg gcctacagtt tagctcatct
    27481 ctttgaaggg cgagaccgtg tttctttttc acaagaattc cagaatctgg cccaggattt
    27541 gacgcatcca gaggactttc ctttgcaagc aactcaggtc aaggctgact tgcgagatta
    27601 tcaggaaaag ggaattggct ggttgcagat gctccatcat tatggttttg gtgggatttt
    27661 ggctgatgat atgggacttg ggaaaaccct tcagaccatt gcttttttga ctagtcaagt
    27721 gacaaaagaa agtcgagtct tgattctcgc tccgtcgggt ttgatttaca actgggcgga
    27781 tgagtttcag aaatttgccc cacagttgga tgtggctgtt gttcatggtt tgcaagcaag
    27841 tcgtgaggag attcttgccg agagccatca aatctatgtg actagctatg ccaccttccg
    27901 tcaggacagt gagttttatc aggggatggc ctttgacttc cttttcttag atgaggctca
    27961 ggtcatgaaa aatgcccaga ccaagattgc ccagaccttg agacaatttg tggtgccgtc
    28021 ggtctttgcc ttgtcaggaa ctccgattga aaaccatctg ggtgagttgt ggtctatttt
    28081 ccaaatcgtc atgcccggac ttttgccaag caagaaagaa tttatgaaat tgccagcaga
    28141 gcgagtggct cagtttatca agcctttcgt gatgcgacgc aagaaagaag aagttctgac
    28201 tgaattgcca gacttgattg aggtggttta taaaaatgaa ctggaagacc agcaaaaggc
    28261 tatttacctt gcccagttac aacagatgcg agaccatctg gctcaagtgt cagaacagga
    28321 atttcagcga agtcgtgtgg aaattttatc tggtttgatg cgcttgcgtc aaatatgtga
    28381 cactcctgcc ctgtttatgg aagattatca gggagccagc ggcaaactag atagtctccg
    28441 agacctactg gtacaggtgg cagacggcgg acaccgtgtc ttgattttct ctcagttcaa
    28501 gggaatgttg gaaaaaattg aacaagaact gccagacttg ggcctgactt cctttaaaat
    28561 tacgggttca accccagcca aggaaagaca agacatgacc aaggccttta atcaaggaga
    28621 aagagatgcc tttctgattt ccctcaaggc tggtggggtc ggtctgaacc tgacaggtgc
    28681 agatacagtg atcttggttg acctttggtg gaatcctgcg gtggaagcgc aagccattgg
    28741 ccgtgcccat cggatgggtc aggaagaaac ggttgaggtc tatcgcttgg tgaccaaggg
    28801 aaccattgaa gaaaaaattc aggaactcca agaacaaaag aaacatctgg tgtcacaagt
    28861 attggacggc acagagtcac gtggtagtct gaccctagca gaaattagag aaattttggg
    28921 aatttctgaa gccagcactt gaaaaatcaa gacaatacgc tataatgaag tgttgaaagg
    28981 aaatagaaaa tgaaacaaga acgatttcca ttggtgtcag atgacgaggt catgttgact
    29041 gaaatgccag tcatgaatct ctatgatgag tctgatctga tcagtaatat caagggtgag
    29101 tatcgagata aaaattattt agaatgggct cctattgctg aagaaaaacc agtaaaaccg
    29161 attgaaaagc aagtagggaa acctaaaaaa gctcctttag gggttaaaaa agaaggaaag
    29221 agctatgcgg aggtggcgcg tgaagaagcg cgtgcagact tgaaaaagaa acgctctgct
    29281 aactatctaa ctcaggattt cagccttgcg agacgtcatt ctcagcccag tctagttaga
    29341 cagggcaatc aaccgacaac tcctttccaa aaggaaaatc ctggtgaatt tgtcaaatat
    29401 agccaaaaat tgacccagtc tcattatatc ttggcggaag aagttcattc tatccctacc
    29461 aagaatgaag aagtgtcagc acctgctcca aagaaaaaca attatgattt tctaaagaag
    29521 agccaaatct acaataaaaa aagtaaacaa acagaacaag aacgtcgggt tgcccaagag
    29581 ttgaatctga ccagaatgac agaataggga gaaaacatgt caaagacata tcattttatc
    29641 ggaattaagg gatcagggat gagtgccttg gccttgatgt tgcaccagat ggggcacaag
    29701 gttcagggat cagatgttga aaagtactac tttacccaac gcggtcttga gcaggcagga
    29761 attaccattc ttccttttga tgaaaagaat ctagacggtg atatggaaat tatcgctgga
    29821 aatgcctttc gtccagataa caacgtcgaa attgcctatg cggaccaaaa tggtatcagc
    29881 tacaaacgtt accatgagtt tctaggtagc tttatgcgtg actttgttag catgggagta
    29941 gcaggagcac atggaaaaac ttcaacgaca ggtatgttgt ctcatgtctt gtctcacatt
    30001 acagatacca gcttcttgat tggagatggg acaggtcgtg gttcggccaa tgccaaatat
    30061 tttgtctttg aatctgacga atatgagcgt cacttcatgc cttaccaccc agaatactct
    30121 attatcacca acattgactt tgaccatcca gattatttca caagtctcga ggatgttttc
    30181 aatgccttta acgactatgc caaacaaatc accaagggtc tttttgtcta tggtgaagat
    30241 gctgaattgc gtaagattac gtctgatgca ccaatttatt attatggttt tgaagctgaa
    30301 ggcaatgact ttgtagctag tgatcttctt cgttcaacaa ctggttcaac cttcaccgtt
    30361 catttccgtg gacaaaactt ggggcaattc cacattccaa cctttggtcg tcacaatatc
    30421 atgaatgcga cagccgttat tggtcttctt tacacagcag gatttgattt gaacttggtg
    30481 cgtgagcact tgaaaacatt ttccggtgtt aaacgtcgtt tcactgagaa aattgtcaat
    30541 gatacagtga ttatcgatga ctttgcccat catccaacag aaattattgc gaccttggat
    30601 gcggctcgtc agaaataccc aagcaaggaa attgtagcag tctttcaacc gcataccttt
    30661 acaagaacca ttgccttgtt ggacgacttt gcccatgctt taaaccaagc agatgctgtt
    30721 tatctagcgc aaatttatgg ctcggctcgt gaagtagatc atggtgacgt taaggtagaa
    30781 gacctagcca acaaaatcaa caaaaaacac caagtgatta ctgttgaaaa tgtttctccg
    30841 ctcctagacc atgacaatgc tgtttacgtc tttatgggag caggagacat ccaaacctat
    30901 gaatactcat ttgagcgtct cttgtctaac ttgacaagca atgttcaata ggatgttccc
    30961 atggaaattc caattaagat cattcaggca agcaagtctg atttgcctga gataggggca
    31021 cttcagacct cgtcttttcc agctgaaaag cagcaacttt cccatatttt agaagaaagt
    31081 atccgtaagt gtgcggatac ctttcttcta gctagggatg aaaatcaact tttaggctat
    31141 attttatcaa gtccccagtc agacaatccg caatatctaa aagtacattc tttagtcatc
    31201 gagtctgacc atcagagaca gggcttggga acacttcttc ttgcagcctt gaaagaggtg
    31261 gcagttgatc tggattacaa agggattcgt ttggagagtc ctgatgagct gctttcctat
    31321 tttgaaatga acggttttgt tgatgaagaa gcaactttgc tctatgcaac tagccagggc
    31381 tatagtatga tttggtttaa tcccttttat ctggaggaac aatgaaaatc agacaagcaa
    31441 gattagaaga tttggatcgg attgttgaac ttgaatttga aaatttttcg gtcgaagaag
    31501 ccattcctcc ttctgtcttt gaagcacatt tgagagaaat tcagacctct tttctggttg
    31561 ctgaaaaaga aggaagaatc atgggttata tcgaaggacc agttggcctg caccgccatc
    31621 tgcaagacca gtcttttaca gaagaaataa aagactatag tcatgagcct ggtggttata
    31681 tctctgtgac ctgtctgtct attgccaagg aggcacaggg actcggactg ggtcagaaat
    31741 tgctgacagc tttgaaagaa gttgctcttg aagatgagag agatggcatt aatctaacct
    31801 gtcatgacta tctcatcgcc tattatgaaa aacatggatt tgtcaacgaa ggccagtccc
    31861 agtcaacctt tgcaggggaa acatggtatg atatggtctg ggaaatgaaa aaataagtta
    31921 ggaaaagtat catagattgc tttttttgga cttttaagat ataatattat ggattatcaa
    31981 caaggaggaa aaacttttga gtgaaaagtc aagagaagaa gagaaattaa gctttaaaga
    32041 gcagattctg agagatttag aaaaagtaaa aggctatgat gaagttctga aagaagatga
    32101 ggcagtagtt cgcactcctg caaatgaacc ttcagctgaa gaactcatga ctgattcctt
    32161 gtcaacggta gaggagatta tgagaaaagc tcctaccgtg cctactcacc caagtcaagg
    32221 tgtaccagct tctccagcag atgagattca aagagaaact cctggtgttc caagtcatcc
    32281 aagtcaagat gtaccttctt ctccagcgga agaaagtgga tcaagaccag gtcctgttag
    32341 acctaagaaa cttgaaagag aatacaatga aaccccaaca agggtagctg tttcctatac
    32401 gacggcagag aaaaaagcag aacaagcagg tccagaaaca cctacgcctg ctacagaaac
    32461 agtggatatc atcagcgata catcacgtcg tagccgtaga gaaggagcaa aacccgttaa
    32521 tcctaagaaa gagaagaagt cacatgtgaa agcttttgtg atttcattcc ttgtattcct
    32581 tgccttgctc tcagcaggtg gttactttgg ttaccagtac gtgctagatt ctttgttacc
    32641 tatcgatgct aattctaaga aatatgtgac ggttggaatt ccagaaggtt caaacgttca
    32701 agaaatcggt acgacgcttg aaaaagctgg tttggtaaag catggtctga tttttagttt
    32761 ttatgccaag tataaaaatt ataccgactt gaaagcaggt tactacaatt tgcaaaagag
    32821 tatgagtaca gaagacttac tcaaagagtt gcaaaaaggt ggaacagatg aaccgcaaga
    32881 acctgtactt gcgactttga caattccaga aggttatacc ttggatcaga ttgctcaagc
    32941 tgtgggtcaa ttgcaaggtg acttcaaaga gtctttgaca gcggaggctt tcttggctaa
    33001 agttcaagat gagacgttta tcagtcaagc agtagcgaaa tatcctactt tactggaaag
    33061 tttgcctgta aaagacagcg gtgcgcgtta tcgtttggaa ggataccttt tcccagctac
    33121 atactctatc aaggaaagca caactattga gagcttgatt gatgagatgt tagctgctat
    33181 ggataagaac ctatctcctt actatagtac tatcaaatct aaaaatttga ctgtcaatga
    33241 gttgttgacc attgcttcct tggtcgaaaa agaaggtgcc aagacagaag atcgtaagct
    33301 cattgcaggt gtattctaca atcgtttaaa tcgtgatatg ccacttcaaa gtaatattgc
    33361 aatcttgtat gcccaaggaa aactggggca aaatatcagt ctagctgagg atgttgcgat
    33421 tgataccaac attgattcac cttataatgt ttataaaaat gtaggtctca tgcctggtcc
    33481 agtcgatagt ccaagtctgg atgcgattga gtcaagcatc aatcaaacta agagcgataa
    33541 cctctacttt gtagcagatg tcacagaagg caaggtctac tatgctaaca atcaagaaga
    33601 ccacgaccgc aatgtcgctg aacatgtcaa cagcaaatta aactaaacaa actaaaatta
    33661 tgtgatacgt cacataattt tctttagaaa atattatcag aagaaagttg agaaaaatgg
    33721 cagaaaaaac atatcctatg acccttgagg aaaaggaaaa acttgaaaaa gaattagaag
    33781 aattgaaatt ggttcgtcga ccagaagtgg tagaacgcat taagattgcc cgttcatacg
    33841 gtgacctttc agaaaacagt gagtacgaag cagctaagga tgaacaagcc tttgtcgaag
    33901 gacaaatctc tagcttagaa acaaaaatcc gctatgctga aatcgtcaat agcgacgcag
    33961 ttgcccagga cgaagtagcg attggtaaaa cagtcaccat ccaagaaatt ggtgaggacg
    34021 aagaagaagt ttatattatc gtaggttcag ctggtgcgga tgcctttgca ggtaaggttt
    34081 caaatgaaag cccaattggg caggccttga ttggcaagaa aacaggtgac acagcaacca
    34141 ttgaaacgcc tgttggtagc tatgatgtaa aaatcttgaa ggttgaaaaa acagcctaaa
    34201 aacagaaaaa ggagtgggga ggcgatgtgc ttcactcact cctttttcca ttttgctatt
    34261 cttcgaaaat ctcttcaaac cacgtcagcg tcgccttgcc gtatgtatgg ttactgactt
    34321 tgtcagtttc atctacaacc tcaaaac
//
LOCUS       DAVAZT010000020        33324 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVAZT010000020 DAVAZT010000000
VERSION     DAVAZT010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33324
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.020"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..327
                     /locus_tag="VQT45_000886"
     CDS             <1..327
                     /locus_tag="VQT45_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET2359232.1"
                     /translation="KPQTEKPEEETPREEKPQSEKPESPKPTEEPEEESPEESEEPQV
                     ETEKVEEKMREAEDLLGKIQDPIIKSNAKETLTGLKNNLLFGTQDNNTIMAEAEKLLA
                     LLKESK"
     gene            749..979
                     /locus_tag="VQT45_000887"
     CDS             749..979
                     /locus_tag="VQT45_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HET2359233.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAIKC"
     gene            1383..2096
                     /locus_tag="VQT45_000888"
     CDS             1383..2096
                     /locus_tag="VQT45_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HET2359234.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            2154..2756
                     /locus_tag="VQT45_000889"
     CDS             2154..2756
                     /locus_tag="VQT45_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359235.1"
                     /translation="MSEVDFNEAVNYEFTSDTCQLANSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLNMNRNGCMGDFPHDFF
                     DIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSNFDDFLEKNYLKTIWQ
                     VSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            2892..3545
                     /locus_tag="VQT45_000890"
     CDS             2892..3545
                     /locus_tag="VQT45_000890"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HET2359236.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            3555..4019
                     /locus_tag="VQT45_000891"
     CDS             3555..4019
                     /locus_tag="VQT45_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET2359237.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            4032..5300
                     /locus_tag="VQT45_000892"
     CDS             4032..5300
                     /locus_tag="VQT45_000892"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HET2359238.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            5314..5574
                     /locus_tag="VQT45_000893"
     CDS             5314..5574
                     /locus_tag="VQT45_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359239.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            5585..6946
                     /gene="pdrM"
                     /locus_tag="VQT45_000894"
     CDS             5585..6946
                     /gene="pdrM"
                     /locus_tag="VQT45_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HET2359240.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            7100..8068
                     /locus_tag="VQT45_000895"
     CDS             7100..8068
                     /locus_tag="VQT45_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HET2359241.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            8084..9076
                     /locus_tag="VQT45_000896"
     CDS             8084..9076
                     /locus_tag="VQT45_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HET2359242.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDKNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYISEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            9294..10337
                     /locus_tag="VQT45_000897"
     CDS             9294..10337
                     /locus_tag="VQT45_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HET2359243.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            10401..12086
                     /gene="lpdA"
                     /locus_tag="VQT45_000898"
     CDS             10401..12086
                     /gene="lpdA"
                     /locus_tag="VQT45_000898"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HET2359244.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEIIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMQSPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEIIGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            12150..13139
                     /locus_tag="VQT45_000899"
     CDS             12150..13139
                     /locus_tag="VQT45_000899"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HET2359245.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(13206..14276)
                     /gene="xerS"
                     /locus_tag="VQT45_000900"
     CDS             complement(13206..14276)
                     /gene="xerS"
                     /locus_tag="VQT45_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HET2359246.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(14860..16410)
                     /locus_tag="VQT45_000901"
     CDS             complement(14860..16410)
                     /locus_tag="VQT45_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HET2359247.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFIIIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGSLVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(16426..17205)
                     /locus_tag="VQT45_000902"
     CDS             complement(16426..17205)
                     /locus_tag="VQT45_000902"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HET2359248.1"
                     /translation="MATIKEIKELLVTVKELESPIFLDLEKDNRSGVQKEISKHKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQVVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(17192..18043)
                     /gene="ylqF"
                     /locus_tag="VQT45_000903"
     CDS             complement(17192..18043)
                     /gene="ylqF"
                     /locus_tag="VQT45_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HET2359249.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EGLDGND"
     gene            complement(18250..18426)
                     /locus_tag="VQT45_000904"
     CDS             complement(18250..18426)
                     /locus_tag="VQT45_000904"
                     /inference="COORDINATES: protein motif:HMM:NF012948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2359250.1"
                     /translation="MQAGIPTDNEVSYALIYQQETLPATGSSTSALTALGLLAVGSLV
                     LLVHNMTGTVFCSL"
     gene            complement(18478..24369)
                     /gene="iga"
                     /locus_tag="VQT45_000905"
     CDS             complement(18478..24369)
                     /gene="iga"
                     /locus_tag="VQT45_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin A1 protease"
                     /protein_id="HET2359251.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGSIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVTDKG
                     ETEVQPESPDTVVSDKGEPEQVAPLPEYKGNIEQVKPETPVEKTKEQGPEKTEEVPVK
                     PTEETPVNPNEGTTEGTSIQEAENPVQPAEESTTNSEKVSPDTSSENTGEVSSNPSDS
                     TTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSNQETEKPVQPAEETQTNS
                     GKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSGNTTSENGQTEPEKKLEL
                     RNVSDIELYSQTNGTYRQHVSLDGIPENTDTYFVKVKSSAFKDVYIPVASITEEKRNG
                     QSVYKITAKAEKLQQELENKYVDNFTFYLDKKAKEENTNFTSFSNLVKAINQNPSGTY
                     HLAASLNANEVELGPDERSYIKDTFTGRLIGEKDGKNYAIYNLKKPLFENLSGATVEK
                     LSLKNVAISGKNDIGSLANEATNGTKIKQVHVDGVLAGERGVGGLLAKADQSSIAESS
                     FKGRIVNTYETTDAYNIGGLVGHLTGKNASIAKSKATVTISSNTNRSDQTVGGLAGLV
                     DQDAHIQNSYAEGDINNVKHFGKVAGVAGYLWDRTSGEEKHAGELTNVLSDVNVTNGN
                     AITGYHYTGMKVANTFSSKANRVFNVTLEKDEVVSKESFEERGTMLDASQIVSKKAEI
                     NPLTLPTVEPLSTSGKKDSDFSKIAHYQANRALVYKNIEKLLPFYNKSTIVKYGNLVK
                     ENSLLYQKELLSAVMMKDDQVITDIVSNKQTANKLLLHYNDHSSEKFDLKYQTDFANL
                     AEYNLGNTGLLYTPNQFLYDRDSIVKEVLPELQKLDYQSDAIRKTLGISPEVKLTELY
                     LEDQFSKTKQNLGDSLKKLLSADAGLASDNSVTRGYLVDKIKNNKEALLLGLTYLERW
                     YNFNYGQVNVKDLVMYHPDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYGISLAS
                     QHGTTDLFSTLEHYRKVFLPNTSNNDWFKSETKAYIVEEKSTIEEVKTKQGLAGTKYS
                     IGVYDRITSATWKYRNMVLPLLTLPERSVFVISTMSSLGFGAYDRYRSSDHKAGKALN
                     DFVEENARETAKRQRDHYDYWYRILDEQSREKLYRTILLYDAYKFGDDTTSGKATAEA
                     KFDSSNPAMKNFFGPVGNKVVHNQHGAYATGDGVYYMSYRMLDKDGAITYTHEMTHDS
                     DQDIYLGGYGRRNGLGPEFFAKGLLQAPDQPSDATITINSILKHSKSDSTEGSRLQVL
                     DPTERFQNAADLQNYVHNMFDLIYMMEYLEGQSIVNKLSVYQKMAALRKIENKYVKDP
                     ADGNEVYATNVVKELTEAEARNLNSFESLIDHNILSAREYQSGDYERNGYYTIKLFAP
                     IYSALSSEKGTPGDLMGRRIAYELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLYGK
                     ERGLVTDELVLKKVFDGKYKTWAEFKTAMYQERVDQFGNLKQVTFKDPTKPWPSYGTK
                     TINNVDELQALMDQAVLKDAEGPRWSNYDPEIDSAVHKLKRAIFKAYLDQTNDFRSSI
                     FENKK"
     gene            complement(24578..25756)
                     /locus_tag="VQT45_000906"
     CDS             complement(24578..25756)
                     /locus_tag="VQT45_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359252.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCRNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLPLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWILNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            complement(25926..29576)
                     /gene="addA"
                     /locus_tag="VQT45_000907"
     CDS             complement(25926..29576)
                     /gene="addA"
                     /locus_tag="VQT45_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HET2359253.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEICSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHQDTWKLAKTFQTFMSHFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALVEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIDEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQIIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTALGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            complement(29573..32848)
                     /gene="rexB"
                     /locus_tag="VQT45_000908"
     CDS             complement(29573..32848)
                     /gene="rexB"
                     /locus_tag="VQT45_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HET2359254.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQTTEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPISPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            complement(33048..33203)
                     /locus_tag="VQT45_000909"
                     /pseudo
     CDS             complement(33048..33203)
                     /locus_tag="VQT45_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
BASE COUNT         9515 a         6539 c         6861 g        10409 t
ORIGIN      
        1 aaacctcaga cagaaaaacc tgaggaagaa acccctcgag aagagaaacc gcaaagcgag
       61 aaaccagagt ctccaaaacc aacagaggaa ccagaagaag aatcaccaga ggaatcagaa
      121 gaacctcagg tcgagactga aaaggttgaa gaaaaaatga gagaggctga agatttactt
      181 ggaaaaatcc aggatccaat tatcaagtcc aatgccaaag agactctcac aggattaaaa
      241 aataatttac tatttggcac ccaggacaac aatactatta tggcagaagc tgaaaaacta
      301 ttggctttat taaaggagag taagtaaagg tagcagcatt ttctaactcc taaaaacagg
      361 ataggagaac gggaaaacga aaaatgagag cagaatgtga gttctagttc tcattttttt
      421 catgaaaatg tgcaaaatat agtagattga aactagaata gtatacctct acttctaaaa
      481 cattgttaga aatcgatttg actgtcctgt tcttatttca ttttactata tcttaacaga
      541 tagtgtaaat aaagataaac tatttactgg ctaattaatc agttaaacac tagttaagga
      601 gtaatgatga aaaaaagaac aatactatta ttgatggcca gtctgttagc tcttgtctta
      661 ggagcatgtg gtttcttgga catattgatc ctggatcatt ctcatcagga ttactcttta
      721 ctgctatttt agaaactggg gtggtttgat ggaaagtatt ggtattggtc ttgttatcgt
      781 ttcacattcc aaacacattg cagaaggtgt tgttgaactg attagtaaag tagctaaaga
      841 tgttccgatt acttatgtag gaggaaccga gggcggagga attggaacga gttttgatca
      901 agtagatagg gttgtttccg aaaatccagc agatacttta cttgcctttt ttgacctagg
      961 ttctgctata aaatgttaag taaatgattt caaaatcaga aagggattgc tttgggcagt
     1021 tcctttttaa tgtaaatgta aaaggagtag aatcatagtg tttctaaatt gtgaatcaat
     1081 caaaactgat tgtgatgggg ctattctagc tttagaatcc ttcaaaaatt aaaatttaag
     1141 gcaatcaatt acttggaaga gtatgaaagc atttagttta taggaattct aggcctagaa
     1201 ttacatatgt atttatgaag ataggggtgt tcgatagtta gtattgttct gttctgaaag
     1261 atttgagctg tcagttgtat agaaagtgtt cgaatttttt ttaagtgatt aaattagtta
     1321 attgtatgag gttctttatg atataatgtt cttaatgaat tttcagaaag gaaaacctca
     1381 aattgttcta caaatttcta ctcttcgacc tcgaccacac tcttcttgat tttgatgctg
     1441 ctgaggatgt ggctttgacc caacttctaa aagaagaagg agttgcggat attcaggctt
     1501 ataaagatta ttacgttcct atgaacaagg ctctctggaa agacttggag ctgaagaaaa
     1561 tcagtaaaca agagctggtt aacacgcgct tttctcgttt atttgctcat tttggacagg
     1621 aaaaagacgg tagttttctt gcccagcgtt accaatttta cctcgcccag cagggacaaa
     1681 cactatcggg cgctcatgat ctcttggaca gcctcattga gcgtgattat aacttgtatg
     1741 ctgcgacaaa tggcattact gccattcaga caggacgttt ggctcaatct ggtctagcac
     1801 cttatttcaa tcaagtcttt atctcagaac agttgcaaac tcaaaagccg gatgctctct
     1861 tttatgaaaa gattggccag caaattgctg gatttagtaa agaaaagacg ctgatgattg
     1921 gagattctct aaccgccgac attcaaggtg gcaataatgc ggggattgat actatctggt
     1981 ataatcctca tcacctcgaa aatcacacac aagcccagcc gacttacgaa gtctattctt
     2041 accaagactt gctggattgt ttagataaaa atattcttga aaagatcaca ttttaaagga
     2101 gacgagctaa tgactacaaa aaagctaata ttactattga agagtacatt gaaatgtctg
     2161 aagttgattt taatgaagct gttaattatg aatttacatc tgacacttgt caattagcaa
     2221 atagtattta tcaatctctt tttaagtttt ttgataagaa aaatttctct ggcgatttaa
     2281 tttttacttg gaaatctcca tcattagtca aagaagggga ttatattggg agaagggatt
     2341 cacaagtaga taatcttaga gtaataggaa atatatttcc gaattatctt actaatcgaa
     2401 aatatagcct caatatgaat cgtaatggct gtatgggaga ttttcctcat gacttttttg
     2461 atatatacct agatcatgta gcaaaatatg cctacgaaca aaaagttaat aatattaaag
     2521 agtattatcc tttaaaaaga gcgattttac accaagagaa tgcattgtat tttcgatttt
     2581 tttctaattt tgacgacttt ttagaaaaaa attatttaaa gactatatgg caagtttcta
     2641 aagaaactcc tttttctgaa atggatttta atatgtttaa aaatatttca gaaaagataa
     2701 tcttcgaaag aggtagtaaa atgcttaatg atttaaaaag taattataaa aaatagccag
     2761 tctttataaa ctgtattcac gtattcaaat cgtatatagt cgatttatta aatctttaga
     2821 taaactgtaa aaagtggttt ccatagccac tttttgctat aatagaggca gtaaaaatga
     2881 aggagtcggc tatggaacac tcgtcttggc atgctttgat taaggcgcaa ttacctgagg
     2941 gttatttcgg gaaaatcaat cagtttatgg agcaggtcta ttctcagggg attatttatc
     3001 cacccaagga aaaggttttt caggctctct tgacaacact gcttgaagaa gttaaggtgg
     3061 taattctagg gcaagacccc tatcacggac caggtcaagc gcagggcttg agtttttctg
     3121 tacctgactc tatcccagct ccaccatcct tgcaaaatat cttgaaagaa ttgtcagatg
     3181 atatcggagt taagaaatct catgatttga cagcttgggc tgagcaagga gtcttgcttc
     3241 ttaatgcttg tttgactgtt cctgctggac aggccaatgg tcatgctggt caaatctggg
     3301 agccttttac tgatgctgtg attcaggtgg tcaatcatct agatagacca gtcgtttttg
     3361 tactctgggg agcttatgca cgtaagaaga aggccttagt taccaatcct catcacttga
     3421 ttatcgaatc agcccatcca agtcctttgt cggtttatag aggattttgg ggttccaagc
     3481 ccttttccaa ggccaatgca ttcttaaaag agacaggaca agagccaatc gattggctta
     3541 gataaggaga aaatatgcct cagttagcga cgatttgcta cattgataat gggaaagaac
     3601 tgctcatgct ccatcgtaat aagaaaccca atgatgtcca tgaagggaaa tggattggtg
     3661 tgggtggtaa gctagagaga ggagagacgc cccaggaatg cgcggcgcgt gaaatccttg
     3721 aagaaacagg gctcaaagcc aagccagttc taaaaggtgt catcactttt cctgaattta
     3781 caccagattt agactggtac acctatgttt ttaaggtgac ggagtttgag ggcgacttga
     3841 ttgactgcaa tgaggggacg ctagaatggg ttccctatga cgaggttttg agcaagccga
     3901 cttgggaagg tgaccacacc tttgttgagt ggcttttaga ggataaaccc ttcttttcag
     3961 ccaagtttgt ttatgatggg gataaattgt tggataccca agttgatttc tatgaataaa
     4021 ggagaaagca gatgctacta atcaaaaatg gtcgtgtaat ggatcctaag tctggtttgg
     4081 atcaagtttg tgatgtctta gttcaagatg ggaaaattat caaaattgcg cctgagatca
     4141 cggaagaagg agcagaaacg attgatgcta ctggtcttgt ggttgctcct ggtttggtcg
     4201 atattcatgt gcatttccgt gaacctggtc aaacacataa agaagacatt catactggtg
     4261 ccctggcagc cgctgcaggt ggttttacta ctgtcgtcat gatggctaat accagtccaa
     4321 ccatttcaga cgtggagact ttgcaagcag ttctccagtc agctgccaaa gagaagatta
     4381 atgtcaagac agttgcgacc attactaaaa actttaatgg taaaaacttg actgacttta
     4441 aggcgctctt agaagctggt gcggttggtt tctctgatga cggtattccg cttgagagca
     4501 gtaagattgt caaggaagcc atggaggaag ccaaaaaact caataccttt atcagccttc
     4561 atgaggaaga tccaggtttg aacggtgttc ttggctttaa tgaaaatatt gctagagaac
     4621 atttccatat ctgcggtgct actggggtgg ctgagtacgc tatgatggcg cgtgatgtca
     4681 tgattgccta tgcaactaaa gcccatgttc acatccagca tttgtctaag gaagaaagtg
     4741 ttaaagtagt ggagtttgct caggggttag gtgcagaagt cacagcagaa gtagcgccac
     4801 agcatttctc taagacagaa gcacttcttt taacacaagg tagcaatgct aagatgaatc
     4861 caccgcttcg tttggaatca gaccgtcgtg ccgttatcga aggtctcaaa tcaggtgtca
     4921 tcacagttat tgcgactgac cacgcgcctc atcatgtaga tgaaaaaaat gttgaggata
     4981 ttaccaaagc gccatctggt atgactggct tagaaacatc cctgtctctc ggcttgacct
     5041 atttagtaga agctggtgag ttgagcttga tggaattact tgaaaaaatg acatacaacc
     5101 cagccaagct ttacaacttt gaagcaggtt acttggctga gaatggtcca gcagatatca
     5161 ctatttttga tgccaaggct gaccgccttg tggactccca ttttgcttcc aaagcagcta
     5221 attcaccatt catcggtgaa accttaaaag ggcaggttaa atataccatc tgtaagggac
     5281 aaatcgtcta tcaagcttga taggagttag aatatgaatt attttcgaaa acgtagggag
     5341 agacaagcga aatctaatag tggaatttac tgtcccgcag ctaatcgttc caaaattcaa
     5401 tatgaaacta aagaaaaagc tgaccatgcg gttcaatatg ataacggagg tttagttaga
     5461 agctattatt gtcgtacatg tgcgtgttgg catactactt caaaatctaa taaacctccg
     5521 ctaagtttga aaaactatgg tctgaaactc tttggtttag ataaatcaga atagaaagag
     5581 aagtatgtat aagacaaagt gtttacgaga gaagttagta ttatttttaa aaattttctt
     5641 cccaatcctg atctaccaat ttgccaatta ttctgcctct tttgttgata ctgcaatgac
     5701 aggtcaatac aacactatgg acttggctgg tgtatctatg gcaaccagta tctggaatcc
     5761 tttctttaca tttctaacag ggattgtgtc agccttggtg cctatcattg gtcaccatct
     5821 tggtcgaggc aaaaaggaag aagttgcgtc tgatttttac caatttattt atttggcctt
     5881 gggcctatct gtggtcttgc tggggatggt acttttcttg gcaccaacaa tcttgaatca
     5941 tattgggtta gaagcagcag tagcggcagt agcggttcgc tatctttggt ttttatctat
     6001 cgggattatc cccttgttgc tctttagcgt cattcgttcc ttgctggatt cgctgggctt
     6061 gaccaaactg tccatgtacc tcatgctttt gttactccct ctcaatagcg gatttaacta
     6121 tctcttgatt tacggtgcct ttggtgttcc agaactggga ggggctggtg ctggtttagg
     6181 aacatccttg gcctactggg tcttgcttgg gatttctgtt ctggttttat ttaaacagga
     6241 gaagctcaaa gccttacacc ttgagaaacg aattccactt aatatggata aaattaagga
     6301 aggagttcgt ttaggtctgc ctattggggg aactgtcttc gcggaagtgg ctatcttttc
     6361 agtggttggc ttgattatgg ctaagttttc gtccttgatt atagctagtc accagtcagc
     6421 tatgaacttt tcaagtctta tgtacgcctt tcctatgagt atctcatcgg ctatggctat
     6481 tgtcgtttcc tatgaagtgg gagccaagcg atttgatgat gcgaaaacct atattggtct
     6541 aggaagatgg actgccctca tttttgcggc cttcacctta accttccttt acatttttag
     6601 gggaaatgtg gccagtcttt atggtaacga cccaaaattt atcgatttga cagcgcgttt
     6661 tttaacttat agtcttttct tccagttagc agataccttt gcggcgccgc ttcagggaat
     6721 tttgcggggg tataaggata cagttattcc tttttacctt ggtttgcttg gttattgggg
     6781 cgtagcaatc cctgtggcta cgctatttga ttccctaaca gattttggag cttattctta
     6841 ctggatcggc ttgattatta gtttgattgt gagtggggcg ctctaccgtt ggcgtttaac
     6901 tgtgattatg aagagatttg aatctttagc aaaatccaaa cgctaaaaag tttgtgaaaa
     6961 aatattcttg ataagaaaat cccttgtttt cacggggttt tcttttttat tttgtgaaat
     7021 ttcttttaga aaaactttga cagtatttgc caaaaacggt aaaatagtaa ggtaagaaga
     7081 aagttagaaa ggcaagaaga tgtcaacttt agataaaaat cttttgctag aaatgttccg
     7141 taagatggaa gaaatccgtc gcatggactt aaaaattgca caattagtaa agaaagggaa
     7201 agtgccagga atgacgcact tttctgttgg tgaagaggca gctaacgtgg gggctatgtt
     7261 agctctcaat ccagatgatc tgattacctc aaaccaccgt ggacacgggc aagctattgc
     7321 taaagggatc gacctcaacg gaatgatggc tgaaatcctt ggtaaataca ctggaacctg
     7381 taaagggaaa ggtggatcta tgcatatcgc tgaccttgat gctgggaacc ttggtgccaa
     7441 tggtatcgta ggtggtggta tggggatcgc tgtcggtgca gccctcagtc agcaaatgca
     7501 aaataccggt aaaatcgttg tctgcttctt tggagatggt gcgaccaatg aaggtgtttt
     7561 ccacgaagca gtgaacatgg cttctatctg gaacctgcca gtcattttct attgcattaa
     7621 caacggttac ggtatctctg cggatatcaa gaaaatgacc aatatagaac atatccatca
     7681 acgtagcgcc gcttatggaa ttcctggaat gttcatcgaa gacggtaaca atgtcatcga
     7741 tgtctatgaa ggatttcaga aagctgtaga ccatgttcgc agtggcaatg gtccagtctt
     7801 gattgaaagt gtaacttatc gctggctcgg tcactcatca tctgaccctg gtaaatatcg
     7861 tacgcgtgaa gaagtggaat tgtggaaaca aaaagatcca atcgaaaacc tccgcaatta
     7921 ccttattgaa aataacattg caagtgccga agaattggaa gaaatccaag cgcaagtaaa
     7981 ggaagcagta gaagcttctg ttaaatttgc agaggaaagc ccattcccac cgcttgaatc
     8041 agcctttgaa gatatttacg cagactaagg agaaagagat aaaatggaaa caaaaacaat
     8101 gtccttccgt gacaccatta tccttgctat gtctgaggaa atgcgtcgcg atgaaaatgt
     8161 gttcttgatg ggagaagacg tcggtgtctt cggaggagac ttcggtactt ctgttggaat
     8221 gcttgaagaa tttggtccag aacgcgtccg tgactgtccg atttctgaag ctgccatctc
     8281 tggagcagca gcaggagcag ccatgacagg acttcgtcca atcgtcgata tgaccttcat
     8341 ggacttctct gttattgcca tggacaatat cgtcaaccaa gctgctaaaa cacgttacat
     8401 gtttggtggt aaaggtcagg ttccaatgac tgttcgttgt gcagctggta acggagttgg
     8461 ctctgccgcc cagcactcac aatctctaga gtcttggttt actcacattc caggacttaa
     8521 ggttgtggca cctggaacac ctgcggacat gaaaggcctg cttaagtctt ctatccgtga
     8581 taaaaaccca gttattatac ttgagtacaa gtcagaattt aaccaaaaag gggaagtgcc
     8641 agttgatcca gactacacaa ttccacttgg ggttggtgaa atcaaacgcc aaggaacgga
     8701 tgtaacagtt gttacttatg gaaaaatgct tcgccgtgtg gttcaagctg ctgaagaatt
     8761 agcagaagaa ggaatttcag ttgaaattgt tgacccacgt acccttgttc cgcttgataa
     8821 ggatatcatc ataaactcag tgaagaagac tggtaaggtt gttctggtca acgatgccca
     8881 caaaacaagt ggctatatca gtgaaatttc agctattatt tcagaatcag aagcatttga
     8941 ctatctagat gcaccaatcc gccgttgtgc aggagaagat gtgccgatgc cttatgcaca
     9001 aaacctagaa aatgcaatga ttccaacagt tgaaagtatc aaagatgcaa tccgaaaaac
     9061 ttataacaaa gaatagagtt acataagata agttatgtaa ataaaataaa gctgacgaga
     9121 aactttgtat cttttaggtg cagagctctt cgtcattaat atcttatatt cgagcacggg
     9181 ctaaaagctc ggaaaaaaga taaatctcct tggcttcatc gaagccatcg tcgatttcct
     9241 atttttcagt cgcttttgac gccctttgta tcataaatag aattggagag gtcatggctg
     9301 atgacaagct aagagcgact cctgcagcta gaaagttagc ggatgattta gggataaacc
     9361 tctacgacgt ttctggctca ggtgcaaacg gtcgtgtcca caaagaagac gtggaaactt
     9421 ataaagacac aaacgtggtt cgcatttcgc cacttgcaaa acgaattgcc ctcgaacata
     9481 acattgcttg gcaggaaatc caaggaaccg gtcatcgtgg taaaatcatg aagaaggatg
     9541 ttttggccct gcttcctgaa aatatcgaaa acgatagcat caaatctcct gctcagattg
     9601 aaaaagtgga agaagtccct gataacgtaa caccatatgg tgaaatcgag cgtattccaa
     9661 tgacaccaat gcgtaaggtt attgcccaac gcatggttga atcttacttg actgcgccaa
     9721 ccttcaccct caactatgaa gttgatatga ctgaaatgtt ggctcttcgt aagaaggttc
     9781 ttgagccaat catggaagca actgggaaga agactactgt aacagacctt ctttcgcttg
     9841 cagttgttaa gactcttatg aaacacccat acatcaacgc ttcattgaca gaagatggca
     9901 agactattat cactcacaac tatgtcaatc ttgccatggc agttgggatg gataatggat
     9961 tgatgacacc tgttgtttac aatgctgaga agatgagtct ttcagaacta gttgtagcct
    10021 ttaaggatgt tattggccgt accttggatg gtaaattggc tccaagtgag ttacaaaatt
    10081 caacattcac aatcagtaat ttgggaatgt ttggtgttca gtcctttggc ccgattatta
    10141 accaacccaa ctcagctatc cttggtgtca gttcgacaat cgagaagcca gttgtcgtca
    10201 atggtgaaat tgtgattcgc ccaatcatga gtttaggatt aaccattgac caccgtgtcg
    10261 tagatggtat ggctggtgct aagtttatga aggacttgaa agagttgatt gaaaccccaa
    10321 tctcaatgtt gatttaagag caagagtatt catttttaag atatagataa aggaaggaag
    10381 acatggcctt agaaataatt atgccaaaag ccggcgtgga tatgacagaa ggacaaatcg
    10441 tccaatggaa taaaaaagtc ggagaatttg taaaagaagg agaaatcctt ttggaaatca
    10501 tgactgataa agtcagcatg gaattggaag ccgaagaaga tgggtacttg attgccattc
    10561 tcaaaggaga tggtgaaact gtccctgtaa cggaaattat cggttacctt ggtgaagaaa
    10621 gggaaaacat cccaacagct ggagcagcat cgccagaagc tagccctgta cctgtagcaa
    10681 gtacctcaaa cgatgatggt aagagcgatg atgcttttga tatcgttgtg attggtggag
    10741 gtcctgctgg ttatgttgca gccattaaag ctgcccaact cggcggtaag gttgcccttg
    10801 ttgagaaatc tgaacttggt ggaacctgct taaaccgtgg atgtattcca accaagacct
    10861 accttcataa cgctgaaatt attgaaaata tcggtcatgc tgcaaatcgt ggtatcgtga
    10921 ttgaaaatcc taacttcact gttgatatgg aaaaactttt agaaactaaa tctaaagttg
    10981 ttaatactct tgttggtggt gttgcaggac ttcttcgtag ctacggagtt actgttcata
    11041 aaggaattgg tacaatcact aaagacaaga acgtcttggt aaatggttct gaattgcttg
    11101 aaaccaagaa aatcattctt gctggtggtt caaaagtcag caagatcaac gtccctggta
    11161 tgcaatctcc acttgtcatg actagtgatg acattcttga aatgaacgaa gtgccagaaa
    11221 gccttgttat catcggtggt ggagttgtcg gtatcgaact cggtcaggcc ttcatgacat
    11281 ttggttcaaa agtgactgtt atcgaaatga tggaccgtat agttccagct atggatgcgg
    11341 aagtttctaa gaaccttcgc ttgatccttg agcgtaaagg aatgaccatc ttgactggta
    11401 ctaaactgca agaaatcatt gaggaaaatg gtcaacttcg tatcaaggtt gaaggaaaag
    11461 acgatatcat cgcaagcaaa gctcttcttt caattggtcg tatgccagac cttgaaggta
    11521 ttggagaggt tgagtttgaa ttggatcgtg gttgtatcaa ggtcaacgaa tacatggaaa
    11581 cttcagttcc aggcatttat gcaccaggtg acatcaacgg tactaagatg ttggctcacg
    11641 cagctttccg catgggtgaa gtttccgctg aaaatgccct taaaggaaat catgcagttg
    11701 ccaaattgaa tttgactcct gcagccatct acactctccc tgaagtagca gcagtaggtt
    11761 tgacagaaga acaagcccgt gagaaatacg atgttgccat cggtaagttt aactttgctg
    11821 ctaacggtcg tgctattgca tctgacgcag ctcaaggttt cgtaaaagtt atcgctgata
    11881 agaaatacgg agaaatcatt ggtgtacaca ttattggtcc tgcagccgca gaattaataa
    11941 acgaagcatc aagcatcatc gaaatggaaa tcactgttga ggaaatgctg aagaccatcc
    12001 acggacaccc aacttactct gaagtgatgt atgaagcgtt tgcagatgtt ctaggaatgg
    12061 ccatccattc acctaagaaa aaataaaacg aagatagatt agactggaag gttatttcca
    12121 gtctctatca tataaagtaa agggatatca tgaaatacat tatcaatcat tcaaatgaca
    12181 ctgcttttaa tattgccttg gaagaatacg cctttaaaca ccttttggat gaggatcaaa
    12241 tcttcctact ttggattaac aagccatcta tcattgttgg tcgtcaccag aacactatcg
    12301 aagaaatcaa ccgtgattat gttcgcgaaa atggtattga ggtagttcgc cgtattagtg
    12361 gtggtggagc tgtttaccac gatttaaata acctcaacta cacgatcatc tccaaagaag
    12421 atgaaaataa ggcatttgac ttcaagagct tctcaactcc ggttatcaat accctggctc
    12481 aactcggggt taaagctgag ttcacaggtc gtaatgacct tgagattgat ggtaagaagt
    12541 tctgtggcaa tgcccaagcc tatatcaacg gccgtatcat gcaccacggt tgcttgctct
    12601 ttgacgttga tttgtcagtc ctcgcaaatg cccttaaggt ttcaaaagat aaatttgaat
    12661 caaaaggtgt gaaatccgtc cgtgcccgtg taaccaatat tatcaatgaa ttaccaaaaa
    12721 aaatcacagt cgaaaaattc cgtgatttac tcttggaata catgaaaaaa gagtacccag
    12781 agatgactga atacgtcttt tcagaagaag aattggccga aatcaatcac atcaaggata
    12841 ctaagtttgg aacttgggac tggaactatg gtaaatcacc tgaatttaac gtccgtcgtg
    12901 gaaccaaatt cactagtggt aaggttgaag tctttgctaa cgttactgaa tcaaaaatcc
    12961 aagacatcaa gatttatggt gacttctttg gtattgaaga cgttgctgca gtagaagatg
    13021 tccttcgtgg ggtgaaatac gaacgcgaag atgttcttaa ggcgctaaaa accattgata
    13081 tcacacgcta cttcgctggt attagccgtg aagaaatcgc tgaagcggta gttggataaa
    13141 tcaaaaaaag aagttggcca acttcttttt ttgatattta tttacataat ttaaaatacg
    13201 tgaaatcata aactatctag agcattcttt tgttcatcat taacaatatg ggtatagagg
    13261 tcagtgactt gtgtgctggc atgtcctagt tggtgactga ctaaaacttg tgatttagtc
    13321 gcatcataga gcctagttgc tagcgtatgg cgcagtttat ggggtgttac acgtacttta
    13381 aaatcctctg agtatttagc aaccattttc tcaacgctag aagcatcgat acgattagga
    13441 acacctctgt agagagttaa aaaaagggct gtatctgttt tttccgtttt atagcgttga
    13501 ttccgaatgg ccagataatt ctctaaataa ggtttagcaa aagcagcgac attgactgag
    13561 tcacgtttgc caccttttcg agtaacatca ataaccatca tttttagatt gagatctctt
    13621 agatctagat taacagcttc agataagcga acaccagatg ccaagagaag ggcaataatg
    13681 gctaaatctc gttctttatt tttgttgaat gatgagagag ctcgatttga aagctgttgt
    13741 gggtgctctt gatcgatata agttagaaaa ccttctgttt catcacctag aaagagtttt
    13801 tgcttgatat tttcagctct ggcagcaagg gtttctttct ttttcttggt tgaaactttt
    13861 ttcattacat tacgatagaa ataaggttcc ccctgatcgt tttcaacctc ctcggttaga
    13921 tacttgtaaa gactagaaag tgctgataag gttcgattga tagttgtctg tgaaacacct
    13981 tgttttgttg tattagcatt cagcaaggga cgttcacgta gataaaggat aaaggattcc
    14041 atgtctttct tagacatatt ttccaaaact gataaaggaa tatcggatat tttatcagcg
    14101 tttgaaatac cagactccaa aacccagctg aaaaatcggt catattcctt aaggtattcg
    14161 tacagggttg taaaactgta gggcacagcc agcttagatt ggtagtattc cagaacatac
    14221 cagggcatga gttgttttag tttgtcgatt cgttccagta aaatctcacg tttcatgtat
    14281 tttctccata agtaagtata ctagtagtat agcatagact tgtatatttt tcaagaaaat
    14341 tatagttttt cagaaagatg ttataggagt ttttcaaagt gataaaaaga cttagaccta
    14401 caaacaaaac agaataagga aaataataaa aatctcaccc actaaacttc tgttaatact
    14461 acataactga agagctatat aaggagctat gagatacaaa acacattgta taatagattg
    14521 aaactagaat agtacatctg gacttctaaa acattgctag aaattgattt gattgttctg
    14581 attgttttat cctatttcta tttcatttca ctatataatt gctattgttt tctttttcat
    14641 gattttaatc ttactgtaca gatttgatac agtaaactcc tttctagctt tatactttat
    14701 catttctaac ttaattatag tcttattttt aataaagttc aattatttat atgtaaaatt
    14761 cctcatcagt aaaaaataac cgatctcatt tctgagaatc ggttttctaa ataaatcaag
    14821 ctgagtattt acataacata aattatgtaa atactcatac tacaacaaca aatctttgac
    14881 ttttccaatt tcactttttg gaataaccag gtgaatcata tcacccagat acattctggt
    14941 tgagccgtta actgtttggc tcttgccatt atggacttga gttgtgatga ggacgttgtg
    15001 tggtaagttg agttcatgaa cttgtttccc agcaatttta tcagaaactg gtatttcgat
    15061 aagtgtaact tctccttcgc tagatacttc ttctggaagc attttttcca gcatggcttc
    15121 atagactggc gtacctttga gcaaatccat gataatataa gaaacaagag tgacaagacc
    15181 aagtggcatg aggttgcgaa tatctcctac catctcagtt acgaggatca tagcggttaa
    15241 gggagctttt gatatggctc caaaatagcc actcattcct agaatgacaa atatagggaa
    15301 ttgctcttga ctgacaagtc caagattgac acagataaca ccaactaagg aaccaagcaa
    15361 agaaccaaga gctaaaatgg ggaggaaaat tcctcctggc agtccacttc catagctaat
    15421 catactccaa ataaagcgga tcaaaaagta agctaataaa acttggaaac taaaattttg
    15481 ttcagttaaa gaaaggacaa gctgatttcc gccaccaatg atttgaggta agaagattcc
    15541 gactggtatg ataatgataa aagccaagat gggataataa gccctatcca aatggatttt
    15601 ttgaccaatc aagtcataaa ctcttccaac gtttaataca gctttctcat agagaaaacc
    15661 tgaaaatcca aggaaaattc ccatgacgag atatatccaa tactggtcta gggtcatggg
    15721 aggaatgtta tctggcatat ccaatactgg tgtcaaaccg aacatgagta gagacacaaa
    15781 gtttgctacg atgctggctg ctagagttga gacccagaaa aagcgcgaaa aatggtgata
    15841 gacttcttct acaacaaaga gaagtgctgc aataggagca ttaaaggctg cggctaaacc
    15901 tgctgcagct ccactggcaa tcaaggaacg ttcctctact ggactggatt tgagccactt
    15961 ggcaattcct ttaccaccaa ctgctccaag ttgaatgctg ggtccctctc gacccagcat
    16021 gagtccactg gcaatagcaa gaatacctag cacatatttt ttccaaagaa tgccccacca
    16081 gttgagggac atgaggcctt tcagttcggc ttcgacttga ggaattcctg agcctttaat
    16141 atctttttct gaccgtgtta gtttggcact gagccaacag atgagtatat aaaacaaaac
    16201 cagtacaaaa agattgcgca ctaagtaccc ttgatcttga taaactcctt gtatcaggtg
    16261 gaagcccttt tcaattaaga aacgaaagga tccgacgata attccaacga tgaggccgac
    16321 aatgattcct cgaccaactt gggatagtat agtgctggat gcaaaggcga attctttctt
    16381 agaacggact atttccgact gttcctccat ggtatttcct ttcaattaac tttctttttt
    16441 acctaaaacc agtgatttaa cgggttcaaa gctggttcgg tgaattgggg taactcctag
    16501 ttttgtgagg ccttccagat gtttagctgt gccatatcct gcattagtag cgaaatcata
    16561 gccagggaac tgctgatcgt attccttcat caattcatca cgtgttacct tggctactat
    16621 agatgctgct gcgatagaga gggagttggc atctcctttg ataatggagg tttgtgaaat
    16681 gggcaagtcc agtttcatgg catcaatcaa aaggtgctct ggttgagggc tgagctggga
    16741 gattgcttct tgcatggcta gtttggttgc ttcatagata ttgacttggt cgatgacctg
    16801 attatctatg ataccaattc caatcgacaa ggcttggtct tgaacgactt ggaaaatctc
    16861 cagatgtttc tttttaggaa ttttcttgct gtcgttgaga cctttaatct tacaattttt
    16921 aggtaaaata acggccgcag cgactacagg accagcaaga ggaccacgac caacctcatc
    16981 aatacctgca attaaggtca atccttgctt ataaagttct ttttcataag aaagcatgga
    17041 ttccaagcgc aaattttcat ctaattcagc ttgaatggct cttttatgct tgctgatttc
    17101 cttttgaact cctgagcgat tatccttttc aagatctaaa aaaatagggc tttctaactc
    17161 cttgactgtc acaaggagtt ctttgatttc tttaatcgtt gccatcgagg ccttccaatg
    17221 tatctaaggt atagttaccg agtttgccat cacggacttc cttcacgaag agactgtaaa
    17281 aacggtcata gtcatcacgg aaaccgaggg cgcgggtcat atccataata atcacaggcg
    17341 cttcttcttc aattttcatt tgtttgaagc gttcagccag cttttctgga taatgttctt
    17401 tgaaataatt gataccaaaa atggtaacct catccatagg aagcaactga tccttgatag
    17461 ctccagtcaa tgccaactta agtgcaacag tttcatcctc aaacttaggc cagagaatcc
    17521 ccggtgtatc caagatttcc agatctttat tggttttaag ccattgttga ccttttgtga
    17581 cccctggctt gtttccaaca acagcaatct ttttaccagc caaacggttc atcagagttg
    17641 atttaccagc gtttggaatc ccaataatca tggtacgcaa ggtttcaatc tgaatcccac
    17701 gttctttctg gcgagcaatc ttatcagcca tgagcttctt ggccgcatct gttacaactt
    17761 ttacagtcac ttgctctttg gagttgatag ctagcgtctg gattccttgt gattcaaaat
    17821 actgacgcca ttccttggtc attgctggat cagccaagtc ggccttgttt aaaatcaaga
    17881 gttttggttt atcaccaaca atcttggtta acataggatt ttgactagat agaggtaagc
    17941 gtgcatcaac taaaatcgtc acaaaatcaa caaattttaa attctcctgc acctgtcgac
    18001 gagctttaga catgtgacca ggaaaccatt gaatagtagc cattgagttt tttcctttca
    18061 tagcaaggat ttagatcccc tattttattt tactattgtt tgaacataga gagttttcaa
    18121 atgaatgatg tccaaacagt tcttgtttta tgacatagaa atctacttta tattatatca
    18181 tgccttcttt attttgtccg atgatagcct tttaccctat atagaaaaaa gccatcaaat
    18241 gatgactttt cagagggagc aaaaaactgt tcccgtcata ttatgaacca aaagaactaa
    18301 actaccaaca gctaataggc ctaaagctgt aagtgcagaa gttgatgaac ctgttgcagg
    18361 aagagtttcc tgctgataaa taagagcata acttacttca ttatcagtag gaattcctgc
    18421 ttgaatcttg gtttgttctt catcaccttt ttaaacttta tttcctaata gtaaacacta
    18481 ttttttattc tcaaaaattg aacttctaaa atcatttgtt tggtcaagat aggctttaaa
    18541 gattgctctc ttcaacttat gaacggcact gtcgatttct ggatcataat tactccaacg
    18601 tggaccttca gcatccttga gaacagcttg gtccatgagg gcttgcaatt catccacatt
    18661 attgatagtc tttgtgccat agcttggcca tggttttgtc ggatctttaa aggtcacctg
    18721 cttcaagttt ccaaactgat ccactcgttc ttggtacata gctgtcttaa attctgccca
    18781 agttttatac ttaccgtcaa ataccttttt caaaacaagc tcatcggtca ccaagccccg
    18841 ttctttacca taaagattga tagtttgccc ttgttgttta gcatcttctt cgtattggtt
    18901 tgagatataa ggtaccattc catccttaaa gcctttggca gccaaaagtt cgtacgcaat
    18961 cctacgtccc ataaggtccc ctggtgtgcc tttctcactg ctgagagctg aatagattgg
    19021 ggcaaagagt ttgatggtat agtagccatt tcgttcatag tcgccagact ggtactcacg
    19081 agctgataag atgttgtggt caatcaaact ttcaaaacta ttcaggtttc gggcctctgc
    19141 ttctgtcaat tctttgacta cgttagtggc ataaacctca tttccatctg ctggatcttt
    19201 cacatacttg ttctcaattt ttctgagagc cgccattttc tggtaaacac ttagtttatt
    19261 aacgattgac tgcccttcga gatattccat catgtagata aggtcaaaca tgttatggac
    19321 atagttctga agatctgctg cgttttggaa tctctctgtc ggatccaaga cttgaagacg
    19381 ggatccctct gtactatctg attttgagtg tttcaagata gaattaatgg taatggttgc
    19441 gtcacttggt tggtcagggg cttgcaataa gccttttgcg aagaactctg gtcccaagcc
    19501 atttcttcga ccatagccac caaggtaaat atcctgatcc gaatcatggg tcatttcatg
    19561 ggtataagta atggctccat ccttgtccag catgcggtaa gacatatagt agacgccgtc
    19621 ccctgtagcg taggctccat gctggttgtg tactacctta ttgccaactg gtccaaagaa
    19681 gttcttcata gctggattgg agctatcaaa cttagcctcc gctgtagctt ttcctgatgt
    19741 tgtgtcatcc ccaaacttat aggcatcata aaggagaatc gtacgataga gtttttcgcg
    19801 tgactgttca tctaaaatac gataccaata atcgtagtga tctcgctgac gtttggctgt
    19861 ttcacgcgca ttttcttcaa caaaatcatt gagagccttg cccgctttat ggtcactact
    19921 gcggtagcga tcataagctc caaatcctag actagacatg gtcgagatga caaatacgga
    19981 tctctctggc aaggtcagga gaggcaagac catattgcgg tatttccatg tggcactcgt
    20041 gatacgatca taaacaccga tagaatactt ggtgccagct aacccttgct tcgttttcac
    20101 ctcttcgata gtggattttt cttcgacaat gtaagcctta gtctctgatt taaaccagtc
    20161 attattgctt gtatttggta aaaagacttt tcggtaatgt tccagcgtgc taaacaaatc
    20221 tgtcgttcca tgttgactgg caagactgat accataagta tcgacattat tcttagctag
    20281 aagattgtta aagccagatt tacctaactc aatcagagta tctagtgggg aagtatttcc
    20341 tttaccaaag aagtctggat gatacataac taggtctttg acattcactt gaccatagtt
    20401 aaagttatac caacgttcta aataagttaa accgagtagc aaggcttcct tattattctt
    20461 gattttatct acaagatagc ctctggtgac tgagttatcg ctagctagac cggcatctgc
    20521 tgacaaaagt tttttcaagc tgtctcccag attttgtttt gttttggaga actggtcttc
    20581 taaatagagc tcggttaact taacttctgg agaaatacca agtgtctttc tgatagcatc
    20641 tgactggtaa tcaagcttct gcaactcagg caagacttcc ttaacaatag agtctcgatc
    20701 atataagaat tggttaggag tgtagagaag tcccgtatta cctagattat attctgctag
    20761 attggcaaaa tcagtctggt acttgagatc aaatttctca gatgaatggt cattatagtg
    20821 aagtaagagt ttgtttgcag tctgtttgtt ggaaacaata tctgtgatta cttggtcatc
    20881 cttcatcata actgcagata agagttcttt ttggtataag agactgttct ccttaaccag
    20941 gtttccgtat ttgacgatgg ttgacttatt ataaaaaggt aacaattttt caatgttctt
    21001 ataaaccaaa gcacggttag cttgataatg ggctatctta gaaaaatcac tgtctttctt
    21061 gccacttgtt gagaggggtt ccaccgttgg tagagtgaga ggatttattt ctgctttttt
    21121 gcttacaatt tgagaagcat ctagcattgt tcctctttct tcaaaggatt ccttgctgac
    21181 gacctcatcc ttctctaaag tgacattgaa aactctatta gccttactac taaatgtatt
    21241 agctaccttc attcctgtat agtggtatcc agtgatggca tttccgtttg ttacattgac
    21301 atcgctaaga acattggtca attcaccagc gtgtttttcc tcaccagaag ttcgatccca
    21361 caaatatcct gccacaccag cgactttacc aaagtgcttg acattattaa tatcaccttc
    21421 cgcataactg ttctgtatat gcgcatcttg gtctactaga cctgcaagac caccgacagt
    21481 ctgatctgac ctattggtgt ttgacgaaat ggttactgtc gctttggatt tagcaataga
    21541 cgcatttttt cctgttaaat gaccgaccag accgccaata ttgtaggcat cagtcgtttc
    21601 ataggtattg acaattcttc ccttgaaact gctctctgcg atgcttgatt ggtctgcctt
    21661 agccaacaaa ccaccgacac cacgttctcc agccagaaca ccatcaacat gaacttgttt
    21721 aatctttgtg ccattcgtag cttcatttgc tagtgaacca atatcatttt tccctgaaat
    21781 agcaacattt tttagactca gtttttctac tgtagcacca ctcaagtttt caaacagagg
    21841 ttttttcaaa ttatagatag cataattctt gccatctttt tcaccgatta aacgaccagt
    21901 aaaggtgtcc ttgatatagg atctttcatc aggaccaagc tccacttcgt tagcattcag
    21961 gctggccgct aaatgatagg ttccagaggg attttggttt atagctttga ccaggttgct
    22021 aaaggaagta aagtttgtat tttcctcttt agccttctta tcgaggtaga aggtgaaatt
    22081 gtcgacatat ttattttcta gttcttgctg gagtttctca gctttggctg tgattttata
    22141 aactgactgc ccatttcttt tctcttcagt tattgaagct actggtatat agacatcttt
    22201 aaatgctgaa gattttacct tgacaaagta agtatccgta ttctctggaa ttccatccaa
    22261 tgaaacatgt tgtctgtagg ttccattcgt ctgactatac aactcaatat cagaaacatt
    22321 tcttaattcg agttttttct ctggttctgt ttgtccattc tctgatgttg tattacctga
    22381 attttctggt tttgttgcag ttccgttttt ttctggttga tttgattctt caactggtgg
    22441 ttttgaatca ctaggtttat tggatacttc tccagtattt tcgttagcta ttttcccaga
    22501 gtttgtttgt gtttcttctg caggttgaac tggtttttct gtttcttgat ttgaggtacc
    22561 ttctactgtg ccttcatttg gatttactgg aacttcttct acagtttttt ctgaattttc
    22621 atttttagag tcattatgtt ctggtttatt tgattctcca actgaggttg tcgaatcact
    22681 aggattactg gacacttccc cagtattttc gctagatgta tctggtgata ctttctctga
    22741 attcgttgtt gattcttctg caggttgaac tggattttct gcttcttgaa ttgaggttcc
    22801 ttctgtagta ccttcatttg gatttactgg tgtttcttct gttggtttta ctggaacttc
    22861 ttcagttttt tctggacctt gttctttggt cttctcaacc ggagtttcag gttttacttg
    22921 ctcaatatta cccttatatt ctggcaatgg ggctacctgc tctggttcac ctttatcact
    22981 taccacagta tctggcgact ctggttgaac ctcagtctca cctttgtcgg tcacaactgc
    23041 ttcgggtaat gtcggttgaa cttctggttc gcctttatca cttactacag cttcgggcaa
    23101 ctcaggctga attgcgggtt caacaataga tccagactgt acgtccttat gttctacacc
    23161 agtctcaggt tgttccttta taacttgagt ttttttagta cctttttcga ctattcttgg
    23221 actaggcgca gtcgttgaag ttgaaacaat ttctcgcgaa acttcttcct tgtttacaga
    23281 gaatattctg acgatttcaa ctttcttacc taatttacct tcttgtttta ctcttacagt
    23341 tccttcagct aaatcaggat tttcttgaat ttcttcttga aaatctattt ttgtctctat
    23401 agtttcctca cgatataaga gttcaggttt gttcaattga cctgataaaa cttcatcctg
    23461 tggatttaat gtatttaccc cagtcttttc ttttggagaa atcttctcct ctttcttcgt
    23521 ttctagattc ttatgttcgg ctaattgttc ttgagaatct gaagattgtt tctcttcttt
    23581 tcttggattg attaattcag tagagaaagg tttttcaact acttgaactt ctgtcggctt
    23641 agttgaagaa acaggtgttt gttcctgaat agcttgtact gttgatggat ggtctacaaa
    23701 atttggtgta acattataat ccaccttttg ttgttttgta ggagtggctg ctgatttttc
    23761 ttgattactt acttcaaaat cagaagtcgt ttttccctct ttgatatatc caatataagt
    23821 gtaacctgaa atctctttag gaagaggtaa tttttctcca gaggtcaatt catagtccgt
    23881 attgtaattt agcaaaagat gattttctaa agcatggact gaaactaaga caccatttcc
    23941 cattcccgca accaatacta aatgtaatac cgttttattc ttaacctttt tcttggaaac
    24001 agcaaaaatt aaaattccca gagcagctaa gctagcacca gcaactaggg cttgcctctc
    24061 attcttgctt ccagtatttg gtaattccgc cagttgattt tgagaattta acttataaac
    24121 aagataataa gtttcatcat cattctccac gtatgtcgga atatcataga caagctgctt
    24181 cttttcttct gatgatagct ctgaatctgc cacatattta tagtgaactc ccgcagtttc
    24241 ttgagcatcc acagatgaac tagctaatac agacataaaa aataaacttg aaatcgttgc
    24301 agatacaagt cctactgata attttctaaa tgaaaaacgc tcttgttttt caccaaaata
    24361 cttttccatt attcctcctt gaaataaaat ttatatatgt tacaaagacc tttattatat
    24421 tagtgtatta tctattatct atagaaaagg cagtatacct taattatact cttaatttac
    24481 aaaaaagtct taaaattgag atgcgctttc atactttgtt ttatattatt tgggggtaca
    24541 ataacaccta ccatgaaatt tacacggtag gtgttactca tatcactaat cgttctaaaa
    24601 atggtttgag gcagttgagg agaattcctt ctatccagct tccttgtgct gatgagcgat
    24661 ggtcttcctg caggcttttt tttagaaaat ctcggacttg ttctggtgcg atttcaaatt
    24721 caaaggcttt cattttatag aaaaagtcga tgagatgatc tgacaggtat tcagttgaaa
    24781 agggtacttc accacttttt cgatattcta ataagagtct agaaaatcga gctttttctt
    24841 caggaagctc acgaaaatag gaattgagga tccaagtctg cttctgtttt ctttcaattg
    24901 gatcctgact ggcaattcgt tggtcttttt ccagctcttt ttggtattgt ttggccttga
    24961 tagctcgttc tgctctattt ttaccaaaaa gaattttttc ccacttgcgt tcttcttgag
    25021 tcagggtctc tgtaaagcca aagtaatctt gataagcacg ctctgcgggt cccatggcta
    25081 gaaccagatt gtctgcatat tgcttggcga ttttatccct cttcttgcgt tctttctctg
    25141 cctggatacg gagttcttgt tcgtagtcaa ttttctcctt gcctagcttg acaaggtaga
    25201 gttggtcatc cgatttccca agtaaaaagg gtttgataca cttttcaagg acttcttcca
    25261 tccgagcctt tttctttggt tccgccttgg tccaacttcc tccctgaaag acttctagga
    25321 aaagctggta gtctctctca ggcgcaaatt gattgccacg attgggtttg aaaacacctt
    25381 tttcccagag ccattttaga agtcgctcgt caaagtcact tttattgacc ttgatttttt
    25441 cctttttctg agcttttctg gttagatttt caacctttct gagcagtttt tcttcctctt
    25501 ccaattgctg gtcaaggggc aatcgatgaa aatgacgaac acagtcgcta ccaattggaa
    25561 agaggcgttg gcctgtgaca ccgttaaaga gttcataagc gtatttgatg gcatttcgac
    25621 agacacaatt gctacggcca ataccgttaa aaatcaagga aacttcattc cattccttgg
    25681 tagcttgttc ccaagtatcc gctttcgaag cctgtaaaac tgcatcgtgc agggattttc
    25741 taactggaag tgtcatgagg tctcctttct aatactcaat aaaaatcaaa gagcaaacta
    25801 gaaagctagc cgcagtcagc tcaaaacact gttttgaggt tgtagataga actgacgaag
    25861 tcagtaacca tatatacagc aaggcgaagc tgacgtggtt tgaagagatt ttcgaagagt
    25921 ataagttata cttttacaac ttgaacctcg tctttaccga gtaaaatcaa gtatttttca
    25981 atattttcaa tcgaataggc tcgtgataaa gcctcttcgt atagagctaa ctgaccacga
    26041 tagcggtcta cgagttgact tggttcatca tagcggtctg tcttgtagtc gaacagaaca
    26101 attttgtttt cgtaaagcag atagccatca aggataccac ggacaacaaa gtcttcctga
    26161 ctcttttggt ctcgtttgag catggagaaa ggttgctcgc gatagagatg gtcggtatta
    26221 gcaagaattt cctgaccgag tgctgtgtca aagaaagcaa gaattttatc aagattgatc
    26281 ttgtctctga cagcttggct agtttgaact tgtttgagtg tttctgttaa gctagcaagg
    26341 gttagttgct ggctgaggtc aattatctgc atgagttcgt gagtagcact accaatctca
    26401 gctccagtta ccttttcttt ggttgaaaaa tctggcaaat cgaagctgat tttcttgcct
    26461 actgactgac cttgaccagc aatctcgaca ccttccatat ccataactgg ttcgtagaat
    26521 ttcttgattt gacttggggt ttgaacacta ggaagttcaa tagctgcgcg gtgaagagta
    26581 ttataaactt ccacctcctt cagcatttcc agagcttctt tgatggtatc tgactgacga
    26641 ttgtctgctt gggagctatc ttggagagga ctcttggttt ccaactctcc gatagcttct
    26701 ctggtcaact gatcttcgtc aataaaacga taactaaagt tgagcttgtc cttagtaaac
    26761 actttactga tagcccaaag ccaatcttgg aaattccgtg cttgcagtct agtattgcta
    26821 tttagtttcc catttttggc tgctgggtat tccttggatt ccagcttttc acgagaaccc
    26881 ttgccgacaa gatagagctt tttctcagcc cgcgtcatag caacatacag caaacgcatc
    26941 tgctcagaat agcttgctag ctgtaattcc tcttcgttct gcctataggt cagactagga
    27001 atggagagtt tgatggtttt aggatagtgg tcttctactg cccctgtctc catcttggca
    27061 atatatttga caccaagacc attctgacga ctgagaatga cttctgacat agagtcttgc
    27121 ttgttgaaat cttgatccat attgaggata aagacgtaag gaaactccag ccctttactc
    27181 ttgtggatgg tcatgagctc tactgcatct tttggcggtg cgacggccac gcttgccaaa
    27241 tcgtgctggg cttctaagac ttggtcaatc atacgaataa aacgcgacaa acctttgaaa
    27301 ttgctctttt caaattgatc agcacgcagt gctagggcat agagattggc ctgcctagca
    27361 ggaccattcg gcaaagcccc aacatagtca taataaaaac ggtcgttgta aatcttccaa
    27421 atcaagtcat agagagagtg ggttttggca tacaagcgcc aagaagctag gatatccatg
    27481 aattgcttta gtttttcaac tagagctgtg tgaatcaagc ctttttgact acttgccatt
    27541 ttttgtgcat tgaccagttt ctcatagaga ttttcgtgga ctttatcctc tgctttctga
    27601 agggacaaac gtgctagctc atcctcatca aaaccaaaca ttggagactt cataagggca
    27661 accaaggcgt agtcttgcag gggattgtga atgacacgaa gagtgtctag catgacttgc
    27721 acttctaggg attggagata attgttttgc tctccgtcag ttttgacagg aatcccgtac
    27781 tcagacaggg cgaggagaat ctggtcatta cgactgcggc tggaggtcag aagggcaatt
    27841 tccttaaagg caacaccttt ttcttgatga agtttcagaa tctccttgat aactaagcgc
    27901 atttcgcctg ttagtttcgt ttctgtttga ctctcttctt cctcacctgt atcgtccttg
    27961 tcgtagagga gaaattctgc cttgttgtct ggattgggag tcagtttggt attggcaaaa
    28021 acaagctggt gcttgttatc atagttgatt tcaccgacct cttggtccat gagacgttca
    28081 aagacatcat tggttgctga cagcacttct gaactactac ggaaattttc cttgaggaga
    28141 atgagcttgc cttcttgggg attttgcgca tagcgttgga atttctcatt gaaaatctgc
    28201 gggtctgcct gacggaaacg atagatggat tgcttgatat ctcccaccat aaagcgattg
    28261 tggccattag acaacaattc cagcatccgt tcttgaatat ggttggtatc ctgatactca
    28321 tcgaccatga cttcatggaa gcgctcctga taagactcac gaacttgtgg gaaattctct
    28381 aaaatctcaa tggtgtaatg gctgatatca gcgaattcaa aggcattttc ctggcgtttg
    28441 cgctgacgat aagcctccac aaaatgactc ataaaggttt ggaaggtttt agctagtttc
    28501 catgtgtctt gatgataacg ttcttgatag tcgagaatgg ttatctggtc tgataattgt
    28561 cctagtttag caaactgggt ctttctctct tcgttgtagg catcagccag gggcttcaaa
    28621 tcagccttac gactggcatt agtcagagct cgaccgtttt tctccttaga gatggcgaca
    28681 acacgcgcaa gcactgcctg ataagcctga ctatcggact cctgatttag ggagcaaatt
    28741 tcatccagaa ttaactgaac attttctaaa taggcagcct ttgcaaactc cttggcatcg
    28801 ttatccagat ggtaacggaa aaagctttcc aaatcccaaa gggcttgttt gatttgctca
    28861 gtcagttttt ctttttcact ggtaaaatca gctttctcaa atcctttgag gaaagattca
    28921 ctcagccact tttgaggatt actggtggat tggaggaagt catagatttt atagacctgc
    28981 tggcgcagac cccgttcgtc cttgccacgc ccagcaaagt ttttcagcaa atgactaaag
    29041 gtctctttct gtttaccttg gtaatgcgct tcaaagacct catgaaagac ttcgttttcg
    29101 agaagaagtt gctcgctttg gttttgtaaa atacggaaat taggtgcaat atcaagcaga
    29161 taaccatgtt tgccaaggaa tttttgtgtg aaagagtcca tggttccgat ggcagcgttt
    29221 ggtaggtctg ccaactggcg tcccaagtgt tgtttgaggt cgacatcatc tgtttcttgg
    29281 attttcttgc tgattttttt ctctaaacgt tctttaagtt cagttgcagc cttgacggta
    29341 aaggttgaga taaagagttg agaaatttcg acaccacgcg ccaattggtc cagaatgcgc
    29401 tctgccatga caaaggtctt tccagaacca gccgatgctg agaccaggat attctgacca
    29461 gaagtgtaga tagcttcgat ttgctcggca gttttctttt gttccttgct cgaatttgct
    29521 tctgcttctt gcagtttttg aatctcctcc tcacttaaaa agggaataag cttcatcgat
    29581 tcaactcctc tcttattttt tcaagccaag cttgcttgag tttttctccg accagacgct
    29641 tgccatcagc taggtccaac ttttctagga aacgggcttg gcccagatgg taattggctt
    29701 caaagcctgt aatagcctga tgttgctgga cgtatggggc aatgcttctg ccattttcag
    29761 tataaggatt gatggcgaac cggcctgcta aaatcttctc agcagctttc ttgtaaagat
    29821 aggcattgta gtccagtagg agctgaaatt cctcatctgt cagttgattc gccttgtttt
    29881 tgttataaaa ttcgcctaaa taactgcttt ctttttccaa gaagagccct tggtatttca
    29941 tagatttgct ggcttctacc actgctcctg ccagactttt taccgccatc agagattgga
    30001 caggttcagc catttccaag tacatggcgc cgaaaaagtt ctgctcccct tctcttttta
    30061 gggcagcaag ataggttggt aactgagaat tgagcccatt aaagaaatga ggaaactgga
    30121 actgagtcag actggatttg tagtctacta ctcctatcgc tccattagct ttcaaacggt
    30181 caatccggtc caccttgcct cgtacaaaga cactgcgtcc attgtctaat tgaataaagg
    30241 cttggtcttt tccaccaaaa tttgcttctt ctttgattgt ttcgatggct ggattgtgtc
    30301 ggagaatatg tccagttgtc cgtgcaacat caagcaaaac ttccttggta aactgggctt
    30361 ccaaactttc ttgataaata gcttcaaatt cgcgttcttg actggtttct tgaatagctt
    30421 gttctagacg ttggtcaaag gaatcttcat taggcaactg caaggcgcgt tcaaagatac
    30481 gatgcaagaa attcccgtga ctacgggcat caggacgcaa acgtaattcc tcctgcaagc
    30541 ctaaaacgta gcgtaggaaa taactgtatt cattgcgata aaactctgtc aaacccgacg
    30601 tagacaggta aaactcctgt ttggcaggat agagagcttg caaggtgtcc ttggctaagg
    30661 tcttgctgct tggactgatt gggatggctg gattttccag accttgctga tctagttttt
    30721 tacctatgac acgcgacaga accttgacaa aagtcaaatc ttgctcagta tcgctcatct
    30781 caccctgctg gtgataggca accagactag acaaaagact gtgataggac cccatatcct
    30841 ccttagacag tcctttgtga ttcatcctct tctctctccg cctaaatcca aaatggatca
    30901 actcttgaag ataggcagat tccttacttt cactttcgtt aaaaaggctt ggagccgaca
    30961 agaacaactg cttacgagca gaattgacca aggaaagcat agtgtagcga tttttcttga
    31021 gattttcact gctggcaatc agtaattgaa cgccttcttc ggtcgtttgg tttaggtttt
    31081 gcctttcttc atctgtcaga agactggtgt tttgagaaat ttttggtaaa ttgtcctgag
    31141 ttagtccaat agcatagaca aagtcagcag tcaatggtgc aatcaaatcg taactctgca
    31201 ccagaacagt gtccactgtt gctggaatgg tacggtattg ggacaaactc attccagaat
    31261 ggagcaaggc taggaagtct tccagactaa cctgtgaacc agcaaaaaca gtcgcaaatt
    31321 gttctaaaac atggcagaaa gccttccaaa cttcggcttg tctttcctgt tctacagctt
    31381 ccaaagtggt tgtcaaatct tgtaactgct tggtcacagc tccttctttt agaaagacac
    31441 tccatttttg taggaggttt tcagcctttt gttttcggct ggcaaagagg gtttcaagag
    31501 gtgctaaaat tctcaggcgg aggacattca aacgctcaag attaaatttt ccatggtggg
    31561 atttggtgaa agtttgctga aaggctggca agccattgat accaagatag cggatatatt
    31621 gctcaaaagc atcaatatca gactgactga ggtcagtata caaatcagtt ctaagaagat
    31681 taatcaaatc ctcctgacga aaacggtaac gttttaaagc taaaatagac tcgacaaact
    31741 gagtcaaggg atgatgagcc atggcttcgc ttctaccaag ataaaaagga atctgatact
    31801 ggtcaaaaat ggttttgaga gataactggt aagaagctac atcccccaag agaatacgaa
    31861 aatgcttgta gctcaggtct gagttctcat gtaatttctg acgaatgcta cgggctacta
    31921 gctccaactc ctccttttgc gtcaaacaag accagatttg taaattttca cggtctttct
    31981 catcgacatc caaagcgagt tctgaaaagt cataagaaga ctccaacaaa cgagaggcct
    32041 tgtcaaaact atccatcttc tcatgagttt gagaacagtc ctgagcaggc gtttggtatt
    32101 tagaagccag atgatggaga aattttacgc tggcttggta gagattgccc tcgctaaaag
    32161 gactggtata ggctttctta ctagcataag ccccgataac aatctcaaca cctttgccgt
    32221 gaagtaagtc cacaacccgc tcttcctcag cagaaaaacg agtaaagccg tcaatgacca
    32281 aggtgatttg attaaaatca ctacttacct tgtcattctc aatagcctca atcaaatggg
    32341 acaactgact tccctgggct aactgacctt gattaagata ggctgttact ttctcaaaaa
    32401 tcaagagtaa atccgccctc ttatcctcat ctgttaaatt ctccaagtcc aaaaaactca
    32461 tctgagattt ggtcatctca tggtaaagct caattaactg ctggatcaat tgaggatcct
    32521 gcttaatagc gccataaaca cgcaagtcct tgggatcgag ttcggcaagg catttgtaaa
    32581 aggccaaccc aagaccgata tcatcaagag tagttttaac tggtaaatca ttcaagacca
    32641 gataacgagc catttgagca aagcgcgtga cggtaatcga aaaagaagcc tgctgggaca
    32701 agcattccag cacggcgcgt tccttttcaa aagaaagaga gttgggggca atgtagaaga
    32761 cccgcttgcc agctgcaact agctcttctg cctctcttgt tagaatttct gtcaaagaag
    32821 ttcgaatatc agtataaagt aatttcatct cagcctcgtt ggaatttttc atcaccctat
    32881 attataccat gattagcctc gtaaatctgt taaaatattt aggccatcct ttcttttctt
    32941 catcatctgc taaatcttaa atacttagct ttacttgtat tagatagaat aagtctggct
    33001 actgaaaatc acataataaa aaagcctcgg taacaaggct ttgagtttta tgattgtttc
    33061 ttaggtacgg aatacacttc aatgtgttgt cccagtatct taatgtcgac tggtagattg
    33121 tctgatttat cgccatcaac atcggactct aattcgatat cagaagaagt tttaatatta
    33181 cgtgccttta tatattcaat attcttgata gaatgattga actatagtaa attgaaacta
    33241 taatagtaca ccgtggatgc taaaatattt ctagaaatta atttgatttc cctaatcaag
    33301 ctgttcgtat cttatttcaa tcta
//
LOCUS       DAVAZT010000021        31130 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVAZT010000021 DAVAZT010000000
VERSION     DAVAZT010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31130
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.021"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(1..349)
                     /locus_tag="VQT45_000910"
                     /pseudo
     CDS             complement(1..349)
                     /locus_tag="VQT45_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            344..598
                     /locus_tag="VQT45_000911"
     CDS             344..598
                     /locus_tag="VQT45_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET2359255.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIGAEAIRRNCERGAIFSGKIKHHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            942..2276
                     /gene="trmFO"
                     /locus_tag="VQT45_000912"
     CDS             942..2276
                     /gene="trmFO"
                     /locus_tag="VQT45_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HET2359256.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNDGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRIFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEAIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            2360..3097
                     /locus_tag="VQT45_000913"
     CDS             2360..3097
                     /locus_tag="VQT45_000913"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HET2359257.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            3106..3663
                     /gene="frr"
                     /locus_tag="VQT45_000914"
     CDS             3106..3663
                     /gene="frr"
                     /locus_tag="VQT45_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HET2359258.1"
                     /translation="MANAIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRIHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVV
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            3723..4577
                     /gene="cvfB"
                     /locus_tag="VQT45_000915"
     CDS             3723..4577
                     /gene="cvfB"
                     /locus_tag="VQT45_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HET2359259.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTSLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            4586..4801
                     /locus_tag="VQT45_000916"
     CDS             4586..4801
                     /locus_tag="VQT45_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HET2359260.1"
                     /translation="MRKSFYTWLMTERNPKSNNPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            4887..5855
                     /locus_tag="VQT45_000917"
     CDS             4887..5855
                     /locus_tag="VQT45_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HET2359261.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMALVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            6035..6535
                     /locus_tag="VQT45_000918"
     CDS             6035..6535
                     /locus_tag="VQT45_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2359262.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            6538..6798
                     /locus_tag="VQT45_000919"
                     /pseudo
     CDS             6538..6798
                     /locus_tag="VQT45_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(7165..8276)
                     /gene="ald"
                     /locus_tag="VQT45_000920"
                     /pseudo
     CDS             complement(7165..8276)
                     /gene="ald"
                     /locus_tag="VQT45_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253293.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            8453..9022
                     /locus_tag="VQT45_000921"
     CDS             8453..9022
                     /locus_tag="VQT45_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2359263.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            9090..9740
                     /locus_tag="VQT45_000922"
     CDS             9090..9740
                     /locus_tag="VQT45_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HET2359264.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTSVKETNLQ
                     AEVAAVSKDSSTGKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD"
     gene            9724..11964
                     /locus_tag="VQT45_000923"
     CDS             9724..11964
                     /locus_tag="VQT45_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HET2359265.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQNLVDSVERVRILPDTIKVNGDSL
                     SFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
                     LKTQGIYQTLNIKRIQSLQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     VFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVASRPLVFGQPNEWLLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIKKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            12144..12332
                     /locus_tag="VQT45_000924"
     CDS             12144..12332
                     /locus_tag="VQT45_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359266.1"
                     /translation="MTVTKSYKYDWNTVLEYSTNYHDHQYAWIPEWSRYYSYSEYKVG
                     GGWNYARYEVINYYTGGY"
     gene            12364..12951
                     /locus_tag="VQT45_000925"
     CDS             12364..12951
                     /locus_tag="VQT45_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2359267.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            12955..14130
                     /locus_tag="VQT45_000926"
     CDS             12955..14130
                     /locus_tag="VQT45_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359268.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILALFVSVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWKDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLPKQIDNVDLNWSMGMVLLPCLIIFLLLGILFIERWGSSQKKRIF"
     misc_feature    14304..14435
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            14451..14981
                     /gene="infC"
                     /locus_tag="VQT45_000927"
     CDS             14451..14981
                     /gene="infC"
                     /locus_tag="VQT45_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HET2359269.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            15014..15214
                     /gene="rpmI"
                     /locus_tag="VQT45_000928"
     CDS             15014..15214
                     /gene="rpmI"
                     /locus_tag="VQT45_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HET2359270.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            15266..15625
                     /gene="rplT"
                     /locus_tag="VQT45_000929"
     CDS             15266..15625
                     /gene="rplT"
                     /locus_tag="VQT45_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HET2359271.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            15683..16063
                     /locus_tag="VQT45_000930"
     CDS             15683..16063
                     /locus_tag="VQT45_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2359272.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            16313..17113
                     /locus_tag="VQT45_000931"
     CDS             16313..17113
                     /locus_tag="VQT45_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HET2359273.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVNQRVCEDGPVFRTGTVVL"
     gene            17076..18062
                     /locus_tag="VQT45_000932"
     CDS             17076..18062
                     /locus_tag="VQT45_000932"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HET2359274.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            18104..20005
                     /locus_tag="VQT45_000933"
     CDS             18104..20005
                     /locus_tag="VQT45_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HET2359275.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYM
                     AKNETVDGYQLGSDGKWLGGKATNENAAYYQVVPVTANVYDSDGEKLSYISQGSVVWL
                     DKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIP
                     VASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINN
                     SLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYL
                     SAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMK
                     INEKLGGKD"
     gene            complement(20066..21721)
                     /gene="pavA"
                     /locus_tag="VQT45_000934"
     CDS             complement(20066..21721)
                     /gene="pavA"
                     /locus_tag="VQT45_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HET2359276.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPLANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            21826..22323
                     /gene="ybeY"
                     /locus_tag="VQT45_000935"
     CDS             21826..22323
                     /gene="ybeY"
                     /locus_tag="VQT45_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HET2359277.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLGYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            22304..22699
                     /locus_tag="VQT45_000936"
     CDS             22304..22699
                     /locus_tag="VQT45_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HET2359278.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            22716..23615
                     /gene="era"
                     /locus_tag="VQT45_000937"
     CDS             22716..23615
                     /gene="era"
                     /locus_tag="VQT45_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HET2359279.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPDRFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            23664..24488
                     /gene="mutM"
                     /locus_tag="VQT45_000938"
     CDS             23664..24488
                     /gene="mutM"
                     /locus_tag="VQT45_000938"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HET2359280.1"
                     /translation="MPELPEVETVCRCLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARSSQTLTAEEATAIHDQTIAVLSQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQGCVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            24488..25093
                     /locus_tag="VQT45_000939"
     CDS             24488..25093
                     /locus_tag="VQT45_000939"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HET2359281.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFWQEIILENGELNRPLLASLIFSNPDEREWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            25080..26279
                     /locus_tag="VQT45_000940"
     CDS             25080..26279
                     /locus_tag="VQT45_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HET2359282.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            26279..26428
                     /gene="rpmG"
                     /locus_tag="VQT45_000941"
     CDS             26279..26428
                     /gene="rpmG"
                     /locus_tag="VQT45_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET2359283.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            26468..26701
                     /gene="secG"
                     /locus_tag="VQT45_000942"
     CDS             26468..26701
                     /gene="secG"
                     /locus_tag="VQT45_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HET2359284.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            26803..29157
                     /gene="rnr"
                     /locus_tag="VQT45_000943"
     CDS             26803..29157
                     /gene="rnr"
                     /locus_tag="VQT45_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HET2359285.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVSSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSHSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            29120..29587
                     /gene="smpB"
                     /locus_tag="VQT45_000944"
     CDS             29120..29587
                     /gene="smpB"
                     /locus_tag="VQT45_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HET2359286.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            29603..30463
                     /gene="tehB"
                     /locus_tag="VQT45_000945"
     CDS             29603..30463
                     /gene="tehB"
                     /locus_tag="VQT45_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HET2359287.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEDVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            30536..>31130
                     /gene="coiA"
                     /locus_tag="VQT45_000946"
     CDS             30536..>31130
                     /gene="coiA"
                     /locus_tag="VQT45_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HET2359288.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQG"
BASE COUNT         9240 a         5772 c         7124 g         8994 t
ORIGIN      
        1 cgtcgcatca atcattaccg tgtcctcaga actgagagga gttcttgaaa tcgtaacacc
       61 acctttgaac aagagttact tcaacccatt ggctccgacg gagtaagttg ctttcgtgga
      121 taccaaaatc agccgcaatt tcttcataag tgcgatattc tcgcacatat tgaagagtgg
      181 ccataagaag gtcttctagg cttaatttag gttttcgtcc accttttgcg tgtttaagtt
      241 gataagctgt ttttaataca gctaatatct cttcaaaagt cgtgcgctga acaccaacaa
      301 gacgcttaaa tcgtgcatca gttagttgtt tacttgcttc ataattcata gaactactat
      361 accatatttt gtttcgcagg aagtctattg gaaagtaaga aatattggag ctgaggcgat
      421 tagaagaaat tgtgagcgtg gtgctatttt ttcaggtaaa ataaaacatc acgaagattc
      481 tcagtttaaa ggagaccact atgttgaatg ttatgctgtt ttagataata cggttatagc
      541 aagagataga ataacagtcc ctatcgatcc gttatgtgga aaagatttta tagagtagca
      601 tataattgat tcttaactgg aatactctct atctctttac atcaagaaaa tgactaaaca
      661 gggaagtttg ccttcttccc tttttttgtt atactagtag aagaaaaaaa tagaaagatt
      721 tgtgggagtg aaaaagtccg ggggactttt tcagcttgag ccaagaaatt cgagagcgag
      781 gaaagtccgg gggacttttt cagcctgagc caagaaattc gagagcgaag taagtccaat
      841 ggactttttc agcctgagcc aagaaactcg aaagctcgta agtctgattg gctttttcaa
      901 tgtgaatctt aacttcacac tcccaaagag gtattagtgt cgtgtctcaa tcttatatca
      961 atgttatcgg tgctggtttg gcaggttctg aagcagctta ccaaatcgca gagcgtggta
     1021 ttccagttaa actatatgaa atgcgtggtg tcaagtcgac tccccagcat aaaacagaca
     1081 attttgctga gttggtttgt tccaattctt tgcgtgggga tgctttgaca aatgcagttg
     1141 gtcttctcaa ggaagaaatg cgtcgcttgg gttctgttat cttggaatct gctgaggcta
     1201 cacgtgttcc tgcaggtggt gcccttgcag tggaccgtga tggtttctct caaatggtga
     1261 ccgaaaaagt tgccaaccac cccttgattg aagtggttcg tgatgaaatt acagaattgc
     1321 cgacagatgt tattacggtt atcgctactg gtcctttgac aagtgatgcc ttggctgaaa
     1381 agattcatgc ccttaatgac ggtgatggtt tttatttcta cgatgcggca gcgcctatta
     1441 tcgatgtcaa cactatcgat atgagcaagg tctacctcaa atcacgttat gataagggag
     1501 aagcggccta cctcaatgcc cctatgacca agcaagaatt tatggatttc catgaagctt
     1561 tggtcaatgc agaagaagca ccgcttaatt cttttgaaaa agaaaagtac tttgaaggct
     1621 gtatgcctat cgaagtcatg gccaaacgtg gcattaaaac tatgctttat ggccctatga
     1681 agccagtcgg tcttgagtac ccagacgact atacaggacc tcgtgatgga gaatttaaaa
     1741 caccttatgc ggttgtgcaa cttcgtcagg acaatgcagc tggtagcctc tacaatattg
     1801 ttggtttcca gacccacctc aaatggggag aacaaaagcg tatcttccaa atgattccgg
     1861 gtcttgaaaa tgcagagttt gtccgttatg gtgtcatgca tcgcaattct tacatggatt
     1921 caccaaatct tcttgagcag acttaccgtt ctaagaaaca accaaatctc ttctttgctg
     1981 gtcagatgac gggggtggaa ggctatgttg agtcggcggc ttcaggctta gttgcgggaa
     2041 ttaacgcagc tcgtctcttc aaggaagaaa gcgaggctat tttccccgag acgacagcga
     2101 ttggaagctt agctcattac attacccatg ccgacagcaa acatttccaa ccaatgaatg
     2161 tcaattttgg gatcatcaag gagttggaag gcgagcgtat ccgtgataag aaggctcgtt
     2221 atgaaaaaat tgcagagcgt gcccttgccg acttagagga atttttgact gtctaatttt
     2281 tttgaaagaa ttgctcatga tactataaaa atcttagaaa ttgtgataaa ataggtagga
     2341 tgaaagaagg agagtgaaaa tggcgaatcc caagtataaa cgtattttaa tcaagttatc
     2401 aggtgaagcc cttgccggtg aacgtggcgt agggattgat atccaaacag ttcaaacaat
     2461 cgcaaaagag attcaagaag ttcatagctt aggtatcgaa attgcccttg ttattggtgg
     2521 aggaaatctc tggcgtggag aacctgcagc agaagcaggt atggaccgtg ttcaggcaga
     2581 ttacactgga atgcttggga ctgttatgaa tgctcttgtg atggcagatt cattgcaaca
     2641 agttggggtt gatacgcgtg tacaaacagc tattgctatg caacaagtgg cagagcctta
     2701 tgtccgtgga cgtgcccttc gtcaccttga aaaaggccgt atcgttatct ttggtgctgg
     2761 aattggttca ccatacttct cgacagatac aacagcggcc cttcgtgcag ctgaaatcga
     2821 agcggatgcc atcctcatgg ctaaaaatgg tgtcgatggt gtttacaatg ccgatcctaa
     2881 gaaagataag acagctgtta agtttgaaga attgacccac cgtgacgtta tcaataaagg
     2941 tcttcgtatc atggactcaa cagcttcaac cctctcaatg gacaacgaca ttgacttggt
     3001 tgtcttcaac atgaaccaat caggcaacat caaacgtgtc gtatttggtg aaaatatcgg
     3061 aacaacagtt tcaaataata tcgaagaaaa ggaataagaa agaatatggc taacgcaatt
     3121 attgaaaaag ctaaagagag aatgacccag tctcaccaat cacttgctcg tgaatttggt
     3181 ggtatccgtg ctggtcgtgc caatgcaagc ttgcttgacc gtatacatgt agaatactat
     3241 ggagttgaaa ctcctcttaa ccaaatcgct tcaattacga ttccagaagc gcgtgttttg
     3301 ttggtaacac catttgacaa gtcttcattg aaagacatcg aacgtgcctt gaacgcttct
     3361 gatcttggta tcacaccagc taatgacggt tctgtgattc gcttggttgt cccagctctt
     3421 acagaagaga ctcgtcgtga ccttgctaaa gaagtgaaga aggtcggcga aaatgctaaa
     3481 gtggctgtcc gcaatatccg tcgcgatgct atggacgaag ctaagaaaca agaaaaagca
     3541 aaagaaatca ctgaagacga attgaagact cttgaaaaag acattcaaaa agtaacagac
     3601 gatgctgtta aacacatcga cgatatgact gccaacaaag agaaagaact tttggaagtc
     3661 taaaaataaa cagaaaaact cagttggcat tgctggctga gttttattcg aaagaaggaa
     3721 atatgaatac aaatcttgca agttttatcg ttggactgat catcgatgaa aacgaccgtt
     3781 tttactttgt gcaaaaggat ggtcaaacct atgctcttgc taaggaagaa ggccaacata
     3841 cagtagggga tacggtcaaa ggttttgcat acacggatat gaagcaaaaa ctccgcctga
     3901 caagcttaga agtgactgcc actcaggacc aatttggttg gggacgtgtc acagaggttc
     3961 gtaaggactt gggtgtcttt gtggatacag gccttcctga caaggaaatc gttgtgtcac
     4021 tcgatattct ccctgagctc aaggaactct ggcctaagaa gggcgaccaa ctctacatcc
     4081 gtcttgaagt ggataagaaa gaccgtatct ggggtctctt ggcttatcaa gaagacttcc
     4141 aacgtcttgc tcgtcctgcc tacaacaaca tgcagaacca aaactggcca gccattgttt
     4201 accgtctcaa gctatcagga acttttgttt acctaccaga aaataatatg cttggtttta
     4261 ttcatcctag cgagcgttac gcagagccac gtttggggca agtattagat gcgcgcgtta
     4321 ttggtttccg tgaagtggac cgcactttga acctctccct caaaccacgc tcctttgaaa
     4381 tgttggaaaa cgatgctcag atgattttga cttatttgga aagcaatggc ggtttcatga
     4441 ccttaaatga caagtcatct ccagacgaca tcaaggcaac ctttggcatt tctaaaggtc
     4501 agttcaagaa agctttaggt ggtcttatga aggctggtaa aatcaagcag gaccagtttg
     4561 gtacagagtt gatttaggga ggcttatgag aaaatcattt tacacttggc tcatgaccga
     4621 gcgcaatcct aaaagtaaca atcccaaagc aattttggca gacctcgctt ttgaagaggc
     4681 agcttttcca aaacatacag atgattttga tgaggtcagt cgctttttgg aggagcatgc
     4741 cagtttctct tttaacctag gagattttga cagcatttgg caggaatatc tagaacacta
     4801 gcatttattc attgggtttg ggctagtaat ttctccatcc ctctgctata ataaaaagaa
     4861 ataaaaggat tagagaggtt ctttatttga aggaacattc aatagacatt caactgagtc
     4921 atccagatga cctgtttcat ctttttggtt ccaatgaacg ccatcttcgt ttgatggaag
     4981 aagagcttga tgttgtgatt catgctcgta cggagattgt ccaggttttg ggagaagagt
     5041 ctgcttgcga ggaagcccgt caggttattc aagctctcat ggccttggta aatcgtggga
     5101 tgaccgttgg tacgccagat gtagtgacgg ctattagtat ggtcaaaaat gatgaaattg
     5161 acaagtttgt cgccctttac gaagaagaaa tcatcaagga taatactggg aagcctatcc
     5221 gcgtcaaaac cttaggtcaa aaactttatg tggacagtgt caaacagcat gatgtgacct
     5281 ttggaattgg gccagcaggt acagggaaga ccttccttgc agtgaccttg gcagtgactg
     5341 cccttaaacg tgggcaagtc aagcgaatta tcctaactcg tccagcggtg gaagcgggag
     5401 agagtcttgg atttcttccg ggtgatctta aggagaaggt ggatccttac cttcgtcctg
     5461 tttacgatgc cttgtatcaa attcttggga aagaccaaac gactcgtctc atggagcgtg
     5521 aaattatcga aattgcgccc cttgcctata tgcgtggccg gaccttggat gatgcctttg
     5581 tcattctcga tgaggcgcaa aacacgacca tcatgcagat gaagatgttc ttgacgcgtt
     5641 taggctttca ttctaagatg attgtcaatg gagatatcag tcagattgac ctgccacgta
     5701 atgtcaagtc cggtttgatt gatgctcaag agaaactcaa gaacatccat cagattgact
     5761 ttgttcattt ttcagccaag gatgtggttc gccatccagt tgtcgctcag attatccgag
     5821 cctatgaata ttctactgaa gttgcacacg actgattttg aggaagttcg cctgcaaaag
     5881 aatatacttt tgagagagga aaatccagtt gtataggcta aaggtttgag acaacgatta
     5941 ggcacgatgg aaagaacttt tatgtggctg atgacgatca gtgcatcttc ctgtgtcata
     6001 atcacagggc acaagaaagt aggaatttga aaagatgatt gaccaactat ctaagtatta
     6061 cagttgtagg atactaactg aaaaggatat tccaagtatt ttatctttat atgaaagtaa
     6121 tcctctgtat tttcagcatt gtccaccaga gccaaatttt gcaactgtaa aagaggacat
     6181 gctttgtcta cctgaaggta aagctaaggc tgataagttt tttgttggat tttggaatgg
     6241 ctctgacctt gtggctgtta tggattttgt ctatgcatat cctgatgagg agactgtttt
     6301 tattggtttg tttatggttg atcaagccta tcagaggaaa gggattggta gtcatattgt
     6361 gacagaagca ctagcttatt ttgctaagaa ctttcgaaag gcacgtttgg cttatgttaa
     6421 gggaaatccg caatctcagc atttttggga aaagcagggc tttaaatcaa ttggatgcga
     6481 ggttaagcaa gaactctata cggttgttat cgctgaacag agcctagaag attagaaatg
     6541 gcatcaagta agaactattt ggaatttgtt ttggaacaat tatcaggatt agatgatgtg
     6601 acttaccgtt ccatgattgg ggagtatatt ctttacttcc gcggcaagat tattggcggc
     6661 atttatgacg atcgcttttt agttaaaccc gtgcaagcag tcttagataa gattgaccaa
     6721 tcttcttttg agtttccata caaaggtgcc aaagaaatga tttgagtgga agaacttgat
     6781 aataagatgt ttctataaga cctgatttta gctatgtata accaactgcc aacgcccaaa
     6841 cctaaaaaga aaaagcaagg gtgaacgaag taaaaaagaa gtctgctaag gccctgtctt
     6901 tgcacgggta aaattttata tataaaaaga agctgggact aaagagctca gcttcctttg
     6961 gtttatataa ttgtcattac aagacgaagt ggttgggcga aactctgttg actttattca
     7021 atttagagtt tcttatgcac aattgagtct ggaacgaaag tctccagttg caaagtatac
     7081 agtacaataa accaacgatg taatagctga tgacacaaag cacagtgggt aggacttgcg
     7141 aagtcaccct tttcttttca aaatttatac taaatcattg atatcagtgt agtcacgatt
     7201 aagtccttga gcaactggta ggctagtcaa gtaaccttga taagtggtca caccttgacg
     7261 caagccttca tcttcagaga ttgcttgtgc gaatcctttg ccagccaaag cttcgatata
     7321 aggaagagtg acattggtta gggcgatggt tgaagtgcgg gcaaccgcac cagggatatt
     7381 ggcaacggca tagtggagaa caccgtgttt ttcatagacg ggttcatcgt gcgttgtcac
     7441 acggtcagct gtttcgataa cgccaccttg gtcaacagca acgtcaacga tacagagcct
     7501 ggacgcattt gtttgaccat ctcatctgtc accaattccg gtgcttttgc accagggatg
     7561 agaatggctc caatcaccac atcagcatct ctcacacttg cttcaatgtt gaatgaatta
     7621 gatataatag tttgaatttg acttccaaag acttcttcta gaactgagag acgcttggca
     7681 ctaatatcta aaatagtcac ttgagcacca agaccaaggg cgatgcgggc agcatgtgta
     7741 ccgacgacac catcaccgat gatagttact tttccttttg gaacacctgg tacaccacca
     7801 agtagaacac cagagccacc agcttgctta gtaaggaagt gagctccgat ttgaacagcc
     7861 atacgacctg caacctcact cataggaacg aggagcggta gttgtccttg attgtcacga
     7921 acagtttcat aggcaattcc tgttgttttt gctgctaaca tagcatctgc taattctgga
     7981 gcagcggcca tgtgcaagta ggtgaagaga agaagatcgt cgcgcaagta accgtattca
     8041 gaacttaaag gttcttttac tttcacaacc aactctgctg cccaagcttc accagcagta
     8101 gcgacaatct cagctccttg cttttgatag tcagcatcag taaagccaga accgagacca
     8161 gcatttgttt cgataaggac acgatgacca cgactaacta agctatgaac acctgcaggt
     8221 gtgagggcga cacggttttc gttattttta atttcttttg ggattccgat taacattgag
     8281 ataacctacc tttcaattga cggtcttgtt ttggttgtca cattccagtt cataaatcaa
     8341 aaatgtgacg gtttcattgt atatgaaacc gcttcaaaaa tcaagaaaaa cttgtcatcc
     8401 aaattttttt atgctagact agtgaaaatc aagctctaat ggagggaaaa gtatggaatc
     8461 aatatttgtg aaatttgccc agtatccgtc tatagaaacg gagcgtttat tgcttagacc
     8521 tgtaactttg gatgatgcgg aagcaatgtt tgactatgcc tcggacaagg gtaatacacg
     8581 ttacactttt ccaaccaatc aaagcttgga agaaaccaag aataacattg ctcagttcta
     8641 cttggctaat cccttgggac gttgggggat tgaattaaaa gataacggca agtttatcgg
     8701 aactattgac ttacacaaga ttgatcctgt tcttaagaag gcagctattg gctacattat
     8761 caataaaaag tattggaatc aaggattaac gacagaagcc aatcgtgctg tgattgagct
     8821 agcttttgag aagataggga tgaataagtt gactgccctt cacgataagg ctaatcccgc
     8881 gtcaggaaag gtcatggaga aatcaggcat gcgtttttcc catgcagaac catatgcttg
     8941 tatggaccag catgaaaaag gccgaatcgt gacaagagtt cattatgtct tgaccaagga
     9001 agactatttt gcaaataaat aagcagttga aaagaaattt ttcgactgtt ttttcttcct
     9061 cttacgaata atctaagaga ggagaaaata tggaagcaat tatcgagaaa atcaaagagt
     9121 ataaaatcat cgtcatctgt actggtctgg gcttgcttgt aggaggattt ttcctgctaa
     9181 agccagctcc acaaacatct gtcaaagaga cgaatttgca ggctgaagtt gcagctgttt
     9241 ccaaggactc atcgaccgga aaggaagtga acaaggaaga gaaggaagaa ccagttgaac
     9301 aagatctaat cacagtagat gtcaaaggtg ctgtcaaatc gccagggatt tatgacttgc
     9361 ctgtaggtag tcgagtcaat gatgctgttc agaaggctgg tggcttgaca gagcaagcag
     9421 acagcaagtc gctcaatcta gctcagaaag ttagtgatga ggctctggtt tacgttccta
     9481 ctaagggaga agaagcagtt agtcaacaga ctggttcggg gacagcttct tcaacaagca
     9541 aggaaaagaa ggtcaatctc aacaaggcca gtctggaaga actcaagcag gtcaagggac
     9601 tgggaggaaa acgagctcag gacattattg accatcgtga ggcaaatggc aagttcaagt
     9661 cagtagacga gctcaagaag gtctctggca ttggtgccaa gaccatagaa aaacttaaag
     9721 actatgttac agtggattaa gaatttctct attcccctaa tttacctgag ttttctatta
     9781 ctatggcttt actacgccat tttctcagta tcctattttg ctttgttggg ttttgttttt
     9841 ctgctagtct gcctctttat ccaatttcct tggaaatcag caggtaaagt tctagtgatt
     9901 tgtggagtct ttggcttctg gtttctgttt caaacttggc aacagagtca agtgagtcaa
     9961 aatttggtgg attctgttga aagggtacgg attttaccag acactattaa ggttaacggt
    10021 gacagtctgt cctttcgtgg taagtctgat ggtcgtgctt tccaagtcta ttataaactc
    10081 cagtccgagg aggagaaaga agcctttcaa gctttaactg accttcatga gataggacta
    10141 gaagggaagc tttcggagcc agaagggcag agaaattttg gtggctttga ctaccaaggc
    10201 tatctgaaga ctcagggaat ttaccagaca ctcaatatta aaagaatcca gtcactccaa
    10261 aaggttggca gttgggatat aggtgaaaac ctgtccagtt tacgtcgaaa ggctgtggtt
    10321 tggattaaga tgcacttccc agaccctatg cgcaattaca tgacaggact cttgctagga
    10381 catctggaca ccgattttga ggagatgaat gagctttatt ccagtttagg aattattcac
    10441 ctttttgcct tgtcaggtat gcaggtaggg tttttcatgg acggatttaa gaaactactt
    10501 ttacgattgg gcttgacaca agaaaagttg aagtggctga cttatccctt ttcccttatc
    10561 tatgcgggac taactggatt ttcagcatcg gttattcgca gtctcttgca aaagctactg
    10621 gctcaacatg gggttaaggg cttggataat tttgccttga cggtgcttgt cctctttatt
    10681 gtcatgccaa actttttctt gacagcagga ggagtcttgt cctgtgctta tgcttttatc
    10741 ctgaccatga ccagcaaaga aggggagggg ctcaaggctg ttactagtga aagtctagtc
    10801 atctccttgg gcatattgcc cattctatcc ttctattttg cggaatttca accttggtct
    10861 atccttttga cctttgtctt ttcctttctt tttgacttgg tcttcttacc gctcttgtct
    10921 atcttatttg tcctttcctt tctctatcca gtcattcagc tgaactttat ctttgaatgg
    10981 ttagagggca ttattcgctt ggtctcgcag gtggcaagta gaccgcttgt ctttggacaa
    11041 cccaatgaat ggcttttaat cctattgtta atttctttgg ctttggtcta tgatttgagg
    11101 aaaaacatta aaaagctaac ggtattgtgc ttattgatta cagggctctt tctcctgacc
    11161 aagcatccac tggaaaatga aatcaccatg ctggatgtgg ggcaaggaga aagtattttc
    11221 ctacgggatg taactgggaa aaccattctc atagatgtag gtggtaaggc agaatcttat
    11281 aagaaaatca aaaaatggca agaaaagatg acgaccagca atgcccagcg aagcttgata
    11341 ccctatctca aaagtcgagg agtagctaag attgaccagc taattttgac taacacggac
    11401 aaggagcatg ttggagattt gtcagagatg accaaggctt tccatgtagg ggagattcta
    11461 gtatcaaaag acagtctgaa acagaaggaa tttgtggcag aactacaggc gactcaaaca
    11521 aaggtgcgta gtatgatagt aggggagaac ttacccattt ttggaagtca gttagaagtt
    11581 ctatctccaa ggaaaatggg agatggagga cacgatgata ccctagttct gtatgggaaa
    11641 ttcttggata agcaatttct cttcacggga aatttggagg agaaaggaga gaaggacttg
    11701 ctgaagcact atccagactt gaaagtaaat gttttgaaag ctagccaaca tggcaataaa
    11761 aaatcatcaa gtccagcctt tctagaaaaa ctcaaaccag agcttactct tatctcagtt
    11821 ggaaagagca atcgaatgaa actcccccat caggaaacat tgacacgact ggaaggtatc
    11881 aatagcaaag tttatcgaac tgaccagcaa ggagctatac gttttaaggg gttggatagt
    11941 tggaaaatcg aaagtgttcg ataggaagga taaatgttgt agattagtga aataaactaa
    12001 aaatttgttg cataataatg ataaaaacgg cataatgaaa acgtattcaa tattgaggat
    12061 ataaaatcat taaaaatcag caaaagttgt tttagttagt tagtttataa tctattggtc
    12121 ttcttcagtc cagtgtatct gctgtgacag tcactaaaag ttacaagtat gattggaata
    12181 cggttttgga atatagtacc aactatcacg accatcagta tgcttggatt ccggaatggt
    12241 ctcgttatta cagctattct gagtataaag ttggcggagg ctggaactac gctcgttatg
    12301 aggtcataaa ctactatact ggaggttatt aatccttaaa gagtgagaaa aggagggctg
    12361 gatatgttaa atcttactca tgttacctta aaaacgcgac aagtcatctt gcaagatgcg
    12421 gattttacct ttaaaaaggg taggatttat ggccttcttg ctatcaatgg ctcgggaaag
    12481 acgacactat tccgagctat gagcaagttg cttcccctta gtagtggaca catcgcagtt
    12541 cctccttctt tgttttatta tgagagcgtt gaatggctgg atggaaactt aagtgggatg
    12601 gactaccttc gtctcataaa aaacatctgg aagtcagacc taaacttgag agatgaaatc
    12661 gcctactggg aaatggctga ctatatcagt cttcccatcc gcaagtattc cttagggatg
    12721 aagcaacgct tggtgattgc tatgtatttt ctcagtcagg ccaaatgctg gctcatggat
    12781 gagattacaa atggcttaga cgagtattat cgacagaagt tttttgatag gctagcacaa
    12841 atcgatagac aagaacagct ggttctttta agttcccact ataaggaaga gttggttgat
    12901 atctgcgata gagtagtaac cattcatcag gggcagatag aagaggttta gtttatgaaa
    12961 gatgttagtc tatttttatt gaaaaaagtt ttcaaaagtc gtttaaactg gattatctta
    13021 gctttatttg tatctgtact cggtgttacc ttttatttaa atagtcagac tgcaaactca
    13081 cacagcttgg agagcaggtt ggaaagtcgc attgcagcca acgagagggc tatcaatgaa
    13141 aatgaagaga aactctccca aatgtctgat accagctcgg aggaatacca gtttgctaaa
    13201 aataatttag acgtgcaaaa aaatcttttg acgcgaaaga cagaaattct aactttacta
    13261 aaagaagggc gctggaaaga agcctactat ctgcagtgga aagatgaaga gaagaattat
    13321 gaatttgtat caaatgaccc gactgctagc tctggcttaa aaatgggggt tgaccgcgaa
    13381 cggaagattt accaagccct gtatcccttg aacataaaag cacatacttt ggagtttccg
    13441 acccacggga ttgatcagat tgtctggatt ttagaggtta tcatcccaag cttgtttgtg
    13501 gttgcgatta tttttatgct aacacaacta tttgcagaaa gatatcaaaa tcatctggac
    13561 acagctcact tatatcctgt ttcaaaagtg acatttgcaa tatcctctct tggagttgga
    13621 gtgggatatg taactgtgct gtttatcgga atctgtggct tttcttttct agtgggaagt
    13681 ctgataagtg gttttggaca gttagattat ccctacccaa tttatagctt agtgaatcaa
    13741 gaagtaacta ttgggaaaat acaagatgta ttatttcctg gcttgctctt agctttctta
    13801 gcctttatcg tcattgtgga agttgtgtac ttgattgctt actttttcaa gcaaaaaatg
    13861 cctgtcctct ttctttcact cattgggatt gttggcttat tgtttggcat ccaaacaatt
    13921 cagcctcttc aaaggattgc acatctgatt ccctttactt acttgcgttc agtggagatt
    13981 ttatctggaa gattacctaa gcagattgat aatgtcgatc taaattggag catgggaatg
    14041 gtcttacttc cttgcctgat tatctttttg ctattgggaa ttctatttat tgaaagatgg
    14101 ggaagttcac agaaaaaaag aattttttaa tagattctag ctttcctata ggtagggaaa
    14161 ataagtaaaa actaacatag agagggaatc aacttgattc tctctttttg attcgaaaac
    14221 caaaccaaaa tacaaacaca aacttttcaa aaaataactt tttatcttga caagagctag
    14281 aaaacttggt atcatataaa agttgagaaa agcagaagtg agagcttctc gccttgtgac
    14341 attaagttgc ctggccctac ggatgaaaag tttcgaagaa acgctatcat aacgtgcggg
    14401 cttgtatatt tacgagtccg ctattgtttt tctctaataa aacaaaagag gtgaaaacca
    14461 tagcaaagca agacttattc atcaatgatg agattcgtgt acgtgaagtt cgcttgattg
    14521 gtcttgaagg agaacagcta ggcatcaagc cactcagtga agcgcaagct ttggctgata
    14581 acgctaatgt tgacctagta ttgattcaac cccaagccaa accgcctgtt gcaaaaatta
    14641 tggactacgg taagttcaaa tttgagtacc agaagaagca aaaagaacaa cgtaaaaaac
    14701 aaagcgttgt tactgtgaaa gaagttcgtc taagtccaac tattgacaag ggtgactttg
    14761 atacaaaact tcgtaatgca cgtaagttcc ttgaaaaagg aaataaagtt aaggtatcta
    14821 ttcgctttaa gggtcgtatg attacccata aagagattgg tgcaaaagtt ttagccgagt
    14881 ttgctgaagc aactcaagat attgccatca tcgaacaacg tgctaaaatg gatggacgtc
    14941 aaatgttcat gcaattggcg ccagcgactg acaaaaaata attgtcagaa agttaaataa
    15001 aggagaaaaa attatgccaa aacaaaaaac acaccgcgca tcagctaaac gtttcaaacg
    15061 tacaggttct ggtggactta aacgtttccg tgcttacact tctcaccgtt tccacggaaa
    15121 aactaagaaa caacgtcgtc atcttcgtaa agcatctatg gtgcattcag gagattacaa
    15181 acgtatcaaa gcaatgctta ctcgcttgaa ataatagctt gactgtaagt aaacaattct
    15241 aggaaatatt tggaggaaat aaaacatggc acgtgttaaa ggtggcgttg tatcacgcaa
    15301 acgtcgtaaa cgtattctta aattagcaaa aggttactat ggagctaaac acatcttgtt
    15361 ccgtactgca aaagaacaag taatgaactc ttactactat gcataccgtg accgtcgtca
    15421 gaaaaaacgt gacttccgca aattgtggat cactcgtatc aatgcggcag ctcgtatgaa
    15481 cggactttca tactcacaat tgatgcatgg tttgaaattg gctgagatcg aagttaaccg
    15541 taaaatgctt gctgacttgg ctgttaacga tgcagtagct ttcacagctc ttgcagatgc
    15601 agctaaagca aaacttggta aataacaact gatgagactg gaacaggatt gtccagtctt
    15661 tttaaaaata aaggagaaaa atatggcttc aaaaatgcta cacacttgct tacgagtaga
    15721 aaatcttgaa aaatcaatcg cattttatca agatgctttt ggttttaaag aattgcgtcg
    15781 cagagatttt ccagaccatg ccttcacgat tgtctatcta ggtcttgagg gtgatgacta
    15841 tgagttggag ttgacttata actacgatca cggtccgtat gtggttggtg atgggtttgc
    15901 ccatatcgcc ctcagtacac ctgatcttga ggcacttcat caagaacaca gtgcaaaagg
    15961 ctatgaagtg actgagccaa atggtctacc aggaactaca ccaaactatt actttgtcaa
    16021 agaccctgat ggatataagg tcgaagtcat tcgtgaaaaa taatttcgtg caagttaagt
    16081 agaatattcg ttttttactt gacttttttt agctgaaaga gtatactaat aaaaattcaa
    16141 cctttaaggg gagtccagag agactcacaa ggtgtcagat aaaagaatag tgcaattttc
    16201 tagaggagac tttttgagtg tgctctcttg tgttgtacga ttttaactga ggccttgcac
    16261 tagcaaggtc ttttctttat ctggtcccct taaaatttaa ggaggaaaag ttatgaatcc
    16321 cacatgtaag aagcgtttgg gtgtcattcg gttggaaacc atgaaggtgg ttgcacaaga
    16381 ggaaatcgcg ccagcaatct ttgaattagt cctagaagga gaaatggttg aagccatgcg
    16441 agcaggccaa tttcttcatc tgcgtgtacc agacgatgcc catcttttac gtcgtcctat
    16501 ttcaatttcg tctattgaca aggcaaacaa gcagtgtcac ctcatttatc ggattgaggg
    16561 agctgggact gcaatttttt caaccttaag tcagggagac actcttgatg tgatggggcc
    16621 tcagggaaat ggttttgact tgtctgacct tgatgagcag aatcaggttc tccttgttgg
    16681 tggtgggatt ggtgttccac ccttgcttga ggtggccaag gaattgcatg aacgtggagt
    16741 gaaagtagtg acagtcctcg gttttgctaa taaggatgct gttattttga aaacggaatt
    16801 ggctcagtat ggtcaggtct ttgtaacgac agatgatggt tcttatggca tcaagggaaa
    16861 tgtttccgtt gttatcaatg atttagatag tcagtttgat gctgtttact cgtgtggggc
    16921 tccaggaatg atgaagtata tcaatcaaac ctttgatgat cacccaagag cctatttatc
    16981 tctggaatct cgtatggctt gtgggatggg agcttgctat gcctgtgttc taaaagtacc
    17041 agaaagcgag acggtcaacc aacgcgtctg tgaagatggt cctgttttcc gcacaggaac
    17101 agttgtatta taaggagaaa attatgacta caaatcgatt acaagtgtct ctacctggtt
    17161 tggatttgaa aaatccgatt attccagcat caggttgttt tggctttgga caagagtatg
    17221 ccaagtacta tgatttaaac cttttaggtt ctattatgat caaggcgaca acccttgaac
    17281 cacgttttgg gaacccaact ccaagagtag cagagacgcc tgctggtatg ctcaatgcaa
    17341 ttggcttgca aaatcctggt ttagaggttg ttttggctga aaagctacct tggctggaaa
    17401 gagaatatcc aaatcttcct attattgcca atgtagctgg tttttcaaaa caagagtatg
    17461 cagctgtttc tcatgggatt tccaaggcaa ctaatgtaaa agctatcgag ctcaatattt
    17521 cttgtcccaa tgttgaccac tgtaatcatg gacttttgat tggtcaagat ccagatttgg
    17581 cttatgatgt ggtgaaagca gctgtggaag cctcagaagt gccagtttat gtcaaattaa
    17641 ccccgagtgt gaccgatatc gttactgtcg caaaagctgc agaagatgcg ggagcaagtg
    17701 gcttgaccat gatcaatact ctggttggaa tgcgctttga cctcaaaacc agaaaaccaa
    17761 tcttggccaa tggaacaggt ggaatgtcag gtccagcagt ctttccagta gccctcaaac
    17821 tcatccgcca agtagcccaa acaacagacc tgcctatcat tggaatgggg ggagtggatt
    17881 cggctgaagc tgccctagaa atgtatctgg ctggggcatc tgctatcgga gttggaacag
    17941 ctaactttac caatccttat gcctgccctg acatcatcga aaatttacca aaagtcatgg
    18001 ataaatacgg tattagcagt ctggaagaac tccgtcagga agtaaaagag tctctgaggt
    18061 aaactgcaat caatctgttc ttgatttttt attagtttgt aatatgaatt taggagaatt
    18121 ttggtacaat aaaataaata agaacagagg aagaaggtta atgaagaaag taagatttat
    18181 ttttttagct ctgctatttt tcttagctag tccagagggt gcaatggcta gtgatggtac
    18241 ttggcaagga aaacagtatc tgaaagaaga tggcagtcaa gcagcgaatg agtgggtttt
    18301 tgatactcat tatcaatctt ggttctatat aaaagcagat gctaactatg ctgaaaatga
    18361 atggctaaag caaggtgacg actattttta cctcaaatct ggtggctata tggccaaatc
    18421 agaatgggta gaagacaagg gagcctttta ttatcttgac caagatggaa agatgaaaag
    18481 aaatgcttgg gtaggaactt cctatgttgg tgcaacaggt gccaaagtaa tagaagactg
    18541 ggtctatgat tctcaatacg atgcttggtt ttatatcaaa gcagatggac agcacgcaga
    18601 gaaagaatgg ctccaaatta aagggaagga ctattatttc aaatccggtg gttatctact
    18661 aacaagtcag tggattaatc aagcttatgt gaatgctagt ggtgccaaag tacagcaagg
    18721 ttggcttttt gacaaacaat accaatcttg gttttacata aaagaaaatg gaaactatgc
    18781 tgataaagaa tggattttcg agaatggtca ctattattat ctaaaatctg gtggctacat
    18841 ggcagccaat gaatggattt gggataagga atcttggttt tatctcaaat ttgatgggaa
    18901 aatagctgaa aaagaatggg tctacgattc tcatagtcaa gcctggtact acttcaaatc
    18961 cggtggttac atgacagcca atgaatggat ttgggataag gaatcttggt tttacctcaa
    19021 gtctgatggc aaaatggctg aaaaagaatg ggtctacgat tctcatagtc aagcctggta
    19081 ctacttcaaa tctggtggtt acatggcgaa aaatgagaca gtagatggtt atcagcttgg
    19141 aagcgatggt aaatggcttg gaggaaaagc tacaaatgaa aatgctgctt actatcaagt
    19201 agtgcctgtt acagccaatg tttatgattc agatggtgaa aagctttcct atatatcgca
    19261 aggtagtgtc gtatggctag ataaggatag aaaaagtgat gacaagcgct tggctattac
    19321 tatttctggt ttgtcaggct atatgaaaac agaagattta caagcgctag atgctagtaa
    19381 ggactttatc ccttattatg agagtgatgg ccaccgtttt tatcactatg tggctcagaa
    19441 tgctagtatc ccagtagctt ctcatctttc tgatatggaa gtaggcaaga aatattattc
    19501 ggcagatggc ctgcattttg atggttttaa gcttgagaat cccttccttt tcaaagattt
    19561 aacagaggct acaaactaca gtgctgaaga attggataag gtatttagtt tgctaaacat
    19621 taacaatagc cttttggaga acaagggcgc tacttttaag gaagccgaag aacattacca
    19681 tatcaatgct ctttatctcc ttgcccatag tgccctagaa agtaactggg gaagaagtaa
    19741 aattgccaaa gataagaata atttctttgg cattacagcc tatgatacga ccccttacct
    19801 ttctgctaag acatttgatg atgtggataa gggaatttta ggtgcaacca agtggattaa
    19861 ggaaaattat atcgataggg gaagaacttt ccttggaaac aaggcttctg gtatgaatgt
    19921 ggaatatgct tcagaccctt attggggcga aaaaattgct agtgtgatga tgaaaatcaa
    19981 tgagaagcta ggtggcaaag attagtacta taagtgaata tgatttgagt gaatagtaag
    20041 ttaaaaatcc tgatttcaag taaaatcagg attttttcat ggatgcaatt tttttggagt
    20101 ctggtgtgac gcggagggtc ttttgtcctg tgtaagtgac aaagccgggt tttccaccag
    20161 ttggtttatt gagttttttg acttcaatca tatctacctg caccagattc gacaggcgcc
    20221 cttgagagaa gtaggcagct aactctgctg cgtctgtctt gactgcatca gatgggtcaa
    20281 gatttcctga gatgacaaca tggcttccag gaatgtcctt agcatggaac caaagttcct
    20341 ccttgcgggc cattttaaag gtcaattcct cattttgaag attgtttcgt ccgacataga
    20401 tgatggtttt gccatcgctt gctagatatt gttctagttt tttgcgtttc tggattttct
    20461 cccgttgtct tctgcggata aaacctgttt gaatcaattc ttcacggatt tcagcgattt
    20521 cttccagtcc agcttggttg aggacggttt ctacactttc cagatagaga atagtggctt
    20581 tggtttcttc aatcaaatca gtcaagtatt tgacagcttc tttgagtttc tgataccgtt
    20641 taaaatagcg ttgggcattc tggttgggag tcagagcctt atcaagcgca atcatgatag
    20701 gttggttggt atagtagttg tctaggataa cctggtcttg gtcgttaggc acttggtgga
    20761 ggaaggttgt cagcaattct cctttttgac gaaattcttc agcgttgtct gtcgccagta
    20821 actctttttc ctgttttttg agtttgtgtc ggtttttctg aagttcattt tcaacacgac
    20881 gaatcagttc actggcctgc tgtttgacgc ggtcgcgctc agccttatcc ttatagtagg
    20941 tgtccaacaa atcagaaaga tttgcaagag gctctcccac ctgatttgca aaaggaactg
    21001 gactgaagga agtctcagtc aagcatggct tggtttcttg attgaaaaaa tttcggaaag
    21061 cggaaagttt ttcactaacc agtatccttt ccaattcatt tgccgtatcg cgtcccagac
    21121 cttgaaagag gctttgaaga ttttttgctg ttagttcttg ggtttgcagg atttcaaaga
    21181 gcttttcatc cttgatagta aaaggattga gagattttgt acttggcgga gcgatatagg
    21241 tcgatcctgg aagtaaggtg cggtagctat tttgtgaaaa gccgacgtgt ttgataactt
    21301 cgaggatttt atgactgctt ttatcgacca gtagaatatt actgtgtttc cccataattt
    21361 cgataatcaa ggtagcctgg atatggtctc caatctcgtt tttattggaa actgtaattt
    21421 ccacaatacg gtcattttcc acttgctcaa tcgactcaat cagggccccc tgcaaatact
    21481 ttctcaaaac catgataaag gtagaaggtt gggctggatt ttcaaaagtc gtttgggtca
    21541 gctgaatgcg tccaaaaact ggatgggcag aaaggagcag gcgatggctt tggcgattgc
    21601 tgcggatttg caagaccaac tcttgttcaa aaggctgatt gattttctgg atgcgaccat
    21661 tcactaattc gcttcgcaat tcctcaacta tgtggtgtaa aaaaaatccg tcaaatgaca
    21721 tcgttctctc cttgtgattg tattccatag tattatatca aaaaggtaga ataaaatcat
    21781 ggaaatgtgg tataataaag ccaagtaaag agaaacgaga agcacatgta tattgaaatg
    21841 gtagatgaaa ctggtcaagt ttcaaaagaa atgttgcaac aaacccaaga aattttggaa
    21901 tttgcagccc aaaaattagg aaaagaagac aaggagatgg cagtcacttt tgtgaccaat
    21961 gagcgtagtc atgaacttaa tctggggtac cgtgacaccg accgtccgac agatgtcatc
    22021 agccttgagt ataaaccaga attggaaatt gcctttgacg aagaggattt gcttgaaaat
    22081 ccagaattgg cagagatgat gtctgagttt gatgcctata ttggggaatt gttcatctct
    22141 atcgataagg ctcatgagca ggccgaagaa tatggtcaca gctttgagcg tgagatgggc
    22201 ttcttggcag tacacggctt tttacatatt aacggctatg atcactatac tccggaagaa
    22261 gaagcggaga tgttcggttt acaagaagaa attttgacag cctatggact cacaagacaa
    22321 taaacgaaaa tggaaaaatc gtgacctgat atccagttta gaatttgcca tcacagggat
    22381 ttttactgct atcaaggaag aacgcaatat gcgaaaacat gcagtgacgg ctctagtggt
    22441 catccttgca ggttttggtt ttcaggtgtc acgaatcgaa tggctctttc tcctattgag
    22501 cattttcttg gtggtagcct ttgaaattat caattctgct atcgaaaatg tggtggattt
    22561 ggccagtcac tatcactttt ccatgctggc taaaaatgcc aaggatatgg cggctggcgc
    22621 ggtattagtg gtttctcttt ttgcagcctt aacaggcgca ttgatttttc tcccacgaat
    22681 ctgggattta ttattttaaa cagtaagagg aaattatgac ttttaaatca ggctttgtag
    22741 ccattttagg acgtcccaat gttgggaagt caaccttttt aaatcacgtt atggggcaaa
    22801 agattgccat catgagtgac aaggcgcaga caacgcgcaa taaaatcatg ggaatttaca
    22861 cgactgataa ggagcaaatt gtctttatcg acacaccagg gattcacaaa cctaaaacag
    22921 ctctcggaga tttcatggtt gagtctgcct acagtaccct tcgcgaagtg gacactgttc
    22981 ttttcatggt gcctgctgat gaagcgcgtg gtaaggggga cgatatgatt atcgagcgtc
    23041 tcaaggctgc caaggttcct gtgattttgg tggtgaataa aatcgataag gtccatccag
    23101 accagctctt gtctcagatt gatgacttcc gtaatcaaat ggactttaag gaaattgttc
    23161 caatctcagc ccttcaggga aataacgtgt ctcgtctagt ggatattttg agtgaaaatc
    23221 tggatgaagg tttccaatat ttcccgtctg atcaaatcac agaccatcca gaccgtttct
    23281 tagtttcaga aatggttcgc gagaaagtct tgcacctaac tcgtgaagag attccgcatt
    23341 ctgtagcagt agttgttgac tctatgaaac gagacgaaga gacagacaag gttcacatcc
    23401 gtgcaaccat catggtcgag cgcgatagcc aaaaagggat tatcatcggt aaaggtggcg
    23461 ctatgcttaa gaaaatcggt agcatggccc gtcgtgatat cgaactcatg ctaggagaca
    23521 aggtcttcct agaaacctgg gtcaaggtca agaaaaactg gcgcgataaa aagctagatt
    23581 tggctgactt tggctataat gaaagagaat actaagtaga ggtgggctca tgcctgcttc
    23641 ttgtttttac agaaggagga cttatgcctg aattacctga ggttgaaacc gtttgtcgtt
    23701 gcttagaaaa attgattata ggaaagaaga tttcgagtat agaaattcgc taccccaaga
    23761 tgattaagac ggatttggaa gagtttcaaa gggaattgcc tagtcagatt atcgagtcaa
    23821 tgggacgtcg tggaaaatat ttgctttttt atctgacaga caaggttttg atttcccatt
    23881 tgcggatgga gggcaagtat ttttactatc cagaccaagg acctgaacgc aagcatgccc
    23941 atgttttctt tcattttgaa gatggtggca cgcttgttta tgaggatgtt cgcaagtttg
    24001 gaaccatgga actcttggtg cctgaccttt tagacgccta ctttatttct aaaaaattag
    24061 gtcctgaacc aagcgaacaa gactttgatt tacaggtctt tcaatctgcc cttgccaagt
    24121 ccaaaaagcc tatcaaatcc catctcctag accagacctt ggtagctgga cttggcaata
    24181 tctatgtgga tgaggttctc tggcgagctc aggttcatcc agctagatct tcccagactt
    24241 tgacagcaga agaagcgaca gctattcatg accaaaccat tgctgttttg agccaggctg
    24301 ttgaaaaagg cggttccacc attcggacct ataccaatgc ctttggggaa gatggaagca
    24361 tgcaggattt tcatcaggtc tatgataaga ctggtcaagg atgtgtacgc tgtggtacca
    24421 tcattgagaa aattcaacta ggtggacgtg gaacccactt ttgtccaaac tgtcaaagga
    24481 gggactgatg ggaaaaatca tcggaatcac tgggggaatt gcctctggta agtcaactgt
    24541 gacaaatttt ctaagacagc aaggctttca agtagtggat gccgacgcag tcgtccacca
    24601 actacagaaa cctggtggtc gtctgtttga ggctctagta cagcactttt ggcaagaaat
    24661 cattcttgaa aacggagaac tcaatcgccc tctcctagct agtctcatct tttcaaatcc
    24721 tgatgaacga gaatggtcta agcaaattca aggggagatt atccgtgagg aactggctac
    24781 tttgagagaa cagttggctc agacagaaga gattttcttc atggatattc ccctactttt
    24841 tgagcaggac tacagcgatt ggtttgctga gacttggttg gtctatgtgg accgagatgc
    24901 ccaagtagaa cgcttaatga aaagggacca gttgtccaaa gatgaagctg agtctcgtct
    24961 ggcagcccag tggcctttag aaaaaaagaa agatttggcc agccaggttc ttgataataa
    25021 tggcaatcag aaccagcttc ttaatcaagt gcatatcctt cttgagggag gtaggcaaga
    25081 tgacagagat taactggaag gataatctgc gcattgcctg gtttggtaat tttctgacag
    25141 gagccagtat ttctttggtt gtacctttta tgcctatctt cgtggaaaat ctaggtgtag
    25201 ggagtgagca agtcgctttt tatgcaggct tagcaatttc tgtctctgct atttccgcgg
    25261 cgctcttttc tcctatttgg ggtattcttg ctgacaaata cggccgaaaa cccatgatga
    25321 ttcgggcagg tcttgctatg actatcacta tgggaggctt ggcctttgtc ccaaatatct
    25381 attggttaat ctttcttcgt ttactaaacg gtgtatttgc aggttttgtt cctaatgcaa
    25441 cggcactgat agccagtcag gttccaaagg agaaatcagg ctctgcctta ggtactttgt
    25501 ctacaggcgt agttgcaggt actctaactg gtccctttat tggtggcttt atcgcagaat
    25561 tatttggcat tcgtacagtt ttcttactgg ttggtagttt tctattttta gctgctattt
    25621 tgactatttg ctttatcaag gaagattttc aaccagtagc caaggaaaag gctattccaa
    25681 caaaggaatt atttacctcg gttaaatatc cctatctttt gctcaatctc tttttaacca
    25741 gttttgtcat ccaattttca gctcaatcga ttggccctat tttggctctt tatgtacgcg
    25801 atttagggca gacagagaat cttctttttg tctctggttt gattgtgtcc agtatgggct
    25861 tttccagcat gatgagtgca ggagtcatgg gcaagctagg tgacaaggtg ggcaatcatc
    25921 gtctcttggt tgtcgcccag ttttattcag tcatcatcta tctcctctgt gccaatgcct
    25981 ctagccccct tcaactagga ctctatcgtt tcctctttgg attgggaacc ggtgccttga
    26041 ttcccggggt taatgcccta ctcagcaaaa tgactcccaa agccggcatt tcgagggtct
    26101 ttgccttcaa tcaggtattc ttttatctgg gaggtgttgt tggtcccatg gcaggttctg
    26161 cagtagcagg tcaatttggc taccatgctg tcttttatgc gacgagcctt tgtgttgcct
    26221 ttagttgtct ctttaacctg attcaatttc gaacattatt aaaagtaaag gaaatctagt
    26281 gcgagtaaaa attaatctca aatgctcctc ttgtggcagt atcaattacc taaccagtaa
    26341 aaattcaaaa acccatccag acaagattga ggttttaaag tattgtccca aggaaagaaa
    26401 agtaacccta catcttgaat ctaagtagat tttatggtaa aataataggg attttaagga
    26461 gtttgatatg tataacctat tattaaccat tttattagta ttatctgttg tgattgtgat
    26521 tgcaattttc atgcaaccaa ccaaaaacca atccagcaat gtatttgatg ccagttcagg
    26581 tgatttgttt gaacgtagta aagctcgcgg ttttgaagct gtaatgcagc gtttgacagg
    26641 gattttagtc tttttctggc tagccattgc cttagcattg acggtattat caagtagata
    26701 agaaaataat gggcaggact aggtctttgc ctctttttat ttttaaagga tgtttgagaa
    26761 ggttttacag taaaagaaaa ttaaaaaatc tagaaagaaa atatgaaaga tagaataaaa
    26821 gaatatttac aagacaaggg aaaggtgact gttaatgatt tggctcaggc tttgggaaaa
    26881 gacagttcca aggattttcg tgagttgatt aaaaccttgt ccttaatgga aagaaagcac
    26941 caaattcgtt ttgaagaaga tggtagtctg acattagaaa ttaagaaaaa acatgagatt
    27001 accctcaagg ggatttttca tgcccataaa aatggctttg gctttgttag tctggaaggc
    27061 gaggaggacg acctttttgt agggaaaaat gatgtcaact atgctattga tggtgatacc
    27121 gtcgaggtag tgattaagaa agtcgctgac cgcaataagg gaacagcagc agaagccaaa
    27181 attattgata tcctagaaca cagtttgaca acagttgtcg ggcaaatcgt tctggatcag
    27241 gaaaaaccta agtatgctgg ctatattcgt tcaaaaaatc agaaaatcag tcaaccgatt
    27301 tatgttaaga aaccagccct aaaattagaa ggaacagaag ttctcaaagt ctttatcgat
    27361 aaatacccaa gcaagaaaca tgatttcttt gtcgcgagtg ttctcgatgt agtgggacac
    27421 tcaacggatg tcggaattga tgttcttgag gtcttggaat caatggacat tgtatccgag
    27481 tttccagaag ctgttgttaa ggaagcagaa agtgtgcctg atgctccgtc tcaaaaggat
    27541 atggaaggtc gtctggatct aagagatgaa attaccttta ccattgacgg tgcggatgcc
    27601 aaggacttgg acgatgcagt gcatatcaag gctctgaaaa atggcaatct ggagcttggg
    27661 gttcacatcg cagatgtttc ttattatgtg accgaggggt ctgcccttga caaggaagcc
    27721 cttaaccgtg cgacttctgt ttacgtgaca gaccgagtgg tgccaatgct tccagaacga
    27781 ctatcaaatg gcatctgctc tctcaatccc caagttgacc gcctgaccca gtctgctatt
    27841 atggagattg ataaacatgg tcgtgtggtc aactatacca ttacacaaac agttatcaag
    27901 accagttttc gtatgaccta tagcgatgtc aatgatatcc tagctggcga tgaagaaaag
    27961 agaaaagaat atcataaaat tgtatcaagt atcgaactca tggccaagct tcatgaaact
    28021 ttagaaaaca tgcgtgtgaa acgtggagct ctcaattttg ataccaatga agcgaagatt
    28081 ttagtggata aacaaggtaa gcctgttgat atcgttcttc ggcagcgtgg tattgccgag
    28141 cggatgattg agtcttttat gttgatggct aatgaaacag ttgccgaaca tttcagcaag
    28201 ttggatttgc cttttatcta tcgaattcac gaggagccta aggctgaaaa ggttcagaag
    28261 tttattgatt atgcttcgag ttttggcttg cgcatttatg gaactgccag tgagattagt
    28321 caggaggcac ttcaagacat catgcgtgct gttgagggag aaccttatgc agatgtattg
    28381 tccatgatgc ttcttcgctc tatgcagcag gctcgttatt cggagcacaa tcacggccac
    28441 tatggactag ctgctgacta ttatactcac tttaccagtc caattcgtcg ttatccagac
    28501 cttcttgttc accgtatgat tcgggattac ggccgttcta aggaaatagc agagcatttt
    28561 gaacaagtga ttccagagat tgcgacccag tcttccaacc gtgaacgtcg tgccatagaa
    28621 gctgagcgtg aagtcgaagc catgaaaaag gctgagtata tggaagaata cgtgggtgaa
    28681 gagtatgatg cagttgtatc aagtattgtc aaattcggtc tctttgtcga attgccaaac
    28741 acagttgaag gcttgattca catcactaat ctacctgaat tttatcattt caatgagcgt
    28801 gatttgactc ttcgtggaga aaaatcaggt atcactttcc gagtgggtca gcagatccgt
    28861 atccgtgttg aaagagcgga taaaatgact ggagagattg atttttcatt cgtacctagt
    28921 gagtttgatg tgattgaaaa aggcttgaaa cagtctagtc atagtggcag agggcgtggt
    28981 tcaaatcgtc gttcggataa gaaggaagac aagagaaaat caggacgctc aaatgataag
    29041 cgtaagcatt cacaaaaaga caagaagaaa aaaggaaaga aaccttttta caaggaagta
    29101 gctaagaaag gagccaagca tggcaaaggg cgagggaaag gtcgtcgcac aaaataaaaa
    29161 ggcacgccac gactatacaa tcgtagatac gctagaggca gggatggtcc tgactggaac
    29221 tgaaatcaag agtgtacgag ctgctcgaat taatctcaag gatggctttg ctcaagtgaa
    29281 aaatggagaa gtttggctga gcaatgttca tatcgcgcct tacgaagagg gcaatatctg
    29341 gaaccaggaa ccagaacgtc gtcgtaaact cctgctccat aaaaagcaaa ttcaaaaatt
    29401 ggaacaagag accaaaggga caggaatgac cttagttccc cttaaggtct atataaaaga
    29461 tggctacgct aagcttcttt taggacttgc caaagggaag catgactatg acaaacggga
    29521 gtctatcaaa cgtcgtgagc aaaatcgaga tatcgcgcgt gtgatgaaag ctgttaatca
    29581 gcgataaaaa gaggaattga aaatggaaaa attagttgcc tataaacgca tgcctttgtg
    29641 gaataaacaa acaatgcctg aagatgttca gcaaaagcac aatacaaaag ttgggacttg
    29701 ggggaaaatt actgtcttga agggagctct caagtttatt gaattgacag aagaagggga
    29761 agttctagct gaacacctct ttgaagcagg ggcagacaat ccaatggccc aacctcaagc
    29821 ctggcaccga gtggaagctg ccacagatga tgtggaatgg tacttggaat tttattgtaa
    29881 acctgaggat tattttgcta aaaaatacaa taccaatcct gttcattcag aggtcctaga
    29941 ggccatgcag acagtgaaac aagggaaagc tttggatttg ggttgtggtc aggggcgtaa
    30001 ttctcttttt ctagcccagc aagattttga tgtgacggct gtagatcaaa atggactagc
    30061 tcttgaaatc ttgcaaagca ttgtggagca ggaagatttg gacatgcctg ttggccttta
    30121 cgatatcaat tcagctagca ttgaacaaga atatgatttt atcgtttcaa cagttgttct
    30181 catgtttcta caagcggacc gcattccagc tattattcaa aatatgcagg agaaaaccag
    30241 tgttggtggt tacaacctta tcgtttgtgc catggacacg gaggattatc cttgctcggt
    30301 taatttccca ttcaccttta aagaaggaga actggcagac tattacaagg attgggaatt
    30361 ggttaagtac aatgaaaatc caggccattt gcaccgtcgc gatgagaatg gcaatcgtat
    30421 tcaactacgc tttgcgacct tactagctaa gaaaatcaag taaacacaca tgaagattag
    30481 gaattttcct gatctttttt cttttttacg aatgatatag aaaaggaggg aattcatgtt
    30541 tgttgcgaga gatgctaggg gagaattggt aaatgtgtta gaggataaac ttgagaagca
    30601 agcatacacc tgcccagctt gtggaggcca gctccatttg cgtcaaggac caagtgtacg
    30661 gacgcatttt gcccataaat ccttaaaaga ctgtgatttt ttctttgaaa atgaaagtcc
    30721 agaacacctg gccaataagg aatccctcta tcactggttg aaaaaagaga caaaggttca
    30781 attagagtac ccgctttcag aacttaaaca gattgcggat gtatttgtaa atggcaatct
    30841 agctctagaa gttcagtgta gtcccttgcc tcagaaagtc cttaaagagc gaagtgaggg
    30901 atatcgtagt cagggttacc aagtactgtg gttgctgggt caaaaactgt ggctcaagga
    30961 gcgtttgact cgtctacagc aaggttttct ttatttcagt caaaacatgg gcttttatgt
    31021 ttgggaatta gacaaggaaa aacaagtttt aagactcaaa tacctgattt accaggatct
    31081 ccgcggtaaa ctccattatc aaatcaagga attttcctat ggtcaaggta
//
LOCUS       DAVAZT010000022        31002 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVAZT010000022 DAVAZT010000000
VERSION     DAVAZT010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31002
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.022"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(298..516)
                     /locus_tag="VQT45_000947"
     CDS             complement(298..516)
                     /locus_tag="VQT45_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2359289.1"
                     /translation="MVLNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(762..1040)
                     /locus_tag="VQT45_000948"
     CDS             complement(762..1040)
                     /locus_tag="VQT45_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359290.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEMLELACWFRVIIVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYSIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(1254..2885)
                     /gene="rlmD"
                     /locus_tag="VQT45_000949"
     CDS             complement(1254..2885)
                     /gene="rlmD"
                     /locus_tag="VQT45_000949"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET2359291.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSLHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWCTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSQKNASLNKITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2959..3933)
                     /locus_tag="VQT45_000950"
     CDS             complement(2959..3933)
                     /locus_tag="VQT45_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HET2359292.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(4007..4621)
                     /gene="pmp23"
                     /locus_tag="VQT45_000951"
     CDS             complement(4007..4621)
                     /gene="pmp23"
                     /locus_tag="VQT45_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HET2359293.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(4621..5595)
                     /locus_tag="VQT45_000952"
     CDS             complement(4621..5595)
                     /locus_tag="VQT45_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HET2359294.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQKENGTYSILIKNIEDIQSK"
     gene            complement(5603..6859)
                     /locus_tag="VQT45_000953"
     CDS             complement(5603..6859)
                     /locus_tag="VQT45_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HET2359295.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(6921..7352)
                     /locus_tag="VQT45_000954"
     CDS             complement(6921..7352)
                     /locus_tag="VQT45_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2359296.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(7354..7956)
                     /locus_tag="VQT45_000955"
     CDS             complement(7354..7956)
                     /locus_tag="VQT45_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HET2359297.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPTYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7940..8779)
                     /gene="prmC"
                     /locus_tag="VQT45_000956"
     CDS             complement(7940..8779)
                     /gene="prmC"
                     /locus_tag="VQT45_000956"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HET2359298.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(8779..9858)
                     /gene="prfA"
                     /locus_tag="VQT45_000957"
     CDS             complement(8779..9858)
                     /gene="prfA"
                     /locus_tag="VQT45_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HET2359299.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(9855..10445)
                     /locus_tag="VQT45_000958"
     CDS             complement(9855..10445)
                     /locus_tag="VQT45_000958"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HET2359300.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRGLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            10568..10750
                     /locus_tag="VQT45_000959"
     CDS             10568..10750
                     /locus_tag="VQT45_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HET2359301.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            10887..12260
                     /gene="mnmE"
                     /locus_tag="VQT45_000960"
     CDS             10887..12260
                     /gene="mnmE"
                     /locus_tag="VQT45_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HET2359302.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNIRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEANLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLIEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(12307..13242)
                     /gene="dapA"
                     /locus_tag="VQT45_000961"
     CDS             complement(12307..13242)
                     /gene="dapA"
                     /locus_tag="VQT45_000961"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HET2359303.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(13298..14374)
                     /locus_tag="VQT45_000962"
     CDS             complement(13298..14374)
                     /locus_tag="VQT45_000962"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HET2359304.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(14716..14788)
                     /locus_tag="VQT45_000963"
     tRNA            complement(14716..14788)
                     /locus_tag="VQT45_000963"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14753..14755),aa:Thr,seq:ggt)
     gene            complement(14888..15397)
                     /locus_tag="VQT45_000964"
     CDS             complement(14888..15397)
                     /locus_tag="VQT45_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HET2359305.1"
                     /translation="MKKLTIRDIADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(15395..15491)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            15520..15951
                     /locus_tag="VQT45_000965"
     CDS             15520..15951
                     /locus_tag="VQT45_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HET2359306.1"
                     /translation="MKIPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKAYIFRK"
     gene            16033..16410
                     /gene="mscL"
                     /locus_tag="VQT45_000966"
     CDS             16033..16410
                     /gene="mscL"
                     /locus_tag="VQT45_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HET2359307.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(16452..17546)
                     /gene="hemH"
                     /locus_tag="VQT45_000967"
     CDS             complement(16452..17546)
                     /gene="hemH"
                     /locus_tag="VQT45_000967"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HET2359308.1"
                     /translation="MKKAILMMTFGSPEEISFEGVAEFFTNIRRGVRPQDHEIQTLYD
                     NYIRIGGTPLQRITREEVNLVKERLGEEYGIYFANKFSRPFIPDVIKQMETDGVEECI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEVLLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            complement(17624..18456)
                     /gene="srtG2"
                     /locus_tag="VQT45_000968"
                     /pseudo
     CDS             complement(17624..18456)
                     /gene="srtG2"
                     /locus_tag="VQT45_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000218039.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG2"
     gene            complement(18534..19532)
                     /gene="srtG1"
                     /locus_tag="VQT45_000969"
     CDS             complement(18534..19532)
                     /gene="srtG1"
                     /locus_tag="VQT45_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000851047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG1"
                     /protein_id="HET2359309.1"
                     /translation="MKTKREKPKKSLSRRLVLAVDGVINHLLLIFAALIFLFGFYALW
                     DSNQVYSLASSSEYEAYRPVTTQQDELASFSGFSKLQELNPEVLGWINVYGTNIDYPL
                     VQAKDNEKYLNKDSKGEFAATGAIFLDARNNPKFEDFNTIIYGHHVENGVMFGDVAKF
                     ADQEFFDQHRYGSIYYNGVEKGLEIFEMLEVDAYDFNIYDPGIQGEDRQQAYLDHLLS
                     VAMHKRDISLSPSDRIILLSTCFLDVTNGRHIVVAKITDTVPKNTFHTKKSKPFPYSV
                     FDDSSLGRFLSSIPLWIWYLILFVLFLLLIFLLLVLYLILRRRRESKKNARSRPFY"
     gene            complement(19550..20746)
                     /gene="pitB"
                     /locus_tag="VQT45_000970"
     CDS             complement(19550..20746)
                     /gene="pitB"
                     /locus_tag="VQT45_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus major pilin PitB"
                     /protein_id="HET2359310.1"
                     /translation="MKKTFFKKLFTASIAAITALSVFRGVPTFADDNSAITKANGENN
                     AVVKINKTLNIAEGITTPTATFTFKFTEKTGQSSNGAPYQTGVAIPDRNVEYNKNDHP
                     TADKIQKATEDIFSGVAYGHAGEYVYDVAEAKTGWQAITKNGKTIDAMRYDKRTYEMH
                     VIVKNKVNGGVYISSVYFKENNKSNAPKVEPSEQGVYNLFDNTYTKDASKEPNPDDPS
                     QVDPNAKALTITKKVDGASGDKTRDFQFHIKIQLPSTNKTAETPVTNIIVKHGSKSEV
                     LAVVTPADTVEYNFTLKDGETFTVEQLPAGSKYTVTETGVAGYTDSSIYTTNGAEQTS
                     QGQKNVDFTLTDILIGEKKNDNKVTNKIDDVTPTGLLIDNLPFILMIGLGLAGFVVLS
                     KKRREA"
     gene            complement(20791..21342)
                     /gene="sipA"
                     /locus_tag="VQT45_000971"
     CDS             complement(20791..21342)
                     /gene="sipA"
                     /locus_tag="VQT45_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system signal peptidase SipA"
                     /protein_id="HET2359311.1"
                     /translation="MLLKKKHKKPVTQVNRDKSPPSVWGDILYLVSKLLMVGFVLAIL
                     YFFVFGLLRYNDDGMKPALKDGDLVVYYRLDKRYSIGDLLVYSYKGKERVARVIATEG
                     STIDINENGLIINGSPQQEQDIYKETLLYKEGATFPMKVPAGQLFVLGDNRTTAVDSR
                     AFGTIPIQDTQGKVVTVIRRRGF"
     gene            complement(21342..23105)
                     /locus_tag="VQT45_000972"
     CDS             complement(21342..23105)
                     /locus_tag="VQT45_000972"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359312.1"
                     /translation="MIDTPYWFTSGLERGMLNISSLIAPKIDGFYSIKFRYYIGSNDS
                     ITSLKGYISGYNSGIPNEIFSANNENDLQQKFKEITDKILPLGVHHVTISDVLSKYVQ
                     LLPGDASHLRVVKIKDGNEQELNDNQVTIETKKNEQGLVEVTAKFNPSYTLEDDAKYV
                     LKFTVTSSQEAFDAIAGDKTLTSDDAEEADATKLYSNKGAKVAYSYGIGTSRTKIKDY
                     SEKPTFKPSDPLTVPVEIEWKGVDGKSNPSANRPPSVELNLNQKKDGSIKDSYRKVTS
                     PVQTNSFTENTSFAKVAKGYDYELKAPDAPGYTVEVQKTGTKEKPSFKVIYRQLPSLT
                     VKKILEGEQSPNKSFTINVTFSDKDGKPINGKFGNTTVTNGKAQISLKNSQETALSYL
                     PRDTHYKVEEVENSRTGYHVTYEKQEGTLSEDVQTIVTNHRLPTLSVTKKVTGAFANL
                     LQSFKITINVKDAQNKPLNGSYSAIVNNQKTTLQFTNGKATVDLKKDKTIKILDLPLN
                     ARYSIEEEASSSRGYQVSYDKKEGTLDANKSATVTNNKNSVPETGIDFLSSTLVLGVV
                     LPLGGIFFIILLGHLVVNRRK"
     gene            complement(23427..23930)
                     /locus_tag="VQT45_000973"
     CDS             complement(23427..23930)
                     /locus_tag="VQT45_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin"
                     /protein_id="HET2359313.1"
                     /translation="MNVQYDFKKIQYFTSSLVIFLAILFLCAPINSLRADSITEPQTT
                     LHKTITPISGQKDQYELSLDITSKLGTETQSEPLDVVLVADLSGSMEERDVWSYSSRR
                     YISRIEALKHTLKGVNGRQGLIDTILSNSQNRLSIVGFAGKIDNQYNDRYYNEYYLSY
                     QYGTWPN"
     gene            24289..25512
                     /gene="pepT"
                     /locus_tag="VQT45_000974"
     CDS             24289..25512
                     /gene="pepT"
                     /locus_tag="VQT45_000974"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HET2359314.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPRQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(25548..26177)
                     /locus_tag="VQT45_000975"
     CDS             complement(25548..26177)
                     /locus_tag="VQT45_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359315.1"
                     /translation="MNKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSANSKDKTALLESTKAILVLNHQIQSKVSASEETSPARNAEANSDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            26142..26363
                     /locus_tag="VQT45_000976"
     CDS             26142..26363
                     /locus_tag="VQT45_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359316.1"
                     /translation="MDLFQELICLVQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(26634..26982)
                     /locus_tag="VQT45_000977"
                     /pseudo
     CDS             complement(26634..26982)
                     /locus_tag="VQT45_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(27087..27647)
                     /locus_tag="VQT45_000978"
                     /pseudo
     CDS             complement(27087..27647)
                     /locus_tag="VQT45_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(27873..30992)
                     /gene="phtE"
                     /locus_tag="VQT45_000979"
     CDS             complement(27873..30992)
                     /gene="phtE"
                     /locus_tag="VQT45_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HET2359317.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQISQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         8835 a         6360 c         5686 g        10121 t
ORIGIN      
        1 aaaaggatct agtttttatt tttagttaaa ttatgtctat atttttcatt aactcatcaa
       61 taaaaatttg tttgctaata tctctttctt ctgattttgt ttcaaggatt attgctacat
      121 cattcatatt tttaggtaaa taccaaccat ctggcttatc tgaatatccc ttgaagccta
      181 attgattaaa agtagttatt tgaccagtac cttgattgat gttttcttca acttcattaa
      241 agcctatact tctcttgcat aatccctaac ttgatcttct gtccttaaag tcattttcta
      301 ttcctcgtca ctaaaattat cttcaaaact aataatatca ttaggagtgc aagataaagc
      361 cttacatatt ctttctaaat tcttaaatgt aattggttta tcctttccca tttgtgccat
      421 aacatttgtt gtaagtcctg ccatagctat tacatctgtt ttctttagtc ctttttttgc
      481 taactgtatc cataatggtt tatagttaag taccataata tccctctttt tttcttcatt
      541 aaatttattt aattatagca taaatattga tttcattcaa tcttacattg atttagtgat
      601 ttgttttaga gaatttgttg tgttattccg tccttatttt gccataaatt gttttaagtg
      661 ggacctctta tccttaccat ttttacctcc taattttgag tataaaaaag acgatagagt
      721 ttttaatttc tatcgtctga gatttacata ttaaattttc atcacaaaat aagactcttt
      781 aaagaatctt taaattcatt ggtatgctgc ttacaatatc cattattaaa atggatacta
      841 taagcagcac accaactatt tattttttga gttttaaact ttggtagaag tcttgaactc
      901 cttatattta cataactatt tgcctctata actattatga cacgaaacca acaagcaagt
      961 tcaagcatct ccatatcttt attcaaatga ggactaagat attcacaaac tttatcataa
     1021 acctctttat cttttttcat aaaaggggca tacaacttag caaatttatc ctaaaatttt
     1081 ttgttgcctt tatcaatcat ttcaacgctc ctttaaatat aaaaataatc ctatcaatct
     1141 ttatattgag cctattttct aattgatacc ttgcaagaaa ggaataatag ctgttcctat
     1201 accaagtagg aatgtaataa atgcagaaag tcatatactg tcattctttt ctattaaatc
     1261 attttgaagt gtctcaaagc atccatgatg gcttcttctt tttcaggtgt acactgtgga
     1321 ataatttgtt tatccttttt agacttgttg taatgttctc gtaattctat tccacatttc
     1381 ttttttatct gtgcaatata taatgtcgaa acttttaatt caaatttatt ccaaacatat
     1441 tctttgattt gagcatatgt tgctttgctc tccgcacttg tcaaatccat ctcatccagc
     1501 tcaatttcaa cacttatgtg cttatcgaca tcgagtttgg acaaaagtgc taccgtctcg
     1561 acgtgatgcg tttgaggaaa tagatccacc ggctggactt tcttcaattc atatcccaat
     1621 tcttggtaga gtttgatatc acgcgccatg gttgcgacat tgcaggagat ataggcgatg
     1681 cgatcggctc ctgtttgggc gcttgctttg ataaagcttt ctgtcaagcc cttgcgtgga
     1741 ggatcaacca agataacggt tggttgaata ccttccttga gccatttctt catggcattt
     1801 tcagccgtgt cacagacata gtgggcatta gtaatcttgt tcaaagaagc attcttctgg
     1861 ctattctcaa ccgcttctgg aatcagttca acaccgtaga cttctttgac atgcttggcg
     1921 actgataaac caatggttcc aataccagaa taagcatcaa taaccacgtc atcttttttt
     1981 aactctgcaa agtcaatggc tgtttgatag agtttctccg ccatttcagt attgacttgg
     2041 taaaaggctg ggccagcgat ttggaagtca tttcccaaca tctggtccgt aatatagtct
     2101 tgaccataaa gagtgcacca ctccttacca aaaatcgcat tggtattctg gtcgttgata
     2161 ttttgcatga cagacacaat ctctgggaac tgcttgataa cttgttcaat caattggtca
     2221 acacgaaaaa cttttggacg agttgtcacc aaaacgacca tgatttgtcc tgaatagtga
     2281 ccacgacgca ccacaagatt ccgaatcaat ccagactgtt ccttttcgtc ataaggtttt
     2341 aaatcaaaac gacggagcag gtctcgaaga gctactacga cttggtcaat gacaggatcc
     2401 tggataaaga aatcttcaag gggcatgagg ttgtgcgaat tcttacggaa aaatcctgtt
     2461 tccaagacac cattcactcg acgaacgggc acctgcgcct tattgcgata cttgactgga
     2521 tgttccatac caagcgtttc agcaacttct acatctgcaa ttccagcaat cttgtagaga
     2581 ctgtccttga cttgcttggt tttaaacttg agctgttctg gataagaaag gtgtcctaaa
     2641 tccgcgattc ctgaacgcag gtaagccaaa tctagatctt gattacggtg tagtgactgg
     2701 acaaggtatt tttcaacttt tccaaagcca atctttttat tgaccttgag gacacgcatg
     2761 agaatttttt cactcggtaa agcattctct acaaaaaaga ccaaaccatc taccttggca
     2821 actcctgccc cttcatgggt caaatcaaca atttcaactt ctacaatatc atttttcttt
     2881 aacattcttt tctctttcta ttggccgaca aaaaagacgg caacgttacg attaccatcc
     2941 attataccat gaaatttctt aagaaccaaa actcttgaag aagttgacaa gggcttgcca
     3001 gagggagctt aagaagttac caccgtcctc tagcgcctta tccgcatcaa agttaaggtt
     3061 gatattttta aaactgtcgc cagcttgtga tacgatgctt tgtttaaggt catttagggt
     3121 tttagtgaaa tctgcattgc tgaggatatc actctttgag agattcaagg caaaattgat
     3181 gatgatattg atctggtttc ctgttatgac ctgatcaagt ttgtaatttt ttaaggtatc
     3241 ttcaacaatc ttgcggacat cttcttctgt cagatttccc ttgctttctt tagctttggc
     3301 gagtcctgac ttgatatcag ctagggcaac gtttaattta ttagcatcat agcctgattt
     3361 gtccttgttt tcagcattga tatctgacaa agcctttagc tcttcttgag ccaaatcttt
     3421 attggcttgc ggcaccttgg ctccattagc ttctagcgaa tagtagatcc cagccaaagc
     3481 actctcacct gtaactggaa taggggctgc tacagtgatt ttggcatgtt ccatacccag
     3541 cgttactgct gcgtttcggt acatatcctg agtcacctta gtgatatttt ctggtgtttc
     3601 aatcttgacc tcaagtggcg atttgtcacc tagcttttga atcttggctg atgaatacaa
     3661 ctgtaagcta gagtcattgg ccacattcat gattttagaa taaacatcag gtgtcatggt
     3721 cttgagttct ttggtatctg ttgaggcatt gtagcccagt tttttaagag tttgattttt
     3781 ttggtcttca gatagggagg aacctaggac atattcaggt tggacatagg tttcatcgat
     3841 aaccttttga acatctgttg ctgcatggac gctattcata gctgttactg cccacaagac
     3901 cgcagcactg gtcagaaaga gtttctttct catagggaat ttcctccttt acttttctag
     3961 agtaatatat ctatcttaaa gaaaacttat aacaaaaaca cctggtctag ccagatgttg
     4021 aaaagagagt gaaacatttg atgatgtaaa ggttaagtcg tacctgtcta gaataataat
     4081 agtttcctcc atttacatag agttcagcac cgtgaaaaat ggaaatgggg tgaatataac
     4141 tataagtctt tccagtcgta ttaccaagca agggggcaac agtctcacga gagtactgtt
     4201 tggctagagc caaggtattt tccttgccat tttgggcgat aaaatcgata taggcaggtc
     4261 caaaattata ggcttgaaca gctgtccaga tatctacccc cttcttctgc gccagataga
     4321 gattgcctgt cagagtttga atgccttgcc gaatgctaga ggcattatca ttgatggtgt
     4381 tggttgaacc acttgcagac tcactagact gcataacatc gccttctttt ccttttgttt
     4441 cagtataaat catagcaagc acaagctctt cgtttgctgg ggtgtctttt tcactcaaga
     4501 tttctcgcac catgggttga taggtcatga cttgtttgac atcttgatga acgcggtaag
     4561 ctttatagcc agcaaaaagg aagactgcta gtacaagcac tcttcgaatt cgtttaaaca
     4621 ttatttactt tggatatcct cgatattttt gattaagata gagtaggttc cattttcctt
     4681 ttggataaac tcaacagact cggcgtcttg atagacgtta ttgggaacga tgagctcaat
     4741 tccatttgat aaggagagtt tttggttttc aaatttcttt aattggcgac tggcatcaat
     4801 ttcatcaaat tgaacaggtt ctggtacggc ttctttgact tggtcaataa agctcaaacg
     4861 agccgtcaga ttgttgtcaa aaaggtcatt agccaatttc tcaggtgaca attcattgct
     4921 ttcttctagg ttgttgaaaa tcgctgattt gaccttggat tgaaattgaa aatcatctgt
     4981 gttaaaagat tcagcaattc tctgggctgt tttttccagt tccttgatag attttttagg
     5041 agaaatctta ggagcgacag caagaagatt atctgaaaaa tagttcaaaa aagtcccgtt
     5101 gtacttgatt cgtttttcaa tcaggtgata cttgcgactc tgaagattga ccaccaaggc
     5161 ctcgtcagca cccgttccaa atccaggcag gttattctga gtcagcttga ttggattatc
     5221 aacttctcct ccgaggtggg tcaaggtctc ccgcagggca attcgcaaga aagcgaaatg
     5281 ttctacacct tctttagaaa attgaacaaa aatcaagtca ttggtcttga gattttcaga
     5341 aatgctaaac tcctctttcc agagattagc cagcgttact gatgtctcca acaaatcgtc
     5401 tgtaatatga ttgaagaagg gattttcttc ttcgaaaatc ccagtcttgg cttcatctga
     5461 atacacatgt tcaatttttt tacgtaggta ttcttcgatt tttggagtaa tattgagaaa
     5521 cttatctgct aagaacagct cggtatcatc cggactgaac tggtgaataa tggctttctt
     5581 aatataaatg tccataaaag ttttattcct cgtataatgg gaaggcatct gtcaattctt
     5641 tgactgcact tctcacttct tctaatacag cctcattttc tgaattctta agggttttaa
     5701 tgatgagttc agccactttg cgactttctt cttcaccaaa tccacgtgca gtaatagctg
     5761 ctgctccgat acgaatccca cttgtcttga atggtgacaa ggtttcgtaa gggattgaat
     5821 ttttatttag ggtaatattg acttcatcca gcaagttttg agcaactttt ccgttttcta
     5881 caaccttagt cacatcaaca aggaagagat ggttttcagt tccacctgaa ataatacgga
     5941 aatcagggtc ttgcaagaag acatctgcca tagccttgct gttcttaatt acattggcag
     6001 catattcctt gaaggctgga tccaaaactt ctttgaagga aactgcctta gccgccacaa
     6061 catgctctaa aggaccgccc tgaatacctg ggaaaatagc tgaattgatt tttttagcaa
     6121 gttcttcgtc attggtcaaa atcaaaccac cacgaggtcc acgaagggtt ttgtgggtcg
     6181 ttgttgtagt gatatgagcg tatggcactg ggcttgggtg aagaccagct gcaaccaagc
     6241 cagcgatgtg ggccatatca accataagct tcgcaccgac agcatctgcg atttcacgga
     6301 attttgaaaa gtcaataatt tgagaatagg ctgaagcacc agctacaatc agttttggtt
     6361 ttacttcttg ggcttgtttc aagatagcat caaagtctaa gagttccgtt tcaggatcaa
     6421 cactataaga aacaaagttg taggtttgac cagagaagct aacaggagcc ccatgagtca
     6481 aatgaccacc tgatgccaaa tccattccca taaccgtatc acctggctca atcaaggaca
     6541 tgtaagccgc acagttggcc tgacttcctg agtgaggttg gacattggca aatttagcac
     6601 cgaaaatttc ttttgcgcgt tcaatagcaa gagtctctac aacgtctact acatcagttc
     6661 caccataata acggcgtcct gggtaaccct cggcatattt atttgtcaag atagaccctt
     6721 gagctgccat aacagccttg gaaactacgt tttccgaagc aattaactcg atattatttt
     6781 gttggcgttc ttcttctttg gcaatagcat tccagagatc agcatcatat gctttaaaat
     6841 catctttgtc aaaaatcata ggtcttctcc tttattgtgt gactagtcca ttagtttgat
     6901 tttacaataa gaaaatcaaa ctaaaagatg cgaataaacc gtttctgcat tttatcacaa
     6961 gtatagccaa ctttttcata aaatgcatga gcacccagac gatgattggc agaatttaag
     7021 cggataaacc cataaccaca tcttttggct tcttgttcca acccttgtag taaactttta
     7081 ccgatacctt gaccttgcgc ttgaggtgaa actgctaaag ctaagatatt aaatcctgct
     7141 ttggaataga gtgattcgta aacttcagcg tggacatatc caagtaagac atgattagct
     7201 gcatcctcat agccaagtag gaaatgatgg gaatcctgag acagtctagc tagttggcta
     7261 gccgtttcct ctggactaaa agtataaccc aaagcctctt ggttgatgtc acatatcgct
     7321 ttcacatctg tttcttgcaa atctcttagc atttcaagcc tcctcaaaag aaatctctgg
     7381 caaccgagca agaatatctt ctcgtttaat tgcgccttgg cgtaagattt tcaccttgtc
     7441 tccagacaaa tccacaatag ttgaatcctg tccagttaga aaagcatcgt cttccagacc
     7501 cagaacctct tggtcaaaat ccttcagaat ttgttcaaag gttacaccac ttgcctgacc
     7561 tgagatattg gcagacggcc caatcaaggg acctgtctct cgaattaaat ccagtgtgat
     7621 agggtgactg ggcatccgaa atccaatagt tgcaaggtca gaatttaccc aatagggaac
     7681 tcggtcattg gcttcgagaa taatggtcaa gggacctggc aaaaaggtct ctacaagttt
     7741 ttgtagataa gttggctgat tcttagaaaa gtgcaagata tcctcgaaag aggcgatatt
     7801 gagattgagt gccttatctc taggacgacg tttgagttgg taaacatggt caactgcttt
     7861 ttcatctaag gccttggcaa aaagaccata aacagtctct gtaggtagaa cgacagctcc
     7921 accattttcc aactcttgtc taatcctgtc catcatcaac cacaaccatc ctattttgac
     7981 caaattggtc tttgagtgtt cgaacttttt tttcaggaag atgttttcta aaaagttcgg
     8041 gaacactttg accttgcttg tatccaattt caaggtaaat cttaccacca tccttgagat
     8101 agtcttttgc atcttccgca attctacagt aaatagctag gccatcctcg tctgcaaaga
     8161 gagctagatg aggctccgaa tgcaaaacat tcaagcctac ctctgactca tcttcacgag
     8221 agatataggg tggattggat acaattatat catatttttc agaaatttct gcaaaacaat
     8281 cagatttttt aaaaaatata ttaagatttt gatcgctagc attctctgat gcaagctcta
     8341 aggcctcttg agaaacatct gctgctgtca ctgaccaatc tggtctattt tttgctagag
     8401 cgagagcaat agctccacta cctgttccaa tatccagaac tgagagattc gtctcaagat
     8461 tttcagttag aataagctcc actaactcct ctgtttctgg acgaggaatc aaaacccgtt
     8521 catccacctt taaatgcatt ccataaaaat ctgcctgtcc aatgatgtac tgagctggct
     8581 tgtgagctgc tagttgctgg taaatatctt ctacaaattg tttttcttcc tctgttgtca
     8641 cctcctgctg gagggcaaaa ataaagtctg taaaagatag atttttcaga ctacgataga
     8701 caaaagagag gctttccgct tcctctcctt gtcttatcaa ctcttcttca aaatttgaaa
     8761 ataattgagc taatttcatt atttgtttaa ttcttctagt ttttgtgttt ggtcataaag
     8821 caccaaggca tccacaactt cgtccaattt accagacaaa atcgtatcta gtttttggag
     8881 ggtcaagccg atacggtggt ctgtgacacg gttttgaggg aagttataag ttcggatccg
     8941 ttctgaacgg tcaccagtac cgattgtcga cttacgctca gcgtcttgtt catcctgagc
     9001 aatctgagca aagtggtcag cgacgcgtgc acggataatc ttcatagcct tctcacggtt
     9061 cttctgctgg gtacgttctt cctgcatctc aaccttgata ttggttggca agtgaacgat
     9121 acgaacggca gtcgcaacct tattgacgtt ctgtccacca gcacctgatg cgtggtaaat
     9181 atcaacacga agatcttttg gatcgatatc gtattctact tcttcgactt caggcatgac
     9241 aagaactgtg gcagttgagg tatgaacacg accttggctt tctgtcacgg ggacacgctg
     9301 cacacggtgg gcacctgatt cgtacttaag cttagagtat acagactgac ctgaaaccat
     9361 agcaaccact tctttaaacc caccgacacc attcatagag gcttccatga cttcaaagcg
     9421 ccagccttgg gcttccgcat acttttggta catagttagc aaatctccag cgaaaagtgc
     9481 cgcttcgtct ccaccagctg ctccacggat ttcaaggatg atattcttgt catcgtttgg
     9541 atcctttgga aggagcaaaa ttttcagttt ttcttcatat tcttcttttt cagccttggc
     9601 atctttgagt tcttgcttgg ccatttcttc caagtccgca tctccgcctg attccttaat
     9661 catctcttcg gcatcgacga tattttgaag gacttgttta tactcacggt aggctattac
     9721 ggtatcacga ttggaagctt cttcttttga aagctccata aaacgcttgg tgtctgaaac
     9781 gacatcaggg tcactcagca attctcctag ttcttcataa cggtcttcta cagcttgtag
     9841 ttgatcatag atgttcattt ttcttcattc tccttattga tttcaggggc aaaataatgt
     9901 ttacggcaaa ccgagatata ggtttcatta ccaccaattt ggatctgttc tccatcgtaa
     9961 acgggcagtc catcctgtgt tcgcaacacc atggtcgcct ttttcttgca atactgacag
    10021 atggtcttga tttcgtcaat cttgtctgct aaaagcaaga gatatttgga accttcgaac
    10081 aattcattgc gaaagtcatt tttcaagcca aaagccatga cgggtatgtc taactcgtcc
    10141 acaacacgag ctaggtcata aacatggtgg cgtttgagaa actgggcttc atcgaccaac
    10201 acacagtaag gtttttctgg taggcctcgg atatagccaa agatatccgt tgtttcctca
    10261 atcgcaaggg cagggcgttt catgccaatt cgactcgaca catagccaac accgtcacgc
    10321 gtatccagag ctgaagtcat aatcacaaca ccttttcctt gctcctcata gttataggcc
    10381 accttgagaa tctcgattgt ctttccagag ttcatggtcc cataacgata atacaactgt
    10441 gccatgtttc ttgcttcacg tccatttcta aatttttgct acattctagt atatcataat
    10501 tttcttaagc tttaaacggc aaaatgtggt aaaatggaag aaatcaaaac tagtggagga
    10561 agctattatg ccatttgtac gcatcgattt atttgaagga cgcacgctcg agcaaaagaa
    10621 agctcttgct aaggaagtaa cggaagcagt tgtccgcaac actggagccc ctcaatctgc
    10681 tgtccatgtc atcatcaacg acatgccaga aggaacttac ttcccacaag gggaaatgcg
    10741 tactaaataa gctagcttaa gcagaattgc ttaggctttt tcaatctcca agtagcattc
    10801 attgaagaaa tatcctaaat ttgttacaat ttgaaaagaa acttggagaa tttccaagaa
    10861 aagagctatt aattaaagga aacattatga ttacacgtga atttgatacc atcgctgcta
    10921 tctctactcc actaggtgaa ggggctattg gtattgtccg cctgagcgga acagacagtt
    10981 ttgctattgc gcaaaagatt tttaaaggaa aagacttgaa caaggttgcc agccacactc
    11041 tcaactacgg tcacattatt gatcctctga ctggtaaagt catggacgag gttatggttg
    11101 gggctatgaa gtctccaaag accttcactc gtgaggatat tatcgagatt aacacccacg
    11161 gtggtattgc ggtgaccaat gagattctcc agctagctat ccgtgaagga gctcggttgg
    11221 cagaacctgg tgaatttacc aaacgtgcct ttttaaacgg tcgcgtagat ttgacacagg
    11281 ccgaggcggt gatggatatc atccgcgcca agacagacaa ggccatgaac atcgcggtca
    11341 aacaacttga tggttccctt tctgatctta tcaataatat ccgtcaagaa atccttaaca
    11401 cacttgccca agttgaggtc aatatcgact atcctgagta tgacgatgtt gaggaagcca
    11461 ctactgctgt tgtccgagag aagacaatgg agtttgagca attactaacc aagctcctta
    11521 ggacagcacg tcgtggtaaa atccttcgtg aaggaatttc aacggctatc attggacgtc
    11581 ccaacgttgg gaaatcaagc cttctcaaca acctcttgcg tgaggacaag gctatcgtaa
    11641 ccgatatcgc tgggacaaca cgagatgtca tcgaagagta cgtcaacatc aatggtgtac
    11701 ctctcaaatt gattgataca gctggtattc gtgaaacgga tgatatagtg gaacaaatcg
    11761 gtgttgagcg ttcgaaaaaa gccctcaagg aagccaactt ggttctacta gtgctaaatg
    11821 ccagtgaacc actgactgcg caagacagac aacttcttga aattagccaa gataccaatc
    11881 gcattattct acttaataaa accgacctgc cagaaacgat tgaaacttcg aaactacctg
    11941 aagacgttat ccgtatttca gtccttaaaa accaaaacat cgacaagatt gaagagcgaa
    12001 tcaacaacct cttctttgaa aatgctggct tgattgagca agatgctact tacttgtcaa
    12061 acgcccgtca catttccctg attgaaaaag cagttgaaag cctacaagcc gttaatcaag
    12121 gtcttgagct ggggatgcca gttgatttgc ttcaagttga cttgactcgt acttgggaaa
    12181 tcctcggaga aatcactggg gatgctgctc cagatgaact catcacccaa ctctttagcc
    12241 aattctgttt aggaaaataa gaaaaatcca tgatccttca ttcggtcatg gattttattg
    12301 tctttattag taatctggtc ttaagacccc tgttacagtt gccttagttg cttcgtagtc
    12361 gccatctacg acaaccttga taatgcgttt ggcatcttct tctggtgctg gaacaagagg
    12421 tagacgagtg ggtccagctt caaatcccat atagttaaga attgccttaa ctggagcagg
    12481 acttggataa gagaagagag cattaacctt aggaatgaat ttacgctgaa ttgctgcggc
    12541 tttcttcata tcgctttctg caatggcagt aaacatctcg tgcatttcat ccccatttgt
    12601 atgagaggca acagaaataa ccccatccgc cccaaggttc atggcatgga aagcatctcc
    12661 atcctcacct gtataaatca agaactcttc aggcttgtgc tcaatcaagt aagccatatt
    12721 agccaagcta gtacattctt tgacaccgat aatatttgga tggtcagcca agcgaagcat
    12781 ggtttctgga gtcaattcga caactacacg ccctggaatg ttatagataa taattggtag
    12841 gtcagaagca tctgcaatag tcttaaagtg ctgatacatc ccttcttgag aaggtttgtt
    12901 gtagtaagga acaatagcaa gcccagctgc gaaaccacca aattccgcta cttctttgac
    12961 aaactcaata gagtcacgcg tatcattagt acctacaccc gcaatcaaag gaacgcgtcc
    13021 attgacaacc ttttgtacag ccgcaaacaa ctccaactcc tcatcgtggg tcaaagttgg
    13081 actctcagca gtcgttcctg cgagaagaat tccatccgta tgatgggcca ataaatgctc
    13141 aatcaaggct ggaatagcat caaagttaat agaaccatcc tcatgaaagg gggtaataaa
    13201 ggctgtaatg attttacatt cttttaaatc ttgataagac atgaaaacac ctctctattt
    13261 caaagaagga gttcatctga actcctaaac gatatgacta ttttaattca aatttcaatt
    13321 cggctgttgg acgaaccaat ccacgttcat gaagagtttc agcaatctga actgagttcc
    13381 aagcagcacc tttgagaagg ttatctgaaa caacccacat gtgaattcct ttttctgcat
    13441 ccaagtcttt acggatacga ccaacaaagg tatcacgcga accaactgca ttgatagctt
    13501 gaggatagat ttgatgagct acatcatctt caagaacagc acctgggaag gctgcgatag
    13561 ctgcttttac ttcttcgatt ggagccactt cttttgtttc gatataaaca gactcagagt
    13621 gagctgacaa gactggaata cgcacacatg ttgcagatac tgcaatgcta tcatcttcca
    13681 taattttctt agtttccttg gtcatcttca tctcttcgta cgtgtaatca ttatcagtga
    13741 aaacatcaat ttgtggaaga gcgttaaagg cgataggata atgtttcttg tcaccacctg
    13801 aaggcaaaat ttccgcatgc aaatcacatg gtttcacacc atcattcaag acttcacgaa
    13861 gttcacgttg tgtctcaaga attgctccca taccagcacc tgaaacggct tgataagttg
    13921 aaacaatgat acggtccaag ccccattttt ggcgaaccgg ctcaagagcc accatcattt
    13981 ggattgttga acaattaggg caggcaatga ttccgttgtg ggcatcaagt gcatgagcat
    14041 tgacctctgg aacaaccaaa ggaacatctg gattttgacg gaaataagat gtattatcca
    14101 ctactaccac gccagctttt actgcgtatg gtgcatactt agctgatgta gaactacctg
    14161 ctgaaaagag agcaatatca actccttcaa aagctgtttc agtcgtttct tcaattgtaa
    14221 tatcttgatc tttaaatttc aatgacttac ctgctgaacg tgcagaagca aggtaacgga
    14281 ttttatcgat tggaagtgtt gattcttcca acatttttat catctgagca ccgacagcac
    14341 ctgtcgcgcc gactacagca actgtatatc ccataaataa cctctttcgg aattttctaa
    14401 aaatttctat aatagaagta ttatactact ttttccatga attgcaaagc tttttcatca
    14461 ttttttggaa aataaaaatc ccagtcgcta gactagggac taagaggcat cttcatgtga
    14521 tgagcaggtt cacacaactc atcaaggtcc gctcctgcgt tatgacctcc ttatgctcaa
    14581 tagtagtccg aagactacct atcgactcat cgcatattct atattactag agatacttga
    14641 ttttgtcaat aagaaatttt ttcgatcgag tataacaaaa aactctcgta ttcaagagtt
    14701 tccctataca tatcatgcta attgccggga tcgaaccggc gacctcatcc ttaccatgga
    14761 tgcgctctgc caactgagct aaatcagctt acttaagaag tatactatat tcagaaaaac
    14821 ttgtcaagtt tccttagaaa ttttccatag gaaaaagcca ggtaagaact acctagctta
    14881 tcttcttcta tttacttaaa tcaattcgac gaccaatttt accaataata atcgccccaa
    14941 taatcaatga agcaaattca ccgattcctg ttgtaaacca agtaaggaag aatggtaatt
    15001 ctgctacaat atttaactct gcagcgatag taaacatgga aattgaaaag aggattgaaa
    15061 agaagaaatg atcttttcga atcaatccgt taaagaggta atccttgcta tattttgcaa
    15121 aaagccaaac acctaaactg aggaatacta aggttgaacc accaccaaca aagacatcta
    15181 gcagtccgaa gctaaagaaa ttagcaatca tacaaccgat ggtaactccg atgatgtact
    15241 taggattgta aaaagccata aagttcatca tttctgaaat acgaaactga taagcaccat
    15301 agctgatggc atttaggggc ggtgtgacag tcaaaacgac gtagatagca gcgacgattg
    15361 caatatctgc aatatcacga atagttaatt ttttcatctt ttctcctttg gcggttgccc
    15421 gcgtgtaata tgcttggtga aagaagctaa gcaccaaggg ttgctttatt caaccctact
    15481 agtatagcac aatagcctgc tttatgctat acttaacaca tgaaaattcc tattcaaaaa
    15541 ttttttaaca atgaaatctt agcctatctc ttttttggcc ttgcgacaac tctagtttcg
    15601 attctctcac gactagtcat ttatcaacta agtcatcagg aactcctggc tactgcccta
    15661 gcaaatatta tcggtatcct atttgccttt atcacaaatg atacgattgt atttaagcaa
    15721 aaaaagaaaa atagacttat ccgtttagtg aaattttctc ttgctcgcct ttctactttt
    15781 ctgttagact tgtttttaac ttttctcttt gtaacccaat ttcctcacat tatagggcaa
    15841 ttcgtaactg aaaacattga taagataaat gctattgaaa caataattgc acaaatattc
    15901 attattatca tcaattatat attgagcaag gcctatattt ttagaaaata atgctccatt
    15961 tatgagcctt ttaattgcct tctataatga tttaggatac aatgaaacac gaaacattga
    16021 aaggaaaaca gtatgttaaa aaatctaaaa tcgttcttgc ttcgaggaaa tgttattgac
    16081 cttgctgtcg gtgttgtaat tgcctctgct tttggtgcta tcgttacttc acttgtaaac
    16141 gacattatca ctcctcttat tttaaatccc gctttgaaag ctgctaaagt tgaacgtatc
    16201 gctcaacttt cttggcatgg agtcggctat ggtaacttct taagtgctat tatcaatttt
    16261 atctttgtgg gtaccgccct cttctttatt atcaagggca ttgaaaaagc acagaaactg
    16321 actggcataa agaaagaaaa aactgccgaa aaaaaaccaa ccgaattgga agtccttcaa
    16381 gaaataaaag ctctccttga gaaaaaataa tcgattaaaa ggatctagcg caaagctaaa
    16441 tccttttttc tttactcttt gggtaacttg cctgcttttt caagcatttt tttgatcaga
    16501 taaggcatct taacattctc ccgccctttt ttctcaatca gttttttcac aaattctggc
    16561 atttgtaaat cttcagattc agctaaaatg tttttcgtct cgtctgaagg aactaactca
    16621 tcaaaggtct cttcttctgg gagaaattcc ttaaactctt gattttcatt gactctaact
    16681 gtattgacca aagcatcaat caaacgagaa tctgtatttg gcattggtgg acgatggtag
    16741 tttaccccaa attcctggca taagtcataa cattctacat cattgtcaaa caagacctca
    16801 atatgctcac tgatgaaact aataggtaca aaaatataat ggtctggatg ttctgtctgt
    16861 tctctgagat actccaaaac atctggttta atccatggaa taccaatatc actctcactc
    16921 tgccaagtgt tggtatattg ttctgaactc aagcccagtt tttcagcgac tagcttgcta
    16981 ttttcgaaaa tttggtctat ataaggatca ccaaagtcca aggcaaaaat gggcacacta
    17041 tgggctgaaa agatgacttt aaagctgtct tgctttactt cttcttttaa aatcttagca
    17101 atttcatctg cccaatagtt taagagcact tcttcctgat accagtcctt aatgaccaaa
    17161 aattgaattt gtttgctttc taaaaatttt tcatagccca tgacagagta gaaagaataa
    17221 tggggctcca aaatcaagca gatacattct tcaacaccat cagtttccat ctgcttgatc
    17281 acgtctggaa taaagggacg agaaaatttg ttggcaaagt agataccgta ctcctcccct
    17341 aaacgttctt tgactaaatt gacctcctca cgtgtaatcc gctgcaaagg cgtcccaccg
    17401 atacgaatat agttgtcata gagagtctgg atttcgtggt cttggggtct aactccacga
    17461 cgaatgtttg taaagaattc tgctactcct tcaaaactaa tctcctctgg agatccaaag
    17521 gtcatcatta atatggcttt tttcatgtta tcatccttat gatattattt tctctatcca
    17581 ttctatcatg aaagaaaaaa atagtaaacg tttcctacgt ctactatttc ttttgctctt
    17641 ttgttttttt atctcgtctt ataattagga tgataaggac aagaagtaag aggacgataa
    17701 taaggagtag aaaggctaga atgtaaatcc aatgactggg aattccgtga tcgaaatacc
    17761 gtgttcctac tgcttcccca ctttcatcct gtgctacttt caccggtgca tccgttattt
    17821 tagctaaaag gatatgtcgt ccattagtta tgttaaggaa acatctcgct tgtacttggc
    17881 tttacttagc agatattgat agtaagcctg gtgttcctca tccttggaac tcaaggttcg
    17941 ataaatctcc gtgtcatagg catccacttc taaaatccca aaaatttcaa gaccacgttc
    18001 tcgaccattg tagtagatag aaccgtagcg atgctggtcg aagaattcct tatcagcaaa
    18061 tttcttaatc tcaccgaaca tagcccctga agccatagag tgtccgtaga tgatcgtatt
    18121 aaaatcagta aagttgggat taaagcgata gtcgagaaaa attgatccca ttatcgtata
    18181 atcgccaaag gcattgcggt caaggtattt gacattatcc tgactttgta gaagcggata
    18241 gtctaccttg gtcccatcaa ggctaatcca accgcaaaca tctttgttca agtgctgtag
    18301 ggtttcaaaa cctgtgctcg aagcatcctt ttcaatagga ttatagtgat catagtcact
    18361 tgcttctact actctctgcc aactaaaaag agctacaaaa acacagaaga ataccagaaa
    18421 tacgttttta aatcgcgctc ttttttgaac cgtcatcagc actcctttct atgcgagatt
    18481 tcttaaaagg aaaggaggcg ggacaaaacc gcctcttttc tattcaccct tagtcagtaa
    18541 aagggtctgc ttcttgcatt ttttttactc tctcttctac gacgtaggat caagtagagg
    18601 acaaggagta agaaaatcaa gagcaagaac aatacaaaca agataaggta ccaaatccat
    18661 agtgggattg atgagaggaa acgtccaaga gacgagtcat caaagacact gtatggaaat
    18721 ggttttgatt tttttgtatg gaaagtattt ttagggacgg tgtctgtaat ctttgcgact
    18781 acgatatgac gaccattggt cacatcgaga aaacaggtac tgagtaggat gatacgatca
    18841 ctcggtgaga gtgagatatc ccgcttgtgc atggcgactg agagcaggtg gtctagatag
    18901 gcctgctggc ggtcctcacc ctgtattcct ggatcataga tgttaaagtc ataggcatca
    18961 acctccaaca tctcaaagat ctcgagccct ttttccacac cattgtagta tatactaccg
    19021 taacgatgct ggtcaaaaaa ttcctgatca gcaaacttag ccacatcacc aaacatgacc
    19081 ccattttcta cgtggtgccc gtagataatg gtattaaagt cttcgaactt aggattattt
    19141 cgtgcatcga gaaagatagc gcctgtcgct gcaaactcac ctttggagtc cttgttgaga
    19201 tacttttcat tgtccttggc ttggactaag ggatagtcga tattggtgcc atagacattg
    19261 atccaaccga ggacttcggg attgagttct tggagtttgc tgaagcctga aaaactggcc
    19321 agctcatcct gttgcgtcgt gacaggtcga taagcttcgt actcacttga cgaagctaag
    19381 gagtagactt ggttggaatc ccaaagggcg tagaaaccaa agagaaagat caaagctgca
    19441 aaaatgagca gcaagtgatt gatcacccca tccacagcaa gaacgagacg cctagacaga
    19501 ctcttttttg gtttctcacg cttggttttc atcatctgcc cccagccgtt taggcttctc
    19561 tacgtttttt agacaagaca acaaatccag ccaaaccaag accaatcatc aaaatgaatg
    19621 gaaggttatc aatcaagaga ccagtaggag taacgtcgtc gattttgtta gtaactttgt
    19681 tgtcgttttt cttttcacct atgaggatat ctgttaatgt aaaatctaca tttttttgtc
    19741 cttgagatgt ttgttctgca ccatttgtag tataaattga tgaatctgta taacctgcta
    19801 ctccagtttc agttactgta tatttagaac ctgctggtag ttgttcaact gtaaatgttt
    19861 caccatcttt aagagtaaaa ttgtactcaa ctgtatctgc tggggtcact actgccaaca
    19921 cctctgactt agatccatgt tttactataa tattcgtaac aggggtttct gctgttttat
    19981 ttgtacttgg aagttgaatc ttgatatgga attggaaatc tcttgtttta tcccctgaag
    20041 ctccatcaac ttttttagta attgttaatg ctttcgcatt ggggtctact tgactcggat
    20101 catcaggatt aggctcctta cttgcgtctt tggtatatgt gttatcaaat aaattataaa
    20161 cgccttgttc acttggttct actttagggg cgttagattt attattttcc ttaaagtata
    20221 ctgatgaaat atagacacca ccatttactt tattcttaac aataacgtgc atttcatatg
    20281 tacgtttgtc gtatctcatg gcatcaattg ttttaccatt tttggtaatc gcctgccatc
    20341 cagtttttgc ttccgctaca tcataaacgt attcaccagc atggccataa gcaactcccg
    20401 aaaaaatgtc ttctgttgct ttttgaatct tatcagcagt tgggtgatca tttttattgt
    20461 attctacatt tctatctgga attgcaactc cggtttgata tggcgcaccg ttagaagatt
    20521 gtcctgtttt ttctgtaaac ttaaatgtaa atgtcgctgt tggtgttgtt attccctctg
    20581 caatattcaa cgttttatta atcttcacaa cagcattatt ttcaccattt gctttggtta
    20641 ttgctgaatt atcatccgca aaagtcggga cacctctgaa tacggacaaa gcggttatag
    20701 ctgcaatgct tgcagtgaat agctttttaa agaatgtttt tttcatgatt atttcttttg
    20761 tttttttatt ttcttttttc attatgatca tcaaaagcct cgtcttctaa tgactgttac
    20821 aactttgcct tgagtatcct gtatagggat ggttccaaaa gcacgactgt ctacagccgt
    20881 tgttcgattg tccccgagga caaaaagttg tcctgctggg actttcatcg ggaaggttgc
    20941 cccttcctta tagagcagcg tttctttgta gatatcttgc tcttgttgag gagaaccgtt
    21001 gatgatgaga ccattttcgt ttatatcgat tgtacttcct tcggttgcta tgacacgcgc
    21061 cactctttcc ttacctttat aactatagac tagcaaatca ccaatcgaat agcgtttatc
    21121 caacctataa tagacgacca agtcgccatc ttttaaggcg ggcttcatgc catcgtcatt
    21181 gtatcttaat aatccaaaga cgaaaaagta aaggatggct agtacaaatc caaccatcag
    21241 aagtttactg actaagtaaa ggatatctcc ccagacactc ggcggagact tatcccgatt
    21301 gacttgtgtt actggtttct tatgtttctt tttaagcagc atcacttcct cctattcacc
    21361 acaaggtgac caagtaagat gataaagaag atccctccta gaggaagaac gactccaagc
    21421 acgagagtgc tactcaagaa gtcaattccc gtttcaggta cgctgttttt attattcgtg
    21481 actgtcgcag acttatttgc atcaagagtt ccttcttttt tatcatagga cacctgatac
    21541 ccacgagacg aacttgcttc ttcttcgata ctataacgag catttagagg aaggtcgaga
    21601 atcttgatgg ttttatcttt ctttagatca actgtcgcct taccattggt gaattgtagc
    21661 gttgtttttt gattatttac tattgcacta tacgatccat tcaatggttt attttgcgca
    21721 tcctttacgt taatggtaat cttaaaggat tgcagaagat tagcaaaagc acctgtaact
    21781 ttttttgtga ctgaaagtgt cggaagtctg tggttggtga cgattgtttg aacatcctct
    21841 gacaaagtcc cctcttgttt ttcataggtg acatgatatc ccgttctaga gttctctact
    21901 tcttccacct tatagtgggt atcacgaggc agataactga gggcagtttc ctgactattt
    21961 ttgagagaaa tctgtgcttt cccgttagtc actgttgtat tcccaaactt gccgttaatc
    22021 ggcttgccat ccttatctga aaaggtaaca ttaattgtga aagatttatt aggtgattgt
    22081 tcaccttcta ggattttctt tacggtgaga cttggaagct gtcggtaaat aactttgaag
    22141 gatggtttct ctttcgtacc tgtcttttga acttcgactg tgtatcccgg agcgtctggt
    22201 gctttcagtt cgtagtcata tcccttagct acctttgcaa aactagtatt ttcagtaaaa
    22261 ctattcgttt gaactggact agtgaccttt cgataggaat cctttatact tccatctttc
    22321 ttttggttta agtttaattc gacactaggt ggacgatttg ctgatggatt tgattttcca
    22381 tccacacctt tccactcaat ctctacagga accgtcaatg gatctgacgg cttgaaagtg
    22441 ggcttctcag aatagtcttt tattttggta cgtgaggtcc caataccata ggaataggca
    22501 acttttgccc ccttgttgga gtagagttta gtagcatcgg cttcttcggc atcatcacta
    22561 gtaagtgtct tatcacccgc aatcgcatca aatgcctctt ggctagaggt gacagtaaac
    22621 ttgagaacgt acttggcgtc atcctccaaa gtgtaactcg gattaaactt ggctgttact
    22681 tccactaatc cctgttcgtt cttcttagtt tcaatcgtaa cttgattgtc attcagttct
    22741 tgctcgttac catccttgat tttgacgaca cgaaggtgtg aagcatcacc aggtaacagc
    22801 tgcacgtact tggacaagac atctgatata gttacatggt gtacgcctag aggtagaatt
    22861 ttatctgtga tttctttgaa tttttgttgc aagtcatttt cattattggc agaaaatatt
    22921 tcgttgggga ttccagaatt ataaccactg atatatcctt taagagatgt gatactatcg
    22981 tttgaaccta tataatatct gaatttgatt gaataaaagc catctatttt tggagctatt
    23041 aaactagata tattcagcat tcctctttct aaaccagagg taaaccaata tggagtatca
    23101 atcatacgtc ccacatttgg attagaataa tagttatata ttgttctccc actattagac
    23161 tcgtaataca tattagcttc gccatctgac agcagaataa ctactttttt tgccccagcc
    23221 cttgcacttt gcaacaatct ttgagcttca gttaacccag catttatatt tgtcccagtg
    23281 ccaatgcccg cgtccatacc ataagaacga ctagagtcag caattgttaa cgaactaaca
    23341 atattttttg agctattaga atccgtgctc caagatacta aagttttagc atcatcatat
    23401 gaagagatat ttgaatacca accagctcaa tttggccaag ttccatattg ataactcaga
    23461 taatattcat tataataacg gtcattatac tgattatcaa tctttccggc aaaaccaact
    23521 atagacagac ggttttggga attagaaaga attgtatcaa tgagcccctg acgaccattc
    23581 acacctttca gtgtatgttt tagtgcttca atcctactaa tgtatcgtct actagagtaa
    23641 gaccacacat ctcgctcttc catactccct gaaagatcgg caaccaagac tacatccaag
    23701 ggttctgact gggtctccgt tcccagttta gatgtgatat ccagtgacaa ctcatactgg
    23761 tctttttgcc ctgatatcgg agtaatcgtt ttgtgcagag ttgtctgagg ttcagttatt
    23821 gaatctgcac gtaaagaatt aattggtgca cacaaaaaaa gaatagcgag aaagataact
    23881 aaactactgg taaaatattg aatcttctta aaatcatatt gaacgttcat gctatctccc
    23941 ttgctagaat atgttttaat ctgatactat ataaatctga gacttccata agataattgt
    24001 ataataatat taacttcgtg tcaattaatg tgtttgaaaa catgttatta taaattacaa
    24061 aaaagtatga ttcttctttg tttttcaact ttttctgtgg taaaatggaa aaaatagtaa
    24121 aaaatttcat aaaataaaga tgcatatatt tattctaatc gctcgaaaat ttcttttgaa
    24181 agtcttctga atttgaatta ttatattttt tcaaaattca taaaatttct caaatcatat
    24241 ttttccgaag ttttgtattc tattttatga taaaaaagga gtttttttat gacttatcca
    24301 aatctcttgg accgcttctt aacctacgtt aaggtcaaca cgcgctctga tgaacactct
    24361 actactactc caagtacaca gagtcaggtt gacttcgcaa caaatgtcct aattcctgaa
    24421 atgaaacgtg ttggactgca aaatgtttac tatctaccga atggttttgc tattggaacc
    24481 ttgccagcca acgatccgtc tttaacacgt aagattggtt ttatatcgca catggatact
    24541 gctgatttta atgctgaagg agtcaatcca caggtaattg aaaactacga tggtggtgtg
    24601 attgaactag ggaattctgg tttcaaactc gatccagccg acttcaagag tcttgaaaaa
    24661 tatccaagac aaacactcat cacaacagat ggaacaacct tgctaggtgc tgatgacaag
    24721 tcaggaattg ctgaaattat gacagccatt gaatatctaa ctgctcatcc tgaaattaag
    24781 cactgtgaga ttcgtgttgg ttttggtcca gatgaagaaa tcggtgttgg tgccaataaa
    24841 tttgatgcag aagattttga tgtggatttt gcctacactg ttgatggtgg tccactaggt
    24901 gaacttcagt acgagacttt ctcagccgct ggtgctgaat tgcatttcca aggccgtaat
    24961 gtccaccctg gtactgccaa agggcagatg gtcaatgccc ttcagctagc aattgatttt
    25021 cataatcaac ttccagaaaa tgaccgacct gagttaactg aaggttacca aggtttttac
    25081 catctaatgg atgtgacagg tagtgttgag gaggtgcgtg caagctacat cattcgtgat
    25141 tttgaaaaag atgcctttga agcgcgtaaa gcatccatgc aatctatcgc tgataagatg
    25201 aatgaagaac ttgggagcga ccgtgtcact ctcaacttga cagaccagta ctacaatatg
    25261 aaagaagtca ttgaaaaaga tatgactcca attaccattg ctaaagccgt tatggaagat
    25321 ctaggtatca cgcctattat cgaaccaatc cggggtggaa cagacggctc taagatttcc
    25381 tttatgggaa tcccaactcc gaatatcttt gcaggtggcg aaaatatgca cggacgtttt
    25441 gaatacgtta gccttcagac tatggaacgt gcagttgata ccatcattgg catcgtagct
    25501 tataaaggct aaaaagacga ggtggctcag ctacttcgcc tttcttttta ttctactggt
    25561 ttttcttgat ttccagtagt tgtagaagat tctgttgttt cattttctga agttgattca
    25621 gcaggtttag aatctcttgt attgcttggt ttgttttcgt cgctagcagt ttcaatgtta
    25681 gattctgcag ttgcgtttgg ttggttctca gcactggtgt tatcactatt tgcttcagca
    25741 tttcttgctg gacttgtttc ttcacttgcg ctaacttttg actggatttg atgattcaaa
    25801 actagaatag cttttgtcga ttcaagtaaa gctgttttgt ctttactatt agcagaaagt
    25861 tgatctaata atgcatccac cttatcaaag tccgcatcag atccattatt actttctaaa
    25921 taagagtgaa gcgacatgag aatatcgtag agtttttgat agagtacaag tgtctgagaa
    25981 tcttgctcag cattttcctt ttcttgttga agggcgctag cgatacgagt caaaacatct
    26041 tttacctgac tgtttacttc atccaagtct gcatcagcct tgtttgtggc agcttttaga
    26101 ttttctactt cttctgccaa ggattgtctg attccttctt catggatttg ttccaagagt
    26161 tgatttgcct tgttcaaaag actttctact tcttccttgc tatctgtcgc agattattgg
    26221 ttgctatcta ccatgtactc ctaaaacagg agagttataa tccaagatta caaggcctta
    26281 cagaaataag aaatccagat aagacaatgt tcgtccaaga cgctattcgc ttcgcacagc
    26341 agcacggatt caatatgctt taattttaaa gtttaggtgt caagacctct ttttagtgtg
    26401 cccaaaattt agagaagtaa tcaatcaact aacttttatt tttttcaaac tttcagtaaa
    26461 ctgacctaaa gctaactcaa tctgtctttg tagatgcttc tgctatcagc tagaagttga
    26521 tctacttttg ccaagactgc cttctcatca aaagttccag gttgatagtt ggattgcagg
    26581 gatggaatct tgtttttcaa agccgcttca tatcccttag tttgaacctt gatgtagtga
    26641 ttgtggtcgc catgaggaat cacaaaacct tctgaatctt cacttataat tcgattggca
    26701 tcaaaaacca taaccatctt cttcctcatg gtggacatgt agtgacggat tacttaatac
    26761 agaactagaa gaacttccta cctcttccgt gttagagtgt gatgggggat tgttaagaga
    26821 tgacttagga atatagtgat agtgttcccc atgtcttact atataagcat cacctatatc
    26881 tctgacaata tcattagggt taaagacata tgtggctgct aattcacctg ccgacaagtc
    26941 actctcagga atgaaatgat agtgaccacc atgtggtact attagtagat tgaaatagaa
    27001 tatgagcaaa ttgataaggg gattttaaag taatttctaa caatgattta gaaactatga
    27061 tgtgctattc taaattcaac tcactatata taaccatcat cggtagtata acgtccctgt
    27121 aattttgcta cagatacttc tgcactagct cctttatcgt ctttaccatg ttcttgtttt
    27181 tggcgattga tttcatcttt tgttcgtaca ttttctgcat gagcttgatc tttaaggtaa
    27241 acataatact ttccatctac cttaataata tatcctccct taacctaact gacaatatct
    27301 tgatctttcg gctgatagtt gggggctttc attaatggct cttcactaaa gagcgcatca
    27361 aaaggaactt taccattata gtagtgataa tgatcgccat gagaagttac ataaccttga
    27421 tctgtaatct taataacaat ttgttttgct tgaattcctt ctttttgact aacctagtct
    27481 ggagtcaaat tttcagtctt cttagtgtct ttattactgt ttacatatga aacacgattt
    27541 ttatctgtat tggcctgtta gctatgttgg ttcagagcat aaacacacag acttaaggaa
    27601 aggataacaa cagatccagc tgctatatat ttctttttaa atttcataat tacctcattt
    27661 ctataattat ttatatgatg tcttcattat taaatgatta tagaaattaa ttaaccaatt
    27721 aattaactag taaatattcc acctcttttt aagttgtatg tcaagaaatt ttatatatta
    27781 ataataaaat gaaattctcc caaagtcaga gttttatttc taacttttga gagaacttca
    27841 tttttgattc agactttttc tactgctatt ccttacgcta tgagatcaga taaattcttt
    27901 tttatcactt ctccacttgg caatcttaat tcaatcgttc catccatatt gaatataaca
    27961 ctatctaagc ctaatccgta actagctgta aatttttcta atttttcttg tacaggatct
    28021 actgctggag cttcctctaa tgctggatct aacatagggt cactccccac attcccttct
    28081 ggattcaaca ttccattatc cgttgagttt tctggtttta caggtttttc gtttggtgcc
    28141 tctggtaaag aatctgctgg tttattttct gttggttggt tctcaactgt tccagtagat
    28201 acttttccat tttcagatgg tttattttca ccatttcctt gaggtgcttc tcctgtaaaa
    28261 tctgccatat tctttttaat gacttctccc gatggtaaat ataattcaat tgttccgtcc
    28321 atattaaaca agacattttc tagcttcatc ccataacttt cagcaaattt tgctactttt
    28381 tcttgtacag gatccactgt aggaacttct tctaacgttg aattactagt actattccca
    28441 gtttcagaaa gtttttcttt ttctaccttc tcactagtct ttggttcttc taccttttca
    28501 tcaagttttg agttttcttg tgctttattc cttttaaatt gtggtagaat acttggttta
    28561 tcagtttgat tttctttttc caagataggt acttccacaa tataagtcga ttgattgtcc
    28621 aaataagcat ttgccatgaa ggttacagga attttatttc cggccgttct ggttgttcct
    28681 tggtttaatt tcggaatcgg taatttgatt tcaccaactt tatagttatt ttctaaataa
    28741 gcatttccat gaaattcatc aaacactctg actaaagcat cagttccttt aggcactgca
    28801 aattgagggt tcactcttaa ataagtatcc cctgcatgga aaggatagaa aatcgtttga
    28861 ctggccattt tgtaagctaa agaggttgga actgtaaatg taccatcata acttacttct
    28921 ggataatctt ttgaagcgat agtatactta aatgtttgtc ctggtaaata aggttgatct
    28981 aattcaaagt ttgcaatatt ccctactcct tctccaaata ctttaccaga tactttctcc
    29041 aatacttttc catctggtgt tattaatttt actagcatat tgatacctaa ttttttctcc
    29101 aattcaggcg gaaaactaaa agaaacgcgt ttttgaccat tggctagagt aaagttttga
    29161 ttattaaacg tactattttt taacaaatta acaacattcg ttaattcttc tccagtataa
    29221 actttattcc cttctttttt agcaactcct tcttcgggtt taaacagttc atagttactg
    29281 tgagaatgac caattccaac cggtttatgt tcatcaatcg gatctgcatg atggtgatct
    29341 ccatgcggat aaataatcgc atttttttct ttattcacga caatactttc acgtttgaca
    29401 ccatattgtt tcataatgcc agcaattttt tcttcgattt ttttatctaa atctttcatt
    29461 tctttggcat tacttggata atcctgttca tgagatgaca aagaatctaa tccattatga
    29521 ctagttttaa cttcctctaa atgtttttgc gcagccttaa tttgctcttc tgtcaagtcc
    29581 ttcttgaaga aataatgatt gtggtctccg tgactcatga caaaacctga ttcatcttca
    29641 gcgataatac gattagcatc aaatccgtat ccatcttctt catgtttctc atgtgaagtt
    29701 cctggattga ttggaagaga tggagaaggt gttgctagac tattgtttgg aagagtcggt
    29761 tgcccaattt gatttgattt tggaatgtaa tggaaatgat caccatgtct tacaatataa
    29821 gctgtagccg tttcttcaac gatatctttt ggattaaaaa tataaccatc agatgctgaa
    29881 gagagctcct tacttgtcgt taaagaagaa ggattgcttg aaagactgcc tagactagac
    29941 actacttcat taggttttgc atttgtagaa actgtagaac cagttccact gataggcacc
    30001 attctggcaa tcttttcttc taaggcagaa agcttgctgt aaggaataaa gtggtaatgg
    30061 tcgccatgcg gaatcgcaac tccatttggt gtacgactga taatcttagc agggtcaaag
    30121 accaggccat ctgattcact gtaacgttgg gcgctaggtg aatcatagag ttccttcaaa
    30181 agactctgga gattttcaga tttatttgct ggcttgctag ttgatccttt tgctacagat
    30241 tgcgtgttat tgtcactagc tgttgaagaa tagcttaact gactcggttg catatttttt
    30301 ccagccagat gtgctttagc tgctgctaat tcactagcag ataaatcgct tttgggaatg
    30361 tagtgatagt gacctccatg aggaacgata taagcattac ccgtatcttc gataatatca
    30421 gctggattaa agacataacc atcatttgtc gtatatcgtc cctgagacct tgctacagca
    30481 acattagagt taaccttctc attatctttg acatgttctt gtttttgacg attgatttca
    30541 tctttagttc gaacattatc agcatgagct gcatctttca ggtagacata atattttcca
    30601 tcgaccttga tgatataacc acccttgact tcattgacaa tatcagcgtc tttaagttga
    30661 tagtttggat ccttcatcaa gagttcttca ctaaagaggg catcataagg aactttccca
    30721 ttatagtaat gatagtggtc accgtgtgac gttacatagc cctgatctgt aattttgatt
    30781 acaatttgct cggcctgaat tccttctttc tggctaatct ggtctggtgt caagttttca
    30841 cttttctgac ttgactggct gccatctaca taagagacac gattattgtc cttattttcc
    30901 tgcgaacgat gctggtttag tgcataggca catagactca aggatacgat aacagctgat
    30961 ccagctgcta tatatttttt actgaatttc ataaatccct ca
//
LOCUS       DAVAZT010000023        30074 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVAZT010000023 DAVAZT010000000
VERSION     DAVAZT010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30074
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.023"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            51..1100
                     /locus_tag="VQT45_000980"
     CDS             51..1100
                     /locus_tag="VQT45_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HET2359318.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAVHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGSNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(1200..5042)
                     /gene="spuA"
                     /locus_tag="VQT45_000981"
     CDS             complement(1200..5042)
                     /gene="spuA"
                     /locus_tag="VQT45_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HET2359319.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPGNANASLEKTEEKPAASPA
                     DPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDD
                     VEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVE
                     KLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQW
                     PDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQ
                     IFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHL
                     GNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGK
                     LGADLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDST
                     NKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSDDSKIDDAHKVAKAAFVDP
                     AKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDY
                     LKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSD
                     PKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDLFEDLEPNYYHFMDADGTPR
                     TSFGGGRLGTTHHMTKRLLIDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARAL
                     NPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPA
                     FITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKA
                     ENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHL
                     LRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQS
                     TDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKARE
                     FNLGTAFAHLRNAEVLADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTS
                     HESTAEEKPDSTPSKPEHQNEASHPEHQDPAPEARPDSTKPDTKVADAENKPSQATAD
                     SQAEQPAQEAQASSVKEAVRNESVENSSKKNIPATPDRQAELPNTGIKNENKLLFAGI
                     SLLALLGLGFLLKNKKEN"
     gene            5459..5872
                     /gene="rpsL"
                     /locus_tag="VQT45_000982"
     CDS             5459..5872
                     /gene="rpsL"
                     /locus_tag="VQT45_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HET2359320.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            5892..6362
                     /gene="rpsG"
                     /locus_tag="VQT45_000983"
     CDS             5892..6362
                     /gene="rpsG"
                     /locus_tag="VQT45_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HET2359321.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            6787..8868
                     /gene="fusA"
                     /locus_tag="VQT45_000984"
     CDS             6787..8868
                     /gene="fusA"
                     /locus_tag="VQT45_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HET2359322.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEEIRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            8972..13363
                     /locus_tag="VQT45_000985"
     CDS             8972..13363
                     /locus_tag="VQT45_000985"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HET2359323.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPAFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFESVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            13465..13728
                     /locus_tag="VQT45_000986"
     CDS             13465..13728
                     /locus_tag="VQT45_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HET2359324.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            13721..13999
                     /locus_tag="VQT45_000987"
     CDS             13721..13999
                     /locus_tag="VQT45_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HET2359325.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            14020..14172
                     /locus_tag="VQT45_000988"
     CDS             14020..14172
                     /locus_tag="VQT45_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359326.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            14194..15435
                     /locus_tag="VQT45_000989"
     CDS             14194..15435
                     /locus_tag="VQT45_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HET2359327.1"
                     /translation="MVLPNFKENLGKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFKNAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            15445..15675
                     /locus_tag="VQT45_000990"
     CDS             15445..15675
                     /locus_tag="VQT45_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET2359328.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            15898..16620
                     /locus_tag="VQT45_000991"
     CDS             15898..16620
                     /locus_tag="VQT45_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET2359329.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            16837..18171
                     /gene="pepC"
                     /locus_tag="VQT45_000992"
     CDS             16837..18171
                     /gene="pepC"
                     /locus_tag="VQT45_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HET2359330.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALECRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(18227..19138)
                     /locus_tag="VQT45_000993"
     CDS             complement(18227..19138)
                     /locus_tag="VQT45_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2359331.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(19162..19965)
                     /locus_tag="VQT45_000994"
     CDS             complement(19162..19965)
                     /locus_tag="VQT45_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HET2359332.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(19993..20982)
                     /gene="manX"
                     /locus_tag="VQT45_000995"
     CDS             complement(19993..20982)
                     /gene="manX"
                     /locus_tag="VQT45_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HET2359333.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(21215..22234)
                     /gene="adhP"
                     /locus_tag="VQT45_000996"
     CDS             complement(21215..22234)
                     /gene="adhP"
                     /locus_tag="VQT45_000996"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HET2359334.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLTLAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(22573..23385)
                     /locus_tag="VQT45_000997"
     CDS             complement(22573..23385)
                     /locus_tag="VQT45_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2359335.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            23575..24993
                     /locus_tag="VQT45_000998"
     CDS             23575..24993
                     /locus_tag="VQT45_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HET2359336.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            25046..25753
                     /locus_tag="VQT45_000999"
     CDS             25046..25753
                     /locus_tag="VQT45_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2359337.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            25848..26822
                     /gene="folP"
                     /locus_tag="VQT45_001000"
     CDS             25848..26822
                     /gene="folP"
                     /locus_tag="VQT45_001000"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HET2359338.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSSLI
                     FPHFGFGQTFTEKELADFETLPIEDLMVAFFERALARAAEAGITPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            26824..28146
                     /locus_tag="VQT45_001001"
     CDS             26824..28146
                     /locus_tag="VQT45_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET2359339.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGIPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            28127..28681
                     /gene="folE"
                     /locus_tag="VQT45_001002"
     CDS             28127..28681
                     /gene="folE"
                     /locus_tag="VQT45_001002"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HET2359340.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            28724..29536
                     /gene="folK"
                     /locus_tag="VQT45_001003"
     CDS             28724..29536
                     /gene="folK"
                     /locus_tag="VQT45_001003"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HET2359341.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFEFYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIYILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPTLKQPIRNLYDALKK"
     gene            complement(29581..29898)
                     /locus_tag="VQT45_001004"
     CDS             complement(29581..29898)
                     /locus_tag="VQT45_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HET2359342.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMYGRETILLPEEN
                     DLF"
BASE COUNT         8527 a         5841 c         7006 g         8700 t
ORIGIN      
        1 ttagaataat ttttcaaatt gaaggacaga gatagacaag gagaatcaca atggtagaat
       61 tgggaatttc aacatttggg gaaataacgg agcttgaagg gactggacaa acttacagtc
      121 atgctgaacg cattcgccag ttggtggcag agattgagct ggctgacaag gttggtttgg
      181 acgtatatgg gattggcgag caccatcggg cggattttgc agtatcagcc ccagagattg
      241 tcctggccgc tggggcagtc aataccaaga aaatccgttt gaccagtgca gtcagcattc
      301 tgtcaagcat ggatccgatt cgtttgttcc aacagtatgc cactatcgat gctttgtcaa
      361 atggacgagc ggagattatg gctggaaggg gctctttcac ggaatctttc cctctgtttg
      421 gttatgactt gaaagactac gactctcttt ttgatgagaa attagacttg cttcagttag
      481 tcaatgaaaa gaccaagtta gactggcaag gtcgattgac tcaaacgatt gctggtaaag
      541 aagtttatcc tcgtccagtt caggacaaat tgcccttgtg gatagctaca ggtggtcatg
      601 tcgaatcaac agtgaagatt gctcaggctg gtctaccgat tgtatatgct attattggtg
      661 gtaatccacg ttattttaaa aagttgattc aggcttatcg tgagattgga agcgaagcgg
      721 tccatgctga caaagacttg aaagtgggag cccattcttg ggggtggatt gcggaagatg
      781 gtgagcaggc ggtgaaagat tatttccatc cgactaagca agtggtggat gctatttcca
      841 aagaccgtcc gcactggcag gaattgcgtt atgagcaata tttggagcag gtagggtcaa
      901 atggcgccat gtttgttggc aatccagatc aggtggccga aaaattgatt cgcatgatag
      961 aggatttagg attggaccgc ttcatgcttc atctaccgct tggttctatg cctcatgacc
     1021 aggttctgag agctattgaa ctcttcggaa cacaagttgc acccaaagta cgagcttatt
     1081 ttgctatgaa agaggcttaa taaaaaatcc taatcaagtt tattaggaca acaaatattg
     1141 tacgaaaatt aatcccccga gctataatgc ttgggggatt tttctatagg agggctagtt
     1201 tagttctctt ttttattttt tagtaagaaa ccgagaccaa ggagcgcaag gaggctgatt
     1261 cctgcaaata ggagtttgtt ttcgttttta attcctgtat ttggaagttc agcttgtcta
     1321 tctggggttg caggtatatt tttcttgcta gagttttcta ccgattcgtt tcgaaccgct
     1381 tcttttacag atgatgcttg tgcttcttgt gctggttgtt cagcttgtga atcagctgta
     1441 gcttggctag gtttattttc cgcatcagct actttggtat ctggtttagt agaatcaggt
     1501 ctagcttctg gagctggatc ttgatgttca gggtgagaag cttcattttg atgttcaggc
     1561 ttggaagggg ttgagtctgg tttctcttct gcagttgact catggctagt tccattttga
     1621 gagactcgaa gaacagtagc tgtaagggca ttcaatttca agcctttttc agtccattca
     1681 agtcctttcg ggttggcaat tccgactgat cctgcttggt tttcatctgc caaaacttcc
     1741 gcatttctta gatgtgcaaa ggcagttccc aaattaaatt cgcgagcttt ttcatccgca
     1801 ttgacaaaga ctgcgtagat atcgccgttt ggagcagtga tttgatagcc aatcactaca
     1861 tcctcttttt ccacaccatt ttggcctggg acagtgatga ggtggacacg gtctttgata
     1921 tcttgaagac tcttaagtcg gaaggcatct gtagattgac gaagggcaat caaacctttc
     1981 atatagtcac ggctcttgac attttcagga taagctttac catctgtagc cttagtccag
     2041 tcaaacttgt tgactgcatc actagaatcg taagagtcat ggatgaagta aggatagtca
     2101 aatgggttgc cgtccttatc acgcaacaag tgagatttgt ttggaacctt atcctctgct
     2161 actggagtct tgtaggctgg gtcacggaat tgtttagtac gtccatattc ctgaccggag
     2221 tggataaatg gagttccttg agctgtcaag accatgagat ttccaagtcg taaacgacgg
     2281 tggatttcag catagttctc agccttgctt gggtcttttt tgatagactg ggcaatgatg
     2341 tcaaagaggg tcaagttatc atgggctgcg atgtattgga tgacatctcc agggctgtca
     2401 gcttcaaagt tagttggttg agcaatgaga tttttaaaga tggtgttgac atcacgcttg
     2461 ccacctgtga taaaggcagg ttgaccttcg tttggataac cagatttgag gttgttacgg
     2521 atgtcatctg aaaagacagc gacagtatcg gtatgtttca tccaatcttg gtcagcagct
     2581 ttagtaggca tgttttcatc accggcatag gttctccaac cttcaccaag catgatgagg
     2641 tttggattga gggcgcgtgc agccttgtaa gcttcttcga tagaagcggc gtcatggtct
     2701 cccatcatat cgaaacggaa gccatccact ttgtaggtat caactaggta tttgatagag
     2761 tcaattagga gccgtttggt catatggtgg gttgtcccca agcgtccacc accaaagcta
     2821 gttcgaggtg tgccatcggc atccataaag tggtagtagt ttggttccaa atcttcaaag
     2881 agatcgactt tggctgtgtg gttataaacg acatctagga tagctcccat accacgtttg
     2941 tggatttcgt tgatgaggtt tttaaattct gcgattcgtt tttctggatt cttaggatcg
     3001 cttgagtaca taccagtcaa ggagaagtag ttttgagggt catatcccca gttgtagttg
     3061 ctgttgcttg aagcgtagtc agacaagcgt tcatggtttt tcaattcatt gacaaagtag
     3121 taagacaaga ctggaaggag ctggatatgg gttacaccca agtctttgag atagtctagt
     3181 ttttcaatga aggcttcaaa agtcccaaat ggtttggtca agtcttttgc aatggcagga
     3241 tctgaagtga aatcacgcac atgagcttcg tagataacgg cgtcttcacg agtcttgaaa
     3301 ttgtgaatct taccataagt caagtcttga ggtccgagtt tagctggatc tacaaaggcg
     3361 gctttagcca ctttatgggc atcgtcaatc ttggaatcgt cgctattcca agcagcaaga
     3421 gatttagcgt aaggatcgag tgcaagaaca gttttacctt gacgctcgat ttggtattga
     3481 taatagtagc cagtgaaatc tgtgattccg agtttgtttg tgctgtctag agtttgtttc
     3541 caagttcctc tttccccttt ttcaagagcg acagttccaa ctactttgtc agggtcattc
     3601 ttgtcgtaga caacaacaga aaccttatca gcacttggtg accaaagggt caaatcaact
     3661 tgttttcctt cttcttttag gtcagctccc agtttgccat catagctgta tgtctcatct
     3721 ttcaggcgcc agcttgtttt ggtagtgaat tggtcggaat tgtagctaac agtataagga
     3781 tgttttgtgt cagagaaatc tccgctgtag gtcactttct taccagcttc atcgattgca
     3841 acatcggtaa tagttacctt gtttcctagg tgattagtga tgttggagtg tttgaggata
     3901 tcttcttttt tagcaccgac aagtgttgaa aagctacttt caatgctaga agtgcctacg
     3961 tgttgggctc ctgtcatacg gatatcatgg acatagtatg gatttgtgta aatcgattca
     4021 tcatcgtctt ttaggaaaat ttggctatga tttttcaaat ctgtgaactt ataattttct
     4081 ttacggattt tcacgtcgtc tccttgtttg ctctcatcta gtaataaaaa tccaaattct
     4141 cttgcggctt cattaagagg aatgtcgata tagcggccat atttgcctgt agccgtaaag
     4201 tctgttccgt caggccattg agcgctactt ggatttttca catctcccca gtaccagaga
     4261 gatttcttgt catagttgcc atctgtgcgg tagtagttga cgcgaacagt tcctgcaggc
     4321 tgtggctcgt aagagaaaac cttgtaatct tggtctaacc aagcttcgtt catttttgga
     4381 actagttttt ctacagattt atcgccggtt agattttttc cagctgtatt gttgatgagg
     4441 aagctaattt tcttggcttg ttctcccttt aatttgacat ctaggtaata gccgtagtca
     4501 tctttcttgg catccttgaa ggacaaagct ccgtttggcc agttttcaga tggtttttca
     4561 acatcgtccc aagtccatag tccttgagca tccttgtttt cttcaggaag ttttttgaca
     4621 tggatacgga agtagttatc ttcgatgggc tcttctgcct tagtttcagt tgttactgga
     4681 ctagtagaag tagttggctc acttgaacga tcttgtccag tttgtggtgc tggatcggct
     4741 gggcttgcag caggtttttc ttctgttttc tctagggaag cgtttgcatt tccaggtgaa
     4801 gaaatatcac tttcgttctt accagagcca gctgctgtat cagtaagagg ttgggcaagg
     4861 gtggttgtat ttctgttgtt gggttcgtta gtggttggtg tactttcgtc ggatgagata
     4921 gttggtgtag ccatggcaag caagacaagg cttgcgccga taaggacaga accagttcca
     4981 tttttgaggg aacggatgct gtagaccatt tttttctcag tgtgagatgg tgtttttctc
     5041 ataatgattc tccaatcaat aaatttctat atcagtatag catgtagtaa aacaatatgc
     5101 aagcgttttc tttgatttgt gaaagaaatt cttacttttg agaagttttc cgtactattt
     5161 tatatatcag tataaatgac ggagataaaa atgtcacgta agccaagccg tgttattagg
     5221 aagatgatgt gttctcagct atttttattc agaaattgat ctctaacatt accaataaaa
     5281 aagaaaaata tcttgacaag caagggaaaa ttttgttaca ataatagacg gtacttttta
     5341 cttttggtct ctcaagagtg tacagggacg tgctgacaaa tgttgcaaaa gtacacacag
     5401 atgatatctg tcaccaagtg tatcatcacc aaaaataaaa aaacacagga gaatgtagat
     5461 gcctacaatt aaccaattgg ttcgcaaacc gcgtaaatca aaagtagaaa aatctaaatc
     5521 accagctttg aacgttggtt acaatagtca taaaaaagtt caaacaaacg tttcttcacc
     5581 acaaaaacgt ggtgttgcaa ctcgtgttgg aacaatgaca cctaaaaaac ctaactcagc
     5641 ccttcgtaaa ttcgctcgtg tacgtttgag caaccttatc gaagttactg cctacatccc
     5701 aggtatcgga cacaacttgc aagagcacag cgtggtgctt cttcgcggtg gacgtgtaaa
     5761 agaccttcca ggggtacgtt accatatcgt ccgtggtgca cttgatactg caggtgttaa
     5821 cgatcgtaaa caaggccgtt ctaaatacgg tactaaacgt ccaaaagcat aaggaaaggg
     5881 gataaagaga aatgagtcgt aaaaatagag ctccaaaacg tgacgtattg ccagatccgc
     5941 tatacaattc acaactagtt actcgtctta tcaaccgcgt tatgcttgat ggtaaacgtg
     6001 gtactgctgc ttcaatcgtt tacggtgctt ttgagcaaat caaagaagct actggcaacg
     6061 atgcacttga agtatttgaa acagctatgg aaaacatcat gcctgtactt gaagtacgtg
     6121 cacgtcgtgt tggtggttct aactaccaag tcccagttga agttcgtcca gaacgtcgta
     6181 caacacttgg acttcgttgg ttggtaacaa tcgctcgtct tcgtggtgaa cacacaatgc
     6241 aagaccgtct tgcaaaagaa atcttggatg ctgctaacaa cactggtgca gcagttaaga
     6301 aacgtgaaga tactcaccgt atggctgaag ctaaccgtgc attcgcacac ttccgttggt
     6361 aagataggat gcgaaagcgt taagaaagtc ccagagaaaa tagggaatcg aagcaggttg
     6421 cggttgcaac caatgagatt catctttttc tccagacttt tagcttgagc tcaactaaat
     6481 catgatgcta ggaacggtaa ggatgcaagg taaaaatagg aaactgacgc agtattcgac
     6541 gaatacaagg agttttatct ttttcacgca gcatcccgtt ccagctcaca tcggctaact
     6601 aactttagcc cgggttcaaa ttagctaaat cgattagtat tagctataac tcagcttacc
     6661 atctcgtaag ttgaaaccaa caatagcatg aaaacattga gaacgggtag gtcctgccta
     6721 tccgttttta ttaaaatcgt gttataatag aatagaaatc aaaaataaat aggagaaaca
     6781 aacctcatgg cacgcgaatt ttcacttgaa aaaactcgta atatcggtat catggctcac
     6841 gtcgatgccg gtaaaacaac aactactgag cgtattcttt actacactgg taaaatccac
     6901 aaaatcggtg aaactcacga aggtgcgtca caaatggact ggatggagca agagcaagaa
     6961 cgtggtatca cgatcacatc tgctgcgacg acagctcaat ggaacaacca ccgcgtaaac
     7021 atcatcgaca caccaggaca cgtggacttc acaatcgaag tacaacgttc tcttcgtgta
     7081 ttggatggtg cggttaccgt tcttgactca caatcaggtg ttgagcctca aactgaaaca
     7141 gtttggcgtc aagcaactga gtacggagtt ccacgtatcg tatttgccaa caaaatggac
     7201 aaaatcggtg ctgacttcct ttactctgta agcacacttc acgatcgtct tcaagcaaat
     7261 gcacacccaa tccaattgcc aatcggttct gaagatgact tccgtggtat cattgacttg
     7321 atcaagatga aagctgaaat ctatactaac gaccttggta cggatatcct tgaagaagac
     7381 atcccagctg aataccttga ccaagctcaa gaataccgtg aaaaattgat tgaagcagtt
     7441 gctgaaactg acgaagaatt gatgatgaaa tacctcgaag gtgaagaaat cactaacgaa
     7501 gaattgaaag ctggtatccg taaagcgact atcaacgttg aattcttccc agtattgtgt
     7561 ggttcagcct tcaaaaacaa aggtgttcaa ttgatgcttg atgcggttat cgactacctt
     7621 ccaagcccac ttgacatccc agcaatcaaa ggtattaacc cagatacaga cgctgaagaa
     7681 attcgtccag catctgacga agagccattt gcagctcttg ccttcaagat catgactgac
     7741 ccattcgtag gtcgtttgac attcttccgt gtttactcag gtgttcttca atcaggttca
     7801 tacgtattga atacttctaa aggtaaacgt gaacgtatcg gacgtatcct tcaaatgcac
     7861 gctaacagcc gtcaagaaat cgacactgtt tactcaggtg atatcgctgc tgccgttggt
     7921 ttgaaagata ctacaactgg tgactcattg acagatgaaa aagctaaaat catccttgag
     7981 tcaatcaacg ttccagaacc agttatccaa ttgatggttg agccaaaatc taaagctgac
     8041 caagacaaga tgggtatcgc ccttcaaaaa ttggctgaag aagatccaac attccgcgtt
     8101 gaaacaaacg ttgaaactgg tgaaacagtt atctcaggta tgggtgaact tcaccttgac
     8161 gtccttgttg atcgtatgcg tcgtgagttc aaagttgaag cgaacgtagg tgctcctcaa
     8221 gtatcttacc gtgaaacatt ccgcgcttct actcaagcac gtggattctt caaacgtcag
     8281 tctggtggta aaggtcaatt cggtgatgta tggattgaat ttactccaaa cgaagaaggt
     8341 aaaggattcg aattcgaaaa cgcaatcgtc ggtggtgtgg ttcctcgtga atttatccca
     8401 gcggttgaaa aaggtttggt agaatctatg gctaacggtg ttcttgcagg ttacccaatg
     8461 gttgacgtta aagctaagct ttatgatggt tcatatcacg atgtcgactc atctgaaact
     8521 gccttcaaga ttgcggcttc actttccctt aaagaagctg ctaaatcagc acaaccagct
     8581 atccttgaac caatgatgct tgtaacaatc actgttccag aagaaaacct tggtgatgtt
     8641 atgggtcacg taactgctcg tcgtggacgt gtagatggta tggaagcaca cggtaacagc
     8701 caaatcgttc gtgcttacgt tccacttgct gaaatgttcg gttacgcaac agttcttcgt
     8761 tctgcatctc aaggacgtgg tacattcatg atggtatttg accactacga agatgtacct
     8821 aagtcagtac aagaagaaat tattaagaaa aataaaggtg aagactaatc cgtcctcact
     8881 ctagaaggaa gtcacttagt ggcttccttt tgtctttaga aaatacctct aaatatggta
     8941 aaatagtaga agaataatgt gaggaaaatg aatgtcaaat agttttgaaa ttttgatgaa
     9001 tcaattgggg atgcctgctg aaatgagaca ggctcctgct ttagcacagg ccaatattga
     9061 gcgagttgtg gttcataaaa ttagtaaggt atgggagttt catttcgtat tttctaatat
     9121 tttaccgatt gaaatctttt tagaattaaa gaaaggtttg agcgaagaat tttctaagac
     9181 aggcaataaa gctgtttttg aaattaaggc tcggtctcaa gaattttcaa atcagctctt
     9241 gcagtcctac tatagggagg ctttctctga aggtccatgt gctagtcaag gttttaagtc
     9301 cctttatcaa aatttgcaag ttcgtgctga gggtaatcag ctatttattg aaggatctga
     9361 agcgattgat aaggaacatt ttaagaagaa tcatcttcct aatttagcca aacaacttga
     9421 aaagtttggt tttccaactt ttaactgtca agtcgagaag aatgatgtcc tgacccaaga
     9481 gcaggaagag gcctttcatg ctgaaaatga gcagattgtt caagctgcca atgaggaagc
     9541 gctccgtgct atggaacaac tggagcagat ggcacctcct ccagcggaag agaaaccagc
     9601 ctttgatttt caagcgaaaa aagctgcagc taaacccaag ctggataagg cggagattac
     9661 tcctatgatc gaagtgacga cagaggaaaa tcgtctggta tttgaagggg ttgtttttga
     9721 tgtggagcaa aaagtgacta gaacaggtcg tgttttaatc aactttaaaa tgacggacta
     9781 tacttcaagt ttttctatgc aaaagtgggt taaaaacgag gaagaggccc agaagtttga
     9841 cctcatcaag aagaattctt ggctccgagt tcgagggaat gtggagatga ataacttcac
     9901 acgcgatttg actatgaacg tacaggatct gcaggaagtt gttcactatg agcggaagga
     9961 tttgatgcca gaaggtgagc gtcgggttga gtttcatgct catactaaca tgtcgactat
    10021 ggatgctttg ccagaggtcg aagagattgt tgcaacagct gctaagtggg gacacaaggc
    10081 ggttgctatc acggaccatg ggaatgtcca gtcctttcca catggctata aggcggctaa
    10141 gaaagcggga atccagctga tctatgggat ggaagccaat atcgtggagg accgtgtccc
    10201 tatcgtctat aacgaagtgg agatggactt gtcagaagca acctacgtgg tctttgacgt
    10261 ggaaacgacg ggactttcag ctatctataa tgacttgatt caggttgcgg cttctaagat
    10321 gtacaagggg aatgttattg ctgaatttga tgaatttatc aatcctgggc atcccttgtc
    10381 agcctttact acagagttaa ctggaattac agatgatcat gtcaaaaatg ccaaaccact
    10441 agaacaagtt ttgcaagaat tccaagaatt ttgcaaggat acggtcctag ttgcccacaa
    10501 tgctaccttt gacgttggct ttatgaatgc taattatgag cggcatgatc ttccaaagat
    10561 tagtcagcca gttattgata cgctggagtt tgctagaaac ctctatcctg agtataaacg
    10621 ccatggtttg gggcctttga ccaagcgttt tggtgtggcc ttggaacatc accacatggc
    10681 caactacgat gcggaagcga ctggtcgtct gcttttcatc tttatcaaag aggtagcaga
    10741 aaaacatggt gtgaccgatt tagctagact caacattgat ctaatcagtc cagattctta
    10801 caaaaaagct cggatcaagc atgcgaccat ctatgtcaag aatcaggtag gtctaaaaaa
    10861 tatctttaag ctggtttcct tgtctaatac caagtatttt gaaggagtgc cacggattcc
    10921 gagaacggtt ctagatgccc atcgagaggg cttgatttta ggttcagcct gttcagaggg
    10981 tgaagttttt gacgtggtcg tttctcaagg tgtggatgcg gcggttgagg tggccaagta
    11041 ttatgatttt atcgaggtca tgccaccggc tatctatgca cccttgattg ccaaagagca
    11101 ggtcaaggat atggaggaac tccagaccat tatcaagagt ttgatagagg ttggagaccg
    11161 ccttggcaag cctgttctgg ctacgggaaa tgttcactat atcgaaccgg aagaagagat
    11221 ttatcgtgaa attatcgtcc gtagtttggg acagggtgcg atgattaatc gaactatcgg
    11281 tcatggtgaa catgcccaac cagcaccact tccaaaggct cattttcgaa cgactaatga
    11341 gatgttggat gaatttgcct ttttgggaga ggaactggct cgtaaactgg ttattgaaaa
    11401 caccaatgcc ttggcagaaa tatttgaatc cgttgaagtc gttaagggtg acttgtatac
    11461 gcctttcatc gacaaggctg aagaaacagt tgctgagttg acctataaga aagcttttga
    11521 gatttatgga aatccgctgc cagatattgt tgatttgcgg attgaaaaag aattaacatc
    11581 catactgggg aatggatttg ctgtgattta tctggcatcg cagatgctgg tgcaacgttc
    11641 taatgaacgg ggttatttgg ttggttctcg tgggtctgtc ggatctagtt tcgttgcgac
    11701 catgattggg attacggagg tcaatcctct ctctcctcac tatgtctgtg gtcagtgtca
    11761 gtacagtgag tttatcacag atggttcgta cggttcagga tttgatatgc cccataagga
    11821 ctgtccaaac tgtggtcaca aactcagtaa aaacggacag gatattccgt ttgagacctt
    11881 ccttggtttt gatggggata aggttcctga tattgacttg aacttctcgg gagaagatca
    11941 gcctagcgcc cacttggatg tgcgtgatat ctttggtgaa gaatatgcct tccgtgcggg
    12001 aacggttggt acggtagctg ccaagactgc ctatggattt gtcaagggtt acgagcgaga
    12061 ttatggcaag ttttatcgtg atgcagaagt agaacgcctc gctcaaggag cggcgggtgt
    12121 caagcggaca acaggccaac acccgggggg aatcgttgtt attccgaact acatggatgt
    12181 ctacgatttt acgcctgtcc agtatccagc agatgatgtc acggctgaat ggcagaccac
    12241 tcactttaac ttccacgata tcgatgagaa cgtcctcaaa ctcgatgtac tgggacatga
    12301 tgatccgacc atgattcgaa aacttcagga tttgtctggt attgacccta ataaaattcc
    12361 tatggatgac gaaggcgtga tggcactctt ttctgggact gatgtactag gggtaacacc
    12421 tgaacaaatt ggaacgccta cgggtatgtt ggggattcca gagtttggaa caaatttcgt
    12481 acgtggaatg gtagacgaaa cccatccgac aacctttgcg gaattgcttc agctgtctgg
    12541 tctgtcccac ggtactgacg tttggttggg gaatgctcag gatctgatta agcaaggaat
    12601 agcggaccta tcgactgtta tcggttgtcg ggacgacatc atggtttacc tcatgcatgc
    12661 gggtctggaa cctaagatgg cctttaccat tatggaacgg gtacgtaagg gtttgtggct
    12721 aaagatttca gaagaggaga gaaatggcta tatcgaagcc atgaaggcta ataaggtgcc
    12781 agagtggtat atcgaatcct gtgggaaaat taagtacatg ttccctaagg cccatgcggc
    12841 agcctacgtt atgatggcct tgcgtgtagc ttacttcaag gttcaccatc ctatttatta
    12901 ctactgtgct tacttctcca ttcgtgctaa ggcttttgat atcaagacca tgggtgcggg
    12961 cttggaggtc atcaagcgca gaatggaaga aatctctgaa aaacggaaga acaatgaagc
    13021 ctctaatgtg gaaatcgatc tctatacaac tcttgagatt gtcaatgaga tgtgggaacg
    13081 aggtttcaag tttggtaaat tagatctcta ccgtagtcag gcgacagagt tcctcatcga
    13141 cggggatacc cttatcccac catttgtagc aatggatggt ctgggagaga acgttgccaa
    13201 gcaactggtg cgggcgcgtg aagagggaga attcctctct aaaacagaac tacgcaagcg
    13261 tggtggactc tcatcaacct tggttgaaaa gatggatgag atgggtattc ttggaaatat
    13321 gccagaggat aaccagttga gtttgtttga tgagttgttt taaaaaattg cttaataatc
    13381 tattaaaaga ggctaacgta tatccaatag atttacatta gctttctttt ttgttaaaat
    13441 agtctatgga aagagggtga gagtatgtca aagatgagta taagcatccg tctggatagt
    13501 gaggttaagg agcaggccca acaggtgttt agtaatctgg gaatggatat gacaacagct
    13561 attaatattt tccttcgtca ggcaattcaa tatcagggat taccttttga tgttagacta
    13621 gacgaaaatc ggaagttgct ccaagcgtta acggatttag accaaaatcg taatatgagc
    13681 cagtcttttg aatcagtctc agatttgatg gaggacttac gtgcttaaga ttcgttatca
    13741 taaacagttt aaaaaagatt ttaagttggc tatgaagcgt ggtttgaagg cagaattatt
    13801 agaagaagtt ttgaattttc tggttcaaga aaaagaacat cctgccagat atcgtgatca
    13861 ttcattgacg gcatccaagc attttcaagg agttcgtgaa tgccataccc agccagattg
    13921 gcttttggtt tataaagtag acaagtcgga attgatttta aatttgctga ggacaggcag
    13981 tcacagtgat ttattttaat ctattttaag ggggttctca tgaaactaag aatatttgcg
    14041 gaagataagc cggctaagaa ggtatttgaa tatcaattag aacttgctga tcgtacaatt
    14101 cttctatcga cagcactctt gtcaggtgct attgctttag caggaatctt ttctgctttg
    14161 aaagaaaaat aaaaatagaa aagagaaaac agaatggttt taccaaattt taaagaaaat
    14221 ctaggaaaat atgcgaaatt gttggttgcg aacggaatta acgtgcaacc tggtcacact
    14281 ttggctctct ctattgatgt ggagcaacgt gaattggcac atctaatcgt gaaagaagct
    14341 tatgccttgg gtgcgcatga ggtcatcgtt cagtggacag atgatgtgat taaccgtgag
    14401 aaattcctcc atgccccgat ggagcgtttg gacaatgtgc cagaatacaa gattgctgag
    14461 atgaactatc ttttggagaa caaggctagc cgtcttgggg ttcgttcatc tgatccaggt
    14521 gccttgaacg gagtggacgc tgacaagctt tcagcttctg ctaaagctat gggacttgcc
    14581 atgaagccta tgcgtatcgc aactcaatct aacaaggtta gctggactgt agcagccgct
    14641 gctggacttg agtgggctaa gaaagtcttc ccaaatgctg cgagcgacga agaagcagtt
    14701 gatttccttt gggatcaaat cttcaaaact tgtcgtgtct acgaagcaga tcctgttaag
    14761 gcttgggagg aacatgcagc cattctcaag agcaaggccg atatgcttaa taaggagcaa
    14821 ttttcagccc ttcactacac agcgccagga acagatttaa cacttggttt gccaaagaac
    14881 cacgtttggg aatcagctgg tgctgtcaat gcacagggcg aagaattctt gccaaatatg
    14941 ccgacagaag aggtcttcac agcgcctgac ttccgtcgtg cagatggtta tgtcacttct
    15001 acaaaaccgc ttagctacaa cggaaatatc attgaaggca ttaaggtgac ctttaaggat
    15061 ggacaaatcg tagatatcac tgctgagaag ggtgatcagg ttatgaaaga ccttgtcttt
    15121 aaaaatgcgg gtgcgcgtgc cttgggtgaa tgtgccttgg taccagatcc aagtccaatt
    15181 tctcagtcag gcattacctt ttttaacacc cttttcgatg aaaatgcgtc aaaccacttg
    15241 gctatcggtg cagcctatgc gactagcgtt gttgatggag cggagatgag cgaagaggag
    15301 cttgaagctg cagggcttaa ccgttcagat gttcacgtag actttatgat tggttctaac
    15361 caaatggata tcgatggtat tcgtgaggat ggaacgcggg tacctctttt ccgtaatggg
    15421 aattgggcaa attaaggaga taatatgtta ggaagtatgt tcgttggtct cctagtggga
    15481 tttttagcag gtgctatgac caatcgtgga gagcgaatgg gatgttttgg aaaaatgttt
    15541 ctcggttgga tcggagcctt tctaggtcac ttgctctttg gaacttgggg gccagtttta
    15601 tcaggaacag ctattatccc agcgatttta ggagccatga ttgttttagc tattttttgg
    15661 agacgaggaa gttaatttcc taaatctgat actcaatgaa aatcaaagag caaactagga
    15721 aactagccgc aggttgctca aagcactgct ttgaggttgc agatagaact gacgaagtca
    15781 gtaacatata tacggcaagg cgacgttgac gcggtttgaa gagatttttg aagagtatga
    15841 aacgaaaagg aggttggtca ttgtactagc ctccttttga tatgatataa tagttctatg
    15901 agattagata aatttttagt tgcctgtgcg gtgggaagtc ggactgaggt caaaaacttg
    15961 ctcaaggctg ggcgcgtgac tgtaaatggt aaaaaagaaa aatcagctaa attgcagatt
    16021 gatgaaaaaa tagatgagat tcgctttgat gggcaagtgt tggagtatga agagtttgtc
    16081 tactacatga tgaacaagcc caaaggagtt atctcagcga ctgaggatcc caagcacaga
    16141 accgttctgg acttgttgga tgacttggcg cggagtaagg aagtttttcc agtaggacgc
    16201 ttggatattg acacgcatgg tcttttgctc ttgaccaata atggtcagct ggctcatgtt
    16261 cttctttcgc ccaagcgtca tgtggacaag acttatcagg ctcaggtcaa gggaattatg
    16321 acccaagaag atgtggagac atttatcaag ggcattccgc tcaaagactt tacctgtcag
    16381 cccgctagac tggagattct ttccacagat gcagaaaaga atcagagcca aatccgtgtg
    16441 accattgcag aagggaagtt tcatcagatc aagcgtatgg tgggctactg tggcaaggaa
    16501 gtggtggact tgcaacgatt gactatggga actttagtat tagatgagaa cctggaacga
    16561 ggggaatggc gtcgcttgac caaggaagaa ttagaaattc tccgcgctaa tattatttaa
    16621 tttagtttaa tactcaatga aaatcaaaga gcaaactagg aaactagccg caggctgtac
    16681 ttgagtacgg caaggcgacg ttgacgtggt ttgaagagat tttcgaagag tataaattcg
    16741 aaaaaggtga gggacaatgt cctcgccttt tatgtttttt agttgcttcc tttgtgaaaa
    16801 gagttataat agactgtaga ataaaaggag gaatctatga acgcgattca agaatcattt
    16861 actgataaac tatttgccaa ctatgaagca aatgtaaaat accaagcgat tgaaaatgct
    16921 gccagccaca acggaatttt tgcagctctg gaatgtcgcc aaagccatgt agacaacaca
    16981 cctgttttct cattggattt aaccaaggac aaggtcacta accagaaagc gtctggtcgt
    17041 tgctggatgt ttgcggctct caacaccttc cgccacaaac tcatctcgca atacaaattg
    17101 gagaactttg agttgtcaca agcccacact ttcttctggg ataagtatga gaaatcaaac
    17161 tggttcttgg agcaagtcat tgcgacttca gaccaagaat tgactagccg caaggttagc
    17221 ttcttactcc aaacacctca acaagatggc ggtcaatggg atatggtcgt ttccctcttt
    17281 gaaaaatacg gtgtcgtgcc taagtcagtt tatcctgagt ctgtttcatc tagcagcagt
    17341 cgtgagctaa atgcgatcct taataaattg cttcgtcaag atgctcaaat cttgcgtgat
    17401 ttgcttgttt ctggtgcaga tcaagcgact gttcaagcta agaaagaaga cctcttgcaa
    17461 gaaatcttta actttcttgc tatgtcatta ggacttccac cacgcaagtt tgactttgct
    17521 tatcgcgata aagataacaa ctataaaagt gaaaaaggaa tcacaccaca agagttttac
    17581 aagaaatatg tcaatcttcc tttagaagac tacgtttctg ttatcaatgc tccaactgct
    17641 gataaacctt acggaaaatc ttacacagtt gagatgttgg ggaatgtggt tggtagccgt
    17701 gcagttcgct acatcaacgt tccaatggag cgcttgaaag aattggcgat tgcccaaatg
    17761 caagcaggtg agactgtttg gtttggttct gatgtcggcc agctcagcaa ccgtaaggct
    17821 ggcatccttg cgacagatgt ttatgacttt gaatcaagca tggacattaa acttactcaa
    17881 gacaaggctg gacgtttgga ctatagcgaa agcttgatga cccacgccat ggtcttgaca
    17941 ggtgttgact tggacgaaaa tggtaaatca accaagtgga aggttgaaaa ctcatgggga
    18001 gacaaggtcg gtacagatgg ttactttgtt gcctcagacg cttggatgga cgaatacaca
    18061 taccaaatcg ttgttcgtaa ggaattgctg acagcagaag aacaagctgc ctatggagca
    18121 gaaccaatcg tacttgcacc atgggatcca atgggagcct tggctgaata aaagcataga
    18181 aaaaaggaat cagattttag aacctggttc ctttttagtt gcttgattac atgatgtgaa
    18241 gaacatgtgc cacaataccc actgcgaaga gggcaaggat aatagtgatt ggagatactt
    18301 ttttcttaag taagtacatg caaagtaaag taaggagtag tcctgataat ccaggaatca
    18361 acatatccaa gttttgttgg aaagtagtaa ctttttcagg agtttgagac aatccttgtc
    18421 ctacttgtgc gaatgcttct tggatacctt tagacccttc tggcaattta tcccaatgga
    18481 tataagcctt ttcatctagt tgaactttag aaacatcgaa agcaaattta atatttaccc
    18541 agcgttgaac aaggacagca agaatgaaca tcccaaggat agaagctcct ttagtgatat
    18601 cttgaaggat accaccagac atatctttag tgatttctga tccagccttg tatccaatct
    18661 cttgaacata ccacaagaat gacatacgaa tcaagttcca tgcaacaaag aagaggagtg
    18721 gccccaagat attgccagta agggcaagtg aagcaccgag agatccaagg attgggcgta
    18781 ctgtaaacca gaatactggg tcaccgatac cagcaagagg tcccatcata ccgattttaa
    18841 ccccttggat agcagcgtca tcgatttcca caccgttagc acgttcttct tcaagcgcaa
    18901 gagtaacccc catgactgga gcagctacgt atggatgagt gttgaagaac tcaaggtgac
    18961 gctcaagagc agcgatttga tcttcttttt tagtatagag ttttttgata gctggaatga
    19021 gtgtataagc ccagcccaag ttttgcatcc gttcaaagtt ccaagaccct tgtaagaagg
    19081 ttgaacgcca ccaaactttt ttacgatctg atttagttaa ttgaagtttt tcagtcatga
    19141 tgttttcagt cctttcttat cttagtagtc ttctaggata tcgccgattg ggtcgttaga
    19201 agttgcggct cctccgccac catttccacc agttttagaa aggtgaaggt agataagagc
    19261 gatagcaaca ccgatagcac cgaatccgat tagagtaata tctgacacag cagcaagaac
    19321 gaaaccaaga gcgaagaatg gccatacttc acgagttgcc atcatgttga taaccatggc
    19381 gtaaccaacg gcaacgacca taccaccacc gatagccata ccatctttga gccagtctgg
    19441 catggcacta aggatacttt gtacagtttc agttggtacc ataaggagaa gagctgcagg
    19501 aagcgcgata cgaagtcctt ggaaaagtag cgcaatgaaa tgagcacgct ccacagcgcc
    19561 gaagtcacct tttttagcgg cagcatcagc agtgtgaacc aatccaactg aaattgtacg
    19621 aacaatcata gttaagaata gaccagctac ggcaagaggg atagcaaccg cttgggcaac
    19681 accgatacca gtcttggtaa agtcaccacc aagaaccatg ataatggcag cagcgacaga
    19741 agcaagtgca gcatcaggag cgatagcagc accgatattt gaccaaccaa gggcaatcat
    19801 ttgaagcgat ccaccgagga taatccctgc ttccaagtga cctgttacaa gcccaataag
    19861 ggtacaggct acaagtggtt ggtgaaattg gaactggtcg aggatgcctt caagacctgc
    19921 aaagaaggct acaacgacta ctaaaaccat agaaataata gacatgttta aaatcctttc
    19981 ataaataatg gcttatttga cattggcttt gttaatcaag tcaaacaaat cttttttaga
    20041 atcatttggt actttacgga catcaaattc aacacccaag tcacgcattt tttcaaatgt
    20101 agcaacatct tctttgtcca tagacaaaac ggtattgacc aatgttttac ctgttgagtg
    20161 agccatagaa ccaacgttaa gagtcttgat tggcacgccg ccttcgatgg cacgaagggc
    20221 atcttgaggt gtttcaaaca agataagggc atgtgtttct ccaaaacgtg ggtcttttga
    20281 aatctcaatc agtttttgaa ttggaaccac gttagccttg acattacctg gagctgcttg
    20341 tttaatcaat tctttacgaa ggtcgtcttt agccacgtta tctgaagcaa cgatgatacg
    20401 atttgctttt gaatctggag tccaagcagt tgcaacctga ccgtgaagta gacgtgtgtc
    20461 aagacgggca agattgattt tcaatttacc gtctccgata acagttcctt ctgggatagc
    20521 agtttgggca actggagcag ctgcagcgct tgcaacttct tcaactggat ttagctcttc
    20581 tggaagagct ttgatgccat ctttggcttc tttaatgata ttagcagcga ctttttctac
    20641 acctgcagca gcgtccatga ggcgctctgt gtaggcttga atcaacatcg gtaagttaag
    20701 tcctgtgatg atggcaaact tacgctcagg attttctccc atcacgcgac tagcttggtt
    20761 aaatggagaa ccactccaaa ggtcagccaa aactagaacc tcatcttctg cgtcaaatgc
    20821 agcaacagcg ttattaaact tagcgtatag atcatcagga ccttcatttg gcataaaggt
    20881 cacaacttga accttttctt gttcaccaaa gatcatagat cctgactgat gaatacccgc
    20941 agcaaattcg ccgtggctcg caataatgat tccgatactc attattgtca ttcctccttt
    21001 tttgttttag ttttcattta agaaaacttt aagactgttt aagtataaac cgttttcata
    21061 aaaaaagcaa ctatttatca taaaaaatta aaaaattttt atttttgtat gttgatatgt
    21121 tgagtttttg aggagtaatc ttgaattctt atttaaaatt taatataaaa aagttggaag
    21181 aagcttccaa cttttaaaat aggtttctat taaattagtg ggtgaagtcg agtaccatac
    21241 gtccttggat ttggcctttt tccatttcgt cgaaaatggc aacagcatct tctactggac
    21301 gtttttgaac aactgggact accagacctt ctgcaccaaa ttggaaggct tcttctaagt
    21361 ctttacgagt tccgacaaga gaaccgatga cttggattcc atcgaggact gttttaacga
    21421 tgctgagttc catcatttca gaaggaagac caacagcgac gacgcgacca ccagcacgaa
    21481 tggagtcaac agcctggttg aaggcaactt tagacacagc agttacgaca gctgaatgag
    21541 ctcctccatc agttttttct ttaatgagtc cagctacatc ttcaacttcg aggccgttaa
    21601 tcacaatgtc agcgcctact tcttttgcaa gggtaagttt gtcattgttg atatcgactg
    21661 cgataacatg agcattgaat acttttttag cgtattgaac agcgaggtta ccaagtccac
    21721 cagcaccgta aagaacaacc cattggcctg gttcaacttt tgcttctttg atagctttat
    21781 aggttgttac tccagcacat gtgatagaag aagcttgggc tggatcaagt ccgtcaggaa
    21841 ctttgacagc atagtcagca gttacgatac attgttcagc cataccaccg tctactgagt
    21901 agccagcatt tttcactgta cggcaaaggg tttcgcgacc agttgtacag tattcgcaag
    21961 tgccacatcc ttcaaagaac caagcaacgc tgacgcggtc accgacttta aggcttttca
    22021 catctggagc aatctcttta acgataccga taccttcgtg cccaagaaca cgtcctggga
    22081 cttgaccaaa gtcaccatga gcaacgtgga ggtcggtgtg gcaaacgcca cagtattcaa
    22141 cttctacaag tgcttcccca gtttcaagtg gacggagtac tttttcttca atagcaacac
    22201 cagtgctttc tggatttaca acaacagctt tcatagctat cctccttgat attgaccgag
    22261 aacagggaca acgggactgg attgattttt tgtcaacaga gtcgagtgtg acgagctctc
    22321 ttgtatttat atgtgaagta tatcacaaaa ggaagccttt tccaaggttt tggagacaaa
    22381 aagtagaaca atcgattaac tggttgatga gactgtgaaa agagcacaaa gaccagcttg
    22441 caagctggtc atactcttcg aaaatctctt caaaccacgt cagcttcatc tacaacctca
    22501 aagcagtgct ttgagcaacc tacggctagc ttcctagttt gctctttgat tctcattgag
    22561 tatcagtata ggttataaga ataagtcttg tagggttttg gcaaccccat cttggtcgtt
    22621 ggtaagggaa atttgctcat ctgcataagg gagtagctct ggattggcat ttttcatggc
    22681 ataacccttc ccagcaaaag cgagcatttc ggtatcattg tgttcatctc caaaggcaat
    22741 caaatctttt ttgtcacgat tcattatctt gagcaagtag tccaaagcaa aggccttgtt
    22801 gacacctttt ggggtacatt caaggatatt gagcggacct ccccaggtat tgatagaaag
    22861 ttgatgctgg tagaaggcgt tcatttcttt tgccaaggca tatttgtcac tggctctggt
    22921 ctgcaagagg atacagttag ggtccttggt caccaattca ggctggaatt gatcttcagg
    22981 ctggaaagct tctacaccaa atagtttggg attggcaatt tcttcattgg gatttgtaat
    23041 gtagaatttt ttacgatatt ctccagcgat aaaatcggct tgaatgtcct ctgaacgttg
    23101 aaccatatct agcagatatt ttttgtctac agtcaaacac ttttcaaaat cccaaacttg
    23161 gtctggtaaa tgagtaaggg atccgttgaa gttaatcata ggagtgtcta agcccagttc
    23221 acggtaaaaa tcttttgaca tacggtaagg gcgacctgtc gtaataataa cctgatggcc
    23281 tttttcagca acttttttga tggttctttt ggtaaagtca gaaatttgac tgtctgagtt
    23341 gagcagggtt ccatccaggt caactgcaat aatttttttc gtcatatgga cctttctagt
    23401 gtgttttcag ataagatgtc ttctattata acagaaagca ggcagaaaag cagattccaa
    23461 acaaaaaatg aaattggatt aatttcttaa acaaatcaaa caaagacatt gaaaaagtga
    23521 atgataaatg atataattct attattgttc gtaaaaatta aaaggagatt gatgatggac
    23581 aaattattta aactaaaaga gaacggtaca gacgttcgta cagaggttct cgctggttta
    23641 acaactttct ttgcaatgag ctatattctc tttgtaaacc cacaaatact ttcacaaaca
    23701 ggaatgcctg ctcagggcgt cttcctagcg acgattattg gtgcagtagc gggtaccttg
    23761 atgatggctt tttatgctaa cttaccttat gcccaagcac caggtatggg actcaatgcc
    23821 ttctttacct ttacagttgt attcgggctt ggttattctt ggcaagaagc cctagctatg
    23881 gtcttcatct gtgggattat ttcattgatt attaccttga caaatgttcg taaaatgatc
    23941 attgaatcga ttcccaatgc tcttcgctca gctatttcag ctggtatcgg tgtcttcctt
    24001 gcctatgtag ggattaagaa tgctggactt ttgaaattca cgattgatcc aggcaactat
    24061 actgttgtag gagaaggggc tgacaaagct caagcaacga ttgcagcaaa ctcttcagca
    24121 gttccaggat tggtcagctt taataatcca gctgttttag tggctcttgc aggacttgcc
    24181 attactatct tctttgtcat caaagggatt aaagggggaa ttattctctc tatcttgaca
    24241 acaactgttc ttgctattgc agttggtttg gttgatttgt ctagtatcga ttttgctaat
    24301 aaccatgttg gtgcagcttt tgaagatttg aagacaatct ttggtgcagc tcttggttca
    24361 gaaggtttgg gagctttggt ttcagataca gctcgcttgc ctgaaactct gatggccatt
    24421 cttgccttct cattgacaga tatttttgac acaattggta ccttgatcgg tacaggtgaa
    24481 aaagttggta ttgtagcgac aaatggtgaa aatcaccaat cagccaaatt ggataaggct
    24541 ctttactctg atttgattgg aacgacagtc ggtgccattg caggtacttc aaacgtaacg
    24601 acttatgttg agtctgctgc tggtatcggt gcaggtggac gtactggttt gacagccttg
    24661 gttgtagcta tctgttttgc gatttcaagc ttctttagcc cacttctagc gatcgtacca
    24721 acagcggcta cagctccaat cttgattatc gttgggatta tgatgcttgg tagcttgaaa
    24781 aatatccatt gggatgatat gtctgaagca gttcctgcct tcttcacatc tatctttatg
    24841 ggattcagct actctatcac tcaagggatt gcagttggtt tcttgactta cactttgact
    24901 aagcttgtca aaggtcaagt taaagatgtt catgccatga tttggatttt ggatgccttg
    24961 tttatcctta actacatcag catggcctta taatagaatg acccaggggg atttcccccc
    25021 ttttttaata caaaggagat aggtgatgaa agagaaaaat atgtggaaag aattgttgaa
    25081 tcgtgcaggc tggattttgg tctttttact tgccgtcctt ttatatcagg ttcccctagt
    25141 ggttacctct attttgactt taaaagaagt agccctgcta cagtcagggc tgatagttac
    25201 tggcctttca attgtggttc tggctctatt tattatggga gctcgtaaaa ccaagttagc
    25261 tagttttaat ttttcttttt ttagagctaa agatttggca cgtttgggct tgagttattt
    25321 agttattgtc gggtcaaata tacttggttc tatcttgttg caactgtcaa atgagacgac
    25381 aacagctaac cagtctcaga ttaacgatat ggttcagaat agttctctga tttctagctt
    25441 cttcttgcta gccttgcttg ctccaatttg tgaggaaatc ttgtgccgtg ggattgttcc
    25501 taaaaagatt ttccgaggca aggagaactt gggatttgta gtcggtacga ttgtgtttgc
    25561 tttattgcat caaccaagta atttaccttc tttattgatt tatggaggta tgtcgacagt
    25621 tctatcttgg acggcctaca agacccaacg tttggaaatg tcgatcttgc ttcacatgat
    25681 tgttaatggg attgctttct gtttgttggc tcttgtggtg attatgagtc ggacattagg
    25741 aatttctgtg taaaagtttt tatgtaggaa ccgacctctt tctactaggg aaagatgaat
    25801 gcaatcgtgt ccatcttttt ctttttatgg taaaatagaa aaataatatg atgaaaatcc
    25861 ttgagggagt gaccgatatg tcaagtaaag ccaatcatgc aaagacagtt atttgcggaa
    25921 ttatcaatgt aaccccagac tccttttcgg acggtggtca attttttgct cttgagcagg
    25981 cactccagca ggctcgtaaa ttgatagcag aaggagccag tatgctcgat atcggcggag
    26041 aatcgactcg gccgggcagt agctatgttg agatagaaga ggaaatccag cgtgttgttc
    26101 cagtgatcaa agcgattcgc aaggaaagtg atgtccttat ttctatcgat acttggaaaa
    26161 gtcaggtggc agaggctgct ttggctgctg gtgccaatct agttaatgat atcactggtc
    26221 tcatgggcga tgaaaaaatg gcccatgtgg ttgctaaagc tggagcgaaa gtagtcatca
    26281 tgtttaatcc agtcatggct cgacctcaac atcctagttc gcttatcttc cctcattttg
    26341 gctttggtca aacctttaca gaaaaagagt tagctgactt tgaaacattg ccaatcgaag
    26401 acttgatggt ggctttcttt gaacgagcac tagcgagagc ggcagaagct ggtattacac
    26461 cagaaaatat cctgttggat ccaggaattg gctttggtct gaccaagaaa gaaaatctcc
    26521 tccttttacg ggacctggat aaactacatc agaagggcta tccaatcttt ctcggagtgt
    26581 cgcgcaagcg atttgtcatc aatatccttg aagaaagtgg gtttgaagtc aatcctgaga
    26641 cagagcttgg tttccgaaat cgggacacgg cttcggctca tgtaactagt atcgctgcga
    26701 gacagggtgt agaagtggtg cgcgtgcatg acgtagctag tcacaggatg gcagttgaaa
    26761 ttgcctctgc cattcgtctg gctgatgaag cggaaaattt agatttaaaa caatataaat
    26821 aagatgaaag aaattgaaaa caatcagtgg attgctaact accggacgga tcaaccgcat
    26881 tttggattgg aacgaatggt ggaactgtta gctttgcgtg gcaatcccca tctcaaactc
    26941 aaggtcctcc atatcggagg gactaacggc aagggctcga ctattgcttt tttgaaaaag
    27001 atgctagaaa agctagggct gagagttggc gtgtttagct cgccctatct cattcattac
    27061 acagaccaga ttagcatcaa tggggaatcg atctcagaag cgaggctaga agctctcatg
    27121 gcagactatc agtctttgct ggagggagaa gcggtcgcca atttacaggg cacaaccgag
    27181 tttgagatta tcacagccct ggcctatgac tactttgcct cagagcaagt agatgtggcc
    27241 atcatggaag ttggcatggg tggacttttg gatagtacca atgtctgtca gcccattttg
    27301 acaggaatta caactattgg cttggatcat gtggccctac ttggtgacac cttggaggcc
    27361 atagcagagc agaaggcagg tattatcaaa caagggatac ccttggtaac agggcgtatt
    27421 gctccagaag ccttgactgt gattgaccgc attgcggaag ggaaagatgc gccgagactt
    27481 gcctacggga cagattatca ggttcgtcat caagaaagtg tggtgacagg ggaagtcttt
    27541 gactatacaa gtgctgtcag acaaggtcgc ttccagacta gcctgcttgg tttgtaccaa
    27601 atagagaatg ctgggatggc catagcttta cttgatactt tttgtcaaga agatggtcga
    27661 gagctagcaa gcaatgactt tcttggtcaa gccttggaag aaacaagttg gccagggcgt
    27721 ttggaaatcg tgtcaagaga tcccttgatg attttggatg gagcccataa tccccatgct
    27781 atcaaggcct tgttggtaac cttgcaagaa cgttttgcgg attatcataa ggaaatcctc
    27841 ttcacttgta tcaaaaccaa agccttggag gatatgttgg acttgctggg agccatgcca
    27901 gataccgagc ttactctaac acattttgcg gatagtcggg cgacggatga aagcgtgctg
    27961 aaagaggcag ctaagtctag aaatctcagc taccaagatt ggcatgattt tctagagcag
    28021 aatttgacag ataaaaaaga agagaaacaa acagttagga ttgtcacagg ttccttgtat
    28081 ttcttgagcc aagtgagggc ctatctgatg gagaggaaga acgagaatgg atacacaaaa
    28141 gattgaagca gctgtaaaaa tgattatcga ggctgtagga gagaacgcta atcgcgaggg
    28201 cttgcaggaa acacctgctc gtgtagcccg tatgtatcaa gagatttttt caggtcttgg
    28261 tcaaacagca gaggaacatt tgtcaaaatc ctttgaaatt attgacgata atatggtggt
    28321 agaaaaggat atctttttcc ataccatgtg tgaacaccac ttcttgccat tttatggtag
    28381 agcgcacatt gcctacattc cagatggtcg tgtggcaggc ttgtctaagc tagcccgtac
    28441 ggttgaagtt tattcgaaaa aaccacaaat tcaagaacgt ttgaatatcg aagtggccga
    28501 tgccttgatg gactatctag gtgctaaagg agcctttgtt gtcattgagg cggaacatat
    28561 gtgtatgagt atgcgtggtg ttagaaaacc aggcactgca accttgacga cagtagctcg
    28621 tggtctattt gaaacagata aggacctccg cgaccaagct tatcgtttaa tggggctata
    28681 aaaagaatcc gcttcaagcg gatttttcta gaaaggaatc attatggatc aactgcagat
    28741 taaggatttg gaaatgtttg cctatcatgg tctttttcct agtgagaaag aattggggca
    28801 gaaatttgtc gtttcagcca tcctatccta tgatatgacc aaggcagcta cagacttgga
    28861 tttaacagcc tctgtccatt acggagaatt atgtcagcag tggacgactt ggtttcagga
    28921 aacgagtgaa gatttgattg aaacggtagc ctataaactg gtggaacgta cctttgagtt
    28981 ttatcctctt gtccaagaaa tgaagttgga actgaaaaaa ccttgggcac cggtgcattt
    29041 gtcactagat acttgctcgg taaccattca tcgccgcaag caacgagcct ttatcgccct
    29101 aggaagcaat atgggagata aacaagcaaa cttgaagcaa gccattgaca aactgcgagc
    29161 tcgtggcatc tatattctca aagagtccag tgtcttagcg acggagcctt ggggtggagt
    29221 ggagcaggat agctttgcca atcaagtggt tgaggtggaa acctggctac cagcacaaga
    29281 cttgttagaa accttgttag ccattgagtc agagctggga cgggtgagag aagtgcattg
    29341 gggacctcgt ttgattgatt tggacttgct ctttgtggag gaccagatcc tttatacaga
    29401 cgacctcata ttgcctcatc cttacatagc ggaacgcctt tttgtccttg agtccttaca
    29461 ggaaattgcg cctcatttta tccatccgac attaaaacaa ccgatccgca acttgtatga
    29521 tgctttgaaa aaatagaaaa actctagttt tcagttactt gcaactgaag gctagagttt
    29581 ttaaaatagg tcattttctt ctgggaggag gatagtttct ctaccgtaca tgtctaaaac
    29641 cagtactctt gggggataac gagggtcgaa aggatggtta aagtcaaaat caatggctgt
    29701 agggaggtgt tgacttgaaa agtggaaggt aatctttcct tggttattaa gcaattgaaa
    29761 ctcgagttct tcttccaatt caaagacatt ttttaagaaa tgatcgatga tataccaaaa
    29821 agagtcaatg atgtcatcgg gcaagctggt aacaatgcca aaactagcag accgcatgtg
    29881 ggtattggta aaagccatat ctctgtcccc tttcttttcc cttatcatac agcaaatagg
    29941 attaaaaatc aagaaaaggt gattttttga aaaggatttt aactacaggg aaaaataagg
    30001 aaaaaaattc ccaaaaatct accgaagtta ataggtaaat tcccaaatta acttgattat
    30061 ataactttca gtta
//
LOCUS       DAVAZT010000024        29758 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVAZT010000024 DAVAZT010000000
VERSION     DAVAZT010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29758
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.024"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            132..494
                     /locus_tag="VQT45_001005"
     CDS             132..494
                     /locus_tag="VQT45_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359343.1"
                     /translation="MRLASESRQILDKLKDDVYNKLGYEVSYSSIVSQAVREYVPKKE
                     RIDWIKLKETAIPFSSLKQSNNWEYQTSLMLEKDVLILLSELQNFFLDVFQAKRIHRA
                     FCIRLCLRAQFLLSNNDS"
     gene            902..1201
                     /locus_tag="VQT45_001006"
     CDS             902..1201
                     /locus_tag="VQT45_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359344.1"
                     /translation="MNRNVLNFLRTESAERVSLYIDKANRLEGDVTLLAPSSQDLEDI
                     KNAMFSNPNLELKVARLDVMKKIAYASTRNHYLTGATIFGDISKGTYNCDPKSYV"
     gene            complement(1296..1733)
                     /locus_tag="VQT45_001007"
     CDS             complement(1296..1733)
                     /locus_tag="VQT45_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359345.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLRENYPDFYDKHISNTYTILSISSFLV"
     gene            complement(1864..2498)
                     /locus_tag="VQT45_001008"
                     /pseudo
     CDS             complement(1864..2498)
                     /locus_tag="VQT45_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
     gene            complement(2709..3359)
                     /locus_tag="VQT45_001009"
     CDS             complement(2709..3359)
                     /locus_tag="VQT45_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HET2359346.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRMHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            3471..4313
                     /locus_tag="VQT45_001010"
     CDS             3471..4313
                     /locus_tag="VQT45_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET2359347.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            4389..4826
                     /locus_tag="VQT45_001011"
     CDS             4389..4826
                     /locus_tag="VQT45_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HET2359348.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKKSKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTDIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            4894..5196
                     /locus_tag="VQT45_001012"
     CDS             4894..5196
                     /locus_tag="VQT45_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359349.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(5287..6360)
                     /locus_tag="VQT45_001013"
     CDS             complement(5287..6360)
                     /locus_tag="VQT45_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HET2359350.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDKLAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHKIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            6516..7193
                     /locus_tag="VQT45_001014"
     CDS             6516..7193
                     /locus_tag="VQT45_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2359351.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            7186..8160
                     /locus_tag="VQT45_001015"
     CDS             7186..8160
                     /locus_tag="VQT45_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2359352.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVEMQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQEICIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(8209..10152)
                     /gene="thrS"
                     /locus_tag="VQT45_001016"
     CDS             complement(8209..10152)
                     /gene="thrS"
                     /locus_tag="VQT45_001016"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HET2359353.1"
                     /translation="MINITFPDGAIREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHGDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(10210..10386)
                     /locus_tag="VQT45_001017"
                     /pseudo
     CDS             complement(10210..10386)
                     /locus_tag="VQT45_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
     gene            complement(10393..10533)
                     /locus_tag="VQT45_001018"
     CDS             complement(10393..10533)
                     /locus_tag="VQT45_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HET2359354.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQ"
     gene            complement(10964..11164)
                     /locus_tag="VQT45_001019"
     CDS             complement(10964..11164)
                     /locus_tag="VQT45_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359355.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKGLYINNLL
                     FFTPMVILIVSLLYSYRFRFSL"
     gene            11403..11948
                     /locus_tag="VQT45_001020"
     CDS             11403..11948
                     /locus_tag="VQT45_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001852743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HET2359356.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGSGS
                     LYIDETKTTRLLDTPDFPEEFKSLAKAQADELDLLRTKNNLNWAFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKRNKPD"
     gene            12174..12443
                     /gene="rpsO"
                     /locus_tag="VQT45_001021"
     CDS             12174..12443
                     /gene="rpsO"
                     /locus_tag="VQT45_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HET2359357.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            13259..13873
                     /locus_tag="VQT45_001022"
     CDS             13259..13873
                     /locus_tag="VQT45_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HET2359358.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(14165..14914)
                     /locus_tag="VQT45_001023"
     CDS             complement(14165..14914)
                     /locus_tag="VQT45_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HET2359359.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            15047..17383
                     /locus_tag="VQT45_001024"
     CDS             15047..17383
                     /locus_tag="VQT45_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HET2359360.1"
                     /translation="MDKNKIMGLTQREIKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAVASILTSYMA
                     HSEDKNPTAQAIRQRFQGQVVYPMLSNLPFSSDRKWGAMELEGLGIVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            17485..18162
                     /locus_tag="VQT45_001025"
     CDS             17485..18162
                     /locus_tag="VQT45_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HET2359361.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            18149..18946
                     /locus_tag="VQT45_001026"
     CDS             18149..18946
                     /locus_tag="VQT45_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HET2359362.1"
                     /translation="MLASEVIHAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            18963..20066
                     /locus_tag="VQT45_001027"
     CDS             18963..20066
                     /locus_tag="VQT45_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HET2359363.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLVQDMEAYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            20073..20264
                     /locus_tag="VQT45_001028"
     CDS             20073..20264
                     /locus_tag="VQT45_001028"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359364.1"
                     /translation="MKIKEQTRKLAAGYSKHCFEVVDRTDEVSSKHCFEVVDRTDEVS
                     NHTHGKATLTWFELDFRRV"
     gene            20367..21386
                     /gene="galE"
                     /locus_tag="VQT45_001029"
     CDS             20367..21386
                     /gene="galE"
                     /locus_tag="VQT45_001029"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET2359365.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTATLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAIEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            21388..22341
                     /locus_tag="VQT45_001030"
     CDS             21388..22341
                     /locus_tag="VQT45_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2359366.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRKLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDDRLKKIEFI"
     gene            22493..23158
                     /locus_tag="VQT45_001031"
     CDS             22493..23158
                     /locus_tag="VQT45_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359367.1"
                     /translation="MLSKEDYTEEIGLIKKQNYVEAELYPIVADIIKPTLKDSLSKRY
                     VFGRQRRGLGQIYYGLSNFPDIVILDKTYENKSRKSIKIEEWKKLRGCVEVKNLNYSL
                     ITEEKIKSTISNSFEHITGEMEQLTGEMGQLIGDLLWYKKVIYTNGIEWRFLSLDDKE
                     EIDNTIVEVVNKRIETEEAGNSFDWWKNIKDLSFNYTDICLSKDCRQEWNEFVKRVKE
                     IEW"
     gene            23197..23298
                     /locus_tag="VQT45_001032"
                     /pseudo
     CDS             23197..23298
                     /locus_tag="VQT45_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group 2 glycosyl transferase"
     gene            complement(23349..23555)
                     /locus_tag="VQT45_001033"
     CDS             complement(23349..23555)
                     /locus_tag="VQT45_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HET2359368.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            23607..24083
                     /locus_tag="VQT45_001034"
     CDS             23607..24083
                     /locus_tag="VQT45_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HET2359369.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            24092..24763
                     /locus_tag="VQT45_001035"
     CDS             24092..24763
                     /locus_tag="VQT45_001035"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HET2359370.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDFETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            24894..25232
                     /locus_tag="VQT45_001036"
     CDS             24894..25232
                     /locus_tag="VQT45_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HET2359371.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLADGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            25235..25864
                     /locus_tag="VQT45_001037"
     CDS             25235..25864
                     /locus_tag="VQT45_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HET2359372.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITKHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            26104..27255
                     /locus_tag="VQT45_001038"
     CDS             26104..27255
                     /locus_tag="VQT45_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2359373.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            27568..28317
                     /gene="truA"
                     /locus_tag="VQT45_001039"
     CDS             27568..28317
                     /gene="truA"
                     /locus_tag="VQT45_001039"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HET2359374.1"
                     /translation="MTRYKATISYDGYAFAGFQRQPHARSVQEEIEKTLTRLNKGQAI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFTVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            28307..29080
                     /locus_tag="VQT45_001040"
     CDS             28307..29080
                     /locus_tag="VQT45_001040"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET2359375.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            29058..29519
                     /locus_tag="VQT45_001041"
     CDS             29058..29519
                     /locus_tag="VQT45_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2359376.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
BASE COUNT         8719 a         5366 c         6692 g         8981 t
ORIGIN      
        1 taaattttta gattgtggaa tttttttcaa cttaattctt gatttttttt ctaaattgtt
       61 atatacttaa tttacgggat aacagaatcc cgtcagaaag gggtgataat atgggaaaag
      121 agaatgttag aatgcgttta gcgtctgaat ccagacagat attagataag cttaaagatg
      181 atgtttacaa taaattaggc tatgaagtaa gctattccag tattgttagt caagctgtta
      241 gagaatacgt tcctaaaaaa gaacgtatag attggataaa attaaaagag acagctatac
      301 ctttttcatc gttaaaacag agcaataatt gggagtacca gacatcactt atgttagaga
      361 aagatgtatt aatcttactg tctgaactac aaaatttttt cttagatgtc ttccaagcga
      421 aacgtataca tagggcattt tgtatacgtc tatgtttgag agcgcaattt ttattaagta
      481 ataatgattc ttaatactat caatattaat gcggagtgta atgctccgca aaaataaaac
      541 ctattacggg ataaaaacac tactttattt aggatggaaa taagaacgta ttttttacta
      601 atattgttta gaaaggagtt tctttatgac accagaagaa caaactgctt tggaatactt
      661 ttatgaggaa ctcgagagtt acggtgaaga tgagcaagga gaggtctttg atttgtatga
      721 taattaaatc atctccatag tttctgagaa taattgagaa actatactct aaatcatagg
      781 tttatgtaaa gctagatata cacaaaagga ggtacgaatg aagatgaaag ctagagcttc
      841 accgttgaat tgattttgtt tctagaaaaa atcaataatt agaaaaatac gaggtaaaaa
      901 aatgaataga aatgtactaa attttctgcg aacagaaagt gctgaaagag ttagtcttta
      961 tatagacaag gctaatagat tggagggcga tgtaactcta ctcgcaccta gttctcaaga
     1021 tttggaagat attaaaaatg ctatgttttc caatcctaat ctcgagctaa aagtagcgag
     1081 actggatgtg atgaagaaaa tagcatatgc ttctacaaga aatcattatt taacaggggc
     1141 tacgattttt ggggatattt cgaaaggaac atacaattgt gatcctaaaa gttatgtcta
     1201 atataaggga ggttaatccc tccccttgtt tttgaaaatc gaaaggaaaa gtataaaaat
     1261 gaaagttaat gaatatttct ggagaacgag ctgtcttata ctaaaaaaga agaaatcgat
     1321 aaaatagtat acgtgttaga gatgtgtttg tcgtaaaagt ctggatagtt ttctcttagg
     1381 tagtcagctg tcatataata aaaagtagaa tggcaagcag tgatgattgg cataagagat
     1441 gaaaaacgct gagaactaat gaaggctaag agaacaaaaa atagaaaatc aatggtgaga
     1501 acccctaaat agtagaagcg aatcttttta ttgatttgag gataaatctc agcgaattga
     1561 tgtttgagtc ggacgaccaa gagaaatagc aggagtcctt gagcaaggaa gaaaattaaa
     1621 ccagagagca agagccactc aaaagatgtc tcgagtctag tgataaaaaa tgcaaatagt
     1681 agcaaatcaa taactgcaat tgctataaaa tggattctat agagtttttt catgacaaga
     1741 cctccctctt ttatctaact tcattctact ctaaaagaat gggagttaca actaaaatga
     1801 taaaaatagc agaggggaga ttctcttaag ttggctagta ttctttattt gagtttcctt
     1861 ctattatcta acttcttcat cattccagac aaataaagct ccgattgcat tgaggatata
     1921 aaagatgtat ttaccgatat tggcgaagtt tccttgaata ccagcttttg tcagctgaac
     1981 gaaattgtaa atcaaccaaa agccccactg tccctcattg ccaatgcatt caaagcattg
     2041 gcaatgaggg acagtgcaaa ggcaatagtt gttacgtagg caaggagatt catcttgccc
     2101 ccatatccga tatagttggt cacaaaggca aagaggaagg cgatgatgga aatgatgatg
     2161 gccgccaatt ttacctgttt ttggctcatt tggttgggtc tgccttcttg cgaagctttc
     2221 catttcttta tagcaaaggt ataaatgagg aaggtgacgg gataggtaat gatggccgcc
     2281 ttatttccaa ggatataatc aatagcaccg gacaaaatgg tattaacaat accaaagtaa
     2341 ttttcccatt tgcttaattt ccccgtgaaa cgagtggaca acatggaaat cccaacgttg
     2401 gttacggaaa tcaatccaaa gggtacaaga gctgtccatg gtccccagtc tacaaattta
     2461 tcgaggcgtg agttgaggta accagatgca atcgcaatcc aacgaccaaa gcaaccccga
     2521 agaggtcaaa ctatttagat gtagcaaaaa tttttagtga ttttttcata ggttaaacta
     2581 cctttctttt tttcaaatat tctcccattt ttttttcaaa tattctacca ccaaatgaaa
     2641 gtaaaataaa atgatagaaa taaaaccctg aaaataaaac tttcagggtt ggtaggggac
     2701 ttgagaaatt agttgatttt ctcgacatag agttgttttg caatgtccat attcacttgt
     2761 aaatcctcgt cgttactgag gatagtgaag gtattgctga agccatcaaa ctgcttaact
     2821 tggagctggt caccgatgtg aagtgagtgc ttgtccagat aatggagaat gtcaaaacta
     2881 tcgtgcatcc gagtcaggcg gtaggcgcca gcttccttga tatcagctag tgggaggtta
     2941 ttgatttcaa cgaggagttc tcccttggca ggaatagttc ctccgtgggg gcaggtttta
     3001 gggaaaccta gcagtttatc tagtctttcc acgaacaggt cagagacagt gtgttccaag
     3061 acctcagctt cctcgtgaat ctggtcactt gtatagtcta aatgatgaac tagaaaaact
     3121 tcaatcaagc ggtgcttacg atagagctca gagaccagtt tgagaccgag gtcagtcagt
     3181 agatagccac attccttgtc ctttaggatg agattttcac ttttcattcg tttgatcatt
     3241 tcagttacgg cagggggaga gacttgcatg cgagccgcaa tttccttgtt ggtaatctta
     3301 tgcaggtcta tgccaatttc ataaatacat tttagatagt cttctttgtt tggggtcatt
     3361 cgtttcctct tgtctaatat ctttatctag tatatcaaaa aaagctagat ttctctagct
     3421 gtgacttttt atgttatact tattgcaaga gaaaaaacga ggagatggat atgacgaaaa
     3481 tagctcttct ttcagatatt catggaaata ccaccgcctt ggaggctgtt ttggcagatg
     3541 ctcggcagct aggagtggat gaatactggc ttttgggaga tattctcatg ccagggacag
     3601 ggcgtagaag gattttggac ttgttggatc aactaccgat tacggctaga gttttgggaa
     3661 actgggaaga cagtctttgg catggtgtcc gtaaggaatt ggatagtact cgccctagtc
     3721 aacgctatct cttgcgccag tgccagtatg ttttagagga aatttcccta gaagaaattg
     3781 aagtgctcca caatcaacct cttcaaattc atcgtcagtt tggggatttg acagtgggaa
     3841 ttagccatca tctgcctgat aagaactggg ggcgagagtt gattcatact ggcaaacaag
     3901 aggaatttga ccgcttggtg actcatcctc cctgtgatat tgctgtttat ggacacattc
     3961 accagcagtt gcttcgttac gggactggtg ggcaattgat tgtcaatccg ggttcgattg
     4021 gccaaccttt ctttttggac gctcagctac ggaaggactt gcgggcccag tatatgattt
     4081 tggagtttga tgacaagggc ctggtagata tggacttccg acgggtagat tacgatgtgg
     4141 cagctgaatt gcagctggct aaagacctga gacttcccta ttttgaggtt tactatgaaa
     4201 gtctggtcaa tgggatccac catactcatc atcaggaatt tttgagagaa ttggctcaga
     4261 aagagggttg cgatcgggag ttagacgact ggttgaaaag tggtaacgat tgacattaca
     4321 actaaaaagg gtataataat agaaaaagaa gagtagaggc agggtagcct cgtaaaaagg
     4381 agaagaggat gcaaattcca agtagattta ccattgcgac tcatatgctg ataatcattg
     4441 ccctcgaggg gaagaaaagc aaggtgacca gtgattttct ggctgctagt gtcggggtca
     4501 atcctgtcat tatcagaaag atcttgtccc agttgaagaa ggcagagctg atttcagtag
     4561 cgcgtggaac gggcggaaca gatattgtca aggaccttaa ggatattagt cttttagatg
     4621 tttatcaggc ggtcgaatgt cttggtaaga caggtcaact cttcagtttc catgacaatc
     4681 cgaatccaaa ttgccctgta ggagctcata ttcatgatgt tttggatcaa aaattggaga
     4741 gaattcagtt gactatggag gcagaacttg gtcaaaccag tctagaaaaa gtcgtggccg
     4801 atgcagagag tcagatgaag gattaagagg gataaatgcc ctcttttttc tttggataat
     4861 tatgataaaa tgtagctatt aaaggagtaa gaaatgtatc tcgttatagg aattgtatta
     4921 gcctttatag tgtcattttg gaaggataat agaagtttgt ggaatccagt attattttta
     4981 ttatccctca tttcaagtta tttttatcta tcctaccttt tttataaaaa tggatacgag
     5041 aatgttcagt tagcttttta tgtatttgcc tttgtcttac ttcctttttt gctttttcta
     5101 agtggcatct ttttaatcta taatggggtc attttgttga agcgagaggg acgttccaag
     5161 ccccattatc tctcaatgct ctttgatttt tattgactat tagattctat ttaaaaagac
     5221 ttagaatgca catgaaagta tgtattctag gtcttttgtt ttgtatacat ttaattttca
     5281 agagtattat ctatttttcc atgcctggta acgagtatca atcaataact gggtaaggcg
     5341 acccaaggtt tctctttctt ctggagtgag ggattgagct tggacaaaga gatgatgaat
     5401 gtattcaagc gcctttaagg aagccaagtc attgatagag ctaataccag cctcaagaat
     5461 agtgccaaag aagaggtcga agtagagctg aagttcttcg tcagggactg tggccaccca
     5521 ttctttaaag gttgtgtcta cttgctggct atcactgttg gtcttatcca gttggacgaa
     5581 gtgcttgtcc tcaatctgcc aactaaaggt atcgtgctgg gcgatgccac ccagggcagt
     5641 actctgaacg atgattttgt gagcaggaat ttccagcatc ataccgataa tggaaccttg
     5701 tggaatgaat atcttgcttc tatccattat cctttgataa cccgcagtct gtgtcaattc
     5761 ttgatggaga ccaggtgcat caaatgtata aactgctgtg atctgatttt gcaaactttg
     5821 ctcaatttgg ctagcagcat agatagcgag atttcctccc ttggaatgcc cagctagaat
     5881 aaccttttgc ttaggatgat gggcaaaaaa gttctttaaa tagcgaaggg cgtgcttttg
     5941 agcaggaatt tccttcatat aggtcaggtg gaaatcttcc ttccagccaa tgatactgtc
     6001 atctgtccca cgaaagacaa tcagataggt atcgaggctg acacgataag tcatagccgc
     6061 aaattgcttt tgcagttcag ggtcgatgtc gttgataaaa tgggagagtt tgcaattttt
     6121 gaagcgcttg tgttgagcca atttatctaa taattgaagg cgatttttgc tagtaagcat
     6181 ggtgggctct cttggaacct gaggtgctag atctaaaaga cgttgaggaa gtgtggagac
     6241 cagattatca aaggagaggt aggtgatttc tattaaggtt agaatgtcta actcattcaa
     6301 gggaaggtcg taataagaat catatgcgac atctttcaga tagtcaaaaa tattggccat
     6361 aagagctcct ttctttttat ttatcttagc aaatttccct caaattagct agtagcatag
     6421 cctgtttgca ctggctaaaa acaggctatt tcaaattcag tttcagacca tctagcatgg
     6481 aaaaatctgt tataataatg gaaaaggaga agcgcatgca caagatttta ttaatagaag
     6541 atgatcaggt cattcgtcaa cagattggga aaatgctctc tgaatgggga tttgaagtgg
     6601 tcctggtaga agactttatg gaagttttga gtctatttgt tcagtcggaa cctcatctgg
     6661 tcctcatgga tattggtttg cccttgttta atggttatca ctggtgtcag gaaatccgca
     6721 agatttccaa ggtacctatc atgtttcttt cttcgagaga ccaggctatg gatattgtca
     6781 tggcaatcaa tatgggggcg gatgactttg tgaccaagcc ttttgaccag caggttcttt
     6841 tagctaaggt tcagggcttg ttgcgtcgtt cctatgagtt tgggcgtgat gagagtttgc
     6901 tggaatatgc tggtgttatc ctcaatacca aatccatgga tttacattat caagggcaag
     6961 tcttgaattt gaccaagaat gaattccaga ttttacgcgt gttatttgag catgcaggca
     7021 acatcgtagc acgtgacgac ctgatgcggg aactttggaa cagtgacttt ttcattgatg
     7081 ataataccct ctctgtcaat gtggctcgtt tgcgtaaaaa gttggaggag cagggattgg
     7141 taggatttat cgagaccaag aaaggaatag ggtacggatt gaagcatgct tgattggaaa
     7201 caattttttc tagcctatct gcgctcccgt agtcgtcttt ttatctatct gctttctttg
     7261 gcatttcttg tcttactctt tcagttttta tttgccagtc taggaattta cttcctctac
     7321 tttttcttct tgtgttgctt tgtaaccatc ttatttttca cttgggacat attggtggaa
     7381 atgcaggtct atcgccagga acttctctat ggagagaggg aagccaagtc tcctttggaa
     7441 atagctttag cagaaaaatt agaagcgcgt gagatggaac tctatcagca gaggtcaaaa
     7501 gcagaaagaa aactgacgga tttgctggat tactatacct tgtgggtcca tcagataaag
     7561 acccccattg cagccagtca actcttagtt gcagaagtgg tcgaccgcca actgaagcag
     7621 cagctagaac aggaaatttt caaaatcgac tcttatacca acctagtttt acagtacctg
     7681 cgtttagaaa gtttccatga tgatttgctc ttaaagcagg ttcaaattga ggacttggtc
     7741 aaggaaataa ttcgtaaata tgctcttttc tttattcaaa aaggcttaaa tgtcaatcta
     7801 catgaccttg ataaagaaat cgtgacggat aaaaagtggc tgctagtggt tattgagcaa
     7861 atcatctcaa acagtctcaa gtacaccaag gaaggtggtc tggagattta tatggatgac
     7921 caagagattt gtatcaaaga tacgggaatc gggataaaaa acagtgatgt cctccgagta
     7981 tttgaacgtg gcttttcagg atacaatggc cgtttgaccc agcagtcctc tggacttggc
     8041 ctttatctat ctaagaaaat ttctgaagaa ctggggcacc agattcgtat cgagtctgag
     8101 gtcggaaaag gaacgacagt gcggattcag tttgctcaag tgaacttagt ccttgagtaa
     8161 aaatagatga gaaaaagcct ccagattgga ggcttttatg ctagactctt atttctcaac
     8221 gcgtgatttg ttggcgatat cagctaggat agcttgaaca aaattatcaa ctgagacagt
     8281 ttgtgtttct ttttggccgt agcgacgaac gttgactgtt tcgtcttcca tttctttgtc
     8341 tccaacaatt aattggtaag gaatcttgct ggtttgtgaa gcacggatct tgaactgcat
     8401 tttttcattg cgctcatcta cgtctgcacg gacaccgcgg tcacggagtt tcttggctac
     8461 ttcccaagcg tagtccacgt gtttttcgtt agatactggg atgagggtta cttggtgtgg
     8521 tgccagccat gttgggaagg cccccttgta gttctcaatc aagatagctg tgaagcgttc
     8581 catagttgag ataaccccac ggtggatcat gactggacgg tgatcttcgc catcagctcc
     8641 gatgtatttg aggtcgaagc gttctggcaa caagaaatca agttggatag tagaaagggt
     8701 ttcttctttt ccaagggcag ttttaatctg gatatccaat tttggtccgt agaaggctgc
     8761 ttcaccttcg gcttcaaagt agtccacgcc catttcatca agagctgcac gaagcatggt
     8821 ttgggcattt tcccacatct catcgttatc aaagtactta tgagtatctt gagggtcacg
     8881 aagagagagg cggaagcggt agtcagtcaa gttgaagtct tcataaacat cgataatcaa
     8941 ctgaagggca cgttggaatt cttcttggat ttgttctgga gtaacgaata ggtgaccgtc
     9001 gttgagtgac atttcacgta cacgttgaag gccagtgagg gcaccagatt tttcgtaacg
     9061 gtgcatcata ccgatttcag cgatacggat tggcaattca cggtaagagt gaacatggtg
     9121 tttgaaaact tggatgtggt gcggacagtt cattggacga aggacaaatt cttccccgtc
     9181 acccatgtcc atggttggga acatgtcttc ttggtaatga tcccagtgac cagaagtctt
     9241 gtaaagctca acagaagcaa gtggtggagt gtagacgtgt tggtagccag aagccaactc
     9301 tttgtttacg atgtagcgtt ccaattcacg acggatagtc gcaccatttg gcaaccagaa
     9361 tggcaaacct tgtcccactt cttgtgaaat cataaagagg tcaagctctt taccaagttt
     9421 acggtggtca cgttccttag cttcttcacg catttgaagg tagtttttca agtctttctt
     9481 gtcaaaccaa gctgtaccgt agatacgttg catcatagcg ttgtcgctgt ttccacgcca
     9541 gtacgcacca gctacatgga gaaggtggaa gatttggata cgacctgttg atggaacgtg
     9601 aggtccacgg cagaggtcta catattcacc ctgacgatag atagtcaaac cgccttcgtc
     9661 ttctgagtgt tcttcaatca attccaactt gtaagggtca tttttgaaga tttcacgtgc
     9721 ctcgtcttta gtcacttctt cacgaataga tgggaagttt tctttgacga ttttttgcat
     9781 ttcttcttcg atacgaggaa ggtcttcgtt agagatttga ccagctgtgt tgtcagtatc
     9841 gtagtagaaa ccatcttcga tggctggacc aactcccaag tgaatgtctg ggaaaagacg
     9901 acgagctgct tgggcgaaca agtgagctgc tgagtgacgc aagattggaa gggcatctcc
     9961 gtgatcaggt gtcacaattt cgatgcttcc atcttcagtg atagcgcgag tagtgtcgat
    10021 gagtttgccg ttgaatttac cagccaaggc ttttttagct agggaattgc tgatagattg
    10081 ggcaatttca aaagttgtta cgccagattc gaattcacga atagcgccat ctgggaaagt
    10141 aatgttaatc atgatgttct ccttttttat tatttcatag tttctaagca ttgatttttt
    10201 atcagcagac tacttccaag ttctaacgtt caattgcttt tctttatcag agaggaagtt
    10261 ttccatttcc gtcagaatat ctatatccaa acgttgagaa agttctaata gtcaccagat
    10321 attttctgaa agtttttgtt ccagtgtgta gggtgtttca tcatagtagc gtccttgctt
    10381 tgtcatcacc agtcattgga aatttccaat atcattagat aaagccaaga ggtcttcttc
    10441 taccgtccac ttgaaatcat gatgcttaac ttccagttcg tgataagctt gtcggattgc
    10501 ccaactgcgc tccactaatt cttgcaactc cataattagt atcctaataa aaaaatgcga
    10561 catcctcgaa aggacgtcgc aacgtggttc caccttcatt tatgtacctc aaaagagagg
    10621 gacacctctg atcggctcta acgtggccac cgttttatgt tttcataaaa aactcaagag
    10681 tagtatcagt ttagacttcc tatgcgtttc cagcaaccac gcactctcta gtagaaaggg
    10741 actaagtgac ttgtctctat ggattattat agcatgattg tgagattttt caaggatttt
    10801 gtgaaagttt tttgtttttc attttttgta gaatatgctt gatgctaata ccagaatcca
    10861 tgcccaccag agcaactgtt tcatagatta gcaagtaaat tagtataaac acaccaaagg
    10921 ttatgatagt aaagtaaaag agcagtccgt taccaactaa ccatcaaagt gagaaacgga
    10981 aacggtagct atagagtaac gatacaatca agattaccat aggtgtaaag aagagaagat
    11041 tgtttatata gagtcccttg agtgtaaggg ggtcagaaac aactagcaag aacaactcat
    11101 aaagtggcca ataaaagaat aatatgacca gatagtaggg gagatgggaa tagaatctac
    11161 gcatgataat cacctcgttt taaaaaaaca gacaacttag atctcttgct atgattatta
    11221 tagtatgttt aaaacaagaa agtaaatttg ttgacaaaga agatttttct tttcactaga
    11281 atcatggtta gttttcttgg tagaaatatt ttgataataa ttaagcaaga ctattgacat
    11341 tgattattaa gagtgtcaca attgttgtaa ctaaaataat tacaacaaga ggggtataaa
    11401 aaatgaaact agcagttatt gcagcaaatg gacaagcggg gaaggcaatt gttgaagaag
    11461 cagtcaaacg aggacatgaa gtaacggcta ttgttcgttc tgaaaacaaa agtcaagctg
    11521 agtctattat taaaaaagat ttatttgagt tgacaaaaga tgatcttact ggatttgatg
    11581 ctgttatttc agcgtttggt gcttatacac cagatacgct accgctccac agcaaatcaa
    11641 tcgaactatt taatcagctt cttgctggaa cacagacacg ttttctagtt gtagggggat
    11701 caggaagcct ttatatagat gaaacaaaaa cgacacgact tttagatacg cctgattttc
    11761 ctgaagaatt taagtcacta gcaaaagctc aagcggatga attggatctt cttcgtacaa
    11821 aaaataatct caactgggct tttgtcagtc ctgctgtaga ttttattccc gatggtgaaa
    11881 aaacaggaaa ctacattcta gcaggagaaa tttttactac taatgaaaaa aggaataagc
    11941 cagattagtt atgcagatta tgctattgga ttggtagatg aacttgaaaa aggtcatcat
    12001 ataaaagaac gtatctcttt acttgaaaaa taataactat gagagtatta atgtttgaca
    12061 gaaaatttaa atcttggtag aatagggatt gtcgtaaaga caaataactt cttcttggtt
    12121 acaggcatgc caacctgtca ctcggatgaa gccaaataaa aaggagaaac atcatggcaa
    12181 tctcaaaaga gaaaaaaaat gaaatcatcg cacaatatgc acgtcacgaa ggtgatacag
    12241 gttcagtaga ggttcaagtt gctgtcctta cttgggaaat caaccacctt aatgaacaca
    12301 tcaaacaaca caaaaaagac cacgctactt accgtggatt gatgaaaaaa atcggtcgcc
    12361 gtcgtaactt gcttgcatac ttgcgtaaaa acgacgttaa ccgttaccgt gagttgatca
    12421 actctctagg acttcgtcgc taattcaaga tacaaaggct gtcaaaagca caaagtaaaa
    12481 ataggaaaat ttacgaagaa acttcagttt ctaggagatt ttatcttttt tgccaagtgc
    12541 ttaggccgtg ttcaattgag catatcttga taatgaagct actctaaatt gggtagcttt
    12601 tttgtgttgt caccttacct cgatatactc aagtataatc tttggttacg gttcctagca
    12661 ctgtaaggta aaataaacca gcttttctcc cttcggggag attttttttg tttcactgaa
    12721 agtttcgtac gatcttcgcc tcgtcgccta gtctataaac gatttatcta gcaagaatca
    12781 tgatgctaag ggcgtcaaaa atccgtatga aaatagggaa atgacacagt gttcgatgag
    12841 cacaaggagt ttcatctttt tcactaggat tttagcccgg actcaaatca gctctctgac
    12901 ttcagagggc ttttttattg aggttttatc ggtaacaatt ttggagacta caaaaacctc
    12961 aaacggtatc agctaattac accataaagg tgcgcagtta ctcggctttt caagccgagt
    13021 agttgtatgc aagcccccta gaagagccca ctctttacaa agtaaagtat agtatgttat
    13081 actttacatg gaagtagtca ctgaattcca gttagaaatt actttgtaac tacgttttga
    13141 ggaggagtaa aatgctttcc tacgttcgat attacccact agcgatagct aaattaatgt
    13201 gtctgtgctc tcctaaaatc tgctgattta ttactgacta atacaggagt ttttttttat
    13261 gggacagaca atcatatctg ctattggtgt ttatatttcc accagtatcg attatttaat
    13321 tattttaatt attttatttg cacagctatc acagaataaa cagaaatggc atatttatgc
    13381 ggggcaatat ctaggcacag gcttacttgt aggggcgagt ttagttgctg cttatgtcgt
    13441 taatttcgtg cctgaagaat ggatggttgg attgcttggt ttaatcccta tctatttagg
    13501 gattcgcttt gcaattgttg gagaagatgc ggaagaagaa gaggaagaaa ttattgaaag
    13561 attagaacaa agcaaggcaa atcaactgtt ttggacagtt acattgctga caattgcgtc
    13621 tggcggagat aatttaggta tctatatacc ttattttgct tcgttagatt ggtcacagac
    13681 cctcgtggcc ttgcttgtgt ttgtaatcgg cataattatc ttttgcgaga ttagtcgggt
    13741 gttatcttct attccgttaa tattcgagac aattgaaaaa tacgagcgaa tcattgtgcc
    13801 cttagtattc attctacttg gactatacat catgtatgaa aatggcacga tagagacttt
    13861 tctgatcgtg tagatttttt tgtttcacta ggattttagt ccgagctcaa atcagctctc
    13921 tgattttcag agggcttttt cattgagtat aaatggacaa tcttaaagtt actctattgt
    13981 agagtggctt ttgatttgat taggagattc ttataaatat agtaaaatga aataagaata
    14041 ggacaaatcg atcaggacag tcaaatcgat ttctaaaaat gttttagaag tagaggtgta
    14101 ctattctagt ttcaatttga tatataaatg aaaaccttag ctgtttggcc aaggttcatt
    14161 tcttctatgc aagttcttct cttttcttat ctgggttcca gatgaagctt gcgataaagc
    14221 taaagatgat ggttaggata gcgagaataa tagcaaggat gagggcaggg atgcggataa
    14281 accaccagag tggatttggt tttttatcat tgtgccattg tttcgtttct tcgtccagac
    14341 gttggaattc tgtttgaata cgattggcga ctgtttcaat gccttcatca ttcattttct
    14401 tgatatctga gatatcgatt ggatttccaa agttcatatc gacacgttca cggctaatca
    14461 agcccttcaa agtcatggga ccggtgtagg taaccggcat gatacggacc ttggccattt
    14521 tggcaatcag tgctgcgccc cccttgacat cgtttgagtg gcggctacca cttggaaaca
    14581 tgatgagaga gcggtcactt tttttgagaa cgttgatagg atatttgatg gctgaggcgc
    14641 tgggattttc acggtcgatg ggaaaggcgc cacacatacg aatccaccaa ccaaagatac
    14701 ggttggtaaa gagttctttt tttgccataa agatgaactg ttttggcttg gtcgcaaagg
    14761 ccatataaac aggatcccac caggtacggt gaggcgcaac taaaatataa ttttcatctt
    14821 gattaggaat tttatcagta ttatgatagt gagcattgcc attgatggac cataagagca
    14881 atacaactaa tccacgcaaa taagtataaa acatgcgatc tccttcgatt gttttcttgt
    14941 tattattata ccttatcaaa ggagggctgg caaacttttc ccttgactag atgcatattt
    15001 gggatgaaat tagaattctg ttaaaaaaaa tgatataata gaatttatgg ataaaaataa
    15061 gattatggga ttaacccaaa gagaaatcaa ggaaagacag gctgagggtt tggtcaatga
    15121 ctttaccgca tcagccagta ccagcacttg gcaaatcgtt aaacgaaatg tctttaccct
    15181 ttttaacgct ttgaactttg ccattgcttt ggcccttgcc tttgtgcagg cttggagcaa
    15241 tctggtcttc tttgctgtta tctgctttaa cgctttttct gggattgtga ccgagctacg
    15301 agccaaacac atggtggaca agctcaatct catgaccaag gaaaaggtca aaaccatccg
    15361 tgatggtcag gaagttgctc ttaatcctga agaattagtg ctaggagatg tcattcgttt
    15421 gtctgcagga gagcagattc ctagtgatgc cttggttttg gaaggctttg cggaagtcaa
    15481 tgaagccatg ttaacgggag aaagtgattt ggtgcaaaag gaagttgacg gcttactttt
    15541 gtcaggaagt ttcctagcca gtgggtcagt tttatctcaa gttcaccatg tcggtgcaga
    15601 caactatgct gccaaactca tgcttgaggc taagaccgtt aaacccatca actcccgtat
    15661 catgaaatcg ctggacaagt tggctggttt tactgggaag attatcattc cctttggtct
    15721 ggctctcttg ctggaagcct tgcttttaaa aggcctgcct ctcaagtcat ccgttgtaaa
    15781 ctcgtcgaca gctcttttgg gaatgttgcc taagggaatt gcccttttga ccattacttc
    15841 gctcttgact gcagtgatta agttgggctt gaaaaaggtc ttggtgcagg agatgtactc
    15901 tgttgagacc ttggcgcgcg tggatatgct ctgtctggac aagacgggta ccatcaccca
    15961 aggaaagatg caggtggagg ctgttcttcc actgacggaa acttatggtg aagaggctgt
    16021 tgccagcatc ctgaccagct atatggccca tagtgaggat aaaaatccaa cagctcaagc
    16081 cattcgccag agattccaag gtcaagtagt ctatcctatg ctctctaatc ttcccttctc
    16141 cagcgaccgc aagtggggag ccatggagtt agaaggtttg ggaatagttt tcttaggggc
    16201 acctgagatg ttgctggatt ctgaggtccc agaagccaga gaggccttgg agagaggatc
    16261 acgtgtcttg gtcttagctc tcagtcagga gaaattagac catcacaaac cacagaaacc
    16321 atctgatatt caggctctag ccttgctgga aatcttggat cctattcgag agggagcggc
    16381 agagacgctg aactatctcc gttctcagga agtggggctc aagattatct ctggtgacaa
    16441 tccagttacg gtatccagca ttgcccagaa ggctggtttt gcggactatc acagctatgt
    16501 cgattgttca aaaatcacgg atgaggaatt gattgctctg gcggaggaga cagcgatttt
    16561 cggacgtgtt tcccctcatc aaaagaaact cattatccaa acgctgaaaa aagcgggtca
    16621 tacaacagct atgactgggg atggagttaa tgatatcctg gctcttcgtg aggcggattg
    16681 ttctatcgta atggcggagg gagacccggc aacccgtcag attgccaacc tggttctctt
    16741 gaactcagac tttaatgatg ttcctgagat tctttttgaa ggtcgtcgtg tggtcaataa
    16801 cattgcccac atcgctccga ttttcttgat aaagaccatc tattccttcc tgttagcagt
    16861 catctgtatt gccagtgctt tactaggtcg gtcagagtgg attttgattt tccccttcat
    16921 tccgatccag attaccatga ttgaccagtt tgtggaaggt ttcccaccat tcgttctgac
    16981 ttttgagcga aatatcaaac ctgttgagcc aaatttcctc agaaaatcca tgcttcgtgc
    17041 cctaccaagt gccctcatgg tcgtgtttag cgttcttttt gtgaaaatct ttggaacgag
    17101 tcaaggttgg tctgagttag aaatctcaac tctcctctat tatctcttgg ggtcaattgg
    17161 tttcttatcc gtatttagag cctgcatgcc attcactcta tggcgagtcc tcttgattgt
    17221 ctggtcagta ggaggcttcc tagccacagc tctcttccca agaatccaaa aactgcttga
    17281 aatttcaacc ttgacagaac aaacgttgcc tgtttatggt gtcatgatgt tggtctttac
    17341 agtgattttc atcctgacta gtcgctatca agctagaaaa taaagaaaga ctgcaatctg
    17401 tggattgcag tttttttagg tacaagattg ccagccgaaa tgtggtataa taagaggtaa
    17461 tagagttttg gaaagtgaga gaagatgatt tcaaagagat tagaattggt agcttccttt
    17521 gtgtcacagg gggctatttt actagatgtg ggaagtgacc atgcttatct gcctatcgag
    17581 ttggttgaga gaggccaaat caaaagcgct attgcaggtg aggtggtgga aggtccctat
    17641 cagtctgcgg ttaaaaatgt tgaggctcac ggcctaaagg agaaaatcca agtccgttta
    17701 gccaatggct tggcagcttt tgaagagact gaccaagtgt ctgtcattac cattgctggc
    17761 atgggtggtc gtttgattgc taggatttta gaagaaggtt tggggaagtt agctaatgta
    17821 gagcgtttga tcctccagcc caataatcgt gaagacgact tgcgtatctg gctacaggat
    17881 catggattcc agattgtagc agaaagcatc ttagaagaag ctggaaagtt ttatgagatt
    17941 ttggtggtgg aagcaggaca aatgaagcta tcagccagtg atgttcgctt tggtcccttc
    18001 ttgtccaaag aagtcagtcc agtatttgtc caaaaatggc aaaaagaagc tgagaagcta
    18061 gagttcgctc tcggacaaat cccagaaaaa aatctggaag aacgtcaagt tctagtagat
    18121 aagattcaag ctatcaagga ggtgctccat gttagcaagt gaagtgattc atgcttatga
    18181 agccttttgc cctcaggaat tttctatgga gggagacagc cgtggtctgc aaattggcac
    18241 tttagacaag ggtatccaaa gggtcatggt tgccctcgat attcgtgaag agacagtggc
    18301 agaggccatt gaaaagggtg tggacttgat tatcgtcaag cacgcgccta tctttcgtcc
    18361 tatcaaggac ttgcttgcca gccgtccgca aaatcagatt tacatcgacc tgattaagca
    18421 tgacatcgca gtttatgtca gccataccaa tattgatatc gttgaaaatg ggctcaatga
    18481 ctggttttgt cagatgctag gaatcgagga gacgacttat ctgcaggaaa caggtccaga
    18541 acgtggaatt ggacgtattg ggaatattca gcctcagaca ttttgggaat tggcccaaca
    18601 ggtcaagcaa gtctttgacc tagatagcct tcgaatggtg cattatcaag agaatgattt
    18661 gcagaagcct atttcaagag tagcaatttg tggtggaagc gggcagtctt tctataagga
    18721 tgctttggca aagggggcag atgtctatat cactggtgat atctactacc atactgctca
    18781 ggatatgctg tctgatggct tgttagcatt ggatccaggt cactatatcg aagtgctttt
    18841 tgtggaaaaa atcgcagcac tccttactca atggaaagag aaaaaaggct gggaactaga
    18901 gattttacct agtcaagcat cgaccaatcc tttccgtcat atctagttag aaagtgaaga
    18961 caatgaaaaa agttgccatt attggagcag gaattgtggg agcaacagct gcctactacc
    19021 tctcgagaga aagtgaccta gaggtgaccg tttttgacca tgagcaaggt caagccacca
    19081 aggccgcagc aggaattatc agtccttggt tttccaaacg ccgtaataaa gcctggtaca
    19141 agatggcgcg cttgggggct gatttttatg tggatttatt agctgattta gagaaatcag
    19201 gacaaaaaat cgacttttac cagcgttcgg gagtctttct cttgaaaaag gatgaatcca
    19261 agttggaaga actttatcaa ctggccctcc agcgcagaga agaatctccc ttgatagggc
    19321 aattagccat tctggaccaa gcctcagcta atgaattatt ccctggtttg cagggatttg
    19381 accgcctgct ctatgcttct ggtggagcga gagtagatgg ccaactcttg gtaactcgtc
    19441 tgctagaagc cagtcatgtc aagctggtca aagaaaaagt gactctgaca ccgttagcat
    19501 caggctacca gattggtgaa gaggagtttg agcaggttat tttggcgacg ggagcttggt
    19561 tgggggacat gttagaaccc ttgggttatg aagtagatgt tcgtcctcaa aaaggacaac
    19621 tacgagatta tcagctggtc caagacatgg aagcttaccc tgttgtcatg ccagaagggg
    19681 agtgggattt gattcctttt gcaggtggga aattgtcctt aggcgctacc cacgaaaatg
    19741 acatgggatt tgatttgacg gtagatgaaa ccttgctcca acaaatggag gaggccacct
    19801 tgactcacta tctgattttg gctgaagcta cttcaaaatc tgagcgtgtt ggaatccgtg
    19861 cctacaccag tgatttctct cctttctttg ggcaggtgcc tgacttaact ggtgtctatg
    19921 cagccagtgg actaggttca tcaggcctca caactggtcc tattattggt taccatttag
    19981 ctcaactgat ccaagacaag gagttgacct tggaccctga aaactaccca attgaaaact
    20041 atgtcaaacg agtaaaaagc gaataatact caatgaaaat caaagaacaa actaggaaac
    20101 tagccgcggg ttactcaaag cactgctttg aggttgtgga tagaactgac gaagtcagct
    20161 caaaacactg ttttgaggtt gtagatagaa ctgacgaagt cagtaaccat acccatggca
    20221 aggcgacgtt gacgtggttt gaattggatt ttcgaagagt ataagcattt tactgaaatt
    20281 ttatcaggta gtttaggatg gcaaatgaca ttccctgtca aaaatggtaa aataagaaaa
    20341 aataatctga gaatcgagga aaaaagatgc aagaaaagat tttggtaact ggtggtgccg
    20401 gttttattgg aacccacact gttattgaat tgatccaagc aggccatcaa gttgttgtgg
    20461 tggataatct tgtcaatagc aatcgtaaga gtttagaagt tgttgaaaga atcacaggag
    20521 ttgagattcc tttctatgag gcagatattc gtgacacagc taccctcaga gatattttca
    20581 agcaggaaga accgactggt gtcattcact ttgctggttt gaaggctgtt ggcgaatcaa
    20641 cacgtatccc tcttgcctac tatgacaaca atatcgctgg aactgtcagc cttttgaaag
    20701 ccatagaaga aaacaactgt aaaaacatca tcttcagttc ttctgcgaca gtttacgggg
    20761 atccgcacac agtgcccatc ttggaagatt tcccactttc agtgaccaac ccatacggtc
    20821 gtactaagct catgctagag gaaattttga ctgatattta caaagcagac tcagaatgga
    20881 atgttgtctt gcttcgttac tttaacccaa tcggagccca tgagagtggt gatttgggag
    20941 aaaatccaaa cggtattcca aacaatctct tgccatatgt gactcaagta gccgttggaa
    21001 aattagagca agtgcaagtg tttggagacg attacgatac ggaagatgga acaggtgttc
    21061 gtgactatat ccacgttgtc gatttggcta agggtcacgt tgcagctttg aaaaaaatcc
    21121 aaaaaggttc aggactaaac gtttataacc ttggaactgg taaaggttac tcagttcttg
    21181 aaattatcca aaacatggaa aaagcggtgg gacgtcctat tccttaccgt atcgtagaac
    21241 gtcgcccagg tgatatcgct gcctgctact cagacccagc aaaagctaaa gcagaactcg
    21301 gttgggaagc agaactcgac atcacccaaa tgtgtgaaga cgcatggcgt tggcaaagca
    21361 agcatccaaa tggatttgaa gactaagatg atgatttcaa tcatcgtccc ttgtttaaac
    21421 gaagaggaag tacttcctct tttttatcag gctctggaag ctttacttcc agatttggaa
    21481 acagaaatcg agtatgtctt tgtcgatgat ggatcaagtg atgggacctt ggaactctta
    21541 aaggcctatc gggagcaaaa tccggcagtc cattatattt ctttctctcg aaattttggc
    21601 aaagaagcag ccctttatgc aggcttgcaa tatgcgacag gagatttggt ggtggtgatg
    21661 gatgcagacc tccaagatcc tcctagtatg ttgtttgaga tgaaaaatgt actagacaaa
    21721 aatgtagact tggactgcgt tgggacacgg agaactagtc gggagggaga acccttcttt
    21781 cgcagtttct gtgctgttct cttttatcgc ctcatgcaaa aaatcagccc agtggctctg
    21841 ccgtcgggtg tccgtgattt tcgtatgatg agaaggtctg tagtcgatgc cattttaagc
    21901 ttgaccgagt ccaatcgttt ttcaaagggg ctcttcgcct gggtgggttt caaaacctac
    21961 tatttggact atccaaatgt cgaaaggcag gctggcaaga ccagttggag ttttaggaaa
    22021 ctctttttct actccattga agggattatt aatttttcag attttccctt gattatagcc
    22081 tttgtagctg gtctcctatc ttgttttctt tctctgctga tgaccttttt tgttgtggtt
    22141 cggaccctca ttttgggcaa tccgacatct ggttggacct ctctgatggc tgttattctc
    22201 tttcttggag gcattcaact cttgaccatt gggattctcg gcaagtatat cagtaagatt
    22261 tatttagaga ctaaaaaaag accactttat cttatcaaag aaaaaagtga tgataggcta
    22321 aaaaagatag aatttatctg acatagtcac tttttgttat ttgtaattct tttagttcgg
    22381 agtttgggtg atttttaaaa gaattaggga tttgaaatga tttaaaaaat ctatgtagac
    22441 taaatttaaa ttgtagtgac ttaataaata aaaaatttag gagtattatg ttatgctaag
    22501 taaagaggat tatactgaag aaatcgggct aataaagaaa caaaattatg tagaggctga
    22561 attgtatcct atagttgctg atataattaa gccaacttta aaagatagtt tatcaaaaag
    22621 atatgtcttc ggaagacaaa gaaggggttt gggacaaatt tattatggtc taagtaattt
    22681 tcctgatata gttattttag ataagactta tgaaaacaaa tctaggaaaa gtataaaaat
    22741 tgaagaatgg aagaaacttc gaggatgcgt ggaagttaag aatttaaatt atagtttaat
    22801 tacagaggaa aaaatcaaat caaccatatc gaacagtttt gaacatataa ctggagagat
    22861 ggaacaacta actggagaga tgggacaact tattggagac cttttatggt ataaaaaagt
    22921 aatttataca aatggaattg aatggagatt tctaagttta gatgacaagg aagagataga
    22981 taatacaatt gttgaagtag ttaacaaaag aatagaaaca gaagaagcgg gaaattcttt
    23041 tgattggtgg aagaatatta aagatttatc gttcaattat acggatatat gcctatctaa
    23101 agattgtaga caagagtgga atgaatttgt aaaaagggta aaggaaatag aatggtagaa
    23161 gtctattctc attgagaaat ttagatttta agttacagta agatttattt agagactaaa
    23221 aaaagaccac tttatcttat caaagaaaaa agtgaccttc ctgattttac agaaaaaaat
    23281 aaagtgaaaa gactataatt ttacatggaa atgtgctaaa ctagagggag tggattatcg
    23341 ccattgattt aggcttcctg gtttccaatc agggcgcgag ttgggcaatt tttaacagcc
    23401 tctaagacat cctgactagg agaaatttct ttttccagtt ggtcagggtc atcgtaaaaa
    23461 cgcacgattc cattatcgtg gtaatcaaat aaatcagaat aagtttggca aagcccacag
    23521 gcgatacatc gttcaggtat aagtgtgatt ttcatgttca tatttatatt gtaataagaa
    23581 aagtaaaaaa aaacaaggag taaggtatgg caaaagaacc gtggcaagaa gatatctatg
    23641 atcaagaaga atcaagagca gagcgtcggc atcgaaacca cggaggggct gataggatgg
    23701 ctaatcgtat tttgacgatc ctagctagta ttttctttgt aattgtggtg gtgatggtca
    23761 tcgttctcat ctatctatca tcggggggaa gtaatcgcac agcagcctta aaagactttc
    23821 atgattctga tgcaagtgta gtacaaatct catcttcaag cagttctcag cctgagcaga
    23881 gttcagagcc agaatctact tctagtagtt cagaagaagc tgctaatcct gaaggaacga
    23941 ttaaagttct cgcaggagaa ggggaagcag ctattgccgc tcgtgcagga atctccattg
    24001 ctcagttaga ggccttgaat cctgggcaca tggctacagg atcttggttt gctaatccag
    24061 gtgatgttat aaaaataaaa taggagccga tatgaaaaca attcaaattg ctattgatgg
    24121 tcctgcttcc agcggtaaga gtacggtcgc aaagattatt gctaaggatt ttggattcac
    24181 ctaccttgat acaggagcta tgtatcgtgc agcgacctat atggctctta agaaccaatt
    24241 aggagttgaa gaagtcgaag cccttctagc cttgttggac cagcatccaa tcagctttgg
    24301 acgttcagaa actggagacc agcttgtttt tgtaggagat gtggatatta cccatcctat
    24361 ccgtgaaaat gaagtgacca atcatgtttc tgctattgca gcaattcctg aagtgcgtga
    24421 gaaactggtt tctctccaac aagaaattgc ccagcaaggc gggattgtca tggatggtcg
    24481 cgatattgga actgttgtat tgccacaagc agaattgaaa attttcctag tagcttctgt
    24541 tgatgagaga gcagagcgtc gttacaagga aaatattgcc aagggaattg aaacagactt
    24601 tgaaacccta aaaaaggaaa ttgctgcgcg tgactacaag gatagtcatc gtgagacttc
    24661 tcctctcaaa caagcagagg atgctgtcta ccttgataca actggtttga acattcaaga
    24721 agtagttgaa aaaatcaaag cagaagctga aaaaagaatg taaatgtaga aaagccgata
    24781 gattgatatc ggtttttttc taaatttgtc aaaatgctga ttttagggta taatagttgc
    24841 tgttcgagaa attttgattt tcaaagaata gtgaatgatg ataaggagaa accatgaaca
    24901 atttaccaaa ttgtccaaaa tgtaactcag agtatgtcta cgaagacggt gccctactgg
    24961 tttgcccaga gtgtgctcat gagtggaatc ctgctgaagt tgcagaagta gaagaaggtc
    25021 ttgtcgctat cgatgccaac ggaaataaat tggctgatgg tgatacagta actctcatca
    25081 aggacttgaa agtaaaaggt gcgccaaaag atttgaaaca agggacgcgc gtgaaaaata
    25141 tccgcatcgt agaaggcgac cacaatatcg actgtaagat tgatggtttt ggtgccatga
    25201 aacttaaatc agagtttgtg aggaagattt aagcatgtca aaacactata aacttgtatt
    25261 ttatagccgt atcttcttgt ttctagcggc ttttacggga gtttatcttg aaattactaa
    25321 gcatggtggt tttgggatgc ttctctatta cacggttctg tccaacctct tggtaactat
    25381 ttttaccctt tatcttctaa aggttatgag ccgtgtaggt gaaaattggc aaaggccaag
    25441 tctcttgcgc ttaaaaggtg gggtcaccat gagtatcatg attacctgtg tgatttacca
    25501 tttcctcttg gcgcccattg cgactaattt ctatacccta gaaaatttcc tttgccacta
    25561 tatcgttccc atctggtttt tagcggatac cctctttttt gacaaacagg gtcaatacaa
    25621 gatttgggat ccagcagtgt ggaccatttt accctttctg tatatgatgt ttgctctttt
    25681 taatggcttg gttctaaaac tcaatattcc aaatgccaag gataatcctt tcccttactt
    25741 ctttttgaat gtgaacaagg gttggaatgt tgtgtttaag tggtgtctga ttatctttgt
    25801 tgcctatatg gtagcaggat ttattttcta ctttatcaag caaatcaaga gaaagtcatc
    25861 ctaatactct tcgaaaatct cttcaaacca cgtcagtttc catctgcaac ctcaaaacac
    25921 tgttttgaac aacctgcggc tagcttccta gtttgctctt tgattttcat tgagtataag
    25981 atacaaggga ttcattttcg aatttaagaa ggagtctaca aaccaatgag gcttcttctt
    26041 ttcttgctta tttgataact atcaaaaaag tagaagatta agagaaatat agaaagagat
    26101 ttcatgaaac aatttttaga acgggccagc attttggctc tctccctcgt tttgattacc
    26161 tccttttcca tttcgagtgc cctaccagcc atgtttgact attatcaggg ttattctaag
    26221 gaacaaattg agctcttggt gagcttgcct tcctttggaa tcatgatgat gttactgcta
    26281 aatggtttct tagaaaaaat atttcctgag cgcttacaga ttagtttggg cttgctgatt
    26341 ttatcattga gcggtacagc tcccttctgg taccaagcct atccctttgt ctttggaaca
    26401 cggcttctct ttggtttggg tcttgggatg atcaatgcca aggccatttc tattatcagt
    26461 gaacgctacc aaggaaaaag gcgaattcag atgttagggc tacgcgcttc tgcagaggtc
    26521 gttggagctt ctctcattac cttggccgtc ggtcagttgt tggcctttgg ttggacagct
    26581 atctttctag cctatagtgc tggatttttg gtgctgcccc tttatctgct ctttgtccct
    26641 tatggaaaat caaagaaaga agtcaagaaa agagcgaagg aagcaagtcg tttaactcga
    26701 gaaatgaaag gcttgatttt taccttagct atcgaagcgg cagttgtagt ttgtaccaat
    26761 acagctatta ccatccgtat tccaagtttg atggtggaaa gaggattggg ggatgcccag
    26821 ttatctagtt ttgttcttag tatcatgcag ttgatcggga ttgtggctgg ggtgagtttt
    26881 tctttcttga tttctatctt taaagagaaa ctgctcctct ggtctggtat tacctttggc
    26941 ttggggcaaa tcgtgattgc cttgtcttca tccttgtggg tggtagtagc aggaagtgtt
    27001 ctggctggat ttgcctatag tgtagtcttg acgacggtct ttcaacttgt ctctgaacga
    27061 attccagcta aactcctcaa tcaagcaact tcatttgctg tattaggctg tagtttcgga
    27121 gcctttacga ccccatttgt tctaggtgca attggcttac taactcacaa tgggatgttg
    27181 gtctttagta tcttaggagg ttggttgatt gtaatctcta tctttgtcat gtacctactt
    27241 cagaagagag cttaggattg attcctaagt ttttcttttg atactcaatg aaaatcaaag
    27301 agcatagttg attgagtttg gaatagtacg ctgtagctgc taaaatattt ctagaaatta
    27361 atttgacttt tctaatagag ttattcatat cttatttcaa tctactatag aaagctagcc
    27421 gcaggttgct caaaatagtg ttttgaggtt gcagatggaa actgacgtgg tttgaagaga
    27481 ttttcgaaga gtatgagatt tttataccca tacaatattt gttttaggtc cttgtttaca
    27541 gactaatttc ttgataaaat agaggttatg acgagatata aagcaactat ttcctatgat
    27601 ggttatgcct ttgctggctt tcagcgccag cctcatgcgc gtagcgttca ggaagaaatt
    27661 gaaaaaacct tgaccagatt aaataaaggg caagccatta ctgttcacgg tgctggtagg
    27721 acagatagtg gggttcatgc cctgggacag gtcattcatt ttgacctgcc ttatcagatg
    27781 gatgaggaga aactccgttt tgccttggat acccagtctc ctgaagatat tgatgtgatt
    27841 tcgattgagc ttgtggcaga tgattttcat tgccgttatg ccaagcatag caagacctat
    27901 gagtttactg tggatagagg acgtcccaaa aatccgatgc gccgtcacta tgccacccac
    27961 tttccctacc cactcgatgt ggaacgaatg cagattgcaa tcaaaaagct agagggaacc
    28021 catgatttta ccggttttac agcctctggg actagtgtag aggataaggt tcgcaccatc
    28081 acagaagcta gtttaatagt cgatgagaca ggacaatttt tgacctttac cttttcagga
    28141 aatggtttct tgtataaaca gattcgcaat atggtgggga ctcttctcaa aatcggtaac
    28201 aaccgcatgc cagtagagca gattgatctc atcttggaga agaaggacag gcaacttgca
    28261 ggtcccactg cagcaccaaa tggtttgtat ttaaaggaga ttcgttatga agaataatcg
    28321 tattttagca ctttctggaa atgatatttt tagtggtggt ggactgtcag ctgatttggc
    28381 tacctatacc ttgaacggct tgcatgggtt tgtagcagtg acttgtttga cagccttgac
    28441 agaaaaagga tttgaagtct ttccaactga tgataccatt tttcaacatg aattagatag
    28501 cttgcgtgat gtggaatttg ggggaattaa gattggtctt ctccctactg tcagtgtggc
    28561 tgagaaggcc ttggacttta tcaaacaacg cccaggagta cctgtggtgt tggatcctgt
    28621 cttggtctgc aaggaaacgc atgatgtagc tgtcagtgag ctctgccaag agttgattcg
    28681 ctttttccct tatgtcagtg tgattacgcc taatctccca gaagcagaat tattatccgg
    28741 tcaggaaatt aaaaccttgg aagacatgaa aactgcagcg cagaaattgc atgatttagg
    28801 agcgccagca gtcattatca agggaggcaa tcgtcttagt caggacaagg ctgtggatgt
    28861 cttttatgat ggacagacct ttactatcct agaaaatcca gttatccaag gccaaaatgc
    28921 tggtgcaggt tgtacctttg cctctagcat tgccagtcac ttgattaaag gtgataaact
    28981 tttgccagca gtagaaagct ctaaggcttt cgtttatcgt gctattgcac aagcagatca
    29041 gtatggagta agacaatatg aagcaaacaa aaacaactaa aatcgccctt gtatccctat
    29101 taaccgccct ttctgtggtt ctaggttatt tcttaaaaat cccaacacct acaggaattc
    29161 taactctttt agatgctggt gtcttctttg cggcctttta ctttggtagt cgtgaaggag
    29221 cggtagtcgg aggactagca agtttcttga ttgacctctt atcaggctac cctcagtgga
    29281 tgttctttag cttggtcaac catggcttgc agggattttt cgcaggattt aaaggaaaaa
    29341 gtcagtggtt aggccttatt ttagcaacta ttgccatggt aggaggctac gccttgggtt
    29401 ctactttgat gaatggctgg gcagcagccc tcccagaaat tctaccaaat ttcatgcaaa
    29461 atatggtagg gatgattgta ggatttattc ttagtcaaag tatcaagaag attaagtaat
    29521 actcttcgaa aatctcttca aaccacgtca gcttccatct gcaacctcaa aacactgttt
    29581 tgagcagcct gaggctagct ttctagtttg cactttgatt ttcattgagt ataaagaggt
    29641 tgagtaaaaa gtatttcaaa taagaaaaac gcatagtatc aggtgttgaa tgaactgccc
    29701 cccaaaaagt tagacagaaa aaatctaact ttttggggtg tttttattat gaaattaa
//
LOCUS       DAVAZT010000025        28779 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVAZT010000025 DAVAZT010000000
VERSION     DAVAZT010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28779
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.025"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(1..405)
                     /locus_tag="VQT45_001042"
                     /pseudo
     CDS             complement(1..405)
                     /locus_tag="VQT45_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            751..1704
                     /locus_tag="VQT45_001043"
     CDS             751..1704
                     /locus_tag="VQT45_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2359377.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLISLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            1755..2945
                     /locus_tag="VQT45_001044"
     CDS             1755..2945
                     /locus_tag="VQT45_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HET2359378.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGTDAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            3094..3465
                     /gene="rnpA"
                     /locus_tag="VQT45_001045"
     CDS             3094..3465
                     /gene="rnpA"
                     /locus_tag="VQT45_001045"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HET2359379.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            3440..4264
                     /locus_tag="VQT45_001046"
     CDS             3440..4264
                     /locus_tag="VQT45_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET2359380.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAKIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            4283..5269
                     /locus_tag="VQT45_001047"
     CDS             4283..5269
                     /locus_tag="VQT45_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HET2359381.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSKTFYVTINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            5320..5943
                     /locus_tag="VQT45_001048"
     CDS             5320..5943
                     /locus_tag="VQT45_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HET2359382.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPGWQLQQTSQWMNQAQRLRPHFWVYLQRDEQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            6074..7531
                     /locus_tag="VQT45_001049"
     CDS             6074..7531
                     /locus_tag="VQT45_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET2359383.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            7554..7835
                     /locus_tag="VQT45_001050"
     CDS             7554..7835
                     /locus_tag="VQT45_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2359384.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            7912..8397
                     /locus_tag="VQT45_001051"
     CDS             7912..8397
                     /locus_tag="VQT45_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2359385.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            8414..9079
                     /locus_tag="VQT45_001052"
     CDS             8414..9079
                     /locus_tag="VQT45_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HET2359386.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            9083..9946
                     /locus_tag="VQT45_001053"
     CDS             9083..9946
                     /locus_tag="VQT45_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HET2359387.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SRGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            9948..10652
                     /locus_tag="VQT45_001054"
     CDS             9948..10652
                     /locus_tag="VQT45_001054"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HET2359388.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVAWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            10831..12504
                     /locus_tag="VQT45_001055"
     CDS             10831..12504
                     /locus_tag="VQT45_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET2359389.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            12616..13707
                     /gene="ulaG"
                     /locus_tag="VQT45_001056"
     CDS             12616..13707
                     /gene="ulaG"
                     /locus_tag="VQT45_001056"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HET2359390.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            13821..15797
                     /gene="tkt"
                     /locus_tag="VQT45_001057"
     CDS             13821..15797
                     /gene="tkt"
                     /locus_tag="VQT45_001057"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET2359391.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVTDYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            15914..16213
                     /gene="yajC"
                     /locus_tag="VQT45_001058"
     CDS             15914..16213
                     /gene="yajC"
                     /locus_tag="VQT45_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET2359392.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVEGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            16260..16688
                     /locus_tag="VQT45_001059"
     CDS             16260..16688
                     /locus_tag="VQT45_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HET2359393.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            16690..17100
                     /locus_tag="VQT45_001060"
     CDS             16690..17100
                     /locus_tag="VQT45_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359394.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            17400..20051
                     /gene="adhE"
                     /locus_tag="VQT45_001061"
                     /gene_synonym="adhC"
     CDS             17400..20051
                     /gene="adhE"
                     /locus_tag="VQT45_001061"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HET2359395.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITEPSMEATSALMNHEGIATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(21036..21344)
                     /locus_tag="VQT45_001062"
     CDS             complement(21036..21344)
                     /locus_tag="VQT45_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2359396.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(21341..21649)
                     /locus_tag="VQT45_001063"
     CDS             complement(21341..21649)
                     /locus_tag="VQT45_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2359397.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(21654..22949)
                     /locus_tag="VQT45_001064"
     CDS             complement(21654..22949)
                     /locus_tag="VQT45_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2359398.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTKFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPSAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGIVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(22967..24376)
                     /locus_tag="VQT45_001065"
     CDS             complement(22967..24376)
                     /locus_tag="VQT45_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET2359399.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTEDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSLCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            24534..25262
                     /locus_tag="VQT45_001066"
     CDS             24534..25262
                     /locus_tag="VQT45_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2359400.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            25722..25916
                     /locus_tag="VQT45_001067"
     CDS             25722..25916
                     /locus_tag="VQT45_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2359401.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSDVTLITGKNGTGKSTLL"
     gene            complement(26282..27592)
                     /locus_tag="VQT45_001068"
     CDS             complement(26282..27592)
                     /locus_tag="VQT45_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HET2359402.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNFAITNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYRKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTSIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            27829..28701
                     /locus_tag="VQT45_001069"
     CDS             27829..28701
                     /locus_tag="VQT45_001069"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HET2359403.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAILLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT         9002 a         5135 c         5988 g         8654 t
ORIGIN      
        1 catttctttt taccagaatc attcgctaat tcttttttta gggcgattga tttgtacttc
       61 cgtcgcatca atcattaccg tgtcctcaga actgagagga gttcttgaaa tcgtaacacc
      121 actttgaaca agagttactt caacccattg gctccgacgg attaagttgc tttcgtggat
      181 accaaaatca gccgcaattt cttcataagt gcggtattct cgcacatatt gaagagtgcc
      241 cataagaagg tcttctaggc ttaatttagg ttttcgtcca ccttttgcgt gtttaagttg
      301 ataagctgtt tttaatacag ctaacatctc tttaaaagtc gtgcgctgaa caccaacaag
      361 acgcttaaat tgtgcattgg ttagttgttt actttcttca taaattttat tgtatcatat
      421 ttttgtttca caggaagtct aataaataaa aattctttaa aattttgttg ggaaaatggg
      481 aaaagatata aatggaaact tagtataaca cttggaaaac tctgtaaaaa tagtaagtca
      541 attcatgtcc cgttttttct ctagggaagt tgggcggcta tatttatatg accatttgtc
      601 gtaataaaca tccctaccaa gggtcaatag aaataaattc aacgaaactt ttgctgtcag
      661 atttagatgc ccaatttgtc atttatactc tttcatatag gactttctat aaggatggaa
      721 aaaagaaggg aaatttgata agataggaat atggattttg aaaaaattga acaagcttat
      781 acctatttac tagagaatgt ccaagtcatc caaagtgatt tggcgaccaa cttttatgac
      841 gccttggtgg agcaaaacag catctatctg gatggtgaaa ctgagctaaa ccaggtcaaa
      901 gacaacaatc aggcccttaa gcgtttagca ctacgcaaag aagaatggct caagacctac
      961 cagtttctct tgatgaaggc tgggcaaaca gaacccttgc aggccaatca ccagtttaca
     1021 ccggatgcta ttgctttgct tttggtgttt attgtggaag agttgtttaa agaggaggaa
     1081 attactatcc tcgaaatggg ttctgggatg ggaattctag gcgctacttt cttgatctcg
     1141 cttgataaaa aggtggatta cttgggaatg gaagtggatg atttgctgat tgatctggca
     1201 gctagcatgg cagatgtaat tggtttgcag gctggctttg tccaaggaga tgccgttcgt
     1261 ccacaaatgc tcaaagaaag cgatgtggtc atcagtgact tgcctgttgg ctattatcct
     1321 gatgatgccg ttgcgtcgcg ccatcaagtt gcttctagcc aagaacatac ttacgcccat
     1381 cacttgctca tggaacaagg gcttaagtac ctcaagtcag acggatacgc tatttttcta
     1441 gctccgagtg atttgttgac cagtcctcaa agtgatttgt taaaagaatg gctgaaagaa
     1501 gaggcgagtc tggttgctat gattagtctg cctgaaaatc tctttgctaa tgctaaacaa
     1561 tctaagacta tttttatcct acagaagaaa agtgaaatag cagtggagcc ttttgtttat
     1621 ccacttgcta gcttgcaaga tgcaagtgtt ttaatgaaat ttaaagaaaa ttttcaaaaa
     1681 tggactcaag gtactgaaat ataaaataga ttttgttata atagttgaaa acgcttaaaa
     1741 aggggtatca tgttatgaca aaaacaattg caatcaatgc aggaagttca agtttgaaat
     1801 ggcaattata cttaatgcca gaggaaaaag tgttagccaa aggtttgatt gaacgtatcg
     1861 gtttgaaaga ttcaatttca actgtaaaat ttgacggccg ttctgaacaa caaattttgg
     1921 atatcgaaaa tcatacacaa gctgttaaaa ttttattgga tgacttgatt cgtttcgata
     1981 ttatcaaggc ttatgacgag attacaggtg ttggccaccg tgttgtagca ggtggagaat
     2041 atttcaaaga atcaacagtt gttgagggag atgttttaga aaaagttgaa gagttgagtt
     2101 tgttggctcc tctacacaac ccggccaatg cagcaggtgt tcgtgctttc aaggaattgt
     2161 tgccagacat taccagtgta gttgtttttg atacttcctt ccacacaagt atgccagaga
     2221 aagcttatcg ctaccctcta ccaacaaaat attacacaga aaacaaggtt cgtaaatacg
     2281 gtgctcatgg tacaagtcac cagtttgtag caggagaagc tgcaaaactc ttgggacgtc
     2341 cattagaaga cttgaagtta attacctgtc atattggtaa cggaggctca attacagctg
     2401 tgaaagccgg caaatctgta gacacttcta tggggttcac tcctcttggt ggtattatga
     2461 tgggaacgcg tacaggggat attgatccag ctatcattcc ttatttaatg caatatacag
     2521 aggattttaa cacaccagaa gatatcagtc gtgttcttaa ccgtgaatca ggtcttttgg
     2581 gagtttctgc taattctagc gatatgcgcg atatagaagc agctgtagca gaagggaatc
     2641 acgaggctag cttggcttat gaaatgtatg ttgaccgtat ccaaaaacat atcggtcagt
     2701 accttgcagt gctaaatgga acagatgcca ttgttttcac agcaggtgtc ggtgaaaatg
     2761 cagagaattt ccgtcgtgat gtaatctcag ggatttcgtg gtttggttgt gatgttgatg
     2821 atgaaaagaa tgtctttggc gttacaggag acatctcaac agaggcagct aaaatccgtg
     2881 tcttggttat tccaacagat gaagaattag tcattgcccg tgacgttgaa cgcttgaaaa
     2941 aataagtgaa actaaaaaaa tattcaatac aaggagttgg gaaagttatt tttccagctt
     3001 ctttttctga tgaaattgtc caaaaccttg ctatgattgg cttttttgaa aaatatggta
     3061 taatagtagt aatttaatag atggagttga gttttgaaga aaaactttcg tgtaaaaaga
     3121 gagaaagatt ttaaggcgat tttcaaggag gggacaagtt ttgctaatcg caaatttgtg
     3181 gtctaccaat tagaaaacca gaaaaaccat tttcgagtag gtctatcagt tagcaaaaaa
     3241 ctggggaatg ccgtcactag aaatcaaatt aagcgacgga ttcggcatat tatccagaat
     3301 gcaaaaggga gtctggtaga agatgtcgac tttgttgtca ttgctcgaaa aggagtcgaa
     3361 accttgggat acgcagagat ggagaaaaat ctactccatg tattaaaatt atcaaagatt
     3421 taccgggaag gaaatgggag tgaaaaagaa actaaagttg actagtttgc taggactgtc
     3481 tctgttaatc atgacagcct gtgcgactaa tggggtaact agcgatatta cagccgaatc
     3541 ggctgatttt tggagtaaat tggtttactt ctttgcgaaa atcattcgct ttttatcgtt
     3601 tgatattagt atcggagtgg ggattattct ctttacggtc ttgattcgta cagtcctctt
     3661 gccagtcttt caggtgcaaa tggtggcttc taggaaaatg caggaagctc agccacgcat
     3721 taaggcgctt cgagaacaat atccaggtcg agatatggaa agcagaacca aactagagca
     3781 ggaaatgcgt aaagtattta aagaaatggg tgtcagacag tcagattctc tttggccgat
     3841 tttgattcag atgccggtta ttttggcctt gttccaagcc ctatcaagag ttgacttttt
     3901 aaagacaggt catttcttat ggattaacct tggtagtgtg gatacaaccc ttgttcttcc
     3961 gattttagca gcagtattca cctttttaag tacttggttg tccaacaaag ctttgtctga
     4021 gcgaaatggc gctacgactg cgatgatgta tgggattcca gtcttgattt ttatctttgc
     4081 agtttatgcg ccaggtggag tcgccctata ctggacagtg tctaatgctt atcaagtctt
     4141 gcaaacctat ttcttgaata atccattcaa gattatcgca gagcgcgagg ccgtagtaca
     4201 ggcacaaaaa gatttggaaa atagaaaaag aaaagccaag aaaaaggctc agaaaacgaa
     4261 ataaataagg aggaatctgg taatggtagt atttacaggt tcaactgttg aagaagcaat
     4321 ccagaaagga ttgaaagaat tagatattcc aagaatgaag gctcatatca aagtcatttc
     4381 tagggagaaa aaaggctttc ttggtctatt tggtaaaaaa ccagcccaag tggatattga
     4441 agcgattagt gaaacgactg ttgtcaaagc aaatcaacag gtagtaaaag gcgttccgaa
     4501 aaaaatcaat gatttgaacg agcctgtgaa gacggttagt gaagaaaccg ttgaccttgg
     4561 tcatgtggtt gatgctatta aaaaaataga ggaagaaggt caaggtattt ctgatgaagt
     4621 caaggctgaa atcttaaaac atgaaagaca tgccagcact atcttagaag aaactggtca
     4681 cattgagatt ttaaatgaac ttcaaatcga ggaagcgatg agggaagaag caggcgctga
     4741 tgaccttgaa actgagcaag atcaaactga aaatcaagac ttgaaagaga tgggcttgaa
     4801 ggtcgagcaa agttatgata ttgcccaggt ggctacggat gtgactgcct atgttcaagc
     4861 gattgtggat gacatggatg ttgaagctac actttcaaat gattataacc gtcgtagcat
     4921 caatctacaa attgacacca acgaaccagg tcgtattatc ggctaccatg gtaaagtctt
     4981 gaaggccttg caactgttgg ctcaaaatta tctttacaac cgctattcca aaaccttcta
     5041 cgttacaatc aatgtcaatg attatgtcga acaccgtgca gaagtcttgc agacctatgc
     5101 gcaaaaattg gcgattcgtg ttttagaaga aggacgtagt catcaaacag atccaatgtc
     5161 gaatagtgaa cgcaagatta tccaccgtat tatttcacgt atggatggcg tgaccagtta
     5221 ctctgaaggt gatgagccaa atcgctatgt cgttgtagat acagaataag taaaatcagg
     5281 gttgacctga ttttttgcta gctagaggag gttaaactaa tgttgaataa gataagagac
     5341 tatttagact ttgctggttt gcagtaccgt aatcctgata aagcgggagc agagcgagag
     5401 aagatgctgg cattccgcca caaaggacaa gaggcccgaa aggcttttac agaactggcc
     5461 aaagcctttc aagcaagcca tccaggatgg caactccaac agactagtca gtggatgaat
     5521 caggcccagc gtttgagacc acatttttgg gtttatctac agagagacga acaagtgaca
     5581 gaacctatga tggccttacg tttgtatggg acatctactg actttggaat ttctttggaa
     5641 gtcagtttca tcgaacgtaa gaaggatgag caaacactgg gcaagcaggc caaagtttta
     5701 gacattccaa ccgttaaagg gatttattat ctaacctact ctaatggtca aagtcaacgg
     5761 tgggaggcga atgaagaaaa gcgtcgtact ttacgcgaga aggtgagaag tcaagaagtt
     5821 cgaaaagttt tagtgaaggt agatgttcct atgacagaaa attcgtctga agaagaaatc
     5881 gtagaaggct tattgaagtc ttattctaaa attcttccct attatctagc tacgagaaaa
     5941 taagataatt tgtaaaacat cataaatcat acagtccaag agtgaacagt ccgctgtgta
     6001 attcttggtc tttttgtttg cgctttcgca ttatataata aacttacaaa aacaattcaa
     6061 aaggagaaca attatggaag tcgtttcaag tgttctaaat tggttttcta gcaatatttt
     6121 gcagaatccc gcatttttcg taggtttatt ggtgttgata ggatatgcac ttttgaaaaa
     6181 acctgcccat gacgtttttt cagggtttgt taaagcaaca gtagggtata tgttgcttaa
     6241 cgtgggtgct ggtggtttgg ttacaacctt tcgtccaatc ttagcagctc ttaactacaa
     6301 attccaaatt ggtgcagcgg ttatcgaccc ttactttgga cttgctgcag caaacaacaa
     6361 aattgcagca gagtttccag attttgttgg aactgcaact acagctctat tgattggttt
     6421 tggaataaat atcttgctcg tagctcttcg aaagattacg aaggtaagaa ccctctttat
     6481 tactggtcac atcatggtac aacaagctgc aacagtatct cttatggttc tattcttagt
     6541 accacaattg cgcaatgctt acggtacagc agcgattggt atcatctgtg gactttactg
     6601 ggcagttagt tcaaatatga ctgttgaggc aactcaacgc ttgactggtg gtggcggatt
     6661 tgcgattggt caccaacagc aatttgcaat ctggtttgta gataaagtag caggacgctt
     6721 tggtaagaaa gaagaaagtt tagacaatct taaattacct aagttcctct caatcttcca
     6781 cgatacagtt gttgcatctg ctaccttgat gctcgtattc ttcggagcca ttcttttaat
     6841 cttgggtcca gacattatgt ctaataaaga agtcatcact tcaggaactc tattcaatcc
     6901 tgctaaacaa gatttcttta tgtacattat ccaaacagcc tttaccttct cagtttactt
     6961 gttcgttttg atgcaaggtg tccgaatgtt cgtatctgag ttgacaaacg ccttccaagg
     7021 tatttcaaac aaattgttgc caggttcatt cccagcggtt gacgttgcag cttcttatgg
     7081 atttggttct ccaaatgctg tcttgtcagg atttaccttt ggtttgattg gtcaattgat
     7141 tacaattgtt ttgctcatcg tctttaaaaa tccgattctt attattacag gatttgtacc
     7201 agtgttcttt gacaatgcag ccattgcggt ctacgctgat aaacgcggcg gatggaaagc
     7261 ggctgttatc ctttccttta tatcaggtgt ccttcaagtt gctctaggag ctctttgtgt
     7321 ggcccttctc gatttggcat cttatggtgg ctaccatgga aatatcgact ttgaattccc
     7381 atggcttgga tttggatata tcttcaaata ccttggtatt gttggttatg tacttgtgtg
     7441 tctcttcttg cttgttattc ctcaacttca atttgccaaa gcaaaagata aagagaaata
     7501 ttacaacggt gaagttcaag aagaagctta gtatctagaa aaggagaaat aaaatggtta
     7561 aagtattagc agcgtgcgga aatggaatgg gttcatcaat ggttatcaag atgaaggttg
     7621 aaaatgctct ccgtaagctt aatcaaacag attttacagt caattcatgc agtgtcggtg
     7681 aagctaaagg tttagcagta ggatatgaca ttgtaatcgc ttctcttcat ttgattcaag
     7741 aattggaagg gcgaactaat gggaagttaa ttgggcttga taacttgatg gatgataaag
     7801 aaatcaccga aaaactcagt caagcactac agtaaaaggt tggagggggc tggacagaaa
     7861 ctgagagtta tcgtttctgt ccagccccct ctttaaataa aggaggcaga tatgaattta
     7921 aaacaagctt taattgacaa tgactcgatc cgactaggtt tagaggctaa caattggaaa
     7981 gaagcagtca aggtagcagt agatcccttg attgaaagtg gggcaatttt gccagagtat
     8041 tacgatgcta tcattgaatc gactgaagag tatgggcctt actatatctt gatgccaggt
     8101 atggctatgc cccacgctag acctgaagct ggtgtgcaaa gtgatgcctt ttcattgatt
     8161 accttacaaa atcctgttgt attttcagat gggaaagagg tatctgtttt gttggcacta
     8221 gcagcaacaa gttcaaaaat tcacacaagt gtagccattc cacaaattat tgccctgttt
     8281 gaattagaag attctattgc acgtttacag gcttgccaga ctaaagaaga tgtcttggct
     8341 atgattgaag aatctaagga tagcccttat ctcgaaggat tggatttgga aagttagaaa
     8401 gaggaataaa gaaatgacaa aaagaatacc taatttacaa gttgcattag accattcaga
     8461 cttgcaagga gcgattaaag cagctgtttc tgttggtcag gaagtagata ttatcgaagc
     8521 tggaactgtt tgcttgcttc aagttggaag tgaactggct gaagtcttgc gtagcctttt
     8581 cccagataag attattgtgg cagacacaaa atgtgctgat gctggtggaa cagttgctaa
     8641 aaataatgcg gttcgtggag cagactggat gacttgtatc tgttgtgcaa ccatccctac
     8701 tatggaagca gctctaaagg ctatcaagac tgaacgagga gaacgaggcg aaatccagat
     8761 cgagctttat ggcgattgga cttttgaaca agctcagctt tggctagatg caggtatctc
     8821 acaagctatt tatcaccaat ctcgtgatgc tcttcttgct ggtgaaactt ggggtgaaaa
     8881 agaccttaat aaggttaaaa aactcattga catgggcttc cgtgtatctg taacaggtgg
     8941 tctagatgta gatactctca aactctttga aggtgttgat gtctttacct ttatcgcagg
     9001 tcgtggaatt acagaggctg cggatccagc aggagcagcg cgtgccttca aggatgaaat
     9061 caaacgaatt tgggggtaaa tcatggtacg tccaattgga atttatgaaa aggcaacccc
     9121 aacacacttt acttggctag aacgtttaaa ttttgccaag gagttaggct ttgattttgt
     9181 cgagatgtct attgacgaac gtgacgagcg tttagcaaga cttgactgga gtaaggaaga
     9241 acgcttggaa gttgtcaaag aaatctatga aactggtgtt cgtattcctt ctatctgttt
     9301 ttcaggccat cgtcgctacc cattgggttc aaaagatcca gttctagagg aaaaatctct
     9361 agaactcatg aaaaaatgta tcgaattagc tcaagacttg ggagttcgta cgattcaatt
     9421 agctggttac gatgtttact atgaggaaaa gtcaccccag acacgccaac gttttatcaa
     9481 aaatttgaga aaagcctgtg actgggctga agaagctcag gtggtacttg ctattgaaat
     9541 tatggatgat cctttcatca atagcatcga aaaatatttg gctatagaaa aagagattga
     9601 ctctcccttc ctctttgtat atccagatat tggtaatgtg tctgcatggc ataatgatat
     9661 ctatagtgag ttttatcttg gtcatcatgc catcgcagct ctccatctca aggatactta
     9721 tgcagtgaca gaaagttcaa ggggccagtt ccgagatgta ccttttgggc aaggttgtgt
     9781 caaatgggaa gaagctttcg atattttaaa ggaaaccaat tataatggac ctttcctaat
     9841 cgaaatgtgg tctgaaaatt gtgaaacagt agaagaaaca cgcgcagcca ttcaagaggc
     9901 gcaagctttt ctctatccac tcattaagaa agcaggtttg atgtaagatg aatcaagtaa
     9961 tcaatgctat gcgtaaacga gtctgtgatg ccaatcaatc attgccaaaa catggacttg
    10021 tcaaatttac ctgggggaat gtatctgaag tcaatcgcga actcggtgtc attgttatca
    10081 aaccatcagg cgtggattat gacgaattga cacctgaaaa catggtagtg actgatctag
    10141 atggtaagat cctagaaggg gatttaagac catcttccga cctcccaact catgtgcaat
    10201 tatataaggc ttggtcagaa attggtagtg tggttcacac ccattcgaca gaagctgttg
    10261 cttgggctca ggcaggtcgt gatattcctt tctacggaac aacccatgca gattatttct
    10321 acggttcaat cccttgcgcc cgtagtttga ccaaggacga agtagaagtg gcctatgaaa
    10381 aagatactgg cctggttatc gtagaagagt ttgaacatcg cggacttaac ccggttgaag
    10441 taccaggaat tgttgtacgc aatcacggtc cattcacctg gggcaaaaat ccagagaatg
    10501 ctgtttatca ctctgtcgta ctagaggaag tatcaaagat gaatcgcttt acagaacaaa
    10561 tcaatccaag agttggacct gctccccagt acatactaga aaaacactac caacgtaaac
    10621 atggaccaaa tgcttattat ggtcaaaagt aagaacgatg aaggaggaga aaaagataaa
    10681 tttagctcct ctttttacat ttgattttta ttgagagtaa agttggagtt gaagtaattt
    10741 taaaagattt tttagaaata gcgcttgata tatatatggt aaaataaaaa gaattgctgt
    10801 gatatcaata gatttggggg attttttaat atggtactgg ataaggcaag ttgtgatttg
    10861 cttcaatatt tgatggatca agaaacgtcc aaaacgatta tggcgatttc gaaagatttg
    10921 aaagagtcaa gaaggaaaat ttattatcac attgacaaaa tcaatgctgc tctgggtgac
    10981 gaggcgcttc acatcattag tattccacga attggtattc acttaacgga agagcagaga
    11041 gatgcttgtt gtaaactatt atcggaagta gattcgtacg attatatcat gagtgcgcat
    11101 gaacgtatga tgataatgtt actatggata ggtatttcta aagaacgtat tacgattgaa
    11161 aaattgatag agttaacaga ggtatctagg aatactgttc tcaatgattt gaatagtatt
    11221 cgttatcaac taactttgga acaatatcag gtgatcttgc aagtgagcaa gtcacaggga
    11281 taccaccttc atgcccaccc tcttaataaa attcagtatc ttcaatcgct tctatatcat
    11341 atttttatgg aagaaaatgc cacttttgta tctattttag aagataagat gaaagagagg
    11401 ttagatgatg agtgtttgct ttctgttgaa atgaaccaat tttttaagga acaggttcct
    11461 ttagttgaac aagatttagg gaagaaaata aaccatcatg aaataacttt tatgttgcag
    11521 gttctacctt atttgctgtt aagctgtcat aatgttgaac agtatcaaga aagacatcag
    11581 gatatagaga aagaattttc tttgataaga aaaagaatag agtatcaggt gtctaagaaa
    11641 ttaggagaac ggttgtttca aaagtttgaa atttctttgt caggacttga agtttctctt
    11701 gtagctgttc tcctcctctc ctatcgtaaa gatttggata ttcatgcaga aagtgatgat
    11761 tttcggcaat taaaacttgc tttagaagaa tttatctggt attttgaatc acaaatccga
    11821 atggagattg agaacaagga tgatttgtta cgaaatttga tgatccactg taaagccttg
    11881 ttatttagaa agacttacgg tattttttct aaaaatcctc taacaaaaca aattcgatcc
    11941 aagtatggag aattattttt agtcactaga aaatctgcgg aaattttaga aggagcatgg
    12001 tttattcggc taacagacga tgatattgcc tatttgacga ttcatattgg aggattttta
    12061 aaatatacac catcatctca aaaaaatatg aaaaaagttt atctcgtttg tgatgaaggt
    12121 gttgcggttt cgagactttt gctgaaacaa tgcaaacttt attttccaaa tgagcaaatt
    12181 gacactgtat ttacaacaga acaatttaag agtgtggaag atattgcaca agttgatgta
    12241 gtgattacta ctaatgatga tttggatagc agatttccga ttttaagggt taatcctatc
    12301 cttgaagcag aagatatttt gaaaatgcta gactatctta aacacaatat atttcgtaat
    12361 aagagcaaaa gtttcagtga aaatctttct agtcttattt cgtcttatat tgtagacagc
    12421 aagttggcta gtaagttcca agaagaggtt caaacactta taaatcaaga aatagtagtt
    12481 caagcttttt tggaagatat ttgaaggaca gtccaatgat gaacacaaac ctgtgttttt
    12541 cttggtcttt tttagtgttt tgaagggtgg tatactaatc tcaaagataa caattatatc
    12601 caaaggaggc aacatatgcc aaacgtcaaa gaaattacaa gagagtcatg gattttagcc
    12661 actttcccag agtggggaac atggttgaac gaagaaatcg aagaagaagt cgtacctgaa
    12721 ggcaactttg ccatgtggtg gctaggcaac tgtggtactt ggattaagac accagctggt
    12781 gctaacgttg tcatggacct ttggtcaaac cgtggaaaat caaccaaaaa agtgaaagat
    12841 atggttcgtg ggcaccaaat ggcaaatatg gcaggtgttc gtaagctgca accaaacttg
    12901 cgtgttcagc caatggttat cgatccattt gctatcaacg aactagacta ttacttagtt
    12961 tcacacttcc acagtgatca tatcgaccca tacacagctg cagcaattct caataatcct
    13021 aagttagagc atgttaagtt tatcggtcct taccactgtg gacgaatctg ggaaggatgg
    13081 ggtgttccaa aagaacgtat catcgttgtt aaaccaggtg acactatcga attaaaagat
    13141 atgaagattc atgcagtaga atcatttgac cgtacttgct tggtaactct cccagtgaac
    13201 ggtgctgatg agacaggcgg tgaacttgct ggcttggctg ttacagatga agaaatggct
    13261 caaaaggctg ttaactatat ctttgaaaca ccaggtggaa ccatctatca tggtgcagat
    13321 tctcacttct caaactattt tgcaaaacat ggtaaagact ttaaaattga tgttgctttg
    13381 aataactatg gtgaaaatcc ggtaggtatc caagacaaaa tgacatctat cgaccttctt
    13441 cgtatggcag aaaatctgcg taccaaagtc attatcccag ttcactatga tatctggtct
    13501 aacttcatgg cttctactaa tgagattcta gaactttgga aaatgcgaaa agatcgcttg
    13561 caatacgatt tccatccatt tatctgggaa gttggcggta agtacactta tcctcaagat
    13621 caacacttag tagaatacca tcatccacgt ggttttgatg attgttttga acaagactct
    13681 aacattcaat ttaaagcttt gctataatat aaaaatattc tttggaggtt atccgtatgt
    13741 tgcatgatac ggataatttt catataatag taaaatagaa tgtgtgattc aataatcacc
    13801 tcaaatagaa aggaaattct atgtcaaatc tatctgttaa tgcaattcgt tttctaggta
    13861 ttgacgccat taataaagcc aactcaggtc atccaggtgt ggttatggga gcggctccga
    13921 tggcttacag cctctttaca aaacaacttc atatcaatcc agctcaacca aactggatta
    13981 accgcgaccg ctttattctt tcagcaggtc atggttcaat gctcctttat gctcttcttc
    14041 acctttctgg ttttgaagat gtcagcatgg atgagattaa gagtttccgt caatggggtt
    14101 caaaaacacc aggtcaccca gaatttggtc atacggcagg gattgatgct acgacaggtc
    14161 ctctagggca agggatttca actgctactg gttttgccca agcagaacgt ttcttggcag
    14221 ccaaatataa ccgtgaaggt tacaatatct ttgaccacta tacttacgtt atctgtggag
    14281 acggagactt gatggaaggt gtctcaagcg aggcagcttc atacgcaggc ttgcaaaaac
    14341 ttgataagtt ggttgttctt tatgattcaa atgatatcaa cttggatggt gagacaaagg
    14401 attcctttac agaaagtgtt cgtgaccgtt acaatgccta cggttggcat actgccttgg
    14461 ttgaaaatgg aacagacttg gaagccatcc atgctgctat cgaaacagca aaagcttcag
    14521 gcaagccatc tttgattgaa gtgaagacgg ttattggata cggttctcca aacaaacaag
    14581 gaactaatgc tgtacacggc gcccctcttg gagcagatga aactgcatca actcgtcaag
    14641 ccctcggttg ggactacgaa ccatttgaaa ttccagaaca agtatatgct gatttcaaag
    14701 aacatgttgc agaccgtggc gcatcagctt atcaagcttg gactaaatta gttacagatt
    14761 ataaagaagc tcatccagaa ctggctgcag aagtagaagc catcatcgac ggacgtgatc
    14821 cagtcgaagt gactccagca gacttcccag ctttagaaaa tggtttttct caagcaactc
    14881 gtaattcaag tcaagatgcc ttgaatgttg tggcagctaa attaccaacc tttctaggtg
    14941 gatcagctga ccttgctcac tcaaacatga cttatatcaa gacggatgga cttcaagacg
    15001 atgccaatcg cttgaatcgt aacattcagt ttggtgttcg tgaatttgca atgggaacaa
    15061 tcttgaacgg gatggccctt catggtggac ttcgtgtata cggtggaact ttcttcgtct
    15121 tctctgacta tgtgaaggca gctgtccgct tgtcagcctt acaaggactt cctgtgactt
    15181 atgtctttac ccatgattca atcgcagttg gggaagatgg tccgactcat gaaccagttg
    15241 agcatttagc aggtcttcgt gctatgccaa atctaaatgt tttccgtcca gcagatgcgc
    15301 gtgaaacgca agcagcttgg taccttgcag tgacaagtga gaaaacacca actgcccttg
    15361 tcttgacacg tcaaaatttg actgttgaag atggaacaga cttcgacaag gttgctaaag
    15421 gtgcttatgt tgtatatgaa aatgcagccg actttgatac catcttgatt gcgacaggtt
    15481 cagaggttaa tcttgctgtc tcagctgcta aagaattggc tagtcaaggc gaaaaaatcc
    15541 gcgtagtcag catgccatct acagatgtct ttgataaaca agatgcagct tacaaggaag
    15601 aaattcttcc aaatgcagtc cgccgtcgtg ttgcagtcga aatgggtgca agtcaaaact
    15661 ggtacaaata tgttggtctc gatggtgccg ttctaggtat tgataccttc ggagcctctg
    15721 ccccagcacc aaaagtattg gcagaatatg gctttactgt agaaaatctt gtaaaagttg
    15781 ttcgaaactt gaaataatcc taaaaatcag ggcgtaagct ctggtttttc ttaccagaaa
    15841 agtaaggtac aatcttgtaa aagtagctga aatttgatat agtagtccta tgtaaaagac
    15901 aaaggagaaa acaatgaatc caaatattac ttttttaatc atgcttgtag gtatgatggc
    15961 cttgatgttc tttatgcaac gttctcaaaa gaaacaagct caaaagcgta tggaaagctt
    16021 aaataaacta caaaaaggct atgaagtgat tacaatcggt ggactttatg gaacagtcga
    16081 tgaagtagat acggagaagg gaacaatagt tcttgacgta gagggagttt acttgacttt
    16141 tgaactagct gctatcaaga cagtattacc gctgaaagaa acagcttcac tagaaggcgc
    16201 aattgaaaaa taagacggga tcacgaactc ccgtttttct ataaaagaaa ggaaatggga
    16261 tgaaaaaatt agtctttgtc tgtctgggaa atatttgccg tagccctatg gccgagtttg
    16321 ttatgaaatc aatgacagat aactacgaaa tccaaagtcg agcaacttcc tcttgggaac
    16381 atggcaatcc gattcataag gggactcagg gaatttttca agagtatgag attccttatg
    16441 acaagaacaa gacatcgctt cagattagta aggaagattt tgaagccttt gattatatta
    16501 tcggaatgga cgcttcaaat atttctgact tacgtcagat gtgtccagta gactgtcaag
    16561 ataagattta ctcattttca tctgaaagtg ttccagaccc ttggtataca ggagattttg
    16621 aagaaaccta tcgacgtgtt caagagggct gtcaagcttg gttagaacgt ttagaaaagg
    16681 agagttaagg tggaaaatct tacgaatttt tacgaaaagt atcgtgtcta tctgactcgt
    16741 ccacgtttag agcttttggc agtagttacc attgttttct gtgctgtact cgtctttttt
    16801 ctaaatattc caggaaaagg tgtcttaaaa ctcgataatg gaacgattgt ttatgatggc
    16861 agtcttgtcc gcggtaaaat gaatggccaa ggtaccatta ccttccaaaa tggagaccaa
    16921 tatacaggtg gcttcaacaa tggagccttc aacggaaaag gtacctttca atctaaagaa
    16981 ggctggacct acgaaggtga ttttgtaaat ggtcaggctg aaggaaaagg gaaactaaca
    17041 acagaacaag aagtcgttta tgaaggaact tttaaacaag gcgtttttca acaaaaataa
    17101 agcctcctta tcaaaggagg tattattaga atcgcaaggt aagcgcttac ctgcaaatcc
    17161 ctttctttcc aaatccctct tccaagcaag tttgtgaaat aaaaaatatt tgaaataaat
    17221 ttcacaaact tcaaagataa aacctgataa gaaaagaaaa tgagaaaagt ttcacaagag
    17281 tttaaaaatt ctttgtgaaa tgtttatgaa actgtttaca aagttgaaat aatgcgttat
    17341 aataaacttg tgaaaaaatt aacaaaggat atcgttcctt gaaagctatg gaggaaaata
    17401 tggctgataa aaaaactgtg acaccagagg aaaagaaact cgttgctgaa aaacacgtag
    17461 atgagttggt tcaaaaagct ctagttgccc ttgaagaaat gcgtaaattg gatcaagaac
    17521 aagttgacta catcgttgcc aaagcatcag tagcagcttt ggatgcccac ggagaattgg
    17581 ctttacatgc ctttgaagaa acaggacgtg gtgtatttga agataaagca actaagaact
    17641 tgtttgcttg tgaacacgtg gtaaacaaca tgcgtcacac taaaacagtt ggcgttatcg
    17701 aagaagatga tgtaacagga ttgaccctga ttgctgaacc agttggtgtt gtttgtggta
    17761 tcactccaac aacaaaccca acatcaacag cgatcttcaa atcattgatt tcattgaaga
    17821 cacgtaatcc aatcgtcttt gccttccatc catcagctca agaatcatca gctcatgcag
    17881 ctcgtatcgt ccgcgatgca gctatcgcag ctggtgctcc tgaaaactgt gtacagtgga
    17941 tcactgaacc atctatggaa gcaactagtg cccttatgaa ccacgaaggt attgcaacaa
    18001 tccttgcaac aggtggtaat gccatggtta aagccgcata ctcatgtggt aaaccagctc
    18061 ttggggtagg tgccggaaac gttccagctt atgttgaaaa atcagcaaac attcgtcaag
    18121 cagcacacga tatcgtcatg tctaaatcat ttgataacgg tatggtctgt gcatctgaac
    18181 aagcagttat cattgataaa gaaatttacg atgaatttgt agcagagttc aaatcttacc
    18241 acacttactt tgtaaacaaa aaagaaaaag ctcttcttga agagttctgc ttcggcgtca
    18301 aagcaaacag caaaaactgt gctggtgcaa aattgaacgc tgacatcgtt ggtaaaccag
    18361 caacttggat tgcagaacaa gcaggattta cagttccaga aggaacaaac attcttgctg
    18421 cagaatgtaa agaagttggc gaaaatgagc cattgactcg tgaaaaattg tcaccagtta
    18481 ttgcagtttt gaaatctgaa agccgtgaag atggtattac taaggctcgt caaatggttg
    18541 aatttaacgg tcttggacac tcagcagcta tccacacagc tgacgaagaa ttgactaaag
    18601 aatttggtaa agctgttaaa gctattcgtg ttatctgtaa ctcaccttct acttttggtg
    18661 gtatcgggga cgtttacaat gccttcttgc catcattgac acttggatgt ggttcttacg
    18721 gacgcaactc agttggggat aacgttagtg ccattaacct cttgaatatc aaaaaagtcg
    18781 gaagacggag aaataacatg caatggatga aacttccttc aaaaacatac tttgaacgtg
    18841 attcaattca ataccttcaa aaatgtcgtg acgttgaacg tgtcatgatc gttactgacc
    18901 atgccatggt agagcttggt ttccttgatc gtatcatcga acaactggac cttcgtcgca
    18961 ataaggttgt ttaccaaatc tttgcggatg tagaaccgga tccagatatc acaactgtaa
    19021 accgtggtac tgagattatg cgtgccttca aaccagatac catcatcgca ctcggtggtg
    19081 ggtctccaat ggatgctgcc aaagtaatgt ggctcttcta cgagcaacca gaagtggact
    19141 tccgtgacct tgtccaaaaa ttcatggata tccgtaaacg tgccttcaag ttcccattgc
    19201 ttggtaagaa gactaaattc atcgcgattc caactacatc tggtacagga tctgaagtaa
    19261 caccatttgc cgttatctct gataaagcaa acaaccgtaa atacccaatc gctgactact
    19321 cattgacacc aactgtggca atcgtagatc ctgctttggt attgacagtt ccaggatttg
    19381 ttgctgctga tactggtatg gacgtattga ctcacgcgac agaagcatac gtatcacaaa
    19441 tggctagtga ctacactgat ggtttagcac ttcaagccat taaattggtc tttgaaaatc
    19501 tcgaaagctc agttaagaat gcagacttcc actcacgtga gaaaatgcat aacgcttcaa
    19561 caatcgctgg tatggccttt gccaatgcct tcctaggtat ttctcactca atggcccata
    19621 agattggtgc gcaattccac acaatccacg gtcgtacaaa tgctatcttg cttccatacg
    19681 ttatccgtta caacggtaca cgtccagcta agacagcaac atggcctaag tacaactact
    19741 accgtgcaga tgaaaaatac caagatatcg cacgcatgct tggacttcca gcttctactc
    19801 cagaagaagg ggttgaatct tacgcaaaag ctgtctacga actcggtgaa cgtattggga
    19861 tccaaatgaa ttttagagac caaggaattg acgaaaaaga atggaaagaa cattctcgtg
    19921 aattagcctt cctggcttat gaagaccaat gttcaccagc taacccacgt cttccaatgg
    19981 tagaccatat gcaagaaatc atcgaagatg catactatgg ctacaaagaa agaccaggac
    20041 gccgtaaata attgtttatc agtctagaag caagacaaaa actcaatttg agggaaagat
    20101 ccagtaattt ttctatgata aaaggcatcc tatcaaggtt tttgaacacc tgataggatg
    20161 cctttttatg atattgaggc ctttttgccc tttttgaaaa actagaatag aaacaaaata
    20221 tataatagat tgaaactgga atagtacact tctgcttcta aaacattgtt agaattcgat
    20281 ttgactgtcc tgatcgattt gtcctattcc tatttcattt tactatataa aaaatatagt
    20341 atagtagact gaatctaaaa tagtacgaaa caattgctaa aacatttata gaaattaatt
    20401 ttactttcct gatagagttg ttcacatctt atttcaattc actatagttt aatttaagag
    20461 tagtatttac taaggcccaa ttaaaatcaa agagcaaact agaaaacgag tgccattcag
    20521 ctcaaaacac tgatttgaga ttgcagataa gactagcccc tcattaacag gtttacgata
    20581 aaacgatgac aaggtgtgtt gctttttgat ttctaaagag tataatgata gatctctata
    20641 aaataagtgc gaaggaaatg agcttttata gtcctttcgt tttaaaatac tatctcagat
    20701 gttcttatat cgacaagaag tttttgagtc attccctcat catacatatt aaataaatag
    20761 tggctcattc aattttttac tagaataata agctagtata gtaaactgaa ataagatata
    20821 aacaaataaa ttggagctta acatctattt ccagcaattt tttagaaact gcagtggact
    20881 attctaaatt caacacatta taaaaactag agtaaaagaa aaggattgga tcttgtgtaa
    20941 tgcaggatct aatcctttca atcattttgt ccaacttttg gaggttccta caatgtagcc
    21001 gtcattaata aagacagatg ggaacgacag tgttcctatt tattttgata gagatcgatg
    21061 aattctttag atagcaactg aataatctct gttgaagcca tttggtcttc tgcatgcata
    21121 aatagcaagg agaatcctat tttttctcca gtagcttctt tttgtatgag attagagtga
    21181 atcttgtgcg cttctactaa ggagtcttcc gcttcttcaa ctttaatttt cgcttctttt
    21241 aaatttcctg ccttagctag ttggatggct tcaataaagg atgatttggc tgctccacta
    21301 ttggcaatga gctgaaaaca gatatattcc atttcttctg tcatcttatt tctcctatcc
    21361 atgcaagtgc ttgttccaga acttttgctc cattcatcat tccgtaatcc cgcatatcaa
    21421 tggtatctac agggatattt cctgcaattt ctttcacagc aagtaactca taacgaattt
    21481 gtggcccaat tagaatgaca tctgcttcat ggatattctt tttcgcttct gtcattgatt
    21541 ttgcttggat agaaatttca atcccacgtt cagtcgcact ttgttgcatt tttttaacaa
    21601 gcatacttgt cgacattccc gcattacata ctaataaaat ttgtttcata atcttaacct
    21661 tccatttctt gctcaacaac tttgtcatta actttgataa atggaatgta tagaagaact
    21721 ccaagtgcaa agatgatgaa ttgaactaga actgctctca cgtcccctgc tgttgctaac
    21781 catgcattta agaatactgg tgtagtccaa ggaacttgta taaatgcagg actcatgaat
    21841 cctgtaactg ttgctaagta gctgattaaa ataccaagga ctggaactgt gataaatgga
    21901 atagctaatg aaatgttata aacgattggg taaccgaata atactggttc attgatattg
    21961 aagataccag gtccaaaaga taatttagcc acgtttttag aaacagcatt gcgactcact
    22021 aagaatgttg ctattaataa acataatgta gatccactac cacccattaa agcgaatgtt
    22081 tgtatttgtg ataagttgat gatgtgtgga atggcttgtc cattatttgc tgcagtgatg
    22141 ttttcagtaa tgttaattaa tagtaatggt tctaggatgg cactgtaaat aactgcttgg
    22201 tgaataccaa atagccataa catatttcct aaagagtaaa taataatgac cccgattaag
    22261 cttgtaccaa tatgacgaat tggttcttga ataaagattg taatgattga gattaagttc
    22321 attccagtta tattgaataa taatgctgaa acaatcccaa ataaggagat gacagtcatg
    22381 actggaagta atacgctaaa tgatctacta acagctggtg gaatattttc accaaggttc
    22441 atttgtaaag ctttaacgtt tgataattca atgaataatt ctgttgcaat aatcgctacg
    22501 ataaccccgg cgaacattgc gcctgtacct gtgttgttga atgaaagaac acctgaaatg
    22561 tttacagcat cttttgctcc gtcaggaact acagaaactg tatttggcat catcacaatt
    22621 aaagaaacta atgatagcat tgatgctgct gacgggtttt cgaaatctct gtttttagct
    22681 aagaaataac caaccattac agcaataatc atacctgaaa tacttaaagt accgtttgca
    22741 attgttattc cccaatattg gaattttgtt aatgtatccc cttggaaaat ccacttaaat
    22801 accgtgttgt tcaaaagaac gattaaacct gccaaaatat ataatggcat tactgttacg
    22861 aatgcatctc ttagggtttt taaatgaatt tggttcccta gtttaccagc aaaggtggca
    22921 aattgatcta taaattttga gtttttcatc tgaatatctc ctctctttac tcctcaattt
    22981 ctacttcaaa accgttattg tcacttactt tgcgatacca tcttcctgag ctcttgatgg
    23041 ttctcttttg cgtttctaaa tcaacggaga taaatccgta acgattctta tatgcattat
    23101 tccaagacca gcaatcaaat gcggtccaag cgtggtatcc aaaacagaga cttccctctt
    23161 caatggcttt atgtagccat cttaaatgtt cttcataaaa ttcaatacga tacacgtcat
    23221 cgataactcc attttcatcg ataaaccgtg cttcgttttc aacacccatt ccgttctcac
    23281 tgataaacca tgggatatta ccatattctt ccttcacaat catagcaata tcataaatgg
    23341 ctttcggaaa aatttcccaa ccacgatatg gattcatgcg acgctccggc cattcatact
    23401 ctttgaagta ttggtctggc atccagggcg tctgatattc ctcaggattt gcttgtgctt
    23461 gaacacgttt tggatggtag tagtttactc caagaaaatc aaccgtattt gatttcatca
    23521 gttgaagctc tttttcggta tgactccata acacgccatc tctctctagc tgttttacca
    23581 atctttctgg gaaagttcct ttaacagctg gattcaagaa gactttgtta aagaagtctt
    23641 ctgtaaatcg acttgcttct aagtcttctg gagaattact tcttggataa gcaggtgtca
    23701 agtttaaaat aatcccaatc tttccatcaa gtcctaatga gcgatatagt tgaatcactt
    23761 ttgcactagc aaggtttaga ttatagatga cttgtacggc ctcttttccc tttcctttta
    23821 gatttggata atggaaagca tataagtatc ctgcttctgg aatgaccatt ggctcattga
    23881 aagttgtcca gtaatgaacc ttatctccaa agcatgtgaa agcagtcttg gcaaacttca
    23941 cgaataactc cactacatgt ttgctttccc aaccaccgta tttttgaaga agttccactg
    24001 gtaaatcaaa atgatgtaaa ttcatcacaa gatccatctg gttcttttta gcttcttcaa
    24061 tgatggcatt gtagaaagca ataccttttg gatcaggctc acctgtctct aaattcttga
    24121 tgagtcgact ccattggatg gaagtgcgga aagaattaac tccaatttcc ttcatcaagt
    24181 ggaaatcttc ggtgtaagta tgaaaaaagt tactggctac aagaggtccg acattatcga
    24241 aaaaatcttc tggatgcgtt ttgaaccagt agtccatcac attttcatgt acttttccat
    24301 attgaccttc tgtctgaggt ccgctagaag cagctcccca ccaaaacaga ttaggaaata
    24361 ctaacttttt tttcatgctc aacctccttt ctattatgct atacataaag tatagcataa
    24421 ttttaaaatt tgtctagaca tttttaaaaa ttgttgatac atatattgtg tttgcctcat
    24481 ttcttgaact ttgttatact actattagaa tattatagag agaaccagat taaatgagta
    24541 caaaatattt atttatttac aatgagattc gtgaaaagat tctctgtaat aaatatacca
    24601 tgaacgaaca attgcctgat gaaatgacat tagctaaaca gtttgcctgt agtcgaatga
    24661 cgatcaaaaa agctttagac ttgttagttt ctgagggctt aatttttaga aaacgtgggc
    24721 agggaacctt tgttctctct cgtggcagct caaaaagaaa attaatcgtt ccagaaagag
    24781 atatccgggg actgacaaaa atatctgaag atgctcattc tacaattgac tcgaggatta
    24841 ttcacttcaa attagaattt gcaaatgaat ttttagcaga aaaactacag gtcgctttgc
    24901 agagtccagt ttataatatt taccgcctgc gtattattga cggtaaacct tatgttctgg
    24961 aacaaactta tatgagtacc gatgttattc caggtattac tgaagatatt ttacaaaaat
    25021 cgatttacaa ttacattgaa ggaaagttag gattgcatat tgccagtgct acaaaaatct
    25081 tgcgagcttc ttctagttca gaaaatgagc aacattactt gcagctcctt ccaacagaac
    25141 cggtatttga agtagaacaa gtggcttatt tggataacgg aactccgttt gagtactcga
    25201 ttagtcgtca tcgctatgat ttatttgaat ttaattcttt tgcattacga cattcctcct
    25261 aggagaaaat gtgaaaatga agccaatctt ttacaggctc tagtttaaga aaaatttaaa
    25321 acagggcaag aaggtcccat ctatgcttaa atggtttctc ttttctaaat aagatggctt
    25381 taaaagagtg atcgttttat ccatcatgtt gaaaaatatc ttcgtatagc ttatagagta
    25441 ggtactgaaa ttgttcacct gatctacttc ttatagttat ttagttttaa atagtgtttc
    25501 aaacattctt acactgacga gaagtttttg agtcttttct tgtaacacat atagtatact
    25561 gaggttagaa tagtagactg tgacttctaa caaattgcta gaaatgaatt tcaatctccc
    25621 aatttatttg cttatatatt attttaatat attaaataaa ttctggatca taatcattta
    25681 aaaaaatttt atttttttat ttttcattac gaataatata gatgaagggg aaagagtatg
    25741 aaaacagaac tgtttctttt gctattagtt caaaaggaga aaaaatgaaa gtagaaaata
    25801 tttcgtatag ggtggatcat cgtatattgt ttgataatat ttcttttgat acttcgagtt
    25861 cagacgtgac attaattact ggtaaaaatg gtacaggaaa gtcaacttta ctatagtgga
    25921 ttgaaactag aatagtacac atctacttct aaaatattgt tagaaatcga tttgactatc
    25981 ctgatctatt tgtcctgttc ttatttcatt tcactatatc tcaaattgag tatgacgaag
    26041 tgcgctccca tgtcctggga acgcactttc ttcatatttt tcatattctt gaatccatcg
    26101 ataaagacta ttgggatgaa tttttaaagt tgaactaatc atttttacag gatgaggttt
    26161 acagcagaga gtttgaaggc tttatcaaag gtttttcttg gcataatgac ttttcctcgt
    26221 ttccacttaa ttttgtgtct actttattat accaagtcca cccttaagtt agataataaa
    26281 tctaacttaa ggaagctaga aggatgagaa tccaggtggt caagagtccc aaacttaagc
    26341 tgattgggac acccagaata atttgctttt tgaaggcaag gccacgttcc tctatattgg
    26401 gaagtgagag ttgaatgaga gaaccagctg atgaaaaggg tgagatatta gtagatagag
    26461 cgccaataac ggtggctgtt gtgagtaagt gaatatcaat ctggggattt tgagcactga
    26521 tgatagcaat gatgggaaag agggctggag ctacaacgga tagggtggaa ctaaagagtg
    26581 acatcacccc ggctatcaca caaaagaaca gaggtaacca gaaatgagga atggatgttg
    26641 tcatgaggtg ccctatcagt gtgactaaac ctgacttgac cgctagagac attagtaagc
    26701 tcatgccgca gagcatgata attgtagccc agggaacttt agccaaaatg gcttcttgct
    26761 tccctaattt gagccttaag gcgaggcaga ccatgagtat tgagacaaag ccaatatcaa
    26821 atgtttttcg ataagtagct atccaggcga tgtttgggaa aatgagatgc aacaagggaa
    26881 aaagccaaac caaaaccatg ctgctgatca tgagcaaggt ggtttgtctt tgaaccttgc
    26941 tgaggagtgg tggttggtca atagtcaagg atgagtttgt tcttccctta ctatagtgac
    27001 tgtaacagga taataaaagc aagacaatga gtgggtagat aatgctgacg ataaagatat
    27061 gattgccaag tgaaaaagct tgctcttccc atcccatttg cttaaacagg ccttgaaaga
    27121 caatgcctga gctactggtt atcaaattag cccctcctga agctccccaa ttgacggctt
    27181 gagctccaat caaagggtgt ttgtccgctt tttgacagag agtaatcgct agaggacagc
    27241 aaacggccat agtagtgaaa aatccagcac ctaaagcaga caaaagggtt gccatcaggt
    27301 ataaaatcat gtagagggcg ttagggtagg tgcgtgtgcg gtagagaatg tgttgagcca
    27361 aaacatcaag agtaccgtta gttattgcaa agttataaaa gagagagacg ctaaaaatgg
    27421 taaaaaagag tgaggttggc caaaaatgaa gaagttcttt ggggcttaat cccatgagag
    27481 tggttgcgat gaggtaagaa aaagcaatag ccagcaggcc aatattgatt ttggtgcggt
    27541 aaccaattcc aatggctaga gcaatggcgc taatcattat taaatgaatc attgaattgt
    27601 cctttcagtt agaatatgga aataggttgg caattttggc gctcaaaaga ccacctgttt
    27661 cctattggta cttgactatt atacacaaaa aaaatacaat tgtcttgaca attgtattga
    27721 cacttgttag aattaaaaat gaggtattca ggcttgtgat ttcctatgga agttaatagt
    27781 gattgcctct aatgcttaca agtgatatta aaaatagagg acctagtgat gtcaatcatt
    27841 tcaactgatt taaccccttt tcaaatagat gatacattga aagcagcctt gcgagaagat
    27901 gttcattccg aagattacag taccaatgcc atttttgatc atcatggcca agccaaggtg
    27961 tcgctttttg ccaaggaagc tggtgtttta gcggggctaa ccgtttttca aagggttttt
    28021 accctatttg atgccgaggt gaccttccag aatcctcatc aatttaagga tggggatcgt
    28081 ttgactagtg gcgatttggt tttagaaatc ataggctcgg tgagaagtct cttaacatgt
    28141 gaacgcgttg ccttgaattt tttacaacat ttatcaggga ttgcttcgat gacagctgct
    28201 tatgtagaag ccttaggcga tgattgcatt aaggtatttg atactcgaaa aactactcct
    28261 aatttacgtc tttttgagaa atatgcagtg agagttggcg gtggctataa tcatcgcttt
    28321 aatttatcag atgctatcct gctaaaagac aatcacattg cggcagtagg tagtgttcaa
    28381 aaggcaattg ctcaagcgcg tgcctatgcc ccttttgtga aaatggtcga ggtggaagtg
    28441 gaaagccttg ctgctgccga agaagctgcg gcggcgggtg ctgatattat catgttggat
    28501 aatatgtcat tggaacagat tgaacaggcc attaccctaa ttgcaggacg ttctcggatt
    28561 gaatgttctg gaaatattga tatgaccact attagccgtt ttcgtggttt agcgattgat
    28621 tacgtctcca gtggtagttt aacccatagt gctaagagtc ttgatttttc catgaagggg
    28681 ttaacctacc ttgatgtcta agttgtaaaa taaactaact ttttaaagga tgtctttcct
    28741 ctagaacgag ttttatgtca gatagtttaa acgcctctt
//
LOCUS       DAVAZT010000026        28647 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVAZT010000026 DAVAZT010000000
VERSION     DAVAZT010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28647
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.026"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(512..2239)
                     /gene="ezrA"
                     /locus_tag="VQT45_001070"
     CDS             complement(512..2239)
                     /gene="ezrA"
                     /locus_tag="VQT45_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HET2359404.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2321..4267)
                     /gene="gyrB"
                     /locus_tag="VQT45_001071"
     CDS             complement(2321..4267)
                     /gene="gyrB"
                     /locus_tag="VQT45_001071"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HET2359405.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFIPDPKIFTETTTFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4282..4845)
                     /locus_tag="VQT45_001072"
     CDS             complement(4282..4845)
                     /locus_tag="VQT45_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET2359406.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4930..5484)
                     /locus_tag="VQT45_001073"
     CDS             complement(4930..5484)
                     /locus_tag="VQT45_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HET2359407.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5495..6718)
                     /locus_tag="VQT45_001074"
     CDS             complement(5495..6718)
                     /locus_tag="VQT45_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET2359408.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVSLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6755..9205)
                     /locus_tag="VQT45_001075"
     CDS             complement(6755..9205)
                     /locus_tag="VQT45_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HET2359409.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIHISSTKSGRTLLSSL
                     LPESCQAMGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIIGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9404..10333)
                     /locus_tag="VQT45_001076"
     CDS             complement(9404..10333)
                     /locus_tag="VQT45_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET2359410.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            10473..10760
                     /locus_tag="VQT45_001077"
     CDS             10473..10760
                     /locus_tag="VQT45_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HET2359411.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10794..12128)
                     /gene="ciaH"
                     /locus_tag="VQT45_001078"
     CDS             complement(10794..12128)
                     /gene="ciaH"
                     /locus_tag="VQT45_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HET2359412.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12118..12792)
                     /gene="ciaR"
                     /locus_tag="VQT45_001079"
     CDS             complement(12118..12792)
                     /gene="ciaR"
                     /locus_tag="VQT45_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HET2359413.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12901..15447)
                     /locus_tag="VQT45_001080"
     CDS             complement(12901..15447)
                     /locus_tag="VQT45_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HET2359414.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHIAYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15571..16011)
                     /locus_tag="VQT45_001081"
     CDS             complement(15571..16011)
                     /locus_tag="VQT45_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HET2359415.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(15986..16855)
                     /locus_tag="VQT45_001082"
     CDS             complement(15986..16855)
                     /locus_tag="VQT45_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HET2359416.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFTELTNTEANCLVGTKEFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDLESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16897..17625)
                     /locus_tag="VQT45_001083"
     CDS             complement(16897..17625)
                     /locus_tag="VQT45_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2359417.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(17633..18112)
                     /locus_tag="VQT45_001084"
     CDS             complement(17633..18112)
                     /locus_tag="VQT45_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2359418.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELTNFMVDHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVK"
     gene            complement(18123..18821)
                     /locus_tag="VQT45_001085"
     CDS             complement(18123..18821)
                     /locus_tag="VQT45_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HET2359419.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18814..19080)
                     /locus_tag="VQT45_001086"
     CDS             complement(18814..19080)
                     /locus_tag="VQT45_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HET2359420.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(19146..20072)
                     /locus_tag="VQT45_001087"
     CDS             complement(19146..20072)
                     /locus_tag="VQT45_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HET2359421.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFNLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(20147..20962)
                     /locus_tag="VQT45_001088"
     CDS             complement(20147..20962)
                     /locus_tag="VQT45_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359422.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(20966..21286)
                     /locus_tag="VQT45_001089"
     CDS             complement(20966..21286)
                     /locus_tag="VQT45_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET2359423.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLTKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(21583..21663)
                     /locus_tag="VQT45_001090"
                     /pseudo
     CDS             complement(21583..21663)
                     /locus_tag="VQT45_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(21707..23704)
                     /gene="metG"
                     /locus_tag="VQT45_001091"
     CDS             complement(21707..23704)
                     /gene="metG"
                     /locus_tag="VQT45_001091"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HET2359424.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEYDGKLTLLTVDPAVPNGSVIG"
     gene            complement(23828..25087)
                     /locus_tag="VQT45_001092"
     CDS             complement(23828..25087)
                     /locus_tag="VQT45_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2359425.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKKSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(25089..25790)
                     /locus_tag="VQT45_001093"
     CDS             complement(25089..25790)
                     /locus_tag="VQT45_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2359426.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(25774..26973)
                     /locus_tag="VQT45_001094"
     CDS             complement(25774..26973)
                     /locus_tag="VQT45_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HET2359427.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTAVKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILIPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            27259..28605
                     /gene="gor"
                     /locus_tag="VQT45_001095"
     CDS             27259..28605
                     /gene="gor"
                     /locus_tag="VQT45_001095"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HET2359428.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
BASE COUNT         8572 a         6299 c         5114 g         8662 t
ORIGIN      
        1 ttttagtcta gtataaatag cgagaaatat ctatcctatc ttctagaatg tcttccaaac
       61 gagaaaactc tcgtaaacaa agaggtttta gaggcctatt taccgtggac taaagttgta
      121 caagaaaagt gcaaataaga aatctccaga ttaggaacta tccgtgagtt ctctagtctg
      181 gagatttttc aatagacttc gttattggac ggttaccaag ttacttcaaa gtacagattt
      241 gaagctgcag ataagactga cgaaatcact ttaatactaa atgaaaatca aaaagcaaac
      301 taagaagcta gcctcaggct gtacttgagt acggtaaggc gacgctgacg tgatttgaag
      361 agattttcga agagtataaa acactgtttt gaagtggtgg ataaatcggc tgggtaaaaa
      421 ctcaatctca ggagaaaatg aagtaaatct ccccacaact atagaaaaag atttgattct
      481 gctcctcaca caataaaatc tttttctttt attaaaaacg aatcgtttca cgtgttttct
      541 catatgaggt aacaaagcga ttggttacac caggctctgc cacttccaat gcttgagaaa
      601 tcttgtcaaa tgaagcgtga taatcaaatt ctttttcaaa aatatctaaa gcttcgttaa
      661 atgcttcttg aatgcgttca tcaaatgagc gatagcggtt agaatattgc aagagttgct
      721 ctgtcaaagt tgcatattgt acaatattat aagtttccgt ttctaaagct tccatatcat
      781 tcgttgcaat ttcaagaact cgggtaacag attcaatgtt aatcattttt tgttctaact
      841 caaccattaa atcctcggta ttattgcttg ccgtaaagaa taacttcaag aaagtttgtg
      901 gaatacctgg cagattgcgt ttttccatgt atcgcttgat agtatggaga cgattgacat
      961 aaacattggc cttttgacgt gcattaatat catctttctc aatttgtgtc aggcgctcac
     1021 taactgaaat ttgctcatct tcaatatctt ttagttgagt ttgtaaatcc tcaagatttt
     1081 cttcaagaac tgaataagct tgggttggtt cttcttgatt tgaagttacc tcaacaatag
     1141 ctgcctcaaa actctctaat tctgtctgaa tacgacgaac atggcttgca gctgtctcag
     1201 gaagtaaata ggtcttgttc aaacgtgcaa tatcttctcc caataaagta ttattctctt
     1261 tcatatgttg aaggtaagtt ggaagagttg caagtagatt ttccactact ttctgagcag
     1321 caatttctcg agtaaaaata tcatacaagg cattgatttc ctcttgtgcc tgtccattct
     1381 catattcggc attatccaat tccaactgac gaatattctc ttggtttttc ttgaatgctt
     1441 cataaagcaa gtggaaacgc gcttcaatat ccgtttcaac aaaatgataa ttagcatcaa
     1501 ttagtttacg ataaccggct tccaaatcct gtaattgatc tggcaattct gtagaaagcg
     1561 tcgtaaccaa ggctggaaca cgatccacaa tatgacttaa ggccaaaatg tgattttctg
     1621 tattatccaa aatcactgcg gcttccacag ggtcacccga tgaattcaag gttacaaatt
     1681 gtgaaaattc agattggata ttttctaatt gtttttcaat ttcatccaag gcttgaccat
     1741 actgttctga attttcagca actctatgct gaagttcctc aaataaatcc aaagcatgaa
     1801 gaacacgacc actattttta gattcttgct tctctaagtc tgccaaagca ttgcgaattg
     1861 ccgcaatatc ttcttcaatc aaagtaattt gactctcaat ttggtcaatt tgatgactgg
     1921 ccttgagaaa acgaaatgaa tggttataac cttctgcttc aaagagatta ttttcaatat
     1981 cggcaaaaga gttgagagat aaatcgaccc atttttgatt ccattcacgg aaagccactt
     2041 gactttgtcc aatcaagtgc atatttttta cagcttctac ttcatcattt actggaagat
     2101 tgtatagttc ttcttttctt tcttctagcg cctctaatct cccctcgttt cgcttacgta
     2161 gaaagattgc cactacataa gccagaacta aaatgactgc aattgcaacc attaaataaa
     2221 ttagttgtcc attagacata tcaaactcct tttttacttg aaacaatcgt aacgattata
     2281 tcatattttt tagaccaagg gaactacttc tccctatttt ttagacatca agtgtactat
     2341 agacagcatt ttcttcgata aactcacgac gaggctctac tcgatccccc atcaacatat
     2401 caaagatttt atctgcttct gcagcatcat ctacagaaac tctagccatc aagcgatgtt
     2461 cgggatccat ggttgtttcc cacagctgat gatcgtccat ttcacctagc cccttataac
     2521 gctgaatagt cggtttggta cgaccttcac tataacgggc taaagcttct tggagtttga
     2581 tttcttgatc tgcacccggc tggatatatt ctttaatctc gcttccaacc ttgacaccat
     2641 agattggtgg ttgggcaata taaacataac cagcttctag gattggtttc atataacgat
     2701 aaatcaaggt taaaagaagg gtacgaatat gggctccatc gacatcggca tcggtcatca
     2761 aaacgagttt ttggtaacgg gctttcgaaa catcaaattc tgcgccaaat cctgttccca
     2821 tggctgtgaa aagactacga atttcttcgt tagctagaat cttatccata cttgcttttt
     2881 caacgttcaa aatcttaccg cgaattggaa ggatagcctg aaactcacgg ttacgaccag
     2941 atttggctga tccaccagct gagtctcctt cgacgatgaa gagttctgtt tcagcagggt
     3001 tattagaaga acagtctgct agtttccctg gaaggttgga aatttccaaa ccagattttt
     3061 tacgtgtgac ttcacgcgca cgcttggcag ccacacgagc cttggcagct aaaatccctt
     3121 tttccacgat acgtttggca atctgtggat tttccatgag gaaatcggag aaggcttcac
     3181 tgaagaggcg attggtaatc ttgaccactt cgctatttcc caatttggtc ttggtttgtc
     3241 cttcaaactg tggatttggg tgtttaactg agataactgc agttaatcct tcgcgaacat
     3301 cttcccctgt taaattatct tcattgtctt tcagtaactt attcttacga gcataatcat
     3361 tgataacacg agtcagtgcc gtacggaaac cttgttcatg cgttccacct tcatgggtat
     3421 gaatattatt ggcgaaactc atgacatttt catggtaacc tgttgtgtac tgcatggcta
     3481 cctcaactgt gatatcatcc atctcaccgt ctgtatagat tggtgtatca aagattacat
     3541 ccttgttctc gttgatatat tcaacgtaac tagcaatccc accttcataa tgataatgct
     3601 tggtttgttc caaaccttgg cgcttatcag tgatagaaat ttgaagaccg cgatttagaa
     3661 aggccaactc ttgaatccgt ttatttaatt tatcaaaatc aaaggttgtt gtttcagtaa
     3721 agatttttgg gtccggtatg aagtgaaccg ttgttccagt tctatctgta tccccaacca
     3781 cctcaaggtc tgcaacaaca tgaccacgac ggtattcttg gtaatgaatc ttaccgtttt
     3841 tatggacatg aacgtctaat tgagtggaaa gggcattaac tactgacgac cccaccccgt
     3901 gaagaccacc tgaaaccttg tatccaccac cgccgaactt tcctccagca tgaaggactg
     3961 taaagacggt ctcaacagca ggacggcctg ttttttcctg aatatcgact gggataccac
     4021 gcccatcatc cacaacagta atcgaatcat ctggctcaat aaaaacttga atatggctgg
     4081 caaatcctgc caaggcctcg tcaattgagt tatcaacaat ttcccagact agatggtgaa
     4141 gaccttcttt tgaggttgat ccaatgtaca tccctggacg catacgaaca gcctctaagc
     4201 cctctaaaac ttgaatttga ctggcatcat aatcctgtgc ctgcagattt ttgatttctt
     4261 ctgtcatctt attccttttt cttatatgtc taatacttgt cttaaattca cgatactggt
     4321 aaacaagtgg gtatcaagtc ctgcagcttg acctgcttcg atatcaatcg gccgatcacc
     4381 aatgacaaga ccagagctaa tctgatactt ttctcttaaa taaagcatgg attcgggatt
     4441 tggctttctc ttaaagcctg agctagaagt caccacttct gtaaaataag ctgctataga
     4501 ggttttttct aaaatttcca aaacctgatc atttcgatga gagaccaaaa aatgacggcc
     4561 accttgattt aaaatgtctt ccaataggtc agaaactcct tcaaataaaa tcgggtgttc
     4621 aagctctctg gcttcatttt ccttgtactt ttctaaaaaa ttctctaaat tgggagcgaa
     4681 tgtctcaatc gcaaaaggag tagaaacctt taaagcttga tagacactgt catggtcttg
     4741 tgtgatacca tacagtgcca atgtttcaac aaatgcagct gttgaagttt cataattatc
     4801 cagtaaagtt ccacctaaat cccagatgta atcgtgatat ttcataccct tcattatagc
     4861 atttttttat gaaaaaagcg atgatttccc tgagttttcc acataaaaaa cgagagaata
     4921 actcccgttt tactgatttt taccaaagac atctcgatag agcattcctg ttcgtaaact
     4981 ctctgcgtcc cctcctagtt gctccaccaa ctcgtaggca aaggcaaggg ctgttgaagg
     5041 accccgactg gttgtcaact gaccatctac cactactgtt tccttgacgt agtgaccatc
     5101 aaggatttgc tcttgaacgc cgtcataaca agtgtatcgc ttatttttca atatctctgc
     5161 ttgattgagg gcaattggtg ccgcacaaat ggctgctagt ttcttccctt cttgctcgaa
     5221 gctttgcaat tcttgaatca aggtctgatt atcacgtaaa tgtgcagaac caggcatacc
     5281 tccaggaaga acaatcatat catagtctga taaatctcca tcaaagacat gatctgctct
     5341 tacttggatt gcatgcgaac ccgttacttg ctcttcaaaa ccaaccatat cacatgtgat
     5401 attggctcga cgcaagacat ctacaactgt caaggcttca atttcttcaa agccctgagc
     5461 taacataact gctactttta ccatgatttt ctccttattt aatttgtttt aatacaacct
     5521 ttttccgttt gaatgggact tttccgctct tttcttcagc tagattagtc tggtaactca
     5581 tcgataaaag caaaccaaca ccaatcagat tactgataat agctgatccc ccttgcgaaa
     5641 tgaaaggcaa gggaatcccc gtcaaaggaa gtagtccagt cacagcaccg atattctcaa
     5701 agatgtggaa gagcaacatc ataatcaaac ctgtggaaat ataagtgtag aactggttat
     5761 ttgatttaag agtaatcttc aacatacggt aaatcaacat gagatagagg gcaataacca
     5821 ggacagagcc aataaagcca aaatcttctg caataaccgt aaaaatcata tctgactctc
     5881 gaactgggat aagcagattc gaagcattaa atccctgacc aaataagcca ccactcccaa
     5941 tggcaatctg cccttgagcc tgctggtaag tcgttgtttg ggcaaactca aagggattga
     6001 gccaagccaa aatccgattg atttggtagg tcggcattcc aatctggtga agaaaagctc
     6061 gtccgtcctt gctaataaag atagctaaga aaccagcaac tcctgttaca gcagtcacaa
     6121 atactgggat aataattttc caagaaaccc ctgataataa aacgattcct gagaaaatgg
     6181 ctacaaaaac caaagccgtc cccaagtcac tttgaagtgc taaaagaact aggactggaa
     6241 tggtaaagag aatcatccag aaaattaaca aaaagtccag cgaaaccgtg cgtctccatt
     6301 ccttatgttt ctttgtaaat tggacaatga cacgagccaa catgaggata taggatatct
     6361 tcataaattc tgacggttga aatagggtaa ttccatttat tgatacccag tttttggcac
     6421 ccgttgatgc aactaagctt ggattataaa atacaatcgg caagatcata agtcccaagc
     6481 ctaaaatata tagaaagggg gtcaccttcc aaagaaattc tgtattaaag agcatgacca
     6541 caaaaccaat cacaagcccc aaggcaatcc aggcgacctg ctgccctaaa atgggcagaa
     6601 tattattggg ataatcatga ctaacggcta tatagatagc caccacaccg atgaccagta
     6661 gaaaaaatac tggcaagagc aaactataat cgactctaga gtcgagagaa cgtttcatat
     6721 atactaacct tatactttca tacaatacta tttatcaaag ttcattaaaa aatctatcaa
     6781 tagcctcgtc aacttcggat cgagagatgg ttttaacagt cgcttcttct gctagagatg
     6841 ctactatttg tttgccgtat cgttttccga tgattctcct atccaaaata agagttaagg
     6901 aacgttggta ttcacgtctc atacttcttc ccaaagcctg ttttaaacga ataatggcca
     6961 ttggcaattg ataatcataa aaggcatttt tcccttcttg attcagttct tgattaatct
     7021 ttttcgtcaa gggttcttga ggattttgga aaggaagcct cggtacaact tgaatcacaa
     7081 aaggatggct tgaaaaatca actccctccc agaaacttgc tgcaccaagc aagatttgtt
     7141 gttcaccttt ttcaaagcgt ttctttagct gatgaacatc cccattttta tactgggcca
     7201 agtggctaac tgtaagtaaa tccgatactg ctagaagcat gtctttagcg gtaaagagaa
     7261 ccaaaatcgg ttgctggaaa gcttgaattt ccactagtaa agcagctacc tctctggcat
     7321 agacttctaa ggaggtttct gttaccagag ggaaatcttt gaccataacc acttcttgtt
     7381 cctgttttcc ccgagattca atcttgacaa atttggcttc aggatagcct aaaaggtctg
     7441 ccaaagaaac cctctgacta atctcaagag tagccgatac tcccatggct tggcaactct
     7501 caggaagtaa agaggacaga agagtacggc ctgattttgt agaagaaata tgaattttct
     7561 tttgactcgt ttcagttact tcaagccagt aatcaccttc agctgtaaaa tagcgaacca
     7621 gctcatcaaa gccttctact tctaattctg aaaaatactg atggagattg tccagagaat
     7681 ctaagatatt tttcctagat ttaccagact gaaattgttc tatcaagtag agacactcaa
     7741 agcgaatact ttctagtatc cgttgttgaa ccctgttttc ttctcctact aaagccttat
     7801 caattaaatc gataatagat tgtatatcgt aggtctcttg aagcagattt tctagagcta
     7861 acaaaatctt ttggacttca tcaataatca gtaaacggtc actgacaaat tcaggattat
     7921 cttcaagtct ggtcacgaga taggcatgat tagtcactaa aagcttgcaa gtctctgccc
     7981 tttcttgact acgtttccaa aaatcttccg tcacaaataa gctctgggat gataaattcc
     8041 catcatgacg aaggtctgct agaaaatgtt ggtaacgata gagttgcccg atttcatcca
     8101 aatctcctgt ctctgtctca gtaagccaga ccaagacttg cattttaaag cgtctaaata
     8161 agcgattttc atcattttcc tgcaaggaat gataaaaggc atccaacttc agataatttt
     8221 gtggtccctt taagctatga atatctgtat ggaacacttc cttgaggcgt ttaccttctt
     8281 cttccatgat ttgattttga agaatctttg tcggaacact aagaacaatt tgtcgctctt
     8341 tggattgaga taaagcgggt aagagatagc cataggtttt cccaatccct gtcggcgctt
     8401 gaatcagaga gacaggttca tctttcaata gcaagccaac ctctttagca aaactttctt
     8461 gttcctccct cacttcaagg ttcaacagag aaatattttt agaaaagtct tgagatagtt
     8521 ttcgtggctc cagagaagct gccgttttct taaaatacag accttgaact tggaccaagt
     8581 ctggagaact caggatagat tggttgcgat aagtttcctc aataaccagg taggactcat
     8641 ataggagagc gtcagccatt tccagcaagc gttccaagag acctttagga agctgagtca
     8701 tcttttcccg taaaaaaaga agtaattctg ctgtagcttg ggcatctgaa agggctgtgt
     8761 gtgcgtgttt aagaggaatt cctaattctc gacacaaaat cggcaagcta tatttttcca
     8821 gttcagggaa aaagacctgg gccaattcga ccgtatcaac acgagggttt cttagctcat
     8881 agccttcaaa aaataaattt tccgccaaga gattagcatc aaactgaaca ttatgggcta
     8941 caaaaatccc atcctccacc aagtcaaata tttttctggc aacttgcgaa aaatcaggtg
     9001 cttgcgccag acgttggtct gtcaatcctg tcagttcttt gatatgagca tccaagggtt
     9061 catgtggatt gacatccgtc gtatagtgat cgacgatttc tccgtcctca atcacgacaa
     9121 ttcccacttg gataatttta gccttactac ctgtgctagt tgcctctaaa tccaccacaa
     9181 catagcgatt accaatcgtt ttcattataa aaaattatac caaaaaaagg gccatttggc
     9241 acctgcaaac ataggataat tttcaaactc aagaacacta cttttcttaa aaatcccatc
     9301 gaatagagca ttctagcctg ctgatttttt aaaatagtga agaaatacga aaaattgaga
     9361 gaagaaatgt tttcatcttc cttctctcaa cgaatcatgt attttattta accatgtcag
     9421 gatcgtagtc ataaaatcct gtatcaagga aacggttttt agggtgaagt ttacgaactt
     9481 cttcatccag caagaaggct tggtcatggc taaagttgcc ctcttgaatc aagctacgcg
     9541 cttggataaa gagttttgca atctcaacaa agttctgacc aggagtgtag agcccttcta
     9601 gtttccagcg agtaaagcca tgctccacca attctgttaa tttgatcatc aaatcaaggt
     9661 cattgttggc aaagatatgg gtcccatgat tatcttcaaa aatggaatag tggctctctg
     9721 gatcacttgg ctcagccaag aagaggtcac gtttatgcgt cttttcatca tcgatatgtg
     9781 taaagttata gtagttttgc aagagtggac gtttagaatg atggatgacg ctagcaccgt
     9841 aaaccaaaac ttcagcagga atttccaaaa tctctggcat tttgaaaagt tcagctgatg
     9901 gaatttcacg cgccaaaaca gcctcagatg cgccagcctt ttgtccccag aagttaatct
     9961 gacgactgct agttaccatg gttgaagcat cgtagatggt cttaaatgaa taaccatcgc
    10021 ggttaactac gtaaaagacg cctgcatccc caatcgtaat atagtctgtc ttgatttctt
    10081 ccaagaagtc taagaaaggc ttgatacggt ccatcatatc ttggtgcatg agagcattga
    10141 ccgcaacgag caattcctta ccagcatcat gaaccaactt agcgatttca cgtaattggt
    10201 cataactaaa ggtcgttggc agacgaaggc caaaatcttt ctcaccgaca tagatacggt
    10261 ctacgccagc ttcgagtagt tgttcaactt gttcaatact ttcagcagtt gctgtaatga
    10321 caatcttttc cataagaaaa attataccac atttctccaa aatcatccat gctttgaaaa
    10381 tgaaaaggga ctttattctt tttgtaacct ttctgtaata attctctgcc gaaaaaatga
    10441 taaaataggt atgtactgtt aaggagagaa ttatgcccgt aagaaaatta caatcctatg
    10501 aggtagacta tcaagaagaa ttaaaccagc agcttcctca ttaccaagct tatacacctg
    10561 aagcgcaatc tgatgccaat ctcaaggaaa tcctattttt tattaatatc gctgtttttt
    10621 gtatctgtat tgctatcttt agttttatct ttttagcatt aaaattatca actgctcttg
    10681 cctttgccgc agcaatcgga ttcagcttac ttgttttaaa agttcaacgg tctattatca
    10741 aacgaaaacg tagaagataa atccaaaata tcgccccagt tggagcgata tttttatttt
    10801 ttctttttag atggtgtctg aatggcaatc ttcacttcaa agattgttcc cttgggttta
    10861 ttatctttga cagtaacagt tccttttaga gcatctacaa tttgcttggc tagggataat
    10921 cctaaaccaa aaccaccttt ttgccgagtt ctagccttgt ctactcgata aaaacggtca
    10981 aaaattttct ttttatcttc tgtcgaaata ccgattccat tatcagaaac aagtaaataa
    11041 agattgcgat cggtcgccga gataagaaaa tcaatttcac catcctcctc agtatacttg
    11101 acggcattat cgaaaagaat ggtcatcagt tgtttcagaa gaagctgatc tgtgacaatt
    11161 gttcgatgga tacgattttc aaaacggaag acacgattat tttccgaagc aatcatctcg
    11221 tagtttgtga aagttgtatt aaaaaagcta gttggaactt ctgcaagctc cggcttaatc
    11281 ccatcatctc tccgagctaa gttcagcaag cttgtcgtta aaaaacgcat atttcggact
    11341 tcttccaaac tcgatgcaat gctttcgctc acatccataa tggtagcttc tggcttacga
    11401 aaaagggtct ctaagcgatt ttgcaaaact gcgagtggag ttcgtaactc atgactggca
    11461 ttttccacaa aagactgttg cttctgcata ctctcaagca ggggcctaac actgacccta
    11521 gctagataga gactggcaag taaagacaaa atccagaaac tagccatcac gaccacaatc
    11581 aattgctcat gcttttgact agcctgttcc aactgactgg tattaatcaa gacagcagca
    11641 tacttgatat tggttgaaac cgaactaata ttggtctcca tcaaaatcac acgatagatt
    11701 tcttcctgcc catagctatt aaaaacctga atctggtaga tatgtcctag ttctttcttt
    11761 tctaacttaa tcttatccaa gcccaaaaat cgatttccag aaagaagttg agtaaagtct
    11821 ttatcaaaga gaatgacttc cgtattggaa ctgacattag gttttatttc tactttacta
    11881 gcgtccgccc tagcattttc taaatcttta atctcttctg ttgccctatt tatagccagc
    11941 tgaataactg cttgaggatt ttcactcagt ccatgaagct tatcgtccac cgaagtataa
    12001 agactcgaat gcatgacttg taaaataatc agagtcattg tagaaaaaat cagggtgaag
    12061 acaccgaagt tgcggataaa ataactaaag tcatccgcat accatgtttt tttaagttta
    12121 ctgaacatct tttaaaagat acccaacact acgcaaagtt tgcaaattct ctgcaaaagt
    12181 ggttcccttt aatttcttac ggacttttga aacatagact tcgacaaccg aaatcgttgt
    12241 atcactatca aatccccata gacggtcaaa aatctgcgtc ttaggcaaaa tcacattttg
    12301 attttgaagg aaataaacta gtaaatcgaa ctctttcccc agcaattcga caggagtatc
    12361 ttcaacttta acggtattgg ttgataaatt aaccacgata ttcccataag tcaaggtgtt
    12421 ttcattaaac ttccctgaac gtttgagaag ggcctgaatc cgcattttaa gttcttctag
    12481 gtagaaaggt ttggtcagat aatcatccgc tcccagttca aatccatgtc ccttgtcatc
    12541 caaactttcc ttggcagtca taatcagaac tggtgtcgta attccctttt cacgcaattc
    12601 ttttaagact tggaaaccat ttttttctgg caacatcaaa tccagcaaaa tcaagtcata
    12661 gacaccactc tcagcttcgt agagaccttc ttctccatca aatacctgca taacatccgc
    12721 aaaatcgtct aaaaagtcaa atactgaatt tgacagacct aggtcatcct caaccaataa
    12781 gatttttatc atgagaaact cctccttatt aaaactatta taccaaattt gccttaaaaa
    12841 aaactcaact ctctgcattt tacatgagat agctgagttt tctttttatt ttaggcttat
    12901 ttatgcattt ccgtattgaa gaacaactgc ttcgactgca gctttttcac ggctaatcaa
    12961 gtcaacacgc gctgcaattt ccttgattcc cataccgatg ttacggctaa gagcaaggtc
    13021 agaaagttgc ggctcaaaga actccttgta ttccgccaag cgttgctgag tcttaaatac
    13081 atgagcagga aggataacaa agctatcaaa gctcatatct cctccaaggg ctgccttaat
    13141 ccaagcccag ttttcacgcg cccaagacca agctgttttc tgagttgctt gatgagctag
    13201 gaattggtaa taccaagcag acaagtcctg tggtttgacc acaaatttgt ccttccaaga
    13261 agtaatcaag ttttggatat tatccgcatc tgtactgtat gcaagagctg ctgccaactg
    13321 gcgtttaaag acagcatctg ttgcgtgagt ataagtatca agataaagtg ctaacaagtc
    13381 tttagtctca tgatgtttca tctcattaat cagaacttgt gaacgaatag ctgctgggag
    13441 tcctgcaaga ttctccttgt gtgttgcgaa gatttggcta gcgacttgac tagcttctgc
    13501 atcatttgag cgaatcatca tcgaaacagc cagctgacga accaattcat cctcatctga
    13561 ttctccgtct ttagcttcaa aaccaagacg gtcatagtta tgacgagcca atttagcaac
    13621 cagtcctttg aaggctgttt cagcatccgt tccttcatca ataaagcgct caagggctga
    13681 aatcacttga gaaacagctg aaaccaccag ataagactct tccttagcaa gtttatcaag
    13741 aactggaagc aagtctgcat aagcaatgtg ccctgcctca gccaacaaac gacgttcttg
    13801 aacaatttgc agtttgcttg tgttatcaag tgtctctagc tcagcaagaa cagcttctaa
    13861 caagtctcct tgatagtcgg taatatagtg ggcagtattt tcagtgttga gacgaagagc
    13921 tccttcattt tcagcaagaa gagctgcgta gccagggatt tcgatacttt cagtttcgag
    13981 tgtatcaggc aagcctttcc agttgctatt gaggggcacc acccagagac ggttcttgtc
    14041 ttcgttctca ccgatgaaga attgtttttg tgaaatcttc aagacatcat tttcaacttt
    14101 aacagtaaga actgggtaac caggctgttc caaccaagaa tccatgaagg ctgcgacatc
    14161 acgtcctgac gcttgaccaa gggcatccca aaggtcacta ccaatggtgt tgctgtattg
    14221 gtgtttttca aagtaggcgt gcaaaccttt agcaaaatca gcatctccta gccaacggcg
    14281 aagcatgtgc atgagacggc ttcctttggc atagacgata gcgccgtcaa agagtgtatt
    14341 gatttcatct ggatgtttaa cttcgacgtg gacagactga acgccatcag tagcgtcacg
    14401 ttcaagagca agaggtactc cacctgtttg gaaatcttca aagatattcc agcttggttc
    14461 gatggtatcc acacagacgt attccatcat attagcgaaa ctttcattga gccaaaggtc
    14521 atcccaccat ttcatagtca cgaggttccc aaaccattgg tgagccaatt catgggccac
    14581 aacaagggca acttgttgac ggctagcaaa tgtagagttc tcatcgacaa ccaagtaaac
    14641 ttcacggtag gtcacaagac cccagttttc catagcacca gctgagaagt caggaagggc
    14701 gatgtggaga gattgaggaa ttgggtactt aactccatag taatcttcgt aaaactcgat
    14761 agagcgaaca gcgatatcca gtgagaaatc aagatttgaa agtggatgtg ctttggttga
    14821 gtagacacct accagggtac catttttagt tttagcggtc accccttgca aatcaccagc
    14881 aacaaaggcc aacaagtaag aagacatgcg aggtgttgtc tcaaacttcc agatacctgt
    14941 ttccttacgg ttttcaacat cgatttctgg catgtttgac aaggccaatt caccttctgc
    15001 ttggtcaaag cgaagagaga ggtcaaaagt tgctttggct tcaggctcat ccacacatgg
    15061 gaaagcttcg cgcgcaaaat ggctctcgaa ctgagtagac aagacctcct tcttgactcc
    15121 atcaactgta taataagaag ggtaaatccc tgtcatgttg tctgtaattt taccagaaaa
    15181 ggcaagaacc aattcaactt gaccagcctc agccaattcg atatgaaggg cttcattgtc
    15241 atggtcaact gtaaatggac gagcttgacc tgcaacttct acagaggtga tttccaagtc
    15301 tttttggtgg agggagatgc ggtcactctg tgcttgacca gtgatggtca ctttcccaga
    15361 aaaagtcttg gtctcacgac tcaaatctaa aaataaatca taatgttcag gaacaaattg
    15421 cttaataaaa tgttcaactg cttgcatagt tttctcctat tctaagttta agagctactg
    15481 ctcttcttca aacaaactta ttatatcata ttttgcttga gaaaaaagga ttggacagcg
    15541 atttccaaaa ctttcttcct tctaaatagt ctacagtggg tagaccttgc gaaattcttc
    15601 taaaacaacc ttgctttcag gtgtaaaagt cagccctact tcacccaaac agtctgtgaa
    15661 aaagtcctca tgaacctggc gccaataggc aagtgatttg tctccctcac cttccttaaa
    15721 ggcatgttgc gcagaaactt gattgaagag ttcaacagaa acctttgtaa tttcgacaat
    15781 gcagacagac tgattttgac tatctaaaat gacatcgaag gtccctactt ggggaagtgg
    15841 ttcgtcttct agtacataga ggtcataggc tgatgctgtt gctgtctttt ctcctttaaa
    15901 caccaaatcc gctaaaaggt ctggttcaac tccaaaagcc caagcatcga tttcatctcc
    15961 gatcaaagga ttgatttgct tgtatttatt ccacatttct tgcggtatca tgggtactcc
    16021 tttgtaattt tttactttct tcttttatgt gtttaagatg atctggatgg tcaatctcta
    16081 aatcaaaaat ctctggaata gaactgtagt ggataatgca cttgataccc aactgattca
    16141 ttttttgtat gaaagaagta ttcagatagc ctgctacagc aaaattaatc ttgttctttc
    16201 ttgctttatc ctgcatatct cttagcatat ctaacattat tggactttcc agatcatgcc
    16261 attgactgtt tctcatagtc gcaaaaacaa aggaagtcaa atcattcatt ccaactacaa
    16321 tctttgaaat gcccgtttcc agtatactag ataagtcaaa atacgctgac ggtaattcaa
    16381 tcatcgttcc gactttccca gtaaagccat actgacgcaa tactgtaata gcttgtttta
    16441 attggtcggc atcattgaca aaaggaaaga taacagatag attggggttg gtttgataaa
    16501 cttctgtaac gacatgtgct tcagcctgaa attcatccaa acacgccagt aaacgcctgg
    16561 ttcctctata gccaaacaag ggatgccctt cgtcaaaaaa ctctttagtc cccactaaac
    16621 aattggcttc tgtattcgtt aattcagtaa aacgatacca aacttcttca tctgagtaca
    16681 gggagcagat agtctctaga taatctttta caaattgctg acaacttgct aatatgatgt
    16741 tttgattaag ctctctcaac aaatattccc cacgaatcat gccgacgtgg tgaaatagtt
    16801 gaggataaat tttttcaaga attttttcgc cactaagggc aagttgattt ctcatagcca
    16861 ttcacctcgt cttaaaagat acaatatcat atataattat atcaaaattt cctctagttc
    16921 aaaagcttca taaggttcag ataactcata tcctaaaaat tctgctactt ttttggaagc
    16981 ctcattatga gcatcccaaa gtggaaacat atctctattt aaactctcta gaatcattgc
    17041 agcaccaagc tttttagcaa atccatttcc ttgttcgttt ggtctagttg caacttccac
    17101 ttcaactgct ttacggtaaa ctaaccctga ggaaatccca gcaatcagtt cattattttt
    17161 aagaatcaca aagccaaatc caccttttaa aacaaaatcc tgataggact caaaatcccc
    17221 ctgtaaatcc tgtgaccatt cttccgtaga aaagcagtta taaatatgat tatcaatagg
    17281 cacaatattg taaccttcct ctaaatgagt aactagatta tttaaaaatt caacttgaaa
    17341 atttgcctta tctttaaaag aatagcgagt aaaagaattt agccccactt ttcgatgcag
    17401 aaaatcttgc caattagtat tttctgaaat aataatctta taatctaaac catattttct
    17461 aacaaaatct tcccaaaatc tggaatccaa ctcccctgct aggtatagaa aattcccaac
    17521 atcataaaag cttgttgtcc tatcattgtt tcggtagaca gttccaattt gagatttaag
    17581 accatagaga accatatttt tcttccatgt tttaaatagt tccattatcc ctctacttca
    17641 ccttccaatt catgtaagaa gtcttgtcca gttctggaaa tcctaataat tcagacttaa
    17701 ccttcaagac taatggcgat gcattttctt ctgtaatctc ttgaatatcc atccaaatat
    17761 atccaagtga atcattcgca ccatcagaca cagcttccga agtcgtaact tgaggtgcac
    17821 tctcattcat ttcaacatca tacaaggcca tgacatggtc aaccataaaa tttgttaact
    17881 cttctctgac gaaaacatcg tagattcgag gattagagta gcttctaaca gtaaatcccg
    17941 tctcttccat aacttctcta gtcagcgttt ccgtcagtcc ttcaccaagt tgctgactgc
    18001 ctccaggtag atcataccga tgttgataag ggcctctcgt tttttcaatg cagagtaact
    18061 tcccattttc taagcaaaca gcgtagactc caaagtgttt tttgatttcc atccaactcc
    18121 tcctacttca aagaccagcc accatctatt gtcaagattt gtccttgcat ggcgctcgct
    18181 tttccacttg ctaaaaaaag actaagctct gctatttcct ctggctcaat ccagcgcttg
    18241 attggagttt cactagccac ccagtcagcc aaaccacctg gttcaaaatc cgcagcggtc
    18301 atagctgtct tgactgctcc tggagcgata ccaaagacct gaatcccagc ttcagcatag
    18361 tctagagcca actgcttggt gaagccagcc aaggcatgct tggatgaagt ataggcgtga
    18421 ccacctccac ctgctaggct agaagcaatg gaacacatat tgatgatgat tcccttttta
    18481 ttttccagca tttgtgtcaa ataataccga gtcaactcta ctggaataat gtagttgatt
    18541 tcaaaaatct cttgaatgtc ctgcgccgtt tgttccaaca gtggtttgta atcatccaaa
    18601 actccagcag tattacacaa aacatccacc tgagggcacc agtcaaaaat aggttccaag
    18661 tccaaggtca aatctctctg taaaaagtga aaatcaccct ctaagagtgg cttttcacct
    18721 tggtcaactc cataaacttg atagcccttc tctaaaaaga ggcgagcttg agccaatccg
    18781 atccctgaac tcactcctgt aatgagtaca cgtttagtca tgcacttcta cccaatccgt
    18841 tgccaaaaca tcacaaactg tcgggctcca catggaaaaa ccttctcctt cgccagaaac
    18901 gttgattagg aaataaggtg tcatttcaag tgcaagccca ttttgctcga tggtatcaaa
    18961 gagttggaca tagttttccg cacctcccca accagttcgt acatattttc tcttagcctt
    19021 taacccaggc aggatctctt caaatgtcat gtttttctcc tttaattcta cattcttcat
    19081 ttaattatag caaaaaaccg ctttatacgg ctttttgaat gtgagttatt caaacctgct
    19141 actacttacg gcaaattatt ccctgcagca agataaattt cataccattc ttttcttgtt
    19201 aagctaaagt ttgccgctcg gctaacttct ctcaagtgct taggatttgt tgtacctacg
    19261 actgcctgca tttttgctgg ataacgcaat atccaagaaa tggcaatagt tgaagaggtt
    19321 actccatatt taatagctaa acgatcaagt acttgattta aagcttgaaa tttctcattt
    19381 ccaacaaaat tccctttaaa atacccgaat tgtaagacag accatgcttg aatgaccaca
    19441 tcgtgtaatt ggcaatattc aaaaatgctg ccatctcgca tagctgcttg actatcttcc
    19501 atattaacat gaaaagctga ttcaaatcct ggagtaaaag ccgcactcaa ttgtagctga
    19561 ttaacagcta acggctgctt gacatctttt ttaagcaact ccatcatcat aggattttga
    19621 ttagaaactc caaaatctcg aactttacct tgtttataaa ggagattaaa ggcttctgct
    19681 acttggtcag attccatcaa agcatctggt cgatgaagga gcaagctatc tagatgatca
    19741 atcttcaatc tttgcaaaat accgtctact gattttataa tatagtcctt agaaaaatca
    19801 aaataggtaa attcttcaat gcgaatgcca catttggact gaatccacat cttttctctt
    19861 aaatctggac gattttttag gacaagacct aacagttctt cacaacgacc acgaccataa
    19921 atatcagcca agtcgaaggc attgattcca acagaaagtg ctgtttctac aagctcttca
    19981 acttctttta cagacttatc ttttattctc atcattccga gaacaatttc tgataattct
    20041 ttgtcatctt gaccaagagt tatgtatctc atcaaatttt tctcctttaa tttctaacat
    20101 tcttcccttc attataacaa aaaaccgctt tgcaacggct ttttgactat acttcactcc
    20161 attttatctt cttaaaccca cggaacaaga caaagattcc aataaagagg acagctaaag
    20221 gaataacttt tgtaaggaaa acatttgaaa ttcccatcca ctcataataa cggagcagag
    20281 aacccaccac aagatgggca ataatcatac tgacaaatgg acgaaagacc gcttctttcc
    20341 aattccaaat accgataact agcgaaatcg taaagacaga caaactatcc cagggagccg
    20401 gaatataaaa ggctccttct tgtatgaagc ttgccattcc tacatatcct aaaacaacta
    20461 gaagaactat agtcccaaca acaatgtaag tgccaatttt cattttagga gaatcttgga
    20521 ctaaacttct tcgtaaaatt gtggccacaa gtccaaatcc aatcagaaaa ataagaagtt
    20581 gccctaaaaa tgtgagcaaa ttgactgtta agagaggacc tttagaaaaa tcacttagta
    20641 gttgataata acgtaataca gccaggacaa gaattggcgt caaaagggac tctttgatag
    20701 aactgcgagg tgctcccttg agaatctctt tcattatttt tttaggattc ttacctagat
    20761 aatcctctgc actcatgcca tctcgttctg cttctgagaa atctagcatc atcaaataga
    20821 tctgctctct gagatagtct tcatcataga gaaatccagc aagattaaaa ctttcccaca
    20881 actcctcaaa atacttttga ttctcctcag aaaactcatg tagcaaagcg cttgtttctt
    20941 cgtaatactt cattttcttc atggtttaac ccccattctt aatcccttct actttttgac
    21001 tcaaatcgtc ccattgctgc caaaagactg agacacgctc ttctccttct ttcgttaatg
    21061 aaaaatactt ccgatctgga ccatctggcg acgggcgcat gtcgcctctt atccattgat
    21121 ttttttctaa cttttgcaac aaaggataaa tagttcctgg aacgatagta tcaaatccag
    21181 cctctcgcaa agtctgaacc aactcataac cataccgctc tttttgacca atcatatcca
    21241 agacacaacc ttcaagaaca ccttttaata gctgagtttc tttcatcact tctcccttct
    21301 aatctatttt gtaataccta ctagtaactt cacctatagt atattacttc tacactagtt
    21361 tgtaaagcat aatagttaat actcttcgaa aatctcttca aaccacgtca gcgtcgccct
    21421 accgtatgta tggttactga cttcgtcagt ttcatctaca acctcaaaac agtgttttga
    21481 gctgacttcg tcagtttcat ctacaacctc aaaacagtgt tttgagctga cttcgtcagt
    21541 ttcatctaca acctcaaaaa catgttttga gctgacttcg tcagttctat ctacaacctc
    21601 aaaacagtgt tttgagcaac ctgcggctag cttcctagtt tgctctttga ttttcattga
    21661 gtataaataa aaaaacagaa ctagtctgaa ctagtcctgt ctacttttac ccaatcacac
    21721 ttccatttgg tacagctgga tcaactgtga gaagggttaa tttgccatca tattcagctg
    21781 atagaatcat accctggctg acatattttt tcatcatttt acgtggtttg aggttagcaa
    21841 cgatttgaac tttcttgccg accaattctt gttcatttgg atagtatttt gcaattcctg
    21901 aaagaatctg acgatcttct ccatcaccag catccaagcg gaattgaagc aacttatctg
    21961 aaccttctac tttagacact tctttgactt ctgcgacacg gatttcaacc ttgtcaaagt
    22021 cttcaaactt gatttcatcc ttgtttagtt tgagctcaac ttcgtccgga ttccattctt
    22081 tttcgactgc tggtttattg ccttccattt gttccttgat ataggcgatt tcttcttcca
    22141 tatttagacg tggaaagata ggtgttcctt tggcaactac agtcacatct gctgggaagt
    22201 cagccaaact caagttttca agactagaaa cttcttccaa accaagttga gtcaaaactg
    22261 cacgactagt ttccatcata aatggttcaa tcaagtgagc aactacacga atgctggctg
    22321 ccaagtggct catgacactt gccaattggt cacgaagagc ttcatccttg gccaagaccc
    22381 atggtgcggt ctcatcgatg tatttattgg tacgagagat cagagtccag actgcttcaa
    22441 gcgcacgtgg atagtcaact gcttccatgt gtgtatggaa gtctgcgatt gattgttctg
    22501 caacctcagc aagaacatga tcaaattcag tcacaccttc tacataggca gggatttgtc
    22561 catcaaagta cttattaatc atggaaaccg tacggttaag gaggttccca aggtcattag
    22621 ccaattcata gttgatacgg ccgacatagt cttcaggagt aaaggttccg tctgaaccaa
    22681 ctggaaggtt acgcatgagg tagtaacgaa gtggatctag tccataacgc tctaccaaca
    22741 tttcagggta aacgacattc ccttttgact tagacatttt tccgtctttc atgacaaacc
    22801 aaccatgggc aatcaaacga tcaggtaatt taacatccaa catcataaga aggattggcc
    22861 agtagataga gtggaagcga aggatatctt ttcctaccat atggaagact gttccattcc
    22921 agaacttgtc aaagttacca tgttcgtctt gagcgtagcc aagagctgtc gcatagttaa
    22981 gaagggcatc aatccaaacg tagacaacgt gttttggatt tgatgggaca ggcactcccc
    23041 atgtaaaggt tgtacgagat accgccaaat cttccaagcc tggctcgatg aagttgcgta
    23101 gcatttcatt aaggcgacca tctggcgtga taaattcagg atgagctttg aaaaattcga
    23161 ccaaacggtc ttggtatttg ctaaggcgaa ggaagtatga ttcttcagaa acccattcaa
    23221 cctcatgacc tgatggagca ataccaccag tcacatttcc agcttcatca cggaaaactt
    23281 ctgccagctg gctttctgta aagaattctt cgtctgatac tgaataccaa ccagagtatt
    23341 cacccaagta gatatcatct tgagcaagta agcgttcaaa gacctgtgcg acaacttttt
    23401 catggtagtc atcggttgta cggataaatt tatcgtatga gatatctagt aattgccaga
    23461 gttctttaac tccaaccgcc attccatcaa cataggcttg aggtgtaata ccagcttctt
    23521 ccgctttctg ctggattttc tgaccatgtt catcaagacc tgtcagataa aatacatcgt
    23581 agcccatcag gcgtttgtaa cgtgctagga catcacatgc gatagttgtg taggcagaac
    23641 cgatatgaag tttcccagat ggatagtaaa tcggcgttgt aatataaaaa tttttttcag
    23701 acataatttt tcctttccag gcaaatgaaa cctgtttttc taacacttca ttatatcaca
    23761 tttttaatga atttcgatag ggaaatccat acaaaaacaa gatagacgag tgtccatctt
    23821 gttgatctca ttcataacga agggcttcaa ttggatcaag tttcgatgcc ttgttggctg
    23881 gcaagactcc aaaaatcata ccaacactag ccgaaactgc aagactaaat agggcaactg
    23941 ggattgatac tccaacttct ataccttcta ttaaaccttg cagtaacaaa cctgctaagg
    24001 cagttaaacc acttgcaatt gtcaagccaa ttaagccacc taacaaggtc aaaatcatgg
    24061 attcaatcaa aaactgaatt aaaatattgg cacgtgttgc acccaaagct ttacgaagac
    24121 caatctcacg agtgcgctct gtcaccgaaa ccagcatgat gttcatgaca ccagttcctc
    24181 caacaaagag agaaatccct gcgatggaac taataatcgt cgtcataaaa ctaaacgatt
    24241 gttgaatttc tgcaaataca acggactcat ctgccacctg gtattctccc tgttgtaagc
    24301 ctgcaagctc tgtcattttt cgtgccagtt ctggacccag agttggggtt aaactggtat
    24361 cattcactcg aaagacaata ctagctattt catctatatt aaaattcgca gcaagggaga
    24421 tattggtagt aataggcaag ccaccaaacc catatatttt tgacttttta gcctccggac
    24481 tagtataaac cccaatgacc cggtaactaa atccattgac ttctacaacc ttgttaatag
    24541 cctcttgagg agattcaaat aaactaatgg acaattcctc atctagcaaa ataacacttg
    24601 caaactcttt gaaatcttgc tctctcagac tacgacctgc aataatttca ttcttaacag
    24661 cgtccatgta agttctgttt ccacctgtca aattagcatt ctcaaccttt ttatcttgat
    24721 aggtcaagat ggcattcgtt gaattggtta catagtaact atccactccc ttcagtttag
    24781 ctgcctcttg aacccaggat tcttgcggtt ttggcggttc aacaggaact tcctcttcct
    24841 ttccagaaac cgtaaaagct gattgtttct gagtaaaaga cccatcttta ctttttttag
    24901 gagagaaaaa gacgctaata tttttctgag atttagtcat atctttattg acttgacgag
    24961 atagggaatc acccaaagcc ataatcacaa caactgatga aacaccgata ataatcccaa
    25021 tcatagtaag caaagaacgc atcttgtgag ccatgataga tgaaaaggca aatttcagat
    25081 tctgcatctt agttttcctc ctttcctaac tgagcactgt cagacgaaat gaccccatcc
    25141 cgaatgacaa tctgacgttt ggcataggca gcaatctcag gctcatgcgt taccatgata
    25201 atggtttttc cttctttatt caaatcaacc aataattgca taatttggtt acctgttttg
    25261 gtatccaagg ctcctgtcgg ttcatccgct aggataatag aaggattgtt taccaaggca
    25321 cgcgcaatgg ctacacgttg cttttgacca ccagataatt ctgaaggtaa atggtgacta
    25381 cgttctgtca attcaacctt gtctaaatat tcctcagcca acttgcgacg ttttgaagac
    25441 gaaactcctg cgtaaatcaa gggcaattct acattttgca gagcattgag cttcgataga
    25501 agaaagaact gctgaaagac aaaaccgatt tgttggttac ggaccttagc tagttgtttt
    25561 tcaccaagcc cagccacttc ttgaccttca agataatatt ctccactggt tggtgtatcc
    25621 aacatgccaa tcgtattcat cagagtggac ttaccagacc cagatggtcc catgatggct
    25681 acaaattcac cctcattcac ttctagattg atatttttga gaacctgcag ttcttggtca
    25741 ccattacggt aacttctgaa gatatttttt agactaatta gttgcttcat cagccttcac
    25801 ctcttttcct tcttccaagg aagatgttgg attactgatg accttagcac cgttcgttaa
    25861 accagaagtg atttcttgat tttctgcgtc agcatttccc aatgaaacct caactttttt
    25921 agccttttgt tgttcatcca caatccagac ataattttta ctatcatcca ttactagact
    25981 gctaacagga ataagaatag ccttagtttt gcttttaacc tcaatgttga cagaaaaacc
    26041 ttgtttcaaa tcaccaacct cgcctgtcac atcaatagta taagggtatt tagaacctgt
    26101 attattcccg gctgctggac tagctgcttc accattgttt ttaggatagt cagaaatata
    26161 gcttaatttc ccagtccatt ttttatcagg atacacttta gaagtaaagc ttacttcttg
    26221 acctacagaa aggttggcta gattgtactc agacaattct cccttgactt gtaaattttc
    26281 attgctgaca atatgaacca taacttgact cgcccctgtt ggagatttag aaacattgct
    26341 attgacttcg actacagttc cctctagggt actgagaaca gttgttgcat ccaattgact
    26401 ttgagccttg cttaattgcg ctgcagcatc tgcacgcgca tcacgggcat cacccaattg
    26461 agcatcaata gaagcaacag aatttccagc cactggagtt gggctttgca ccgttgcatc
    26521 ttctcctcct actggcgctg gtaactgtgg agcctgagct gaagcggctt catttcgtgc
    26581 ttgattgagt tcattgatat gacgatctgc cttagctact gctcgactag ctgaatcata
    26641 ggccgcctgc gcttctgaac tactgtactt gactaaagcc tgcccttcgc tgaccttatc
    26701 gcccacagaa acaaggattt catctaaatc acccttacta gcatcaaaat aaacatattg
    26761 ttcatttttt gctgttactg tccctgacaa taaaacagag gatgccacgc ttccttcctt
    26821 ggcaacaaca agatgagtag gctcatcttt tacagcagtc tgagaaggtt gtctaaaaag
    26881 taaaatcccc ccggcaccca atacaactac actcgcagca ccgattgctg catacagttg
    26941 ccacttttta gctttaccat tctttttctt cataatgaaa ctccttttct tttttacaat
    27001 actttgctat tataccaaat ttccctccag caaacaatgc agttcagatg gaaataatgg
    27061 cagttcagga ttaaacaatc gttcggaatt ttgcttttct attgtactag atatataata
    27121 cactatcttg acttatttgg caagcttttt tgcaattttt tgtgcgtagc agatttttgc
    27181 aatcaaatca aaaaaagaat aaaatataac tatcaaaaaa gacactctac tatttaaaag
    27241 attacaaagg agttttcaat gagagaatat gatatcattg ctatcggtgg aggtagcgga
    27301 ggaatcgcta ccatgaaccg tgctggtgaa catggagcca aagcagccgt tattgaggaa
    27361 aagaaattag gtggaacctg tgtcaacgtc ggttgtgttc ctaaaaaaat catgtggtac
    27421 ggggcgcaaa tcgctgagac tttccatcaa tttggagaag actacggctt taagactact
    27481 gatcttaact ttgactttgc aaccctacgt cgcaatcgtg aagcctacat tgatcgcgct
    27541 cgttcttctt atgatggtag ttttaaacgc aacggtgtag acttgattga aggtcatgct
    27601 gaatttgtag attctcatac tgtaagcgta aatggtgaac tgattcgtgc taaacatatc
    27661 gtgattgcta caggtgccca tccaagtatt cctaatattc ctggtgctga gctaggtggc
    27721 tcttctgatg atgtatttgc ctgggaagaa cttccagagt caattgccat tctaggcgct
    27781 ggttatatcg ccgttgaatt agctggcgta ctccacactt ttggtgtcaa gacagatctc
    27841 tttgttcgcc gcgatcgtcc tttacgtggt tttgattcct acatcgttga aggtttggtc
    27901 aaggaaatgg aaagaacaaa cttaccactt cacactcaca aagtccctgt caagttagaa
    27961 aaaactactg acggcattac cattcatttc gaagatggta ctagtcacac agctagccaa
    28021 gttatctggg ctacaggtcg ccgtccaaac gttaagggct tgcaacttga aaaagctgga
    28081 gtgactctga acgaacgtgg ctttatccaa gtggatgaat accaaaatac tgttgttgag
    28141 ggaatctatg ctctaggtga tgtaacgggc gagaaagaac tgactccagt tgcaatcaag
    28201 gccggacgta ccctatctga acgtctcttt aacggaaaaa ctactgcaaa aatggattac
    28261 tcaactattc caactgttgt cttttcacac cctgctatcg gaactgttgg tttgacagaa
    28321 gagcaagcta ttaaagaata cggtcaagac caaatcaagg tttataaatc aagctttgca
    28381 tctatgtact ctgcttgcac tcgcaaccgt caagaatccc gtttcaaact cataacagct
    28441 ggttcagaag aaaaagttgt cggacttcat ggaattggct acggcgttga tgaaatgatt
    28501 cagggatttg ccgttgctat caaaatggga gcaaccaagg ctgactttga tgcaactgtg
    28561 gcaattcacc caactgcatc tgaagaattt gtaaccatgc gttaatcgaa acaaaagaag
    28621 ctgatataaa tatgtctgct tcttttt
//
LOCUS       DAVAZT010000027        27275 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVAZT010000027 DAVAZT010000000
VERSION     DAVAZT010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27275
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.027"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            228..1910
                     /locus_tag="VQT45_001096"
     CDS             228..1910
                     /locus_tag="VQT45_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2359429.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNMSIS
                     KGQVQLQNELVKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHRKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            1895..2725
                     /locus_tag="VQT45_001097"
     CDS             1895..2725
                     /locus_tag="VQT45_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET2359430.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVASLLLSLQNQGRFYNPWK
                     "
     gene            2918..3421
                     /locus_tag="VQT45_001098"
     CDS             2918..3421
                     /locus_tag="VQT45_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HET2359431.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     regulatory      3475..3709
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            3874..4437
                     /locus_tag="VQT45_001099"
     CDS             3874..4437
                     /locus_tag="VQT45_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2359432.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTVAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYILLKPTLKHYER"
     gene            4451..5077
                     /locus_tag="VQT45_001100"
     CDS             4451..5077
                     /locus_tag="VQT45_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET2359433.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRSLTRLIDIPVIITWVVIIAFVFYRKRWKIESFFMLGNLTLAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGALFIEFPFYDKLRFQWRFKGKQK"
     gene            5189..6061
                     /locus_tag="VQT45_001101"
     CDS             5189..6061
                     /locus_tag="VQT45_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000525616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2359434.1"
                     /translation="MGMLLATRLKNKRKELKLSQKELAEGICEQGQISRMEQGKYSPG
                     SELLFQLSKRLKVSMDYFFEDTEVSSLENIDKFKELSKKFLDEREYESLHYIYELEKS
                     KRARLSAKDQIYLDWIDTLVQFCYLNHQTGAVAKLEKILLSLKKSDFYYLQLGNTLAN
                     FYFDMGQEDTYQELYQLLKENLQSLSVHHLEQLELMIKFRYNYCRYLWLNERTSEAIE
                     EITETIAICKRYNSSYRLADLYCLLGSISEGFAERDRILGFYQVSYQLYKHEENQRMM
                     LEIEKEMKLLESED"
     gene            6191..6328
                     /locus_tag="VQT45_001102"
     CDS             6191..6328
                     /locus_tag="VQT45_001102"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359435.1"
                     /translation="MKRSQVVKRCILIALLLLFLLNVLSGSLSVTTRGVDPRPAYGVS
                     L"
     gene            6752..7666
                     /locus_tag="VQT45_001103"
     CDS             6752..7666
                     /locus_tag="VQT45_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000781144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HET2359436.1"
                     /translation="MKLYQINDGIQIFESSNLEKIVIRNYRNGKKITIDHQPLLKKLL
                     LFLEVPKREEEILLYLPELSNKTLRSVLTNFMSLNIIHCQDTLIIHKKINILIIGLGT
                     TGGYLADGLCRSNINSKLFLLDKDRVDETNVGRQIYLRDDIGQYKVDVFKQKFSDKEI
                     KVFKIFINSKKDLEKICKREGIDLVIQCGDSPSPRELGKIVNTVCDTLQIPYIVNTGY
                     MSNVVPLPEFYYPNNRYNFNYKHQFSDEKLLFSQVLSKADYMVAIQSSFVMLMQIKNF
                     IFNEEPIYYGYRGYYNSVTLAWEVEKID"
     gene            7659..8672
                     /locus_tag="VQT45_001104"
     CDS             7659..8672
                     /locus_tag="VQT45_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359437.1"
                     /translation="MTKYLELDYSHSYILEGFRKNDAFIENHKECLDMLSDKIWRDNK
                     YMNTEKNISSPTRTILSRYTCNILSSLFIDISKNSIEKLIVTCENSDLNWIYNYYKSV
                     YNGVFCELRQLIQQYCKVKDKYEKWLFIKAIINQGIRQNEKEVVEFFLKQLKDNNQGI
                     FDYINSFSFYLLKFYSKDKSRIFLEEQLDIDDFLGSDKEDYARSLVFKNYASLLPDTS
                     ELKRNIMEKCLSQTPQDTDLWKEWFETYASQKEIRQKATEIFKHGYSDISLLKLVKIE
                     PDDTESLIRMIILCTSDLNSNIARYLISFLSDGRLKEFLELFVENFDFLNIIEGKTSE
                     INF"
     gene            8656..10248
                     /locus_tag="VQT45_001105"
     CDS             8656..10248
                     /locus_tag="VQT45_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001236730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2359438.1"
                     /translation="MRLIFRIIRKDIILYSILTFLLSIAMVSEAFLMQFIVDSIKFGE
                     KKYVLISIFIVIFLILQTLLYYYQQFLTAVLSKKSAYEYRKLIFKNIQQTSLRLVTGE
                     KNDSILASLTTQIDQIEYNYFYSVYWGGYLLCQLVVAIVMSLYLNPLMSVLTICLSLP
                     NLFVALLFKNSLEQKQEELINETNSSIAVTQDLIEGITDWKIANREPNIFRVFESKTL
                     KLLEKQVKVEKFQYIVVSLNQLFSNVLYFGSWIVGGFLIIRGQLSLGSLIAFSQLLAR
                     ISYPVYASSDLLSKYISGKKIVEILSKEFIFSDESRNYPDEFNVISFEHYFTNIDEKD
                     MPFDKEFYKNKKYLLKGKSGSGKTTILKSILREYDDYSGIVKINGVDVRDIKESVLFD
                     NIAYVSQKPHLFSASLRDNLTLFSEDFTDNEIVEVLKFVELSKWANKDCLDMMLSNDD
                     IKLSGGEVKRVSLARALLMNKNILLLDEFSAGIDYETLLKIEKKLIDLDKMIIYVTHV
                     DIDRSGKQFDDVIDLDCLFISS"
     gene            10440..11343
                     /locus_tag="VQT45_001106"
                     /pseudo
     CDS             10440..11343
                     /locus_tag="VQT45_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091364.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            11361..11498
                     /locus_tag="VQT45_001107"
                     /pseudo
     CDS             11361..11498
                     /locus_tag="VQT45_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
     gene            11526..11867
                     /locus_tag="VQT45_001108"
     CDS             11526..11867
                     /locus_tag="VQT45_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359439.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLKNHI
                     LPLWIGMVSFF"
     gene            11840..12151
                     /locus_tag="VQT45_001109"
                     /pseudo
     CDS             11840..12151
                     /locus_tag="VQT45_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            12279..12866
                     /locus_tag="VQT45_001110"
     CDS             12279..12866
                     /locus_tag="VQT45_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HET2359440.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            13256..14863
                     /locus_tag="VQT45_001111"
     CDS             13256..14863
                     /locus_tag="VQT45_001111"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HET2359441.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(15422..17053)
                     /locus_tag="VQT45_001112"
     CDS             complement(15422..17053)
                     /locus_tag="VQT45_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HET2359442.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGITITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            17346..22325
                     /locus_tag="VQT45_001113"
     CDS             17346..22325
                     /locus_tag="VQT45_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HET2359443.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVAIASETASPASNEAATTE
                     TAEAASAAKPEEKASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEK
                     EVQPDVPKNTEKTLKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNE
                     KASKEAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDA
                     GHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFI
                     NQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYN
                     YQFMQPEGDKVPADNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKT
                     KVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGD
                     KDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWR
                     WWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVA
                     HKGGKGSKVYMAFSTTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFF
                     EHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADF
                     YEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTT
                     FDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSA
                     QLSGSVDIRLTKPRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEV
                     RGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMA
                     KAAARSLGNNKVQVGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQ
                     SGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLR
                     VQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEAS
                     PKTILGIEVSQEPKKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQK
                     TGRQTLTLRYQGHEVNFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEA
                     FLKAIEAAEQVLKDHETSTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQ
                     ELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVF
                     SDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVD
                     LSYASIVKIPIEKDKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESA
                     EKPQPAKPAPQNKVLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRV
                     IIQGRDGLLRHVFEVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQ
                     NTAVKSEEASKQLPNTGTADANEALIAVLASLGLASLALTLRRKREDKD"
     gene            22415..23611
                     /locus_tag="VQT45_001114"
     CDS             22415..23611
                     /locus_tag="VQT45_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HET2359444.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            23747..24274
                     /locus_tag="VQT45_001115"
     CDS             23747..24274
                     /locus_tag="VQT45_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET2359445.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETILYVFVRVLETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            24351..24707
                     /gene="glnR"
                     /locus_tag="VQT45_001116"
     CDS             24351..24707
                     /gene="glnR"
                     /locus_tag="VQT45_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HET2359446.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            24744..26090
                     /gene="glnA"
                     /locus_tag="VQT45_001117"
     CDS             24744..26090
                     /gene="glnA"
                     /locus_tag="VQT45_001117"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HET2359447.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(26186..26305)
                     /locus_tag="VQT45_001118"
     CDS             complement(26186..26305)
                     /locus_tag="VQT45_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HET2359448.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            26793..27275
                     /locus_tag="VQT45_001119"
                     /pseudo
     CDS             26793..27275
                     /locus_tag="VQT45_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         8594 a         4569 c         5792 g         8320 t
ORIGIN      
        1 aaccatacct acggcaaggc gaaactgacg tggtttgaag agattttcga agagtataaa
       61 atgatgggga aggctgggca actagtcttt ttcgatgttt atagattagt taggcaagta
      121 agctaggata ggaatctttt tggtgctaag attttaagag aagagactgc aagaagggct
      181 tgatttatga taaaatagaa gtctaagaag cgaatgaaga gagtaagatg aaagaagcta
      241 taattgagtg gaaggatttc tctttccggt atgaaacaca acaagaaccg accttgcaag
      301 ggatagactt gaccatttac aagggagaga aagtcttaat tgttggacca tctggatcag
      361 gtaaatctac cttgggtcag tgtttgaatg ggattattcc caatatttac aagggtcaga
      421 catatggaga atttttgata aagggtcaaa cagcctttga tatgagcatc tatgataagt
      481 ctcatctggt tagcacagtt ttgcaggata cagatgggca gtttattggc ttgtctgtgg
      541 cagaagattt ggcgtttgct ctggaaaatg atgtgacagc cctagatgag atgaaaggtc
      601 gtgtttataa atgggctgaa aagctggacc ttcttccttt actggatcag cgtcctcagg
      661 atttgtcagg tggacaaaag cagcgagtca gtctggctgg tgtcttgatt gatgaaagtc
      721 cgattctctt gtttgatgag ccactcgcca atctagatcc caagtcaggt caggatatta
      781 tcgaattgat tgaccagatt cataaggaag aggggacgac gactcttatt atcgagcacc
      841 gtttggagga tgttctgcat cgccctgtgg atcggattgt cttgataaac gatggtcgta
      901 tcctttttaa tgggagccct gaccagttgc ttgcgactga tttattgact caaaatggaa
      961 ttcgagaacc cctttatcta accactctcc gtcaattagg tgtggactta gtcaaggaag
     1021 aacagttagc gaatctggat aacatgtcta tctcaaaagg tcaggttcag ctgcagaatg
     1081 aactggtaaa agaaactcca gaattgcagt cactctttaa attagaggac gtgtctttct
     1141 cttatgatga tagaccgatt ttaaaatccc tacatttaga tattaaaaag ggtgaaaaga
     1201 ttgctattgt cggaaaaaat ggagcaggga aatcaactct agccaaggct ataagtagct
     1261 ttattcagac ggaaggacgc tatctttggg aaaaacagga tataaaaggc gattctgttg
     1321 cagagcgggc ggaacgagta ggctatgtgc tacaaaatcc taatcaaatg atttcaacca
     1381 atatgatttt tgatgaggtg gctctagggc tccgtttgcg aggtgtggat gagaaggaaa
     1441 ttgaaacgag agtctatgaa accttgaaaa tctgtggact ttatgaattc cgtaattggc
     1501 ctatttctgc cctgtcattt ggtcagaaaa aacgtgtcac cattgcttca attttggtct
     1561 taggagctga aattattctc ctagatgaac cgactgcagg tcaagatcag aagaactata
     1621 ctgagattat ggaatttctc gaagagttac atcgaaaagg gcataccatt gtcatgatta
     1681 cccatgatat gcaattgatg ctggattatt cagaccgagt ccttgtcatg gtggatggag
     1741 aattgattgc cgatactgtt ccagccagtc tgttgagcga tcctgagctg ttagtaaaag
     1801 ccaatctaaa agaaacctcc atctttaact tggctaagaa actagatgtg gatccactgg
     1861 atttaacggc attttacaaa gaaaggagag agggatgcaa gctaaattaa tcggttacca
     1921 gcatagagat actgtgattc atcgcttgtc aggagctggg aaacttctct ttttcattct
     1981 ggtatcattg gcggccatga ttagctatga taccagaatg ctcttgctga ttgccatctt
     2041 ttcagtcttt ctcctctatt tatcagaaat tcgctttaaa gatgtttcct ttgtagccgt
     2101 ttttgcgacg gtatttgccg ttttaaacgt tttgatggtc tatctctttt ctcccgagta
     2161 tggggttgga ctttatggag agagaagtgt gatttggcag ggaatcggtg tctacactct
     2221 aaccagccag gagctctttt atctgctaaa tttggccatt aagtatcttt gcaccattcc
     2281 tctggctatt atctttttga tgacaaccca tcctagtcag tttgcttcca gtttaaatca
     2341 aattggtgtg ccctataaga ttgcttattc tgtcagcctg accttgcgct atattccaga
     2401 tttgcaggaa gaattcttta ctatcaagat gtctcaggag gcgcgtggga tggaattatc
     2461 caagaaagct tctcttatgc aacgaatcaa aggcaatctg ctcattatta cgcccttgat
     2521 ttttagctcg ctagaacgca ttgataccat tgcgactgcc atggagcttc gccgctttgg
     2581 gaaagaaaaa aaacgcacat ggtatagtta tcaggccttg aaaaaaggag actatattac
     2641 cttgctcttg gcaaccttgt ttttagtagc tagtttacta cttagcttgc agaatcaggg
     2701 acgattttac aacccttgga aatagcttga aaaaattgaa aaaatcaagt cgtttctatt
     2761 gacaatgatt ctgaaagtgt tatactaaga aagtagtttc gctgatttac ttcaaacctg
     2821 ttgtgaggta agttaacgat gccttaacca cgctgtttgc tgagcttgac tccgggcagt
     2881 gtggctattt ttttgcaatg gtgaaaggaa gcaagtcatg acaaatcaca ttgtattatt
     2941 tgaacctcaa attccacaaa atacgggcaa tatcgcgcgt acttgcgctg cgaccaattc
     3001 tcccctccac atcatcaagc ctatgggctt tcctattgat gaccgcaaga tgaagcgggc
     3061 tggattggat tactgggata agctagagat ttatttttac gagagtttgg aagatttcat
     3121 atctcagatg aagggaaaac tctatctgat ttcgaaattc gcggaaaaag tctattctga
     3181 ggtggattta tcgactgacg aggaccatta ttttctcttt ggacgtgaag acaagggctt
     3241 acctgaagat tttatgcgag aacatcctga gaaggctctc cgtattccca tgaatgatga
     3301 acatgtccgc agtctcaatg tgtctaatac cgtctgcatg attgtctatg aggctcttcg
     3361 ccagcagaac tttgcaggtc ttgaactcgt ccatacctat gaagtggata aattgaaata
     3421 aaaaatgaaa atgaacaaaa tgcttgcgct tgcaagcgtt ttttgttatg ataaaagagt
     3481 cttcagggca gggtgtgatt cccgaccggc ggtgacttta actaggaaat gatcttttcc
     3541 ttttatactt tgttgacaag ctttgcctaa ccagaagtta tgcctacagc ttgtcgccta
     3601 gtctaaaaga aaaatctcta tttccttctc tttaaagaag tccgcgagcg caagctgatg
     3661 tggtgagatt ccacaaccga cagtatagtc tggatgggag aagacgaaag aatagctttg
     3721 tctgttttga tagatttata gccggattgt aaccacttgc tttgtttttc tttaatagag
     3781 taggagggaa cttttgggat ataaaaagtg agaatagata gaggaatcct ttccaacttc
     3841 ttctgatttt atagaaaatt ggaggaacct gttatgacaa acacacgtcg actttcgacc
     3901 attgcaattt tatcagccat ctcatttgtg ctgatgtact ttgactttcc gcttttacca
     3961 gcggcatctt tcctcaagat cgaatttagt atcttgccag tccttgtggg tctggtggtc
     4021 atggatttgc ctgctgctct aggagtgctc ttgcttcgct cactcttgaa attgcttctt
     4081 aacagccaag gagtgaatac ttacattggt ttgccgatga atatcgtagc tttgggagtt
     4141 tttgtcatcg tatttgcttt gatttggaaa aaggaacgga caacccttcg tttcctacta
     4201 ggctctctag ctgggactat tggtttaacc gtggctatgt tagttctcaa ctatgtttat
     4261 gctgttcctt tgtacgctaa gtttgctaac tttgatattg gaaaaatttt gggactttcc
     4321 aactacctaa tgaccatggt attacctttt aacttgattg aaggtgtaat cttttccgtt
     4381 tcattctggt tgttgtacat tctcttgaaa ccaaccttaa aacattatga aagataaaca
     4441 aacattttta atgaagggca gttttgccct tttacttttc gttattcttg gctatatggt
     4501 caaattttac cctgaaatgt tggtcaattt tgaccaatcg attcagactg ccattcgagg
     4561 agacttacca gattatttga ctattctttt tcgatccctc acacgtctga ttgatattcc
     4621 agtgattatc acttgggttg tcattatagc ttttgtcttt tatcgtaagc gatggaagat
     4681 agaaagtttc ttcatgctgg gaaatctgac tttggcaggt cttttaatcg tgacctttaa
     4741 aaatatctac cagcgcccac gaccagctat cttacatctg gtggaggaga agggattttc
     4801 cttcccaagt gggcattctc tggctgtaac gctgatggta gggactttga ttgttattct
     4861 tagtcagcgg attaaagatc aggtctggag aaaaatcgta caaatcgtcc ttggcctcta
     4921 cctagtcagt gtgctggtat caagagtcta tctgggagtt cattacccat cagatgttct
     4981 tgccagtctc tgtgtgggct tgggagccct gtttatcgag tttccctttt atgataagct
     5041 ccgcttccaa tggcgattta aaggcaaaca gaaatgatgg aaaagataaa aaattgtaca
     5101 aatacaaata gaaccatatg aaatatatac ttgaaacatg ttttggagtt tgatatattt
     5161 taataaataa agcaaggagg aagaaagtgt gggtatgtta ttagcgacac gcttaaaaaa
     5221 taaaagaaag gaattaaaat tatctcaaaa agaattagct gaggggattt gtgagcaagg
     5281 gcagattagc cgtatggagc aaggtaaata ctcacctggg tcagaattac tctttcaact
     5341 atctaagcga ttgaaggtga gcatggatta tttctttgaa gatactgagg tttctagttt
     5401 agaaaatatt gataagttta aagaattatc taagaaattt ttggatgaga gggaatatga
     5461 atctctccat tacatctatg aactggaaaa atctaaacgt gctcgtctat ctgctaaaga
     5521 ccagatttat ttggattgga ttgatacatt agttcaattc tgttatttaa atcatcaaac
     5581 aggggcagtt gcgaaactgg aaaaaatact gttatctctg aaaaaatctg atttttacta
     5641 tctacaactg ggaaatacct tggctaattt ttattttgat atggggcagg aagacacata
     5701 tcaggaactc tatcaacttt taaaagagaa cctccagtca ctatctgttc atcatttgga
     5761 acagttagaa ttgatgatta aattccgata taactattgt agatatttgt ggttgaatga
     5821 acgaacatct gaagctatag aagaaattac agaaacgata gctatttgta aaagatataa
     5881 tagtagttat cgattagcag atttgtattg tttattggga agtataagcg agggctttgc
     5941 tgaaagggat aggatactag gtttttatca agtatcttac cagctttaca agcacgaaga
     6001 gaaccagaga atgatgctag aaattgagaa ggaaatgaaa ttattggaaa gtgaagatta
     6061 agcaaaaaga tttgtattct tagataactt taatacatat tataaaaaaa ataaaaaaat
     6121 atcataaaaa ttattgacaa accaaaattg atgtgttaga atatcaccaa tagttaagga
     6181 ggtttagaag atgaaaagat ctcaagttgt caaacgatgt atattaattg ctttattgct
     6241 tctatttcta cttaatgtgt taagtggttc tttatctgta acaactagag gagttgatcc
     6301 aagaccagca tatggagttt cgctttaaag ttgtgcatag ttcttctttt atagacggag
     6361 agtttttctc aatagtaagt gattcaaatt ttgatggatg attttccatt aaattaagtg
     6421 attgcgaaaa ctttttgaaa tacattctct ttggatattg aaagtttgtt ttggattttt
     6481 ttatgaagct tatcttagct gttagattgg ggttttatgg gatttgtcct caccgggaaa
     6541 aaatcttaaa tctttgaaga aagaggtttt tatcttatgg ttagagatac atcagaagaa
     6601 attgaagtta ttgacttgtc ttctatgacc gtttcctact catctgttat gctaggaaac
     6661 tcttggatga cgtggaattg atttattaag atagattatt tggtttttac caaaaatctg
     6721 tctttttaat ttttaaagga ctaatggtga tatgaaacta tatcaaataa atgatgggat
     6781 acaaattttt gaaagtagta atcttgaaaa aatagtaatt agaaattata ggaatggtaa
     6841 gaaaataact atcgatcacc aaccattatt aaaaaaatta ctactattcc ttgaagttcc
     6901 taaacgtgaa gaagaaattc tattatatct tccagaatta tcaaataaaa cattacgaag
     6961 tgttttgacg aattttatga gtttaaatat aattcattgt caagatacat taataattca
     7021 caaaaaaata aacatattga taataggttt agggactacg ggtggatatc tggcagatgg
     7081 gttatgtcgt agtaatatta attcgaagct atttctttta gataaggatc gtgtagatga
     7141 gactaatgta ggtagacaga tttatttaag agatgatatt ggtcaatata aagttgatgt
     7201 atttaaacaa aagtttagtg ataaagaaat aaaggtattc aaaattttta ttaatagtaa
     7261 gaaagatttg gaaaagattt gcaaaaggga gggtatcgat ttggttatac aatgtggtga
     7321 ctccccttca cctcgagaat taggaaaaat tgtgaataca gtatgtgata ctctccagat
     7381 accttatata gttaacactg gctacatgag taatgtagtt cctttgccag aattttatta
     7441 tccaaataat agatacaatt ttaattataa gcatcaattt tcagatgaaa agttactgtt
     7501 ctcacaagtt ttgtctaaag ctgattatat ggtggcaatt caatcatcat ttgtaatgtt
     7561 aatgcaaata aaaaatttta tatttaatga agaacctatt tattatggtt ataggggata
     7621 ctataattct gtaacattag catgggaggt ggaaaaaatt gactaaatat ttagaattgg
     7681 attattctca ttcatatatt ttggaaggtt ttagaaaaaa tgatgcgttt attgaaaatc
     7741 acaaagaatg ccttgatatg ttatcagata agatttggcg agataataaa tatatgaata
     7801 cagaaaaaaa catatcatca ccgacacgaa caatcttatc acgctatact tgtaatattt
     7861 tatcgtcttt gtttattgat attagcaaaa atagcataga aaaattgata gtgacatgtg
     7921 aaaatagcga tcttaattgg atttataatt attataaatc ggtttacaat ggagtatttt
     7981 gtgaattgcg acaacttata caacagtact gtaaggtgaa ggataagtat gaaaagtggc
     8041 tttttataaa agctattata aatcaaggta ttcgtcaaaa tgagaaagaa gttgttgaat
     8101 tctttttaaa acaattgaag gataataatc aaggtatttt tgattacatc aatagtttta
     8161 gtttttatct attaaagttt tattcaaaag acaaatctcg cattttttta gaagagcagc
     8221 tagatataga tgattttttg ggatcagata aagaagatta tgctaggtct ttagttttta
     8281 agaattatgc ttctctattg cctgatactt ctgaattaaa aagaaatatt atggaaaaat
     8341 gtttaagtca aacacctcaa gatacagatt tatggaaaga atggtttgaa acttatgcca
     8401 gtcagaaaga gattagacaa aaagcaacgg aaatatttaa gcatggttat tcagatattt
     8461 cgttactaaa attagttaaa attgagcctg atgacactga gagtttaatc agaatgatta
     8521 tcttatgtac cagtgaccta aatagtaata ttgcaaggta tttgatttca tttttgagcg
     8581 atgggcgatt aaaagaattt ttggagttat ttgttgaaaa ttttgacttt ttgaatatta
     8641 ttgagggaaa aactagtgag attaattttt agaataatta gaaaagatat tatattatat
     8701 tctatattaa catttttgct atcaatagcg atggtaagcg aagcattttt gatgcaattt
     8761 attgttgatt caattaaatt tggtgaaaag aagtatgttt tgatttctat ttttattgta
     8821 atttttttga ttcttcagac tttattgtat tactatcaac aatttcttac agctgtatta
     8881 agtaaaaaat ctgcatatga gtaccgtaaa ttaattttta aaaatattca gcagacttct
     8941 cttaggcttg ttacaggtga aaaaaatgat agtattctag cttctttgac aacgcaaatc
     9001 gatcaaatag aatataatta tttttattct gtttattggg gtggatattt gctttgccaa
     9061 ttagtggtag ctatagttat gtcgctttat ctaaatccat tgatgtctgt attaaccatt
     9121 tgcttaagtc tccctaattt atttgtagca cttcttttta aaaactcctt ggaacaaaag
     9181 caagaagagc taattaatga gacaaattcc tcaatagcag ttactcaaga tttaattgag
     9241 ggaattactg attggaaaat tgcaaataga gaacctaata tatttagagt gtttgaaagc
     9301 aaaacattga agcttttaga gaagcaagtg aaggtagaaa aatttcaata cattgttgtt
     9361 agtttaaatc aattgttttc aaatgtttta tattttggta gttggatagt aggtggattc
     9421 ttgattatac gggggcaact ttcattaggg agtttgatag cgttctctca attattagca
     9481 agaatttctt accctgttta cgcttcttcg gatttattgt caaaatatat tagcggtaaa
     9541 aaaattgtag aaattctttc taaagaattt atattttcag acgaaagcag aaattatcca
     9601 gatgagttta atgttatttc atttgaacat tattttacaa acattgacga aaaggatatg
     9661 ccttttgata aagaatttta caaaaataaa aaatatttgt tgaaagggaa aagtggtagt
     9721 gggaaaacaa caattttaaa atcgatttta cgagagtatg atgattatag tggaattgta
     9781 aaaattaatg gggtagatgt tagggatata aaagagagtg ttctttttga caatatagct
     9841 tatgtttccc aaaaacctca cttgttcagc gcaagtctta gagacaacct gacattattt
     9901 tctgaagact tcactgataa tgagatagtt gaggttttaa aatttgttga attatctaaa
     9961 tgggctaata aagattgctt ggatatgatg ctttcaaatg atgatataaa attatcagga
    10021 ggggaggtca aaagggtttc tttagctcga gccttattga tgaataagaa tattctgtta
    10081 ttggatgagt tctctgctgg gattgattat gaaacattgt taaaaataga gaagaaactc
    10141 attgatttgg ataagatgat tatttacgtg acgcatgtgg atatagatag atccggcaaa
    10201 cagtttgatg atgtcattga tttggattgt ctttttatat cctcgtgaca tgagagttga
    10261 gtcagttgaa ttattttgtc actctgttta gttcttgttg gtagtgtcag gtaatctttg
    10321 ttaatttttc aggaagtcta ttgaaatatc ctcttggtta tatattacga ggagtaatta
    10381 atggatattc tcgagaattc aatacaacaa tttgattcta aagttaagta tgtttcttta
    10441 tttgcggaat caatctttta tcagatacca tgagctattt tgcaggtgct atgatttctc
    10501 ctttgtatgt gaggattatc ggagatgata tgacagatgc tatgggggtt agacaggcaa
    10561 ctgctggtgt agttaatatt ctcagcaacc ttataggggg agttttgatt gggggtcatc
    10621 agtcttcaga tgtttgtagg tttgaatgct ttgacctttc tttttgcact gttgggtgtg
    10681 gtgtttattc gtacttcttt gagagatatt gaggaacaga tggaggttag taaaagatta
    10741 gccgcaaaat cttttggaga gcatttcctc cattcaatga agatattgtc aagttttcca
    10801 gccatcatca aattaatatt cattgcagct atgaaccaag tgattttaag cattattatc
    10861 cctttaacga ctttgatgtt aatccatcat ccatttatct tctttgacac tgggaaatcc
    10921 attgcagcat tgtcagtggt tattttttca ggaacgattg tgggaagttt tttgagtgga
    10981 ggtatcctaa aaaatattcc cataaaaatg attgtctact ttgaagaaat tatgcatctc
    11041 tgtattctct tttcttggtt gaccaatcat ttcctccttt tattggtagt tgtcttctta
    11101 tgcgcagttg cagtaggaat gatggggcct cggattttca accttgtatt ctcgatggtt
    11161 ccagaagaag tcatgggaac catccagtca gtgcttggag tattcaatgt tgttgtacca
    11221 ggaattctta gcatgctcat cgttgcctta gcgagtgcta caaacctaaa aatcacagtg
    11281 cttccacttt ttatttttgt attgactgcc ttagcaattg tgaaagcaat gaaaatagag
    11341 taatagtagt atgaactact gtctcttttt gggtgggagt tcattaccca tcagacgtcc
    11401 ttgccagtct ctgtgtgggc ttgggagttt tgtttatcga gtttcccttc tatgacaagc
    11461 tccgcttcca atggcgattt aaaggcaaac agaagtgagt atcgaattcc cttgaggaga
    11521 aagaaatgaa agtcaatata gcagatcttc atccgactca actatattta tcagaaaaga
    11581 agttgcaaga tattcagatg ctttaccagt cggcagaaac aatccaagtc gatccaatca
    11641 gtattcttgc ctttggagat tgtttgctga ttacagatgg gcatcacagg gcttatcagg
    11701 ctttattggc aggtcgggat acgatttctg ctgagtggga tagagatggt ggtgatgaac
    11761 tatatcatct ctatgcgcaa gcttgcgagg aaagaaagat ttactctgtt tttgatttaa
    11821 aaaatcatat cttacctctt tggatcggca tggtgagctt tttttgattg aagtcaagga
    11881 gaagggagaa tggtttccaa ttggggatat tacactatct caggataatc tccccattgt
    11941 gattgggaat tccgcttacc aacatcgagg acttggaaaa aagattctaa gtgctttgat
    12001 tgaattggct cgagtaaaag gatggaaaga attgagagtc aaggaaatct acacctacaa
    12061 tcatgcttct aggaggtgtt tcaagtcgct tggatttgtg gaaaatggag caacagaaaa
    12121 aggaaggagt tttatattgg aattagtcta atcctgccac tttctccccc ttaacctttg
    12181 actattccgc aaaattatcg taaaataaag agtaaatgat aaaatgaggt cagagtctgt
    12241 tcgctctgac gatagtagta taaatgagga gaaacgcttt ggaattagaa gtatttgctg
    12301 ggcaagaaaa aagtgaacta tctatgattg aggtagcgcg tgctatatta gaacttcgtg
    12361 gtcgcgatca tgagatgcat tttagcgatc ttgtaaacga aattcaaaac taccttggaa
    12421 catcaaacag cgatatccgc gaagctttgc ctctgttcta cacagagttg aactttgacg
    12481 gtagcttcat ctcacttggg gacaacaaat ggggtcttcg ttcatggtat ggtgtggacg
    12541 aaatcgacga agaaatcatc gctcttgaag aaaatgacga cgatgaagta gcaccaaaag
    12601 ctaagaaaaa acgtgtcaat gcctttatgg atggtgattc agatgccatt gactacaatg
    12661 cagatgatcc agaagacgaa gatgcatacg aagcagatcc agctctttca tacgatgatg
    12721 aaaatccaga tgatgaaaaa aatgaagtgg aagcttatga tgcagaaatc aacgaaatcg
    12781 ctccagatga cttgggagaa gatgtggatc tcaacgaaga cgacgacgag ttttcagatg
    12841 acgacgctga aaccagcgag gaataagagt tagctattga caattatcct atttttaggt
    12901 atcatattgt ttgggcacct cttttagagg tcggggctcc ctagttctta gggagctatt
    12961 tttgtttttt caagaagtta tcttcttgta ttttatactc aatgaaaatc aaagagcaag
    13021 ctaggaaact ggccgtaggc tgctcaaaac actgttttga ggttgtagat aagactgaca
    13081 aagtcaggaa cacatatcta cggcaaggcg acgttgacgc ggtttgaaga gattttcgaa
    13141 gagtattagt tgtgaatctg gtgcagtcgt cccagattat tcttattagt agggtcttgt
    13201 tttctatatc ccctcgtagt taacaagacc ttgagcattt tagaaagagg aatctatgtc
    13261 tacgaaatat atttttgtaa ctggtggtgt ggtatcgtct attgggaaag ggattgtggc
    13321 agcgagtcta ggccgtctct tgaaaaatcg tggtctcaaa gtaaccattc aaaagtttga
    13381 cccttatatc aatattgatc cgggaaccat gagtccttac cagcacgggg aagtttttgt
    13441 gacagatgac ggagctgaga cagatttgga cttgggtcac tatgaacgtt tcatcgatat
    13501 caatctcaac aaatattcca acgtgacaac tgggaaaatt tacagtgaag ttcttcgtaa
    13561 agaacgccgt ggagaatacc ttggggcaac tgttcaagtc attcctcata tcacagatgc
    13621 tttgaaagaa aaaatcaagc gtgccgctct aacgaccgac tctgatgtca ttatcacaga
    13681 ggttggtgga acagtaggag atatcgagtc cttgccattc ctagaggctc ttcgtcagat
    13741 gaaggcagat gtgggtgcgg ataatgtcat gtatatccat acaaccttgc ttccttacct
    13801 caaggctgct ggtgaaatga aaaccaaacc aacccaacac tctgtcaaag aattgcgtgg
    13861 cttgggaatc caaccaaata tgttggttat tcgtacagaa gagccagctg gtcaaggaat
    13921 taaaaataaa ctggcccagt tctgtgatgt ggcaccagaa gccgttatcg aatcgttgga
    13981 tgttgaacac ctttaccaaa ttccactgaa cttgcaggca caagggatgg accaaattgt
    14041 ttgtgatcat ttgaaattag acgcaccagc agcggatatg acagaatggt cagccatggt
    14101 ggacaaggtc atgaacctca agaaacaagt taagatttcc cttgttggta agtatgtgga
    14161 gttgcaagat gcctatatct cagtggtcga agccttgaaa cactctggct atgtcaatga
    14221 tgtagaagtt aaaatcaatt gggtcaatgc caatgatgtg acagcagaga atgtagcaga
    14281 actcttgtct gatgcggacg ggatcatcgt accaggtggt tttggtcaac gtggtacaga
    14341 agggaaaatc caagccatcc gctatgcgcg tgaaaatgat gttccaatgt tgggagtctg
    14401 cttgggaatg cagttgacat gtatcgagtt tgctcgtcac gttttaggtc ttgaaggtgc
    14461 caattctgca gagcttgcac cagaaacaaa ataccctatc attgatatca tgcgtgatca
    14521 gattgatatt gaggatatgg gtggaaccct tcgtttggga ctttatccgt ctaagttgaa
    14581 acgtggctct aaggctgctg ctgcttatca caatcaagaa gtggtgcaac gccgtcaccg
    14641 tcaccgttat gagtttaata atgccttccg tgagcagttt gaggcagcag gttttgtctt
    14701 ttcaggagtt tctccagaca atcgtttggt agaaatcgtg gaaattcctg aaaataaatt
    14761 ctttgtagct tgtcagtatc accctgaact gtcaagccgt ccaaaccgac cagaagaact
    14821 ctacactgcc tttgttactg cagcggttga gaacagcaat tagcaaaatc agaacctttg
    14881 agaaaaatct cagaggtttt ttgcatacga tgatattgca atatatctga ggtagggggc
    14941 ctctgtatgt acctgctacc gttgaaatca atagcgactc cctcttgccc tgtgctagtg
    15001 aatggattta tcagtatatt gaaatgaaat aaaatttgaa caaattaatt cggaaagcca
    15061 aatcaatttc tagcaaagtt ttaggaactg gattgtatag tgaattgaaa taagatgtga
    15121 acatctctat cagaaaagtc aaattaattt atagaaatat tttagcagtc aagatgtact
    15181 gttatagatt caatacatta tactttttta atttaatcca ctatagtaaa atgaaataag
    15241 aacaggacaa atcgatcagg acagtcaaat cgatttctaa caatgtttta gaaatagagg
    15301 tgtactattc tagtttcaat atactatata tctgcagaat actctttcag tttcattcag
    15361 cctagtcttg cttaggaaaa agtaaaaagc catccaatta tgatggatag cttcttggtt
    15421 cttagatttg ttctgcaaaa accttttcag caaggttcat agcgtggtct gatacacgag
    15481 tgtagtgtga gatgatgtcg ataaagttga ccccagcttg tgttgaacat tcgcctttgt
    15541 tgaggcgttt gatgtgggtt tttctgagaa cacgttctat cttattgatt gcttcatgac
    15601 gttctacaag actgcgtgct ttttcaatat cattgttttc cacactatcc agagcatctt
    15661 tgataaagtc actagtttgg cggtaaactt cctctaattc tttcaaggcg gcatcagaaa
    15721 attcaacatt tttccgttga agatagtcag tcagattgag tagagcctcc gtgtggtctc
    15781 caatccgttc caaatcacgg gaggaatcaa ggatattggt aagcacttca ctttcttttt
    15841 ggctgagagc ttcgcttgaa agggcaatga gataacgtgt taattgctca tcgatggtgt
    15901 taattgcttc ttcggtttta tgcccttttt cagcaacttt ttcatccaag tcaatgatgt
    15961 acttatagga aaggtcaaag gctttagcag cgtagtttcc taagtgcaag agctctttct
    16021 tagcatttcc tagagcgata gatggggcct gtttgatgaa atgttcatca agatataagg
    16081 gttcgtattt gacaacctcg tcctctccag gaataatctt ggttacaaag taagccagag
    16141 ctccgataaa tggaaattgg acaatggtgt tggtaatatt aaaggttccg tgagcaaagg
    16201 cgatggtcat ttccggtgct agatttagcg tagcttcaaa ccaatgaatc aggacagtaa
    16261 aaggaactag aaaaataacg cagacgactg ttccgataac gttgaaggca acatgagctc
    16321 ctgctacccg tttagctgca atattagccc ctaaagaggc aatgatggct gtaatggtta
    16381 tcccgatatt gtcaccaaat agaactggca aagctccctg taggtcaatt agattgccgg
    16441 cgtagaggtt ttgtaaaatc ccaatggtag ccgaagaagc ttgaattagc aaggtcaagc
    16501 cggtaccgac aaagacaccc aaaacaggat tcttacttag ctcaatcata tagtccttaa
    16561 agacctgtaa atccttgagt ggagccattg cgccgctcat gagattgagg gcaaaaaaga
    16621 taccaccgac accaaagagg atgcgtccga tattattgac tgtccgattt tttgtaaaaa
    16681 agagacagac ggcaccgata aagagcatag gtagggcata gttacctaat ttaaaaccga
    16741 tgagaaagga tgtgacagtt gtcccaatat tagcacccat gacaatcccg atagcctgac
    16801 gtaaggttaa gagaccggca ctgaccaggc cgactgtgat aactgttaca ccagaactag
    16861 actgaattag agcagtcatc ccaataccaa ccagaactcc aaagaaagga ttactagtat
    16921 atttgtcaat gtaaaaacga aggcgatctc cagcagcttg ttgcaaaccg tctcccatgg
    16981 tcttgatgct atataagaat agccccagac cacctaaaaa gtgaaataaa atttcctgcc
    17041 aattaatgga catttctttt tcctccgaaa aataatcgcg gaatatcttc tattctattt
    17101 taaaggataa aagtaaatct aacaagtgtt aatgtcaagt ttgtaaaaga aaattataat
    17161 tgataagtgt attattttta agagttttta accttatttt agatttgtgc aaacagttat
    17221 tgttttttgt ctaaaaatgt tttaggataa aaatgtgatt atcatggttc tagagtttga
    17281 taaaaaacta cagaatataa agcgctttct tgaaaacaac aaaatcaatc ttttaggagg
    17341 agaaaatgaa gaatccattt tttgaaagac gttgtcgtta cagtattcgt aagttatcag
    17401 taggagcctg ctcgctgatg attggtgctg ttttatttgc tggtccagcc ttggctgaag
    17461 aaactgcagt tcctgaaaat agcggagcta atacagagct tgtttcagga gagagtgagc
    17521 attcgaccaa tgaagctgat aagcagaatg aaggggaaca tgctagagaa aacaagctag
    17581 aaaaggcaga aggagtagcg atagcatctg aaactgcttc gccagcaagc aatgaagctg
    17641 caactactga aactgcagaa gcagctagcg cagctaaacc agaggaaaaa gcaagtgagg
    17701 tggttgcaga aacaccatct gcagaagcaa aacctaagtc tgacaaggaa acagaagcaa
    17761 agcccgaagc aactaaccaa ggggatgagt ctaaaccagc agcagaagct aataagactg
    17821 aaaaagaagt ccagccagat gtccctaaaa atacagaaaa aacattaaaa ccaaaggaaa
    17881 tcaaatttaa ttcatgggaa gaattgttaa aatgggaacc aggtgctcgt gaagatgatg
    17941 ctattaaccg cggatctgtt gtcctcgctt cacgtcggac aggtcattta gtcaatgaaa
    18001 aagctagcaa ggaagcaaaa gttcaagcct tatcaaacac caattctaaa gcaaaagacc
    18061 atgcttctgt tggtggagaa gagttcaagg cctatgcttt tgactattgg caatatctag
    18121 attcaatggt cttctgggaa ggtctcgtac caactcctga cgttattgat gcaggtcacc
    18181 gtaacggggt tcctgtatac ggtacactct tcttcaactg gtctaatagt attgcagatc
    18241 aagaaagatt tgctgaagct ttgaagcaag acgcagatgg tagcttccca attgcccgta
    18301 aattggtaga catggccaag tattatggct atgatggcta tttcatcaac caagaaacaa
    18361 ctggagattt ggttaaacct cttggagaaa agatgcgcca gtttatgctc tatagcaagg
    18421 aatatgctgc taaggtaaac catccaatca agtattcttg gtacgatgcc atgacctata
    18481 actatggacg ttaccatcaa gatggtttgg gagaatacaa ctaccaattc atgcaaccag
    18541 aaggagataa ggttccggca gataacttct ttgctaactt taactgggat aaggctaaaa
    18601 atgattacac tattgcaact gccaactgga ttggtcgtaa tccttatgat gtatttgcag
    18661 gtttggaatt gcaacagggt ggttcctaca agacaaaggt taagtggaat gacattttag
    18721 acgaaaatgg gaaattgcgc ctttctcttg gtttatttgc cccagatacc attacaagtt
    18781 taggaaaaac tggtgaagat tatcataaaa atgaagatat cttctttaca ggttatcaag
    18841 gagaccctac tggccaaaaa ccaggtgaca aagattggta tggtattgct aacctagttg
    18901 cggaccgtac gccagcggta ggtaatactt ttactacttc ttttaataca ggtcatggta
    18961 aaaaatggtt cgtagatggt aaggtttcta aggattctga gtggaattat cgttcagtat
    19021 caggtgttct tccaacatgg cgctggtggc agacttcaac aggggaaaaa cttcgtgcag
    19081 aatatgattt tacagatgcc tataatggcg gaaattccct taaattctct ggtgatgtag
    19141 ccggtaagac agatcaggat gtgagacttt attctactaa gttagaagta actgagaaga
    19201 ccaaacttcg tgttgcccac aagggaggaa aaggttctaa agtttatatg gcattctcta
    19261 caactccaga ctacaaattc gatgatgcag atgcatggaa agagctaacc ctttctgaca
    19321 actggacaaa tgaagaattt gatctcagct cactagcagg taaaaccatc tatgcagtca
    19381 aactattttt cgagcatgaa ggtgctgtaa aagattatca gttcaacctc ggacaattaa
    19441 ctatctcgga caatcaccaa gagccacaat cgccgacaag cttttctgta gtgaaacaat
    19501 ctcttaaaaa tgcccaagaa gcggaagcag ttgtgcaatt taaaggcaac aaggatgcag
    19561 atttctatga agtttatgaa aaagatggag acagctggaa attactaact ggctcatctt
    19621 ctacaactat ttatctacca aaagttagcc gctcagcaag tgctcagggt acaactcaag
    19681 aactgaaggt tgtagcagtc ggtaaaaatg gagttcgttc agaagctgca accacaacct
    19741 ttgattgggg tatgactgta aaagatacca gcctaccaaa accactagct gaaaatatcg
    19801 ttccaggtgc aacagttatt gatagtactt tccctaagac tgaaggtgga gaaggtattg
    19861 aaggtatgtt gaacggtacc attactagct tgtcagataa atggtcttca gctcagttga
    19921 gtggtagtgt ggatattcgt ttgaccaagc cacgtaccgt tgttagatgg gtcatggatc
    19981 atgcaggagc tggtggtgag tctgttaacg atggcttgat gaacactaaa gactttgacc
    20041 tttattataa agatgcagat ggtgagtgga agctagctaa ggaagtccgt ggtaacaaag
    20101 cacacgtgac agatatcact cttgataaac caatcactgc tcaagactgg cgcttgaatg
    20161 ttgtcacttc tgacaatgga actccatgga aggctattcg tatctataac tggaaaatgt
    20221 atgaaaagct tgatactgag agtgtcaata ttccgatggc caaggctgca gcccgttctc
    20281 taggcaataa caaggtacaa gttggctttg cagatgtacc ggctggagca actattaccg
    20341 tttatgataa tccaaattct caaactccgc tcgcaacctt gaagagcgaa gttggaggag
    20401 acctagcaag tgcaccattg gatttgacaa atcaatctgg tcttctttat tatcgtaccc
    20461 agttgccagg caaggaaatt agtaatgtcc tagcagtttc cgttccaaaa gatgacagaa
    20521 gaatcaagtc agtcagccta gaaacaggac ctaagaaaac aagctacgcc gaaggggagg
    20581 atttggacct tagaggtggt gttcttcgag ttcagtatga aggaggaact gaggacgaac
    20641 tcattcgcct aactcacgca ggtgtatcag tatcaggttt tgatacgcat cataagggag
    20701 aacagaatct tactctccaa tatttgggac aaccagtaaa tgctaatttg tcagtgactg
    20761 tcactggcca agatgaagca agtccgaaaa ctattttggg aattgaagta agtcaggaac
    20821 cgaaaaaaga ttacctagtt ggtgatagct tagacttgtc tgaaggacgc tttgcagtgg
    20881 cttatagcaa tgacaccatg gaagaacatt cctttactga tgagggagtt gaaatttctg
    20941 gttacgatgc tcaaaagact ggtcgtcaaa ccttgacgct tcgttaccaa ggtcatgaag
    21001 tcaactttga tgttttggta tctccaaaag cagcattgaa cgatgagtac ctcaaacaaa
    21061 aattagcaga ggttgaagct gctaagaaca aggtggtcta taactttgct tcaccagaag
    21121 taaaagaagc tttcttgaaa gcaattgaag cggccgaaca agtgttgaaa gaccatgaaa
    21181 ctagcaccca agatcaagtc aatgaccgac ttaataaatt gacagaagct cataaagctc
    21241 tgaatggtca agagaaattt aaggaagaaa agacagagct tgatcgttta acaggtgagg
    21301 ttcaagaact cttggctgcc aaaccaaacc atccttcagg ttctgcccta gctccgcttc
    21361 ttgagaaaaa caaggccttg gttgaaaaag tagatttgag tccagaagag cttgcaacag
    21421 cgaaacagag tctaaaagat ctggttgctt tattgaaaga agacaagcca gcagtctttt
    21481 ctgatagtaa aacaggtgtt gaagtacact tctcaaataa agagaagact gtcatcaagg
    21541 gtttgaaagt agagcgtgtt caagcaagtg ctgaagagaa gaaatacttt gctggagaag
    21601 atgctcatgt ctttgaaata gaaggtttgg atgaaaaagg tcaagatgtt gatctctctt
    21661 acgcttctat tgtgaaaatc ccaattgaaa aagataagaa agttaagaaa gtatttttct
    21721 tacctgaagg caaagaggca gtagaattgg cttttgaaca aacggatagt catgttatct
    21781 ttacagcacc acactttact cattatgcct ttgtttatga atctgctgaa aaaccacaac
    21841 ctgctaaacc agcaccacaa aacaaagtcc ttccaaaacc tacttatcaa ccggcttctg
    21901 atcaacaaaa ggctcctaaa ttggaagttc aagaggaaaa ggttgccttt catcgtcaag
    21961 agcatgaaaa tgctgagatg ctagttgggg aacaacgagt catcatacag ggacgagatg
    22021 gactgttaag acatgtcttt gaagttgatg aaaacggtca gcgtcgtctt cgttcaacag
    22081 aagtcatcca agaagcgatt ccagaaattg ttgaaattgg aacaaaagta aaaacagtac
    22141 cagcagtagt agctacacag gaaaaaccag ctcaaaatac agcagttaaa tcagaagaag
    22201 caagcaaaca attgccaaat acaggaacag ctgatgctaa tgaagcccta atagcagtct
    22261 tagccagcct tggtcttgct agtttagcct tgaccttgag acggaaaaga gaagataaag
    22321 attaaatatc gaaaaatctt gtgaaatctt tccttatatt tccaaagtgt gatataatag
    22381 tttcgaataa aataaataaa ggagtttttg taacatggca aaacttactg ttaaagacgt
    22441 tgacttgaaa ggtaaaaaag tcctcgttcg tgttgacttc aacgtaccat tgaaagatgg
    22501 cgtaatcact aacgataacc gtatcacagc agctcttcca actattaagt acatcatcga
    22561 acaaggtgga cgtgcaattc ttttctctca ccttggacgt gtgaaagaag aagctgataa
    22621 agctggcaaa tcacttgctc ctgtagcagc tgacttggca gcaaaacttg gtcaagatgt
    22681 tgttttccca ggtgtcactc gtggtgctga attggaagcg gcaatcaacg ctcttgaaga
    22741 tggacaagtt ctcttggttg aaaacactcg ttacgaagat gttgacggca agaaagaatc
    22801 taaaaacgat cctgaacttg gtaaatactg ggcatcactt ggagatggta tcttcgtaaa
    22861 cgatgcattc ggtacagctc accgtgcaca cgcatctaac gttggtatct cagcaaacgt
    22921 tgaaaaagca gttgctggtt tccttcttga aaacgaaatt gcctacatcc aagaagcagt
    22981 tgaaactcca gaacgtccat tcgtggctat ccttggtggt tcaaaagttt cagacaagat
    23041 cggtgttatc gaaaacttgc ttgaaaaagc tgataaagtc cttatcggtg gtgggatgac
    23101 ttacacattc tacaaagcac aaggtatcga aatcggtaac tcacttgtag aagaagacaa
    23161 attggatgtt gcgaaagctc ttcttgaaaa agcaaatggt aaattgatct tgccagttga
    23221 ctcaaaagaa gctaacgcat ttgctggtta cactgaagtg cgtgacactg aaggtgaagc
    23281 agtttctgaa ggcttccttg gtcttgacat cggtccaaaa tctatcgcca aatttgacga
    23341 agctttgact ggtgccaaaa cagttgtatg gaacggacct atgggtgtat ttgaaaaccc
    23401 agatttccaa gctggtacaa tcggtgtgat ggacgctatc gtgaaacaac caggagttaa
    23461 atcaatcatc ggtggtggtg actcagctgc cgcagcgatt aaccttggcc gtgcagacaa
    23521 gttctcatgg attagtacgg gtggtggagc atcaatggaa cttcttgaag gtaaggttct
    23581 tccaggactt gcagccttga cagaaaaata agattttata aacaaatcaa agaagagagg
    23641 gatgaaagtt cctcttttct tttgcttaaa ataaaaacgc ttcctctcaa ctattactca
    23701 taaaaatcac cgatttatga taaaatggaa atagaaagtt gagattatga gttattttaa
    23761 aaaatataaa ttcgataaat cccagttcaa acttggtatg cgaaccttta aaacaggtat
    23821 tgctgttttt ctagttctct tgatttttgg cttttttggc tggaaaggtc ttcaaattgg
    23881 tgctttgaca gccgttttta gcctgaggga gagttttgat gagagtgttc attttgggac
    23941 ttcgcgtatt ctaggaaata gtatcggtgg actctatgcc ttggtcttct tcttattaaa
    24001 tacttttttc cacgaagcct tttgggtgac cttggtagtt gttccaatct gcaccatgtt
    24061 aaccattatg acaaatgtag ccatgaataa caaagcaggg gttattggtg gtgtagcagc
    24121 tatgttaatc attaccctat caattccaag tggtgagaca attttgtacg tgtttgtgcg
    24181 tgtattagaa acgtttatgg gagtttttgt cgcaattatc gtaaattacg atattgatcg
    24241 tattcgtctc tttttagaga aaaaagaaaa ataatgttac attttataac attatcaatt
    24301 gacgtttgtc tttttttaga ctataataga cagaaagaag gaaattgtaa atgaaggaaa
    24361 aagaatttcg ccgaaatatg gctgtttttc ctatcggcag tgttatgaag ttgaccgatt
    24421 tatcggcgcg tcagattcgt tattatgaag atcaagagtt gatcaagccc gatcgaaacg
    24481 aaggaaatcg tcgcatgtat tccttgaatg acatggatcg tctgcttgaa atcaaagatt
    24541 atatctctga aggttataat atcgctgcca ttaagaaaaa atatgctgaa cgtgaagcga
    24601 aatccaagaa agcggttagt cagactgaag tacgtcgtgc acttcacaat gaactcctcc
    24661 aacaggggcg ttttgcttca gtacagtcac cttttggtcg cggttaggca accgcaagta
    24721 gtcatagatt aaggagaaaa cttatgccaa tcacagctgc agatattcgt cgtgaagtca
    24781 aggaaaaaaa tgttaccttt attcgtctta tgttctcaga tattttggga accatgaaaa
    24841 acgtcgaaat tcctgctaca gatgaacagt tagataaggt cttgtcgaac aaggttatgt
    24901 ttgatggatc ttctattgaa ggttttgtac gtatcaatga gtcggatatg tacttgtacc
    24961 cggacttgga tacatggaca gtcttccctt ggggagatga aaatggaagt gttgcaggtc
    25021 tgatctgtga tgtctataca acagaaggtg aaccatttgc gggtgaccct cgtggtaatt
    25081 tgaaacgagc tcttcgtcac atggaagaag ttggattcaa atccttcaac cttggtccag
    25141 agccagaatt cttcctattt aagttggatg aaaatgggga cccaacactt gaagtgaatg
    25201 acaagggtgg ctactttgat ttggcaccta ctgaccttgc ggacaacaca cgtcgtgaga
    25261 ttgtgaatgt cttgaccaaa atgggatttg aagtagaagc gagtcaccac gaggttgcgg
    25321 ttggacagca tgagattgac tttaagtacg atgaagttct ccgtgcttgt gataagattc
    25381 aaatctttaa gcttgttgtt aaaaccattg ctcgcaaaca cggactttac gcaacattta
    25441 tggcgaagcc aaaatttggt attgctggat caggtatgca ctgtaatatg tccttgtttg
    25501 atgcagaagg aaataacgcc ttctttgatc caaatgatcc aaaaggaatg cagttgtcag
    25561 aaacagctta ccatttccta ggcggtttga tcaagcatgc ttacaactat actgccatca
    25621 tgaacccaac agttaactca tacaaacgtt tggttccagg ttatgaagcg cctgtttaca
    25681 ttgcttgggc tggtcgtaac cgttcgccac ttgtgcgcgt acctgcttca cgtggtatgg
    25741 gaactcgtct tgagttgcgt tcagtggatc caatggcgaa cccttacatt gctatggctg
    25801 ttcttttgga agttggtttg tatggtattg aaaataaaat cgaagcacca gctcctatcg
    25861 aagaaaatat ctacatcatg acagcagaag agcgcaagga agctggtatt acagaccttc
    25921 catcaactct tcacaacgct ttgaaagctt tgacagaaga tgaagtggtt aaagctgctc
    25981 tcggagatca catctacact agcttccttg aagccaaacg aatcgaatgg gcaagttatg
    26041 caaccttcgt ttcacaatgg gaaattgata attatttaga cctttactaa tactaatata
    26101 gaagaaagat tgcctgtggg taaacagtca cacagcagtc taagccatca aatacctata
    26161 acccttaaaa tagcgatttc ggtcgctatt tatttttcga aaaatcctct tgactctttt
    26221 gcgaattaga tttatcatca gacgtgtaga agaaaatcaa ggagtcacta tggaaaaatt
    26281 caatttcaaa aacaatatcg ggcaagaaaa caagttactt caaatcgaaa tctacaagtt
    26341 tactaacttt tgcaagcttc aaaattacac atctgtaaat attttttcga aagatatatt
    26401 tgaagccata gtaaattgag actagaatag tacactacat ctgctaaaaa tttctagaaa
    26461 ttaatttaac tttcctaatc gatttgttta catcttattt caatctacta tattatctca
    26521 ataaatgatg atggcgactg ttttgtttgt gcttgtcgat ttttgaatcc tgatcgagcg
    26581 gaagaatatt tctgccgagg ttgtcaaggg gaaaatcctg aagatattga attttatgat
    26641 gaacaattac aggcagaaaa ggtggaggct ttgaatattc gattggaagt aaaaaattga
    26701 attatctaca atctcatcaa caataaacct atttcaaccc cattatctat aggcgtattt
    26761 ttacgccttt ttatatactt gaagcacata agaaacatta tgggaagttt gctgatggaa
    26821 gtactcaaga aattgatgtt ccttatgata ttcctgatac ttgggagtgg gtgaggataa
    26881 aatcaattta ttggaatttt gggcaaaata agccagagaa atcctttagg tatatagata
    26941 cgtctagtat tgatagaaaa aagaacataa tcaactacaa aaatctacaa tatctttcac
    27001 ctgaacaagc gccttcccgt gccagaaaat tagtttcgca gaatagtgtc ttattttcaa
    27061 cagttagacc atatctaaaa aatattgctg tagttagaga acttaaagag tatttgatag
    27121 ctagtacagc atttattgtt ttggatactt tacttaacga aacatatttg aaatattatt
    27181 tattatcaga taattttatc aatcgtgtta ataataaatc tactggaaca agttatcctg
    27241 caatcaatga ttataatttt aatctattat taatt
//
LOCUS       DAVAZT010000028        26633 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVAZT010000028 DAVAZT010000000
VERSION     DAVAZT010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26633
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.028"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            58..273
                     /locus_tag="VQT45_001120"
     CDS             58..273
                     /locus_tag="VQT45_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359449.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNHEKFED"
     gene            complement(472..1236)
                     /locus_tag="VQT45_001121"
     CDS             complement(472..1236)
                     /locus_tag="VQT45_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2359450.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEEIAKENLEKVGMGERYWQARPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLILNENQRAN"
     gene            complement(1236..2801)
                     /locus_tag="VQT45_001122"
     CDS             complement(1236..2801)
                     /locus_tag="VQT45_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET2359451.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKKPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMCKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            2939..4828
                     /locus_tag="VQT45_001123"
     CDS             2939..4828
                     /locus_tag="VQT45_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HET2359452.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMG
                     ALTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDQAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSLFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            complement(5129..6148)
                     /locus_tag="VQT45_001124"
     CDS             complement(5129..6148)
                     /locus_tag="VQT45_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HET2359453.1"
                     /translation="MLYVGIDIAKNKHDVTALNVPGKTVLKPLTFSNNKAGFELLDLS
                     LRQLNQDCLIALENTGHYAFNLLNFLHEQGYKVYTYTPLLIKEFAKSLSLRKTKTNKK
                     DAHGIALKLLSDPNREQFQHDNRQVELKILARHIHRLKKKQSDWKVQYTRCLDIIFPE
                     LDKIVEKHSEYTYQLLTCYPNPQKRLEAGFDKLIEIKRLTASKIQDILSVAPRSIGTT
                     SPAREFEIIKHYKRLIDKAETCVNDLMAEFNSVITTVTGIGNRLEAVILAEIRNIHAF
                     DNPAQLQAFAGLDSSIYQSGQIDLAGRMIKRGSPHLRWALIQAAKACPRFSPAFKAYL
                     KTKLE"
     gene            6403..7248
                     /locus_tag="VQT45_001125"
     CDS             6403..7248
                     /locus_tag="VQT45_001125"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HET2359454.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            complement(7395..8456)
                     /gene="dinB"
                     /locus_tag="VQT45_001126"
     CDS             complement(7395..8456)
                     /gene="dinB"
                     /locus_tag="VQT45_001126"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HET2359455.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSKKERGVRLLGITMTGF"
     gene            8804..11128
                     /gene="pflB"
                     /locus_tag="VQT45_001127"
     CDS             8804..11128
                     /gene="pflB"
                     /locus_tag="VQT45_001127"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HET2359456.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            complement(11495..11713)
                     /locus_tag="VQT45_001128"
     CDS             complement(11495..11713)
                     /locus_tag="VQT45_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359457.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(11809..12047)
                     /locus_tag="VQT45_001129"
                     /pseudo
     CDS             complement(11809..12047)
                     /locus_tag="VQT45_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(12040..12324)
                     /locus_tag="VQT45_001130"
     CDS             complement(12040..12324)
                     /locus_tag="VQT45_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359458.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            complement(12936..13106)
                     /locus_tag="VQT45_001131"
     CDS             complement(12936..13106)
                     /locus_tag="VQT45_001131"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2359459.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEETG"
     gene            complement(13756..14979)
                     /locus_tag="VQT45_001132"
     CDS             complement(13756..14979)
                     /locus_tag="VQT45_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET2359460.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            15147..16469
                     /locus_tag="VQT45_001133"
     CDS             15147..16469
                     /locus_tag="VQT45_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2359461.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            16471..18357
                     /locus_tag="VQT45_001134"
     CDS             16471..18357
                     /locus_tag="VQT45_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HET2359462.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYINRVFKTDIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFVP
                     ELRFEDFLDKELSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            18525..18869
                     /locus_tag="VQT45_001135"
     CDS             18525..18869
                     /locus_tag="VQT45_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2359463.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            18879..20291
                     /gene="lacG"
                     /locus_tag="VQT45_001136"
     CDS             18879..20291
                     /gene="lacG"
                     /locus_tag="VQT45_001136"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET2359464.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDITLAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGEIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAALNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            20361..22040
                     /locus_tag="VQT45_001137"
     CDS             20361..22040
                     /locus_tag="VQT45_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET2359465.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMIAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGIIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QLISFVFLSLMLVVDILIYLPFCRAYDRQLLVKEDIASSNDIILEEDTSEIMPGEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLDIQIVATRGMEYIHLTKSPSKALQFVLEHYQAV"
     gene            complement(22166..23605)
                     /locus_tag="VQT45_001138"
     CDS             complement(22166..23605)
                     /locus_tag="VQT45_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET2359466.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(23609..24958)
                     /gene="trkA"
                     /locus_tag="VQT45_001139"
     CDS             complement(23609..24958)
                     /gene="trkA"
                     /locus_tag="VQT45_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HET2359467.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            25146..25994
                     /locus_tag="VQT45_001140"
     CDS             25146..25994
                     /locus_tag="VQT45_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HET2359468.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            26009..26557
                     /locus_tag="VQT45_001141"
     CDS             26009..26557
                     /locus_tag="VQT45_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HET2359469.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
BASE COUNT         7954 a         4597 c         5575 g         8507 t
ORIGIN      
        1 aaaagtagta aaaacgtata caattaaata ttataaagaa gaaaatagga gaaaaacatg
       61 gctaagtcaa actttgaaaa agtagaatca gttgttggct gggttcgtga taagaaaatc
      121 acaggctacc gtatctctaa agaaacgaat gcgcgtgaaa tgtctatcat tgctctggcg
      181 cagggtcgtg caaaagtaaa aaatatttca tttgaaacag ccctaggctt aattgatttc
      241 tatgaaaaaa atcatgaaaa atttgaagat taatctttgg ataacggtgg attcttgacc
      301 ttcaagtagt agagatagag aatctgcctt ttcattttga ggacagcaaa aagactgcac
      361 ggttgatgca gccttttctt tttatttgat actcttcgaa aatctcttca aaccacgtca
      421 gctctatctg caacctcaaa acagtgtttt gagcaacctg cggctagctg cctagtttgc
      481 tctttgattt tcattgagta tgagataacg ttgaagaaat tcttttgtac ggtcttcttt
      541 aggattagtg aagaggtctt ctggtttacc ttcttcagca atcacaccct tatccataaa
      601 gataacacgg tgagagacat cacgggcaaa ttccatttca tgggttacga caatcatggt
      661 caagccttcc tgagccagat cttgcatgat tttgaggacc tctccaacca tttctggatc
      721 gagagctgat gttggttcat caaagagaat ggcgtcagga ttcattgaaa gggcacgagc
      781 gatggccaca cgttgttttt gaccacctga gagttgtttg ggtctcgctt gccagtagcg
      841 ttctcccatg ccgacctttt ccaggttttc tttggcaatt tcttcagctt ctgtgcgttc
      901 gcgtttaagg acagttgtct gagcgacgat tgtgttttca agaacgttga gattttcaaa
      961 gaggttaaag gattggaaaa ccatccctaa cttttcacgg tattgcgtga ggtcatagcc
     1021 tttttcgagg acgttttgtc catgataaag gatttgtcca tcagttggcg tttcaagtag
     1081 gttaatggag cgtaggaagg ttgatttccc acttccagag cttccgatga tagaaataac
     1141 ttctcccttg tggacagtga gagaaatgtc ttttagcact tcgttttgtc cataggattt
     1201 tttgaggtgt ttaatttcaa ggattgcttg tgtcattatt tcaaatcctc cgtttgcatt
     1261 tggttagcac ctgtagtgta ggtatccatg tccattctgc gctcgataaa gcgtaggata
     1321 cgtgttacgg tgaaggtgag gacaaagtaa atcacggcga tgattgtaaa tgtctggaag
     1381 tattgatagg tttgtgttgc cacggtattt cctgagaaat aaagttcgac aacagagata
     1441 acgttcaata cagatgtatc tttgatattg atgacaaatt cattaccagt tgctggtagg
     1501 atattgcgga caacctgagg taggacaatc ttacacatgg tttggttatg agtcatacca
     1561 agagcagtcg cagcttcaaa ttgtcccttg tcaactgcca ggataccacc acggacaatt
     1621 tcagtcatgt aggcaccggt attgattgaa acgatgaaga tagcagctag tgtacggtca
     1681 aggttgatac cgaaagcttg ggcagttcca tagtagataa ccatcgattg aacaatcatt
     1741 ggcgtaccac ggaaaatttc aatgtagaca ttgagaaccc agccgactag tttttgaagg
     1801 ccataaatgg ctttgttttc agagagagga gcagtacgga agacaccaat ggcaagtcca
     1861 ataatgagac ctatgatggt tccgacgata gagattaaaa gagtgatacc agcaccacgc
     1921 aagagttgtt gccagttttc agaaagaatt ttagcgactt ggctaaagaa actactgcta
     1981 gtctcttcag ttgttgtagc ttcggcaggt tgttccttga tcatacgatc catcaaggca
     2041 acttggtcat cttttgaaat ggtttcaatg ctggcattga tttggctaat acgattgtca
     2101 tttttacgaa gcccgatagc gatagctgta tcttcttccc cagttttgaa accaggttct
     2161 acttgaatca tcttgaactt agagttcgca gcttcagcag tcagtgcttc tggacgttca
     2221 gaaacataag catcaatgac accagcctca agagcttgtc gcatttgagc gaagtctccc
     2281 atggctgttt cttttttagc acctgggatt tgtgcaatca agtcgtagag gtagacccct
     2341 tgttgagaag tgatttttgc accgttaaag tcatccaaag atttagcact tgcgtaggca
     2401 gaatcttttt tgacaagcaa aactggttcg ctagtgtagt aactgctcga aaaggcaatt
     2461 tcttgtttgc gttctgcagt tggactcata cctgcgataa tcatgtcaat cttaccagaa
     2521 gtaagggcag ggactagacc ttcccacttg gttttaacaa ccaaaggttt tttacctaag
     2581 tccttagcga ttttcttggc gatttgaaca tcgtatccgt tggcatactg attggtccca
     2641 tcgattttga cagctccgtt gctatcatca tcctgggtcc agttaaaggg agcatatgct
     2701 gcttccatcc cgatgcgtaa atattcatcg gcttgagcaa cattgacaag tcctagcatc
     2761 agcaagagac ttgtgaaaat agataagtat atttttctca tgatttctcc tattctgatc
     2821 tattaaaaaa taactgtctc ctattttatc gaaaaatgcg taatttttca acataagtaa
     2881 gcctttactt acgaaaaaat gctataatga taagaaagat aaaaaggggg cttagttgat
     2941 gaaaaaaact tttttcttac tggtgttagg cttgttttgc cttcttccac tctctgtttt
     3001 tgccattgat ttcaagataa actcttatca aggggatttg tatattcatg cagataatac
     3061 ggcagagttt agacagaaga tagtttacca gtttgaggag gactttaagg gacaaatcgt
     3121 gggacttgga cgtgctggta agatgcctag cgggtttgac attgaccctc atccaaaggt
     3181 tcaggccgcg aaaaacggtg cagaactagc agatgtgact agcgaagtaa cagaagaagc
     3241 ggatggttat actgtgagag tctataatcc aggtcaggag ggcgacatag ttgaagttga
     3301 cctcgtctgg aacttaaaaa atttactttt cctttatgat gatatcgctg aattaaattg
     3361 gcaacctctg acagatagtt cagagtctat tgaaaagttt gaatttcatg taaggggaga
     3421 caagggagct gaaaaactct ttttccatac agggaaactt tttagagagg gaacgattga
     3481 aaagagtaac cttgattata ctatccgttt agacaatctt ccggctaagc gtggagttga
     3541 gttgcatgcc tattggcctc ggaccgattt tgctagcgct agggatcagg gattgaaagg
     3601 gaatcgttta gaagagttta ataagataga agactcgatt gttagagaaa aagatcagag
     3661 taaacaactt gttacttggg tcctcccttc gatcctttct atctccttgt tattgagtgt
     3721 ctgcttctat tttatttata gaagaaagac cactccttca gtcaaatatg ccaaaaatca
     3781 tcgtctctat gaaccaccaa tggaattaga gcctatggtt ttatcagaag cagtctactc
     3841 gacctccttg gaggaagtga gtcccttggt caagggagct ggaaaattca cctttgatca
     3901 acttattcaa gctaccttgc tagatgtgat agaccgtggg aatgtctcta tcatttcaga
     3961 aggagatgca gttggtttga ggctagtaaa agaagatggt ttgtcaagct ttgagaaaga
     4021 ctgcctaaat ctagcttttt caggtaaaaa agaagaaact ctttccaatt tgtttgcgga
     4081 ttacaaggta tctgatagtc tttatcgtag agccaaagtt tctgatgaaa aacggattca
     4141 agcaagaggg cttcaactca aatcttcttt tgaagaggta ttgaaccaga tgcaagaagg
     4201 agtgagaaaa cgagtttcct tctgggggct cccagattat tatcgtcctt taactggtgg
     4261 ggaaaaggcc ttgcaagtgg gtatgggtgc cttgactatc ctgcccctat ttatcggatt
     4321 tggtttgttc ttgtacagtt tagacgttca tggctatctt tacctccctt tgccaatact
     4381 tggttttcta gggttagttt tgtctgtttt ctattattgg aagcttcgac tagataatcg
     4441 tgatggtgtt ctaaatgaag cgggagctga ggtctactat ctctggacca gttttgaaaa
     4501 tatgttgcgt gagattgcac gattggatca ggctgaactg gaaagtattg tggtctggaa
     4561 tcgcctcttg gtctatgcga ccttatttgg ctatgcggac aaggttagtc atttgatgaa
     4621 ggttcatcag attcaagtgg aaaatccaga tatcaatctc tatgtagctt atggctggca
     4681 cagtctgttt tatcattcaa gcgcgcaaat gagccattat gctagtgtcg caaatacagc
     4741 aagcacctac tctgtatctt ctggaagtgg aagttctggt ggtggcttct ctggaggcgg
     4801 aggtggcggc agtatcggtg ccttttaaag agagctacca tagactgaaa aagtatgata
     4861 taatggaaga tagaaaaaag acaaactata agaaaagtca atagttttat ctaaactatt
     4921 tcttatttca atttgatgat ttggcgatga ttttagagca cggcaaaaag cccttgaaaa
     4981 agtccatttt ttcaaaggta atcctgtgtt aatttcagaa attacatcac tttttgttcg
     5041 tcaaatggca gctctttttt aggatataaa acagggttcg gataagtttt tttgcaaggt
     5101 ggatgatggc tacattgtaa tgttttcctt attctaactt agtcttaaga taggccttaa
     5161 aagcaggtga aaagcgaggg catgctttgg cagcttgtat gagtgcccac cgcagatgag
     5221 gggaaccccg tttgatcatt cttccagcta aatcaatctg acctgactga taaatagaag
     5281 aatccagtcc agcgaaagct tgtaattgag caggattatc aaaggcatga atatttcgaa
     5341 tctcggctaa aatgaccgcc tctaaacgat tcccaatccc agtgaccgtc gtgatgaccg
     5401 agttgaactc agccatcaag tcattgacac atgtttccgc cttgtcaatg agcctcttgt
     5461 aatgtttgat gatttcgaat tcacgagcag gagatgttgt tccgatagaa cgaggtgcaa
     5521 ctgagaggat atcctgaatt ttagaagcgg tcaatcgctt aatttctatc agcttatcaa
     5581 atcctgcctc aagccttttc tgaggattag ggtagcatgt caagagttgg taggtatatt
     5641 ctgaatgctt ttcaacgatt ttatccaact caggaaagat gatatcaaga caacgagtgt
     5701 attgtacttt ccaatcagac tgttttttct tgagacgatg aatatgtcta gccagtattt
     5761 ttagttctac ttgccgatta tcgtgttgaa attgttcacg attggggtca gaaagaagtt
     5821 taagagcgat gccatgagcg tctttcttat tcgttttagt cttgcgaagt gataatgatt
     5881 tggcaaattc cttgatgagc aaaggagtgt aggtgtaaac tttatatcct tgttcatgca
     5941 ggaagttcag tagattaaag gcataatgtc cggtattttc aagagcgatg agacagtctt
     6001 ggttgagctg tcgaagagac agatctaaga gttcaaaacc agctttatta tttgaaaaag
     6061 tgagtggttt aagaacagtt tttcctggaa cattcaaggc tgtaacatcg tgtttatttt
     6121 tagcgatatc aatgcccaca taaagcatgg gagtacctcc agatatagta tttcaagtct
     6181 acttggttat ccacgaattt tttgccttgt taccttagac gagatcaaac gtctatgcgt
     6241 tatcaaactc attaccaatt gaaacaaaag ctgtggttag agcctttcgg aaatcgtcaa
     6301 gcgattggag gaaatgaact aatccacagt ggcttattcc aagtatacca cttgggcttt
     6361 ggcagtagct aactgcgcta attataatat agggagtaat ctatgtatct tattgaaatt
     6421 ttaaaatcta tcttcttcgg gattgttgaa ggaattacgg aatggttgcc gatttccagt
     6481 acaggtcact tgattttagc agaggaattc atccaatacc aaaatcaaaa tgaagccttt
     6541 atgtccatgt ttaatgtcgt gattcagctt ggtgctattt tagcagttat ggtgatttat
     6601 tttaacaagc tcaatccttt taaaccgact aaggacaaac aggaagttcg taagacttgg
     6661 agactatggt tgaaggtctt gattgctact ttacctttac ttggtgtctt taaatttgat
     6721 gattggtttg atacccactt ccataacatg gtttcagttg ctctcatgtt gattatctac
     6781 ggggttgcct tcatctattt ggaaaagcgc aataaagcgc gtgctatcga gccaagtgta
     6841 acagagttgg acaagcttcc ttatacgacc gctttctata tcggactctt ccaagttctt
     6901 gctcttttac cagggactag ccgttcaggt gcaacgattg tcggtggttt gttaaatgga
     6961 accagtcgtt cagttgtgac agaatttacc ttctatcttg ggattcctgt tatgtttgga
     7021 gctagtgcct taaagatttt caaatttgtg aaagccggag aactcttgag ctttgggcaa
     7081 ttgtttttgc tcttggtcgc gatgggagta gcttttgcgg tcagcatggt ggctattcgc
     7141 ttcttgacca gctatgtgaa aaaacacgac ttcacccttt ttggtaaata ccgtatcgtg
     7201 cttggtagtg ttttgctact ttacagtttt gtccgtttat ttgtataaga aaaaccttga
     7261 aggggcaact cttcaaggtt ttatactctt cgaaaatctc ttcaaaccgc gtcagcttta
     7321 tctgcaacct caaaacagtg ttttgagcag cctgcggcta gcctcctagt ttgctctttg
     7381 attttcattg agctttaaaa tccagtcatg gtaatcccca ataggcggac acctctttct
     7441 ttcttgctta attcttcata gagttgcagg gctatttggc ttatctgact agcatcttgt
     7501 gttttttgag caagactttt tcgtttggta agagttgaaa agtcctcgta gcggattttc
     7561 aaaatgacaa tttttccagc tttttcttgt tgatgtagat tgagagcgac tttttctgat
     7621 agaagagtca gctctttttt gatatcttcc tcagcaagga gaatcttccc gtaggttttc
     7681 tccttgccga ttgatttacg gatgcgattg gatttgactg gagagttgtg aatgccacga
     7741 gcctttcgat acagatcata gcctagtcta ccaaaacggt ctattagggt tacctcagga
     7801 acttcaagta aatcagcacc agtaaaaacg cccatttgat gaagacgttc tactgtcttt
     7861 tttcctactc catgaaattt ggaaatatcc atttgtttga gaaaatcctc agcctgttca
     7921 ggtagaatca ctgtcaaacc atgtggtttt tgataatcac tcgccatttt agctaagaat
     7981 ttgttgtaag aaacgcctgc ggaagcagtt agatggagtt cttgccagat atctttttga
     8041 atgaggcgag caattttgac cgctgacttg ataccgagtt tattttctgt cacatccaaa
     8101 taggcttcgt caatgctcat gggttcaatc aaatctgtat agcgcttaaa aatagctcga
     8161 atctggagtc ccacagactt gtatttctca taattccctg agataaagac agcctgggga
     8221 caacgttcat aagcttcctt ggaactcatg gcagaatgga caccaaaagc tcttgcctca
     8281 taactacagg tagaaacgac tccccgtcca cctgtttgcc gagggtcgct tccaataatg
     8341 acaggttttc ctctgagttt aggattatcc ctgatttcca ctgcagcaaa aaaggcatcc
     8401 atgtcaatat ggatgatttt tcttgacaaa tcatttaaca aaggaaaaat caacatgcct
     8461 agcacctttt tatactcttc gaaaatctct tcaaaccacg tcagctctat ctgcaacctc
     8521 aaaacagtgt tttgagcaat ctgcggctag cttcctagtt tgcttttcga tttccattga
     8581 gtgttactgc ttattttctt ttattatacc cttttttctg aaaaaaagaa aaaaggactt
     8641 tattttttca aaaatataat acagtttgaa ataaaatata gactgtttta gaaaagaaag
     8701 tgtaaaaata gggaattttc acttgttgaa atcggttact atatggtata cttgtcttat
     8761 gaatgtaaca gatgactgtt actagaaaaa agaggacatt aatatggttg ttaagacagt
     8821 tgttgaagca caagatattt ttgacaaagc ttgggaaggc ttcaaaggcg tagattggaa
     8881 agaaaaagca agtgtatcac gatttgtaca agctaactac acaccttatg atggagacga
     8941 aagcttcctt gcaggaccaa cagagcgttc acttcacatc aagaaaattg tagaagaaac
     9001 taaagcacac tacgaagaaa ctcgtttccc aatggacact cgtccaacat ctatcgctga
     9061 tatccctgct ggatttatcg acaaagaaaa tgaagttatc ttcggtatcc aaaacgatga
     9121 actcttcaaa ttgaacttca tgccaaaagg tggtatccgt atggctgaaa ctactttgaa
     9181 agaaaatgga tacgaaccag acccagctgt tcacgaaatc ttcactaaat atgtaacaac
     9241 agttaacgac ggtattttcc gtgcctacac ttcaaatatt cgtcgcgctc gtcacgcaca
     9301 cactgtaact ggtcttccag atgcatactc acgcggacgt atcatcggtg tttacgcacg
     9361 tcttgctctt tacggtgcag actacttgat gcaagaaaaa gtaaatgact ggaatgcaat
     9421 caaagaaatc gatgaagaaa caatccgtct tcgtgaagaa gtaaaccttc aataccaagc
     9481 attgcaacaa gttgttcgcc tgggtgacct ttacggggtt gatgttcgca aaccagcgat
     9541 gaacgtgaaa gaagcaatcc aatgggttaa cattgctttc atggctgtct gccgtgtgat
     9601 taacggtgct gctacatctc taggtcgtgt accaatcgta ttggacatct ttgcagaacg
     9661 tgaccttgct cgtggtacat ttactgaatc agaaatccaa gaattcgttg atgatttcgt
     9721 tatgaaactt cgtacagtta aatttgctcg tacaaaagct tatgaccaat tgtactcagg
     9781 tgacccaacc tttatcacaa cttctatggc tggtatgggt aacgacggtc gtcaccgtgt
     9841 tactaagatg gactaccgtt tcttgaacac tcttgacaac atcggtaact caccagaacc
     9901 aaacttgaca gttctttgga ctgacaaatt gccatacaac ttccgtcgct actgtatgca
     9961 catgagccac aaacactctt ctatccaata cgaaggtgta acaacaatgg ctaaagacgg
    10021 atatggtgaa atgagctgta tctcatgctg tgtgtctcca cttgatccag aaaatgaaga
    10081 acaacgccac aacatccagt acttcggtgc tcgtgtaaac gttcttaaag cccttcttac
    10141 tggtttgaat ggtggttacg acgatgttca caaagactac aaagtatttg atatcgaacc
    10201 aatccgtgac gaagttcttg aatttgaatc agttaaagcg aactttgaaa aatctcttga
    10261 ctggttgact gacacttacg tagatgcctt gaacatcatc cactacatga ctgataggta
    10321 caactacgaa gctgttcaaa tggccttctt gccaactaaa caacgtgcca acatgggatt
    10381 cggtatctgt ggatttgcta acactgttga tacattgtca gctatcaaat acgctacagt
    10441 taaaccaatc cgtgacgaag atggctacat ctacgattac gaaacaatcg gtgactaccc
    10501 acgctggggt gaagatgacc cacgttcaaa cgaattggca gaatggttga tcgaagctta
    10561 cacaactcgt ctacgtagcc acaaactata caaagacgca gaagctacag tatcactttt
    10621 gacaatcaca tctaacgttg cttactctaa acaaactggt aactcaccag ttcacaaagg
    10681 tgtatacctc aacgaagatg gttctgtgaa cttgtctaaa cttgaattct tctcaccagg
    10741 tgctaaccca tctaacaaag ctaaaggtgg ttggttgcaa aacttgaact cactttctag
    10801 ccttgacttt agttatgcag ctgacggtat ctcattgact acacaagtat cacctcgcgc
    10861 tcttggtaag actcgtgatg aacaagttga taacttggta acaatccttg atggttactt
    10921 cgaaaacggt ggacaacacg ttaacttgaa cgttatggac ttgaacgatg tttacgaaaa
    10981 aatcatgtca ggcgaagacg ttatcgtacg tatctctgga tactgtgtaa acactaaata
    11041 cctcactcca gaacaaaaaa ctgaattgac acaacgtgtc ttccacgaag ttctttcaat
    11101 ggatgacgcc ttggatgcat tgagctaatc aagttcttga ataataaaaa ggaaccctcg
    11161 gtcaaacgac tgagggtttt gtgcttggga tagtatgagc aattccttcg gcgcaatatg
    11221 caatgttttt gggaaggaat agtggaccga atctgaaata taatagattg aaactagaat
    11281 agtacacctt tacttctaaa acattcttag aaatcgattt gactgtcctg atcgatttgt
    11341 cctattctta tttcatttta ctatagtccg ctgaaacggc tcaaacagtg ctagaaattg
    11401 actggaattc tctaagtgat ttgttccgat tttatttcat ttcatcataa aaataagatg
    11461 actggctaat tgacaatcat cttgtttgat actgttaata aaattcgcga agtttatctt
    11521 gattttcttt aaaaaatttt tctaaccaat ccataccata agcataacta aaaccttcta
    11581 atagaacaga gaggtcaata gtatcaaatc ccatgtcttt taaatattta aaggtatcga
    11641 atggtgaatg aaagtttttg tatttaataa ttgcaccaat atcttgcaaa tcctgctctc
    11701 tgatactcat catcttcatt cctaacacat actcaatagg gactactaaa acggtcagat
    11761 tctcaaatga gtacaaggat tcgcataaac ttaagggagg ttgtttgttc atatttgctt
    11821 tgcaacatga ttgttgagcc ataactcttc gtggatgtta agattaaact gttttcctac
    11881 acgagcaata atttcattga ttttctgatt ttggtcataa aaagcatcaa catcttgtgt
    11941 ggcacgtaaa ccatgatatt ctaagacata accataattg ttaaagtcag attttcctga
    12001 attaatttct tatttagggc ttggaagacc ggtttcattt tatccatgtt tgtatttctc
    12061 catcaatttt tgaacattgg ttaacttagc aggtttattt aatgaaatca catatttatg
    12121 agttggagta tgctcttgaa aggcatactt caagctaatt ttttgaaaac gggttagttc
    12181 tttggagtct agcaactttt ctacatcttg gtttgttaaa taagaatagt cttcaaaaat
    12241 aacttttcgc aaatagcgaa accaatggct tgcgttgaat tgtgattgtt tggatgcctg
    12301 tatcatataa tcgtaccaat ccattgtctt cctcctataa aatttagttt atattattgt
    12361 agtttatatt caaaaatgta gtttttctta attagctcgt atctatagga tgatactgaa
    12421 aatcttcttg ttgctttaaa tcacaatcga aaaattctgt ttttcatctt agaaaagaat
    12481 gtttagaaat gtaaaatgaa ccttttttct tatccgaaaa ccttactaaa gtatataatt
    12541 taggcagtca attctgtatg ataatgtttg tactatcgtc gagtttttgc ttgattgcct
    12601 aacgagataa attttagaag agttttcggt gtgatttgac aagtttctga ctggaaggat
    12661 agttacacta gtattgttta ttaaaatgag cagatagaga aaatttggaa tctatttgct
    12721 tattatcaat cgttttttta gcttatttgt cttagattgg tatagaactg agctatggat
    12781 taatcttctt ctatcttatc ctgttcctaa atatgttggt agaaaaatga agcagttgtt
    12841 acgagtgtct gtattgggaa aaattttgtc tatagaattc tttaaatgat atgaaggcta
    12901 ggaatgccaa aacactgaca tatttcgttt aaagtctatc cagtctcttc aattgtattt
    12961 gtagaaatgc tatcagtaat atattcgcga acactatgat ttacaacagt gtggtcgtac
    13021 atctttgtaa ctttattata caacaaccat ttacaggtgt aaagttgagc agtgtcttta
    13081 gtaaatttag ggacttgttt tgtcatagtt ttgatacctg tattcgttgt ttcatgagca
    13141 tttgacgttt cttttcatgt aggcatttca acaattagaa tgatattttt ccgaggatga
    13201 acttatatat tgtgactttt tagagttatg atgcctcttg atttgactac cgctatcaat
    13261 ttcatccact tttacagttt catggtttta tgaaccgaaa catctaggta caggttttag
    13321 catcaattga ttgtttttga gccatatgaa gttgaaacgt ggagatgctt ttcttgtgat
    13381 aacgccctat tcaaagagga ataaccgttt ttggagagag ttcagtacta tgtggcgcta
    13441 aatactatat gtaaaacata tattaaacaa gatttaacta aggagaattg taaaaacaaa
    13501 aatgagaatt tcatataaag tttattctag gagtatgtat cttgaataaa aatcgttatt
    13561 taagttcagg gttatgatga atgtttttat aataataaaa tgcagctaga agaaaagtta
    13621 ttttaatata aatcactcaa catagagaga aggcggtttc ctatatggaa gtcgtcttgt
    13681 tttcatattg tctaaatacg agatatctac tacaggttat agttgattta aacaggtcta
    13741 tagatttcta atatattaag gtgaaataat atcttgtaat acattgctat gttctatgaa
    13801 aaaagcgacg atagctaatg cacaagctcc tatacttcca cgatgtttgt tgtaaggtaa
    13861 aatttcaatt tctatattac gagtaaaggg aacgaagtgg agctggtctt ggattttatc
    13921 cctgacttca tgagtgaaag gttgataatt aagcaattga ctgttgatat agattttatc
    13981 agcaggattg atgaggagga gatttgcaat agaagtggct aataaattga ctcctttatc
    14041 aatttgttga cgtaaagcgg agtcgcctaa attataagcc gttaaaaggg tgtctaaatg
    14101 aatgtctttt tcagtcttta caaggctttt tagtacagtt agttgggaat ttttaaataa
    14161 taattgggcg tgtttgatta accaagcatc cgaaatatat gtttgtaaac aacctttttt
    14221 tccgcattca caatattgcc cattcaattc gacaatggtg tgtccaattt ctccgatata
    14281 aggattttta gaggctccta ttttttcttt tgtgaaaaag gaagtgtaaa tacctaatcc
    14341 agcgtgtagg aaaataaagt tatcgggggt attgtgtgga ttaaaaaggt attgtcctat
    14401 agccatacaa tcgatattat tttttacaat aaaaggaaaa ttgaatcttt taattacatt
    14461 taataaatta aaagattccc atatggggtt gtttgtaatg atacttccgg agtctttgtt
    14521 ataatgtcca ggtattgata agccaaatcc aagtaatttt gtttccaaag ggacgtactc
    14581 tatagctgtt tttatcatat tggtaatggt ggaattgatt tctgaaatag gataatcttc
    14641 attcaaaatt tctgtctcga aaagagtttt cccttgtaag tcacatagac tgagaaagat
    14701 acctaggacg tttatttcaa tacctccaac aacatacgga atattatctg tgatagaaat
    14761 agtttttcta cgtcttccag atccggaaaa ctcgctaaat tcatcaccag tttcgtatat
    14821 gagggactgt tcgcttagct cttttatgat gttagtcgtt gttgctggag taagtcctgt
    14881 ttcattaaca atatctgtac gggatgttgc tggatttcga tatagaaact ccagtatagt
    14941 ggctctattt tgtaaaaagg ctgattgttt tgtaatcatt tgtttcctcc tttggtttat
    15001 tttatattaa acataagaaa aaatcaatta aaattattat tttatacaaa gaaaaaaata
    15061 ttgtaaaaac aacaaaaaat atattgacaa cgctttctgt tagtggtata tttaatttat
    15121 aaaaaataaa aaaaggagtt ccggtgatga acaatatttt agcgttttta gaaacaaaag
    15181 tcgctccgtt tggtgaaaaa gttggcaacc aacggcattt gaaagctatt cgtgaaggat
    15241 ttatgatggc aatgcctttg attttagtcg gatctttatt tcttattcta atcagttggc
    15301 ctcaagagga ttttacaaat tggctgaata gtgttggatt gctaagtatc ttgacaacta
    15361 tgaatcagtc aacagtagcg attatctcct tggtcgcttg tttcggtatt gcctacaggt
    15421 tgtcggaagg atatggtaca gatggtccgt cggcagggat catagcctta tccagttttg
    15481 tattgatggc acctcgtttt tcgagtatgg tttatgataa aaatggggag caggtcaagc
    15541 agttatttgg cggcgcaata ccattttcta gcctgaatgc atcttctttg tttatggcga
    15601 ttactattgg attggttaca gcagagattt atcgtatgtt tatccagcgc ggaattacga
    15661 taaaaatgcc aagtggtgtc ccagatgtgg taagtaaatc attttcagct cttttacctg
    15721 gctttactac ttttgttttg tgggctctgg tcttaaaagg tcttgaagcg gcaggagttg
    15781 caggaggtct caacggactc ctaggtgcaa ttgttggaac accgcttaag ttaattgcag
    15841 gaacgcttcc aggtatgatt ctatgtgtta ttgtaaactc attcttttgg ttctgtggag
    15901 ttaatggggg acaagtttta aatgcttttg tagatccagt ttggttacaa tttactacag
    15961 aaaaccaaga agctgtggct gcaggacaaa cactccaaca cattattaca ttaccgttta
    16021 aagatttatt tgtatttatt ggtggcggtg gagcgactat tggtcttgcg atttgtctct
    16081 tcctatttag taagagtcgt gcgaataaaa cattaggtaa gctagctatt ataccgtcta
    16141 tttttaatat caatacagct attctattta cgtttccaac agttttaaat ccgattatgc
    16201 tgattccgtt tattgctact cctacaatca atgccttaat tacctatgta tcaatggctg
    16261 taggattagt accctacaca acaggtgtaa tccttccgtg gacaatgcca ccgatcatag
    16321 gaggcttcct tgcgacagga gctagttggc gaggagctct attacaagtt gttttgattt
    16381 tggtttctgt agcaatttat tatccattct tcaaaattgc agataaacgc aatcttgaaa
    16441 aagaaaaagc tactgttgga gggaaataag atggttatca gagtatttga tcagcagaaa
    16501 aatacttatt ctagctttgc cttagaggaa ttaagttact atataaatcg ggtctttaag
    16561 actgacatag aacttgtcga ggagaaggaa gcggatattt ttgtaggatt agtcaataaa
    16621 gaggatagaa aagaccatgt tcttatctca ttagacaagg gtaaggggag aattgagtct
    16681 aatacaattg taggtttgct tattggaatt taccgaatgt ttcatgaatt tggggttgtg
    16741 tatactagac cagggcgcgg acatgacttt gttccagagt tacgatttga agatttttta
    16801 gataaagagc tatctataga tgaaacagcc agttactatc ataggggagt atgtatagag
    16861 ggagcagatt catttgaaaa tatactagat ttcattgatt ggctacctaa gattgggatg
    16921 aacagttttt tcattcagtt tgaaaatccc tattcttttt tgaaacgttg gtatgaacat
    16981 gagtttaatc catacctaaa taaagaaaaa ttctcaaatg aattagtaca agaattgagt
    17041 gataggttgg ataaagaatt gcaaaaaaga ggtcttattc atcatcgtgt tggtcatgga
    17101 tggacaggtg aggttttagg ttactcttca aaatttggct gggaatcagg tcttagtatt
    17161 tcagaggaga agaaacccta tgtcgctgaa ataaacggga aacgagaatt atttaatacg
    17221 gctccgattt taaccagtct ggatttttca aatccagatg tggcggataa gatggtagaa
    17281 attatcaagg attatgccaa gaaaagacct gatgttaact acttacatgt atggttgtcg
    17341 gatgctcgta ataatatttg tgaatgcgaa aactgtagac aagaattggt ttcggatcag
    17401 tatattcgta ttctcaatca attggatagg gctttaacga gtgagggatt agatacaaag
    17461 atttgttttc tgctttacca tgagttgtta tgggcgcctc agaaagaaaa attagataat
    17521 cctgaacgct ttaccatgat gtttgcaccg attacaagaa catttgaaat gagttatgca
    17581 gatgtagatt ttgacaattc catacctacg cctaaacctt atctgcgtaa taaaattata
    17641 cttccgaatt ctcttgagga aaatttatct tatctttttg agtggcaaaa aacatttaaa
    17701 ggagatagtt tcgtatatga ctatccttta gggcgtgctc attatggcga tttaggctat
    17761 atgaaaatta gtcaaaccat ttacagagat gtatcttatc tttctaacct acatttgaac
    17821 ggttacattt cgtgtcaaga attacgtgcc ggattccctc ataattttcc taattatgtt
    17881 atgggggaaa tgctctggaa gaagacaaga agttatgaag aattgattga agaatacttt
    17941 tctgctttgt atgggtcaaa ttggcagtct gttgttgaat atttagaaaa attatccagt
    18001 tattcctcat gtgattattt taatgcaatt ggcagtcgtc aaaatgatgt tttagcgaat
    18061 cattattata tagcttacaa tctagctgat aattttttgc caattattga ggaaaatatt
    18121 tctaagttat taaatagtca aaaggatgaa tggaaacagc tcagttatca tcgtgaatat
    18181 gttgttaaga tggcgaaggc tttatatctt caagcaaccg gaaaaacaag gcaagctcaa
    18241 gatgaatgga gaaatgtgtt gaattatatc cgtgggcacg aattgctatt tcaatctaat
    18301 ttggatgttt atcgtgtaat tgaagtagca aaaaattacg ctggtttcca cttataaatc
    18361 ataagtatag aaaatgaacc aaggtattca gagaagattg atcctaaata ttatgaaatt
    18421 taaggatttt taagatattt agggtcgact ttctatttat atcgtagcga agtcatttta
    18481 ataatgatgt gtaaaagatg gatcaagatt gaggaggaag aaagatgaaa tcaaaagaag
    18541 aaataaatat gcttggtttt acaattgtcg cttacgcagg agatgcaagg tcagatttga
    18601 tggatgcttt ggcgtttgcg agagatggat attttgaaca ggcaagagaa ttggttgagt
    18661 ctgcaaacga ctcaatagtg tctgcccatc gagaacagac taatttatta gcggaggagg
    18721 catctggaga taattttgaa gtgagtttta tcatgattca tggtcaagat accttgatga
    18781 caacgatgct attgtatgat caggtcaagt tttttattga tgaatatgaa cgaattcgaa
    18841 agattgaaga acatattggt ttgcaatgag gattagtcat ggaaaattta caggttaaag
    18901 ccttaccgaa ggagttttta ttaggagctg ctaccgctgc ttatcaagta gagggtgcaa
    18961 ctagggtaga tggcaaagga acaaatatgt gggatgttta tttgcaagaa aacagtccgt
    19021 tcttaccaga tccagctagt gatttttatt atcgttacga agaggatata actttggcgg
    19081 cagaacatgg tttgcaggct ttgcgtttat ctatttcttg ggttcgtata tttcctgata
    19141 tagatgggga gcctaatata ttagctgttc gttattacca tagagtcttt cagtcttgct
    19201 taaaacataa tgtgattccg tttgtttctt tacatcattt tgattcgcct cagaaaatgt
    19261 tagaaacagg ggattggttg aatagagaga atattgatcg tttcatacga tatgctcgct
    19321 tttgtttcca agaatttaca gaagtcaagc attggtttac aatcaatgaa ctgatgtctc
    19381 ttgctgcagg tcaatatata ggaggtcagt ttcctccaaa tcatcatttt caattatctg
    19441 aagcaattca agcgaatcat aatatgttgt tggcgcatgc tcttgcagtc ctcgaatttc
    19501 atcaattagg aattgaggga gagataggtt gtattcatgc tttaaagcca ggctatccta
    19561 ttgatgggca aaaagaaaat attttggcag ctaaacggta tgatgtttat aataataaat
    19621 ttctattaga tggaactttt ttgggctact acagtgagga cacgcttttt cacttgaatc
    19681 aaatattgga agctaataat tctagcttta ttattgaaga tggtgattta gaaattatga
    19741 agagagctgc agctcttaat acgatgtttg ggatgaatta ttatcgttca gaatttattc
    19801 gtgaatacaa aggtgaaaat agacaagaat ttaattcaac aggaataaaa ggacagtctt
    19861 cttttaaatt aaatgctcta ggtgaatttg taaaaaaacc tggtattccg acaacagatt
    19921 gggattggaa tatttatcct caagggttat ttgatatgtt gcttcgtatc aaagaagaat
    19981 atcctcaaca tccggtcatt tatttaactg aaaatggtac agcccttaaa gaagttaagc
    20041 cagagggcga gaatgatatt attgatgaca gtaagagaat ccgttatatt gagcaacatt
    20101 tacacaaagt tttagaggct cgagatagag gagtcaatat tcaaggctat tttatatggt
    20161 ctttgcaaga tcaattttct tgggcgaatg gctacaataa gcgatatggt cttttctttg
    20221 ttgattatga aacacagaag agatatatta agaaaagtgc tctttgggta aaagggctaa
    20281 aacggaatta aggttagcga tttgactgat gtttaatata ttttaactat gagcttaaat
    20341 tttttacagg aggagttttt atggataagt tagtcgctgc cattgaaaag caacaaggga
    20401 aatttgaaaa aatttctact aataattata tgatagctat taaagatgga tttattgcta
    20461 ctatgccttt aattatgttt tcaagctttt tgatgattat tattatgatt cctaaaaatt
    20521 tcggagtaga gttaccgagt ccagctattg cctggatgag gaaagtgtat atgctaacca
    20581 tgggagtttt gggtattatt gtttcaggga cagttgcaaa gtcattggct ggaaatgtta
    20641 atagaaaaat gcctcctgga aaggtaataa atgatacttc tgcaatgttg gcggccatat
    20701 gtggctatct tgtattaact gtaacgcttg tagttgatga gaaaacggga tctacaagtt
    20761 tgtcgacaaa ctatttagga tctcaaggat tgataacttc gtttgtcagt gcctttatta
    20821 ctgtaaatgt ttaccgattc tgtattaagc gagacattac tattcattta cctaaggaag
    20881 ttcctggggc tatatcacaa gcttttagag atatttttcc tttttctttt gttttactta
    20941 ttagtggttt gttagatatt gtatctcggt ttagtttaga tgttcctttt gcccaagtat
    21001 ttcaacaact attgactcct atttttaagg gggcagaatc atatcctgct atgatgttga
    21061 tttggtttat gtgtgctttg ctttggtttg ttggaattca tggaccatct attgtcttac
    21121 ctgctgttac agctttacaa ctgagcaata tggaagagaa tgctcaactt cttgcaaatg
    21181 ggcagttccc ttatcattct ttaacaccta atttcgggaa ttatatcgct gctattggag
    21241 gaacgggggc tacctttgtt gtaccattta ttttgatttt ctttatgcgg tctaaacaat
    21301 taaaatcggt aggtaaagct acaattactc ctgttttatt tgcggtaaat gaacctcttc
    21361 tatttggtat gcctgttatt ttgaatccct atctttttgt cccttttttg atgactccac
    21421 cagtgaatgt atttctagga aaggtattta ttgatttctt tggaatgaat ggattttata
    21481 tccagttacc ttgggccttt cctggtccct tgggattgtt aattggaacg aattttcaac
    21541 ttatctcctt tgtattttta tctttgatgt tagttgtcga catattgatt tatttgccat
    21601 tctgtagagc gtatgataga cagttactgg tgaaagaaga tattgcaagc tcaaatgata
    21661 ttattttaga ggaggataca agtgaaataa tgcctggtga gatagatgta ataaaaagta
    21721 aggagttgaa agtactggtt ctttgtgcag ggtctggaac aagtgcgcaa ttagccaatg
    21781 caattaacga gggcgctcaa ttagcagaag ttagagtgat tgcgaattca ggagcgtacg
    21841 gagctcatta tgatattatg ggtgtttatg atttaattat tctggcccca caagttcgga
    21901 gttattatag agagatgaag gtggatgcag aaagattaga tattcagata gttgctacca
    21961 gaggaatgga atatattcat ttaacaaaga gtccaagtaa agccttacaa tttgtattgg
    22021 agcattacca agctgtgtag taagtttttc catcttttat ttgagtaaag attttgctta
    22081 cagataggct tggatttaaa aacgttcccc cttttttaat ataagaatcc ctctttcaca
    22141 attgtaaaaa gagggatttt gtattttatc tcttagacca agttctcttc ataaagagaa
    22201 ggaggattgg gtaaatctcc aagcgccctg caatcattgc aaaggatagg agaatttttg
    22261 agatgggact aaagattgag aaactagaag tggttcctag aataggcccg atattattga
    22321 aacagctaaa gacagcgctg gtcacgacca gaaaatcatt gctatctagg ctgacaataa
    22381 agataagcgc tagcaaaatc atagcataga tgacaaagta cttgagaatc ttatgctggg
    22441 tatctttgtc aatcaccgtt ttattaacat ggagggtcaa aacacggtgg ggcgatagga
    22501 ttgacaaaat ttggtttttg gcaatttttg aaaggatgag gcctcgaata atcttgagtc
    22561 cacctgcagt tgatccagca gagccaccga ttgccatgag gaaaaggagg ataaactggg
    22621 agaagagggg ccagttggta atatctccat atccaaaacc agttgttgta atgatgttgg
    22681 aaacctggaa gaaggtcatt tcaaagctct ttgaaaaccc tgggtagagg tagagggtgt
    22741 tgaggctaat caagcctgta gaaaccagta caatgaccaa gtaagcccta agctcttcat
    22801 ctccaaagaa ggccttgatg cgacggagca tgaggtagta gtagaggttg aaatttactc
    22861 caaaaaccag aactccgata ctgaccagat aggtaatcag tgagctgcca tagtgggcaa
    22921 ttccgtcgtt atagacggta aagcctccag ttcccgctgt ccccatagca atgacaaaac
    22981 tatcgtagag aggcatacca gctagataat agatgatgac aaagagggag aagagagcta
    23041 gataaaggag atagagaatc tgggcagtgt tttttagttt ggatacaacc ttgccaaaaa
    23101 caggacctgg aacctcagcc ttcatcacct ctaggtggct atttttggca ttgtccataa
    23161 tagcaagtgc aaaaacaagc actcccatcc ctccaatcaa gtgggtaaaa cttcgccaga
    23221 agaggaggga acgactgaga actgaaacgt cgttcaaaat acttgctcca gtagtcgtaa
    23281 agccggaact aatctcaaaa aaggcatcaa taaggctggg gatttgccca gaaaagacaa
    23341 aggggagacc accaaagaaa gaccaaagga tccaacagag ggcaacgatc aagactccct
    23401 ccttggcata aatccgttga ttttttggct tctgtaaact ccctgaaccg cctaacaata
    23461 cgagaatccc tatggtcgaa aagagggctg taaagacttg gctcgattca cggtaataga
    23521 cagcgatagc cacaggaacc aagaggagaa cagcttcaat caaaagtaac tttgaaagga
    23581 ggtaacgaat catactttta ttcatttctt acctcgcaat caagtcataa atcttggtga
    23641 tgtttggcaa caaggttgtt actaggagct tgtctccaac ttccaacata tcctccccag
    23701 ttgggaaaat agtcttgccc tttcgaataa tggctgcaat aagaacccct tttttcaatt
    23761 tcagttgaga aagaggtttg gcagtcattt tattggcttc cttgatatgg aattgcaggg
    23821 tttcgatttg gccattggct agatggtgca tggcttgaag gtctgaatac tgggcattaa
    23881 ctcgaccacg aataaagtgc ataatcgtat ctacagcgat gcttttaggt gtgatgatac
    23941 ttgaaaaatc aggcgcattg ataatctcga ggagactggt acgattgacc ttagtaatat
    24001 ttttctgtac acctaccctg tcaaggaaca tagatgtaat cagattttcc tcatcgactc
    24061 ctgttagagt cgcaacggca tcatagtgtt gagcactttc ttccagcagg atatcttttg
    24121 cggttccatc tccttgaacg atgtagagat ttgggaattt ctcgctaaag aagctggcga
    24181 tttcaggatt gatttcaatg acttttgtat cgatacgact atctttgaga ataccaagta
    24241 gataataggc aattctacct gccccaacga tgagaaggct cttcacggcg cgtgatttaa
    24301 aataattatg gaagagtatc atatcgacac ggttaccagt gacaaagatt ctatctttat
    24361 cctgtacagt catgtcaccg cttggaatga taatttgatg atccctctct atcgcacaga
    24421 caatgacatt accaaatttt ttacgaaaat cagaaatggg catttggcaa agaccgctgg
    24481 tggacttgac gacaaattcc atgaggctaa cgcgtccacc agcaaagcgt tcgacagaca
    24541 gggcgttggg gaagtcaatg atattcgcga tagcacgggc agccaagagc tcaggattaa
    24601 cgataagaga aaaaccgaga atattctttt ccttgaaata agagttagaa tattcagggt
    24661 tccgcacccg aacgatagtt tctttagctc ccattttctt ggctagaact gctgcaatca
    24721 tgttgacttc atcgtgctca gtcagggcga taaagatatc acaatcttgg acgctggctt
    24781 gctcaagaat ggcaaaatcg gccccgttac caaggatacc aatgatatca aagcgactga
    24841 caatatgatt gagaacagct tcgtcttgct caatcagcaa aacatcatgc ttttctgcaa
    24901 ccaaggagcg acagagggca aaaccaactt ttccccctcc gacaaggata attttcataa
    24961 taaaacctac tttttcatga tgtaactatc ataccctttt tcaagaaaaa atgcacctac
    25021 tagctaataa caagagcttt tagtgaaaat tcgctataag ataaaactat accctaacca
    25081 attgaaatag ctattagcga ctttctctga aatatggtat gataaaggat atacaaggag
    25141 ataaaatgaa taataattta ctggtattac aatcagactt tggtctggtt gatggtgcgg
    25201 tatcggctat gattggagtg gctttagaag agtctccaac cttaaaaatc catcacttga
    25261 cgcacgatat cacgccttat aatatttttg aggggagcta tcgtctcttt cagacggtgg
    25321 attactggcc tgagggaacg acgtttgtat cggttgtcga tccaggtgtc ggttcgaaac
    25381 gtaagagtgt agttgccaag actgcaaaaa atcaatacat tgtcacgcca gataatggga
    25441 cgctttcctt tatcaagaaa cacgttggca ttgtagccat tcgtgagatt tctgaggtgg
    25501 ccaataggcg tcaaaacaca gagcattctt ataccttcca cggtcgtgat gtctatgcct
    25561 atactggtgc taaactggcc agtggtcaca ttacttttga ggaagtaggg ccagagctca
    25621 gtgtggaaca gattgtagag cttccagtcg tagcgaccat catagaagat catctggtga
    25681 agggagccat tgatattctg gatgtgcgtt tcggttcgct ttggacctct atcacacggg
    25741 aagaatttta caagttggaa ccagaatttg gtgatcgttt tgaagtgacc atctatcatg
    25801 ctgatatgct ggtctatcaa aatcaggttg tctatggcaa atcatttgca gatgtgagaa
    25861 ttgggcaacc catcctttac atcaactctc tctatcgttt aggtttggct atcaaccaag
    25921 gttcctttgc caaggcctat aatgtaggtg tcggttcatc ttggaccatt gaaataaaga
    25981 aaatagaagg ataaaatagg agaatagtat ggaaatcaaa tttacaatta aacaagttgt
    26041 tgctgtcgga attggcgctg ccctctttgt cgtcatcggg atgatcaaca ttccaacccc
    26101 tgttccaaat acaagcatcc agcttcagta tgcggtacaa gcgctacttt ctattatttt
    26161 tggaccgatt atcggtttgc ttgttgggtt gattggtcat gcaatcaagg actctcttgt
    26221 tggttatggt ctatggtgga cttggattat cgctagcgga ctctttggtt tagttgtggg
    26281 actttttaga aagtacgttc gcgtgatcaa tggtgttttt gactggaaag atattcttat
    26341 ttttaacctc attcaactac ttgcaaatgc ccttgtttgg ggtgtcttgg caccacttgg
    26401 agatgttgtg atttatcaag aagcggcaga aaaagtattt gcacaaggaa ttgttgcggg
    26461 aattgccaat ggtgtatctg tagctattgc aggaactctt ctcttacttg cctatgcagg
    26521 aacccaaact cgtgcaggaa gtttgaaaaa ggactaatac tcaatgaaaa tcaaagagca
    26581 aactaggaag ttagccgcag gttgctcaaa acagtgtttt gaaattgtgg ata
//
LOCUS       DAVAZT010000029        25983 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVAZT010000029 DAVAZT010000000
VERSION     DAVAZT010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25983
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.029"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..90
                     /locus_tag="VQT45_001142"
     CDS             <1..90
                     /locus_tag="VQT45_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET2359470.1"
                     /translation="FSTTYRNHRKRFGLRMNLSAGIINHELGF"
     gene            complement(253..504)
                     /locus_tag="VQT45_001143"
     CDS             complement(253..504)
                     /locus_tag="VQT45_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359471.1"
                     /translation="MPKTKTLAELADVILWSFDFANDHAHAFFMDNVEWSHADSYFLS
                     FVSDDVEERYIENVYLDSLSVKQKFKFIFDFGDEWRFEC"
     gene            complement(794..2674)
                     /locus_tag="VQT45_001144"
     CDS             complement(794..2674)
                     /locus_tag="VQT45_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET2359472.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIQGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(2668..3537)
                     /locus_tag="VQT45_001145"
     CDS             complement(2668..3537)
                     /locus_tag="VQT45_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2359473.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPDLENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNILCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQDVKKAVDNFVDTYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(3621..6266)
                     /locus_tag="VQT45_001146"
     CDS             complement(3621..6266)
                     /locus_tag="VQT45_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HET2359474.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDERFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELIVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAFRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVFRYYNMSQENVHISEHQQTILDLLE
                     RPYPVHSGPLDPQEIRTEFIKKEEI"
     gene            complement(6357..7637)
                     /locus_tag="VQT45_001147"
     CDS             complement(6357..7637)
                     /locus_tag="VQT45_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HET2359475.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSIDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            7808..9892
                     /locus_tag="VQT45_001148"
     CDS             7808..9892
                     /locus_tag="VQT45_001148"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HET2359476.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGKAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKENKWLDIHTEQNHSHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPNH"
     gene            complement(9932..11611)
                     /locus_tag="VQT45_001149"
     CDS             complement(9932..11611)
                     /locus_tag="VQT45_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HET2359477.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNLDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFDCRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIYVLAFQAGETEKRLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            12366..13595
                     /gene="arcA"
                     /locus_tag="VQT45_001150"
     CDS             12366..13595
                     /gene="arcA"
                     /locus_tag="VQT45_001150"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HET2359478.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELILSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGNLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            13653..14669
                     /gene="argF"
                     /locus_tag="VQT45_001151"
     CDS             13653..14669
                     /gene="argF"
                     /locus_tag="VQT45_001151"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HET2359479.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            14834..15781
                     /gene="arcC"
                     /locus_tag="VQT45_001152"
     CDS             14834..15781
                     /gene="arcC"
                     /locus_tag="VQT45_001152"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HET2359480.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVIVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            15990..17501
                     /locus_tag="VQT45_001153"
     CDS             15990..17501
                     /locus_tag="VQT45_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HET2359481.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYEA
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNTWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            17523..18854
                     /locus_tag="VQT45_001154"
     CDS             17523..18854
                     /locus_tag="VQT45_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HET2359482.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAEDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(19260..19550)
                     /locus_tag="VQT45_001155"
     CDS             complement(19260..19550)
                     /locus_tag="VQT45_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359483.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(19538..19789)
                     /locus_tag="VQT45_001156"
     CDS             complement(19538..19789)
                     /locus_tag="VQT45_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HET2359484.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGDQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            complement(20188..21072)
                     /locus_tag="VQT45_001157"
     CDS             complement(20188..21072)
                     /locus_tag="VQT45_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET2359485.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(21217..22368)
                     /locus_tag="VQT45_001158"
     CDS             complement(21217..22368)
                     /locus_tag="VQT45_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HET2359486.1"
                     /translation="MAIFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHRCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPQALTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIEHENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIVEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(22514..24280)
                     /locus_tag="VQT45_001159"
     CDS             complement(22514..24280)
                     /locus_tag="VQT45_001159"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HET2359487.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGCAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDSGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            complement(24337..>25983)
                     /locus_tag="VQT45_001160"
     CDS             complement(24337..>25983)
                     /locus_tag="VQT45_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HET2359488.1"
                     /translation="NYRTDKTAMWALSGNFDASKSWKKEELELANWISKNYSINPVDN
                     DFRTTTLTLKGHTGHKPQINISGDKNHYTYTENWDENTHVYTITVNHNGMVEMSINTE
                     GTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVDYNGDPNRAVDGNRNGNFNSGSVTHTR
                     ADNPSWWEVDLKKMDKVGLVKIYNRTDAETQRLSNFDVILYDNNRNEVAKKHVNNLSG
                     ESVSLDFKEKGARYIKVKLLTSGVPLSLAEVEVFRESDGKQSEEDIDKITEDKVVSTN
                     KVATQSSTNYEGVAALAVDGNKDGDYGHHSVTHTKADSNAWWQVDLGEEFTVSKVDIY
                     NRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDKVVDGLLSLKVPSVGAKLVKIELKSAA
                     IPLSLAEVEAYGSKRTPKKLSNIALTKETRQSSTDYNGFSRLAVDGNKNGDYGHHSVT
                     HTKGDSPSWWEIDLAQTEELEKLIIYNRTDAEIQRLSNFDIIIYDSNNHEVFKQHIDS
                     LESNNLSIDLKGLKGKKVRISLRNAGIPLSLAEVEVYTYK"
BASE COUNT         7364 a         5808 c         5067 g         7744 t
ORIGIN      
        1 ttttcaacaa cctatcgaaa tcatcgtaaa cgcttcggat tacgaatgaa tttgagtgct
       61 ggtattatca atcatgaact aggattctag ttttgcagga agtctattga aatactaagc
      121 ctacacagac tgatttcaat tttaccattc ttcatagtca aaaccatcat aatctggata
      181 ttgttctggc aacgttccaa ccgaacgtac gagataagct tcttcgtcct ctgtctcgat
      241 ttctctcagc acttagcatt caaaacgcca ttcatcaccg aagtcgaaaa taaacttaaa
      301 tttttgtttg acacttaggc tatccagata gacattttct atgtaacgtt cttcaacatc
      361 gtcactaaca aagctaagaa agtaagaatc tgcatgactc cactcaacat tatccatgaa
      421 aaatgcatga gcatgatcat ttgcaaaatc gaaactccat aaaatcacat ctgctagttc
      481 cgctaacgtt tttgtttttg gaatctatat atgtcggtag caaccttttt taatttgacg
      541 gaaatgatcc aagcttctac agatgctggc ttttcagctt ctatttcttg ttttactaat
      601 tttaactgta gcatttgaaa ccagataatt cttctgtttc acgcgaaaca ccctgcgcca
      661 agcaaggtgt tcttgttttt atactcaatg aaaatcaaag agcaaactag gaagctagct
      721 gcaggctgct caaaacactg ttttgaggtt gtagatggaa gctgacgtgg tttgaagaga
      781 ttttcgaaga gtattaagtc gtataaatcg tcgaagctgt cgcaatggta tgccactggt
      841 tagctgtagt tgctgcgaaa tccttgtctg cgtagaagtc agtaaatggt aggatttcaa
      901 cttccagctc gtcgatgcgg tcaagctggc cagccagata aacctcgata cggctttctg
      961 ctcgtttgat gcgttgcaag agtccgccca tacggatgtc aactgtatcc aaaccaaaga
     1021 ccttgttttc tttcagccat tggtgactaa agagggcatg gaagtcttca atttggcttc
     1081 taagttctgg taattcttgt ctggcgattt gttgtaaact ttctttatca tccgcttggt
     1141 aggcctgacg aatgcgtcgt cccacatcta ctttgctact taaaatagca ttcaactggg
     1201 cctgagtttc aaagagataa gcatagtttc cagctttttc tttaatgtta gcaagcgtct
     1261 cagcagcctg agcgaagtgc ggtttgtcct gttcaggtgt catgtgttga tcaagaatcg
     1321 gacaaagaat atcctgataa aaaacatagc ggttgggatt gataccgctg agattgcctg
     1381 gtaggtctgg taagaggttg gcaaggtcaa tctgcataaa atcctcaacc gttagaccag
     1441 tattggtctt gaagtgcgca gacaaaccat ctaggtcatt gcgatagctg agttctgccc
     1501 agatttgcaa gcttggtagg atagagaact gggcagtttc accaccattg tctccccaac
     1561 ccgttacgat gacttcttta atctgattgg cacggcaggc tttattagcc tcgatagcca
     1621 ctagacggct aaaatggttg tgaggtgtaa agccaatcca cttccaagct ccccctgcaa
     1681 atgcaaggtc atggctaatc ttgtgatgat tgcggaaatt acggttgtat ttttcctcgc
     1741 tatcctgata ataatcccag taaaccagag tcacacggtc tttgagacgg tctaggtaga
     1801 cacgagtttc ctctggaatt tccacatcac ggtcgtactg gccatccgct gacatgagtt
     1861 tgaagaacat atcactccac atctggcagt ggaaaccata tttgtcagca atatccagca
     1921 cgcgctccaa gtgttggcac atgaggagac tacgatccac aacaccgttc aaaatcaggt
     1981 agcgtcccaa accaaccaag tgggcttcgt ccatcccgat attgaccttg cgagtcttca
     2041 gtttagacaa cgtggcaaac atgccatcaa tcaggtcata aaccttttct tcgccaatga
     2101 gaagaatgtc ctctacatca cggagctcct gcacttcctt gacaccccat ttgacaaagg
     2161 ccgacaagtg ggccaaggtc tggatgcatg gtacaaaggt catgtcaaac tgttgagcat
     2221 aggcttcgat ttcctgcaac tcctctgctg aataagctcc acggaaatag ccaaagtaag
     2281 gctgcccttc aatctggtaa gtgtcttcca tgtaaagttc aaaggttgag tagcccatga
     2341 gagccaagac ctcaatcatc tgcttggcag aagccacatt cagcaccgca tttcgagaac
     2401 agtcaaccat gtaagccaaa tcttcgtaag ctgcttgttc ctcaatctct actttatcag
     2461 cttctgctag aactgttacc aacaaggata aggcacgata aagttggtga ggtttgcggt
     2521 aggtcaattg atagtgacct tcctcaccct ggatagagat agaggcttgg tcagactgag
     2581 tgacagccac ttccacatct ggtagagaaa tatgaccttt taaaacctca atagcttgcg
     2641 tttgtttggg actaagtcct gtaaatctta ccattgcttt tcctcctgta gccagttgac
     2701 aagagcaccg tagagattgg catctgcgtg ataggtgcag gcctggataa ctggtgcgac
     2761 cgtgtattct tcgtaggtat cgacaaagtt atcaacagcc ttcttgacat cttggataaa
     2821 atctggattt tgactgatag agccacccag actgatgaca tctggatcga tcagatactg
     2881 gatattgagc aagccttgcg ccagattgcg gttcatgcgc tcaatggctt cttgacaaag
     2941 gatattacca gctgcggcct cttggtaaat cttgcgaccg tcccaatcag tatgaccaga
     3001 tttttcaatc acgtatcgta ccatattccc agttgatgct agttgcgacc agttattaag
     3061 tttttcagca ggggcaaggg ttgtcatgta gccaaattct ccacccaagc cgtggcgacc
     3121 tcgatgaagt ctaccattga taatcatggc tccgccaatc cctgtcccaa tcacgacaca
     3181 ggctgcattt tcaagatctg gatgagctag tagttcactg agtccaacgc agttggcatc
     3241 attttctaaa tggacaggta gctgataaga gctaagcgcc tcataccaag aaaagccatg
     3301 gatgtagggc accgcactga agccatcaat cacacctgtc tcttgattga ctgcacctgg
     3361 aacgctcata gcaatcccac tgtaatcctg ttctgacaag cgttgatcta gccacgctag
     3421 taaatcctcc aagttttcag gcgttgaaat acttgtctta tccagtattt tcccatcagg
     3481 agtcagactg gcaaacttaa tcccagtccc tccgatatca atcgttgcaa tggtcattgt
     3541 ttttaccata aaaaggggcg aatcagcagt tagttcttac tttttcgccc ctcctttctt
     3601 ttgatgttta ctttttgaaa ttaaatttct tcttttttga tgaattctgt acgaatctct
     3661 tgtggatcca atggtcctga atgaactgga tatggtcgct caagtaagtc aagaatggtt
     3721 tgttgatgtt ctgatatgtg cacattttct tgactcatat tatagtaacg gaagacatag
     3781 ccttcttcat tttccgccac tttaaaggct gttggacaaa cttgcggtat gctgagaaca
     3841 gaatggctca agaggctacc agtcgcaacc acgcttcctt cctgtctagc aagctgaagg
     3901 ctggtaaacg gtgtctgcaa ggctttggca cgacggaaag ctgaaaagcg ttcttgggct
     3961 tggtggcatt caagtgcaaa ctcgacttca aactcacgca agcattgtgc ttctggcgtt
     4021 gggaagtagc cccagtcacc tagctcacct gatgcacgca aaatggtcac ggcaatggtg
     4081 ttatccccaa ggatttcgta ttcattcaat cccttattgg atacagtcac ccctttttca
     4141 tcgtcataca gactgacaaa agcttgttgg tgttgaggat tttcaggatt ttcccatgaa
     4201 gcagctggtt tgtttggtcg tgtcaccacc tcatagatac tttcagaatc attgcttgga
     4261 cgcgtgttat gagtcttgac caagagacgg atacggtgat ccttggcagt gttagtaaag
     4321 cgagtcttga agcggatttg tggattgtca acaaagacaa tcaactcagt ttccagagga
     4381 atgtttgtca attcttctga ccgtccagcc tcacgcttca taaactcgat gataccttgt
     4441 tgctcttctt ctagcttttc atccgcactg acaggcacgg tcaattcatg tttgagcaag
     4501 attttagcat agcgatctgt gttttccaag acctcgtggc ccttaagctc tgcaaagatt
     4561 ggctctgttc cttttggttg gaaatagata tactcgtttc cgatgtcccc acggtcttcg
     4621 aagcggataa agtcttcata ggcttcgtga gttgtcttgt catatactgt gatattgtca
     4681 tccacactca ccgttacgaa tggtgtatca atcactccgt tttggtaaat accctcacgg
     4741 tgttcttgtt ttccttccag caattggaag gttgtccaag aaagcggcgc taggtgaact
     4801 ggaatggtca cgcgcacttg tcgagcaata cgagcttggc ggaacttgtc ttttggtaaa
     4861 tcgtactcaa aattagctcc gaggtcttcg attgtagcct ctacaggacg accatccaag
     4921 tcctccacac ggtaacttgg taagataaga gcagccatct ttttgtagcc ttctgttggg
     4981 tgcaattcct tgaaatcaca agtcgccaca tcaatcactg tgctgacagt atcgacctta
     5041 tcatgcaagc ctgtgttaat gacagtaaag agatagtcac tttgagcctt atccgtagca
     5101 attttaccct tccactcgtt gagcaagtta cttttaacaa agtttcctac ttggttgacc
     5161 ttggcaaaac gcgtttccat ctcgcggtga acttcgtcca cgctacagcc acagatacta
     5221 tcatgtggcg cattctgcaa aagtgttttc caagcatagg tcaactggtc cttgtggttg
     5281 tgtccaccag tgataatagt caagggttct accacttgct ctaggaggtt gctattttct
     5341 tggaaggctt gttttaggta aatgcgggat gaagaagtgt tggcaagtgt gtaccagcca
     5401 tctgtttcct gactggtcaa ctcgcctgta acagttgata agtgttcagg aagcgcacct
     5461 tctacagctt gaacatattc atcaaaagaa ctatgaacaa agattacatc cgggaagagt
     5521 tcatttgcca cacgaatggc ttcgctcaga tttttctgta caggctggtg gtcacagccg
     5581 ttcatcatca accattggtt ggtcgaagcg taggcacgca catctgacaa tttttgtttc
     5641 cagaaggtca aggcctcatc tttgtcaact gggatttcat tcccattact gtaccagttg
     5701 gcaaagagaa tacctaaaac acgactacca tccacaccct gccagtacat ttctgaaaac
     5761 tgggatgtaa accgctcatc ttcaaggact tggttgtcaa atccaatcgg cttcacacca
     5821 cgaccaaagg ctgccacgtg aatacctgat ttttgaagga tttgaggagc ttgtcccata
     5881 tttccaaagg tatctggaaa gtagccaatc tgggttgatt taccccattt ggcagcttct
     5941 tgttgaccaa tcaaggtatt gcggacattg gcttcactgg agatcaagta gtcatcctgc
     6001 aagatgtaaa agggaccaat tttaagtttg ccctcgtcaa tgtagcgttg gaccttgtcg
     6061 cgattttcag ggcgaatttg taagtagtca tcaaggacaa tagtttgtcc atccaagtgg
     6121 aaactcttga actcagggtc attttcaaag agatcaaaga gattgtcaaa caattccacc
     6181 aactgcatac gatggctttc aaaaggcaag taccactcac gatcccagtg actatgtgag
     6241 ataatatgta caacaacatt ttccatgaag taaaacctca ttctaaattt aaattttaac
     6301 gttttaaatg taaacttgtg attctgataa gaatcggttg agctaaagcg agccccttag
     6361 cggatatcca agtaatccaa gaccaactca cagaacatca tgttagccca ggagaaccat
     6421 tcacgagagt agagggtcgg atcatctacg tggaagcttt cgtgcatgac acctgtacca
     6481 ccatcgcagg caaccagctg atccagcaag aattttttct ctgccttatc tcttgttgtc
     6541 aatccttgga tagaaagggc gattggccag atatagcgat agaaggtatg agaacttccg
     6601 agaccgctag cgtattctcc ttggtagaag tatggatttt cagagctcag aatggtacgg
     6661 cgagtggctt gatacacttc atcatcgatc gaacagtagc ccagataggg cgcagctagt
     6721 agacttggta catttggatc atccatgatg ctggcatttc ctaggccatc tacttcaaaa
     6781 gcgtaaatct tttcgccctt gctgttggtg gtgtaagcgt agttttcgat tccttcttgg
     6841 atttcatcct gaagacgctt ggcatcagca ataacactct ggctatcagc taggtttaat
     6901 gctgcgaaga tttcttgcac ataacccaag actactacag caaacatatt tgacggaatc
     6961 aagtaactat actggcaaca gtcatcactc ggacgaaaag ctgaccaagt catacctgtc
     7021 actgcaaagt caggtccaaa gccatcattt accaaggtgt cttccttacg gtccgtatct
     7081 cggacaaaac gataaggaga gttcttgtgg tcttgttcaa ctgtccatag atggagaatt
     7141 tccttagtcg ctgcgacaaa agtttcatca aactgactag tctcgccagt ctctttccag
     7201 aggagataag ccaactgcaa aggatagcaa agcgaatcca cctcatactt gcgctcccag
     7261 atccagccgt taaggtctgt gtggtcagtc tcgtggtgcc ctttccagtt ctcctcaatg
     7321 ttgaaggagt tagcataggg atccttgagt accaaggtca tctgacgttt gaccaaacct
     7381 gcaatggtct gacgcaggag ggcatctctt ttagctacat gaaggtaggg tctgagttgg
     7441 gctgtcgaat ctcgaagcca catggcagga atatccccag tcaagacaaa agttgaacca
     7501 tcttctaaga tttcaaccgt attgtccaag gtatcggtgt agcaacgctc aaagacatca
     7561 acccactctg gatggtcctt ggcccgctct gctacttcat ctagccattc tctaacaatt
     7621 tctttcgaat aaatcatcgt gcaattccct ctttcaaaca agtttcatgt tcagtatata
     7681 gcttttgaga cagaaaatac atacacaaat gatagtcatt tttctacaaa atagttatct
     7741 ttaaaactcc ttttctaaag gccctctttt tctgatataa tgtagaaaaa cagctaaagg
     7801 aaagactatg aaaccactac ttgaaaccat cgatacccgc tttggtactg ctagcaagca
     7861 tgccttctct cggggaaata ccctgccata cacaggcgtg ccttttggga tgaattactt
     7921 tgtgccccag accagtgacc aggatggatc ttggtttttt gatccgcatc tgcctatctt
     7981 tcaggggatt cgattaactc accagcccag tccttggatt ggggactact cttggctcct
     8041 tctgacacct gtcaccagtc aactgggggg agacagcctc tttcaccgcc agtcttctta
     8101 tgatatagat aaagcttgct tccagcctca ctatttgaag ctcttttctc tgcgttatca
     8161 gattgaaacc cagctcacac cgacttgcta tggtgcttct attcgtttga atcaaaagca
     8221 aggcaaagcc ctctccctct atcttcacgc agcagatgaa ctgacagtag agcaagtaga
     8281 taagcggact cttgccctgc gacaagaagg taaaactgaa actaacaaaa attcgctaac
     8341 gatgttcact gccctgcaaa tgaacacgga tattcttgct atcagccaag aagctgggga
     8401 ctggcgaatt gacttagcaa gtagtcaaac cgagatgcaa ctagccactt ctttcatctc
     8461 tccttctcaa gctctaatca atctacctca agaagatttt gatagctgta aaacaagtgc
     8521 ccaagcggat tgggaaaatc tcctccatcg ttttgacatt atagagacag gagaggctga
     8581 ccgaaccttc tttgaccact gcctctacag actcttcctc ttcccacaga ctttttatga
     8641 ggttgatgag tcagggaaag ccatccacat ggatctggct actggtactg tcaagcctgg
     8701 tgtcctcttt agcaacaatg gtttctggga taccttccgc accaccttcc ccctctttgc
     8761 ccttatcata ccggagcact atcaacgctt tttagaaggt ttcctcaata gctaccgcga
     8821 tactggtttc cttccaaaat ggctggctcc agatgaacgg ggtatgatgc caggtacact
     8881 gctagatggc attatcgcag atagcgcctg taaggacatg gcccccgacc tagaaggaga
     8941 actcttccaa gccatgctcg aaacagccag caaagccgac cctctcggca tcaatggccg
     9001 ccacggacta gcccaatacc aagaactagg ttacctctct accgaccacc acgaaagtgt
     9061 tagccatact ctagactatg cctatagtga cttttgtatc gccagctgtg ccaaaaaact
     9121 agagaacata gaaatcgctg aaacctacaa ggctgcttca caaaattacc gccagctatt
     9181 tgacgctgag acaggttaca tgcgagcacg agacaatcaa ggaaactttc accctgactt
     9241 ctctccttat agttgggggc gagactacgc tgaatgctct gccattcaag ctactttagg
     9301 cgttctccac gacatccctg gcttaatcca actgatgggt ggaaaagaaa cctttagcaa
     9361 ctatcttttg aaagcctgtc aagatgctcc cctctttgaa acaacaggct atggttacga
     9421 aattcacgaa atgagcgaga tggctactgc tccttttgga caaatagcca tttccaacca
     9481 gcctagtttc cacattcctt atctcttccg ctacagcgat taccctgact acactgccct
     9541 tcttatcaag acgctccgtc agaaagcttt tcacccaagt tgggaagcct atcctggaga
     9601 tgaagacaat ggtagtctct ctgcttggta catctggtca gctctcggat tttatccaac
     9661 ctgtccagga aaaccaagct atgatctcgg aatccctctc tttgaccatc tacgagtcta
     9721 cctagctaaa gaaaataaat ggctagatat tcatactgag caaaaccaca gccattttaa
     9781 ctttgtcaaa gaatgccgac tggacaaaac actcgtatca actattcaac accaagacct
     9841 cctaaaagct gaacaactaa ctttcaccct cagctggcta ccaaatcact aataaccaaa
     9901 agaacctttg catcgcgcaa aggttcttct tttatgaaac ttggacttga agttgatcca
     9961 caagctgacc atccaccgtt aggttcagat agaaatccaa ggttttatct cctgcgaaat
    10021 acaaggttgg tagcgtcagc cttttttcag tctcaccagc ttgaaacgca aggacataaa
    10081 tctcgtcctg ataggcgaca ccatggacac ctgtccccgg ttgaatcgaa atcttagcct
    10141 ctaaagagga gctactttca ctacgttcaa tcctaaaatg aagagtctct ccctttgcca
    10201 cagctaggct tttttctgca aatgctagtt cctgaacaac ttcttttttt gataacccag
    10261 gagttttata aagggaaatc ttggtcaata cagggataga ttgtgcctcg gtaatcatca
    10321 cgcgcacctt ttgtgcctct actagcggac ctcgcaagag gcgcttatga ccaactgtga
    10381 agcccctgcc aaactcctgc cagacaccat ccacctctac ttgcacatga aaagcagcga
    10441 ttcgttgccc tagcttcaaa tcttctctta actcaattac atcaaaagtt ttaggagaac
    10501 ctaaatcgag ttctaactgg atgggcaagt ctgcatcgct tgcccaagag ctggtctcaa
    10561 ggccgtctgt caaatggcga caatcaaagt ctgcggaaag agctggacca gatacctcag
    10621 ctcccagagc caaatcttct ttatagagct cattgcgata ggtcgcaaat tcataaagtc
    10681 gttcaatatc ctttgcatca aagagcccag cttgattcgg cggaatatta agcaagagtg
    10741 gagttcctcg ccctactgag tgaaagtaga tttcgaccaa ctcctcgaga gacttaggat
    10801 cctgatcctc atggtagaac cagcctggac ggatggaaac atctgcctct ccgattgaaa
    10861 aaatcgtgcc cgagggatcc ccgtgctgaa gatagttcag ctctgcttct gttcctagtt
    10921 tatcaagatt caccttttgc cacagtggat cacctgcata ccctcgttca ttgccaatcc
    10981 agcggatact ggtgccttct gttgaaaaaa tcaagcaatc gccctgcagg tcacgaatgg
    11041 tttcaaacca tttttcaaat tcataattaa ccttttgcgc gccctctcct ctggcaccat
    11101 ccatccaaac ctcagcgaac ttaccagcat tcccatagtt aggatttgat aagatttcct
    11161 tcaactgagc cagataatag gcattgtagt ccgcttctcg gtccacatga tagaggggac
    11221 tatgggcatc ccacggtgac aggtagaccc ccatatccat atcaaactct gtggcagctt
    11281 gggatacttc aaggagcaag tcgccctttc ctctcctcca aggactgacc ttaaccgaat
    11341 aatctgtgtg agctgtcgga taaaggacaa agccatcgtg gtgcttgacc accaaaatca
    11401 actttttgaa gcccgtttcc ttgagcacac gaacccactc acgcgcatcc aactgactcg
    11461 ggttaaagcg ctcaggatcc tcctgtccag tcccccattc ttggtcataa aaggtattag
    11521 gaccgaagtg gataaaagct gctagttcat ctcccagata agctagctga gtctgacttg
    11581 gtaacggtcc atgcggtttg attttcttca tcgttatata tctccttctt ttgcaacttc
    11641 tcttgttcac aaggttatcc acaggttgtg gataataaac catgatctaa cagccagctc
    11701 tttccaactc caactggtag gctcaggatt tttctcctca atgttccctc ttcaaacagc
    11761 tctgtcatat ggttctgcta acacctctca gaatgctact ctccataatt attctcaggc
    11821 ttctttcagg tcattgtgtg aagaccattc actctccaga cttttccaca gattgtgaat
    11881 aagtgattat tctaagctat cacctcgtcg actataacaa aaaataaaaa gagggtcaat
    11941 aagataatta tctcttccta aatactcaga aaagattcta taatttgtac aattgaacaa
    12001 gaaatgcttc tccaaaatct atcttcaaaa gaatgttgca tctttttatc ctttcacaca
    12061 aacatttctc tttatacaga tccaagtgat aaccagatga taattggaca ctttttggtc
    12121 atttgtatat tttttgaaaa attttttaaa aaaattttat atccttttta tagaagttta
    12181 tgcatttgta tctatgtatt ctatcctatg ttatgtataa taacataaaa ttgtgctaaa
    12241 catcataatt tatattattt tccgagaaat tatagccatt gacattacct aggaattgcg
    12301 ttataacata catgtaagcg gtacccaaaa tggtgccaag tcaaaatttt taaggaggaa
    12361 aatacatgtc ttctcatcca attcaggtct tctcagaaat tgggaaactg aaaaaagtta
    12421 tgttgcaccg tccaggcaag gagttagaaa acttgttgcc ggactatctt gaaaggcttc
    12481 tttttgatga tattcctttc ttggaagatg ctcaaaaaga acatgatgca tttgcccaag
    12541 ctcttcgcga tgaaggaatt gaggttctct acctagaaca actcgctgct gaatcattga
    12601 cctctccaga aatccgcgat caatttatcg aggaatactt agacgaagcc aacatccgtg
    12661 atcgtcaaac caaggttgct attcgtgaat tacttcacgg catcaaggac aaccaagaat
    12721 tggttgaaaa aacaatggct gggattcaaa aagttgaatt gccagaaatt cctgacgaag
    12781 ctaaagatct aactgactta gttgaatcag attatccatt tgcaattgac ccgatgccaa
    12841 acctctattt cactcgcgac ccatttgcaa caattggaaa cgccgtatcg cttaaccaca
    12901 tgtttgcaga tactcgtaac cgtgaaacac tctacggtaa gtatatcttc aaataccacc
    12961 caatctatgg cggaaaagtg gatttggtct acaaccgtga agaagatacg cgtatcgaag
    13021 gtggagacga gctaattctt tctaaagacg tccttgcagt aggtatctct caacgtacag
    13081 acgcagcttc tatcgaaaaa cttttggtca acatcttcaa gaaaaatgtt ggcttcaaga
    13141 aagttttggc ctttgaattt gctaacaacc gtaaattcat gcacttggat actgtcttca
    13201 ctatggtaga ctatgacaag ttcactattc acccagaaat cgaaggcaac cttcacgttt
    13261 actcagttac ttacgaaaac gaaaaactta aaattgttga agagaaaggt gacttagctg
    13321 aacttcttgc tcaaaacctt ggtgtagaaa aagttcattt gattcgttgc ggtggtggca
    13381 atatcgtagc agctgcgcgt gaacaatgga acgacggttc taacactttg accatcgcac
    13441 ctggtgtggt agttgtttat gaccgcaata ccgtgaccaa taagattttg gaagaatacg
    13501 ggcttcgctt gattaagatt cgcggaagtg aattggttcg gggccgtggt ggacctcgtt
    13561 gtatgtctat gccatttgaa cgtgaagaag tgtaatcgct gttcggtatt cgtcaataga
    13621 aaatgtaaaa aatagaaaga ggaaataata aaatgacaaa ttcagtattc caaggacgca
    13681 gcttcttagc agaaaaagac tttacccgtg cagagttaga ataccttatt ggtctttcag
    13741 ctcacttgaa agatttgaaa aaacgcaata ttcaacacca ctaccttgct ggcaagaata
    13801 tcgctctcct atttgaaaaa acatctactc gtactcgtgc agcctttaca actgcggcta
    13861 tcgaccttgg tgctcaccca gaatacctcg gagcaaatga tattcagttg ggtaaaaaag
    13921 aatctactga agatactgct aaagtattgg gacgtatgtt tgacgggatt gaattccgcg
    13981 gattcagcca acgtatggtt gaagaattgg cagaattctc aggcgttcca gtatggaacg
    14041 gtctaactga cgaatggcac ccaactcaaa tgctcgctga ctacttgact gttcaagaaa
    14101 acttcggtcg cttggaaggc ttgacattgg tatactgtgg tgatggacgt aacaacgttg
    14161 ccaacagctt gctcgtaaca ggtgctatcc ttggtgtcaa tgttcacatc ttctcaccaa
    14221 aagaactctt cccagaaaaa gaaatcgttg aattggcaga aggatttgct aaagaaagtg
    14281 gcgcacatgt tctcatcact gaagatgctg atgaagcagt taaagatgca gacgttcttt
    14341 acacagacgt ttgggtatca atgggtgaag aagacaaatt cgcagaacgt gtagctcttc
    14401 ttaaacctta ccaagtcaat atggacttag ttaaaaaagc aggcaatgaa aacttgatct
    14461 tcctacactg cttgccagca ttccacgata ctcacactgt ttatggtaaa gacgttgctg
    14521 aaaaatttgg tgtagaagaa atggaagtaa cagacgaagt cttccgcagc aagtacgctc
    14581 gccacttcga tcaagcagaa aaccgtatgc acactatcaa agctgttatg gctgctacac
    14641 ttggtaacct ttatattcct aaagtataat tttagataat aaaccgtcta ccaacagcta
    14701 tgagggctgc gactaatagc tttagtccgg tcctctttta tgtaatggta atctattatt
    14761 tcttataaaa tatgtgaaaa atcattaaat tgaaatctaa acgcattcta ttgagtgtga
    14821 taaaggagaa tttatggcaa atcgtaaaat tgtagtagct ttgggaggaa atgcgattct
    14881 ttcttctgac ccatcagcaa aggctcaaca agaagcttta gttgaaacag ctaagcatct
    14941 tgtaaaattg attaaaaatg gagatgattt gattatcact cacggtaatg gacctcaagt
    15001 tgggaatctc ttgctccaac atttggcatc agactctgaa aagaaccctg ccttcccact
    15061 cgactcactt gtcgctatga cagaaggtag catcggtttc tggttgaaaa atgctttgca
    15121 aaatgctctc ttggatgaag gcatcgaaaa aaatgttgcc tctgttgtaa cgcaagttat
    15181 cgtagataaa aatgatccag cttttgttaa cttgagtaaa ccaatcggtc ctttctattc
    15241 agaagaagaa gcaaaagcag aagccgaaaa gagcggagcg actttcaagg aagatgctgg
    15301 ccgtggctgg cgtaaggtcg ttgcctcacc aaaacctgtt gacatcaaag aaattgaaac
    15361 catccgtact cttttaaata atggtcaagt cgtcgtagct gcaggtggtg gcggtattcc
    15421 cgtcgtcaaa gaaaacaatg gacatttgac tggtgtcgaa gcggttattg ataaagactt
    15481 cgcttcccaa cgtttggcag aattggttga tgcagacctc ttcatcgttt tgacaggtgt
    15541 agattatgta tttgttaact acaacaagcc aaaccaggaa aaattggaac atgtgaatgt
    15601 tgcccagctg gaagaatata tcaaacaaga tcagtttgca ccaggtagca tgcttccaaa
    15661 agtagaagca gctatcgctt ttgtcaatgg tcgtccagaa ggaaaagcag ttattacttc
    15721 ccttgaaaat ctaggcgcct tgattgaatc tgaaagcgga acaattattg aaaaaggata
    15781 agttgtttta ctaataagat gtattctatt tctagtatct ttatatcaaa ttagaaatta
    15841 ttcttgaaaa catgtacaat atttcaaaag atactagttt tagactttaa tatggtaaaa
    15901 caaatataaa tagaaagcgt tttcttgaat gtttatttaa gaaagtagtt ggttttttac
    15961 actttgttag acatcaggag gaaaaacaaa tgagtgaaaa agctaaaaaa gggtttaaga
    16021 tgccttcatc ttacaccgta ttattgataa tcattgctat tatggccgtg ctaacttggt
    16081 ttatccctgc gggggccttt atagaaggta tttacgaggc tcagcctcaa aatccacaag
    16141 ggatttggga tgtcctcatg gcaccgattc gggctatgct aggtactcat ccagaggaag
    16201 gttcgctcat taaagaaacg agcgcagcga ttgatgtagc cttcttcatc cttatggttg
    16261 gtggtttcct tggcattgtc aacaaaactg gtgctcttga cgtagggatt gcctctatcg
    16321 tgaagaagta taagggccgc gaaaaaatgt taattttggt attgatgcct ttgtttgccc
    16381 tcggtggtac aacttatggt atgggtgaag aaacaatggc cttctatcca ctccttgtgc
    16441 cagttatgat ggccgttggt tttgatagcc tgactggtgt tgcaattatt ttgctcggtt
    16501 ctcaaatcgg ctgtttggca tctactctga atccatttgc gacaggtatt gcttcagcga
    16561 ctgcgggagt tggtacaggg gacggtatcg tacttcgtct gatcttctgg gttaccttga
    16621 ctgctcttag tacttggttt gtttaccgtt atgcggataa gattcaaaaa gatccgacta
    16681 agtcactggt ttatagtact cgcaaagaag atttgaaaca ctttaacgta gaagaatctt
    16741 catctgtaga atctacactt agcagcaaac aaaaatcagt tctcttctta tttgtgttga
    16801 cattcatctt gatggtattg agcttcattc catggacaga ccttggcgtt accatttttg
    16861 atgactttaa tacttggttg actggtcttc cagttattgg taatattgtc ggttcatcta
    16921 cttctgcact aggtacttgg tacttcccag aaggcgcaat gctctttgcc tttatgggta
    16981 tcctgattgg tgttatttat ggtcttaaag aagataagat tatctcttcc ttcatgaatg
    17041 gtgctgctga cttgctcagt gttgccttga tcgtagcgat tgctcgtggt attcaagtta
    17101 tcatgaacga cggtatgatt accgatacaa tcctcaactg gggtaaagaa ggcttgagcg
    17161 gtctatcttc acaagtcttt atcgttgtaa cttatatctt ctatctacct atgtcattct
    17221 tgatcccatc ttcatctggt cttgccagcg caactatggg tatcatggct ccacttggag
    17281 aatttgtaaa tgtccgtcct agcttgatta tcactgctta ccaatctgct tcaggtgtct
    17341 tgaacttgat tgcaccaaca tctggtattg tgatgggagc tcttgcactt ggacgtatca
    17401 acattggtac ttggtggaaa ttcatgggca aactcgtagt cgctattatt gtagtgacca
    17461 tcgcccttct tctccttgga accttccttc cattcctata aaatagtgag tgaggtgatt
    17521 ccatgaaaat agatataaca aatcaagtta aagatgaatt tcttatatca ttaaaaacct
    17581 tgatttccta tccttcagta ctcaatgaag gagaaaatgg aacacctttt ggacaagcaa
    17641 tccaagatgt cctagaaaaa actttagaga tttgtcgaga cataggtttc actacctatc
    17701 ttgaccctaa aggttattac ggatatgcag aaatcggtca gggagcagag cttctggcca
    17761 ttctctgtca tttggatgtt gttccatcag gtgatgaagc agattggcag acaccgccat
    17821 ttgaagcaac tatcaaagac ggctgggtat tcggacgtgg tgtccaagat gataaaggcc
    17881 cttcgctcgc agctctctat gcagtaaaaa gcttgctgga ccaaggtatt cagttcaaaa
    17941 agcgcgtacg ctttatcttt ggtaccgatg aggaaaccct ctggcgctgc atggcacgct
    18001 acaataccat cgaagaacag gccagtatgg gctttgcacc tgactcatct tttcctctga
    18061 cctatgctga aaaagggctt ctacaggtca aacttcatgg ccctggatcg gatcaactag
    18121 agcttgaagt aggaggcgcc tttaacgttg taccagacaa ggccaactac caaggtcccc
    18181 tctatgaaca ggtttgtaac ggtctcaaag aagctggtta tgattaccaa tccactgaac
    18241 aaaccgtaac ggttctcgga gtgccaaagc atgctaagga tgctagtcaa ggtatcaatg
    18301 ctgtcatccg actagctacc attcttgctc ctctccaaga acaccctgct ctcagttttc
    18361 ttgcaacaca agcaggtcaa gacggcacag gaagacaaat ctttggtgat atagcagatg
    18421 aaccttctgg tcacctatcc tttaatgtcg caggtctcat gatcaatcat gaacgttctg
    18481 aaatccgtat tgacattcgg actcctgtct tagctgacaa ggaagaacta gtagagttgc
    18541 ttacaagatg tgcacaaaac taccaactcc gctacgaaga gtttgactat ctagcgcctc
    18601 tatacgtcgc agaagacagt aaactcgtta gcacactgat gcaaatctac caagaaaaga
    18661 ctggcgataa cagtcctgct atttcatccg gtggtgccac ttttgctcgc accatgccaa
    18721 attgtgtagc cttcggcgcc ttattcccag gagcgaagca gacagaacat caggcaaatg
    18781 aatgtgccgt tctagaagat ttgtaccgtg ctatggatat ttatgccgaa gccgtctatc
    18841 gacttgcaac ttaatcaggc aactgtttct accaaaaaaa atcgaccgat taatgaactg
    18901 caccccaaaa gttagacaga ataaatctaa cttttggggt gttttattat gaaattgagt
    18961 tatgaagata aagttcagat ctatgaacta agaaagcaag gacaaagctt caaacagctt
    19021 tcaaaaagat ttggtgtgga tgtttctggt ctaaagtcat ctgaatcttt gagatgagct
    19081 ttataaatcg cttttttcag tttttgcact ggtgtttcga taaactcaaa ctttttagcc
    19141 gtggtattgc ctgattttat agtatattga aactagaata gtacacctct acttctaaaa
    19201 catttttaga aatcgatttg actgtcctga acgatttgtc ctgttcttat ttcattttac
    19261 tatatttgag ccacttcgtc tttaacggct ttattcataa gctcttgtaa tttttcttta
    19321 ctatcaatta cttctgattt tccgttgtaa tttattgtaa taggttttaa cttacctaat
    19381 ttctcgacac gctcattaat ttgatctttt ttgaaggctg catatgtttt tcctaagatt
    19441 ttttcgaaaa tatatttatc agatagcggt ttgccttctt cttcagcttg gtttttgtat
    19501 tgatttgaaa cataaggaac aaatccttca tagtaaccta atgctcccat aagttcaaaa
    19561 gcttgttttc taattcaaac cattgcaact cagatttcag cttttcagat aaatcctgct
    19621 catccaaata atgacttgaa attagtgctg aactcgtttc tgtatcctgt acaggctgat
    19681 cacccatacc agcaaaaaat aaactcgttc ctagcaagac cgaacaagct cctattgcat
    19741 atttcctcaa agaaaaacgc tgctttctct caaattgaaa ttctttcatc ccatctccca
    19801 tcattcatta ttactgtata ttttgtatat cagaaatagt ttgtattcac aaatctttct
    19861 agttattccc ttatcattcc taattaaggg aggtaacata caataatttt tagttaaatg
    19921 tatatctatg ttttttgttt ttcttaataa acgcaataca aaaagagcct gttgccaagc
    19981 tctttgtact caatgaaaat caaatagcaa actaggaaac tagccacagg ttgctcaaaa
    20041 caccgttttg aggtagtaga taagactgac gaagtcagct caaaacactg ttttgaggtt
    20101 gcagatagaa ctgacaaagt cagtaacatc tatacggcaa ggcgacgctg acgtggtttg
    20161 aagagatttt cgaagagtat tagtctatta tttcttctca gcgcgaaggg ctgacaagat
    20221 ttgtgttcgg atatcatcca caccatttgg cgtatttggt aaaaagatgg tttgatttcc
    20281 tttagaggca aaggtattca aggtatccaa atactggttg gtcaagagga tagacatgat
    20341 ttgttcttct gtcatgccaa cattggcttc cttgagttcg gtgatagact ctgccaatcc
    20401 atccacaatc gccttacgtt gttgggcaat ccccacacca tgaaggcggt ctttttctgc
    20461 ttctgcttca gctgcagtga caattttaat cttgtcagct tccgccaatt cttgtgctgc
    20521 gacccgctta cgttgcgccg cattgatttc attcatggat tgcttaactt ctgcatccgg
    20581 ttcgactttg gtaatcaagg ttttcacgat aatgtagccg taagtggtca tttcttctgc
    20641 tacttggtgt tgaacttcaa gggcaatctc atcttttttc tcaaacaatt catccaaggt
    20701 taattttgga acagaagagc gaagagcatc ttcgatataa gatttaatct gagattctgg
    20761 acgtatgagt ttatagtaag catctgtcac gctctgctcg ttgacacggt actgagtcgc
    20821 tacattcatc ataacgaaca cattgtcctt ggtcttagtc tcaaccacaa tatcactttg
    20881 caacaagcgc aactgaatcc gtgctgcaat cgagtcaatc ccaaaaggca agcgaatatg
    20941 aataccgcta ttagcaacct tttggtattt cccaaagcgt tcaataatcg ccaccgactg
    21001 ctgacgaacc acataaactg tactcagtgt gactatcacc aataggagca cacaaacaat
    21061 cagaaaaatc atgaaaaata ttgccataat ggaacctcca caagtatttt tctagtatta
    21121 tagcacattt aaagaaggct gtgccgtttt tactgcgatt tttcctgaaa tgtcaataat
    21181 tagaggtgaa ttgtcctatt gtcgtccaat ctcttgctaa aataactctt tataaaaggc
    21241 aatcgtttct tctaaggttg gcataaatgg atttcctggt gcgcaggcat caatcaaggc
    21301 attcttagaa aggtattcaa agtcgaaatc tttttcttca ataccaagtt cagtcagttt
    21361 cttaggaata cctactgtct cagaaagctt ctcaatctca acaatcgcat aatcggcaca
    21421 ttcttgatct gatttacctt ctacatgaag tcccaaggct ttggcaacat tgcggaaagc
    21481 ttctggtaca cgtttagcat tttcatgttc tataactggt agcaacatgg cacagcaaac
    21541 accatgtggc aaattatata ctgcaccgag ttggtgagcc attgagtgaa cataaccaag
    21601 accagcatta ttaaagctca taccaccaag gaagatggca ttgaccatac cttcacgcgc
    21661 ttcaatatca tgtccatttt ctacagcacg aggaagatat tccttgataa gctcaatagc
    21721 accaatagac agtttcttgg ttacatcata agcaccaggt gttaccaaag cttcaacagc
    21781 gtgagtcaga gcatccatac cagtagcagc agtcaaggct tgaggtttgg aaagcatgag
    21841 ttcagggtca ttgacagaaa tcaaggcaag gctattcttg tcaaccatta ccatcttaac
    21901 cttgcgttct tcatcagtaa tcacatagtt aatagtgatt tctgctgatg tacctgccgt
    21961 tgtattgata gccacaaccg gcaagccttt tttagcagac ttatgaagcc cttcataatc
    22021 ctgtggtttt ccaccatttg tagccatgat agaaatacaa ctagctgcat cctgtggaga
    22081 acccccgcca agactgatga taaaatcaca tctatgttct tgcaaagcag ctaccccatc
    22141 tgtgacattt ttacaagtag ggtttggctc tacatcgcta aagatgacat attcgattcc
    22201 ttctgtatcc agtggtttta aagtcttagg taaaatatca ctgccttcga tgtacttatc
    22261 tgtcaccaaa agtgcctttt tatagccaag ttccttgata taaggaccca cttcatttac
    22321 aacacctttt ccaataaggt tgactgccgg aacataaaat atagccatat aattttcctc
    22381 ctgcgcctcc gcgctatcta tttaacatca ttatattact ttttgtattc gttttcaatt
    22441 atttgtgaat tgtttaacaa atctttttaa aaggatagga gggacgtaag ttcacctcct
    22501 atataaacaa gttttattta tgtagtggtc ccaacaactg acatgcacga tagtctgctg
    22561 attctagatc ttctgttcca aataaggacc aatttttagg tctaaagata tcttcctcag
    22621 gtacattatg catattgaca ggaattctca acatagaagc caaggtaatc aagtctgctc
    22681 caatgtgtcc atatgttatg gctccgtgat tagctcccca attattcatg acgtcataga
    22741 cagacttgaa agcacctttt cctgtcaaac gtggagcaaa ccaagtagtt ggccatcctg
    22801 aatctgtacg attatctaaa gtatggtgaa catcttcagg aagttcaagt gtgtaacctt
    22861 ctgcaatttg tagcactgga ccaacccctt ttagaagatt gagacgtacc attgttactg
    22921 gcatatcccc cttcgtcaag aaacgagttg agaatcctcc tccacggaag tactcgcggt
    22981 ttgctggtgg gaagtctgta ttttcaagca tagcctgtac ttcactttct tccaactccc
    23041 agaatggttt cataacaggt ttgccatctc gagtagcttg acctgtacca tccaatgtac
    23101 aagaaccaga gttgattaga tgtaagaagc cagctgcagc acaaccctct aaagtatgtc
    23161 ccgttacacg tttaacagcc tctggactcc aataagtgcg cacatcagca aagatttgtg
    23221 gagtatttgt taatagataa ttaaagagca tagacacacc atttagtgaa tcattctctg
    23281 tcgcaaatac aaatggtttt cgaataccat tccagtcaaa ctgagtattg aggaaagttt
    23341 ccataaaatc tccatttgga aaatggtctg tccactgacg ttgaccttgg aaaccagcta
    23401 ctaaagcatg gtgaccaacc gcttcttcct caaaaccaag ttcagcaagc cttgggttac
    23461 caaccattaa gtcacgtcca atcatgaaca tcttaataac aaattcccat tgtttttctt
    23521 tctcttcttt agaaagaatc aaatcctcac gatttcggtc aaccccttct ttgatatgtt
    23581 cttttaccca aaccatagca cgttcgaact cttctgggtc ataaatacca cggtccatac
    23641 ggcgcgtgaa ctccgtcata tctaccgatt catttcgcat tcctaagtat tcttggaaga
    23701 aatctggatt tacaatagaa ccgccaatcc ccatcgaaac actacccatt gataggtaag
    23761 cagtgtctct catcaagcca gttgcaagag ctgcacgcgc ataacgtaaa agtttttctt
    23821 tgacatcttc tggaatatct gtatcattag cttcctgaac atctctacca taaatcccaa
    23881 aggctggaat ccctttttga gcatgtgaag ctagtacagc tgcaagatag acagctcctg
    23941 ggcgttctgt cccattaaat ccccaaatag catgaggaat atctggagac atatccatag
    24001 tttcactacc ataacaccag catggtgtaa ctgtaattgt tgcgcaaaca tttgattttt
    24061 taaacaactc atgggaagct gcagcctctg gaacacgacc aatggtagat ggagaaatca
    24121 cacattccac aggttcccca tctggatatt tcaatgtgct tgaaatcaaa tctgccacac
    24181 ttttagccat gttcattgtt tgtacttcaa gtgattcgcg tacaccttga cgacgaccat
    24241 caatagtcgg acgaatccca atacgtggat gttgaatcat actattttcc tcttattttt
    24301 ctgtttcttt catactaccg atgataattt ttaaaattac ttataagtat aaacctctac
    24361 ctctgccaaa cttaaaggaa ttcctgcgtt tctcaaagaa attctaacct tttttccctt
    24421 cagccctttt aagtctatgg atagattatt gctttctaaa ctgtcaatat gttgtttaaa
    24481 aacttcatga ttatttgaat catatataat aatatcaaaa tttgataatc tctgaatttc
    24541 agcatctgtt ctattataaa taattaactt ttctaattct tcggtttgtg ctaaatctat
    24601 ctcccaccat gaaggagaat ctcctttggt atgagtcact gaatgatgac cataatctcc
    24661 gtttttattt ccatcaactg ctagacgaga aaaaccattg taatccgttg aactctgtcg
    24721 agtttctttg gttaatgcaa tattagaaag tttcttcgga gttctctttg aaccataggc
    24781 ttcaacttcc gctaaactta acggaatagc tgctgatttt aattctattt tgactagctt
    24841 agcccctaca gaaggtactt ttaaagataa caaaccatca actactttat caaaatgtct
    24901 tctaaaaact tcttctcctg atgaagatag aaaaataaca tcaaaattag ataaacgctg
    24961 aggttcggca tctgttctat tataaatatc aactttagaa accgtaaact cttctcccag
    25021 atcgacctgc caccaagcgt tagaatctgc cttagtatga gtcaccgaat gatgtccgta
    25081 atctccatct ttattaccat caactgctaa agcagctaca ccctcataat tggttgaact
    25141 ttgagtagct accttatttg tagagactac tttatcttct gttattttat ctatatcctc
    25201 ttcagattgc ttaccatctg attctctaaa aacctctact tctgctaaac tcaaaggcac
    25261 tccactcgtt agtaatttaa ctttaatata ccttgctcct ttttctttga aatctagact
    25321 aacagattca cccgacaaat tattaacatg tttcttagca acttcgtttc tattattgtc
    25381 atatagaatc acatcaaaat tagatagacg ttgagtctca gcatctgtgc gattataaat
    25441 tttaacaagc ccaactttat ccattttttt caaatcgact tcccaccaag agggattatc
    25501 tgccctagtg tgtgttaccg aaccagagtt aaaattacca tttctgttac catccacagc
    25561 tctattaggg tctccattgt aatctacaga actttgtgtt gttggttttg catatgctat
    25621 attcaaatta ccatcattaa atttatctgg tgttgggaaa gggactgggc ctgtcccttc
    25681 agtatttata gacatctcta ccattccatt atgattaacc gtaatggtat aaacatgggt
    25741 attctcatcc caattttctg tataagtata atgattttta tcgccactta tatttatctg
    25801 aggtttatga ccagtatgcc cttttaatgt aagtgttgtt gtcctaaagt cattatctac
    25861 aggattgatg gaataatttt tgcttatcca gttcgctaac tctaattctt ctttcttcca
    25921 actttttgat gcatcaaaat ttcctgataa tgcccacata gctgtcttat ctgtcctgta
    25981 att
//
LOCUS       DAVAZT010000030        25336 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVAZT010000030 DAVAZT010000000
VERSION     DAVAZT010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25336
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.030"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..309)
                     /locus_tag="VQT45_001161"
     CDS             complement(<1..309)
                     /locus_tag="VQT45_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter substrate-binding protein"
                     /protein_id="HET2359489.1"
                     /translation="MKKKWMYYAACSSNESADDSSSDKGDGGSLVVYSPNSEGLIGAT
                     IPAFEEKYGIKIELIQAGTGELFKKLESEKEVPVADIIFGGSYTQYATHGELFENYIS
                     K"
     gene            complement(897..1673)
                     /locus_tag="VQT45_001162"
     CDS             complement(897..1673)
                     /locus_tag="VQT45_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HET2359490.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            1795..2541
                     /locus_tag="VQT45_001163"
     CDS             1795..2541
                     /locus_tag="VQT45_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2359491.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            2554..3534
                     /locus_tag="VQT45_001164"
     CDS             2554..3534
                     /locus_tag="VQT45_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HET2359492.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            3729..4049
                     /locus_tag="VQT45_001165"
     CDS             3729..4049
                     /locus_tag="VQT45_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2359493.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            4095..4403
                     /locus_tag="VQT45_001166"
     CDS             4095..4403
                     /locus_tag="VQT45_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2359494.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            4420..5718
                     /locus_tag="VQT45_001167"
     CDS             4420..5718
                     /locus_tag="VQT45_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2359495.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASANLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQTLGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVITQLVILAMSTLVYFPFFKVQDRLAYQNEIKQS"
     gene            5869..8307
                     /locus_tag="VQT45_001168"
     CDS             5869..8307
                     /locus_tag="VQT45_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HET2359496.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMTIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            8326..8994
                     /locus_tag="VQT45_001169"
     CDS             8326..8994
                     /locus_tag="VQT45_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HET2359497.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEVGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            9012..10100
                     /locus_tag="VQT45_001170"
     CDS             9012..10100
                     /locus_tag="VQT45_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HET2359498.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            10555..13056
                     /locus_tag="VQT45_001171"
     CDS             10555..13056
                     /locus_tag="VQT45_001171"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HET2359499.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLIRSKEIVAENNGALD
                     KVYNETVKAVTEQIDSLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAATGESISYVTWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            13250..13945
                     /locus_tag="VQT45_001172"
     CDS             13250..13945
                     /locus_tag="VQT45_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2359500.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            13957..14373
                     /locus_tag="VQT45_001173"
     CDS             13957..14373
                     /locus_tag="VQT45_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2359501.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(15000..15092)
                     /locus_tag="VQT45_001174"
     CDS             complement(15000..15092)
                     /locus_tag="VQT45_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HET2359502.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            15253..16224
                     /gene="ruvB"
                     /locus_tag="VQT45_001175"
     CDS             15253..16224
                     /gene="ruvB"
                     /locus_tag="VQT45_001175"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HET2359503.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            16205..16777
                     /locus_tag="VQT45_001176"
     CDS             16205..16777
                     /locus_tag="VQT45_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HET2359504.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTAVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            17008..17766
                     /locus_tag="VQT45_001177"
     CDS             17008..17766
                     /locus_tag="VQT45_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HET2359505.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            17775..18578
                     /locus_tag="VQT45_001178"
     CDS             17775..18578
                     /locus_tag="VQT45_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HET2359506.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            18600..19859
                     /gene="rseP"
                     /locus_tag="VQT45_001179"
     CDS             18600..19859
                     /gene="rseP"
                     /locus_tag="VQT45_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HET2359507.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            19872..21725
                     /locus_tag="VQT45_001180"
     CDS             19872..21725
                     /locus_tag="VQT45_001180"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HET2359508.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            21825..23204
                     /gene="bglA"
                     /locus_tag="VQT45_001181"
     CDS             21825..23204
                     /gene="bglA"
                     /locus_tag="VQT45_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HET2359509.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNELIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIHDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KKLSDNNGF"
     gene            23396..25204
                     /gene="glmS"
                     /locus_tag="VQT45_001182"
     CDS             23396..25204
                     /gene="glmS"
                     /locus_tag="VQT45_001182"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HET2359510.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
BASE COUNT         7736 a         4313 c         5536 g         7751 t
ORIGIN      
        1 ttttgaaata tagttttcaa agagttctcc gtgggtagca tattgtgtat aagaaccacc
       61 aaagataata tcagctacag gaacttcttt ttctgactct agttttttga aaagttctcc
      121 agtaccagct tgaatcagtt ctattttgat accatatttt tcttcaaagg caggaatagt
      181 tgctccaatt aagccttctg agtttggtga ataaacgact agcgaaccac cgtctccttt
      241 atcagatgaa ctgtcatcgg cagattcatt agaagaacaa gcagcataat acatccattt
      301 ctttttcatg atggatacct ccgttgtgtt atttaagttt attttaaaac aatgtaagcg
      361 tttttaaaac ctacaattct attctatagt gtattgaatc tataacagta cacattgact
      421 gctaaaatat ttctataaat taatttgact ttcctgatag agatgttcac atcttatttc
      481 aattcactat attagagtaa aattctctac aaaaaaaaag aatagcctat tttactattt
      541 ttccgagtga tttcaattcc tttggggaaa tatggagata ctttttaaat cctgacaaat
      601 ggttgtttct ttttctaaat cggtgatact gtatcggaga atgcgcgtga ggtcacaaag
      661 gctgcgatag agcttctatg gagaatttct ttttggagag attttttaaa ggaatgagac
      721 atccgctacc tccttggaag gtttttttgt gataagtata gcagtttaaa aattctagag
      781 caaggtaaaa tagaaaaggt ttggctaaaa ttttttagct aaaccttttg aaaagttaag
      841 tatgtattat agatgcttgt tatctgcaaa tagctagagc atttcaagga aataaactag
      901 aaataacaat taatatggtg gttcagaaat accttttgat aatcaataag atcttcagga
      961 tgaagtgcgt tgattccatc catttcatat ttccgattta ataaacgata tttgttttca
     1021 ccaaattgat gaaaagggag tagttgaact tggtcgatat ttaatgagtt aaatagagta
     1081 gcgaattttt ctgcatcctc taaactattg ttaaaattag gaataactgg gattcttaaa
     1141 acgatagttt tattttgtga aaaagcataa tgaatgtttt taataatcat ttgattaaaa
     1201 accccagtca cttttttatg ttttatagaa ttataatgtt ttaggtctgt gtagataaaa
     1261 tccacatatt gaattaaatc aataaatttt tcatgatcaa caaaggcagt agtttcaatg
     1321 gcagtgtgta tgtgatgttc tttagctgat tttaagatag ctttagcaaa ttcaaactga
     1381 gcaaatattt cacctcctga taaagttaaa cctccaccgg attcttcgta aaattctttg
     1441 tcttttaata cctctgtaat aatttcttct acagtctttt cttcaccgac taaggtgaat
     1501 ttctctcgtt gagcatcttt cattttttca ggtttcattc tttgagattc aggattagaa
     1561 caccatggac agcgcagagg acatcctttt aaaaaaacag ttgtacgaat acccgggccg
     1621 tcatgaattg aaaagtgttg aatattaaaa ataattcctt tagatatttc cataagagtt
     1681 cctcctcttc ataagtctat cctatcacaa aaacgaaaga aaaacaatta cgaacgaaag
     1741 gttaatttgt tgttttttgc tttttatttt ggtagaataa aacggaggtg taaaatgaaa
     1801 agattggaac aaattattaa attagtatca gaatatgaaa agatcgacgt taatacatta
     1861 tcggaaaaat taaatgtatc gaaagtaacg attagaaaag atttagataa attagagtca
     1921 aaaggtttat tacacagaga gcatggatat gctgtattaa atagtggaga tgacttaaat
     1981 gtacgtttgt caattaatta tgaaattaag agaaaaattg ttcaggaagc agtaaaattg
     2041 gtgtcagata atgaaacgat aatgatagaa tctggatcga cctgtgcttt acttgctgag
     2101 gaaatttgca agcaaaaaag aaatgttacg attgtaacaa attcattttt tatagcaaat
     2161 tttgtgagag cttatgattc atgtcgtatt attgttcttg gtggagagtt tcagaaggat
     2221 tcacaggtta ctgtgggacc tttattaaaa gaaatgatac agacttttca tgtgcatcaa
     2281 gcttttgttg ggacagatgg atacgataaa gagatgggct ttacaggaaa agatttaatg
     2341 cgcagtgagg tagttcaata tatttcagca gcgtcggata aagtcattgt cctaactgac
     2401 tcaagtaaat ttgataaaag gggtacagta agaagatttg ctttaagtca agtctatgaa
     2461 gtaataacag acgaaaaact ttctaaacaa aatatagcta cattagaaaa tgctgggata
     2521 atggttaagg tagtttcgta agaggttaag tgtatgaatc aagataggaa taaactgctc
     2581 tctaaaattg cttatctgta ttatattgaa aacttaaatc agtcacaaat agcagcaaaa
     2641 ttaggaattt atagaacctc tattagtaga atgttaacag aagcaaggaa tgcaggaatt
     2701 gttaaaattg aaatagagaa ttttgatacc aatatgttta agttggaaaa ttatgtaaaa
     2761 gaaaaatatg gtctggaaag tttagaaatt attccaaatg aatttgatga taatccaaca
     2821 attttatctg aaagaatttc tcaagttgca gcaggtgtcc ttaggaatct aattgatgat
     2881 aatatgaaaa ttggcttttc ttgggggaaa agtttaagta atttagtaga tttaattcac
     2941 agtaaaagtg tccgaaatgt tcacttctat cctctagcag gtggtcctag tcacatacac
     3001 gctaaatacc atgtgaatac actgatttat gaaatgtcta gaaaatttca tggagagtgt
     3061 acatttatga atgcaacgat tgtgcaagaa aataaattgt tagcagatgg tattttgcaa
     3121 tcaagatatt ttgaaaattt gaaaaatagt tggaaagatt tagatatagc tgtagtcgga
     3181 attggtgatt ttagcaataa aggaaagcat caatggttag acatgcttac agaggatgac
     3241 tttaaagaat tgaccaaagt taaaactgta ggagaaattt gttgtcgatt ttttgattca
     3301 aaaggtaaag aagtctatga aaacttacag gaaagaacga tagcaatctc tttggaagat
     3361 ttaaaaaata ttcctcaaag tttagctgtt gcttacggtg atacgaaagt atcttcgatt
     3421 ctttctgtct tgcgtgctaa tttagtaaat catttgatta cagacaaaaa tacaatttta
     3481 aaagttttgg aagaagatgg ggatttgact tttagagaga ttctaggtga gtgaaaatga
     3541 tagactgatt cagtttatcg tttttctttt tagttgattg cacatttgtg cttatataaa
     3601 caaaaatagt ttatctgttg tttttggatt gacaacttta ttatgtagtt gtattctata
     3661 gttacaaaag aaaattttaa aatttcaaat gaaaaaagct ttttacatag tgaaatgagg
     3721 aggaatttat ggaaattatt gttccagatc aaattatcat gggtttaatt ttatatgctg
     3781 gtgatgcgaa acaacatatt tataaagcgt tagattacat aaaaaatggt acatgtgaac
     3841 ggtgtgaaga agaaatccag ttagctgatg ccgccttatt agaagcccat aatctacaaa
     3901 caaaattctt ggcacaagaa gcgtctggta caaagacaga aattacagct ctctttgttc
     3961 attcacaaga tcatctcatg actagtatga cggagattaa tttaatcaaa gaaattatta
     4021 gtttgagaaa agaacttcat aaaaaataat actagagtat tatcattgtt attaacatag
     4081 aggaggaaaa cataatggtg aagattggtt tgttttgtgc agcaggtttt tctactggta
     4141 tgcttgtaaa taatatgaaa attgcagcgc aatctagtgg agttgaggca gaaatagagg
     4201 cgttttctca gtctaaatta gcggattatg cgccaaatat agatgttgca ctattgggtc
     4261 cacaagttgc ttatacatta gataaatcaa aagaaatttg tgataagtgt gatgttccga
     4321 tagctgttat tccgatgatg gactatggta tgttagatgg gaaaaaagta ttagatttgg
     4381 ccctatcttt gattagtggg taagaaaagg agatttatta tgtcaaagat ggatgttcag
     4441 aaaatcattg caccgatgat gaagtttgtg aatatgcgtg gcattatagc tctaaaagat
     4501 gggatgttag caattttgcc attgacagta gttggtagtt tgttcttgat tatgggacaa
     4561 ttgccgttcg aaggattaaa taagagcatt gctagtgttt ttggagctaa ttggacagag
     4621 ccgtttatgc aagtatattc aggaactttt gctattatgg gtctaatttc ttgtttttca
     4681 attgcctatt cttatgctaa gaatagcgga gtagaggctt taccagctgg agttctatct
     4741 gtatctgcat tctttatttt gctaagatca tcttatatcc ctaaacaagg tgaggcgatt
     4801 ggggacgcta ttagtaaagt ttggtttgga ggccaaggaa ttatcggtgc tatcattata
     4861 ggtttggtag taggaagtat ttataccttc tttataaaga gaaaaattgt tattaagatg
     4921 ccagaacaag ttccacaagc tattgccaaa cagtttgaag caatgattcc agcatttgta
     4981 attttcttat cttctatgat tgtatatatt ttagcgaagt cattgactaa tggcggaaca
     5041 ttcatagaaa tgatttattc tgctattcaa gttccgttgc aaggtttaac tggatctttg
     5101 tatggtgcta ttggaattgc attctttata tcatttttgt ggtggtttgg tgttcatggg
     5161 caatcggtag taaatggagt agtgacagct ctgcttttat ctaatcttga cgctaataaa
     5221 gctatgttag cctctgctaa tctatcatta gaaaatggtg cacatattgt tactcaacaa
     5281 tttttagatt catttttaat tctatcaggt tcagggatta cgtttggtct tgtagttgcc
     5341 atgctttttg cagcaaaatc aaaacaatac caaaccttag gaaaagttgc agcttttcca
     5401 gcaatattta acgtaaatga gccagttgta tttggatttc cgattgtcat gaatccagtt
     5461 atgtttgtac ctttcattct tgttcctgta cttgcagctg tgatagtata tggagctatt
     5521 gcaacaggtt tcatgcagcc attctcaggg gtaacattgc cttggagtac accagctatt
     5581 ttatcaggat ttttggtggg tggatggcaa ggagttatta ctcagctggt gatattagcg
     5641 atgtctacat tggtttattt tccattcttt aaagtacagg atcgtttagc ttaccaaaat
     5701 gaaatcaaac aatcttagag gtatttgtgt gttactgtta aactcacaca tttgtgctaa
     5761 aaattagaga gttaaaattt ttctagttaa aagcttgaaa atttctataa aaatcggtat
     5821 tatattttcg aaagaaataa aaatattttc gaaagaaagg tggttacgat ggtaaataca
     5881 gaagtagcaa gaacaacaat caagacagaa tattttggca gccttactga aaggatgaac
     5941 aaatatcgag aagatgtttt aaataaaaaa ccttatattg atgctgagag agcagttcta
     6001 gcaacacgcg cctatgaacg atacaaggaa caacctaatg tcctaaaacg tgcatatatg
     6061 ctgaaagaaa ttttggaaaa tatgactatc tatattgaag aagaatctat gattgcggga
     6121 aatcaagctt cttccaataa agatgctcct atttttccgg aatatacgct agaatttgtt
     6181 ctcaatgagt tggatctttt tgaaaagcgt gatggagatg ttttctatat tacagaagaa
     6241 acaaaagaac aacttagaag tattgctccg ttttgggaaa ataataattt acgtgctaga
     6301 gctggtgcct tattacctga agaagtgtct gtttatatgg aaacaggatt cttcggtatg
     6361 gaaggtaaga tgaattctgg agatgctcac ctagcagtta actatcagaa acttttgcaa
     6421 tttggtttaa gaggttttga agagcgggct cgtaaagcaa aagtagctct agatttaaca
     6481 gatccagcaa gtattgataa atatcatttt tacgactcta tatttatcgt aatcgatgct
     6541 attaaagtat atgcaaagcg ctttgttgct cttgctaaaa gtttagccga aaatgcaaat
     6601 cctaaacgta agaaagaatt acttgagatt gcagatattt gctctagagt cccatatgaa
     6661 ccggcaacta cttttgcaga agctattcaa tcagtttggt ttattcaatg tattttacaa
     6721 attgaatcta atggccactc tctttcatat ggccgttttg atcaatatat gtatccatat
     6781 atgaaggctg atttagaaag tggtaaagaa acagaagata gcattgttga acgtctgaca
     6841 aatctttgga ttaagacaat tacaatcaat aaggttcgca gtcaatcaca tacattttct
     6901 tcagcaggaa gtcctttata tcaaaatgtt acaattggtg gacagactcg agataagaag
     6961 gatgctgtta acccattatc ttatttggta ttaaaatcag ttgcacaaac ccatctaccg
     7021 caacctaatc taactgtacg ttaccatgca ggtttagatg ctcgtttcat gaatgagtgt
     7081 attgaagtga tgaaacttgg ttttggtatg cctgcattta ataatgatga gattattatt
     7141 ccttctttta ttgcaaaagg agtattggaa gatgatgctt atgattacag tgccattgga
     7201 tgtgttgaaa cggcagttcc agggaaatgg ggctatcgtt gcacaggtat gagttatatg
     7261 aacttcccta aggttctact tatcacgatg aatgatggaa ttgatccggc ttcgggtaaa
     7321 cggtttgcac caagctttgg tcattttaag gatatgaaga acttttctga attagaaaat
     7381 gcttgggata aaacactaag atatttgaca cgaatgagtg ttattgttga aaattctatt
     7441 gatttatcat tggaacgaga agttcctgat attctatgtt cagcattgac tgatgattgt
     7501 attggtcgtg gaaaacacct taaagaaggt ggagcagtat atgattatat atcaggattg
     7561 caagttggaa ttgcaaattt gtcggattca ttagctgcaa ttaaaaaatt ggtgtttgag
     7621 gaagaacgta taagcccaag tcagctttgg catgcactgg aaacagatta tgccggagaa
     7681 gaaggtaagg tcattcaaga aatgttgatt catgatgcac ctaagtatgg taatgatgat
     7741 gattatgctg acaaattggt tactgctgct tatgacattt atgttgatga aattgctaaa
     7801 tatcctaata cacgttatgg aagagggcct attggaggaa ttcgttattc aggaacatct
     7861 tctatctcag ccaacgtagg gcagggacgt ggaacattag caactccaga tggacgcaac
     7921 gcgggtacac cgttagcaga gggttgttca ccatcacata atatggatca acacggccct
     7981 acatctgttt taaaatctgt ttcaaaatta ccaacagatg aaatcgtagg tggggttctc
     8041 ttaaatcaga aagtaaatcc tcaaacgtta gccaaagaag aagataaatt aaaactaatt
     8101 gctttgttac gaacattctt taatcgttta catgggtacc atattcaata caatgttgtt
     8161 tccagagaga cgttgattga cgctcagaaa catcctgaaa aacacagaga cttaattgtt
     8221 cgtgttgcag gatactctgc attcttcaat gttctttcta aggcaaccca agatgacatt
     8281 ataggacgta ctgagcatac tttgtaaaat aaagaggttc tttttatgga atttatgctt
     8341 gacacattaa atttagatga gattaaaaag tggtctgaaa ttttgccgct agctggggta
     8401 acttcaaatc ccactattgc aaaaagagag ggttctatta atttttttga acgaatcaaa
     8461 gatgtaagag aattgattgg ctctacaccc tctattcatg ttcaggtgat ttctcaagat
     8521 tttgaaggca tcttaaagga tgctcatgaa attcgaagac aagcaggaga tgatatattt
     8581 atcaaagtac ctgttactcc agctggatta cgtgcaataa aggtgctaaa aaaagagggc
     8641 taccatatca ctgcaacagc tatttataca gttattcagg gattattagc tatcgaagta
     8701 ggagcggatt acctagctcc atattataat agaatggaaa atctgaacat tgattcaaat
     8761 tctgtcattc gtcaattagc tcttgctatt gatagacaga actctcctag taagatttta
     8821 gctgcatcct ttaaaaatgt agcacaagta aataatgctt tagctgcagg tgcgcatgct
     8881 gttacagcag gagcagatgt ttttgaatca gctttcgcca tgccatctat ccaaaaggcg
     8941 gttgatgatt tttctgacga ttggtttgtt actcaaaata gtcgttccat ttagatagag
     9001 aggaaataca tatgagaatt tttgctagtc cttctagata tattcagggg gaaaatgcct
     9061 tgtttgaaaa tgccaaatca attttggatt tgggaaatta ccctattcta ttatgcgatc
     9121 agttggttta tgatattgtt ggaaaacgat ttgaagatta tctacatagg tatggtttcc
     9181 atattgttct ggcgctattt aatggtgaag cttctgacaa tgaaatcaat cgagttgttg
     9241 ccttggctga gaaagaaaat tgtgatagta ttatcggtct tggtggggga aagacgattg
     9301 atagcgcaaa agctattgca gatttgattg aaaagcctgt tattattgct ccaacaattg
     9361 catcgaccga cgcacctgta tctgctttat ctgttattta tacagatgaa ggtgcatttg
     9421 atcattatct attttattct aaaaatccag atttagtttt ggttgataca aaagttattt
     9481 cacaagcccc taagcgttta ttagcgtctg gtattgcaga tggtttagca acttgggttg
     9541 aggcgcgtgc ggttatgcag gcaaatggaa aaactatgtt gggacaacag caaacattgg
     9601 ctggagttgc aattgcgaag aaatgtgaag aaacgctgtt tgcagatggt ttacaggcta
     9661 tggcagcttg tgaagctaaa gtggtgacac cagcattaga aaatattgtt gaagctaata
     9721 ctttattgag tggcctaggt tttgaaagtg gaggattagc tgcggcgcat gcaattcata
     9781 atggttttac tgcattgaca ggtgacattc atcatttaac acatggtgaa aaagtagctt
     9841 atggaacttt agtacaacta ttattggaaa atagacctaa agaagaactt gataagtata
     9901 ttgagtttta caaaaaaatt ggtatgccaa caactctaaa agaaatgcat ttggatcaag
     9961 ttggatatga tgatttaata aaagttggta aacaagcaac tatggagggt gagacaattc
    10021 atcagatgcc gtttaagatt tcgccttcag atgttgctca agctattatc gctgtagatg
    10081 cctatgtaaa ttcaaaataa acaataagga ctactgtttt ccaaatggta gtcttttatt
    10141 gatcctcgta ttgaattcta tagcagattg aaataagatg agaacaaatc gattgggaaa
    10201 gtaaaattaa tttctataag tattttagca attgtttcgt actatttcag attcagtcca
    10261 ctatacgttc ttcataaatc aaaaagcgac ataggttgtc ggctatttat tgtgaataca
    10321 ttaattagca ttccagtttt atcttcggtc taaaataagt attttgtgct atacgagata
    10381 agtttcttga cttactcctt gatttactgc ataacaatgg gataaaaagt gggagataga
    10441 gcaattcata gtcatcaaaa ttaatgagat acagtataca gtttttcctt taaacacatt
    10501 tcaaattccc tcaaaaatgg tataatagta acatcacaaa attggagaga gaccatgagt
    10561 ttttacaatc ataaagaaat tgagcctaag tggcagggct actgggcaga acatcataca
    10621 tttaagacag gaacagatgc atcaaaacct aagttttatg cgcttgatat gttcccttat
    10681 ccgtctggag ctggtctgca cgtaggacac ccagaaggtt atactgcaac cgatatcctc
    10741 agtcgttaca aacgtgcgca aggctacaat gtccttcacc caatgggttg ggatgctttt
    10801 ggtttgcctg cagagcaata cgctatggat actggtaatg acccagcaga atttacagcg
    10861 gaaaacattg ccaacttcaa acgtcaaatc aatgcgcttg gattttctta tgactgggat
    10921 cgtgaagtca acacaacaga tccaaactac tacaagtgga ctcaatggat tttcaccaag
    10981 ctttacgaaa aaggcttggc ctatgaagct gaagtgccag taaactgggt tgaggaattg
    11041 ggaactgcca ttgccaatga agaagtgctt cctgacggaa cttctgaacg tggaggctat
    11101 ccagttgtcc gcaaaccaat gcgccaatgg atgctcaaaa tcacggctta cgcagagcgc
    11161 ttgctcaatg acttagatga actagattgg tcagagtcta tcaaggatat gcaacgcaac
    11221 tggattggta aatcaactgg tgccaatgta actttcaaag taaaaggaac agacaaggaa
    11281 tttacagtct ttactactcg tccggacaca cttttcggtg cgactttcac tgttttggct
    11341 cctgaacatg aattagtaga tgccatcaca agcacagagc aagcagaagc agtagcagac
    11401 tacaaacacc aagccagcct taagtcagac ttggctcgta ccgaccttgc caaagaaaaa
    11461 actggtgtat ggactggtgc ttatgccatc aatcctgtca atggtaagga aattccaatc
    11521 tggattgcgg attacgttct tgctagctat ggtacaggtg cggtaatggc tgtgcctgcc
    11581 cacgatcaac gtgactggga atttgccaaa caatttgacc ttccaatcgt cgaagtactt
    11641 gaaggtggaa atgttgaaga agctgcctac acagaagatg gccttcacgt taattcagac
    11701 ttcctagatg gactcaacaa agaagacgct attgccaaga ttgtggcttg gttggaagaa
    11761 aaaggctgtg gacaagagaa ggtaacctac cgtctccgcg actggctctt tagccgtcaa
    11821 cgttactggg gtgagccaat cccaatcatt cattgggaag atggaacttc aacagctgtc
    11881 cctgaaagtg aattgccact tgttttgcct gtaaccaagg atatccgtcc ctcaggtact
    11941 ggtgaaagtc cactagctaa cttgacagac tggcttgaag tgactcgtga agatggtgtc
    12001 aaaggtcgtc gtgaaacaaa tactatgcca caatgggcag gttcaagctg gtactacctc
    12061 cgctatattg acccacacaa tactgagaaa ttggctgacg aggatctgct caaacaatgg
    12121 ttgccagtag atatctacgt gggtggtgcg gaacatgctg tacttcactt gctttacgct
    12181 cgtttctggc ataaattcct ctatgacctc ggtgttgttc caactaagga accattccaa
    12241 aaactcttta accaaggaat gattttggga acaagctatc gtgaccaccg tggggctctt
    12301 gtggcgactg acaaggttga aaaacgtgat ggttctttct tccatgtgga aacaggggaa
    12361 gagttggagc aagcgccagc caagatgtct aaatcgctca agaacgttgt caacccagac
    12421 gatgtggtgg aacaatacgg tgctgatacc cttcgtgtct atgaaatgtt catgggacca
    12481 ctcgatgctt cgattgcttg gtcagaagaa ggtctggaag gaagtcgtaa gttccttgac
    12541 cgtgtttacc gtttgattag aagtaaggaa attgttgcgg aaaacaatgg cgctcttgac
    12601 aaggtttaca acgaaactgt taaagctgtc acagagcaaa ttgattccct caaattcaac
    12661 acagccattg cccaacttat ggtctttgtc aatgcggcta acaaggaaga caagctctat
    12721 gttgactatg ccaaaggatt tatccaattg attgccccat ttgcacctca cttggcagaa
    12781 gaactctggc aaactgttgc tgcaacaggt gagtcaatct cttacgtgac ttggccaaca
    12841 tgggacgaaa gtaaactggt tgaagacgaa atcgaaatcg ttgtccaaat caaaggtaaa
    12901 gtccgtgcca aactcatggt cgctaaagac ctatcacgtg aagaattgca agaaattgct
    12961 ctagcggatg aaaaagtcaa agcagaaatt gacggtaagg aaatcgtgaa agtgattagt
    13021 gtaccaaata aattggttaa tattgttgta aaataaccaa tttatttgct gatttccaac
    13081 ctcaaacagt ttcccaaact gtttgagcca actaaactcg ttaatatcgt tgtgaaataa
    13141 ggtaggaatc cttcagagta gaatctggag gattttttga atcttcttat gaaagtatgg
    13201 tatactatgg gcaactataa agtttgaaaa gtgaaaaaag gagaaagcta tgccagtaaa
    13261 tgaatatggt caaatgattg gggagtcaat ggaaggttat acaccaggtg aactgccttc
    13321 tattgatttc ttagaagggc gttatgctag gatagaggct ctttcagtgg aaaagcatgc
    13381 ggaggatttg ctagctgttt atgggcctga tacgcctcag gagatgtgga cctacctttt
    13441 tcaggagcca gtagcagata tgggggagct ggttagcctt ttacatcaga tgttggctcg
    13501 taaggaccgt ttttactatg caatcataga caaggcgact ggtaaggctt tgggatcttt
    13561 ttctctcatg cgcattgacc agaataaccg agtaatagaa gtcggagcag tcactttttc
    13621 tccagagcta aggggtacac ggataggaac tgaagctcag tatctcctag ctcgctatgt
    13681 ttttgaggag ctaaactatc gtcgctacga gtggaaatgc gatgccttaa atctgccatc
    13741 cagacgagct gcggagcgtt tgagctttat ttatgaagga accttccgtc aggcagtggt
    13801 ttataaggga cgtacgagag atacggattg gttgtctatg attgataagg actggcctca
    13861 agtcaaagat cgtttggaaa catggttgcg tcctgaaaat tttgataaaa atggacagca
    13921 gtacaagagc ttgagagaac tttaagaggt gttgagatga ttactattaa aaagcaagaa
    13981 attgtcaagc tagaggatgt tttacatctc tatcaggctg tcggttggac aaattatacc
    14041 catcaaccag agatgctgga gcaggcctta tctcattcat tagtaattta tctggcactt
    14101 gatggtgatg ctgtggtggg cttgattcgt ttggttggag atggattctc atcagtattg
    14161 gttcaggatt taatcgtttt accaatctat cagcgtcaag gaattggtag tgccttgatg
    14221 aaagaggctt tagaggatta caaagatgcc tatcaagtcc agctggtgac agaagagaca
    14281 gaaagaacct tgggcttcta tcgttctatg ggctttgaaa tcttatccac ctataattgt
    14341 atagggatga cttggatgaa tcgtaaaaaa taacaaaact tgttttttct taagcaaaat
    14401 ttaaggatgg tctagtatta tatagtcatt aaataaagac ctcctaactt tatttaataa
    14461 aatcctaaac ttttcttttt cataataatc tcccttaact ccacccaatc aggtggagtt
    14521 ttttagctct atttcaggct tttggggact attctaaaaa taatttttcg atatttttcg
    14581 gtatttttcg gattttggtc ggggaattgg cggggacttt tttagcgaat ataactaaga
    14641 aataggtctg tggtcgcttc agctagttca aactcaattt gattgtaagt gactgttaat
    14701 tgaagaactg gaactactgt aataatgatt ttgcttgtct agtagtggcg tattaaatga
    14761 gaagtgacat gtaagattgt ctcttcgttt acgaaatcaa aatttctatg aaattgatag
    14821 aatccctaac gttctcttaa tcttaaccgt cttgtcgtac agcggttgaa gaaaatgtaa
    14881 acctttgaca aaattcgtga actatgggat aataaaaagg aattgagtac tagttctata
    14941 tcataggcta gaaaagaccc caagctcacg accaaataag cttgaggtct tttttgacac
    15001 tatttgtcct tgtttagcca tttatcgact atacgaagaa cgacaccgac cacaattggt
    15061 ccgatgatag ttttgagtac taattccatc atgggctatc tcacctcctt tcgtaggcgg
    15121 tgtagcagtg tcgtagaata ttataccaca taagtgctaa acttaggagt cacccaatca
    15181 ggtggctttt ttgtttgtgg cttggttttt tgatataata gagccatgag tagaatttta
    15241 gataatgaga taatggggga tgaggagtta gtagaacgca cgctccgtcc tcagtattta
    15301 cgtgaatata tcggacagga taaggtcaag gaccagctac aaatctttat tgaagctgcc
    15361 aaaatgcggg atgaagcgct ggatcatgtg ctcttatttg ggcctccagg tctcgggaaa
    15421 acgaccatgg cctttgttat tgccaacgaa ctgggagtca atcttaagca gacgtcgggt
    15481 ccagtcattg aaaaagccgg agatctggta gctattttga atgagttaga gcctggggat
    15541 gtacttttta ttgatgagat ccatcgtttg ccaatgtcag tggaagaggt gctttatagt
    15601 gctatggagg acttctacat agatattatg attggggctg gtgagggtag tcgtagtgtt
    15661 catttggagt taccaccttt taccttgatt ggtgcgacga ctcgggctgg tatgctctcc
    15721 aatccgctac gggcacgttt tgggattaca ggccatatgg agtattatgc ccatgctgac
    15781 ttgacagaaa ttgtcgagcg gacggcagat atttttgaga tggaaatcac tcatgaggca
    15841 gcatctgagt tggccctacg tagtcgtggg acccctcgta ttgccaatcg tctcctcaag
    15901 cgcgtgcgcg attttgccca gataatgggg aatggggtaa ttgatgatat tattaccgat
    15961 aaggctttga ctatgctgga tgttgaccat gaaggtttgg actatgtgga tcaaaaaatc
    16021 cttcgtacca tgattgagat gtacagtgga ggacctgttg gtctaggaac tctttctgtg
    16081 aatatcgccg aagagcgtga gacagttgaa gatatgtatg agccttactt gattcaaaaa
    16141 ggttttatca tgcggacacg gtctggacgg gtggcgactg ctaaggcata tgagcactta
    16201 ggttatgaat acagtgaaaa ataagcaaga aatcttagag gcttttagag aaaatccaga
    16261 tatgatggcc attctgacga tcatccgaga ccttggtctg aaagactcgt ggttggcagc
    16321 aggttctgtc agaaatttca tttggaatct tttgtcagac aaatcccctt ttgatcatga
    16381 aacagatata gatgtgattt tctttgatcc agatttttct tatgaggaaa ccttattact
    16441 ggagaaaaag ctgagagagg attttcctca gtaccagtgg gaattgaaaa atcaggtcta
    16501 tatgcatcag cacagtcctc acactgcttc ctataccagt tctcgtgatg ctatgagtaa
    16561 gtatccagaa cggtgtacgg cagttggact gcgcttgaat gaagaatcag attttgaact
    16621 ctatgcacct tatggtttgg aggatatttt gaattttcaa gttcgtccaa ctcctcattt
    16681 cttagaaaat gaagaccgaa tggaactcta tcaaacacgt ttatccaaga aaaattggca
    16741 ggagaaatgg aaaaatttga tttttaaaaa tacttaagga aactttaagc tagggagtgt
    16801 acactaagtt cataagttaa gaagacctta acttaaactc ctaaaacttt ttcataataa
    16861 tctccctata aaaataaagt cgcccaatca ggcggcttat ttttttgaaa aatgggcatg
    16921 gtgcctgaga ataaatagct tagtgataga agaaaatggg gaaatatggt ataatgaaac
    16981 gatagatttt tgaataggaa taagatcatg tttggatttt ttaagaaaga taaggctgtg
    17041 gaagtagagg ttccgacaca ggttcctgct catatcggca tcatcatgga tggcaatggc
    17101 cgttgggcta aaaaacgtat gcaaccgcga gtttttggac ataaggcggg catggaagca
    17161 ttgcaaaccg tgaccaaggc agccaacaaa ctgggcgtca aggttattac ggtctatgct
    17221 ttttctacgg aaaactggac ccgtccagat caggaagtca agtttatcat gaacttgcca
    17281 gtagagtttt atgataatta tgtcccggaa ctacatgcga ataatgttaa gattcaaatg
    17341 attggggaga cagaccgcct gcctaagcaa acctttgaag ctttaaccaa ggctgaggaa
    17401 ttgactaaga acaacacagg attgattctt aattttgctc ttaactatgg tggacgtgct
    17461 gagattacac aggcgcttaa gttgatttcc caggatgttt tagatgccaa aatcaaccca
    17521 ggtgacatca cagaggaatt gattggtaac tatctcttta ctcagcattt gcctaaggac
    17581 ttacgagacc cagacttgat tatccgtact agtggagaat tacgtttgag caattttctt
    17641 ccatggcagg gagcctatag tgagctttat tttacggaca ccttatggcc tgattttgac
    17701 gaagcggcct tgcaggaagc tattcttgcc tataatcgtc gtcatcgccg atttggagga
    17761 gtttaggagg aaatatgacc caggatttac agaaaagaac cttgtttgca gggattgccc
    17821 tggctatttt cctaccaatt ttaatgattg ggggcctctt gcttcagata gcaatcggaa
    17881 tcatagccat gctagccatg catgaacttt tgaagatgag aggtctagag accatgacga
    17941 tggagggcct cttgaccctc tttgcaacct ttgcattgac cattcccttg gagaattacc
    18001 tgactttttt gccagttgat gggaatgtgg ttgcctatag tgttttgatt tcaatcatgt
    18061 taggaacgac cgtttttagc aagtcttata cgattgagga tgcggttttc cctcttgcta
    18121 tgagcttcta cgtgggcttt ggatttaatg ctttactaga tgctcgtgtt gcaggtttgg
    18181 acaaggctct cttagccttg tgtatcgtct gggcgacaga cagtggtgcc tatcttgttg
    18241 ggatgaacta tgggaaacga aagttagcac caagggtatc gcctaataaa acccttgagg
    18301 gtgccttggg tggtatttta ggagcaattt tagtaaccat tatctttatg atagttgaca
    18361 gtacagttgc tcttccatat ggaatttaca agatgtcagt ctttgctatt ttctttagca
    18421 ttgctggaca atttggtgat ttactagaaa gttcgatcaa acgtcatttt ggtgttaagg
    18481 attctgggaa atttatccct ggacatggtg gtgttttgga tcgtttcgat agtatgttgc
    18541 ttgtatttcc aatcatgcac ttatttggac tcttttaatc aaaagacgga ggaaacgcta
    18601 tgctcggaat tttaaccttt attctggttt tcgggattat tgtagtggtg cacgagttcg
    18661 ggcacttcta ctttgccaag aaatcaggga ttttagtacg tgaatttgcc atcggtatgg
    18721 gacctaaaat ttttgctcac attggcaagg atggaacggc ctataccatt cgaatcttgc
    18781 ctctgggtgg ctatgtccgc atggccggtt ggggtgatga tacaactgaa atcaagacag
    18841 gaacgcctgt tagtttgaca cttgctgatg atggtaaggt taaacgcatc aatctctcag
    18901 gtaaaaaatt ggatcaaaca gccctcccta tgcaggtgac ccagtttgat tttgaagaca
    18961 agctctttat caaaggattg gttctggaag aagaaaaaac atttgcagtg gatcacgatg
    19021 caacggttgt ggaagcagat ggtactgagg ttcggattgc acctttagat gttcaatatc
    19081 aaaatgcgac tatctggggc aaactgatta ccaattttgc aggtcctatg aacaatttta
    19141 tcttaggtgt cgttgttttt tgggttttaa tctttatgca gggtggtgtc agagatgttg
    19201 ataccaatca gttccatatc atgccccaag gtgccttggc caaggtagga gtaccagaaa
    19261 cggcacaaat taccaagatt ggctcacatg aggttagcaa ctgggaaagc ttgatccaag
    19321 ctgtggaaac agaaaccaaa gataagacgg caccgacttt ggatgtgact atttctgaaa
    19381 aggggagtga caaacaagtc actgttacac ccgaagatag tcaaggtcgt taccttctag
    19441 gtgttcaacc gggggttaag tcagattttc tatccatgtt tgtaggtggt tttacaactg
    19501 ctgctgactc agctctccga attctctcag ctctgaaaaa tctgattttc caaccggatt
    19561 tgaacaagtt gggtggacct gttgctatct ttaaggcaag tagtgatgct gctaaaaatg
    19621 gaattgaaaa tatcttgtac ttcttggcaa tgatttccat caatattggg atttttaatc
    19681 ttattccgat tccagccttg gatggtggta agattgtgct caatatccta gaagccatcc
    19741 gccgcaaacc attgaaacaa gaaattgaaa cctatgtcac cttggccgga gtggtcatca
    19801 tggttgtctt gatgattgct gtgacttgga atgacattat gcgactcttt tttagataat
    19861 cgaggaatat tatgaaacaa agtaaaatgc ctatcccaac gcttcgcgaa atgccaagcg
    19921 atgctcaagt tatcagccat gctcttatgt tgcgtgctgg ttatgttcgc caagtttcag
    19981 caggtgttta ttcttatcta ccacttgcca atcgtgtgat tgaaaaagct aaaaacatca
    20041 tgcgccaaga attcgaaaag attggtgctg ttgagatgtt ggctccagcc cttcttagtg
    20101 cagaattgtg gcgtgaatca ggtcgttacg aaacctatgg tgaagacctt tacaaactaa
    20161 aaaaccgtga aaaatcagac tttatcttag gtccaactca cgaagaaacc tttacagcta
    20221 ttgtccgtga ttctgttaaa tcttacaagc aattgccact caacctttat caaattcagc
    20281 ccaagtatcg tgatgaaaaa cgcccacgta atggacttct tcgtacacgt gagtttatca
    20341 tgaaggatgc ttatagtttc cacgctaact atgatagttt ggatagtgtt tatgatgagt
    20401 acaaagcagc ctatgagcgt attttcactc gtagtggttt agacttcaag gctattattg
    20461 gtgacggtgg agccatgggt ggtaaggata gccaagaatt tatggccatt acatctgctc
    20521 gtacagacct tgaccgctgg gttgtcttgg acaagtcagt tgcctcattt gacgaaattc
    20581 ctgcagaagt gcaagaagaa atcaaggcag aattgctcaa atggatagtc tctggtgaag
    20641 ataccattgc ttactcaagt gagtctagct atgcagctaa cttagaaatg gcaacaaacg
    20701 agtacaaacc aagcaaccgt gttgtcgctg aagaagaagt tactcgtgtt gcaacgccag
    20761 atgttaaatc aattgatgaa gttgcagctt tcctcaatgt tccagaagaa caaacgatta
    20821 aaaccctctt ctacattgca gatggtgagc ttgttgcagc ccttctagtt ggaaatgacc
    20881 aactcaacga agtcaagttg aaaaaccact taggagcaga tttctttgac gttgctagcg
    20941 aagaagaagt ggcgaatgtt gttcaagcag gatttggttc acttggacca gttggtttgc
    21001 cagagaatat taaaattatt gcagatcgta aggtgcaaga tgttcgcaat gcagttgtcg
    21061 gtgctaacga agatggctac cacttgactg gtgtgaaccc aggccgtgat tttactgcag
    21121 aatatgtgga tatccgtgaa gttcgtgagg gtgaaatttc cccagatgga caaggtgtcc
    21181 ttaactttgc gcgtggtatt gagatcggtc atattttcaa actcggaact cgctactcag
    21241 caagcatggg agcagatgtc ttggatgaaa atggtcgtgc tgtgccaatc atcatgggat
    21301 gttacggtat cggtgtcagc cgtcttcttt cagcagtgat ggagcaacac gctcgcctct
    21361 ttgttaacaa aacgccaaaa ggtgaatacc gttacgcttg gggaatcaat ttccctaaag
    21421 aattggcacc atttgatgtg catttgatta ctgtcaatgt caaggatgaa gaagcgcaag
    21481 ccttgacaga aaaacttgaa gcaagcttga tgggagctgg ttatgaagtc ttgacagatg
    21541 accgtaacga acgtgtcggt gttaaattta gcgatagtga cttgattggt cttccaatcc
    21601 gtatcactgt tggtaaaaaa gcggccgatg gcattgtaga agttaagatc aaggcaactg
    21661 gtgacaccat tgaggttcat gcagataacg tgcttgaaac gcttgaaatc ctaagcaaga
    21721 aataaaaact ataatcagaa gaaaaacaag gaaaaaatgt aactagtttt taccttgttt
    21781 tttctgtata atgggagaaa tgagtagata aagaggtaaa tgttatgcta agatttccaa
    21841 aggattttgt ctggggatcc tctacttctg gaccgcagac agaaggacgt gtagctggtg
    21901 acggtaaggg agacaatctc tgggattact ggttccaagt ggagccaaat cgttactata
    21961 atgggattgg ttcagataag acatcgactt tttatgaaaa ttgggagcgg gatattgagc
    22021 ttttgttaga gactggtcac acagtctttc ggacttctat tcagtggtca cggatttttc
    22081 cacaaggctg tggaaaagtc aaccctcaag gtgtggattt ttatcgtaag gtctttgagg
    22141 ctattaaggc taaaggaatt cgtctgttag tcaatctcta tcattttgat ttaccttttg
    22201 cccttcaaga ggatggtgat ggttgggaaa ataaggcgac agtctcagcc tatgaagact
    22261 atgctcgttt ttgttttgag acttatggag atttagtgga tcaatggatt acctttaacg
    22321 agctcatcgt tcctgtagaa tttggttatt tttatgatgc ccattatcca cataaggtgg
    22381 atgcagaggc agctgttaag gtagcctatc atacacaatt ggccagcagc cgggctgtta
    22441 aggcttgcca tgaacttttg cctgattcca agattgggat tgtcctcaac ttgacaccgg
    22501 cttatccacg tagccagcat cctgctgatg tcaaggcagc tcgtattgcg gccctttttc
    22561 aggcccaatc tttcttagat ccatctgtct tggggactta tccacaggag ttggtagaaa
    22621 tcttgcatga acacggtctt ttacctgatg ctacagagga agagttggaa ctcattcatg
    22681 ataatacggt ggacttcctt ggtgtgaact actatcaacc tttgcgtgtt atggctcctc
    22741 gatttgctaa gcatccagag agtccactct taccagaaca tttttacgag ccttatgtga
    22801 tgcctggacg taaaatcaat tctcaccgtg gttgggagat ttatgagcaa gggatttatg
    22861 acatcgccca aaatatcaag gaaaattatg gcaatattga atggatgttg actgagaatg
    22921 gtatgggtgt tgaaggggaa gaaaaattcc gtcaagatgg aatgattcaa gatgattacc
    22981 gtattgactt tgtaaaaggt catcttcgtg aacttcaccg tgccattgaa gatggtgcca
    23041 actgtaaggg ctacttgatt tggaccttta ttgactgctg gtcatggctc aacagctata
    23101 aaaatcgcta tggtttggtc gaattagact tggaaacgca agaacgtcgt ctgaagaaat
    23161 caggccactg gttcaaaaaa ttaagcgata ataatggatt ttaaaaagga ctctgactga
    23221 ttatcccaat cggtcagagt tttttgctta caggagctta atttgaacta taccaatttt
    23281 tactcttgac aagtgaaaga aacaagtata tactgttttt gctgattcta taaaagatga
    23341 attagactat accaatttta aggagaaagc acagcttgcc tgtgtcgtat atactatgtg
    23401 tggaattgtt ggtgttgttg gaaacacaaa tgcaactgat attttgattc aagggcttga
    23461 aaagcttgaa taccgtggct atgattctgc gggaattttt gtcctagatg gtgctgataa
    23521 ccatttggtg aaggctgttg gtcgtatcgc agaattgtct gccaagacag ctggtgttga
    23581 gggaacaact ggtatcggac atactcgttg ggcaactcat gggaaaccaa cggaagacaa
    23641 tgctcaccca caccgctctg agacagaacg ttttgtcttg gttcacaatg gggtgattga
    23701 aaactacctt gaaattaaag aagaatacct tgctgggcac cacttcaaag ggcaaacaga
    23761 tacggaaatc gccgtacatt tgattggaaa atttgcggaa gaagacggtc tctcagttct
    23821 tgaagccttt aaaaaagctc ttcatattat ccgtggttca tatgcctttg ccttgattga
    23881 ctctgaaaat ccagatgtca tctatgtagc gaaaaacaaa tctccacttt tgattggtct
    23941 tggggaaggc tacaatatgg tctgctcaga tgctatggct atgattcgtg aaaccaacca
    24001 atacatggaa attcatgacc aagagttggt aatcgtcaag gctgatagcg tggaagttca
    24061 agactatgat ggaaatcgtc gtgagcgtgc tagctacact gctgaacttg acttgtcaga
    24121 tatcggtaag ggaacttacc cttactacat gctcaaggaa attgacgagc aaccaactgt
    24181 tatgcggaaa ctcatccaag cctacacaga tgaggctggt caagttgtcg tagacccaga
    24241 tatcattaag gctgttcaag acgcagaccg catctacatc cttgcagctg gaacatctta
    24301 ccatgcagga tttgcttcta agaagatgtt ggaagaattg acagatacac cagttgaact
    24361 tggaatctca tctgagtggg gctacggtat gccacttctc agcaagaaac cactcttcat
    24421 ctttatcagc caatctggtg aaacagcgga tagtcgtcaa gttttggtca aggctaatga
    24481 aatgggaatt ccaagcttaa cagtgacaaa tgttccaggt tcaaccctct cacgtgaagc
    24541 caactatacc atgctccttc acgcaggtcc tgaaattgcc gtggcatcaa ctaaagccta
    24601 tacagcgcaa atcgcagccc ttgccttcct tgcaaaagca gtcggagaag caaatggtaa
    24661 tgctaaagcg caagcctttg acctggttca tgaattgtca atcgtagctc agtctattga
    24721 atcaactctt tcagagaaag aaaccattga agccaaggtt cgtgaacttc ttgaaacaac
    24781 tcgtaacgcc ttttacatcg gacgtggtca agattattac gtagccatgg aagcaagtct
    24841 caaactcaaa gagatttctt atatccagtg tgaaggtttt gcggcaggag aactcaagca
    24901 cggaaccatt gccttgattg aagaaggaac gcctgttttg gctctcttgt cagatccagt
    24961 tcttgccaac catactcgtg gaaatatcca agaggtcgca gcccgtggtg ccaaagtcct
    25021 cactatcgca gaagagaatg tagccaaaga taccgacgat atcgtcctta cgaccgtaca
    25081 tccatacctc tcaccaattt caatggtcgt accaacgcaa ttagtcgctt actttgcaac
    25141 cctccaccgt ggcctcgatg tggacaaacc acgtaacctt gccaagtcag taacggtaga
    25201 ataagctaaa aaagtctagt tatctaggct ttttcttgtg agcaaattgg ttgcttgtac
    25261 tcaagattcg tgttatactc ttagaaaatc tcttcaaacc acgtcaccgt cgccttgccg
    25321 taggtatggt tactga
//
LOCUS       DAVAZT010000031        24327 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVAZT010000031 DAVAZT010000000
VERSION     DAVAZT010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24327
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.031"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..618)
                     /locus_tag="VQT45_001183"
     CDS             complement(<1..618)
                     /locus_tag="VQT45_001183"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HET2359511.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEK"
     gene            complement(769..2079)
                     /gene="secY"
                     /locus_tag="VQT45_001184"
     CDS             complement(769..2079)
                     /gene="secY"
                     /locus_tag="VQT45_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HET2359512.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            complement(2092..2532)
                     /gene="rplO"
                     /locus_tag="VQT45_001185"
     CDS             complement(2092..2532)
                     /gene="rplO"
                     /locus_tag="VQT45_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HET2359513.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            complement(2677..2901)
                     /gene="rpmD"
                     /locus_tag="VQT45_001186"
     CDS             complement(2677..2901)
                     /gene="rpmD"
                     /locus_tag="VQT45_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HET2359514.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            complement(2873..3367)
                     /gene="rpsE"
                     /locus_tag="VQT45_001187"
     CDS             complement(2873..3367)
                     /gene="rpsE"
                     /locus_tag="VQT45_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HET2359515.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            complement(3385..3741)
                     /gene="rplR"
                     /locus_tag="VQT45_001188"
     CDS             complement(3385..3741)
                     /gene="rplR"
                     /locus_tag="VQT45_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HET2359516.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(3825..4361)
                     /gene="rplF"
                     /locus_tag="VQT45_001189"
     CDS             complement(3825..4361)
                     /gene="rplF"
                     /locus_tag="VQT45_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HET2359517.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            complement(4553..4951)
                     /gene="rpsH"
                     /locus_tag="VQT45_001190"
     CDS             complement(4553..4951)
                     /gene="rpsH"
                     /locus_tag="VQT45_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HET2359518.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(5236..5505)
                     /gene="rpsN"
                     /locus_tag="VQT45_001191"
     CDS             complement(5236..5505)
                     /gene="rpsN"
                     /locus_tag="VQT45_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HET2359519.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            complement(5523..6065)
                     /gene="rplE"
                     /locus_tag="VQT45_001192"
     CDS             complement(5523..6065)
                     /gene="rplE"
                     /locus_tag="VQT45_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HET2359520.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            complement(6089..6394)
                     /gene="rplX"
                     /locus_tag="VQT45_001193"
     CDS             complement(6089..6394)
                     /gene="rplX"
                     /locus_tag="VQT45_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HET2359521.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            complement(6472..6840)
                     /gene="rplN"
                     /locus_tag="VQT45_001194"
     CDS             complement(6472..6840)
                     /gene="rplN"
                     /locus_tag="VQT45_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HET2359522.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            complement(6866..7126)
                     /gene="rpsQ"
                     /locus_tag="VQT45_001195"
     CDS             complement(6866..7126)
                     /gene="rpsQ"
                     /locus_tag="VQT45_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HET2359523.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            complement(7151..7357)
                     /locus_tag="VQT45_001196"
     CDS             complement(7151..7357)
                     /locus_tag="VQT45_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HET2359524.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            complement(7367..7780)
                     /gene="rplP"
                     /locus_tag="VQT45_001197"
     CDS             complement(7367..7780)
                     /gene="rplP"
                     /locus_tag="VQT45_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HET2359525.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(7784..8437)
                     /gene="rpsC"
                     /locus_tag="VQT45_001198"
     CDS             complement(7784..8437)
                     /gene="rpsC"
                     /locus_tag="VQT45_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HET2359526.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(8450..8794)
                     /gene="rplV"
                     /locus_tag="VQT45_001199"
     CDS             complement(8450..8794)
                     /gene="rplV"
                     /locus_tag="VQT45_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HET2359527.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            complement(8806..9087)
                     /gene="rpsS"
                     /locus_tag="VQT45_001200"
     CDS             complement(8806..9087)
                     /gene="rpsS"
                     /locus_tag="VQT45_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HET2359528.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            complement(9191..10024)
                     /gene="rplB"
                     /locus_tag="VQT45_001201"
     CDS             complement(9191..10024)
                     /gene="rplB"
                     /locus_tag="VQT45_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HET2359529.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(10042..10338)
                     /locus_tag="VQT45_001202"
     CDS             complement(10042..10338)
                     /locus_tag="VQT45_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HET2359530.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(10338..10961)
                     /gene="rplD"
                     /locus_tag="VQT45_001203"
     CDS             complement(10338..10961)
                     /gene="rplD"
                     /locus_tag="VQT45_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HET2359531.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            complement(10986..11612)
                     /gene="rplC"
                     /locus_tag="VQT45_001204"
     CDS             complement(10986..11612)
                     /gene="rplC"
                     /locus_tag="VQT45_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HET2359532.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            complement(11828..12136)
                     /gene="rpsJ"
                     /locus_tag="VQT45_001205"
     CDS             complement(11828..12136)
                     /gene="rpsJ"
                     /locus_tag="VQT45_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HET2359533.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(12402..13019)
                     /locus_tag="VQT45_001206"
     CDS             complement(12402..13019)
                     /locus_tag="VQT45_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HET2359534.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            complement(13016..13606)
                     /gene="nrdG"
                     /locus_tag="VQT45_001207"
     CDS             complement(13016..13606)
                     /gene="nrdG"
                     /locus_tag="VQT45_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HET2359535.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVAGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKEIYEQVKRE"
     gene            complement(13599..14105)
                     /locus_tag="VQT45_001208"
     CDS             complement(13599..14105)
                     /locus_tag="VQT45_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2359536.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDVEDFSYEEWL
                     EGNRNKEMGIWLPENRVPSIQFVLFGESGCALGFLNLRLRLNEGLLNYAGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            complement(14149..14289)
                     /locus_tag="VQT45_001209"
     CDS             complement(14149..14289)
                     /locus_tag="VQT45_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359537.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            complement(14301..16508)
                     /gene="nrdD"
                     /locus_tag="VQT45_001210"
     CDS             complement(14301..16508)
                     /gene="nrdD"
                     /locus_tag="VQT45_001210"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HET2359538.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNCRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            complement(16628..18166)
                     /locus_tag="VQT45_001211"
     CDS             complement(16628..18166)
                     /locus_tag="VQT45_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET2359539.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            complement(18203..18346)
                     /locus_tag="VQT45_001212"
     CDS             complement(18203..18346)
                     /locus_tag="VQT45_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359540.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            complement(18424..19956)
                     /gene="cls"
                     /locus_tag="VQT45_001213"
     CDS             complement(18424..19956)
                     /gene="cls"
                     /locus_tag="VQT45_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HET2359541.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            complement(20102..20659)
                     /locus_tag="VQT45_001214"
     CDS             complement(20102..20659)
                     /locus_tag="VQT45_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HET2359542.1"
                     /translation="MTPLFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQQVQQPAQQPAQQNTNTANAGGNQNQAAPVQNQPVAQP
                     TDIDGTYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKI
                     YTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            complement(20656..21906)
                     /locus_tag="VQT45_001215"
     CDS             complement(20656..21906)
                     /locus_tag="VQT45_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET2359543.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRIQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFEMLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNFSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGALKRKD
                     YQGMLGYLTEKLPQVELKVTGFDYQGALDERDVTGYDIVSSCREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            complement(22114..22419)
                     /locus_tag="VQT45_001216"
     CDS             complement(22114..22419)
                     /locus_tag="VQT45_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HET2359544.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            complement(22435..22854)
                     /gene="ruvX"
                     /locus_tag="VQT45_001217"
     CDS             complement(22435..22854)
                     /gene="ruvX"
                     /locus_tag="VQT45_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HET2359545.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPLDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            complement(22858..23124)
                     /locus_tag="VQT45_001218"
     CDS             complement(22858..23124)
                     /locus_tag="VQT45_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HET2359546.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            complement(23211..23780)
                     /locus_tag="VQT45_001219"
     CDS             complement(23211..23780)
                     /locus_tag="VQT45_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET2359547.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            complement(23846..24244)
                     /gene="spx"
                     /locus_tag="VQT45_001220"
     CDS             complement(23846..24244)
                     /gene="spx"
                     /locus_tag="VQT45_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HET2359548.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
BASE COUNT         6740 a         5398 c         4559 g         7630 t
ORIGIN      
        1 tttttcaata tctgagaaga catcattgat atcttgatta ccttcgatgt catgaaccaa
       61 acctttggca cggtagtgag caatgattgg ttctccttga gcaatattaa catccaaacg
      121 acgttttact gtctcaggct tatcatcttc acgttggtag taatcttctt ctttatagtc
      181 aactggtggg ttaaagacct tgtggaaagt ttctccagtt acgcggtgga tgatacggcc
      241 actcaaacgt tccaagaggc tgtcagggtt cacttcaata ttgataatac cttctagttc
      301 aatgccaagt tcagccaatg ttttgtccaa ggcatgagct tgttcaattg tacgtgggta
      361 accatccaat aagaatcctg tttctttaat atcatcttgt gaaaggcgtt cttttacgat
      421 tccatttgta acttcgtcag gaaccaattc acccttgtca atatatgact tagcaagaac
      481 acccatttca gtttgatttg ccattgcagc gcggaacata tcacctgttg agatatgtgc
      541 aacatggaat tgttctacga tttttgctgc ttgagttccc ttacctgcac caggtaagcc
      601 cataatcaaa agattcatga tttgatctcc ttattttatt tttaaataga agcaaaaagt
      661 cttttcaccc ctatttaaaa acaaaataga agaggggaga tccaactctt acaaatgtca
      721 gagtttaaac ctccactccc tcagtattta ctgattcagt aaatactttt attctgttct
      781 gtccatgaaa ccaacatact tacgtttcaa taggtaacct tccaattgct tgattccttc
      841 gatacctgta gagataatga tcaagagact tgttccacca aaggcaacaa catcagaaag
      901 accaaataca tctttagctg caatcggtaa aatggaaatc acaccaagga agagggaacc
      961 aacagttgca agacgacgaa gaagtttaga catatattct tctgtacctt taccaggacg
     1021 aactccatgg atataggcac cactcttttg taggctctct gctgcttttt caggattaat
     1081 ctgtacaaac gtatagaaga atgtaaagag aataatcaac aaagcataca tggcaatacc
     1141 agttggagaa gtagttgcca acatctcttg tgctaccctt acccaagccc aatcatgacc
     1201 tgtggcactc aaaaactgaa gaatagccgc aggcgctgca gtaatcgaac tggcaaagat
     1261 aacagggata actccagcag ggtttacctt taacggaagg taagagctag atggagcacc
     1321 ttgtgcaacc ttagtatatt ggattggaat tttgtattct gcttgttgaa cataagttgt
     1381 aaagtaaata atcaacaata cagtaataat caaaatgatt acgaaaatga tagatgaagt
     1441 gatacggcta cttgggacgt tcacaaagta gtccacatag atgccctgaa tcatctctgg
     1501 aattgaggaa acaatcccgg caaagataat catggaaaca ccgtttccgt atcccttatc
     1561 tgtaatttgc tcacccaacc aagtgacaat catactacca gctgttaaga tgataccaat
     1621 cgtcagaaaa acttgtggag ttaaagcagt tttaatcaat tgagctccag ccaaggtatt
     1681 aaaaccagct gtaatcccga tagattgcac aaaagcgaga actagagcaa tataacgagt
     1741 agcttgattc aattttcttc gacctacttc cccttgttta ccccactcta caaacttggg
     1801 taaaatatcc atttgcaaga gttggacaac aatagaagcg gtgatatagg gactaactcc
     1861 tagggcaaaa atcgaaaagt tttttagggc attccccgac accaagctca acatgtttaa
     1921 gaaggataat ccacttaaag cattcaagct attggcattc acaccaggaa ctgtaatgct
     1981 agttccgata cgaaagacca aaacgataaa aattgtaaat aaaatttttg atcgaacctg
     2041 cttgacttta agagcttctc ttaataattt aaaaaacata ggtcacctct cttagatgac
     2101 ttctactgaa ccacctttag cagtgatagc ttcttcagct gatttagaga atttagctgc
     2161 tttcacagtc aatttcttag tcaactcacc gttaccaaga attttaatac ctgacttttc
     2221 agctttaaca attcctgctt cgataagaac aactggagtt acttcagcac catcttcaaa
     2281 gacgttcaat tggtcaaggt tcacaattgc gtattcttta gcgttgatgt tagtgaatcc
     2341 acgttttgga agacgacgga acaatggagt ttgtccacct tcaaaaccaa ggcgaactcc
     2401 gccaccgcta cgagcttttt gacctttttg accacgacca gatgttttac cgttacctga
     2461 tgaagtacca cgaccaacgc ggttacgtac tttacgagaa ccttctgcag gtttcaattc
     2521 atgaagtttc atttttattt tctcctcttt tgtaaaatgc tagcgccgat aagggagaaa
     2581 aggttgtctc ccccatcaac tcgcctatac gatgtcatca tagatgacta tatctagttt
     2641 taggggatgg tacagtgcac atcccctaaa acttcattag tttacttctt caactgttac
     2701 taagtgagat actgctgtaa tcataccacg gatagcagcg ttatcttctt taataacaga
     2761 gctgttcaat ttgccaagtc caagtgctac aacagtttta cgttgtgatg gaatgcgtcc
     2821 gattggagac ttagtcaaag taattttaat ttgagccatt ttatcccctt tcttatgcca
     2881 aatcagaaac tgaaatacca cgaagggcag caatttcttc agcgcgtttc aattgtttca
     2941 aaccttcaac agttgcacga acaatgttga ttggagtgtt agaaccaagt gatttagatg
     3001 taatatctgc cacacctgcc aattccacaa cggcacgaac tgcaccacca gcggcaactc
     3061 cagaaccttc tacagcaggt ttcaacaata ctttagctcc accgaattct gaaagaactt
     3121 cgtgtgggat tgttgttcca accataggaa cttcgatcaa gtttttctta gcatcatcta
     3181 ctgctttacg gattgcttct ggaacttctt gagctttacc agtaccaaat cctacgcgac
     3241 cattgtggtc accaacaaca acaagagctg cgaaacgaag acgacgtcca cctttaacaa
     3301 cttttgtaac acggttgaca gcaactacgc gttcttctaa ttcaactgca ttgtctttaa
     3361 atgccatttt ctagtgtcct cctattagaa tttcaatccg ttttcacgag ctgcatcagc
     3421 caaagctttc acacgtccgt gatatagata tccaccgcgg tcgaacacca cttctgaaat
     3481 acctttagcg tttgcacgtt ctgcaacgag tttaccgaca gcaacggctt gttcagtttt
     3541 agttcctttt gaaacttctt tatcaagagt tgaagcactt gcgagcgtta cacccgctac
     3601 gtcatcaatc acttgagcgt agatgcctgt attagaacgg aatacgttca aacgtgggcg
     3661 atcagcagtt ccagagagtt ttccgcgaac gcgacggtgg cgtttttggc ggagtttgtt
     3721 tttatctggt tttgaaatca cagttttcac ctctttagtt ttaaatcgtg tgctatgcac
     3781 aaagttggaa aataggttgg tggttgatga tcaaccactc aacattattt acctgtttta
     3841 ccttctttac ggcgaacgaa ttcaccaacg taacggatac ctttaccttt atatggttct
     3901 ggtgaacgaa ggctacgtac gtaagcagct gtttgaccaa ctacttcttt tgaaattccg
     3961 ctaacaacga ttgttgttgg gtttggaagt tcaaaagtaa ttccttctgg agcttcaact
     4021 tcgtctggat gagatttacc aacagccaaa acaagtttag atccttgaag ctgtgcacgg
     4081 taaccaaccc cacgcatttc aagttctttc ttgaatcctt ctgatacacc aacaaccatg
     4141 ttgttcaaaa gggcacgagt agttccgtgg atagttttca tttcttttga atcgtttgga
     4201 cggtgaagag ttatttcagt accttccaca cggatttcaa tatcttttga gaactcacga
     4261 gtaagttctc ctttaggtcc ttttacagtt acaacgttgt cattgttagc gagttcaaca
     4321 ccagcaggca acacgataac tttattacca atacgtgaca tgtttatttt ctcctgttaa
     4381 attgtcaggc cagaacggcc agttttcacg gggttcagat acttatttag ttcaagagct
     4441 gaactgaaca cgctctaaga actgtgcaaa atagataagt tggcttgttt gtaaacaaac
     4501 ttctccaact tcctaatttt gctttgttct ttacgagctt tgtatcttga ttttaccaaa
     4561 cgtaagcgat aacctcacca ccaacattct tttggcgtgc ttctttatca gtaagcaaac
     4621 cttcagaagt tgaaaggatg gcaattccaa gtccgttaag aacttttgga aggtcttcac
     4681 gttttttgta gacacgaagt cctggtttag aaacacgttt caagttagtg ataactttct
     4741 caccatttgg tccgtattta agaaatacac ggatgacgcc ttgtttgtca tcttcaatga
     4801 tttcaacgtt ttttacaaaa ccttcgcgtt taaggatttc agcaatccct tttttgatgt
     4861 ttgatgcagg tacttcaagt acttcgtgtt tagcttggtt agcattacga atacgagtta
     4921 ggaagtctgc gattgggtca gtcataacca ttttgttttt ctcctcttac tagtagtttg
     4981 caagttgcac ttgctagtta atacatgata caaagagcgt aacagcacga gcaaaaatag
     5041 acaatttaat gcagaagcaa tgctccaaag caaattggtc ttttttgcca aagctgtagc
     5101 tcgtgttcaa attggcaagc ccaattgaac ccgggctaaa ctctgtgtga aaaagataaa
     5161 ctttcctaga aactttagtt tcttcgtcaa gtttcctatt tttacttgga gttttgacgc
     5221 tcttgatatc ttaaattacc aagatgcttt tgttacacca ggaatttgac ctttatgcgc
     5281 aagttcgcga aaagcgatac gactcagacc aaatttgcgg taaactgaat gtgggcgccc
     5341 cgtaactcta caacgattat gtaaacgagt cggtgaggcg ttgcgaggta atttagataa
     5401 accttcgtag tcccctgccg cctttaatgc agcacgtttt tcagcataac ggtcaacaat
     5461 tttttggcgt ttagcctctc tagctaccat tgatttttta gccattagat ttacctccta
     5521 tattattttg caaaaggcat tccaaggcct gtaagcaatg cacgtgactc ttcgtcagtg
     5581 ttagcagttg ttacgataac gatgtcaaga ccacgagttt tgtcaacgtc atcgaagttg
     5641 atttctggga agattaattg ttctttcaca ccaagtgtgt agttcccgcg tccatcaaat
     5701 gattttgttg gaacaccgtg gaagtcacgt acacgtggaa gtgaaactga taccaattta
     5761 tccaagaatt cgtacatacg ttcaccacga agggtaactt ttgcaccgat cgcaacacct
     5821 tcacgaagac ggaagccggc gattgatttt ttagctttag tgataagtgg tttttgacct
     5881 gagataagtg ccaattcttc agcagctttt tcaaggcttt tagcgtttga tacagcttca
     5941 ccaacaccca tgttcaaaac aatcttatct actttaggca cagccatcac tgatgagtag
     6001 ttgaattgtt ctgtcaaagc aggaactact tcattaagat atttttcttt taaacgattt
     6061 gccattatac ttctcctttc cttcgtgatt aatcaagcac ttcgcctgat tttttgttgt
     6121 agcgaacttt tttaccgtct acaaatttgt aaccaacacg accagctaca ccatttttgt
     6181 ccaaaacttg aacgtttgat acgtggatag ctgcttcttt ctcgatgata ccaccttgag
     6241 gaagctcgtt agttggacgt tggtgtttct taacaatgtt aacaccttca acgataactt
     6301 tgtttacttt tggaagggca gtaaggacaa cagcttctgt tcccttatct ttaccagcga
     6361 ttacgcgaac tttgtcgcct ttttttacaa acattaggtt tctccttgat ttttcttacg
     6421 cccataaggg caccctagct tgaagctagg ggactagttt gttcctaaaa attaaagtac
     6481 ttctggagca agtgacacga tcttcatgaa gccaccttca cgcaattcac gtgcaactgg
     6541 gccaaagata cgtgttccgc gaggagtttt gtcttcacgg atgataactg ctgcgttttc
     6601 gtcaaatttg atgtatgaac catcagcacg acgagcacct gatttagtac gaacgataac
     6661 tgctttaaca acgtcacctt ttttaaccgc accaccagga gtagcttgtt ttacagatgc
     6721 cacgataaca tcaccgatgt ttgcaaattt acgtcctgaa ccaccaagaa ctttgatagt
     6781 caagatttcg cgagcaccgc tgttgtctgc gactttcaaa cgagtttctg tttgaatcat
     6841 ttcagttttc tcctttcagg tttgattaga tgatgaccgc ttcttcaaca acttctacaa
     6901 gacggaaacg ttttgtagct gaaagcgggc gagtttccat gatacgtacg atatcgcctt
     6961 ctttggcaac attgttttca tcatgagctt tgtatttttt agagtagtta atacgtttac
     7021 catagactgg gtggttacgt tttgtttcaa ctacaactgt gattgtcttg tccattttgt
     7081 cagatacaac acgtccaaca agaactttac gattattgcg ttccattgaa atttctcctt
     7141 ccctagtcta ttatttcgct tcagattgaa ctgttttgat acgagcgatt tgttttttaa
     7201 cttctttcaa gcgagctgtt tgttccaatt gaccagtagc agcttggaaa cgaagttcaa
     7261 acaattcttt tttcaattcg ttttcgcgct tcgcgagttc ttcttgagaa agaccacgaa
     7321 gttctttaac aaattctttt acttcattaa gtttcatgcc ttctccttat tctgcttcac
     7381 gttttacgaa tttacattta actggcaatt tgtggctagc aagtcgaagc gcttcacgtg
     7441 caatctcttc agatacacca gcgatttcga acatcacttt accacgttta actggtgcta
     7501 cccaaccttc aggtgcccct ttaccagatc ccatacgcac accgatagct ttagcagtgt
     7561 atgatttgtg tgggaagatt ttaatccaaa ctttaccacc acgtttcatg taacgagtca
     7621 tggcgatacg agcagcttcg atttggcggt tagtgatcca gtggctagtt gtagcttgaa
     7681 gaccgtattc accgaatgct acttcttttc caccttttgc ttcaccgcgc atttttccac
     7741 ggaactcacg acggtgttta acacgtttag gtactaacat tggttattta cctcctttag
     7801 tgtttttacg agctggaaga acttcaccac ggtagatcca tactttaaca ccaagtttac
     7861 cgtatgtagt atctgcttct tcccaagcgt aatcgatatc tgcacgaagt gtgtgaagcg
     7921 gaacagttcc ttcagagtat ccttcagcac gggcgatatc tgcaccgttc aaacgacctg
     7981 atacttgagt tttgattcct ttagctccag cacgcattgc acgttggatt gcttgttttt
     8041 gtgcacgacg gaaagcaaca cgttgctcca attgacgagc aattccttca cctacaaggt
     8101 gagcatccaa atcaggttgt ttgatttcga tgatgttgat gtgtacttgt tttccagtca
     8161 atttgttaag ttttgcacgg agtgcatcaa cgttagcacc acctttaccg ataaccatac
     8221 ctggtttagc agtgtgaagt gaaacgttaa ctttgtttac tgcgcgttcg atttcaatag
     8281 ttgaaactgc tgcgtcagca agttcttttt gaacgaattt acggattgca agatcttcat
     8341 gaaggtaatc cgcgtattct ttttcagcat accatttggc atcccaatca cggatgatgc
     8401 cgacacgcat accaattgga tgtacttttt gacccacgat tttacctcct tatttttctg
     8461 caacagctac agtgatgtga gctgtacgtt tgttgattgg tgaagctgaa cctttcgcac
     8521 gtggacggaa acgtttcata gttggtcctt cgtttgcgaa tgcttcagat actaccaaat
     8581 tagctttatc caaaccaaag ttgttttcag cgttagctac agctgagttc aaaactttca
     8641 agatgatttc agcagctttg tttggagtga atgtcaagat tgcgattgca tcggctacgc
     8701 ttttaccacg gatgttatca agaacaagac gtgatttacg aggtgaaaca cgtactgtac
     8761 gagccattgc tttagctgaa gtaatttctg ccatttatgt tctccttatt ttctacgtgt
     8821 tttcttgtcg tctgcagcgt gacctttgta agtacgagtt ggtgcaaatt caccaagttt
     8881 gtggcctacc atgtcttctt ggatgtaaac aggtacgtgt ttacgtccgt cataaactgc
     8941 aatagtgtaa ccaatgaaac ttgggaagat cgttgaacga cgtgaccaag ttttaataac
     9001 ttttttcttt tcgtcgttag cttgagcttc aacttttttc atcaaatgct catcgacgaa
     9061 aggtcctttt ttaagactgc gtcccatttt tatattttct cctttaaatg ttgtaccaca
     9121 gcggcttgca ctcctatgga gcgctaccga gctggcggat ttactagttg cttaagcgac
     9181 tagtttaata ttatttctcg ttgcgacgac gaacgataag tttgtcagat ttcgctttct
     9241 tgttacgagt tttaagacca agagcaggtt tgccccatgg agtagatggt gctttacgac
     9301 caactggtgc tttaccttca ccaccaccgt gtgggtgatc gttagggttc attacagaac
     9361 cacgaactgt tgggcggata cctttccaac ggctacgtcc tgctttacca aggtttacaa
     9421 gtccatgttg ttcgtttccg acaacaccaa ctgtagcacg gcaagttcca agaatcatac
     9481 gaacttcacc tgattgaaga cgaacaagaa catatttacc ttcagaaccc aatacttgag
     9541 cagatgcacc agcagcacgt accaattcac caccacgacc tggtttcaac tcgatgttgt
     9601 gaatcaaagt accaactggg atgttagcaa gtggaagagc gtttccgact ttgatatctg
     9661 cttctggacc tgaaacgata cgttgaccta cttcaagacc ttttggagcg atgatgtatg
     9721 ctttcacacc gtcagtgtag tgtacaagag cgatgtttgc agaacggttt ggatcgtact
     9781 cgattgtttt aacaactgct tcaacgttgt ctttattacg tttgaagtca accaaacggt
     9841 aaaaacgttt gtgtccacca ccttggtgac gaactgtgat acgaccgttg ttgttacgac
     9901 cagccttgct cttcaatgca acaagcaatg atttttcagg agtgcttgtt gtgatttcag
     9961 cgaaatccaa agaagtcata ttacggcgac cgtttgttgt tggtttataa acacgaattc
    10021 ccacgatatt tcctccttag attattcagc ttcagcagca aacaactcga ttgctttaga
    10081 atcagctgta agtgtgatga tagctttttt agttttgtta gtaaaaccag tgtaacgtcc
    10141 aacacgttta gcttttggtt ttacgttgat tgtgttaaca ttggcaactt taacaccttc
    10201 gaaagcagct tcaacagctt gcttgatcaa aagtttgtgt gcacgagtgt caacttcaaa
    10261 tacatatttt cctgcttcaa gttgagccat tgagctttca gtgatgacag gttttttgat
    10321 aacatcatac aaattcatta tgcaagaacc tcctcgattt tagagatagc tgcttgtgtg
    10381 acaagaagtt tgtcgctatt tgcgatgtca agaacacttg cagttgtagc agttgcaact
    10441 ttcacgtttg gaaggttacg agctgaaaga gctgcgaatt catttccttc ttcaaggata
    10501 acaagaactt tagaatcgat gctcaatgct gcaagaactt ttgcaaattc agcagttttt
    10561 ggagctgtaa atgaaagagc gtctacagct acgaatttgt tttcagcaac tttttcagag
    10621 taaactgatt taagagctag gcgacgaact ttttgtggaa gtttgtagcc gtatgaacgt
    10681 ggagttggtc cgaagacaac accaccacca cgccattgtg gtgagcggat agaaccttga
    10741 cgagcacgtc cagttccttt ttgacgccat ggtttgcgtc caccacctga tactgcagag
    10801 cggtttttaa cagcgtgtgt tccttgacga aggcttgcgc gttggctgat gattacatca
    10861 aacacaactg attcatttgg ttcgatacca aatactgcat cgctaagaac aacttggcca
    10921 gcttctttac cagtttggtc aaataatgtt acgtttgcca ttgtgactga tttccccttt
    10981 ctttattatt taccagcttt aactgctgat ttgatagtga taagagattt cttagcacct
    11041 ggtacgttac ctttgataag gataacgttc ttttctggaa caacttgtac aacttcaagg
    11101 ttttgaattg ttacgcggtc gccacccata cgccctgcaa ggtttttacc tttgaatacg
    11161 cggttaggtg caacaggtcc catagaacct ggacgacggt ggtaacgaga accgtgagcc
    11221 attggtccac gtgattgtcc gtggcgtttg ataacacctt ggaaaccttt acctttagaa
    11281 gtaccagtta cgtcaacaac gtctccagct gcgaatgttt caactgtaat ttcagcacca
    11341 acttccaagc cttcaacgtt tttgaattca cgaatgaagc gcttaggagc cgtgttagct
    11401 ttcgctacat gtcctttagc aggtttgttg ctcaatactt cgcgtttgtc atcgaaacca
    11461 acttggatag cgttgtatcc gtctgtttca acagttttaa cttgaagaac aacgtttgga
    11521 gttgcttcaa taactgttac agggatcaat tcgccagctt cagtgaagat ttgagtcatt
    11581 cccacttttt tccctaagat tccttttgtc atgagaaaat agttcctttt ctatattttt
    11641 attcaaaaag tttttaacga gcgtttttta tgctcaagtc taagatacaa agggcgtcaa
    11701 actcaacgtg aaaataggaa actgacacag tgtctagcag acgcgaggaa gtttatcttt
    11761 ttcacaccga gtttagcccg tgttcaatta gattgaaaca ccagcctctg ctcttttata
    11821 ttttagatta aagtttgatt tctacgttta caccacttgg aagatccaat ttcatcaagg
    11881 catcaactgt tttttgagtt gggttaacga tatcgatcaa acgtttgtgt gtacgcattt
    11941 caaattgttc gcgagagtct ttgtatttgt gagtcgcacg aatgattgtg tagaggctac
    12001 gttcagttgg aagtgggatt ggacccgcaa cttgtgcacc tgtacgagta gctgattcta
    12061 cgatttttgc agccgctgtg tcaagcgtac ggtgttcgta agctttcaaa cggatacgga
    12121 tttttttgtt tgccatcttt ttctcctttt cgtctattta agataatagg ctagctccac
    12181 aagaaaaccg acgcggtgtt gcgtggcaat gcaaccgagc gtgtcgcaac ctcttgcatc
    12241 aaaactaagg ctgtaattta cagcaccata atagaataac acaaatcccc tgcgattgca
    12301 agggatttgt taggtttttt cgtttttttg ggatgaaact gttttcctac tttttctttc
    12361 taaaattagg gattttcttc tatatttctt ctatacataa gttaagtcct cttgacatca
    12421 aatttatctt ctgattggtc cactaagata tccgccttag actcagtttc tttatagtat
    12481 cgcagatact gctcccgtct catctgatgg ctagccaata taaaggatgc atcgcgattt
    12541 ctcacagtcg tatctctagc aaggcgtcgc tttaattcgg tctcctcatc cgtgtagaaa
    12601 cagatggttt tttcaaagag ttccttgggt agaaagccaa cagacatccc ttcgacaatc
    12661 aaaattggtt tggctccaga caagacctca ctagccttcc aaggttcttc aattgtcaag
    12721 acatccatac ccgcctgcaa ggcaaggata tctctctgca aactctccag ttcatgcgcc
    12781 actggcagac tggctgtcac cttttgattc ggcgcgtcct tgggtactac caaatagcgt
    12841 ccggaggtga tatagggatc tgtttctagc aaatttactg tagtagaatc taaagcttgg
    12901 tacaattcct gtgcaaaggt tgatttacct gaagctccat gaccgtatat tcccagtgtc
    12961 ctgactttcc ccgtctcgat ctctgagact agttggtcta ctaagtcttt tttcttcatt
    13021 ctctcttcac ctgttcatag atttcttttc cgtcattgag cttgtcccaa atcactactt
    13081 gcccactttt gagcgatttt tgcacatcga taattcgttg gttagacgaa cctcgaaact
    13141 ggagcataag atttctctta gttcgatcat atcttccatc gacaagaatg tcaatcagtg
    13201 acaagagttc cagtttatct ggagtttcca acatcatttc ttcccaagtg tagcccgtcc
    13261 aggaccagat gtccttgtct ggcaattcct tccgaatccg cttaacaagt ggcaagagaa
    13321 tcccagtatt aagaaaaggc tcccctccta gtaaggttaa cccctgaaca taaggctggg
    13381 caagatctgc cataatctgt tcttccaact cagctgtata gggaatgcct gcattgaagg
    13441 accaggtcgc tacattataa cacccctcgc agtgaaacat acagcctgct acatagagag
    13501 agttacgcac gccttcgcca tcaacaaagt taaaggcctt gtagtcaatg atacgacctt
    13561 gactaagttc ctcgcttttc cattcttgtg gttttggatt attcattcgc tacctctatc
    13621 caataacgct cgactccatt gcgagcatcc tcaaatattc caccatttgc tagaatgact
    13681 gctctgctag caggattatt cacgctacag gtcaccagag ctttcttgat gttcttttcc
    13741 ttagcaactt gcaagccctg acggagagtc tcttttgcat aacccttgcc tctttcagat
    13801 ggacggatgg agtagccaat gtggccagca taattcagta acccctcatt cagtctcaat
    13861 cgcagattca aaaatcctag agcacaacct gattcaccaa acaatacgaa ctgtatcgat
    13921 ggaacgcgat tttcaggtag ccatattccc atttctttat tacggttacc ttctagccac
    13981 tcctcgtaag aaaaatcctc aacatcccaa aatcctccat catgggctga ttggctcttt
    14041 tcaaactctg tcatcatatc taaaacagct ttcttatccg ctaatcttgg tctgcgtaat
    14101 tccatcctta cctcccacta tgagaaaagc gagagctggc tctcactttt attttttctt
    14161 gttcttgttt aaaaattgtt ctctgaagct aagcaagcgt tctttcttac cagctccacc
    14221 tttagagtgt ttctcgtgat aacgggtcac ttgtgcgcgc cccttatcgt ctagttgata
    14281 ttttcccatt tcatttcttt ctaatttgtt acttgatgcc cagctatttt aatcgttgaa
    14341 ccattcatat gtttgacacg cgcagcgatt tccttgtgac gcccgttgac catcggtctt
    14401 gcttgaggat tacctaggta gccacaagtt cgcttcacca catctactgt tttagggtcg
    14461 ctattgccac agtttggaca agcaaaccct ctctcagttg gttcaaaatc cccttcaaag
    14521 tcacacttgt agcaacggtc aatcggagta ttggtgccta gatagcctac acggtcataa
    14581 gcataatccc agacagcttc caaggccttt ggattttgct gaaggactgg atactcacaa
    14641 taatggatga aaccacctga cgcacctgct tctggataga ctttctcaaa gtccaatttt
    14701 tcaaacggtg ttggattttt acgaacatcg tagtggaaag agttggtgta gtattccttg
    14761 tctgtgatat caggaataga gccaaacttg tctatatcta gtcggcagaa acggtctgtc
    14821 agactttcgg atggtgttga gtagatagag aaatggtagc catattggtc tgaccactct
    14881 tctacacggc gtttcatatc gtgaatgatg tctagcgtga attccttagc atctggatta
    14941 ctttcccagc tgttaccaaa gaaaactgtc gctacttcat acaagccgat atagcccagc
    15001 gaaacggtcg cacgacaatt cttaaagagc tggtcaacac tttcttcttt acctagacga
    15061 tggccaaaag caccgtactg ataaaggata ggagcattcg ctggtgtcgc ctctttagtg
    15121 cgttcgacac ggtaaacaag agcatcttct gcgatattca ttcgctcgtt gaagatttcc
    15181 cagaacttat tcatatcacc ttcagactca agagcaatac gaggcagatt aaccgtcaca
    15241 acacccagat tcatgcgacc tgaattgact tctacaccat tttcatcctt ccatccttgg
    15301 aggaaagaac ggcaacccat aggcaccttg aaggatcctg tcaagtcaac aatcttatcg
    15361 taagataaaa catctggata catccgtttg gttgcacact caagagccaa ctgcttgatg
    15421 tcgtagttgg gagttccttc ctctaaatta aggcctcttt tcagagtgaa aataagttta
    15481 ggaaagatag ccgtacggtg ttctgaacca agacccttga tgcgaatgtt taaaatagct
    15541 ttttgaattt ctcgttcaaa acgactggtt cccagaccaa aacctagcga agtaaaaggt
    15601 gtttgtccat ttgaagtgaa gagagtattg atttcatact caagagattg catggcatcg
    15661 tagatgtcct tttgcgtttt cttccaagcg taatcttccc gtttttcagg caatacccac
    15721 tcttctgcat ctttgagatg tttttgatag ttcttctctg cataaggcgc caaaatttca
    15781 tcgatacggt cagctgaaca gccaccgtac tggctagaag caacgttggc aatgatttga
    15841 gaaatctgtg ctgtcgcagt ctggatagac ttgggactct ctacctctgc atttccaatc
    15901 ttaaaaccat tttccaacat acccttaaaa tcaatcaaac agcagttggt cataggggta
    15961 tagggactgt agtccaaatc gtgatagtgg atatccccct tttggtgggc attggctacg
    16021 tgcttaggaa gcatttgcag tccgattgat ttcccaacaa tccctgctgt caaatcacgc
    16081 tgagtgttaa agacatcact gtctttatta gcattttcat tgacaactgt ctggtctttg
    16141 ttgagaagtt tatgaatact aaagttgata tccgtcgctt ttgagcgctc aaaatccctc
    16201 tgtgtccgat aagtaatata ctcctcagcc agcgcatatt ctttggcttc aaggagttca
    16261 tgttctacga tattttgaat ttcgtaaatc ttaattccct gtggaaagcg actatgaatt
    16321 tctgtaataa ttctctcagt cagatcattg aggcgttttt caaccagggg tgtcacatcc
    16381 ataaccttgt cagctgcctt gtggagagcc ttgtcaatct tgtccacatc aaatacaaca
    16441 cgtctcccat ctcgtttctc gacgaagaga gttggcaaaa ttgtaatttt ttcttctagt
    16501 gcaatcatat gcatgctctt ttctaaaatg ttctttctaa aaagtattat accactctaa
    16561 aaagaaaaat caatatcttg tgttaaaaat cctaaaattt ttaaaaatac acaagatatt
    16621 gatttggtta tttaatttta tagactttaa actctgagta atcagtcttt acttgttggt
    16681 aattttcttt taaaagtgtt tccacttcag accagactac caccttgtca tttaccacaa
    16741 tcaccttagg ttgtttttct ttcaagtcat taagtaactt attacgattt tcctcagttg
    16801 ctgtatagtg caacggggac aaaatcgccg atggcgacaa gcgctcactc ttacgataaa
    16861 gagtcgcagt atcatcccat gcatagatag catcttccgt atttgtctcc tcttttacca
    16921 aatcagcaag acgattacgt tcttgataag gtactggata aaggacaaac ttcatcaaaa
    16981 aaggaacaga caaaagatag acaaacccaa aaactagcag atatagattt cctttgaaga
    17041 aacgactcca taggctaact ggcgtttctc ttcggcttct tctagcacta cgccccctct
    17101 gttgactctt gatattggtt accaataaaa gtaggaaaac agggaagacg accatcaaat
    17161 aagaagcgtg cagaggctct tgtgaaaaga aaagtaaaat caaacctaaa attaccacaa
    17221 gacttgcagg aaccgaaatg acgtatagtt taaagggttt ggattgaaag agacctaaaa
    17281 agatacaaac cacaaatccc aaaccaaggg acaacaagcc ataaaaaaac atattctcta
    17341 aaattttaga agtaaaatca aagcgaatac tgtcaatagg ataacgaata ccactaatcg
    17401 catccccaaa acttcctgtt gcagcactat agtaggcagt tggataaaag acaagtgaaa
    17461 aacctaaagc cactgcaaga aactgataaa acccatgcgc aaagcgtcta tgcccaaggt
    17521 taaagaccaa caagcctaaa ctcactacag caataaacag gagtgatgat aagggagcaa
    17581 agaaaaatcc gcctgccaaa gctaacccaa tccgtacaaa tcccttatca tggcttggat
    17641 tgcttaggta agccgcaact aaactaaagg ctgcgaataa gaaaggaagc gctaaaagag
    17701 tcgcatagcc tccaccaaaa gcaagacctg taactagcat gtaaaaaata gtcaccagat
    17761 gtccagcttg gtctccttgc tctgtcaagg tgtccgctga tctaaaaagg aaaaatcctc
    17821 ctgctaccaa ggctaaccac tcaaagatgg caaagaaaaa tccgccctga ctcacgtaag
    17881 tcagcaaata ataaagcaaa ccttgacttc cataatagtc gctgtaaatc ttccctgtct
    17941 gatgaagcgc ccaacctgca taaaaatcct gcacttcttg tgcactcatt aagtcgagta
    18001 atagcggtac tcctagagtt atccccgtta caagcgtact ccatagtaaa attttcacca
    18061 aaggaagacg acttgattca cgatgatgcg attcttgctc gatttggtat tctagaggtt
    18121 cacgattctc cttatgaact tcttctactc taccatacac actcatatcg tttctcctgt
    18181 tcaatttatc tgtcttagta tatcaaaaag tcctaggatt gtcagcttgc gatggctgtt
    18241 tgagtgattt tttgcatagt ttcacaaagg tttcaatttc ccgaaagcgg tgtaaatgtg
    18301 tctgtttgaa ctcaatcata tcattcactt cttccttagt tagcatgaat tcccctcctc
    18361 tttctttcta ttcgtaaaag acaagaaaaa taggtcgggt ttgtatccta agttctagat
    18421 ttcttataag ataggggcga atagctgggc gatttctttt acaagctttt gataccagct
    18481 cgttttgata gaatgaggat agacttcctg agaatctgca aatatatttc gaaaatctcg
    18541 ggcgatttcc cttatagaag gagttttata gagtaagact gcattttcat aatggtgtac
    18601 caagctccgg tagtcgagat tgattgtccc caccaccgca aaatcttcgt ctaccaacat
    18661 ctgcttacta tgaataaaac ctggactata ctcataaatc cgaacaccag cagaaagaag
    18721 gtcgggataa gctcctctcg tgactaactg aatgaacttc ttatctggta tgtaaggggt
    18781 gataattcga acatcgaccc ctctcatagc tgcatttttg attgtctctg ttaaatcata
    18841 atctataatc aaataaggtg tcgtaatata gaccgattcc gttgcttgat tgattaaact
    18901 ctgataaact tttttcccta cctgcgctcg aaaaattggc ttgggtccac ttccgtatgg
    18961 aatggttaaa ccgtcactcg ggatagaatg attttctaaa tgatattgat caaaatcact
    19021 aatttctcct cgattaatgt accaagtggt caaaaataag cgtgtcaggg cttttactgc
    19081 tagtccgtct aagcgaattc cactatcctt ccaataacca aatctctcga cgtggttaat
    19141 gtactcatct gccagattga ccccaccagt ataggctatc tgaccatcaa caatcaatat
    19201 ttttctatga tctctgttat tataagccac tgtcaaacga ggaataactt tattgaattt
    19261 atgggcctcg atgcccagct gacgaagtcg atgtgcataa tctcctgtta aagtagccat
    19321 acagccgata tcatcataga gcatcttaac ctctacaccc tgagctacct tttgctctag
    19381 tatatctagt atgcgattcc acatcaaacc ttcttctata atgtaatatt ccaagaaaat
    19441 aaatttctca gcctttttaa gatcttctac catctttttc cacatagctt ctccgttagg
    19501 aaaaaatgta gaggcagttt gatcatagat gtcagcattg gtatccatac tcaataagga
    19561 cttgatgact ccataagctg ccttgtcact ttcttttaat ttctctttta gtagctggct
    19621 atttgcttct tggaaatgca tagagcctag cttcttcagt tgtttgattt cttttttgga
    19681 caatcgcctt tcaccaaaca tcagatagag taagggacca aatactggca caaaggctac
    19741 taacaaccag gttaccttat tctcaggagt cgtattacgg ttgactatcg aaatgattgt
    19801 gatgatactc agtagaatga ggacagtaat ccataaaatg ggagccatgc gtcctaaata
    19861 aagaaagaga ccaaaaacaa gacaaagttc aagtagcata atcgaaagac taaagccata
    19921 cttggacatc aataattgaa atttcctata tttcatatcc cctccttgat agtttgaatg
    19981 ctaaaaacaa gtaattgata ctagtataac gcaggtattc ggtagaaggc aagtatttat
    20041 gattattttc taggtaaaag taaaaaggct gaaaaatcca gccctttcta cttgcatagt
    20101 cttatttagt taaaacgatt tggtccgatg ggtctctatc catatcatct acgacgattt
    20161 gattaccgtt tacagtgtaa attttgacat catcgccaat aatcatgcgt tgatttgctg
    20221 aatcaaatgt aacctgtttg actttctgat ccccgtcaga ttcgagctca gtccatgtac
    20281 cagtcgttcc agttaccact aaagtgatac ggtctccgtc atcctgacca gtataagtcc
    20341 catcaatatc ggtcggttga gcaacaggtt ggttttgtac tggagccgct tgattttggt
    20401 tacctcctgc atttgcagta ttggtattct gttgagcagg ttgttgagca ggctgttgga
    20461 cctgctgctg agcaacaggc tgttgaacct gttgagctct ttgtgaacaa gctactaaga
    20521 gactaaaact tgctagagaa gcaagagaaa gtgtgaatct ttttaatttc atgatgaatt
    20581 tcctttctgc taccaattta gagaaatttt ctctaaccag caattcccct agtataacaa
    20641 gttcaaacaa gggggtcaat ttatctgctc acggtccagc aggtagcccc gtacttctga
    20701 gataaaatag agagaccctg taacgaacag caagtcttga gcgtctgccc tttcttcgaa
    20761 actgctgata aattctcggc aagaagaaac tatatcgtaa cctgtcacat ccctttcgtc
    20821 caaagccccc tgatagtcaa agccggtcac cttgagttcc acctgaggca atttttcagt
    20881 caggtaacct aacatccctt gataatcctt ccgtttcaag gctccaaaaa ggatttgagg
    20941 tcgatagcct tcctgctctt tttctttgat aaactcaacc aagcgagtca aggcagggag
    21001 gttatgagca ccatccaagt aaatctgtgg gcgaatacgc tccaagcgac cagcccaatg
    21061 ggtctgttcc aaggcctttc ttacagcctg ttcatcaaca gcttcctttc cttctcccat
    21121 aaaaagaaga aaagtttgca acgccaaggc tgcattctcc tgctgataga ctccttctaa
    21181 gcctatgttc agctgtgaaa aatttagtaa agagcttgaa aaatcaccat tcagcattaa
    21241 aaaatcttga cctgcctgat aaaggttaac agctaaagat tcggcttttt tctgacagac
    21301 aagcctagct tctggaggca atttcgcaat cactgccttc ttaccagcct tgaaaatacc
    21361 agctttctgc tctgcaattg cttctagact atcacccaag gtttcttgat ggtcaagccc
    21421 aatggaggtg atgacagcaa gctctccagt taccacattg gtcgtgtcaa gtaagccacc
    21481 aattcccact tctaataaaa ccaaatccac ctcttgctcc ctaaaataaa gaaaagcaac
    21541 caaggtcagc atttcaaaaa aggacaactg gtcaggagtt tgcagaagcg ttttctccat
    21601 ctccttgacc tgatcagcca aacggataaa gtctgcgtct gctataggtt gcccattaat
    21661 gcagattcgg tcattgatag agacgatatg aggggaggta aaggtcgcaa cttttttgcc
    21721 atgccccata aataattccc tcataaaagc aatggtagat cctttcccat tagtccctgt
    21781 tacgtggata atagggtaag actgctcagg atttcctaac aaatccaccg cttgctgtat
    21841 tcggcccaaa cctgatcgaa aattcaaacc aatccgacta tgaagccatt cttctacttc
    21901 aaacatacac atctccttga caaaagtcca atcaattatc gcattaaagt atggttacta
    21961 ataaaaacaa ggccaggatt ttcgtcccga cctcttacct ggttagctaa taactagcca
    22021 ctatgaatgt gaatatgggc taaaaacatc cactagatgt tccaactctt ccccatttct
    22081 gggagttggg ctgatacagt ctcccagact gtatcactcc tccataaagc tgttgaagac
    22141 ttcttcaatc atgttccatt cgtcttctga gtcttctggg attggttgca attcgccttc
    22201 tgttccatct tcattttcaa tgaatgagta agcttggatt tcaacttgtc cgtcttcgtc
    22261 ttcttctgcg ttaactggta ctagaagaac atagttttta ccaaattctt cttttccatc
    22321 aattgtcaaa aggatttcaa acaaggtttc atttccttgc tcatctacta gtgtgattag
    22381 ttcacgttct tcgtggtcgt ggttatgatc gtgtgacata gcctctcctt tatattaaaa
    22441 ttttctatct aaataatttt gtaaaatcag ctgagctgct aacttatcaa tgactttctt
    22501 gcgcttattg cgactgatat ctgcttgttc aatcaacatg cgctcagcag ccactgttgt
    22561 caagcgttca tcctgatagt ctaatggtaa accaaaaaac tcttctagct ttgctccgta
    22621 ggcttgacta gcttctacgc gcggtccact tgtattgttc atgtttttag gcaagcccac
    22681 tacaaatcgt tccaccttgt aagtatcaac caattcctta acgcggtcaa aaccaaattg
    22741 gccttgttct tcatttatct ggatgatttc aagcccttga gctgtaaaac caagcggatc
    22801 gctaatcgcc acccctaccg tttttgaacc gacgtccaat cccataattc tcataggtta
    22861 tagatcgact ccttgtcctt tgaggtagta gcgaaccaat tcctcaacga tttcatcacg
    22921 ctcatactta cggatttgat ttcgtgcatt attataacga ggaacgtagg cagggtctcc
    22981 actcaatacg taacctacga tttggttaat tgggttgtaa cccttatcgt tcaacgaagc
    23041 ataaacatct gtcaaagttt cgctaatttc ttttttattg gaatcgtcca atttaaaacg
    23101 tactgtttct tcagtaaatc ccattctaac accctctttc cttagaatag taccattata
    23161 gcataattcc ttaccttcta caattcaggc agtctattta tttggatttt ctattgttct
    23221 gtcgcgccat ttgccaatct atctgaaata tatttgcttg gttcattttt caaaagattt
    23281 tccaaaccaa tattcttcag atgttccaac tgggaagcct tcttgacatc cagaacttga
    23341 aaatcaaaac tagtcgttgt ttgaagttcc gttgcgctca atagttttgt ttcaagtttg
    23401 aaacctgcca atttacgagc ttcaatgata gacttatcct tctcctccgc ttcaagaaga
    23461 gctttttgag tttcctccac tccatgttgg tcaatataag tcttcaactc atcagagact
    23521 ggacgttttt gttggatagt tagactcaaa aaagtcttgt ccttgtatgt aatggtttgt
    23581 gtctgctggc taccatcatc tgacttgggc aagaccaaag tcttagttac aactgtattc
    23641 ttctcagcat tttcaataac tggcaatgcc gactgaagcg tatctttttc tgtttttgta
    23701 gctggtccag tttctttttt ctgtccgcaa ccaaccagga caaaaaggaa agctagacta
    23761 acaagaacta tttttttcat ttctttcttc tttctttttg aaattaaaat agaataagac
    23821 tgggaagtgc tcccagcctt gatgtttata gagctgcacg caaacgtgct tctgcatttt
    23881 ctacattacg gacagagcgt ggtaggaagg cacgaatatc gtcttccttg tagccaactt
    23941 gcaggcgttt ttcatctaca aggattgggc tctttaaaat tctcggtgtt tccataatca
    24001 gattgagaac ttcattgaca ctcaaatctt caatatccac tccaagggct ttggcatagc
    24061 gatttttaga cgaaacgatg ctggctattc cgttatctgt tttggttaga atatccagta
    24121 attcttctct cgtaattcct tctttaccaa ggttttgttc tttataactt aactggtggg
    24181 cattgagcca ggtttttgct tttttacagc tagtacaact tgagactgta taaattttaa
    24241 tcatgtacct acccctttcg ctacatgtta ctatcagttt agtctattat accataaaaa
    24301 acatccgact tgcgacctat ttttaat
//
LOCUS       DAVAZT010000032        23965 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVAZT010000032 DAVAZT010000000
VERSION     DAVAZT010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23965
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.032"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(255..2513)
                     /locus_tag="VQT45_001221"
     CDS             complement(255..2513)
                     /locus_tag="VQT45_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET2359549.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2742..2972)
                     /locus_tag="VQT45_001222"
     CDS             complement(2742..2972)
                     /locus_tag="VQT45_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HET2359550.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3162..3845
                     /locus_tag="VQT45_001223"
     CDS             3162..3845
                     /locus_tag="VQT45_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2359551.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSEIVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3845..4579
                     /locus_tag="VQT45_001224"
     CDS             3845..4579
                     /locus_tag="VQT45_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2359552.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDIAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4733..5590
                     /locus_tag="VQT45_001225"
     CDS             4733..5590
                     /locus_tag="VQT45_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HET2359553.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGYRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5732..6604
                     /locus_tag="VQT45_001226"
     CDS             5732..6604
                     /locus_tag="VQT45_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HET2359554.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLMTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVILLGPGL
                     GDNAFGEDLVKQVFAGLKQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            6886..7569
                     /gene="rpiA"
                     /locus_tag="VQT45_001227"
     CDS             6886..7569
                     /gene="rpiA"
                     /locus_tag="VQT45_001227"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HET2359555.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7583..8794
                     /locus_tag="VQT45_001228"
     CDS             7583..8794
                     /locus_tag="VQT45_001228"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HET2359556.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8796..9338
                     /locus_tag="VQT45_001229"
     CDS             8796..9338
                     /locus_tag="VQT45_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HET2359557.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9354..10163
                     /locus_tag="VQT45_001230"
     CDS             9354..10163
                     /locus_tag="VQT45_001230"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET2359558.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10639..11619
                     /locus_tag="VQT45_001231"
                     /pseudo
     CDS             10639..11619
                     /locus_tag="VQT45_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855254.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
     gene            11644..12156
                     /locus_tag="VQT45_001232"
     CDS             11644..12156
                     /locus_tag="VQT45_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HET2359559.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPISAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            12803..13513
                     /gene="deoD"
                     /locus_tag="VQT45_001233"
     CDS             12803..13513
                     /gene="deoD"
                     /locus_tag="VQT45_001233"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET2359560.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(13536..14060)
                     /locus_tag="VQT45_001234"
     CDS             complement(13536..14060)
                     /locus_tag="VQT45_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HET2359561.1"
                     /translation="MKIAIIGYSGSGKSTIAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(14113..14349)
                     /locus_tag="VQT45_001235"
     CDS             complement(14113..14349)
                     /locus_tag="VQT45_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HET2359562.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(14417..15337)
                     /locus_tag="VQT45_001236"
     CDS             complement(14417..15337)
                     /locus_tag="VQT45_001236"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HET2359563.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            15527..15931
                     /locus_tag="VQT45_001237"
     CDS             15527..15931
                     /locus_tag="VQT45_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359564.1"
                     /translation="MKILKRYILELCFILSFALPFIKGTNADNGRCFVETYYGFTFLM
                     EHAIVTAVFIYSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            16147..16728
                     /locus_tag="VQT45_001238"
     CDS             16147..16728
                     /locus_tag="VQT45_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2359565.1"
                     /translation="MYYAENPDAAHDIHELRVDLLGQKMTFLTDAGVFSKKMVDFGSQ
                     LLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            16725..18002
                     /locus_tag="VQT45_001239"
     CDS             16725..18002
                     /locus_tag="VQT45_001239"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HET2359566.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVHQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            18020..18682
                     /gene="deoC"
                     /locus_tag="VQT45_001240"
     CDS             18020..18682
                     /gene="deoC"
                     /locus_tag="VQT45_001240"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HET2359567.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            18669..19058
                     /locus_tag="VQT45_001241"
     CDS             18669..19058
                     /locus_tag="VQT45_001241"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET2359568.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMAEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            19148..20200
                     /locus_tag="VQT45_001242"
     CDS             19148..20200
                     /locus_tag="VQT45_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HET2359569.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALNNAVKDAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20344..21879
                     /locus_tag="VQT45_001243"
     CDS             20344..21879
                     /locus_tag="VQT45_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2359570.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            21872..22930
                     /locus_tag="VQT45_001244"
     CDS             21872..22930
                     /locus_tag="VQT45_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2359571.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            22933..23889
                     /locus_tag="VQT45_001245"
     CDS             22933..23889
                     /locus_tag="VQT45_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2359572.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
BASE COUNT         6956 a         4329 c         5459 g         7221 t
ORIGIN      
        1 tgcaatacct tttacgaggc tcttttgtcc tgctcttgtt tcaattgact atagcagatt
       61 gaaataagat gagaacaaat cgattgggaa agtaaaatta atttctataa atgttttagc
      121 aattgtttcg tactatttca gattcagtct actatatatc ataatggaca aagggcaagc
      181 tgtcaagaaa ttacagttat tttagtaaaa aaagaagcag aaaaatttaa ttttctactc
      241 cttttctata ggatttattt ttctttttca gaacttttaa cttcagcttt tttggcagat
      301 ttaatctgaa tgtttccctt gctagtcata actgctttga gatctttttc gcttggattt
      361 tcaaggtagt agtcagtgat tgtgtcctca atatagtctt gaatagtccg acgaagtggg
      421 cgtgctccca tttttggatc ataacctagg tcaaccaact tttccttgac cttgtcagtt
      481 acatccaaac gaatgttgtt gctagagagg cgcttgttaa catctgctag catgagctcg
      541 acaatctgaa ggaggttatc cttgctgaga gccttaaatt cgataatgcc atcaaaacgg
      601 ttcataaact ctgggctaaa gaagttaccg agttcaccga ggacagaatt ggtacgtcct
      661 tctctagcag caccaaatcc aacgctagct tcggtctttc ctgtacctgc atttgaggtc
      721 atgataatga tggcatcctt gaagctaacg gtgcgtcctt gcccgtctgt caaacgacca
      781 tcgtccaaga cttgaagaaa catgtgcata acatctgggt gagctttttc cacttcatcg
      841 agaaggatga gagaatatgg attgtggcga actttttcag ttaattgacc agcctcatca
      901 tagccaacat aacctggagg agcgccgacc aacttagcca cactatgttt ttccatgtat
      961 tcactcatat caaagcgaat catactatca gcagaaccaa aaagttcgat agccagttgt
     1021 ttggaaagtt ctgtcttacc gacaccagtt ggcccaacga agaggaagct tccgattggg
     1081 cggttagggg taccaagtcc gacacgatta cggcgaatag ccttggcaat cttatcgact
     1141 gcatcatctt ggccaataac atgagacttg agatcttcgg ctagatggat gagttgagat
     1201 tgttctttct ctttcaaatc accaacaggg atattggttt tctgctcgat aatgtgctca
     1261 atagttttct cgctgatgat aggagtatcc tggtctgtga tctttttctt ttgcatttcc
     1321 ttatacttgg caatctggtc gcggaagtag gccgccttct caaaatcttc ttctcgtgta
     1381 gcttgagact tgagattttc agcctcaatc aagcgctgat caattacttt aggatccaca
     1441 aaattcaagg tcaagttcat cttagaacca gcttcatcta ggaggtcaat ggccttgtca
     1501 ggcaagaagc gatcttggat gtagcgattg gaaagagttg cagctgcttc aatcgcagca
     1561 tctgtatatt gaacgtggtg gtaatcttcg tatttctttt gaatcccttt gagaatagtg
     1621 attgtttcgt ccaccgttgg ttcatcgact ttaacaggct gcatacgacg ctcgagggca
     1681 gcatcctttt caatgatacg gtattcattg agggtagtag caccgactag ttgcagttct
     1741 ccacgagcaa gggctggctt gaggatattt cctgcgtcca tattaccatc actcgcagaa
     1801 ccagcaccaa caatttcatg gatttcatcg ataaagagga tgatgtcttc acgtttgcga
     1861 atttcttcca tgagtttttg catgcgttct tcaaattgtc ctcgaatccc cgttccttga
     1921 actaagctaa ccacatccag acggatgact tgtttacctt ggagtttatg tggcacatcg
     1981 ccatcgacaa ttttctgagc tagaccttcg acaacggccg tttttccgac accaggttca
     2041 ccgataagga caggattatt cttggttcta cgattgagaa tctcgatgac acggataatc
     2101 tcatcgtcgc gcccaataac ggggtcaatg tctccacgac gggcaatttc agttacatta
     2161 ataccaaatt cttccagcag gcctttttct tggctaggtg gcggagtttg agcagatcca
     2221 cgattttggg aaccataacc gccgtttcca ccgtaacctc cacctgattg ggttggggga
     2281 ataggaggag tattgctaga aggtctgaaa ttgtttagat cattgaagaa atcaccaaag
     2341 ggatcgaagt cacgattgtt cagatccgtc atacctttga agaggctatt gttaggatct
     2401 gttttgataa tcttatagca gttttgacag aggtcaattt gtttttgttt tccattgaga
     2461 ttggtgtaaa gatgaattgt tgagtcgtta attttacagt tttgacaaag catacatcta
     2521 cctcatttct ttctttagcc tgacttgttt aaaggtcaaa aatagtcaaa ttctatactc
     2581 tcattataac aggattgggg tgtaaagcaa gtaaaaagat tgaagctttg agaagttgtt
     2641 acaatgaaaa tttttgtgaa tttggactat aaaaaaatcc tatttgtgag acaaaaagga
     2701 ttttacttag acatgcaggg acaatcccag cttgttttag attagtagag aagttcgtaa
     2761 atttccattg cgattaagtc aatgctatca aacgtatacg tttcgcgatc ttctacgtca
     2821 cgaagggtaa agattgggcc gttttcttcg tcgtggctgt acgcaacttc tgcaacaaca
     2881 actccttcgc gttcaaaatt acgttttaaa tttccgccat cgtttgccat tgcttcaagg
     2941 cggttgatga ttctaaccaa atgtgattcc attttgattc tccttcattt cttatcgtta
     3001 ctattttacc ataaaggagg ccaacttgac tagaaaaaac taagatttct cgctaattct
     3061 gctagtttaa agatttttaa ataaattgga taaaaaattt aaattttaat tcaaaacatg
     3121 ttataatcat acagtattct attttagaaa gcagtgtgac tatgaatttt tcttttttac
     3181 ctaagtattt accttatttt aactatgggg ctgttgtgac gattcttatt tctatctgtg
     3241 ttatcttttt gggaactatt ttgggtgttg tcttggcttt tgggcaacgt tcaaagttta
     3301 aaccgcttgt ttggttggcc aacttgtacg tttggatttt ccgtgggaca ccgatgatgg
     3361 ttcaaattat gattgccttt gctcttatgc atatcaatgc tccgactatt cagattggaa
     3421 ttttaggtgt tgatttttcg cgtctgattc cagggatttt gattatctct atgaatagtg
     3481 gtgcttatgt ttcggagatt gttcgtgccg gaatcaatgc ggttccaaaa ggtcagctag
     3541 aggcggctta ttcgctaggg attcgtccta aaaatgcgat gcgttatgtg attttgccac
     3601 aagcagtcaa aaatatcttg ccagcattgg ggaacgaatt tatcaccatt atcaaggaca
     3661 gctccctctt atcagctatt ggggtcatgg agttgtggaa tggggctaca acagtttcta
     3721 caacaaccta tctaccttta acaccacttt tatttgcagc attttactac ttgattatga
     3781 cctctattct gacagtagcc ttgaaagctt ttgaaaaaca tatgggacaa ggagataaga
     3841 aataatgaca gaaaccttga taaaaattga aaatttacat aaatcttttg gaaagaatga
     3901 agtattgaag ggcatcaacc tcgagattaa aagaggagaa gttgtcgtta tcatcggtcc
     3961 ttcagggagt gggaaatcta ccttgcttcg ctctatgaat ttgttggagg aagcaaccaa
     4021 ggggaaggtt atctttgagg gagtcgatat tacggacaag aagaatgacc tgtttgccat
     4081 gcgtgagaag atgggcatgg ttttccaaca atttaacctc tttcctaata tgactgtgat
     4141 ggaaaatatt accttgtcac ctatcaagac taaaggtgaa agcagggaag ttgctgagaa
     4201 gagagcccaa gagcttttgg aaaaagttgg tttgccagat aaggcagacg cttatccaca
     4261 gagtctgtcg ggtgggcaac aacaacggat tgccatcgcg cgtgggttgg ctatggaacc
     4321 agatgttttg ctctttgacg aaccaacttc agccttggat cctgaaatgg taggtgaggt
     4381 attggctgtt atgcaagaca ttgccaagtc agggatgact atggttatcg taacacatga
     4441 gatgggattt gcccgtgagg tggcagatcg tgttatcttt atggcagacg gtgtggttgt
     4501 tgaagatggg acacctgagc agatttttga acaaacccaa gaacaacgga ctaaagattt
     4561 cttgagtaag gttttataat ctattttaaa atttcaagac aagattagtg aaaagttcaa
     4621 ccagagcttt ttcttatagt ttgaaactat aggataacct aggaaagaag tgttagaggg
     4681 cactagcagt ttttggtata atggaagata tttgaaagaa aagagaagtg atatgacaca
     4741 gattattgat gggaaagctt tagcggccaa attgcagggg cagttggctg aaaagactgc
     4801 aaaattaaag gaggaaacag ctctagtgcc tggtttggta gtgattttgg ttggggataa
     4861 tccagccagc caagtctacg ttcgcaacaa ggagaggtca gctcttgcgg ctggttaccg
     4921 tagcgaagta gtgcgagttc cagagaccat tactcaagag gaattgttag acctgattgc
     4981 taaatataat caggatccag cttggcatgg gattttggtc cagttgccat taccaaaaca
     5041 tatcgatgaa gaggcggttt tattagccat tgacccagaa aaggatgtgg atggtttcca
     5101 tcccctaaac atgggacgtc tttggtctgg acatccagtc atgattccct cgacacctgc
     5161 aggaattatg gaaatgtttc atgaatatgg gattgacttg gaaggtaaaa atgcggtcgt
     5221 aatcggtcgt tcaaatatcg ttggaaaacc tatggctcag cttcttttgg ctaaaaatgc
     5281 gacagtaacc ttgacccact cacgaactca taatcttgcc aaggtggctg ctaaagcaga
     5341 tattcttgta gtcgcaatcg gccgcgccaa gtttgtgact gctgactttg tcaaaccagg
     5401 tgcggttgtc attgacgttg ggatgaatcg agatgaaaat gggaagctct gtggagatgt
     5461 tgattatgag gcagttgcac cacttgctag ccatatcacg ccagtccctg gaggtgtcgg
     5521 tcctatgacc attaccatgc tgatggagca aacttatcaa gcagcacttc ggacattgga
     5581 tagaaaataa gagaagcatt cgattaatag agtgtatttt ctatagctat atctaaaatg
     5641 gcagaaatga atattaaatt ttagatataa gattacaaaa ggaggtctgc gtctcctttt
     5701 tattgtataa taaaagtgag aggaaaaaag gatgaaagtg attaatcaaa ccttattaga
     5761 aaaagttatt attgaacgtt ctcgttcaag tcataaagga gattatggtc gtctgctgct
     5821 gcttggtggt acttatcctt atggaggtgc catcatcatg gctgctttag cagctgtaaa
     5881 aagcggtgca ggattgatga ccgttggaac ggacagggaa aatatcccgg ctctgcacag
     5941 ccatttacct gagcctatgg ccttttctct tcaagaccag caattgttaa aagagcaatt
     6001 ggagaaggca gaagttatct tgctggggcc tggtttagga gacaatgctt ttggagaaga
     6061 tttagttaaa caggtctttg ctggcttaaa acagaatcag attttgattg tagacggagg
     6121 tgccttgacc attcttgcta ggacaagttt gtcatttccc tcaagccagc ttatcctaac
     6181 tcctcaccaa aaagaatggg aaaaattatc tggaattacg attgaaaagc aaaaggaaga
     6241 tgcaacggct agtgttctga cttccttccc tcaaggaaca attttggtgg agaaaggccc
     6301 agctactcgt atttgggaag ttggccaatc tgattattac cagttacagg ttggtggtcc
     6361 ttatcaggcg actgggggaa tgggagatac tctggctggg atgatcgcag gatttgtagg
     6421 ccaattccga caggccagtc tctacgagcg tgtggcagta gcgacccatc ttcattcagc
     6481 catagcccaa gaactatctc aagaaaatta tgtggtctta ccgacggaaa tcagcaggta
     6541 tcttcccaaa ataatgaaaa ttatttgtca acaagagagg gtaagcaaag ataaacttgt
     6601 ttaaaataga cagataaatc tacttccttc tcttaattta tgattcttga aatgcgcctg
     6661 ctttaaggct aaactagacg tatcaaagtt aagagtttgt ttttgtaact ggaaagagat
     6721 gaacaaatca aatacataaa agataaactc atttttattc gttttgtaaa aataaaatgc
     6781 atatttttaa agaaagattg atgaaaaatg tagatttgat gtttttactt gaataaaaag
     6841 cggtttcata gtaaaataag aactgagaat gatggaggta aatcggtgga aaatctgaag
     6901 aaaatggcag gtatcaaggc tgctgagttc gtgagcgatg gaatggtcgt tggacttgga
     6961 acaggctcga ctgcctatta ttttgtcgaa gaaatcggtc gtcgtatcaa ggaagaagga
     7021 ttgcagatta cagctgtaac aacttctagt gtgaccacta aacaggcaga aggccttaat
     7081 atcccgctca agtctattga ccaagtagac tttgtcgatg tgacggttga tggcgcggat
     7141 gaagtggata gtcagtttaa tggaatcaaa ggcggtggtg gtgcccttct catggaaaag
     7201 gtggtcgcaa caccatcaaa agaatacatt tgggtggtgg atgaaagcaa gctggtcgaa
     7261 aaactaggtg cttttaaatt gccagtagaa gtggttcagt atggtgcaga gcaggtcttt
     7321 cgtcattttg aacgagctgg ctacaaacca agtttccgtg aaaaagacgg tcaacgtttt
     7381 gtgacggata tgcagaattt tatcattgac ctcgccttgg atgtcattga aaatccaatt
     7441 gcttttggac aagaattgga ccatgtcgtt ggtgttgtgg agcatggttt attcaaccaa
     7501 atggtggata aggtaatcgt tgctggacga gatggagttc agatttcaac ttcaaaaaaa
     7561 ggaaaataga agggggcata agatgtctaa atttaatcgt attcatttgg tggtactgga
     7621 ttctgtagga atcggtgcag caccagatgc taataacttt gtcaatgcag gggttccaga
     7681 tggagcttct gacacactgg gacacatttc aaaaacagtt ggtttgaatg tcccaaacat
     7741 ggctaaaata ggtcttggaa atattcctcg tgaaactcct cttaagactg tagcagctga
     7801 aagcaatcca actggatatg caacaaaatt agaggaagta tctcttggta aggatactat
     7861 gactggacac tgggaaatca tgggactcaa cattactgag cctttcgata ctttctggaa
     7921 cggattccca gaagaaatcc tgacaaaaat cgaagaattc tcaggacgca aggttattcg
     7981 tgaagccaac aaaccttatt caggaacggc tgttatcgat gattttggac cacgtcagat
     8041 ggaaactgga gagttgatta tctatacttc agctgaccct gttttgcaga ttgctgccca
     8101 cgaagacatt attcctttgg atgaattgta ccgtatctgt gaatacgctc gttcgattac
     8161 ccttgagcgt cctgcccttc ttggtcgcat cattgctcgc ccttatgtag gtgaaccagg
     8221 taacttcact cgtacggcaa accgtcgtga cttggctgta tctccatttt ccccaactgt
     8281 tttggataaa ttgaatgagg ctggtatcga tacttatgct gtgggtaaaa tcaacgatat
     8341 ctttaacggt gctggtatca accatgacat gggtcacaac aagtcaaata gtcatggaat
     8401 tgatacacta ttgaagacta tgggacttgc tgagtttgaa aaaggattct cattcacaaa
     8461 cctagttgac tttgatgccc tttacggcca tcgtcgtaat gctcacggtt accgtgattg
     8521 cttgcatgag tttgatgaac gcttacctga aattatcgca gctatgagag agaatgacct
     8581 tctcttgatt actgcggacc atggaaatga cccaacgtat gcaggaacgg atcacactcg
     8641 ggaatatatt ccattgttgg cctatagccc tgcctttaaa ggaaatggtc tcattccagt
     8701 aggacatttt gcagatattt cagcgactgt tgccgataac tttggtgtgg aaactgctat
     8761 gattggggaa agtttcttag ataaattggt ataagatgac gcgctatgct ttgctggtga
     8821 gaggtatcaa tgttggtggt aagaataagg tcgtcatggc ggagcttcgt caagaattga
     8881 caaacttggg actggaaaag gttgagagct acatcaatag tggcaatatt ttctttactt
     8941 cgatagattc caaagcccaa ttggttgaaa agctagagac tttctttgca gtccattatc
     9001 catttattca gagcttttct ttactgagtc tagaggactt tgaggcggaa cttgaaaatc
     9061 taccagcttg gtggagcaga gacttggcac gaaaagattt tctcttttac actgagggtt
     9121 tggatgtgga ccaagtcatc gcgacagttg aaagtttaga gctgaaagat gaagtgcttt
     9181 attttggaaa acttgggatt ttctggggga aattttctga agaatcctat tctaagactg
     9241 cctatcataa gtacttgctg aaggtgcctt tctaccgcca cattactatt cgtaatgcta
     9301 aaacctttga caaaattggt caaatgctaa aaaaataata aaggagacac acaatgacat
     9361 ttttaaacaa aatccatgaa actgctactt tcctgaaaga aaagggaatt gcagcccctg
     9421 agttcggtct aatccttgga tcaggacttg gagaattggc agaagaaatc gaaaatccag
     9481 ttgtagtaga ctatgctgag attccaaact ggggccgttc aacagtagtc ggtcatgctg
     9541 gtaaattggt atatggtgaa ctggcaggtc gcaaggtctt ggctcttcaa gggcgtttcc
     9601 atttctatga agggaatcct ctggaagtgg tgactttccc agttcgtgtg atgaaagttc
     9661 ttggatgtga aggtgttatt gtaaccaatg cagctggcgg tatcggattt ggtcctggta
     9721 ccttgatggc tatctcagac catatcaaca tgacggggca aaatccattg atgggtgaaa
     9781 acttggatga ctttggccca cgtttcccag atatgtctag ggcctacaca ccagaatacc
     9841 gtgccactgc ccatgaagtg gctaaaaaac ttaatatcaa gcttgatgaa ggtgtctata
     9901 tcggagttac tggtccgact tatgaaacac cagcagaaat tcgttcctat aagacactgg
     9961 gagcagatgc agttggtatg tctacggttc ctgaagttat cgtggcagcc cactctggct
    10021 tgaaagttct gggaatttca tgtatcacta actttgcggc cggtttccaa gaagaactca
    10081 atcacgaaga agttgtagaa gtgactgaac gtgttaaagg tgatttcaaa ggcttgctta
    10141 aagcgattct tgctgaattg taagaaaaaa gatttaaaag ggggagtgcc tctgtttttt
    10201 caggattgac tgcctatccg gattaaagaa gaaacagagg aatactatga gcttcttcct
    10261 gctcttataa ctgaaagaag cggaagaata ggtatgtctg atctgatagc cagcattgtg
    10321 aaagacaaga ttctaggata ctagcattag cttcctagcc aagcagacta gtatgataag
    10381 gagagatgag aatgaattga ctttctgaat ttctcagtct tatcatatat agcacaatga
    10441 gatttcgctt gagtctgctt gtaaataaac gaaaagaaag ataagaaata atgaaaattg
    10501 gtcaacgaat tatgcgcttt ggcataaaaa attaagtatc ggagttgtat ctgttgtagt
    10561 cggctttgat ttctagctcc agctggaatt tcagccaatg aagtaaagca agatgtaaca
    10621 tctgaagtgg taataggtgt gctagattct aaggaggaat tgaaagagtc agaaaatgat
    10681 gctccaaaac tagaaactcc tcttagagag gagccaagac tagctcctca aacgcttccg
    10741 gaagcaagtg aagttcttga aaacaaaagg gaagagtcaa aagtagagat aacataacca
    10801 gctcaagcgg atgatatccg caaggttgtt ggggaattag ccaaggatat aagtattact
    10861 aagttgtata tgacaggtca ttctcttgga tgttacctag ctcagattgc agcggttgaa
    10921 gcttaccaaa aatatcctga tttttataac catgtattga ggaaagtgac aactttcagt
    10981 gctcctaaag tgattacttc cagaactgtt tggaatgcta agaatggttt ctgggatgtt
    11041 ggtttggaaa gtcgtaaatt agctgttagt ggaaaaatta agcattatgt ggttgataat
    11101 gacaatgttg tgactccctt gattcataat aatcgtgata ttgttacatt tacaggtaat
    11161 tcacgcttta aacaccgttc tcgtggctat tttgaaagtc caatgaatga tattcctaac
    11221 tttaatattg gtaaacaagc taccttggat aaacatggtt atcgtgatcc gaaattggat
    11281 aaagtgcgat tctttaagaa acaggctctg cctcgatctt ctagtcaacc aagcgctgaa
    11341 ccaatggaaa atattgcctt aggaaaacag gttactcaaa gttcgacagc tttcggagga
    11401 gatgctagaa gagctgtgga tggcaaagtc gatggtaact atggtcacaa ttctgtcact
    11461 catacaaact tccaatctaa gccttggtgg caagtagatt tggctaaaga agaaaccatt
    11521 cgccaaatca atatttacaa ccgaacagac actgcccagg atagattggc aaactttgat
    11581 gtcattcttt tagacagttc tggtaaagaa attgagtgaa aacgtataat atctcctaaa
    11641 gatgtgtcag cacaaattac gattaaccat aaaaaagcgc gctatgttcg gattgagcta
    11701 gaaggctata atgccctcag tcttgcagaa gttgaagttt tccgctttat agctacgaat
    11761 gctgaaacgg cgacacaagt ttctaagcca gttcaaccaa tcagtcagac tcctgtgaaa
    11821 gataaaacat tgacaattca acacagtgga gcttacattg cccgctactc cataacttgg
    11881 gaagaagttc cagtagataa agatggaaac caagttgttc gtagtcattc ttgggaagga
    11941 aacggtcgca accagactgc gggttttgtc ctcaacctcc caatcaaaga aaatatgaga
    12001 aatctgcgag ttaagattga gaaaaagacg ggcctactat ggaatagatg gcaaacaatc
    12061 tatgaaaaca gaccaatttc agctcaaccc caccgtaaaa ttacccattg gggtacgaca
    12121 ttgaattcca aggtgagtga cgatgatgtc ttgtaatctg atggtacaat gacagttagt
    12181 ttgtctagtt tataagaaag tactacctga gcttgaatag aactcaggta gctctctgtg
    12241 aaagaacaaa attaatactc aatgaaaatc aaagagcaaa ctaggaaact agccgcaggt
    12301 tgctcaaagc actgctttga ggttgtagat aagactgacg aagtcagtca catatataat
    12361 ccaaggcgac gttgacgtgg tttgaagaga ttttcgaaga gtataaacag aaaggtagag
    12421 cgcgtgttct aatttgaaca cgagtagaaa acttttctaa aaacaaaaac gaaaggatgg
    12481 gtaaactgta ttcgctgaac tgaatacggg cgactctcct ctaaatcaaa attaagaaag
    12541 gaattgaccc caccctaaaa gtagtgggaa aaagatagtt ggtctagcga gcatcgctca
    12601 ctgcgcccaa ctcctatttt cccttcgctt tttgatgggt ttggtatctt tctcaatata
    12661 aaataaagaa aggtagagcg tgtgttttga tttgaacacg agcggaaaac tcggaaaata
    12721 gataatctga ctgaaaaatc aggatttctc gtcaggttcc taattttcag tcgttttctt
    12781 ctcgctcttt gtatcataaa ttatgtctat ccatattgct gctcagcagg gtgaaattgc
    12841 tgataaaatt cttcttcctg gggatcctct tcgtgctaag tttattgcgg agaatttcct
    12901 tgatgatgct gtttgtttta acgaagtgcg taacatgttt ggttacactg gtacttacaa
    12961 gggtcactgt gtatctgtca tgggaactgg gatgggaatg ccatctattt cgatttatgc
    13021 gcgtgagtta atcgtagact acggtgtgaa gaaattgatt cgtgtgggaa ctgcaggttc
    13081 tttgaatgaa gaggttcatg ttcgtgaatt agttttggcg caggcggctg caaccaactc
    13141 aaacatcgtt cgtaatgact ggccacagta cgattttcca caaattgcta gctttgattt
    13201 gcttgataaa gcctaccata tcgccaaaaa acttggtatg actactcacg ttgggaacgt
    13261 tttgtcatct gatgtctttt actcaaatta ctttgaaaag aatatcgagc ttggtaaatg
    13321 gggagtcaag gctgtggaaa tggaagcagc agctctttac tatcttgctg cccaatacca
    13381 tgttgatgcg ctagctatca tgaccatctc tgatagcttg gtcaatccag acgaagacac
    13441 aactgcagaa gaacgtcaaa ataccttcac tgatatgatg aaggttggtt tggaaacctt
    13501 gattgcagaa taattatagc caaaaaggaa gccctttatg aattgtagga cttccttttc
    13561 ttatccagaa attgatctag ctctctctga tttcgaagaa tagtgacttt atgtgaatat
    13621 tcttggcaaa gtttttggta attttctttt tgagttttgc tacgcccatc ccaaagaatc
    13681 catctgataa actcccactc aaagcgttca gggcaatctg ccgccatact ttctctgact
    13741 tttccacggt atttaagata acgcttaaag gctctaaaga gacaggtcaa tggcgaaaaa
    13801 ttgagaaaga tgatttggtc agcttcttgc attcgttctt ggtagtagca ccaagaataa
    13861 ttaccatcga tgacccaagc tttatgcttg gtgagaaagt tttttatctc ggttaacatc
    13921 cattcgcagt cactgtcttg ccaaccaggt tgaaattgga gtgtgtccat gtgcagtttt
    13981 ggaatggagt agtagttaga taacttttct gctatagttg acttaccaga accagaatat
    14041 ccgataattg cgattttcat tttctacttt ttcctatttg gagacaaaaa aacagcctct
    14101 atggactgtt tcttatttag caagtttagc tgaaagacga gctttatcgc ggcttgcttt
    14161 gtttttgtga atcaaacctt tagtttctgc tttatcgata gctgagctag cagcacggaa
    14221 aagttcttca gatgggtttg cttcgaaagc ttttatagca gtacgcatag ctgatttttg
    14281 agctgagttc ttttcgtttt gtttaacgtt caattcagcg cgtttgatag ctgatttaat
    14341 gtttgccaat gttcttacct ccatatttac taactatacc attatatatg aaaacttacg
    14401 ttttgacaag ggaaaattac ttttttaagt aaatttcatc gatttcatgg ttcttgcttt
    14461 tatgaagaat cacttctgca cgatttctgg ttggttcaat ataattttgc agatttgtga
    14521 gattgatact gatccagacc tgatgggcaa aggactccac ttccccaatc ggcatctgag
    14581 taaaacgata atagtagcta tcagggtcgt tttgggctag gctcagcatt ttcaagaaac
    14641 ggtccagata ccaactttca atatcatcca ctccagcatc tacatagatg gaaaagtcaa
    14701 agaagtcagt gatatagaga cgatcgtttt gtggattttg aaagacatta attccctcaa
    14761 caattacaaa atcagcagct ttgacacttt gtttcttttc gggtacgatg tcgtaaactt
    14821 catgagaata gacaggaata tctacatctt gtccattttt gatgcggtcc aagaagttga
    14881 gaagagcttc catatcatag ctttcaggaa atcctttacg atttaaaatc ccctgctcaa
    14941 tcaaggtttg attgggatag agaaaaccat cagttgtaac caactcaacc gtagcatctg
    15001 taaacgtacg ggacagtagg atttgaagta ggcgactggt tgtggatttt ccaacggcaa
    15061 cactcccaga aaccccaata ataaaaggtt gagatttact ttcacgttgg aggaaaattc
    15121 cttttgaaaa ggctaaatct tccttagttc gcttgtaaat ctgaatcaga tgagccaagg
    15181 ggagatagat atctgtaacg tcttggagac tgatttggtc attaaaactc ttgatagatt
    15241 ccaattcttc ttctgtcaaa ggaggtgttg tctttcgatg taaagattgc caagtctggc
    15301 ggctgatttt ttcaaaatgt aaaaattcgt tggtcatttg ttttccccta gatattttgt
    15361 ctatcatacc ataaaaagct aaaaaaataa agcggtttct tgaatgtggt aagtcaatgg
    15421 tatatagtat aagtgatcaa tttattgatg aaataggaga tagattctac tgatttataa
    15481 gcttataaag ggggcttttt agttcacaac ttataggagg tgtactatga aaatcttaaa
    15541 acgttacata ttggaactct gttttatttt aagttttgct ttacctttta taaaaggaac
    15601 caatgcagat aatggtagat gctttgtgga aacctattac ggttttactt ttttgatgga
    15661 acatgctatt gtaacagctg tctttatcta ttcgttttta attgctttct tactaaaaaa
    15721 acgatgggcg aaatggattg ctgctggtag ttattgcttt ttagtcctat ggattgcgac
    15781 agagggttat ttcttccgca tgtcactaga agatttgata cgactttgga caagtttgga
    15841 aatcctgaca caaacgtatc agttgggctt ttatctaaac attttgttag gaattttgtt
    15901 gataataaag tattttaagg ttaagcaata gaaataataa tctgcctgat tatagatgat
    15961 aaactttttg tttttatctg gactgtgata tttatagttc taaatggttt attatttata
    16021 agtgttgaaa gagattgaag aaaatggctt cgtgacttgc tttcttcggt ctttttcgtt
    16081 ttattatcaa tttgtaaacg atttacaatt tgagtcaaat tatggtaaaa tagtgtcatg
    16141 agtaaaatgt attatgcaga aaatcctgac gctgctcacg acattcatga gttgagagtg
    16201 gacttgttgg gacaaaaaat gacttttttg acagatgcgg gtgtttttag caagaaaatg
    16261 gttgactttg gaagtcaact cttgctcaag tgtctggatg tcaaccaagg agagacagtc
    16321 ctagatgtag gctgtggtta tggtccatta ggtttgtcct tggtcaaggt ttacggagtt
    16381 caggcgacca tggttgatat taacactcgt gccttggatt tagctcggag aaatgctgaa
    16441 aaaaataatg caaaagcgac gattttccag tccaacatct atgaacaagt tgaaggacat
    16501 tttgatcatg tcatttccaa tcctcctatc cgtgcgggca agcaagtcgt tcatgaaatc
    16561 attgagaaaa gtaaagattt cttggaaact ggtggggatt tgacaatcgt catccagaaa
    16621 aaacaagggg ctccaagtgc taagtccaag atggaggatg tgtttggtaa ttgtgaaatc
    16681 cttaaaaaag acaaaggata ctatatcctt agaagtgtga aagaatgaga gcagttgatt
    16741 taatacaaaa aaaacgagac ggtcaagaac tgacttcaag tgaaattgaa tggctggtag
    16801 aaggctatgt gtcaggaact gttcctgatt atcagatgtc tgcctttgct atggctgttt
    16861 attttaaagg aatgacgact cgtgaaattt ctgatttaac gatgaatatg gttaagactg
    16921 ggcaagagtt tgacctgtca gccattgatg gtgtgaaagt tgacaagcat tctactggtg
    16981 gtgtcggcga taaggtaacc ttgattttag ctcctcttgt tgctagcttc ggtgtgcctg
    17041 tagcaaaaat gagtggtcgt ggtcttggcc atacaggcgg aacaattgat aaattggagt
    17101 ccattagggg ctatcaagta gaacgtagtc aagaggattt tattcgtcag gttcaggata
    17161 ttggagtatc tgtcattggg caatcagacc agctggtcaa agcagataag cttctctatg
    17221 cccttcgtga tgtgaccgca actgtcgaca cgattccttt gattgcgagt tcggtgatga
    17281 gcaagaaaat tgcggcaggg gcggatgcta ttttgctaga cgtgactgtc ggtgagggtg
    17341 ccttcatgaa gacggttgat gaggcgcgtg agttggctca aactatggta gatcttggta
    17401 aggttgttgg acggaagaca gtagcagtga ttacggatat gagccagcct ttgggacgag
    17461 cgattggaaa tcgtctggaa atacttgaag cattggagat tttgcaaggt caaggacgtc
    17521 aggatattac ccactttatt tgtgaattgg ctcaaattat gcttggtttg gcaaatgtta
    17581 acaagactgt tgaagaagtt caccaacatc ttgagaatgg tcaagcactg gctaagtttg
    17641 aggaaatggt gcaagcccaa ggtggagact tggaagacct ctatcgtcct gtaaatgtag
    17701 ctcatgtggt ggaaatccct gctcaggaaa cgggtgtcat ttcagctctt ccagctatgg
    17761 actttggtct ttatgccatg aggctggggg ctggtcgtgc agttaagtct gatgccttgg
    17821 actatgaaac aggaattgtt tttgaaaaga agattggaga ctccgttcaa aagggtgaaa
    17881 ttgttgcaaa agtatacaca aatgaaaaaa ttccacctca actagttaca gatttccaaa
    17941 aatgtgttaa aataagtgat gaagtgaaaa aaatccgtga aattgtagaa atcatctcct
    18001 aaatggaggg aaaaccgaaa tgaaattaaa taaatatata gatcatacgc ttttaaaaca
    18061 agatgcaaag aaaaaacaaa ttgatagttt gttgtctgag gctagagagt atgactttgc
    18121 cagtgtttgc gttaatccga cctgggttga acatgctaaa aaaggacttg aaggcacaga
    18181 tgttaaggtt tgcacggtag taggtttccc tttgggagca acaacttcag ccgtgaaagc
    18241 atttgagaca aaagaagcta tccaaaatgg tgcagatgag attgatatgg tgatcaatgt
    18301 tggagctctc aaatcaggta atttagcctt ggttgagtca gatattcgcg cagtagtgga
    18361 agcaagtggt gataagttag tgaaagtcat tattgaagct tgccttctga cagaccaaga
    18421 aaaaattgtt gtttgccaat tggcccaaaa agctggggct gactttgtta aaacatctac
    18481 tggtttttca actggtggtg ctacgatagc agatgttaca ttaatgcgtg aaacagttgg
    18541 atctgatatg ggagtcaagg ctgctggtgg agctcgttct tatgcagatg ctcttgcctt
    18601 tgtcgaagca ggtgcgaccc gtatcggaac gtcagctggg gtagctattt taaaaggaga
    18661 attggcagat ggcgactact gagttgattg aactggcaat tgaaaccagc aaacatgcct
    18721 atgtccccta ttctcacttt cctatcggag cagttttagt agccaaagac ggaagtgttt
    18781 acacgggagt gaatatcgaa aatgctagct atcctttgac caattgcggt gagagaacag
    18841 ctatttttaa ggctatatct gaaggccaaa gagaattttc agaattgatt gtctatggtc
    18901 aaactgaaaa accgatctcg ccatgtggtg cttgtcgcca agtgatggct gaattttttg
    18961 aacaagatct aaaagtgacc ttagtcgcaa aagataaatc gacggtcgag atgacggtcg
    19021 gggaattact tccatactct tttacagact taaactagtc tgagtcgctc tctgagtggc
    19081 acggtccttg tggccaacca atccatactt gcaacatcgt tgcacatctt atttaggagg
    19141 ttcagtaatg aacaagaaac aatggctagg tcttggccta gttgcagtgg cagcagttgg
    19201 acttgctgca tgtggtaacc gctcttctcg taacgcagct tcatcttctg atgtgaagac
    19261 aaaagcagca atcgtcactg atactggtgg tgttgatgac aaatcattca accaatcagc
    19321 ttgggaaggt ttgcaggctt ggggtaaaga acacaatctt tcaaaagata acggtttcac
    19381 ttacttccaa tcaacaagtg aagctgacta cgctaacaac ttgcaacaag cggctggaag
    19441 ttacaaccta atcttcggtg ttggttttgc ccttaataat gcagttaaag atgcagcaaa
    19501 agaacacact gacttgaact atgtcttgat tgatgatgtg attaaagacc aaaagaatgt
    19561 tgcgagcgta actttcgctg ataatgagtc aggttacctt gcaggtgtgg ctgcagcaaa
    19621 aacaactaag acaaaacaag ttggttttgt aggtggtatc gaatctgaag ttatctctcg
    19681 ttttgaagca ggattcaagg ctggtgttgc gtcagtagac ccatctatca aagtccaagt
    19741 tgactacgct ggttcatttg gtgatgcggc taaaggtaaa acaattgcag ccgcacaata
    19801 cgcagccggt gcagatattg tttaccaagt agctggtggt acaggtgcag gtgtctttgc
    19861 agaggcaaaa tctctcaacg aaagccgtcc tgaaaatgaa aaagtttggg ttatcggtgt
    19921 tgatcgtgac caagaagcag aaggtaaata cacttctaaa gatggcaaag aatcaaactt
    19981 tgttcttgta tctactttga aacaagttgg tacaactgta aaagatattt ctaacaaggc
    20041 agaaaaagga gaattccctg gcggtcaagt gatcgtttac tcattgaagg ataaaggggt
    20101 tgacttggca gtaacaaacc tttcagaaga aggtaaaaaa gctgtcgaag atgcaaaagc
    20161 taaaatcctt gatggaagcg taaaagttcc tgaaaaataa tggatggaag tcatttctta
    20221 ggaagcggcc aagggccgct tttttaagag ttgagacaaa gtcattttgt ctcagtaaag
    20281 cttgctacta gacaaactag caagttttat tgaaataaaa taagactctg aaaggaagag
    20341 cacatggcac acgaaaatgt cattgagatg cgtgatatta ccaaggtgtt tggtggattt
    20401 gttgccaacg acaaaatcaa cttgcaccta cgaaaaggtg aaattcatgc acttttagga
    20461 gaaaatgggg ctggtaagtc cacgctaatg aacatgttag caggccttct tgaaccaact
    20521 agtggtgaaa tcgcggtcaa cggtcaagtt gtcaatctcg actccccatc taaagcagct
    20581 agcttgggaa tcgggatggt tcaccagcac tttatgttgg ttgaagcctt cacagtggct
    20641 gaaaacatca ttttaggtag tgaattgact aaaaatggtg tgctagatat cgctggagct
    20701 agcaaagaaa tcaaggctct ttctgaacgt tatggcttag ctgttgaccc ttctgccaag
    20761 gtagcagata tctcagttgg agcccaacaa cgtgtagaaa ttttaaaaac actttatcgg
    20821 ggggctgata tccttatctt tgacgaacca acggctgttt tgactccatc agaaattgat
    20881 gagttgatgg ctattatgaa aaatcttgtc aaagaaggaa aatcaattat cttgattacc
    20941 cacaaattgg atgaaattcg cgcagtttct gaccgtgtta cagttatccg tcgtgggaaa
    21001 tcaattgaaa ccgttgaaat tgcaggggct accaatgctg atttggcgga aatgatggta
    21061 ggacgttctg tttcctttaa aacagagaag caagcctcta aaccaaaaga agtggttttg
    21121 tctatcaaag atttggtggt caatgaaaac cgtggtgttc cagctgttaa aaatctgtcc
    21181 ttggatgttc gtgctggaga gattgttggt attgcgggga ttgatggaaa tggtcagtct
    21241 gaactgattc aagccattac aggtcttcgt aaggttgaat ctggtagcat tgagctaaaa
    21301 ggagattcaa ttgtaggctt gcacccacgt cagattacag aactaagtgt tgggcacgtt
    21361 ccagaagacc gtcaccgtga tggcttgatt ttggaaatga tgatatctga aaatattgcc
    21421 cttcaaacct actataaaga accacatagt aaaaatggaa ttttgaatta ttcaaatatt
    21481 acttcttatg ctaaaaagct gatggaagag tttgatgttc gcgctgccag tgaattagtt
    21541 cctgcagctg cactctcagg aggaaatcaa caaaaagcaa ttattgctcg tgaaattgat
    21601 cgagatcctg atctccttat cgttagccag ccaactcgtg ggttggatgt cggtgccatt
    21661 gagtatatcc acaaacgctt gattgaagag cgtgataatg gcaaggctgt ccttgttgtc
    21721 agctttgaat tggatgagat tttaaacgtc tcagaccgta ttgccgttat ccacgatggt
    21781 aagattcaag gtattgtatc accagaaaca accaataaac aagaacttgg tgtcttgatg
    21841 gctggtggaa acttgggaaa ggagaagagt gatgtctaaa aaattacaac aaatttcggt
    21901 tcccttgatt tctgtatttc taggaatttt actcggagcc attgtcatgt ggatcttcgg
    21961 ttatgatgct atttggggct acgaagaatt gttctataca gcctttggca gtctgcgtgg
    22021 gattggagaa atcttccgtg ctatgggtcc tctggtcttg attggtcttg gttttgcggt
    22081 tgccagtcga gctggtttct ttaacgtcgg acttcctggt caggctttgg caggttggat
    22141 tctcagtggt tggtttgcgc tgtcgcatcc agatatgccc cgtcccttga tgattctagc
    22201 aaccatcgtg attgccttga ttgctggtgg gattgtcgga gcgattccag gtattcttag
    22261 ggcctatcta gggacgtcag aggttattgt aaccatcatg atgaactaca ttgtcttgta
    22321 tgtagggaat gcctttatcc atgctttccc taaagacttc atgcaaagta cagattcgac
    22381 cattcgtgtt ggggctaatg caacctatca gacaccttgg ttggctgagt tgactggtaa
    22441 ctcacggatg aatattggta ttttctttgc catcattgcc gttgcagtta tttggttcat
    22501 gctcaagaaa acaactcttg gttttgaaat ccgtgcagtt ggtcttaatc cacatgcttc
    22561 agaatatgct ggtatttctg ccaagcggac tattatccta tctatgatta tttcaggtgc
    22621 cttggcaggt cttggtggag ctgttgaagg tttgggaacc ttccagaacg tctatgttca
    22681 aggttcgtca ttagctatcg gatttaacgg aatggcggtt agtttgcttg cggccaactc
    22741 accaattggt atactctttg cagccttcct atttggcgtt ctccaagttg gggctcctgg
    22801 tatgaatgcg gcgcaggtac catctgagct tgtcagcatt gtaacagcgt ctattatctt
    22861 ctttgtcagt gttcattacc ttatcgaacg ctttgtcaaa ccgaaaaaac aagttaaagg
    22921 aggtaagtaa agatgtctat tataaccttg ctccccctct tggtgtcttc tatgctgatt
    22981 tactcagcac ctctcatctt tacaagtatc ggtggtgttt tctctgaacg tggtggtgtg
    23041 gtaaacgttg gccttgaagg aattatggtt atgggtgcct tttctggagt tgtctttaac
    23101 cttgaatttg cagaacaatt tggagcagca actccatggc tatccttgct tgtagcagga
    23161 ttggttggta gtgttttctc tatcatccac gcagcagcga cggttcattt ccgtgcagac
    23221 catgttgtca gcggtacggt attgaacttg atggcgcctg ccttggctgt tttcttagtt
    23281 aaagttcttt ataacaaagg acaaaccgac aacctaagtc aaacttttgg acgctttgat
    23341 ttcccagtct tggcaaatat cccagtgatt ggtgatatct tcttcaagtc aactagtcta
    23401 cttggttatc tggcgattgc cttctcattc cttgcttggt ttattctctt taagactcaa
    23461 tttggtcttc gtctccgctc tgtcggtgaa catcctcaag cagcggatac cttgggaatc
    23521 aacgtctaca agatgagata tttagggatt attatttcag gttttctagg tggaattggc
    23581 ggagcgattt atgcgcaatc aatctcagtt aacttctcag tgacaactat tgttggacct
    23641 ggatttatcg cccttgctgc gatgatcttt gggaaatgga atccaatcgg tgctatgctt
    23701 tctagtctct tctttggact ttcacaaagt ttggctgtta tcggttctca attgccgttc
    23761 ctacaaggag tgccagcggt ttatcttcaa attgcacctt atgttttgac aattcttgtc
    23821 ttagcagcct tctttggaaa agcagtcgca ccaaaagcag atggtatcaa ctacatcaaa
    23881 tcaaaataag catacaaaaa aacgtcagtc caatgactga actgcccccc aaaagttaga
    23941 cagaaaaaat ctaacttttg gggtg
//
LOCUS       DAVAZT010000033        23634 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVAZT010000033 DAVAZT010000000
VERSION     DAVAZT010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23634
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.033"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..128
                     /locus_tag="VQT45_001246"
     CDS             <1..128
                     /locus_tag="VQT45_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET2359573.1"
                     /translation="FRSLENLEQAIVDYIDYYNNKRIKVKLKELSPVQYRTKSFG"
     gene            complement(176..2719)
                     /locus_tag="VQT45_001247"
     CDS             complement(176..2719)
                     /locus_tag="VQT45_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HET2359574.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQKKVD
                     ILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTKTFT
                     EAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQAQT
                     GFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(2781..4403)
                     /locus_tag="VQT45_001248"
     CDS             complement(2781..4403)
                     /locus_tag="VQT45_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2359575.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            4609..5634
                     /gene="trpS"
                     /locus_tag="VQT45_001249"
     CDS             4609..5634
                     /gene="trpS"
                     /locus_tag="VQT45_001249"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HET2359576.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            5787..7265
                     /gene="guaB"
                     /locus_tag="VQT45_001250"
     CDS             5787..7265
                     /gene="guaB"
                     /locus_tag="VQT45_001250"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HET2359577.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(7316..8413)
                     /gene="recF"
                     /locus_tag="VQT45_001251"
     CDS             complement(7316..8413)
                     /gene="recF"
                     /locus_tag="VQT45_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HET2359578.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(8416..8784)
                     /gene="yaaA"
                     /locus_tag="VQT45_001252"
     CDS             complement(8416..8784)
                     /gene="yaaA"
                     /locus_tag="VQT45_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HET2359579.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKIDIPDMNIDILLTQSTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            8943..10193
                     /locus_tag="VQT45_001253"
     CDS             8943..10193
                     /locus_tag="VQT45_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET2359580.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSYLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHCPSKYGDEKHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSQLDLFSGFLRMYAGIDRENRNQARKMMNNQLLDL
                     KKGYFTELELEQTKEMIRRSLLLSQDNQSSLIERAYQNALLGKSSADFKSWIAKLEQV
                     DKDAICRAANNVKLQAIYFMEGIE"
     gene            10190..11473
                     /locus_tag="VQT45_001254"
     CDS             10190..11473
                     /locus_tag="VQT45_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET2359581.1"
                     /translation="MTKVVFEEKYYPAVKEMVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTLVTEVDGDVKQYPAGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELITSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKLTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            11515..12336
                     /locus_tag="VQT45_001255"
     CDS             11515..12336
                     /locus_tag="VQT45_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2359582.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            12347..12892
                     /gene="pgsA"
                     /locus_tag="VQT45_001256"
     CDS             12347..12892
                     /gene="pgsA"
                     /locus_tag="VQT45_001256"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HET2359583.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            12889..13716
                     /locus_tag="VQT45_001257"
     CDS             12889..13716
                     /locus_tag="VQT45_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET2359584.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            13701..14540
                     /locus_tag="VQT45_001258"
     CDS             13701..14540
                     /locus_tag="VQT45_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET2359585.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPNQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            14533..15327
                     /locus_tag="VQT45_001259"
     CDS             14533..15327
                     /locus_tag="VQT45_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET2359586.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            15386..16204
                     /gene="mreC"
                     /locus_tag="VQT45_001260"
     CDS             15386..16204
                     /gene="mreC"
                     /locus_tag="VQT45_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HET2359587.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKVSQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            16204..16698
                     /gene="mreD"
                     /locus_tag="VQT45_001261"
     CDS             16204..16698
                     /gene="mreD"
                     /locus_tag="VQT45_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HET2359588.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            16792..17970
                     /locus_tag="VQT45_001262"
     CDS             16792..17970
                     /locus_tag="VQT45_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET2359589.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            18194..18973
                     /gene="rpsB"
                     /locus_tag="VQT45_001263"
     CDS             18194..18973
                     /gene="rpsB"
                     /locus_tag="VQT45_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HET2359590.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            19052..20092
                     /locus_tag="VQT45_001264"
     CDS             19052..20092
                     /locus_tag="VQT45_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HET2359591.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            20339..20680
                     /gene="tnpB"
                     /locus_tag="VQT45_001265"
                     /pseudo
     CDS             20339..20680
                     /gene="tnpB"
                     /locus_tag="VQT45_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(20816..21036)
                     /locus_tag="VQT45_001266"
                     /pseudo
     CDS             complement(20816..21036)
                     /locus_tag="VQT45_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            21207..21488
                     /locus_tag="VQT45_001267"
     CDS             21207..21488
                     /locus_tag="VQT45_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HET2359592.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYKDGVDLLGYTTWG
                     CIDSVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            21620..22564
                     /gene="manA"
                     /locus_tag="VQT45_001268"
     CDS             21620..22564
                     /gene="manA"
                     /locus_tag="VQT45_001268"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HET2359593.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTILVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVESWTLEGQDLELIVSHP"
     gene            complement(22604..23521)
                     /locus_tag="VQT45_001269"
                     /pseudo
     CDS             complement(22604..23521)
                     /locus_tag="VQT45_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822901.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
BASE COUNT         7512 a         3855 c         4929 g         7338 t
ORIGIN      
        1 gctttagatc tttagaaaac cttgaacaag ctattgtgga ctacattgat tactacaaca
       61 acaaacgaat taaggtaaaa ctaaaagaac ttagccctgt gcaatacaga actaaatcct
      121 tcggataaat taattgtcta actttttggg gtcagtacat taactggtcg attttttatg
      181 ccttagatga ctttcgtctg tgattataga ttccaaatag taagagagaa gtaaaggaac
      241 agattgctcc agtaataaaa ccattgggaa tgaaggaaag tgtaatagtt cctttcccct
      301 tgggaatgtc aactttcata aatccagttt gagcttgttt aatttctatt ttcttaccat
      361 cttggtaggc agaccaacct ttgtcataag gaatggtgaa gaaaatagat gtatcttgtt
      421 ggacatcata tgtagcaaaa accttgtttt tagaagttga tactgtgaca ggttgttctt
      481 taattttttg aattgcctcg gtgaaagttt tggtatctaa acgatagaag gtaggagatt
      541 caaatgatac ttgtgaattt ccagggaaac taacattgat attgaaagtt tttttctctt
      601 tagtatatcc tagattaaag aaggagaaga cattatcagt tgtaaaagtc tttttttcac
      661 catttacaag gatgtcaacc ttcttttgtt tatcgttaga aaagtgaagg tttatgaaag
      721 agagataaac ttggctgttt tctggaactt caatttgata ctggattgct gcatcttcat
      781 ttgaagaact tgtgacacta atcaaatcat tagtattttc tgttttttca taaggtattg
      841 gagaaaaata atcaaaattg acgttagcaa gttgatttaa aaatgaggcc tgattatcca
      901 aggtatgttc attgaacttg acatcattgt aaacagattg actagcaact gcaatcggaa
      961 gagagtattg attttcatat agggtaagat tatctttttg atagatatct ttaaagccat
     1021 acttatcaat aggactgtct gagatattgt actggatacc aaataaacta tcagccaaaa
     1081 tactattatt tgcatatcgg agattgagat tagtcccaga ggatttaaaa ccaagtttat
     1141 ctaaagtaga gcttgatgaa cgatttcgaa cagatgaaaa ttgagagatt ccattgtagt
     1201 tgaatttcat actgtcattt cctgtctgag tttgtagttt ttcagtacga gtaaattgat
     1261 ttccaatata tgttgagaaa gattccatag ctgggatatc tcgactataa gcacttcgag
     1321 aagcaaatcc ccattcctta gcaattccgt ccatttgaga tgaagcattt aaactcattt
     1381 caaccagtat aaataaagag attagaatgg caaatagatt cacagatata aactttttga
     1441 taactgcaag gagtaaaaga gaatagacaa ccaaaaattc aagagtaagc agaatattca
     1501 aatctgttaa aaaagaataa tgcgatttta gatagatggt agctaaaaat cctgctacta
     1561 caagaaaaag cgaaactaaa aaattccaga ctttaagttc tttcagacgc tttaagactt
     1621 ctgctgctgt gtaaattaac aaggtagaga aaatccaagc atagcgatgt aaaaacatgt
     1681 ttggagtatg catgccttgc caaaataagt caagagcttc tatgtaaaag cttgcaatta
     1741 gaaatgcaaa gaatattaca tatatgagtt tcacgtgaaa cttaatagat ttcagcgtaa
     1801 aaaataaaat ggtcaaaata aagggaaata gtccaacaaa aatcattggg atggccccat
     1861 actttgttgt gtcaaaggaa ccaatgaatt gcttagcaaa gagatcaaga taccagctac
     1921 tttcagtttg aaactttgta acttcagtca atttttcccc atgtgtctgt aaatcaaata
     1981 gagtgggaag agtcataatc aaactagcca taccagctaa aaaggagata actatgaaat
     2041 caagaacaga tgattttcga gtcttaaagt cccacgaaat ttgacagaga taccagaaaa
     2101 taagaaacaa tactgtcata tatccaaaat aataattttg aataaataag attgacagac
     2161 ttgtaaagta caataggagt ttcttttcag ttatcagtag atgtaaacca gttataatta
     2221 aaggaatcaa gataaaaaca tctagccagg tttttatctc taattgactg acagtgaaac
     2281 tcatcagagc ataggaagta gataaggcta gttttaaagt ctgagggata gattgaaaca
     2341 atttattcaa actaaaaaag gttgacagac caatcaatcc aaattttaag agagtggtca
     2401 gatagacagc atctggcata ttcgttagat caaaaaagta aactagaggc gcgagaaaac
     2461 tacccaagta ataactagat agggcataga agtttagccc tagaccactt gtaaaggtgt
     2521 aaaacagact actatttcca tgtaggatat ttcgtaaggc tacatcaaaa ataacgtatt
     2581 gatgaaagcc atctcctaat agaggagagt tgtcgctatt ccagtagata ccttgagata
     2641 gatatactcc agacataatc actacaggaa tgatgaaaga aataaaatag gttcgatatg
     2701 tttttaaaaa tgatttcatg ttacctcgta gaatgataga aaactcagtt ggttaaccca
     2761 actgagtttt gaagttttat ttagtctttc caaagttctt taacttttgc ttgtacttct
     2821 gcattttcta ggaattcatc gtaggtttca tcgatacggt caatgacgcc atttttagat
     2881 aagacaatga tatggttagc caaagtttga ataaactcgt ggtcatggct ggcaaagatg
     2941 attgattctt taaagttttt cagtccatca ttcaagcttg agatagattc caagtccaag
     3001 tgatttgttg gatcatcaag tacaaggaca tttgatttta agagcatgag ttttgaaagc
     3061 atgacacgaa ctttttctcc ccctgacaag acatttacag gtttgttaac ttcatctcca
     3121 gagaagagca tacggccgag gaaaccacgt aggaaagtat tgtcatcttc ttctttactt
     3181 gcgaattgac gcaaccagtc aagaattgat tctcctcctg caaaatcagc tgagttatct
     3241 tttggtaggt aagattgact agttgtaact ccccacttga cagttccttc atagtcaata
     3301 tctcccatga ttgcacgaat taatgcagtc gtttgaatat cattttgtcc aataagtgct
     3361 gtcttatcat ctggacgcaa gatgaaacta atattatcca agatagtttc accatcaatc
     3421 tttacagtta gattttctac tgtcaagaga tcattaccaa tctcacgttc cgctttaaag
     3481 ttgataaatg gatatttacg actagatggt acaatctctt ctagctcaat cttatcaagc
     3541 attttcttac gtgatgttgc ctgccttgac ttagaagcat tggcagagaa acgagcaacg
     3601 aattcttgca attgtttaat tttttcttct gctttagcat tacggtctgc tagcaattta
     3661 gcagcaagct cagaagattc cttccagaag tcgtagtttc cgacatagag tttgattttt
     3721 ccaaagtcaa ggtcggccat gtgagtacaa actttgttta agaagtgacg gtcgtgggat
     3781 actacgataa ctgtgttatc aaagtcaatc aagaagtctt ctaaccaagt aatcgattgg
     3841 atatccaaac cgttagtagg ctcgtccaag agaagaacat ctggtttacc aaaaagtgct
     3901 ttggcgagga gaacctttac tttttcaccg ttggccaatt cgctcatgtt ttggtagtgt
     3961 aattcttctg gaatgtttag gttttgaagt agttgagagg cttcactctc tgcttcccaa
     4021 cctccaagtt cggcaaactc tccttcgagt tcggcagcac gaaccccgtc ctcgtctgag
     4081 aaatcttcct tcatgtagat agcatctttc tctttcatga tgctataaag tttttcattt
     4141 cccatgataa cgacatcaat ggcacgttca tcttcgtagt caaagtgatt ttgacgaaga
     4201 acagagagac gttcatctgg accaagagag atgtgaccag tagtaggttc gatatctcca
     4261 gctaaaattt ttaaaaaggt tgattttccg gcaccattag caccgattaa tccgtaagta
     4321 tttccttctg taaatttgat attgacatca tcaaaaagtt tgcgatcact aaaacgtagt
     4381 gaaacatcag atactgtaag caatgttttt ctcctatatg tgtaatatat ttattctact
     4441 agaaaataca gaaatattca aatttttatt tgtcaatttt gtgtaaatta tatttacagt
     4501 atcctttaca caaatctgta aaaagcaagg ctgatttatt ttgataaatt acggttattt
     4561 cattaaaaaa atgctataat tgaaaggact atatcgaagg agaacaaaat gactaaaccc
     4621 attattttaa caggagaccg tccaacagga aaattgcata ttggacatta tgttggaagt
     4681 ctcaaaaatc gagtattatt acaggaagag gataagtatg atatgtttgt gttcttggct
     4741 gaccaacaag ccttgacaga tcatgccaaa gatcctcaaa ccattgtaga gtctatcgga
     4801 aatgtggctt tggattatct tgcagttgga ttggatccaa ataagtcaac tatttttatt
     4861 caaagccaga ttccagagtt ggctgagttg tctatgtatt atatgaatct agtttcgtta
     4921 gcacgtttgg agcgaaatcc aacagtcaag acagagattt ctcagaaagg atttggagaa
     4981 agcattccga caggattctt ggtctatcca atcgctcaag cagctgatat cacagctttc
     5041 aaggctaatt atgttcctgt tgggacagat cagaaaccaa tgattgagca aactcgtgaa
     5101 attgttcgtt cttttaacaa tgcatataac tgtgatgtct tggtagagcc ggaaggtatt
     5161 tatccagaaa atgagagagc agggcgtttg cctggtttag atggaaatgc taaaatgtct
     5221 aaatcactaa ataatggtat ttatttagct gatgatgcgg atactttgcg taaaaaagta
     5281 atgagtatgt atacagatcc agatcatatc cgcgttgagg atccaggtaa gattgaggga
     5341 aatatggttt tccattatct agatgttttt ggtcgtccag aagatgctca agaaattgct
     5401 gatatgaaag aacgttatca acgaggtggt cttggtgatg tgaagaccaa gcgttatcta
     5461 cttgaaatat tagaacgtga actgggtcct attcgtgagc gccgtattga atttgctaag
     5521 gatatgggag aagtttataa tatgattcaa aaaggtagtg aaagagcgcg tgaagttgcg
     5581 ggtcaaaccc tatctgaggt aaaaggggca atgggacttc attactttaa ctaagtttat
     5641 tttacaagaa actatcattt ctatctcgaa gaaaagatag tttttttatt tacccctgta
     5701 acatttgaca aatttttata gaatggtatg atagatacaa tataaaaaga gtcaagctca
     5761 aaaagaaaga aaagaggaaa cttcgaatgt ctaattggga cactaaattt ttgaaaaaag
     5821 gttttacctt tgatgatgta ttgcttattc cagctgaaag tcatgtgttg cctaacgatg
     5881 cagatttaac aactaaattg gcagataatt tgactttaaa tatcccaatt attaccgctg
     5941 ccatggacac agttacagag agtcaaatgg ccattgctat tgctcgtgca ggcggtctcg
     6001 gagttatcca taaaaacatg tcaattgctc aacaagcaga cgaggttcgt aaggtaaaac
     6061 gttctgaaaa tggagttatt attgatccgt tcttcttgac gcctgaacat acaattgctg
     6121 aagcagatga gcttatgggt cgttaccgca tcagtggtgt tccagttgtt gaaacacttg
     6181 aaaatcgtaa attggttggt attttgacaa accgagatct tcgttttatt tcagattata
     6241 atcaaccaat ttcaaaccat atgactagtg aaaatcttgt tactgctcct gtgggtacgg
     6301 atcttgcaac ggctgagagt attcttcaag agcatcgtat tgaaaaactt ccgttggtcg
     6361 atgaagaagg cagtctttct ggtttgatca ctatcaaaga tattgaaaaa gttattgagt
     6421 ttccaaatgc ggctaaagat gagtttggtc gtcttctagt tgcaggtgca gtaggtgtta
     6481 cttcagatac atttgaacgt gcagaggctc tttttgaggc aggagcggat gcgattgtta
     6541 ttgatactgc acatggtcat tctgcaggtg tcttgcgtaa aattgccgag attcgtgctc
     6601 atttcccaga tcggactttg attgctggaa atattgctac tgctgaaggt gcacgtgccc
     6661 tttatgaagc gggtgtagac gttgttaagg ttggtattgg accaggttct atctgtacta
     6721 ctcgtgtgat tgctggtgtt ggtgttccgc aagtaacagc tatctacgat gctgcagctg
     6781 ttgcgcgcga atatggtaaa acgattattg ctgacggtgg gatcaagtat tctggagata
     6841 ttgtaaaagc acttgctgca ggtggaaatg ctgttatgct tggatctatg tttgctggaa
     6901 ctgatgaagc tccaggcgaa actgaaatct tccaaggacg taaattcaag acttaccgtg
     6961 gtatgggatc aattgctgct atgaagaaag gttcaagcga ccgttatttc caaggttctg
     7021 tcaatgaagc aaacaagctt gttccagaag gaattgaagg tcgtgttgct tataaaggag
     7081 cggcagctga tattgttttc caaatgattg gtggtattcg ctctggtatg ggttactgtg
     7141 gtgcagctaa ccttaaagaa ctacacgata atgctcaatt tattgaaatg tctggtgctg
     7201 gtttgaaaga aagccatcct catgatgtgc aaattactaa tgaggcacca aattattcta
     7261 tgtaaaaaac aatgaaaaga actccagtga aaacaggagt tcttttacaa tgttgtcaat
     7321 ttccatttac agcagcttta ccatcctgaa tagtgaagat acttagattt tctggcagat
     7381 tttgaagatg gtctaagctt gttgttgtga taaaggtttg gattgattga gaaatcgttt
     7441 ctaataattt taactgtcta gtgttgtcaa gttcactcat cacatcgtca agcagtaata
     7501 taggagattc tgtggtaatg ctttccatta attcgatttc tgctaatttt atcgagagga
     7561 cgagactacg atgttgacct tggcttccga aactagcatc catcccattt atataaaaag
     7621 aaatgtcatc tcgatgagga ccgacaccag tattcttttt aaataaatct ctggatctac
     7681 ttttttctaa agcaattttg aaagattcgg ataagttttg tttgtcagtt atattgacag
     7741 aagattgata ggatattgac aactcttcga tctgattaga gagttcaaaa tgtttcttac
     7801 gcccaaatga ttctagtttt tttatgaaat ctaagcggtg attcattaca cgacatccat
     7861 aatcaactag ctgatcatct aacacagaaa ggaatgtttc atctattttt tgagctgatt
     7921 ttaggtaagt gtttctttgc tttaggatgt ggttataatt ggttaagtca gataaataga
     7981 ttggcttaat ttgcccaagt tccatatcaa tgaattttcg tcgaatcgaa ggtgctcctt
     8041 taattagttg taaatcttca ggagcaaata agacaacatt catgtgtcct acataatctg
     8101 aaaggcgtgc ctgttttaag tgattaactt ttgttacacg gcctttttgt gttagttcga
     8161 tttctagggg aatggatcca gtttttttct gaacgagacc tgaaagatga agttgttcct
     8221 catcaaaatg aatgagattt ttatctgttc gagttcgatg actacgcgtt aaggctaaaa
     8281 aatagatagc ctctaacatg tttgtttttc cttgtgcatt acgtcccaaa aagacattca
     8341 atttaggatt aaagtctatt ttcgtttctt tgtaattacg aaaagtcttg agagatagat
     8401 gttgtagcca catgattatc taccagggaa tcgtggagct tgttggcttt taggtgatga
     8461 agcaggtttc gatttgtctt ttttaactcc cttattcatc tttttgacaa gtttagcgat
     8521 ccgttctttt tcaactttat cagcttggta ttcatcttgt tcttcagaag tagattgtgt
     8581 caacaagatg tcaatgttca tgtcagggat gtcaatttta tcgccaatac gaagtttttt
     8641 accacgacga ctctctaatt ccctattaaa gtaaacagaa tgttcagaga gaaatgattt
     8701 aatagctcct ccgctatgtg taattccaag ttctttgagt agtgcttgga gggtaataaa
     8761 ttcttcaaat aatttgtatt ccataattca cctcaatctt tggtattata ccatattttc
     8821 ctaaaaatag tgagagatac agcgagaaat gtaagcgatt tttatttcaa aagtgttaca
     8881 gggaacaaga aaatttcagg ttttcgtgat ataatagaag tctgtatata aggagataaa
     8941 tcatggagtt agtgcatgga atttcaacac attttatcca atcaaaaaag tttaaaacaa
     9001 acaaaattac cgtgcgtttt accgctccat tatcccttga tacgattgca ggtcacatgt
     9061 tgagtgcaag tatgctagag actgctaatc agatgtaccc cacttctcaa gatttgagga
     9121 gacacttggc cagtctatac ggtacagata tgtcaaccaa ttgtttcaga agagggcaaa
     9181 gccacattat agaattgaca tttacctatg ttcgtgatga gtttttaagt aggaaaaacg
     9241 tgctaacttc tcagattttg gaacttgtaa aagaaactct tttttcaccc gtagtagttg
     9301 ataatgggtt tgatccggcc ttatttgaaa ttgagaaaaa acaattgcta gcaagtttag
     9361 cagctgatat ggatgattct ttttattttg cacataaaga attggataaa ttgttttttc
     9421 atgatgaacg tcttcaattg gaatatagtt atttacgaaa tcgtatttta gctgaaactc
     9481 cacaaagttc ttattcttgt ttccaagaat ttttagccaa tgatcgaata gatttctttt
     9541 tcctaggtga ttttaatgag gttgaaattc aaaatgtatt agaatcattt ggctttaaag
     9601 gtcgaaaagg agatgtgaag gttcagtatt gtcaacctta ttctaatatc cttcaggaag
     9661 gtatggttcg gaaaaatgtg ggacaatcca ttttggaatt aggttatcat tgcccttcta
     9721 aatatggtga tgagaaacat ttacccatga ttgtaatgaa tggtttactt ggtggatttg
     9781 ctcactctaa actttttaca aatgtccgtg aaaatgctgg attagcttat actatttcaa
     9841 gtcagctcga tttatttagt ggattcttga ggatgtatgc tggtattgac cgagaaaatc
     9901 gtaaccaggc tcgtaaaatg atgaataatc aactgcttga tttaaaaaaa ggttatttta
     9961 cagagcttga gttagagcag accaaggaaa tgattcgtcg gtctttgtta ctttctcaag
    10021 ataaccaatc ttcattgatt gaacgtgctt atcaaaatgc cttacttgga aaatcttcag
    10081 cagattttaa aagttggatt gcaaaactcg agcaagttga caaagatgct atttgtagag
    10141 cagctaacaa tgtgaaacta caagcgattt actttatgga aggaatagaa tgacaaaggt
    10201 tgtttttgaa gaaaaatact atccagctgt aaaagaaatg gtttatcgaa ctcgtttggc
    10261 aaatggattg acagtagctc ttttgcctaa aaaggaattt aaagaggttt acgggagtgt
    10321 aactgtacag tttggttcgg tagatacgct tgtcacagaa gttgatggag atgtaaaaca
    10381 atatcctgca ggaattgctc attttcttga acataaatta tttgaaagag aagattctag
    10441 cgatttgatg tcggctttta cgagtctagg tgcagatagt aatgccttta caagctttac
    10501 aaaaacaaac tatctttttt cagcaacgga ttatttttta gaaaatttag atttacttga
    10561 tgaattgata acatcagcac actttactga agcttccatt ctgacagagc aggatattat
    10621 tcagcaagaa cgagaaatgt accaagatga tccagattcg tgtttattct tttcaacttt
    10681 agcgaatttg tatcctggta cacctttagc aactgatata gttggaagtg aggagtccat
    10741 ttcccaaatc aatctaacta atttgcaaga aaattttaca aagttttaca aacctgtaaa
    10801 catgtctctg tttttagttg gtaattttga tgtggagcga gtacaggact attttgaaag
    10861 caaagaactg aaagattcag attttcagga agtagcaaga gaaaagttgt ttttacagcc
    10921 tgtaaagcta acagatagta tgagaatgga agtatcttct cccaaactag cgattggagt
    10981 tagaggtaag cgagaagttt ctgaagcgga ttgctatcga catcatattt tattaaaatt
    11041 attgtttgca atgatgtttg gttggacttc ggatcgtttt caaaaatgtt atgaatcagg
    11101 taaaattgat gcgtccttat ctctggaagt tgaaataaca agtcgctttc attttgtcat
    11161 gttgacaatg gatacgaaag agccagttgc tttgtctcat caatttagga aggctattcg
    11221 taattttaca aaggatttag atattacaga ggaacattta gatattatca aaagagagat
    11281 gtttggcgaa tttttcagta gcatgaactc tcttgaattt attgcaacgc aatatgatgc
    11341 ttttgaaaat ggtgagacaa tttttgattt gccgaaaatt ttacaggaaa ttactttaga
    11401 ggatgtcctt gatgctggac atcatttaat agatgatggt gacatagttg attttacaat
    11461 atttccatcg tagtaaccta tcataataga cactagaaag aagggatgac aagtatgaga
    11521 aaaaaaacaa ttggagaggt tttacgatta gctagaatca atcagggatt gagtttagat
    11581 gaattgcaga aaaagacaga aatccagtta gatatgttgg aagcaatgga agcagacgat
    11641 ttcgatcaac ttccaagtcc tttttacacg cgttctttct tgaaaaaata tgcatgggct
    11701 gttgagttag atgaccaaat tgttttggat gcttatgatt ctgggagtat gattacttat
    11761 gaggaagtag atgttgatga agatgagttg acaggtcgta gacgttcaag taagaaaaag
    11821 aagaaaaaaa catcattttt acctttattt tattttatcc tttttgcttt atcgatttta
    11881 atttttgtga cttattatgt ttggaactat attcaaactc aaccagagga gccttctctt
    11941 tctaattaca gtgtggttca atcaacaagt tcaactagct ctgttcccca ctcctcaagt
    12001 agtagttctt ctagtataga atcagctata agtgtatcag gcgaaggaaa tcatgtagaa
    12061 atcgcttata agacaagtaa ggaaacagtt aaattgcaat tggcagtttc agatgttaca
    12121 agttgggtca gtgtttcaga aagcgaactt gagggcggtg taaccttatc gccaaagaag
    12181 aaaagtgcag aagcaacagt tgcaactaaa agtcctgtaa caattacgtt aggtgttgta
    12241 aaaggtgttg atttgacagt agataatcag actgttgatt tatcgaaatt aacagctcag
    12301 actggacaaa tcactgtaac ctttactaaa aattaaggaa aaacgaatga aaaaagaaca
    12361 aattcccaat ctcttaacaa taggtcgaat tctctttata cctattttta tctttatttt
    12421 aacgatagga aattcgatag agagtcatat agttgcagct attatctttg ctgttgccag
    12481 tattaccgac tatttagatg gatatttagc tcgtaaatgg aatgtggtca gtaattttgg
    12541 taaatttgca gatcctatgg cggataagtt actagttatg tcggctttta ttatgttgat
    12601 tgagttaggt atggctccgg cttggattgt tgcagtgatt atatgtcgtg agttagctgt
    12661 gacaggttta aggcttttat tggttgaaac tggtggaaca attttagcag cagcaatgcc
    12721 tggaaaaatt aaaactttta gtcagatgtt tgctattatt ttcttgctat tacattggac
    12781 tttgcttggt caagttctac tttatgtagc cttatttttc actatctact ctggctatga
    12841 ctattttaag ggtagtgcct atgtatttaa agggacattt ggttcgaaat gaaatcaata
    12901 attgatgtaa aaaatctttc ttttcgctat aaagaaaatc agaactacta cgatgtgaag
    12961 gatattacgt ttcacgtgaa acgtggagaa tggctttcga ttgtagggca taatggtagt
    13021 ggtaaatcaa cgacggttcg attaattgat ggcttactgg aagcagaatc cggagagatt
    13081 gtaattgatg gccaacgttt gactgaggaa aatgtttgga atatacgtcg tcaaatcggt
    13141 atggtttttc aaaatccaga caatcaattt gttggagcga ctgttgaaga tgatgttgct
    13201 tttggtttgg aaaatcaggg actttctcgt caagaaatga aaaagagagt ggaagaagct
    13261 ctggctttag ttggcatgtt ggactttaaa aagagagagc cagcgcgtct atcaggtggt
    13321 caaaagcaac gtgtggccat tgcaggtgtt gtagccctaa gaccagctat tttaatctta
    13381 gatgaagcaa cgagtatgtt ggatcctgag gggcgtagag aacttattgg gacagtaaaa
    13441 ggaattcgaa aagactatga tatgacggtc atttctatta cccatgattt ggaagaagtc
    13501 gccatgagtg atcgcgtatt ggtcatgaaa aaaggggaaa ttgaatcaac tagtagtcca
    13561 agggagcttt tctctcgaaa tgatttagat caaattggat tagacgatcc ttttgctaat
    13621 caattaaaaa aatctttgag ccagaatggc tatgatttac ctgaaaatta tttgacagaa
    13681 agtgagctag aggataagct atgggaattg ctctagaaaa tgtgaatttt acatatcaag
    13741 aaggtactcc cttagcttca gcagctttgt cggatgtttc tttgacgatt gaagatggct
    13801 cttatacagc tttaattggg cacacaggta gtggtaaatc aactatttta caactcttaa
    13861 atggtttatt ggtgccaaat caagggagtg tgagggtttt tgatacctta atcacctcga
    13921 cttctaaaaa taaagatatt cgtcaaatta gaaaacaggt tggcttggta tttcagtttg
    13981 ctgaaaatca gatttttgaa gaaacggttt tgaaggacgt tgcttttgga ccgcaaaatt
    14041 ttggagtttc tgaagaagat gctgtgaaga ctgcgcgtga gaaactggct ctggttggaa
    14101 ttgatgaatc actttttgat cgtagtccgt ttgagctgtc agggggacaa atgagacgtg
    14161 ttgccattgc aggcatactt gccatggagc cagctatatt agtcttagat gagccaacag
    14221 ctggtctaga tcctctaggg agaaaagagt tgatgaccct gttcaaaaaa ctccaccagt
    14281 cagggatgac catcgtcttg gtaacgcatt tgatggatga tgttgctgaa tatgcgaatc
    14341 aagtctatgt aatggaaaag ggacgtttag taaagggggg caaaccaagt gatgtctttc
    14401 aagacgttgt ttttatggaa gaagttcagt tgggagtacc taaaattacg gccttttgta
    14461 aacgattggc tgatagaggc gtgtcattta aacgattacc gattaagata gaggagttca
    14521 aggagtcgct aaatggatag tatgatttta gggcgttata tcccagggga ttcgattgtt
    14581 caccgattgg atccacgtag caaattgctt gctatgatgc tactgatttt gattgtgttt
    14641 tgggctaata accccttgac gaatctgatt ctttttatag cgacagggat atttattgcc
    14701 ttgtcaggag tatctctttc attttttatt cagggcttga agtctatgtt tttcttgatt
    14761 gccttcacaa ctatttttca actatttttc atttctaatg ggaatgtttt atttgagttt
    14821 tcgtttgtga gaatcacgga ttatgctttg caacaagctg ggattatttt ttgtcgcttt
    14881 gtattgatta ttttcttttc aactttgtta accttaacaa ccatgccttt aagtttggca
    14941 tcagctgtcg aagctttatt agcaccttta aagcgtgtga aagttccagt tcatgaaatt
    15001 ggattgatgc tgtctatgag tttgcgtttt gtcccaacct tgatggatga tacgactcgg
    15061 attatgaatg cacagaaagc tcgtggagtg gattttggag aaggaagcat cgttcaaaaa
    15121 gtaaaggcga tgattcccat tttgattcct ctttttgcga caagtttaaa acgtgcagat
    15181 tccttggcta tcgctatgga agcgcgtggc tatcagggtg gaaaaggcag aagtcaatac
    15241 cgacaattga aatggactct aaaggatacg ctgaccattc ttgttattct cgtacttggt
    15301 tgttgtttat ttttcttaaa atcttagtag ctttcaggaa ttgataaaaa gttactgtaa
    15361 cagtttttga tataaaggta ggaatatgaa ccgttttaaa aaatcaaaat atgtcattat
    15421 tgtttttgtc actgttctgc ttgtgtcagc tctcttagcg acgacttatt caagtacaat
    15481 tgtgacaaaa ttaggagatg gaatctcatt ggttgataga gttgtacaaa aaccttttca
    15541 gtggtttgat tctgtcaaat cagatttggc tcatttgaca cgaacatata atgaaaatga
    15601 aagtttgaag aaacagcttt accaattaga agttaaatca aatgaggtgg aaagtttaaa
    15661 gacagaaaat gaacaactgc gccaattgct tgatatgaag tctaaattgc aagccacaaa
    15721 gactttagca gcagatgtta ttatgcgttc tccggtatct tggaagcagg agttgacctt
    15781 agatgcaggt agatcaaaag gtgcttctga gaacatgtta gctattgcaa atggtggctt
    15841 gattgggagt gtttcaaaag tagaggagaa ctctactata gtcaaccttc tgacaaatac
    15901 ggaaaatgct gataagattt ctgttaaaat tcaacatggc tctactacaa tttatggaat
    15961 tattattggc tatgacaagg aaaatgacgt tcttaaagtt agccaattaa atagtaatag
    16021 cgatattagt gcgggagata aggtgactac tggtggatta ggaaacttta acgttgctga
    16081 tattcctgtt ggtgaagtgg ttgccacaac gcatagtaca gactatttga cacgagaagt
    16141 aactgttaaa ttgagtgcag atactcataa tgtagatgtg atagaattag tggggaattc
    16201 ataatgagac agttgaagcg agttggagta tttttattgc ttcctttctt tgttctaatt
    16261 gacgcccata ttagccagct tctgggctca tttttccccc atgtacattt ggctagtcat
    16321 tttctttttc tatttctctt atttgagacg atagaagtat cagagtatct ctacctagtc
    16381 tattgttttg ttataggctt ggtttatgat gtttactttt tccatctaat agggattaca
    16441 actctcttat ttatcttatt gggagccttc cttcataaat tgaatagtgt tattttgttg
    16501 aatcgttgga caagaatgct agctatgatt gtactgacat tcctgtttga aatgggtagt
    16561 tatcttttgg cttttatggt agggttgaca gtagatagca tgtcgatttt tatagtctat
    16621 agcttggtac cgacgatgat tttaaatttt ttatggatta ctgtttttca atttattttt
    16681 gaaaaatatt atctataaga acgacatata aatgtaacaa aggcgtaata tttattaggc
    16741 ctttttttgg tatactagta ttgtctttaa aagaaggagt atctacgtaa tatgaagaaa
    16801 aaaatcttag cgtcactttt attaagtaca gtaatggttt ctcaagtagc tgttttaaca
    16861 actgcgcatg cagaaacgac tgatgacaaa attgctgctc aagataataa aattagtaac
    16921 ttaacagcac aacaacaaga agcccaaaaa caagttgacc aaattcagga gcaagtatca
    16981 gctattcaag ctgagcagtc taacttgcaa gctgaaaatg atagattaca agcagaatct
    17041 aagaaactcg agggtgagat tacagaactt tctaaaaaca ttgtttctcg taaccaatcg
    17101 ttggaaaaac aagctcgtag tgctcaaaca aatggagccg taactagcta tatcaatacc
    17161 attgtaaact caaaatcaat tacagaagct atttcacgtg ttgctgcaat gagtgaaatc
    17221 gtatctgcaa acaacaaaat gttagaacaa caaaaggcag ataaaaaagc tatttctgaa
    17281 aaacaagtag caaataatga tgctatcaat actgtaattg ctaatcaaca aaaattggct
    17341 gatgatgctc aagcattgac tacgaaacag gcagaactaa aagctgctga attaagtctt
    17401 gctgctgaga aagcgacagc tgaaggggaa aaagcaagtc tattagagca aaaagcagca
    17461 gctgaggcag aggctcgtgc agctgcggtg gcagaagcag cttataaaga aaaacgagct
    17521 agccaacaac aatcagtact tgcttcagca aacactaact taacagctca agtgcaagca
    17581 gtatctgaat ctgcagcagc acctgtccgt gcaaaagttc gtccaacata cagtacaaac
    17641 gcttcaagtt atccaattgg agaatgtaca tggggagtaa aaacattggc accttgggct
    17701 ggagactact ggggtaatgg agcacagtgg gctacaagtg cagcagcagc aggtttccgt
    17761 acaggttcaa cacctcaagt tggagcaatt gcatgttgga atgatggtgg atatggtcac
    17821 gtagcggttg ttacagctgt tgaatcaaca acacgtatcc aagtatcaga atcaaattat
    17881 gcaggtaatc gtacaattgg aaatcaccgt ggatggttca atccaacaac aacttctgaa
    17941 ggttttgtta catatattta tgcagattaa tttacagagg gactcgaata gagccctctt
    18001 ttcaggtttt accgtgacaa tccctattaa aaattatatc aaaatagctt gaaaatattg
    18061 gaaaagtatg gtaaaatgaa aattgtcgtg tgaacgataa tactcattct tgatgaattg
    18121 tgaagcagtt gcccttgggt cgttttgcga gttgaagtca agaagaggaa aaaaacaaaa
    18181 aggagaaata ctcatggcag taatttcaat gaaacaactt cttgaggctg gtgtacactt
    18241 tggtcaccaa actcgtcgct ggaatcctaa gatggctaag tacatcttta ctgaacgtaa
    18301 cggaatccat gttatcgact tgcaacaaac tgtaaaatac gctgaccaag catacgactt
    18361 catgcgtgat gcagcagcta acgatgcagt tgtattgttc gttggtacta agaaacaagc
    18421 agctgatgca gttgctgaag aagcagtacg ttcaggtcaa tacttcatca accaccgttg
    18481 gttgggtgga actcttacaa actggggaac aatccaaaaa cgtatcgctc gtttgaaaga
    18541 aattaaacgt atggaagaag atggaacttt cgaagttctt cctaagaaag aagttgcact
    18601 tcttaacaaa caacgtgcgc gtcttgaaaa attcttgggc ggtatcgaag atatgcctcg
    18661 tatcccagat gtgatgtacg tagttgaccc acataaagag caaatcgctg ttaaagaagc
    18721 taaaaaattg ggaatcccag ttgtagcgat ggttgacacc aatactgatc cagatgatat
    18781 cgatgtaatc atcccagcta acgatgacgc tatccgtgct gttaaattga tcacagctaa
    18841 attggctgac gctattatcg aaggacgtca aggtgaggat gcagtagcag ttgaagcaga
    18901 atttgcagct tcagaaactc aagcagattc aattgaagaa atcgttgaag ttgtagaagg
    18961 cgacaacgct taatttatac aaatagtaat tacctaggag ggcggggctt agcccggctc
    19021 tcctattttc aaaaaatata ggagaattaa aatggcagaa attacagcta aacttgtaaa
    19081 agagttgcgt gaaaaatctg gtgccggtgt tatggacgct aaaaaagcgc ttgtagaaac
    19141 agacggtgac atcgaaaaag cgattgaatt gcttcgtgaa aaaggtatgg ctaaggcagc
    19201 taagaaagct gaccgtgttg ctgcagaagg tttgactggt gtttatgtta acggtaatgt
    19261 tgcagcagtt attgaagtaa acgctgaaac tgacttcgtt gcaaaaaacg ctcaattcgt
    19321 tgaattggta aatactacag ctaaagtcat tgctgaagga aaacctgcta acaacgaaga
    19381 agctcttgct ttgataatgc cttcaggtga aactcttgaa gctgcatacg tatctgcaac
    19441 agcaactatc ggagagaaaa tctcattccg tcgctttgca ttgattgaaa aaacagacgc
    19501 acaacacttt ggagcatacc aacataacgg tggacgtatc ggtgttattt cagttgttga
    19561 aggtggagac gaagcacttg ctaaacaatt gtcaatgcac atcgcagcga tgaaaccaac
    19621 agttctttct tacaaagaat tggatgagca attcgttaaa gatgagttgg cacaattgaa
    19681 tcacgttatc gaccaagaca acgaaagccg tgcaatggtt aataaaccag ctcttccaca
    19741 cttgaagtat ggatcaaaag ctcaattaac tgatgatgtt attgctcaag ctgaagctga
    19801 catcaaagct gaattggctg cagaaggcaa accagaaaaa atctgggaca aaattattcc
    19861 aggtaaaatg gatcgcttca tgcttgataa cactaaagtt gaccaagctt acacacttct
    19921 tgcacaagtt tacatcatgg atgacagcaa gacagttgaa gcataccttg aatcagttaa
    19981 cgcttcggta gttgagtttg ctcgctttga agttggtgaa ggtatcgaga aagctgcaaa
    20041 cgacttcgaa gctgaagttg cagctacaat ggcagcagcc ttgaataact aataatagaa
    20101 aggaagcaaa ttgcttcctt ttttgtatag ggcttagatt tttcctgaaa ttgttttttc
    20161 cccagtctca ctcgattaga ataattaaaa caaaaagccc tataataagg gctaagtgca
    20221 tttaggagac tatacttcaa attcatagta agcgcgttca taacaaggta tctatcctaa
    20281 ttccccaact tccagtatac tagataaaaa ataattatcg gagtaaaggt attgtactat
    20341 gataattcaa ctaagtgatt taggtcaagt tcaccttgtt tgtggcaaga cagatatgag
    20401 gtagggaata gactcattag cctatgtagt taaaacccac tttgaattgg attctttctc
    20461 cggtcaagtc tttctctttt gtggtgaacg taaagaccgc tttaaagccc tttactggga
    20521 tggtcaagga ttttggctac tatataaacg ctttgagaac ggaaaactga cttggctaag
    20581 tacagaaaag gatgtcaaag ctctcgcacc tgaacaagta gattggctta tgaagggctt
    20641 ttctatcact ccaaaatata gtatattgaa actagaatag tacacctctg cttctaaaac
    20701 attgttagaa atcgatttga ctgtcctgat cgatttatcc tgttcttatt tcattttact
    20761 ataaatctat cagaaagttg tgatttctat tgaaatgagg actttctttt tacactcatc
    20821 tgctttcaaa aagcattcta gtccgtctcc gattaacgat ggactttatc acctccttct
    20881 ccagtccttg tatgacatct tccaaagttc gaaaggcttt attcttaaat ccacgtttat
    20941 gaatctcttt ccacacttgt tcgatgggtt catctctggt gtgtatggag gaataaatgc
    21001 aaaaccaata ttagtcggag tctttataag atttgcccat cagacgaaat agaatgattt
    21061 gaaggcattt atgatattta gctgtacgag agtctttaaa aagtgttttg atggtttgga
    21121 tttcttcttt agttgatttc atatcactat tatataatgc tttttgattt tagtatagta
    21181 ttatcgtaga aaatggactc ggtgctatgg atacaccgga tgagaatggt tatgtagcag
    21241 atgactatcg gattacttac ttagaggccc acatcaaggc catgcgagat gccatttaca
    21301 aagacggggt tgacttgctt ggttatacga catggggctg tatcgattcg gtttcagctg
    21361 gcacagggga aatgaataag cgctatggct ttatctatgt agatcgagat aatgtaggaa
    21421 atgggactct caaacgtagc aagaagaagt ccttctattg gtacatgtca tttatagcaa
    21481 tggtgtaagc atcgagtaga gcacatttgt ttactatttt tataaaatct tctccctgct
    21541 ttataagatg taaaaaagag ttcaaatgga actctttttt tgctataatg aggggagaaa
    21601 aatcagacag gagattaaga tgtcagaacc attattttta caatcagtta tgcaagaaaa
    21661 aatctggggt ggtaccaagc tacgtgatga gtttggctac gacatcccaa gtgaaaaagt
    21721 cggagagtac tgggctatct cagctcatct aaatggtgtt tctaaagttg ccaatggtcg
    21781 ttacgaggga acagatcttg ctactttgta tgcggaacac cgtgaattat ttggcaatcg
    21841 tccagaacct gtatttccac ttttgaccaa gatcctcgat gccaacgact ggctcagtgt
    21901 ccaagttcac ccagacgatg cttatggact cgagcatgaa ggcgaacttg gaaaaacaga
    21961 atgttggtac atcattgcag cagatgaagg ttcagagatt atctacggtc acaatgccaa
    22021 gtcaaaagaa gaactccgcc agcaaatcga ggataagaac tgggatgcgc tgttgacaaa
    22081 agtgccagtt aaagcaggag atttcttcta tgtaccaagc ggtaccatgc acgctatcgg
    22141 ggcgggtatc ttgattcttg aaacccagca gtctagcgat accacttacc gtgtctatga
    22201 ctttgaccgt aaggatgaca agggcaattt acgtgaactt caccttgaaa aatctatcga
    22261 tgtcttgaac attggtgaac ccgcaaatag ccgtccagtg acaatcaaag cagatgatct
    22321 acgttccact atccttgtat ccaatgattt cttcgcagtt tacaaatggg aaattactgg
    22381 aaaagttaac tttgaaaaga cagctgacta cagcttgttg agtgtcttgg ctggtcaagg
    22441 tcaactaact gttgacggga aaaactatcc aatccaaaaa gggagacact ttatcctacc
    22501 aagtgatgtt gaatcttgga ctctagaagg gcaagattta gaattaattg ttagtcatcc
    22561 ataaaaaaga aaggacctga gttcattact caagtccttt tgattacata aattgggcga
    22621 tgaagaccac gatgatgatt ggaatgacga aacgaagaag gaagagccag acttggaaca
    22681 gtccttgttt ccatgctctt tcatcgagat ggagttcctc cattgcaaga gcctttttaa
    22741 agatatagcc tgtaaaaagt gaaaggaaga gagctccaaa tggcatgagg agattggaaa
    22801 ccaagaagtc catagcgtca aagaaggctt taccaaaaat gtgaacatcc gccatgacac
    22861 cgtaagatag ggctgaagga atgccaaaga caaaggtcaa aattcctaaa ataacactcc
    22921 atttagcacg cttgctgttg tcctgattgg tgatattgtc tacattgatt tccagcataa
    22981 cgacagaaga agtgacagtc gcaaagagga agaggacata gaaaatggtt ccaaaaggca
    23041 tcttgtcaaa gagttgaggc aagacgataa agaccaagct cggtccccct tcaatattca
    23101 gtctgaaggg ggaccgagct tggaaaatgg ctagacctgc catgatggat accgagatat
    23161 tcatggctac gatggagatt cttgactgga ccagattggt tttcttgtcc aagtaagaag
    23221 cataggtcaa catggctgta acccctagtg agagggcaaa gaaagattgt ctcagagcat
    23281 agaggagacc agcgctagtc agttttgaaa aatctggttt gaggaagtaa agaacccctt
    23341 ccatggcatt tggcaaactg agagagcgtt cgatgatgac gacaaagatg ataaagagca
    23401 ggggcatcat gactttcgaa gctctttcaa tccctttttg aaccccacgt gatacaatga
    23461 agatattcaa taggataaag gtcgcttgag ctcctagagc aatggctgga tttgaaatga
    23521 tcagacttcc tgcgaaacaa aatatggcat agtagttcta tgaatgatga agcaagtaaa
    23581 caactaactg atgcacgatt taagcgtctt gttggtgttc agcgcacgac tttt
//
LOCUS       DAVAZT010000034        23482 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVAZT010000034 DAVAZT010000000
VERSION     DAVAZT010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23482
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.034"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(1..319)
                     /locus_tag="VQT45_001270"
                     /pseudo
     CDS             complement(1..319)
                     /locus_tag="VQT45_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(395..796)
                     /locus_tag="VQT45_001271"
     CDS             complement(395..796)
                     /locus_tag="VQT45_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2359594.1"
                     /translation="MDSASIIAHTIHQKFNLKVPNYRQEEDWARMGLPITRKEIANWH
                     IKASQYYLESLYNLLREKLLEQPLLHADETSYRVLESDSQLTYYWTFLSGKSEKQGIT
                     LYHHDQCRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            complement(804..1109)
                     /locus_tag="VQT45_001272"
     CDS             complement(804..1109)
                     /locus_tag="VQT45_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase zinc-finger binding
                     domain-containing protein"
                     /protein_id="HET2359595.1"
                     /translation="MFPVETEEITYKRKKSKGKRQALLAQFDSEEVHHQVEESICSDC
                     QGDLKEIGATLQRQELVFIPAQLKRIDHIQHAYKCQACSDKNPSDKIVKAPIPKAPL"
     gene            complement(1096..1290)
                     /locus_tag="VQT45_001273"
     CDS             complement(1096..1290)
                     /locus_tag="VQT45_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2359596.1"
                     /translation="MKIIQQQSATIDSLTNALALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLNLFEEESPSEKDGDVPS"
     gene            complement(1366..1706)
                     /gene="tnpB"
                     /locus_tag="VQT45_001274"
                     /pseudo
     CDS             complement(1366..1706)
                     /gene="tnpB"
                     /locus_tag="VQT45_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(1687..1872)
                     /locus_tag="VQT45_001275"
     CDS             complement(1687..1872)
                     /locus_tag="VQT45_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359597.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(2176..3738)
                     /gene="guaA"
                     /locus_tag="VQT45_001276"
     CDS             complement(2176..3738)
                     /gene="guaA"
                     /locus_tag="VQT45_001276"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HET2359598.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            3880..4578
                     /locus_tag="VQT45_001277"
     CDS             3880..4578
                     /locus_tag="VQT45_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2359599.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(4621..5517)
                     /locus_tag="VQT45_001278"
     CDS             complement(4621..5517)
                     /locus_tag="VQT45_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET2359600.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLLIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(5526..6461)
                     /locus_tag="VQT45_001279"
     CDS             complement(5526..6461)
                     /locus_tag="VQT45_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HET2359601.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(6458..7183)
                     /locus_tag="VQT45_001280"
     CDS             complement(6458..7183)
                     /locus_tag="VQT45_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HET2359602.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(7267..7902)
                     /locus_tag="VQT45_001281"
     CDS             complement(7267..7902)
                     /locus_tag="VQT45_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HET2359603.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY"
     gene            complement(7904..8731)
                     /locus_tag="VQT45_001282"
     CDS             complement(7904..8731)
                     /locus_tag="VQT45_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2359604.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(8753..9089)
                     /locus_tag="VQT45_001283"
                     /pseudo
     CDS             complement(8753..9089)
                     /locus_tag="VQT45_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
     gene            complement(9090..9806)
                     /locus_tag="VQT45_001284"
     CDS             complement(9090..9806)
                     /locus_tag="VQT45_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HET2359605.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPVEVMDAIKEAGYHVLDLAHNHILDSQIEGVISMADII
                     EKAGITPIGVYTHEPRDQAPLVIKEVNAIKVALLAYSYGFNGIEQYIFQEDYNRYLSD
                     LNEDKIKAEVERAEKEADITIIMPQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSKTVEKDGDKKLIIY"
     gene            10329..10940
                     /locus_tag="VQT45_001285"
     CDS             10329..10940
                     /locus_tag="VQT45_001285"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET2359606.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEGIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            10985..11713
                     /gene="rlmB"
                     /locus_tag="VQT45_001286"
     CDS             10985..11713
                     /gene="rlmB"
                     /locus_tag="VQT45_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HET2359607.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFLNRL"
     gene            complement(11752..12663)
                     /gene="trxB"
                     /locus_tag="VQT45_001287"
     CDS             complement(11752..12663)
                     /gene="trxB"
                     /locus_tag="VQT45_001287"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HET2359608.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVKEIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(12729..12953)
                     /locus_tag="VQT45_001288"
     CDS             complement(12729..12953)
                     /locus_tag="VQT45_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HET2359609.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(13031..13774)
                     /locus_tag="VQT45_001289"
     CDS             complement(13031..13774)
                     /locus_tag="VQT45_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2359610.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILLLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(13774..14574)
                     /locus_tag="VQT45_001290"
     CDS             complement(13774..14574)
                     /locus_tag="VQT45_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2359611.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(14732..15088)
                     /locus_tag="VQT45_001291"
     CDS             complement(14732..15088)
                     /locus_tag="VQT45_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET2359612.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(15101..15613)
                     /locus_tag="VQT45_001292"
     CDS             complement(15101..15613)
                     /locus_tag="VQT45_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HET2359613.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(15613..16107)
                     /locus_tag="VQT45_001293"
     CDS             complement(15613..16107)
                     /locus_tag="VQT45_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2359614.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            16242..16688
                     /locus_tag="VQT45_001294"
     CDS             16242..16688
                     /locus_tag="VQT45_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HET2359615.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            16685..17332
                     /locus_tag="VQT45_001295"
     CDS             16685..17332
                     /locus_tag="VQT45_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HET2359616.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(17353..17934)
                     /gene="pdxT"
                     /locus_tag="VQT45_001296"
     CDS             complement(17353..17934)
                     /gene="pdxT"
                     /locus_tag="VQT45_001296"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HET2359617.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(17935..18810)
                     /gene="pdxS"
                     /locus_tag="VQT45_001297"
     CDS             complement(17935..18810)
                     /gene="pdxS"
                     /locus_tag="VQT45_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HET2359618.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(18962..20341)
                     /locus_tag="VQT45_001298"
     CDS             complement(18962..20341)
                     /locus_tag="VQT45_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET2359619.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKDKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            20636..21559
                     /locus_tag="VQT45_001299"
     CDS             20636..21559
                     /locus_tag="VQT45_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HET2359620.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGISPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            21619..22224
                     /locus_tag="VQT45_001300"
     CDS             21619..22224
                     /locus_tag="VQT45_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET2359621.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKTIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLTHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            22242..>23482
                     /locus_tag="VQT45_001301"
     CDS             22242..>23482
                     /locus_tag="VQT45_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET2359622.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRNFKFKFELEVLEIDEVPMF
                     NQDEKWDESFQLRFLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGAS"
BASE COUNT         6972 a         5279 c         4282 g         6949 t
ORIGIN      
        1 atacttgagg ctgtattcaa ttgcccttcc tagttttgaa cccgataaaa ctgactgacg
       61 ccggcaccaa gcaaagaaat cttccattag gttggagctc ttcttgacgt ttctgtagtc
      121 gttcatcagc tggcaaagcc tcccagtctc tttccaagaa aaataactga tcacaataag
      181 ctaaaccttt agctcctaag gatgatttat ccgcttgctt gggggtcgct tcaaaaaact
      241 tccttctcac atgcgcccaa catccaacaa gtgcagcttc ttccagttga cgataagctt
      301 ctagcggttc gcagtttacc aagcttagcg tcgccttgct cctaaacctt ggactgctat
      361 cgcataggca gaactagagg actaaagtcc taagttactg ccgcaacata tcacaatgca
      421 catagccaga ataatctcct aggaattctt gtactactga accacttcga cactgatcat
      481 ggtggtaaag cgtaatccct tgtttctctg atttacctga caaaaaagtc caatagtaag
      541 tcagctgact atcactttct aagacccgat aagaggtttc atctgcatga agaagaggtt
      601 gttctaacaa cttttctcgt aaaaggttat aaagggactc taaatagtat tgactcgcct
      661 tgatatgcca attagcaatt tccttacgtg tgattggtaa acccatccta gcccaatctt
      721 cttcttggcg ataattaggt accttcagat taaacttctg atggatggtg tgagcgataa
      781 tagaagctga gtcaatagtc tcgttataaa ggggctttag gaataggagc tttcacaatt
      841 ttatcactcg gatttttatc actgcatgct tggcatttgt aagcgtgttg gatatgatct
      901 atgcgtttta attgcgcagg aataaagact aattcttgtc gttgaagggt tgctccaatc
      961 tcttttagat ctccctgaca atcagagcaa atgctctctt ctacttgatg atgaacttct
     1021 tctgaatcaa attgggcaag aagagcttgg cgtttccctt tagatttctt acgtttgtag
     1081 gtaatttcct ctgtttcaac tgggaacatc tccatctttc tcagatggag actcttcctc
     1141 aaaaaggttg agttgtccag aggggcaaac acttttctca gaggattttc catagagctt
     1201 ttgagtcaga taagccactt gttcacgaag aagggcaagt gcattggtga gactatcaat
     1261 tgtagcactc tgttgttgaa tgattttcaa tcttcttcca tgggcttccc ctccttgttt
     1321 tctaccttta ttatactaaa aagaaagtcc tcatttcaat agaaatcacg actttctgat
     1381 ggatttattt ttggagtgat agaaaagtcc ttcataagcc agtctacttg ttcagatgtg
     1441 agagctttga catccttttc tgtactgggc caagtcagtc tgccgttccc aaagcgttta
     1501 tatagtagcc aaaatccttg accatcccag taaagggctt taaagcggta tttacgtcca
     1561 ccacaaaaga gaaaaacttg acctgagaaa ggatctaatt caaagtgggt tttaaccaga
     1621 taagccagtg aatcaatgcc ttgcctcata tccgttttcc cacatacgag atagacctgc
     1681 cctaggctag atagatgaat tgtcatagag caacacctta tccaaaagct gttctaccat
     1741 ttcgagattg agagattgaa aaaaacttac ttcaagcttg ccaatacgaa ttttaagcag
     1801 aatatcattt ctctttttag aatcaaaagg acgagattgt ggaatctcta caggaacaat
     1861 aggttgtggc attaaaatat cctccaatag ttttacttta ctaatagtat acaggaggaa
     1921 ctccatgaat gatagatacc ttgttatgac gcgattacta tattagaaag ttggctctct
     1981 aattaaatta attctcatta tatatatcaa aagaccgcag cttgaaaact acggtctaat
     2041 tttttgtcca aatgtaaacc acttggaact attattcaat ttattctttt tagtaaatgt
     2101 tcccgtttta atcccagtta cagtttttaa tcctctgtaa ccgttgattt tacaaagctt
     2161 ttaatttttt tgcgattatt cccactcaac tgttgcaggt ggtttacttg taatatcgta
     2221 gacgatacgg ttaacatgat ccacttcatt tacgatacgt actgagattt tttgaagtac
     2281 ttcccatgga attttggcaa aatcagcagt cataccatcg atagaagtga tagcacggat
     2341 tgcaatcgtg tagtcatatg tacgaccgtc acccataaca ccgactgaac gaacgcctgt
     2401 gttaacagtg aagtattgcc aaatatcgcg gtcaagtcca gctttagcga tttcttcacg
     2461 aagaatagcg tctgattcac gaacggtttc aagtttctct tcagtgattt cacccatgac
     2521 acggatagca agtcctggtc ctgggaatgg ttggcgccat acgatatggt ctggcatacc
     2581 aagctctgta ccaagagcac gaacttcatc cttgtaaaga gtattgagtg gttcaatcaa
     2641 ttcaaactgc atatcttctg gaagaccacc cacgttgtgg tgtgacttga tagtttgagc
     2701 tgtatccgta ccagactcga taacatctgt atataaagta ccttgagcaa ggaatttcac
     2761 atctttgagc ttgcttgctt cgtcatcgaa tacatagaca aactcgttac cgatgatttt
     2821 acgtttttgt tcaggatcag aaacgccagc aagtttgtca aggaaacgtt tagcagcgtc
     2881 tgctttgacg atattcaaac caaacttacc accgagcatg tccataactt gatcagcttc
     2941 gcctttacga agaagaccgt ggtctacgaa gatacagatc aattgatcgc caatcgcttt
     3001 ttggagaaga accccaacga cagatgagtc aacaccacct gatagaccaa gaaggacacg
     3061 tttatcaccg acggtttcac gaattttttt gatctgcatg tcaatgaaat tatccattga
     3121 ccagtcacct ttagccttac aaatgttaag ggcaaagtta cgaaggatat catttccgta
     3181 tacagaatga cgaacttctg ggtggaattg gataccgtaa atgtgtttat ctgggttttc
     3241 gatggctgcg tatgggcagt cagctgatgt acctgtacga acaaagtcag caggaatctc
     3301 agtaaccgca tcaccatggc tcatcaaaac agtctgttca tcaggtgttg attcaaaaag
     3361 cgctgatggt gtgtgagtta gggttgattg accgtattca cgatttccag catcacctgc
     3421 aggaacaact tttcctccaa gtttatgggt caataactgc ataccataac agattcccaa
     3481 aattggaatt ccgagttcga agatttctgg gtcaatatca aatgaaccat cttcatatac
     3541 agaatttgga ccacctgata gaataattcc tacaggattg acttcacgaa cttcagcagc
     3601 tgaaatttta tggcttttta gttctgaaaa aacaccaatc tcacggatac ggcgtgaaat
     3661 cagctggttg tactggctac catagtccaa tacgatgatt ttttctacat cttgcaaatc
     3721 agttgaaatg ttgctcatct ttttcctttc tcaaaagaaa tatcttttct caatattcta
     3781 tcacaaataa gggcgaatta ccaactaaac aaggcgaagt ttgacttttt ctagtttatt
     3841 ggggtacaat agagaaaaga tagaaatgaa gtgaaaaata tgctacctgc ttatatgaaa
     3901 atccatgatc agataaaaaa ggatattgac gagcaccgtt gggctattgg tgagaggctt
     3961 cccagtgaaa gagatttagc tgagcagttt gcggtcagtc gcatgaccct ccgccaagcc
     4021 gtatctctat tagtcgaaga aggcgtctta gagcgccgtg taggaagcgg cacctttgtt
     4081 tccagtactc gagtacaaga aaagatgcga gggacaacca gttttactga aattgtcaaa
     4141 tcccaaggta aagttccctc tagccagctc atttcctaca aaaaaaccat tcccaatgag
     4201 caagaagttg ccaagctagg aatttttcca acggacaata ttatccgaat ggagcgggtc
     4261 cgctatgccg accaagttcc cctagtttat gaagttgctt ctattcctga aaaattcatt
     4321 aaggacttta aaaaagaaga aatcacaagt catttcttcc aaaccttgca aaaacatggc
     4381 tatcgtatcg gcaaatctca acagaccatc tatgctcgcc ttgctaaaga aaagattgcc
     4441 cactatttgg aagttgaaaa aggacatgct attcttggat tgacccaggt ttcctaccta
     4501 gaagatggta ctgcttttga atacgtaaaa agtcaatatg taggcgaacg ctttgaattt
     4561 tatcttgaaa ataattagat taccacgcaa aaactctctg tcacggacaa agagtctttt
     4621 ttatttttct aagaataaat ctttcaaaga aatcaaagtt acagcaaaca atatcattgc
     4681 cataccaaga aaatcaatgg gataaaattg ttcattcatt attaagaagg caaagaaaat
     4741 cgccgatatt ggctcaattg aagccaacaa gcttgacttg accggtccta tcagactggc
     4801 tcctttaagg aaagctgtat aggcaaagac agtcccgata aggataatgc ctgcaaacgc
     4861 aaggagaaaa tcaagactag tcgggatatc ggcctgtaga acccctgtaa aaggaagggc
     4921 gaccaaacct gctatgacca ttcccacacc aatgagcaag ctgctccccc actttttaat
     4981 caaggctatg ggtaaaatga tatacagagc ataagtcaag gcagaaaaga gaccccagaa
     5041 cagaccagca ggtgtcatgg ataactggtc caactgccca tgtgttgcga tcaggaaggt
     5101 tcctccgatg gcgaatatga tggaaactat ctctcccagt gtcggtgcca ccctatcctt
     5161 gatacagcta taaattaaaa ttccgacagg acaaacatac tgaagcaccg tcgctgttcc
     5221 cgcattggtc tcctgaatag cagacagata ggcgaattgg ttgagaaaaa gaccaatcag
     5281 agcaaaaata agaagagaca gcaaactctt tctatccttt aaaaagacca gtattttatc
     5341 ctttgcagta gcataagcca agagcatgag aattccacca gcgattaaaa gacgcaagtt
     5401 ggtcaagacc agagccgaaa ttccgtgtgc cattaggtat tggccactcg ttcctgacaa
     5461 cccccaagca ataccagcca caactgttag taaagtccct tttaaactat ttgacatgtc
     5521 tctccttact cttctttgcg aatcaagttc atcacttgat tgcggtctaa tatccattga
     5581 gctctctcgt ccttttcata ggtacgattc gataggaaaa tagtggcttc ttgcttctga
     5641 cgattccaca tgataaaggt acctgtatag cccgtatggt ctagccaatc tccttccaaa
     5701 ttccatgcta aagaacgttc cttgtcatcc aaaggagaaa aattttgatt taagtctctt
     5761 gcaaaatcat ctgctaaata gtgttctaaa aagatttgta aatcctttat agtcgaaaat
     5821 aaaccagcac tcccagcatg tctacccagg agacgagcct tgggatcatg cactatgcct
     5881 gcctctacac ctctaactgt tggaacagca agctcaactg gcccaaactt ggtttccgtc
     5941 attccccaag gtttccagac ttgatccttt aaaatcacat ccaaatcttg attaaaaatt
     6001 ctttccaaaa taaagcccaa cagcaaaaaa tggacatccg aataaagaaa ggctggctga
     6061 cttcgtctgt tgagatgaaa catcgcttcc tttaattcag gggctgttaa aagatcacga
     6121 ttaggaataa aaggatcaag gtctgttgca tgagtcaaga gctggcgaat agtgatgtct
     6181 ggataatcac tctcaggtaa aaaatctatt accagtctat caatatctaa ttgacctatt
     6241 tcccacaaga aggtacaaac tgtgccaacc ccaacaacct tgctgacact agctagatca
     6301 taaactagtc ctgcctcagt ctgcaagcca tgctctgggt cactctggcc taaatagaac
     6361 tctgtccatt gattgtcctt aaaatacgca aaagaggctc cgggataaat tcctgcctcg
     6421 atttgttctt ctattttttt aataatcttg gtccacttca tacttcttca aaccacaatt
     6481 caacattatt tctatcttta ccaaggaaga atttttcaga cttaggaata aaatattcag
     6541 tagactcaaa cttctggcga agacttgcta tgtctaattc attgaccaag aacttgagca
     6601 tagataagtc ccaggtaacc gtattgtcca cagtcaaatc ctgcccctga gctggaataa
     6661 aatcaaggga tgccccaatt tcagatgatt ccaagaaact ttcgatatca gttgggagat
     6721 gtaattccat agaaatctca aatttactta aagaaattga tgccaaatct gtttgaaatt
     6781 caggcttttc tcctacttct actagacttg ctctgtcatc ttccgcatga atcaaaatca
     6841 aatcatcttc tggtgagaaa atttcaaaag cgtagccatt ttgaccttta tataatcgat
     6901 gaatcgaatc tgttttagat aagattcctt caatttctaa gggattttcc accttgacaa
     6961 tcaatctagc tagttttttt cttccctcta ccttacgagt acgcatactg ggagcttctt
     7021 ctaaaaccag cttttcaaga cccgtttggt cacctagtga cagaaaggcc gattcttcta
     7081 acaaggcctt cattccaagg gtttcaatat aaaatgtttc atttaatttt ctattattag
     7141 cttttaaagt aggaataatc cgtacaatct gatttacatt cataaattcc tccgtcactt
     7201 tttattttaa aggattttag aattttttac aagatattat gctcaaattt aacattattt
     7261 agctatttag taaagatagt ctttcaagga ttttgacaaa gcctgataac cagcaatact
     7321 gaggtgcagt ccatcagttg tatattcttt tttgagttgg cctgcttggt ctgtcaaaca
     7381 atcaaatact ggcacaaatt ccacctgcat ataggcagat gcaagctctt gataggcttg
     7441 attccagttc tgaatttttt cattcgagcg gatatagact gcctgctggt actcctctcc
     7501 ctcattgaca ggcaaaatgg aaagcaattt aatctctgtc aatggataat cgcgagcaac
     7561 ggattgaatg atagcttcga gattattgag agcctcattc acaggaacat cctttccgat
     7621 atcatttgtc ccaatcagaa gaaaaatttt atctactgct ccaccatata gatgagcatc
     7681 aagattctct agtaacagtc ctgtctgata gccacgaatt cctcgattga caatcgtctt
     7741 tgaagtccca aatagctcct gtagaggata atactcgaca atggaatccc caataaaaag
     7801 aatgtttggt tctacaacag aaatgtgatt taggtgacga tacttagttt gaattttttc
     7861 ttgttccttt aggagccaat tttctaataa ctgtactgcc acttcattct cctttttcta
     7921 accagttttc caagacttga taaactcctc cttggctgtt ggctggtgct agagcagtcg
     7981 ccacagcttt ggctttctca tcagcatttt ccatcgcata ggcaattcca gccatttcaa
     8041 gcatttcaac atcattttca ctatcaccaa aagccatgat ttcttgggat ttcaagtccc
     8101 agcgcttgag taattcctcc aagccccatg ctttatgaat cccagcttgg aggatatcaa
     8161 tgcaaccata gccactggat acagctcgga cacggccatc aaagagagca ttgatttctt
     8221 ccaaaaccga actcaaacgt tcctcaccaa caaccatgct catcttgagc acaccaccaa
     8281 agaggtcaga tgttaattca tccacaaatt gcatccgttg gtagaatttt tcaatcattt
     8341 ctggagtcat aaaactttca agatctgtaa aaatcgtacc ttccttgaca aaatcaccct
     8401 tcatccccgt tacaacaaac tggtcctgac acgctcgacc cttgaaatga gccaaagcct
     8461 tgttgacaat ggcgtcatcc catgtctgag cctgaatcaa ttcattgttt tcaaaaatac
     8521 gagcgccatt agcaacaacc agaaccactc gatccaccaa gggactcagt agttgtctca
     8581 tgcggtgaat ttcattgccc gtcgcaatga caaaacgaat gcccctttga tccaactgat
     8641 ctaaaatctt ttccaatcgt gggagatcaa gctgacccct agcatccagc aaggtcccat
     8701 ccatatctgt cgcaattacc ttaatcatca tttactttcc tctggattca agctaatacc
     8761 acttcaatcc cacatgttca ttcatttctt tataggctgt atcaattcgt tccttagtcg
     8821 cttcatctaa ctggtcacga tgactgccac ccctctataa aatcttccaa aatataagtt
     8881 tggtaatgat acaagggata tccttctggt gaaaaggttc cctttggtgt tcgattgacc
     8941 caagtaggat gagctttagc tgttccgata gttgtttttc catccttctt cttgatggtg
     9001 acatccatga gaacaccacg ttcagtccac ttagcattct cttcatctcc catagattca
     9061 atccgttgat tggaaatgaa gttccccatt taatagataa tgagtttctt atctccatct
     9121 ttttcaaccg ttttagatgg ttcaacaacg tgaggatgcc ctccaaagat aatatccgct
     9181 ccccaatcga tcatcttgtg ataaagagct ttttgttctt cagttggttc caatcgatac
     9241 tcaacaccca tctgaggcat gataatggtg atatctgctt ccttctctgc ccgttcgact
     9301 tcagccttta tcttatcttc gtttaaatct gaaagataac gattatagtc ttcctgaaaa
     9361 atatactgct caattccatt gaaaccatag gaataggcta acaatgcaac cttgatagca
     9421 ttcacttcct taatgaccag cggagcctga tcacgtggtt cgtgcgtata aactccgatt
     9481 ggagtgattc cagctttctc aataatatcg gccattgaaa taactccctc aatttgcgaa
     9541 tccaaaatat gattatgagc taaatccagc acatgataac ctgcttcctt aatagcatcc
     9601 ataacttcaa caggagcatt aaagagaaga taacccgcta aataatgatc cttattaatg
     9661 gttccttcaa aatcaccaat agctaaatct gcttgcttga gccaaggagt cacatactca
     9721 aaattttcat gaaagtcata ggtaccgtct tcttttttag ctgaaaagaa aagtccatcg
     9781 tggtagagca aatccccgtg ggccataatt ctggcagttt tttcctcttc ctactcctga
     9841 gacttttgct tagtcccctc ttgagaaata gtatctcgtt tttgactagt caagggattc
     9901 cttggaagct ttcaaacaac aagaccaagc ccattgataa accaactgct agcaagagta
     9961 tcgccacaaa tcccttattg ctccacttgc gataactcct aaaaagttta ccaagccctt
    10021 cataaaacga aaagctaaac caccctgatt tcgattttgt cttctttgta tcttcattct
    10081 ccctactttc ttatgcaagc cttttctttt tattatatca cagataagta tttctttcac
    10141 aattgaattg aacttcccat ctattttcta taaatcctaa atgccataat gctttcaatt
    10201 cttgtcattt tgtgatatca tgtagaggta atgaaaggaa atgaactaat ccacagtggc
    10261 ttattccaag tataccactt gggctttggc agtagttaac tgcactaaac ataatataag
    10321 gagagaaaat gtctgcaata gaacgtatta caaaagctgc tcacttaatt gatatgaacg
    10381 atattatccg tgaagggaat cctactctac gcgcgattgc tgaggaagtc actttccccc
    10441 tatctgacca ggaaatcatc ctaggcgaaa agatgatgca attccttaaa cattcccaag
    10501 atcctgtcat ggctgaaaaa atgggactcc gcggtggtgt tggactggct gctccccagt
    10561 tagatatctc aaaacgcatt atcgctgttt tggtacctaa tattgttgaa gaaggcgaaa
    10621 ctccacagga agcctacgat ttggaaggca ttatgtacaa tccaaaaatc gtctctcact
    10681 ctgttcaaga tgctgctctt ggcgaaggag aaggttgcct gtctgttgac cgtaacgtgc
    10741 ctggctatgt tgttcgccat gcccgcgtta ctgttgacta ctttgacaaa gatggagaaa
    10801 aacaccgtat caaactcaaa ggctacaact ccattgttgt tcagcatgaa attgaccaca
    10861 ttaacggtat catgttttac gatcgcatca atgaaaaaga cccatttgca gttaaagatg
    10921 gtttactgat tcttgaataa agaaaatccc gttgcaagac ggggttttgt gttataatag
    10981 aggcatgaaa acaaatgata ttgtctatgg tgtccacgcc gttaccgaag ccctccttgc
    11041 aaatacagga aacaaactct acctccaaga agatctccga ggtaagaatg ttgagaaagt
    11101 caaggaacta gctacagaaa agaaggtgtc catttcttgg acatcaaaaa aatctctctc
    11161 tgagatgact gaaggtgctg ttcatcaagg ttttgttcta cgagtgtctg aatttgccta
    11221 tagcgagcta gattacatcc ttgcaaaaac acgccaagaa gaaaatccac ttctattgat
    11281 tctagatggt ctaaccgatc cccataatct gggttctatc ttgcgaacag ccgatgcgac
    11341 caatgtttca ggtgtcatca ttcccaagca ccgtgctgtc ggagtaactc ctgtcgttgc
    11401 caaaacagcc acaggtgcta ttgaacacgt tccaattgcc cgagtgacaa acctcagtca
    11461 aaccttagat aaactcaagg atgaaggctt ctggaccttt ggaacggata tgaacggtac
    11521 tccttgccac aagtggaata caaaagggaa aatcgccctc atcatcggaa atgaaggaaa
    11581 aggcatctct agcaacatca aaaaacaggt cgatgaaatg attaccattc cgatgaatgg
    11641 acatgttcaa agcctcaatg ccagtgttgc tgcagccatt ctcatgtacg aagtttttct
    11701 aaatagacta taaaaaagtt tccagtcatc tgattggaaa cttttttatg attaactatg
    11761 ttctgtgata aacttgtagg cttcttgacc agcgatagct ccatctccaa ctgctgttgt
    11821 tacttggcga aggtctttca agcgaacatc tccaactgca aagataccgt cgactgcagt
    11881 cttcatgtgg ctatctgtca caatccagcc tgcctgatct tggatattca attctttaac
    11941 aaaatcgcta agagggtcca aaccaacata gataaagaca ccaccgaagg cttgctctgt
    12001 cacttgacct gttttcacat tttcaaaaac gacagattct actctgtttt cacccttgat
    12061 ttccttcact acagaatccc agataaagct gattttttca ttcgcaaagg cgcgatcttg
    12121 taaaaccttt tgggcacgaa gttggtcacg acggtgaaca atggtaacag tcttagcaaa
    12181 acgagtcaag aagagggctt cttcaacagc tgaatctcca ccaccaacta ccaataaatc
    12241 ttggtcacgg aagaaagcac catcacacac agcacagtaa gaaacaccac gactgttcag
    12301 ttcttcttct ccaggcactc ccaaaggacg gtgtttagaa ccagttgcta cgataactgt
    12361 acgtgtttca tatgtttggt catcagtcat cactttctta aaatcaccat ggtcttcgac
    12421 attttcaaca taaccataaa tgtgctcaac accaagattt tcaagtggtt caaacatctt
    12481 ttcagccaat tcaggtccac taatattagc gtatcctggg taattttcga tatcagatgt
    12541 attattcatc tgaccacctg gcagaccacc ttcaatcaaa gctactttta gattgcttcg
    12601 agcagcatac aaggccgcag tcatccctgc aggtccagca ccgataataa tagtatcgta
    12661 catatagatt ccttctttct tgttgtaact atctttattc taactctttc ttgtcaatca
    12721 cgcaaggatt atgccttgaa aacaagaatt aaactcataa ccgcaaagga taatactggg
    12781 acaaccaaga ctccaatcat aatcatatca tagagatggg cttggcgagc cctggctgtc
    12841 ttatcaactc ccgacatggc tctcagacca atccaaatcc ctaaaaaaat cagaacaagg
    12901 atggtggtca agatcaaact ctcgaaatat aaagaaaata gttgcagtag catgatttct
    12961 ctcatttcta tcttttttaa agagtaaact cagctagtcc aactaactga gttttccttt
    13021 atctattata tcaaatataa gtccgtttgt aactagcgaa gaattctttt gtccgctctt
    13081 ctttaggggt gtggataatc tcatccggag ttccagactc gatgattttc cccttatcta
    13141 ataagagaat tttatccgca acttgggcta caaaggacat gtcatgactg accaaaatca
    13201 tggtctgacc tgacttagca gcatctgcaa tagacttttc tacttcaccg accaattctg
    13261 ggtcaagggc tgaagttggt tcgtctaaga gcaaaacatc tggtttcata gcaagcgcac
    13321 gcgctagggc aacccgttgc ttctgtccac ctgataaatg gcgaggataa tggttttcac
    13381 ggtccgaaag cccaacctta gccaactctt ccttggcaat cttagtcgct tcttggtcag
    13441 ataatttctt gacaacaacc aagccttctt tcacattatc aagtgctgtt cgacgttcaa
    13501 ataaattaaa ctgttggaaa accatagaca acttacggcg tagggcaagg atttcttctt
    13561 gagtgatttt agaaaaatca actgaaaaac catcaatctg aatagagcca ctgtcaggtg
    13621 tttcaagata attgagactg cgaagaaagg ttgattttcc agctcctgaa gaaccaatca
    13681 aggctacaac ttcccctttt tgaatatcca agttcagatg atccaagaca gtctgtcctg
    13741 aaaaggattt gcttaaattc gaaatcttaa tcattaacga aggtctcctt tcacatctgt
    13801 ttgcactgta tcaggtgcag aaatagccat ttttctctcg atgaaacgac cgaggctttc
    13861 aattccgata ttgactaccc aataaacaag ggcaacagag atgaagcgtt caaaatagcg
    13921 ataatcagct ccacctagaa tctgagcttg ggcaaagact tccacaacac ccgcactaaa
    13981 agctagagat gttcccttgg tcaaaccgat gagggaatta atcaaggttg gagtagctac
    14041 caccgctgca ttaggaataa tcactcgtcg ataaacttgc gctcgggtca tacccagact
    14101 gcgcgccgcc tcaatctcac caggattaac tgagagaatg gctgcacgaa tggtttcact
    14161 agcataagct gcctcattaa aggcaaaagc gacaatcgca aaagctgcag ctggaatcgc
    14221 attgatattg agaccagttc cccattgctg attgagggct ttcaaagcca aagggattcc
    14281 gtagtaggtc aacatgagtt gcaccaaaat cggtgtccct tttaagaaac taacaaagaa
    14341 ggcctgcaag ggatataaaa tcttgacacg attgatcttc acaatggcaa aaagaagcgc
    14401 caaaaccaag ccaaaaaggg caccaccaat tgtcaacata attgttgttg gaagttgttg
    14461 gacaattcta gggattccat caaagaccga acgtaggcta aacagcttgc catccggaat
    14521 caattgcatc aagttttggt accaatctga tgctaaaatc gttgtaacat tcataaaaac
    14581 atcctcttct gataatgatt cattctacca tgcttctgcc gtcaatgaaa ttatttgcta
    14641 cggtcagata cagactttgt ctacctacta gtttatcata ctttgaaaca gggaagttat
    14701 atattttatc tatcaaagag atagataaaa actatttcag tcccagttct tcataagatt
    14761 ttcgataacc gatttgctta acagttccat tttctactaa aatgggccgt tttaacaaca
    14821 taccgtcact tgctagcaac tcagccgctt cttggtttga caaacttcct accttatctt
    14881 ttagccctaa ttcacggtat ttgataccac tggtgttgaa aaattgcttc aattcaaatc
    14941 ctgaggtttc tagccaattc aaaatgactt cttggctagg tgtttcttcc acgatatgga
    15001 cggctttata gtccacacct aattgattta attcttgttt tgctttttta caagttgaac
    15061 atttggggta ttcgataaat tctaacatgt gcttctcctt ctatttgttt atatctttaa
    15121 aatctacgcc ttcatgctcc aagagccaag ctttcttttc cactcctgca gcatagcctg
    15181 tcagacgctt gcctgctccc aacacacgat gacaaggtac taggatagac caaggattgc
    15241 gtcccactgc tccaccaatt gcttgagcag aagccacttg caggtcttga gcaatttgtc
    15301 cataggtcac tgtctgacca taaggaatgc cctgtaaata gtcccaaact ctcttttcaa
    15361 aattcgttcc gattggcgcc aagagcaagt tggataaatc ctgaggcttg cctttaaagt
    15421 aatcatctaa gcaagcaata actgggtcta aaataggatg actaacaact tcttctatcg
    15481 tttcatctcc tagtcccctc tcaaaatgct tctgctcctg aacccaaatt ccatacaaat
    15541 aatggtcatc agctacaagt gatagaatac caattggtga ggagtagagt atttttacat
    15601 acttcttttg cattatttct ttaatttttg ataggccaag cgttcgccat ctactggcac
    15661 cttaccaact tgtttaaaac caagtttttc aaaaatatgt tgcataacct tgttttcagc
    15721 atgcgtatct gagcgaaaat caagataatc aaaaccttca atcaagccct ctaagaaggt
    15781 ttgagcaact ccttttccct gcacatctgc tgccacagca atacggtgaa agactagata
    15841 ctctgactct ccagcttgcc agtttccctc ataaatagct tcataggcct cctctggact
    15901 cttggtcaca gcagcatagg ctagcagttc tccctcttcc aaggctacgt aggcttgccc
    15961 tgagatgata tcatcgataa taacatctgc atttggatag ccattttgcc actggtcact
    16021 accagcatct gctaaacatt ttttggcatc ctccatcacc tgcatgatgg catctacttc
    16081 atttggaaaa gctaaacgaa tttccatctt ttttcctcat ttctgactag tttctcccat
    16141 catagcataa tttaagtatt tctacaagca gttaaaactt gactttgtgt ttttgttatt
    16201 ttataatcta gttatcaaaa ctatataaaa aggagttgaa aatgaaaact accttttcct
    16261 acccaaaatg ggcagaaatt ccaaacattg acctctatct ggaccaggtt ttgctctatg
    16321 tcaatcaggt ctgcgcccct atctctccta ataaagacaa gggcctaaca gcatctatgg
    16381 tcaacaatta tgtgaaaaat ggttacctga caaagcctga caaaaaaaaa taccaacgcc
    16441 aacagattgc ccgtttgatt gctatcacaa ccctcaagtc tgtattttct attcaagaaa
    16501 tagcccagac acttaatact ctacaaactc aagcaagttc agaccaactc tacgatgctt
    16561 ttgtggacta catgaaccaa ggaattgacc cagctaaccc tattatccaa accagctgcc
    16621 aaaccgtcaa actctatcat caaactctag acttaatcga tcatactcaa gaggaggtaa
    16681 tccaatgaac actagtctta aactcagcaa acaactcagt tttggagagg agattgctaa
    16741 tagcgtgacc catgctgtgg gtgcagtcat catgcttatc ttgctgccta tttcatccat
    16801 ctatagttat gaagcacacg gatttttatc ctctatcggc gtttccattt tcgtcatcag
    16861 tctctttctc atgttcctat catccaccat ttatcactct atggcctatg gttcgaccca
    16921 caaatatgtt ttgcgaatca ttgaccattc tatgatttac gttgccattg ccggctcata
    16981 cacgcccgtt gtcttgacct tgatgaataa ctggtttggc tatctgatta ttgtcatcca
    17041 atggggaacg accatctttg gtattctcta taaaatcttt gctaaaaagg tcaatgagaa
    17101 atttagcctt gctctttacc tgattatggg ctggttggtt ctggctatca ttcctgccat
    17161 tatcagtcaa acgacacccg ttttctggag tctcatggta actggcggac tctgttatac
    17221 agttggagct ggattttatg ccaagaaaaa accttatttc cacatgattt ggcatctctt
    17281 tatcctagct gcgtccgcac ttcaatacat cgctattgtt tattacatgt aaaaaagttg
    17341 agaaattcaa tctcaacttt tttctttaca catattgata aagtactggt gcaagcgcac
    17401 atcatcagtc aattctggat gaaaagaact taccaacata tttttttctt gggctgcaac
    17461 aatttgattg ttcactgttg ctagaatttc tacaccctca ccaacactac tgataatcgg
    17521 accacggata aaggtcattg gaatcttgcc aactccctta cattctgctt ccgtgtagaa
    17581 acttcctaat tggcgcccat aagcattacg ctcgaccacc atatccatag ttcctagatg
    17641 actctctttc tgagaagtga tttccttagc cagcaaaatt aagcccgcac aggtcccaaa
    17701 cactggtaag ccagatagaa tggcttctcg gatgggaagt agcatgttct ggtcacgtaa
    17761 gagcttgccc atggttgtag actcaccacc aggcaaaatc aaacccgaca agtcactctg
    17821 atcttgctga aaatcatcta gatttctgag ttctacactc tcgacaccta attgatctag
    17881 cacttttgca tgttctgcaa aggccccttg caaggccaat attccaattt tcatctattt
    17941 tcctcgttca gccatgagaa tttggatttc attttcatta ataccaacca tggcttctcc
    18001 taaatcttca gagatttgag ctaggatttg aggattacgg aagttagtca cagccttaac
    18061 aatggcactc gctcgtttaa caggatctcc tgacttgaaa atacctgaac cgacaaagac
    18121 cccctctgcc cctaattgca tcattaacgc agcatctgct ggcgttgcaa cacctccagc
    18181 agcgaaattt acaactggca attttccatg ttcatgaaca tattggacca attctacagg
    18241 gacttgcaaa tccttggcag caacataaag ctcgtcctca cgtaagtttt gaatgcggcg
    18301 aatttcctga ttcatcatac gcatatgacg aacagcttgg acgatatccc ctgtccctgg
    18361 ttctcctttg gtacgaatca tggaagcacc ttcagcgata cgacgcaagg cttcacccaa
    18421 atccttagca ccacagacaa aaggaacttg gaattctttc ttgtccacat ggaaacggtc
    18481 atcagctgga gatagaactt cactctcgtc gatataatca atttcaatag cctctaaaat
    18541 ctgagcttca acaaaatgcc cgattctgac cttagccatt actggaatac taaccgcttc
    18601 ttggatttcc ttaatcatct ttgggtcgct catgcgggaa actcctccag ctgcacgaat
    18661 atcagccgga attcgttcca aggccatcac agctgccgca ccagcagctt ctgcgatacg
    18721 agcctgttca ggattctgca catccataat aacaccaccc ttgagcatct gtgccaagtt
    18781 tttatttagt tcataacgat tttcagtcat ttgttttatc ctcatcattt gtattggtag
    18841 ctaccttttc attttaagtc agaacagaat gaagcacaag ataaaaaaac tataattgta
    18901 tggggacaga ttggctaaaa actatctgac cttaacttaa ggccagatag ctcattcatt
    18961 tttatttttc agccgtaagg gcagccattg tgatgtagtt gtatggttta ttgaagtgtg
    19021 gcaagaagaa gaggtctgtc aatgccaatt tatcaattgt cacatgctct tggatagcaa
    19081 gtgagaacat gtggattccc atgctaattg caatatcatg tgaaaccatt tgggcaccaa
    19141 gaatttcacg gctatctttg tcaaagacaa tcttaattgc tacttcatgg ttgtcatgtt
    19201 tcatgaattc tggtttttga agatcgttaa agcctgtttc agttgcgttg taaccagcag
    19261 ctttcgcttt ttcaagagtc aaaccagttg aaaccatgtg aagaccgtag attgagatac
    19321 catttgaacc ttgaacaccg attccttcca attcatgtcc acaagcgttg taggcaccaa
    19381 cgataccagt gcgaacagca tttgaagcaa gagcgatata gcttgtatct ttacgagcat
    19441 tgtcataaac agtcgcacag tcaccaacag cgtaaacgcc tgggatagat gtttcttgtt
    19501 tcttgtctac aaggaaggca ccgttgcgga agagttcgat cttaccatca gcaagggctg
    19561 tgtttggacg gaaaccaact gcaaggataa ccatatccac gtcaaagctt tctttgtcag
    19621 taatcaagcg ttcaacttta ccatcacctt cgattgcttt aacagtttga cctagagcca
    19681 agcggatgtt gtgatcttcc aagttcttcg ccatcatttg tgtgaagtct ttgtcatagt
    19741 aaccgttcaa gacagtatca acgatatcaa caaggacaac ttcttttcca agacgttcaa
    19801 aggcttcagc aagttcaaca ccgatgtaac caccaccaac aacggcgata cggtcgagat
    19861 gttggctctt gtcagaaagt ttattgataa cttcttcagc attttggtac aatttcacga
    19921 attgtacgtt ttcaagagtt gctttaaatt cgcggtttcc tttaacaatt tcaacacctt
    19981 cgattggtgg caagattggt gtagaacctg tagcgaaaat caatttctcg tatgattctt
    20041 tgtgttcttt tccttcaact tctgctgtaa ccactttgtt atcatagtcg attgaaagaa
    20101 ctggtgaatt catataaacc ttagcacctt tagcttctaa tttgtcttta tcagaataga
    20161 acaagccttc agcaccgtca atttgttcac caatccaaag agccattcca catcctagga
    20221 aagagatgtt agagttttgg tcaaatacaa caatttcgtt ctcatttcca aaattatcca
    20281 acatggtatt gatacatgct gtaccagcgt ggttagcacc gactacaacg attttactca
    20341 taaaaaattt cctgccttca ttctaaattt actttactag tataccattt accgttagcg
    20401 tttacaaggg ggggactatt atttcagcat tttttatcaa aaataattcc ccatttatcc
    20461 tgttttcaag cctcatgaat tttatgagca tatttcttga ctttttccaa attttgtttg
    20521 tgaaaattct aactttatgg tattataata acatgaaaat aaaatgtaag ggcttcaatt
    20581 tagatgatta tttgatattg caacttattt tctataagag aaaggagttg gtagcttgac
    20641 tcttcgttca cattctgaac ggctaatggg gactactatc actatttcat tagtggatga
    20701 gcaagccgat atctttctcc aaaaatcctt tgacttgctc aaagagcttg aataccgctt
    20761 caacgccaat agtcaagaat ctgagttgat ggaaatcaat tatcaagcag gaatatcccc
    20821 cgtcacagtt catccagacc tgtttgagct gatttcactt gggttagagc atagcctagc
    20881 gctctctagc cacctcaata tcagcattgg tcccttaatt caaacctggc gtatcggttt
    20941 ttcagatgcc aaggtcgccc agcctcaaga aattgaatcg gtgctgcctc taatcaatcc
    21001 tcatggtatc gagttagatt cttctacttc tactgtgttt ttaaaacaga aaggaatgaa
    21061 gatcgatcta ggttgtttag ccaaaggata cagtgcggat aaggttgccc aatttcttag
    21121 gaaagagggg gtgacttctg ccttgatcaa tctgggaggg aatatcctga ccattggaaa
    21181 aaatcaggca agaggggata acccatggca aatcgggatt caagacccag ccaatcctag
    21241 gggaaatcat ttaatgacca tccctgttgt caataaatct gtcgtgactt caggcattta
    21301 tgaacgtcac ctgaccgtcg atggacaaga ttaccatcac atttttgaca gtcaaacagg
    21361 atatcctgtt gaaacggaac tagcgagtct aacaatcatc tctgataaat cagtcgatgg
    21421 cgaaatctgg acgactcgac tctttggaga aagacctgct tctatcctct ggcaagtcga
    21481 aagtttggag ggcatcgaag tcatcctcat cgataaagaa ggccacctaa gctgttcttc
    21541 aggaattcct actctataga gacaactgtt tcaatggaat tttaaaattg tattatgtaa
    21601 aaagagaaag gaaatatcat gttaaaactt attgctattg ttggaacaaa ttcaaaacgt
    21661 tctacaaacc gtcaattgct tcaatacatg caaaaacact ttgctgacaa agctgaaatt
    21721 gaacttgttg aaatcaagac cattcctgtc ttcaacaaac cagctgacaa gcaagtacct
    21781 gctgaaatat tggaaattgc tgctaaaatc gaagaggcag atggcgttat tatcggtact
    21841 cctgagtatg atcactctat tccagctgtt ttgatgagcg ctcttgcttg gttgtcttat
    21901 ggtatttacc cacttttgaa caaaccaatc atgattacag gtgcttctta cggtacgctt
    21961 ggttcatctc gtgcccaatt gcaacttcgt caaatcttga atgctcctga aatcaaggca
    22021 aatgttcttc cagatgaatt cttgctcaca cactctcttc aagcatttaa cccaagtggc
    22081 gacttggttg accttgatgt tatcaagaaa ttggatgcca tctttgatga cttccgtatc
    22141 ttcgtgaaga ttactgagaa attgcgcaat gcgcaagaat tgcttcgcaa agatgctgaa
    22201 gactttgact gggaaaattt gtaagatagg agaccgaaag aatgaaattt gttggacttg
    22261 ttggatcaaa ctacgatcaa tcatataacc gcaaactctt ggaatttatc cgtcgcaatt
    22321 tcaaattcaa atttgaatta gaagtacttg aaatcgacga agttccaatg tttaaccaag
    22381 acgaaaaatg ggacgaaagc ttccaattgc gtttcttgta taacaagatt acacgtgctg
    22441 atggtgtcat tatcgccact cctgagcaca accacactat ctcagcttca ctcaaatctg
    22501 tacttgaatg gctttcatac gaagttcatc catttgaaaa caagcctgtt atgattgtgg
    22561 gtgcatcata ctatgaccaa ggaacatcac gtgctcaagt tcaccttcgt aaaatccttg
    22621 atgctccagg tgttaatgcc tacacgcttc caggtaacga attccttctt ggtaaagcta
    22681 aggaagcttt tgataacaac ggaaatatca ccaacgaagg cactgttaaa ttccttgaaa
    22741 cttgcttaga taactttgtt aaatacgtag gagtcgtttc gaaattgaaa aaaccaaaac
    22801 caatcgaatc agaagacttg gattgtggaa aaccaatcgc tacaaccatc acagaagttg
    22861 accctgacga tccagaatgg gtagaaaaag ttgcagcaat cactggtgct gtttctggtg
    22921 atacctatgt caaattggac cacggtatcc taacagttaa ccaaattgat atgttcttga
    22981 aagctatgcc atttgaattg acatacgctg acgacaacaa ccaattcctc tactacaaca
    23041 acgctcacca agatccagac actatgttcg ctaaacgtgt accacctcaa tcaggtagcc
    23101 gtatgtcgac tgttcatggt tctcttccac cagcacgtat gaagaacgta gagtgggtta
    23161 tcggaacact tcgcaacgga aaccaagaat acgtccgtac gatcgttcca ggttctcctg
    23221 caggtgttat caacactcac aactaccaag caatgtacta tcctgatgga tcatacgctg
    23281 gtatcaatga aatcgtcttt aacttccaac catggcttga ctggtaccta aaagagactg
    23341 gtcaacgttt ggtgggtggt agcggaccat ttgctcctgc tgccggaggt catggagacg
    23401 ccgatgctac ttctggcgct tctgattcag gggatgctgg aggccacggt ggtgacgcag
    23461 acgctacagc cggtgcaagt ta
//
LOCUS       DAVAZT010000035        22996 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVAZT010000035 DAVAZT010000000
VERSION     DAVAZT010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22996
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.035"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(20..667)
                     /locus_tag="VQT45_001302"
     CDS             complement(20..667)
                     /locus_tag="VQT45_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET2359623.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KQTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIRLPAKLES"
     gene            complement(776..1294)
                     /locus_tag="VQT45_001303"
     CDS             complement(776..1294)
                     /locus_tag="VQT45_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HET2359624.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(1521..2390)
                     /gene="rsmI"
                     /locus_tag="VQT45_001304"
     CDS             complement(1521..2390)
                     /gene="rsmI"
                     /locus_tag="VQT45_001304"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HET2359625.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGTSAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQDVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(2393..2710)
                     /gene="yabA"
                     /locus_tag="VQT45_001305"
     CDS             complement(2393..2710)
                     /gene="yabA"
                     /locus_tag="VQT45_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HET2359626.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(2750..3640)
                     /locus_tag="VQT45_001306"
     CDS             complement(2750..3640)
                     /locus_tag="VQT45_001306"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HET2359627.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(3637..4275)
                     /locus_tag="VQT45_001307"
     CDS             complement(3637..4275)
                     /locus_tag="VQT45_001307"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HET2359628.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            complement(4495..5292)
                     /gene="proC"
                     /locus_tag="VQT45_001308"
     CDS             complement(4495..5292)
                     /gene="proC"
                     /locus_tag="VQT45_001308"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HET2359629.1"
                     /translation="MKIGFIGLGNMGASLTKSVLQARPSDEILLANRSQVKVDAFIAN
                     FGGQTSNNEEIFEEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSEIFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            complement(5296..6558)
                     /locus_tag="VQT45_001309"
     CDS             complement(5296..6558)
                     /locus_tag="VQT45_001309"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HET2359630.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAVSFLPRLEQ
                     VLVADRKEAGLEPIQFRLDSKASQFVSGQAAQAQDFDTEFLDYILAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            complement(6568..7698)
                     /locus_tag="VQT45_001310"
     CDS             complement(6568..7698)
                     /locus_tag="VQT45_001310"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HET2359631.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMVEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRFQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(7781..9661)
                     /gene="cbpE"
                     /locus_tag="VQT45_001311"
                     /gene_synonym="pce"
     CDS             complement(7781..9661)
                     /gene="cbpE"
                     /locus_tag="VQT45_001311"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HET2359632.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSAYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKKWNNHWFY
                     LTDSGASAKNWKKIDGIWYYFNKENQMEIGWVQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTGGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SE"
     gene            complement(9664..10551)
                     /locus_tag="VQT45_001312"
     CDS             complement(9664..10551)
                     /locus_tag="VQT45_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET2359633.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLVLAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(10541..11002)
                     /locus_tag="VQT45_001313"
     CDS             complement(10541..11002)
                     /locus_tag="VQT45_001313"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HET2359634.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMFLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(10999..11907)
                     /locus_tag="VQT45_001314"
     CDS             complement(10999..11907)
                     /locus_tag="VQT45_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET2359635.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            11900..12097
                     /locus_tag="VQT45_001315"
     CDS             11900..12097
                     /locus_tag="VQT45_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2359636.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            complement(12149..12820)
                     /locus_tag="VQT45_001316"
     CDS             complement(12149..12820)
                     /locus_tag="VQT45_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2359637.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(12874..13095)
                     /locus_tag="VQT45_001317"
     CDS             complement(12874..13095)
                     /locus_tag="VQT45_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HET2359638.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            13367..14176
                     /locus_tag="VQT45_001318"
     CDS             13367..14176
                     /locus_tag="VQT45_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2359639.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(14357..15232)
                     /gene="aguB"
                     /locus_tag="VQT45_001319"
     CDS             complement(14357..15232)
                     /gene="aguB"
                     /locus_tag="VQT45_001319"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HET2359640.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKLLAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYNLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(15242..16327)
                     /gene="aguA"
                     /locus_tag="VQT45_001320"
     CDS             complement(15242..16327)
                     /gene="aguA"
                     /locus_tag="VQT45_001320"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HET2359641.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVV
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(16324..17451)
                     /gene="nspC"
                     /locus_tag="VQT45_001321"
     CDS             complement(16324..17451)
                     /gene="nspC"
                     /locus_tag="VQT45_001321"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HET2359642.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFESQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(17451..18710)
                     /locus_tag="VQT45_001322"
     CDS             complement(17451..18710)
                     /locus_tag="VQT45_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HET2359643.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMLD"
     gene            complement(18707..19567)
                     /gene="speE"
                     /locus_tag="VQT45_001323"
     CDS             complement(18707..19567)
                     /gene="speE"
                     /locus_tag="VQT45_001323"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HET2359644.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEYDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            19948..20537
                     /locus_tag="VQT45_001324"
                     /pseudo
     CDS             19948..20537
                     /locus_tag="VQT45_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(20503..21978)
                     /locus_tag="VQT45_001325"
     CDS             complement(20503..21978)
                     /locus_tag="VQT45_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HET2359645.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDDSVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            22685..>22996
                     /locus_tag="VQT45_001326"
     CDS             22685..>22996
                     /locus_tag="VQT45_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET2359646.1"
                     /translation="MQDNYTTKGKHLTIDSRRLIERWKKEGKSNREIASLLGKAPQTI
                     HTKIKRRTVRKCLGKGRFKEVYSADYAQQSYENNRKHSVKRSSVTKELKEKILHYHNQ
                     KF"
BASE COUNT         6746 a         5245 c         4095 g         6910 t
ORIGIN      
        1 tggtattatc aatcatgaac taggattcta gttttgcagg aagtctaatg taattctcaa
       61 gctgtgagtt cattatgatt tgtaaatccg atatatcttc agcagctaaa aacacatttt
      121 gaaatgttcc aagtccgttt tcaccaaaac tatattctct cttactatac ttactcttat
      181 tattctctat atagttagag tcaaggttct taacctcttg aagttcattt tctttacttc
      241 tgaggttaaa atcttttact tctgaagtta agttttttga cttctgtaag tcattttctt
      301 ttacctgaaa tatactcata aagtctttaa cataaatgat gttcggctta ccaagtccaa
      361 gccttactct ttcgatcagt cctattcctt tttttacatc aagctcatct aatgttttta
      421 tggcagttgg ctttgagata tttcttcttt tcataatttc ttcgacagta aaatagataa
      481 atactctgcc ttccttgtct atccagttat tcttaaatga cattcctgtc tgtttaagaa
      541 gtatggaata aaggataatt gcttctgctg ataagccccg aaattcttct ctatcaacta
      601 atatctccgg tacttttaag aagttaaatc tttccgcttc tctgttataa aaatattcaa
      661 agtccatgca agatcacctc ccttcttaaa aatttgcaaa gaaaaagacg atagtttttc
      721 ttctatcgcc tttggtaacc atttttatga aattttttaa agttaaaaat ataatttata
      781 atactatctt cttccatttt ctgattttag ttctgaaagt tccaaaaggt gcaaccgtat
      841 ttacatgaat aaacttatac acttcccaag tcgctgtttt agtcgcttca tcagcccact
      901 ttctcatatg cggttcaaat aattcttcct cactcaacga atcaatcatt gcagagatag
      961 aattaatatt ttcatttaat tttgctttca actcttgcag agataaatga gcgtaggtat
     1021 ctgtgaacca ctgatataat tcaccaagtt gattccattt aaatttatcc gatggtgttt
     1081 ttacttgaag cccctttctt tcatcttctt cccatttaag aaccaagttg gtccaaccaa
     1141 cctgataagc aaggttttct gctggagttc tgtcaacttc atcagctctc ttatctttta
     1201 aattttctgg aatattatca aattctaaaa tatatttctc aaatgttttc tctatctcag
     1261 cttttagttc ttctttattt tcgtatgttc gcaaaaaatc accttctttc tgatttatca
     1321 atcctttgat ttaaaatgac cttatttttc tatttatacc ttctaagaac gctataactg
     1381 ctgctccaaa catcggtatt ccgtatgggc ttaataaaaa acttaatacc aaagcttcta
     1441 taccaagtga tacatcttta tattatcatc actaattaag ttaaacagaa acagacagaa
     1501 ttattacatc ctgtctccct ttattgtttt tcttcccaat cgtggtaggc agcgtagagt
     1561 tgactcttat tccactggta aatcttagct acttccttaa tagcttgatt tttcttcatg
     1621 ccttgctgga tacgggcttg gatttctaag aacaagtcct cctcgtcttt ttcctccaca
     1681 tcctgactgg caccttcaac aataagaagg cattcgccct tgagtggcgt ttcagcgatg
     1741 ctttccagta attcagaaat tgtacctcgt tggtattctt catagatttt ggtcaattcc
     1801 ctgaccaaaa caaccgagcg gtcaccgtag acttctaaca tattttccaa cgtgtctgct
     1861 acacgatgag gtgattcata aaaaatctgt gtttcaggat aatctttttt agagccaaaa
     1921 aattgcttct gttgacctga ttttctcggt aaaaaaccgt aaaagatatg tggctgtggc
     1981 gctaaaccac tggcaatcaa ggcagaaatt cctgcagagg tacctggaac agtcacaact
     2041 gcaatttctt cctcaatagc tgccttaact aaatcatgac cagggtctga aatgctaggc
     2101 aaaccggcat cagagacctg agcaatactt tgccctgctt tcaagaaacc aatcaaatca
     2161 ggaatttttt ccttggcatt gtgctcatga aaactgatct gcttggtgga aatgtcaaaa
     2221 tgcttgagca aaagccctgt attgcgcgta tcctcagcag caatccagtc cacttctttc
     2281 aaggtctgga tagcacgaaa agtcatatca tctagattgc caatcggcgt tgccactaga
     2341 tacagcttgc catagggaga ctgcccctta aaactttttt gaatttgcat gcttactccc
     2401 tgtataacaa ctcatcacag aacatacatt cttcgtcctg ctctcgacgt tgtccataaa
     2461 aatcattaca tacgtgaaat ccatcacggt aaatacgacg gacactttcg cgaacatgct
     2521 tggccttgac gggagcgtct gcttccacct cacccaagcg ttctcgcaac ttactatttt
     2581 ccaagcgaag agctgtattt tcttctacca agctcttgag atttttcttg atggcttcca
     2641 catcggctaa agttaccaat aattgttggg aaaaatcatc cagcgcgtca aataattctt
     2701 ttttgtccat aaaacagccc tttcctttct ttatcattca tttttgagtt tatatttctt
     2761 tcaagaccag atattccatg gcattttgaa agctgacatt agcttgccac atttttctag
     2821 cttctagtaa atcttgtaga atcactctta ctcttacctg caagaggtcc tgcccacaga
     2881 gaacttcaag aatccgtaaa acctgatcct gtttttcctt atcatctgcc aagttggcta
     2941 atttggcaac ctgtagataa ctttcttttt tcttagctac taaccaagtc agcaggcgtt
     3001 cactttcatc gaccaaggtc caaaaacttg cctgattagc caacttttct gcttcagctc
     3061 gcgattgact aaacttagct aaaagagtcg cttttttctt aacaagtccc atttgttcta
     3121 agagtaagat aagtttttct tcttgctttt taaagtggaa gatctgagtc cgacttcgga
     3181 ttgtcggtaa catcttttcc tcatcgctag tcaagaagaa aatataaact tcactctggg
     3241 gttcttcgat gaccttgagc agagaattgg ctgcgttggg atgcatttta tccgcttgct
     3301 cgatgataaa gacctgttgc tggctttcaa tccctgcttg agaaaactgt cccaccaatt
     3361 cccgaatacg ttctgtcttg atgacctgat tgactggctt aatcaaggtg acatctggaa
     3421 actcttcctg ttcaatcagc ttgcaacttc ggcatttctc acatggtaag acgccaactt
     3481 tatccgtaca aaagaggctc ttagctaaaa attgcgccat ttccaagctt ccaaagaaac
     3541 ctgaaaagag ataggcgtga ttgagctggt cttgttctaa gatacggaca aaacggtcaa
     3601 actgagctgg ttgccaagcc tttagttgat cttgtttcat ttggccaagc ccattccgtc
     3661 aaacaagaca gccttggtag tttccacaac ttgctccaaa gggagactag catcaatctt
     3721 gacaatgcga tttccctctt tatccagaag agaaaggtag ccttgacgaa cttttttatg
     3781 caagtccaac ccttccaaat ccaaacgatt aacctcgcgg tcactattag cagcaatacg
     3841 agccagccct tcttccacct cgatgtcaaa atagagtgtc aaatcgggtt tgaggccatc
     3901 tgtcgcaaac tgattgagcc agtcaatggc ttcaatatct aagccacgac caaatccctg
     3961 ataggcaaca gaactatcga taaaacgatc catgatgacc aacttgccag cttcaagggc
     4021 tggaagaact ttttccacca aatgctgtct gcgactggca atatagagaa gtagctctgt
     4081 tttagcatcc atctgagtat gacttggatc caaaatcact tcccgaatct tctccccaat
     4141 caagactccg ccaggttcac gggtcgtcag cacctttact cctttttcct ctaaaattgg
     4201 tagcagagcc tctaaaacac tggtcttgcc tgctccctct ggtccctcaa gagagactaa
     4261 aaatcctttt gacatgtcta actcatttct tttttactac ttctattcta tcaaaaaaat
     4321 aggggtttgt gacaatcttt ttgtcttctc atttcatact caatgaaaat caaagagcaa
     4381 actaggaagc tagccgcagg ctgtacttga gtacggcaag gtgaagctga cgcagtttga
     4441 atttgatttt cgaagagtat cagccaccat aaaagaggca gataaaacta cctcttattt
     4501 acctagttct tgtgttcgtt tataggcttg atgaactgcc tccatgactg tgcctcgaaa
     4561 agcatgcgct tctaggcttg ctacgccagc aatagtcgaa ccgcctggac tacaaacttg
     4621 atctttcaaa actccaggat gttgctggct ttctaggacc aattgcccag ctcctaccac
     4681 agtttgggct gccattttca aggctgtttc tcgtggtaat cccgtctgaa cacctgcatc
     4741 tgccaaggcc tcaataaaga gatagacaaa ggctggtcca caacctgcaa gacctgtcgc
     4801 tgcattgatt aagctttctc ctaattcaac caagagacca gccttggcta aaagctgaca
     4861 aaagatctca ctgtcctcag ccctgcaatt aggagacaag gcataactaa tcactccttg
     4921 cccgatagaa gcaggggtat taggcatcat acgaataatt cggtgttggc ttgggataag
     4981 acttgctagt ttttctaagg tcaatccagc tgccatcgaa atcaaaagaa gactttctct
     5041 tttttcaagg atggtctggt attgagaaag cagttcagaa aactgagcag gcttaacacc
     5101 tagaaaaatc acatctgctt cttcgaatat ttcttcattg ttagaagtct gaccaccgaa
     5161 gttagcgatg aaagcatcca ccttgacttg actacgattg gcaaggagaa tctcatctga
     5221 cggtctagcc tgcaagacag acttggttaa actagcaccc atattcccca aaccgataaa
     5281 tccaatcttc atctcttact cccttatctg tccatcacca gtgaccacat acttgtagct
     5341 agtcaattcc ttcaagccca taggaccacg cgcgtgcaat ttctgagtag aaatccccat
     5401 ttcacaacca agaccaaatt gtcctccatc tgtgaaacga gttgaggcat taacatacac
     5461 cgctgcagag tccacttgat ctgtaaagta tgctgcagct tcagcatttt ccgtcacaat
     5521 ggcatccgaa tgatgggtac tgtgggattc aatatgcgca accgcttctt ctaaactgct
     5581 cacaacctta acagctagaa tatagtctaa aaactcggta tcaaagtctt gtgcttgagc
     5641 agcttgacct gaaacaaact ggcttgcttt gctatctagg cggaattgaa ttggttccaa
     5701 cccagcttct tttcgatctg caaccaacac ttgctccaag cgaggaagga agcttactgc
     5761 tttgttttca tgaaccagca gaacctccat ggcattacaa acagaaggac gactggtttt
     5821 agcattgttg atgatagaca gcgccttgtc ttcgtctgca tccttatcca catagacatg
     5881 gacaatccca gttcctgtct cgataacagg tacaatcgca ttctcaacca ctgcattgat
     5941 caagccagct cctccacgag gaatgagaag gtctagatag cccttggcct tcatcatagc
     6001 ataactactt tcacggctag tatcctccac cagttgaatc acatttggat gaatagtagt
     6061 cgtctccaag cccttcttca aggctgtgac aatggcatgg gttgtttgat aggcatcctt
     6121 accactacga agaacaaccg catttccact cttaagagtc aaagcagccg catcagacgt
     6181 cacatttgga cggctttcat agataatacc gatgacaccc atagctacac gtttttttgt
     6241 gataaccaaa ccattttcaa gctgacttgt ttctaaaact tcaccgattg gatctggtaa
     6301 ggcaaccact tcacgaattc ctcttgccat cgcttctata cgatctgcat ccaaataaag
     6361 acgatccaac atcacatctg agattttccc cttagccgct gccatatcga gggcattagc
     6421 cgctaaaatt tcctcagtag cagccactaa gtgatcagcc atggctagca aggcttggtt
     6481 tttcacttct tcactagctg tgttaatcga ttttttaaca gcctgtacct gttcaaattg
     6541 ttcttgtcta ctcaccatag tttacctcta aaattctgta aaaagtagtt ggatttcagg
     6601 agtaatggaa atccagtcgt cacggtaaat caagacaccc ttggcttttt gaaaacgcaa
     6661 catatcctcc aaagcagatg ctccaaattg cacgcgtcct tttccaagtg attttccact
     6721 ttccttatca aatactgtca cgatatcacc gtaagaaaag actccttctg cttcaacgat
     6781 accagataag agaagactct ttccatgttg agagagagct tccgcagccc ctttatcaac
     6841 ccaaatagaa ccttgactct gagcatagaa ggcaagccat tgtttctggg tacgaagccc
     6901 cttctcttga gcaacaaagt aagaaccatc ctcggtctcc tctgccgcct caaccatgga
     6961 atctgatttc aaggatgagc agatataaac aggaactcct gattccgtcg cgatagttgc
     7021 agccttgatt ttggttaaca tacccccagt tccgtttgac gaaccagctc caccagccat
     7081 atcaataatc tcacgattga tggtctcgat tctctccaag cgtttggctc ttggatctga
     7141 attaggattt ccagtataga gaccgtccac atctgtcaag aaaactaaaa ggtctgcttg
     7201 gaccatcgcc gctacttgag cacttagagt gtcattgtcc ccaaccttga gctcatcaat
     7261 aacgacacta tcattctcat tgatgatagg aattgcccca cggttgagca aaaccgacaa
     7321 agcctgatgg gcatttttat aacgacgctt atccacaaag tcatcttggg tcagcaagat
     7381 ttgtgcagaa acgatttgac gcaagagaag attggtcgta tattcttcca acaaaagtcc
     7441 ctgccctacc gctgctgaag cctgtttatc agcaatttta gtcggacgct ttttaaatcc
     7501 taaggctcca aaaccagccg caatggcacc tgaagacacc aaaatcaact catgaccagc
     7561 ctcgtgcagc atagccaact gctgggtaat atcctttacc ttactacgtg ataaacttcc
     7621 atcctcattt gtcagagaag aagtgcccac cttaaagaca atccgtttgt atttcatagt
     7681 ctcactccga ttattcatat ttatccatta taacatgaat aacaggaaat agaaaagagt
     7741 tgataggaaa aagaaggccc taaaaccttc ttttctacta ctattctgat tccgatttgt
     7801 ttacactcgt ttcagagctt tgtgaagttg aggatgtcaa atcttgacta gttgaagaat
     7861 ttgtaacact ttcatgttga ctcgtttctt tattttcaag atcctttttc actacttctt
     7921 tggattcttt tatttctgaa tgacttgtag ttttaattgt agcagatttc tcgatcggaa
     7981 catccactaa ccaggcacca cttgaatcca cagtatagcc ttctggtgtc ttaccattca
     8041 caagtaattg accattttct ttcaagaagt accatttatc cttgtcttta atccaaccta
     8101 tagctcgtga accacctgtc ttgtagaaat accaatcatt tgccttttta agccagcctt
     8161 gcttcatagc tcctgattct tctagatagt aatgatgtcc agcaacttct atctcacctg
     8221 tcttcatgat accagtagaa tccatatagt accaggcttc tttatctttt acccagcccg
     8281 ttttcatttc ccctgatgga gcaaagtaat accattgccc cttatattga agccaacctg
     8341 tcttcataga gccatcaaca tccaaataat accactgctc tttatcttga acccaaccaa
     8401 tttccatctg attttctttg ttaaaataat accagattcc atcaattttc ttccaatttt
     8461 tagcagaagc accagagtct gtcaaataga accaatgatt gttccatttt ttccattgat
     8521 tctgtaacaa gatacccgtt tggttaaagt aataccattc accttcgatt tcattccaac
     8581 cgacagcata ctctcctgta gaatcaggcg cttgatacca ccagttccca tatgcactct
     8641 tatgccaacc agcttgaaaa cttggaatcg gcttgtagga tgttgaaata ttgacaaaac
     8701 cgtcttttcg aatatcaaaa actgttgcat catagtcttt gctggctgcg ttgattctct
     8761 caattcctcg ttctttgagc caattaacat actcactatc aacaccattt ttccaaggta
     8821 gactatccga agtttgaaca atcaaactcg gactcaaatt tttaatgaaa tccttggtat
     8881 ttgatttgtt ggtatcatgg tgatgattaa acttcatcaa atcaactttt ccaatgagag
     8941 gaccatactt gtcttctgct ccatgaacat tatctaaatc gcccccaagg taaattttct
     9001 tgccattgac tttcaccacg ctaatcaagg aattggaatt gtcatcccaa attttcttta
     9061 attcacccga tgaatcagtt tcattttcat aattatagag ctgaatatcc atgtccccaa
     9121 actgaaaatg agcatcccct tgtgtgatat tttgaataac tgaaacacct ttttctgcag
     9181 cagtctgtaa aaccttatca tagccataca gattatccca tagacgttca gaattagtaa
     9241 tacgactatc actatatttc ttaagataga ctcggtcaac tggataggta gacagtaatt
     9301 catcaacatt tccaatatga tcactgtggg tatgggtcac caaaataaaa tcaagttttt
     9361 ggacacccaa ttccttcaaa cgacgaaaga cacggtctgt tagaacatgc ttataagacg
     9421 tttcaattcc ttctctccat ggataacgag aatcacttcc atctgggaaa tcataatctt
     9481 ctcctgtatc caccatggca aaatgtccat tgctttcaag aataatcgca tcactgccac
     9541 cttcttgaac attgataaag tggattttat ttcctgaact ttcttgagcc tgaacattcc
     9601 cataccatga caaacctaaa aaagcgccta caagtgctaa actagttaat ttctttttca
     9661 ttcttacttt ctcaatctct ccaaggtttc cttaaaaatc tctgggatat ctgctttaaa
     9721 ttccaaggtc ttacctgttc tcggatgagt aaaacctaaa gtcttggcat gaagaaattg
     9781 tccatgtcct ttcaaagtct tgcgaggacc atagacctca tcaccagcga ctggatggcc
     9841 gatataagcc atgtggacac ggatttgatg agtgcgccct gtctccagtt gcaactctac
     9901 taagctataa tcgccaaagc gttccaagac gtgaaaacgc gtcactgcag gcttcccttt
     9961 agcagttaca gcctgtttct tacggtcttt ttcactccgg ccaatcggcg cttcaattac
    10021 accacgatca ttaggcagat ttccatgaac aatcgcccaa tatttgcgga gagacttttt
    10081 atctttgagt tcttgggcaa gtactagatg cgcatcatcg tttttagcaa tcatgagaag
    10141 acctgacgta tccttatcaa tacggtgaac aatccctgga cgcagaaccc cattgatacc
    10201 cgacaagtcc ttaatatgat acatgagggc atttactagg gttccactgg tatgaccagc
    10261 actcgggtgc acaaccattc cctgaggttt gttaacgaca gccacatcct catcttggta
    10321 gactatttct agcggaagat cctcagccac atactctaat acctctggtt ctggcacatg
    10381 gtaagtgacg acatcaccct cttggactgt gtatttagct ttcttgactt gaccattgac
    10441 caagacctgg cctgatttaa tttgttcatt cgcgagacta cgtgataatt ctgacaaatc
    10501 tgacaaagcc ttatccaaac gcagaccacc agtttcaatt ttaatttcca tttatttcct
    10561 cttttagcat tgcaatcaat aaaataatca ctccaaccgt cagatagcta tctgccacat
    10621 tgaaaattgc aaagttgata aagtcaaggt ggaacatatc cacaacaaag ccctgactga
    10681 ccctgtcaat aaagtttcca agaccacccg cgattattag agtcaaaccc aagaacatcc
    10741 agaatgagtc ctccatgtgt ttatgtaaat accaaatggc acctatcacg acaaccagag
    10801 taatgacagc gaataacagc tgctgatctt gtaagataga aaaggctgca cctcgatttt
    10861 gcaggtaggt caagctaacg aaattgggaa tccaggagcg cacttcaccc agtggaatct
    10921 gctggacgat ataggatttg accaactgat ccagcccaat taaaagcagt acaatgactg
    10981 ccactattgc tctttttttc atgatttcct cttttgatca aaatattctt gcatgacttc
    11041 tacgaagaga gtcccagctt gactaagctc cacttcttca cgtttaacat agaccatgcg
    11101 gttatctagg ttatccttga gacgaataac tgtaatgcca ttaacactgt cactatctaa
    11161 aaatccagaa cctgtcgcat aggcgtccgt ccgctccaaa ataccattca aggtggcacg
    11221 gtctgtcaca ttaaacatct gtgagctagc gctggtatcg acaaagttct ctgaataata
    11281 aaggtactcg tctttctctt gagtgaaacg aaccgttggt aaatccgcta aatcctccat
    11341 gactaattcc tctttctggg ctaaaggatg accctcacag agataaatat gggtatggaa
    11401 aggaatcaat tcgatgacct ccagacctaa cttttcaacc cgttgcataa tccccttttt
    11461 attttgattg ttgaggtaga taatcccaat ctcactatgc ccttgcgcca cttcatctaa
    11521 tatttgaaca gtagttgatt caaaaatacg gaagttctta tagtcaggat agcgctctga
    11581 aaaggccgta atagttggtg gtaagaagtc atagtgctgg ctagcaacgg aaaattcatc
    11641 tttttcttct tcaggattgg catactgatt ttgaaaaata tcaaatcctt taaccaattc
    11701 ttgcgctttt tcataaaatt ccatcccacg acgggtcaag aaagtccctg agctggtccg
    11761 acggaaaatc ttaaagccca actctttttc caaatcacga acagaaatag acagactcgg
    11821 ctgactaaca tacatctttt cagcagcttc acgaaaagta ccactattgg caatagccac
    11881 aacatagcgt aattgttgaa tgttcatctt ctacccccaa cttctttatc ttttcattat
    11941 accatatttt agaagttttc caaaaaggaa aaaagaacat cctattcttc ttaactatct
    12001 tcactatctg cctttctcac gccaatctta ttttcaaaat caattcaaaa aaataagtgg
    12061 ctacacacca cttcagtatc ggaaagaaaa acgttgacta tttgtgaaaa aagaaaatgc
    12121 cggaaaattc cgacattttt ttagtaagct aacttcctga aaataggagt aaccaaacat
    12181 cccagaaggc agtgatattg atgagaatat gaactagtat tggatagtag agatttttag
    12241 tcatgcgata caatagagct aaaatcagac ctccactagc ataaatgaaa aaagcaagag
    12301 gagttaaagc aaaattgata tgaatataac cgaaaataat agcagaaagc aaaacatctc
    12361 cgtaccaagg tgagtttttg aaaaaggttg tcataagcac acctcgataa atcaattcct
    12421 cagcaatagg ggcgatgaag caaacgatga gcaagaaata agggaactcc tgtctcccca
    12481 tcatttctac cgtttcattc aaagaaatct gatttgaaga cagggatatg aaatacgaaa
    12541 agaggaagtc agacatatat gaaatgatgt agcccagtaa aaggtagatg aagtacctca
    12601 gctgccactt gaaatgaaaa attttctttc ctgcaaaaac cagtagatag atgaccgcta
    12661 agaaaagaac tccgctctcc atcaaaagca gaatctgaaa aaattcacga cttgctggta
    12721 gatagggctt tgcgaggtga ttgaaaactc tccaaaacca agttgatttg taaaaaatta
    12781 aggacaatgc tagtaaaatt tgaatagccc gttttttcat attaaattct ctgctttctc
    12841 cacttatttc ttcatattac taataaattt tacttaaaat ctcgcagcac ttcctttgca
    12901 aagatgattg cctcctccaa tatatcctaa atcataggtg cctctgggac aaaatccatg
    12961 aaccggcaga gttaatactg gttctatttc ccaatcgtac ctaccattag gatttttacc
    13021 atatgaatct gctccacctt gtatcagctc taattcttca tttgttagat ttatattttt
    13081 tgtcattaaa atcatgatat atttcctcca ttattcttca gattagttga gtaatctgat
    13141 actcatacct acttacaaaa aaactattat attaagttgg ttttttaatt tgtctagttg
    13201 caacattgac aaacatagta tagcatatct ttgcgaaata tcctcttcaa atcatgaatt
    13261 gtcatcaaaa catcttaaac tataaaatca attagtctca agctttctat caatttcttc
    13321 tccaaaatat gctataataa tagcaaaaga taaagaagga agacctatga ttaaactact
    13381 agccttggat atggacggca ccctcctcaa tgaagccaag gaaatcccac aagctcacat
    13441 tactgctatt cacaaagcca ttgaaaaagg tgtcaaactg gttctctgta cgggtcgccc
    13501 ccttttcggt gtcctcccct actacaaaaa actgggactc gacctccaga atgagtatgt
    13561 gattgttaac aacggttgtt caactcacca gactagcgac tggggcttgg ttgactggca
    13621 agaacttagt ccagctgaca tcgaatacct ctatgacctt gctgaaaaga gtgatgttca
    13681 gttgacactt tttgacgagt cacattattt tgttctcggt ggaaagccca atcaagttat
    13741 tgaaaatgat gctaaactag tattttcaga cctgactgaa atttctcttg aggaagcgac
    13801 tagtggaaag ttccggatgt tccaaggtat gtttttagga acaaaagaac aaacagacga
    13861 ttttgagcag cgttttgctg aagagctttg ccaacgattc agtggagttc gttcgcagcc
    13921 tgtcatttat gaagcaatgc cacttggaac gacaaaggct actgctcttt cacgactagc
    13981 tgagattttg aagattgatt cctcagagat tatggccatg ggcgatgcta ataacgatat
    14041 cgaaatgctc cagtttgcag ggcttgggat tgcaatggga aatgccagcg attatgtcaa
    14101 atctcttgcg gatgccgtta cctcaagcaa cgaagaagac ggcgttgcgc gtgctattga
    14161 gaaatatatt ctataaaaaa gaaaagcaaa tagacagaag ttactgctat ttgctttttt
    14221 gctaatattt taaaatacgg actaatcaat agagaagaat agcgaatcat aaaaatcgat
    14281 ttactagatg ccatagtatc ttatagttgc taataagaag ttagtctagc agaatgaatc
    14341 tctcatttct cccacactaa tctgtaattt gtctatacat ttctggtctt ctatctcgaa
    14401 acaagcccca gtttaggcgt tcacttgctc ccttgtctag gttataagta gctaacagaa
    14461 cagcttcttc ttgtctttca gctcgttcta gaatagctcc tgtttcatcc gtcataaagg
    14521 aggaaccgta gaagtcaaga ctggaactct gtccgccatt ttcctcacta ggagtaacct
    14581 cctctaaacc ataacgattg gctgcgatga ctggaacaat attcgctgct gcgtgccctt
    14641 gcatagtacg ttgccagtga ccacaactat ctgtatccaa aattggctct gaaccgatag
    14701 ctgtaggata aaagagcaat tcagcaccat tcaatgcaag acagcgcgct gtttcaggga
    14761 accattgatc ccaacagata ccgataccaa tcttagcata gcgagtattc cagaccttga
    14821 aaccagtgtt accaggcgtg aaatagaatt tttcttgata ataatggtca tctggtatat
    14881 gggtctttcg ataaacgccc agcacttccc catctgcatc aatgacggca atagagttat
    14941 acaagacatt accatctttt tcatagaaac tgattggtaa aacaacttgt agttccttag
    15001 caagcaactt aaaatgctga atggcagtat tttccgctac agattgggca tactggtagt
    15061 agtcatactg acgttcctga cagaaatagg gatgttcaaa caactcgggc aagagaataa
    15121 tttgggctcc ttgctcagca gcctgacgta ctaaacgctc tgcggtttgg atatttgttg
    15181 ccacatcctt agcgcattgc atctgaatgg ttgcaactct tacatttctc atctttttct
    15241 cctattctgg aatttgttgg gtgatacagt ggatattgcc accacctaag agaatatctc
    15301 tggctggtat tccgacaact ttacggtctg ggaaacactt gctgaggata tctaaggcca
    15361 cttggtcgtt tacatcctca aactgtggaa ccaagacagc cttgttggcg atataaaagt
    15421 ttacgtagga agctgctagt cgttcacctg cgtatcgctc ttcttctcct tcttcataga
    15481 tgtagcctgg caaatcttct tctgtcacaa cttgtcgaac tgcagggata ggcaatttat
    15541 gaatggtgaa gtgacaacct tttgcatctg tttcctgttc taagagttcg agatctgctt
    15601 ttgacatggc atactgggga tcattttcgt catctgtcca agccaaaaca acctcagcag
    15661 gaccaacaaa ggcaacaaca ttatcgacgt gttcattggt ttcatcctga taaataccat
    15721 aaggaagcca aataactttt tcagcaccaa gactttctaa taatgtgttt tcaatctcct
    15781 ctttagtcaa gttaggattg cgaccaggac taagcaagca actttcagtt acgagaatag
    15841 ttccttgacc atcgctatgg attgcgcctc cttccagtac aaaaggttta gcatcataga
    15901 caggcctttc caaggcctca gcaaaacgac tggctacttg gtcatcctct tcataatctt
    15961 gataaagacc atcataggtg cctccccaag cattaaaggc ccaatccacg gctaatttct
    16021 tacctttatc attgacgaga atggttgggc cagtatcacg cgcccaggca tcattggtgg
    16081 gaatgtctaa ataaacaacc ttgtctccaa gataggattg ggcttcagat agataggcct
    16141 gctccaccaa aagatagact ctttcccctt ctgctatggt ctcgatgatc tgagtaaatg
    16201 ctcttttagc agcctttcct tgaaaaggcc atgatcctgg tcgagtcggc catatcatga
    16261 gggtaccatg atggggttcg tactctgctg gcatgtgata gcctaatttt tttggactgt
    16321 ccatcatgat aatctccctt taaagtcttg atagccaaaa gctttgagta agctacagtc
    16381 tccctgttcg tccatgagat agagacttgg caatccaata ccattaaagg tattattttt
    16441 gacaaaagaa taaatggcca tgtcttgaaa ataaagtctg tctccgattt ggactggatt
    16501 ttcaaaacta taatcaccaa tcacatcgcc agtcagacag gtattagaag aaagtctgta
    16561 ggtatgggct ttttcctgtg actcaaagcc atttctcaaa ggtggacgat agggcatctc
    16621 aagtacatca ggcatatggc aggtcgcaga ggcgtctaaa accaagattt ccataccgtt
    16681 ttctacaata tctaatacct cagttgctaa ataacccgca ttaagcgcaa tggcttcacc
    16741 aggctcgata tagatttcaa gattgtaagt ttttcggata cgcttgattt ctgaaatcag
    16801 caaatccaca tcgtaacctt ctcttgtaat atgatgacca ccacccatat tgagccattt
    16861 tacctcatgt aagtagggac caaactgttc ttctactgct ttcaaagttg tttgtaaatc
    16921 atctgctccc tgctcgcaaa gggtatgaaa atgaagtccg tcaaccaaat ctagcaaatc
    16981 gctcggaatc ttgtctatag taactccaaa gcgagaacca ggtgcacaag ggtcatagag
    17041 cgcgtgatct ccttgagttg aacactgagg gttgaggcgc aaaccaacac tgacaccagc
    17101 ctctcgacaa cgagccccat gcttacgcaa ctgtctctct gagttaaaga cgatatggtc
    17161 tgttatccca agcaattcct ccatgtcctc atccttgaaa gctggtgcaa aaacatggac
    17221 ttcaccagga aattcttccc ttgccaattt ggcctcatag agtccactag ctgtcgtacc
    17281 tgatagatac tggctaatca agggataagt tttgtagagg gaatatgcct tctgggcaag
    17341 caagaccttg caaccggcct cttcttgtac atattgtaga atgcggcaat tagcttctaa
    17401 cttggccaag tcaataacat aggctggtgt tggtacttgt tctaacttca ttagtccaac
    17461 atttgtggat tttcaaccac aacccatggc aaaccatact cattcaaagc ttccatgaat
    17521 ggatctggat ctaactcctc aaggttatac actccagctt gtttccaagt tccgttcatg
    17581 actaattttg tcccaatcat ggctggaacg cctgtcgtgt atgaaattgc ttgtgacccg
    17641 acttctgcat agcactcttg atggtcgcaa acattgtaga tgtagatagt cttttcaacg
    17701 ccatctttga cacctgtaaa gatacatcca atattggttt tacctacagt acgtggacca
    17761 aggctagcag gatctggaag caaggctttc aaaaattgaa ttggaacaat ttcttggccg
    17821 ttaaagttaa tggtatccgt acgaaggagt ccaacatttt caagacattt catgtgcgtc
    17881 aagtaagatt gaccaaaagt cataaagaaa cgaatgcgtt tgacacctgg aatgttcttg
    17941 gccaatgatt cgatttcttc atggtgaagg agatacatat ctttttgtcc aacttgaggg
    18001 aaatcatact cacgcttgat agacatagct tcgacttcga cccatttccc atcttcccag
    18061 taagaacctg gcgcagaaac ctcacggaga ttaatttctg gattaaagtt ggttgcaaat
    18121 ggataaccgt ggtcaccgcc attacagtct aaaatgtcga tataatggat ttcatcaaaa
    18181 tagtgtttga gggcataagc tgaaaagaca ctagttacac ctgggtcaaa accagaacca
    18241 agaagagcag tcaagcctgc ttctttgaat ttctcttgat aagcccactg ccatgagtag
    18301 tcaaagtagg ctgtaaaacc aagttcctta caacgttttt cgtagatagc acgccactca
    18361 gggtcttctg tgtcttctgc ttcgtagttg gctgtatcga tatagtgaac acctgttgcc
    18421 aaacaagcat ccataatggt taaatcttga taaggcagag ctacattcaa aacagcttct
    18481 ggtttgtagc tttcaatcag agcaatcact tcttcaacct tgtcagcatc aagagcagct
    18541 gtctcaatct ttgtacttgt tttgccttcc agtttagctt tcaagtcatc gcattttgac
    18601 ttggtacggc tagcaatcat aatctctgta aatgtttcgc tatcttgaca aatctttgaa
    18661 atagcaactt gggcaacgcc cccacaacca ataactagta aacgactcat ttttttcctt
    18721 cctcttcttc taaaatgtcc tcaacatact tgggcaacat aaaggctccc acgtgtaagt
    18781 ttgcagtgta gtattctgtg aaaagctggc gttttttcca gccttccttg tcaaaatctt
    18841 tgacagggtg gtattttttc gatgcaaatc caaacaacca atagccagct gggctagttg
    18901 gaatatgggc ctgataaacc cgactgattg gaaaggcttg attgaccttg cggtgcatgc
    18961 ttcggcaggc cgactcatcc tcgtcaaaga acggactccc atgctggtaa atcatgatgc
    19021 cgtcttcctt cagagctcga taactattgc cgtagaattc cttggtaaag agtccttccg
    19081 tatggccaaa tggatctgtc gcatcgttga tgataatatc atagtcatat tcgcagtttc
    19141 gcaaaaagcg tagcccattt tggtagtaaa tggtaacacg aggatcatct aggcctgcag
    19201 caaagtctgg gaaatactca cgacagacct cgaccaacat ctcatccggt tccacgatat
    19261 cgatttgttc cagttcagga tagagtgtta atacttgggc aacaccgccg tcaccacccc
    19321 caataaccaa tactttcttt ggatttgggt ggacagccat gggaacgtga acggtcattt
    19381 cattgtagac gaaatcatcc gcatctgaga acaagacatg gccatttaaa atcagtattt
    19441 tcccaaaagc tggcgtatcc aagacttcga tatcctgcca ttcacttttt ccagcgtaaa
    19501 gttgcttggc tgttctcaga gacaatttga catctggagt atgaacttca gaaaaccata
    19561 aatccatcta tttctcctta tattatattt agcgcagtta gctactgcca aagcccaagt
    19621 ggtatacttg gaataagcca ctgtggatta gttcatttcc tccaatcgct tgacgatttc
    19681 cgaaagggtc taaccacagc tttttgtttc aattggtaat gagtttgata acgcatagac
    19741 gttttatctc gtctaaggta acaaggcaaa aagttcgtgg ataaccaagt agacttgaaa
    19801 tactatatct ggaggtactc ccatgcttta tgtgggcatt gatgtcgcta aaaataaaca
    19861 cgatgttaca gccttgaatg ttcgaggaaa actgttctta aaccactcac tttttcaaat
    19921 aataaagctg gttttgaact cttagatctg tctcttcgac aactcaacca agactgtctc
    19981 atcgctcttg aaaataccgg acattatgcc tttaatctac tgaacttcct gcatgaacaa
    20041 ggatataaag tttacaccta cactcctttg ctcatcaagg aatttgccaa atcattatca
    20101 cttcgcaaga ctaaaacgga taagaaagac gctcatggca tcgctcttaa acttctttct
    20161 gaccccaatc gtgaacaatt tcaacacgat aatcggcaag tagaactaaa aatactgact
    20221 agacatattc atcgtctcaa gaaaaaacag tctgattgga aagtacaata cactcgttgt
    20281 cttgatatca tctttcctga gttggataaa atcgttggaa agcattcaga atatacctac
    20341 caactcttga cacgctaccc taatcctcag aaaaggattg aggcaggatt tgataagctg
    20401 atagaaatta agcgattgac cgcttctaat tcaagggctt tttgccgtgc tctaaaatca
    20461 tcgccaaatc atcaaattga aataagaaat agtttagata aactattgac ttttcttata
    20521 gtttgtcttt ctcttaataa cgttgatatg attgacctct ggatcttccg tcccttggag
    20581 ggagcaacca cgttccttgg cgaattggat atagtcgaca atttctcgtg taatgcgttc
    20641 accaggagcc aagataggaa tacctggagg gtaacacata acaaattctc cacagacctg
    20701 tccaacagaa tcatccaaag ttaaactttt tctttctgaa tagaaggctt cttgcggaga
    20761 cagcactaac tcgggctgaa tatattctcc tgctatcaaa tcttttccat ctcttgaata
    20821 gagtctctta atatcagcca gagcaccaac caagcgctcg atgtcttgga tgcggtcgcc
    20881 gatggaaata taggccaaga tattgccgat atcaccaaac tcgatctgaa tgtcgtattc
    20941 gtctcgcaag aggtcataaa cctcgatacc tgttaagcca ataccctgag tgtaaactga
    21001 caacttagtt acgtcaaaat cgcaaaccga aacaccgtct attaactctt ttgagtaggc
    21061 atagtagcca ccgatagcat tgatttcatg acgagcgtac tcggatagct caatgacttc
    21121 ctcaaacgac tctttaccac gaagggccaa gttgcgacgt gaaatatcca aactagccat
    21181 caataagtaa gaggcagatg tagactgggt caggtttata atctgacgaa cgtactcggg
    21241 attcatctgc tccccgatta aaagaagcga actttgtgtc aaactcccac cagacttatg
    21301 catggaaact gctgccatat cagctcctgc atccatagca gaaattggaa gtttaccagt
    21361 gaaatgcaaa tgcgctccat gggcttcatc tactaaaacc atcatgccag cttcatgagc
    21421 catttctgtc aaccccttta ggtctgaaca gatgccgtag taagtaggat tgttgattag
    21481 gatagcctta gcatctggat ggtcctttat ggcctgtgct actcggtcat tttcaagacc
    21541 taaagcgata ccaatcttag gatctacact catctcgata tagatgggaa tggcaccaca
    21601 tagaaccaac gcattgatag cagatttatg gacatttcgt ggcagaataa tcttatctcc
    21661 tgccttgcag gttgccagaa tcatagtctg caccgatgaa gttgttccac caatcattag
    21721 aaaggcatgg ctagctccaa aagcatctgc agccagctcc tctgcatcac gaataatcga
    21781 aataggatgg cctaaattat ccaagggttt catcgaattg acatcaatgc ctacacattt
    21841 ttctcctaag agttcgacaa gttctggatt tccccgtcca cgcttgtgac ctggaacatc
    21901 aaagggaaca atccttttct tgcgtaactt caccaaggcc tcataaattg gggcttggtt
    21961 ttgatctaac tctttcaaaa catactcctt tcaatatttt taggacctta tgaaaactaa
    22021 ggaactaaag gttgactcat gaaaaaagag caggttttca cctgctctgc aatcttctga
    22081 cgtgtttatt ttggtttctg ttgagtatgt ctgttcccga tgtttcctaa ctctctagta
    22141 gcaaatatta cgtactttat tgatcgtttc acaagatgac gtgtgctttc accacactaa
    22201 aaatttatga attaggacaa gtgtcctaac atcaacttat aaaagtaggc ttttaaccct
    22261 atcaataatg tggcttttca accacgcttc ggcattcaac cctgcctgtc cgtaggcatt
    22321 ttttactcgg gtttatattt gctagaaaac atcatctcat tttctaagct ttattactat
    22381 atcatgtttt taagaacttg taaagtattt tttgataaaa aacaaaaata taatagattg
    22441 aaactagaat agtacacctc tgcttctaaa acattgttag aaatagattt tactgtcctg
    22501 atcgatttgt tctgttcttg tttcatttta ctatatgttc gtaaatgaaa gttctataat
    22561 gaagttagcc acccagccct cctaaaaatt agatggttca actagctgat agctcttgta
    22621 ggcataagaa aacacctctg tgttatactt gttgttcaac cacaaacaca agaaaggcac
    22681 agaaatgcaa gacaattata ctacaaaagg taaacatttg acaatcgata gccgtcgctt
    22741 aatcgaaaga tggaaaaaag aaggaaaatc aaatagagaa attgcctctc tacttggaaa
    22801 agctcctcaa actatccaca ctaaaatcaa gcgtaggaca gtccgaaaat gtcttggaaa
    22861 agggcgcttc aaagaggttt attctgccga ctatgctcaa cagtcttatg aaaataatcg
    22921 caagcactcg gtcaagagat caagcgtgac caaggaacta aaggaaaaga ttctccacta
    22981 tcataaccaa aaattt
//
LOCUS       DAVAZT010000036        22310 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVAZT010000036 DAVAZT010000000
VERSION     DAVAZT010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22310
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.036"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(160..2118)
                     /gene="ftsH"
                     /locus_tag="VQT45_001327"
     CDS             complement(160..2118)
                     /gene="ftsH"
                     /locus_tag="VQT45_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HET2359647.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEETGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNREIHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(2134..2676)
                     /gene="hpt"
                     /locus_tag="VQT45_001328"
     CDS             complement(2134..2676)
                     /gene="hpt"
                     /locus_tag="VQT45_001328"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HET2359648.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKAREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2680..3957)
                     /gene="tilS"
                     /locus_tag="VQT45_001329"
     CDS             complement(2680..3957)
                     /gene="tilS"
                     /locus_tag="VQT45_001329"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HET2359649.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3954..5222)
                     /locus_tag="VQT45_001330"
     CDS             complement(3954..5222)
                     /locus_tag="VQT45_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HET2359650.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5342..5710)
                     /locus_tag="VQT45_001331"
     CDS             complement(5342..5710)
                     /locus_tag="VQT45_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HET2359651.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5703..5969)
                     /locus_tag="VQT45_001332"
     CDS             complement(5703..5969)
                     /locus_tag="VQT45_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HET2359652.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(6027..9536)
                     /gene="mfd"
                     /locus_tag="VQT45_001333"
     CDS             complement(6027..9536)
                     /gene="mfd"
                     /locus_tag="VQT45_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HET2359653.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYAQHAFIHQLKENG
                     YQKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPIQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKEFKEENSI"
     gene            complement(9537..10106)
                     /locus_tag="VQT45_001334"
     CDS             complement(9537..10106)
                     /locus_tag="VQT45_001334"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HET2359654.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVKYYLQEKNFEKTMQRYNG"
     gene            complement(10177..11292)
                     /gene="ychF"
                     /locus_tag="VQT45_001335"
     CDS             complement(10177..11292)
                     /gene="ychF"
                     /locus_tag="VQT45_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HET2359655.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIIEFRFNV"
     gene            complement(11376..11570)
                     /locus_tag="VQT45_001336"
     CDS             complement(11376..11570)
                     /locus_tag="VQT45_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HET2359656.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11635..12771)
                     /gene="dnaN"
                     /locus_tag="VQT45_001337"
     CDS             complement(11635..12771)
                     /gene="dnaN"
                     /locus_tag="VQT45_001337"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HET2359657.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12930..14291)
                     /gene="dnaA"
                     /locus_tag="VQT45_001338"
     CDS             complement(12930..14291)
                     /gene="dnaA"
                     /locus_tag="VQT45_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HET2359658.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14504..15262)
                     /locus_tag="VQT45_001339"
     CDS             complement(14504..15262)
                     /locus_tag="VQT45_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HET2359659.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15320..16501)
                     /locus_tag="VQT45_001340"
     CDS             complement(15320..16501)
                     /locus_tag="VQT45_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET2359660.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16684..17163
                     /gene="rlmH"
                     /locus_tag="VQT45_001341"
     CDS             16684..17163
                     /gene="rlmH"
                     /locus_tag="VQT45_001341"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HET2359661.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17207..17280
                     /locus_tag="VQT45_001342"
     tRNA            17207..17280
                     /locus_tag="VQT45_001342"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17241..17243,aa:Arg,seq:tct)
     gene            17445..17570
                     /gene="comC"
                     /locus_tag="VQT45_001343"
     CDS             17445..17570
                     /gene="comC"
                     /locus_tag="VQT45_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HET2359662.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            17591..18916
                     /locus_tag="VQT45_001344"
     CDS             17591..18916
                     /locus_tag="VQT45_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2359663.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18913..19665
                     /locus_tag="VQT45_001345"
     CDS             18913..19665
                     /locus_tag="VQT45_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2359664.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19717..19788
                     /locus_tag="VQT45_001346"
     tRNA            19717..19788
                     /locus_tag="VQT45_001346"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19750..19752,aa:Glu,seq:ttc)
     gene            19794..19867
                     /locus_tag="VQT45_001347"
     tRNA            19794..19867
                     /locus_tag="VQT45_001347"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19828..19830,aa:Asn,seq:gtt)
     gene            complement(19908..20450)
                     /locus_tag="VQT45_001348"
     CDS             complement(19908..20450)
                     /locus_tag="VQT45_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HET2359665.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20629..21396
                     /locus_tag="VQT45_001349"
     CDS             20629..21396
                     /locus_tag="VQT45_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HET2359666.1"
                     /translation="MIGISLIPDLYNIIFLSSMWDPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            21481..22161
                     /locus_tag="VQT45_001350"
     CDS             21481..22161
                     /locus_tag="VQT45_001350"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HET2359667.1"
                     /translation="MADGSGKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVS
                     TESKNAEILSNPLNLSKTDNDQVPVNGIAIAPYMISVALFVAAISTNMIFAKLPSGRH
                     PESRWAWLKSRAEINGIIAVLAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMV
                     TTLTTWNSRIGAFFLLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQT
                     ISINKSFS"
BASE COUNT         6899 a         4110 c         3643 g         7658 t
ORIGIN      
        1 acagtccctt ggacttcttc atacaattct ttaatcataa ttttcccctt tctagataca
       61 gtctaacaga ttagaaaaca catttgttcc attttctcca ttctgttccc tttagctcct
      121 aaactgcaca aaaaagagag gctccagcct ctctcagggt tatttttcgt cattcatttt
      181 tgactttact tcatcatagg atagtgcatg agattcctct tctactgctt caggcatctt
      241 tcctgtttcg taaagagctt taatttgtgt actatccaat gtttcgtatt tcaataatgc
      301 ttctgcaatt aacttgtgaa tttcacgatt tgactgaata atttcagcag ctttatttcg
      361 tgcctcattt aataatgaac gaacctcttc atcaatttca taagctgttt gttctgaaat
      421 tgatttttga ggactctgtg caccaaacat agcatggttt ccttcatatt gtactgggcc
      481 aagtttttca ctcataccgt actctgtaac cattgcacgc gccatttgtg tcgcttgttc
      541 aaagtcgttt gaagctcctg tagtttggac attaaagata atttcttcag ctacacgtcc
      601 acccattaag ccagccaatt gctctttcat atcttcttta gatagaagca tttgatcctc
      661 tttaggaagt gcaatcatgt atccgcctgc acggccgcgt ggtacaattg taaccttatg
      721 gacaacgcga gcattcgaca agactagacc aacaatggta tgtcctgcct catggtaagc
      781 aaccaattct cgttcttttt gtgaaactgt cttatctttc ttagaaggtc cagcaataac
      841 tctatcttct gcttcatcaa tatctgaagc atcaattatc gatttattgc gacgagcagc
      901 aactaaagct gcttcattca agacattctc taaatcagca ccaacaaagc ctggagtttg
      961 ttgagccact aatttcaaat caacatcttc tgctaaaggc ttgttcttag cgtgaacttt
     1021 caagattgct tcacgacctt taacatcagg acgaccaacc aatacttttc tatcaaaacg
     1081 tcctggacgc aaaagggcag gatcaagtac atctgaacgg tttgtcgcag cgatgacgat
     1141 aatcccttca tttccctcaa aaccatccat ctcaatcaaa agttggttca aggtttgttc
     1201 acgttcgtca ttacctccgc cgagaccgac tccacgttga cgtccaacag catcaatttc
     1261 atcgataaag atgatagctg gtgctgcttt tttggcatcc tcaaaaagag agcgaacacg
     1321 actagctcca actccgacaa acatttctac aaagtcagaa cctgagatac taaagaatgg
     1381 aacacctgct tctccagcga ctgccttagc aagcaaagtt ttacctgtcc ccggaggtcc
     1441 ctccaaaaga acacctgctg gaatacgggc tccaagtttt gtgaatcgtt ttggatcttt
     1501 taagaactca acaacttcaa ctagttcttg tttttcttcc tcagctccag caacatctga
     1561 aaatcttact ttaatatctt ctttatttgc tgctttagcc ttactacgtc caaaactcat
     1621 tggattacgg ccattgcctc ctcccatatt tcccatcata gagaatagga agaagaatag
     1681 aattccaaat ggcacaatgg atacgagtag attaatccat ataccacttg aactttcatg
     1741 cttaacagtt acttctgctt tatggtcagt agcaagtttt tgcaattctg atacggtagt
     1801 atctgcagga agaatagtgc tggtaaattt ctctacctta gtaacagatg gcgtgaaaaa
     1861 ctgaatacct gtttcttctt tacttgtttt aggattttta tagacaccag aaacttcgat
     1921 aacactacca tttggttggt aagttaattc ttttacatta ccatcggtaa tttcttgtac
     1981 caactcagta tagttgattt gctgacttcc tcctgagtta ttcccagaat agaaatactg
     2041 gaatcctgtc acaaggaaaa agataaataa taaccataga aaaggatttt taattaaacc
     2101 attattttgt tttttcatta aagattattc tttctaattt gaatacactt cctctttcaa
     2161 tactccaata taaggaagat tacgataatt ttctttgtag tctaaaccat aacctactac
     2221 aaactcattt gggatagtaa agcaggtata gtctgcctca atttctacaa cacgtccttc
     2281 tggtttatcc aacaaggttg caattttaac agaagctgct tctcttgctt taaacatatc
     2341 tcgcaaattc ttcaaagttt gacctgtatc aatgatatct tctacaaata gaacatgtct
     2401 tcctttgata tcttgagtca catcttgttt aatattgata acaccactac ttgctgttcc
     2461 accatggtag ctagaaacca tcatgaagtc catttcaata tgtgtatcaa tatgtttgac
     2521 caattcagcc ataaaaggaa tagatccttt taaaatccca actaagattg gattttttcc
     2581 tgcatagtct ttagttaatt gagcacctag ttttttagct gcttctgtaa tttcatcgtg
     2641 tgaaacgagg acttttttaa tatcgttttc taacattttt tacctatcta ttttttctat
     2701 ataaagtaca gtgttcatta tatcattttt cgttttttta ctcaaattat tggtcgcaat
     2761 tcccaaaatt gagacaattt caccaaattg ctcaataata agagcagagt ttctcttttc
     2821 catagggatt ttcaaatcaa taaataaacg tctgagtttt tttctatgcc cattttgaat
     2881 caaaacatct cctgtttttc gatgacgaat gtgtatggat gtttcacgtg aaacaggtat
     2941 ttgttgaatt gattcacctt ctaatggaag tccaaaggaa aataaatatc cttgataagc
     3001 tacctgattt tgatagtgta acacaagttc atcttcctct tcatcagcct gcggactgat
     3061 tttacaaatc tgaaactgtt ggtactcttt tatcaattca tagccatttt taatcggatg
     3121 acgatactgg cttttagatt ttaaaatctg ctgaacttca gcaaactgag cttttgtaag
     3181 attcaaatct ggaaaacgat tcagataagt ttgaagtaaa actctttgtg tagactcaga
     3241 gtaagaaaat aactgctgta aatcttccac attaatattg ttagataatt cagctattgc
     3301 caaatcataa tctaaaattt cattgccaat gcctaagatt gcatccctaa atcgaggatt
     3361 ttctttttcc aattctggta agtaagagtt tcgaatacga tttcgaaaat aatgattctc
     3421 ctgatttgat gtatcttcaa agtgaaaaat tgatggaaag tcttttttct gaaaatgcaa
     3481 gaagggacga atgatttcta tctctccgac tacttgcttc tccttaattc ctgatagata
     3541 gcgcaagcga gttcctcgaa tcaagcgcat caaaatcgtt tccacctgat catcagcatg
     3601 gtgggcagtg actaaagctg tcgcacctgt ctttttcatg acctcttgaa aaaaatcata
     3661 acgaaaattt cgtgcacgcg cttctgaaaa ttctcctgaa aaattgctga tataaatagg
     3721 aagctctgct tcagcagcca acttccttaa ttccttttct tcccaatctg attcaattct
     3781 ctgcttatga ttcacatgag ctagaatcaa ttcaatctct aactcttttt gataagtaga
     3841 caatacctta aatagaaaca tggaatctaa tccaccagaa agagctagaa ccgccttagc
     3901 atgctttttg aaatatccct tcttgagaaa atgatttaaa aaatctggtt ccctcatttt
     3961 agaacctcat aaacatcctt ggctatctta gaaatcgtat cataatcaga attcttagtg
     4021 aaaatagaaa gaataaatgg agaatctgca tagacaacac ccgtatcatg cttaaattca
     4081 tccgcatctc caattttatg agctacttta acagaaacac ctttggcaat tcgctgacta
     4141 tcaaaatctg ttttagtcaa agactctaac acaaatccat tttgattata aatagcttcc
     4201 ataaacttcc cggccatctt agaagaaatc aatttttctt ttggatccca atcatctccc
     4261 ataatggcag acatcttgga tttgaatgtg gcatcagatt ggtttgaaat gtaatatccc
     4321 aatagattat gagctacatt atcagattct tttgatactt tcgtaattaa atcctttaaa
     4381 gaatattctt tattatcttc ttttttagga agactaccac ttccctctgg tttataagaa
     4441 cctggaaaat cattgactgc agatacgtat tttacagtcg tatctaactg ataaagaccc
     4501 tcatttattt tttcttgcgt ataatagaga taagagagtt tcaaaacgct ggctgcatac
     4561 atcttttcat cttgattgat accagcttct tttccagtag tcagttgctt aacataaata
     4621 gagaaagaat ctttctgata tttttcagat aacatttctt gaactttact catccgatta
     4681 tcttcttcag aagttgattc tttagctacc catccagcct gatcaatatg tagaaattct
     4741 cttccttcta caaacatggt cttgtcgatt gatacttgcg aataagctga taaggatgat
     4801 ttcacttctt ttaaatcata aggactattg tacagtttaa agtcagattc taaccatgct
     4861 ttttttattg ttggagttac ctctgattga tcatataaaa atcgtttgtc cgcagctata
     4921 aattgatgat ttgatagctt aaatactgga attccttgtt tatttaagcg ccactcggtt
     4981 atttgaaaac ttgttttggg agtcaatttc ccagattcca ctactaaatc ttcattcgca
     5041 taaacaggaa cctctccata aaccatggga gaacttaatt tttctctaaa ataaatacca
     5101 aagtcagatt gtgaaaggta ataaatttct ttcgaagtat agacgacttc tttttctgtg
     5161 ctaacgactt ttgaaatggt caaaaaactt ggtagcaaca aaataattaa gaatttacgc
     5221 attcttcctt tccttttctt cttgtaaacg caataattga tttttatcag ccaattcttc
     5281 cagcttttca tctgacaaac tcaaaaattg ctctattacg tctaataaat tttccatttt
     5341 atcacctttg aagcaagtca ggaatcgtat aaactttttc cctcgactta gaataatagt
     5401 acttcgctcg tgtatatttg gcagcataat cttcatcttt caacttggta gcaaatgctg
     5461 tctccttatc cttttcatca ctcaaagttt gatactgagt ttgcaagtct gctaattgct
     5521 gacgtctttg gagtaattgc tgataactct gcgctaaatt aaaagttggc aagataaata
     5581 atagcataat caaaatcaat acccctccca taaaacgatt ccgtttttgt cgttctttca
     5641 tcaggtagcg acgacgttgg tattcatttt gaataaaaga attattcaat tgtacaatat
     5701 ttttagacat tttcttctac ccgtgtttca ctgataattt catacattcc tgctgcatct
     5761 tctttttttg tactatcttt catctctagt acttttacaa gcagcaactt attgccaaag
     5821 cgaatttcaa cttggtcatt aactttcaag tccgttgaac ttttggccaa gattccatta
     5881 accttgattc tacctttatc tgctacttcc tttgcgactg tacgacgctt gataattcgc
     5941 gatactttta aatatttatc taatctcatc cttattacct caatttatta ttgtaccatt
     6001 tttatctatt ttatagaaga aaaatatcaa atggaatttt cttccttaaa ctcttttatc
     6061 tctaataaac tttctccaaa aatcagcaga ccttctaaaa tttcataatc tttcttattt
     6121 tggacatcaa atacaagctc cattaatccc ttattctcag cgatgcctgc ttttaagttc
     6181 gttacggata aagctttaaa ataatcttga gctaaaaaca atcgttgagt gactttttca
     6241 aattgaattg taattttatt atcttttctt tccacacgtt gaacaaagac cttgtccaag
     6301 tatgatttaa ccaaaccaat ctctaaaaga taggctacta catctgggta ttctccaaaa
     6361 cggtctatca actcctcttg taactcttca taattgacac ggttgtcaat ttgacgaatt
     6421 ttcttgtaaa tttcaatctt atgtcgttga tcagaaatat aagtatcagg aagataggca
     6481 tcaatttgca aaatcaactc agcattccct ttggttcttg tgttagcgtt agcattaccg
     6541 tttcgtttag caatagcttc ctctaataac tgcgaataca attcaaaacc aacagaatca
     6601 atgaaaccag actgggattt tcctaaaaga tttcctgctc cacgaatcga aagatctcgc
     6661 attgcaatct taaagccaga gcccaattct gtaaatcctt taatcgcttc taatctcttt
     6721 tcagagactt cactgattga tttttctgga cgatacatga gataagcata agcaatacga
     6781 ttactacgac cgactcttcc tcttaactga tataaggttg acaagcccat atggtccgca
     6841 ttttcaataa ataaagtatt agcatttgga atgtccaccc ctgtctcaat aatagtagtc
     6901 gtcaccaaga tatcgtattg tccctcaata aagtctaata gagtattttc caactggact
     6961 tcactcattc gaccatgaac atatccaatc gaagcctccg gaatcaactc ctgtaattct
     7021 gaaaccttct gaacaattgt gtcaactttg ttgtaaagat aataaacttg acctccacgc
     7081 tccatttcac gcaagacagc atcacgaatg acactatcat tcttttccaa aacataggtc
     7141 tgaacaggat agcgattagt cggcggagtt tcaataacag ataaatctct gattcccagc
     7201 atagacatat ggagggtacg agggattggc gtagcggtca aggttaggac atccacttgt
     7261 ttcttcagtt ctttcaaagt ttccttatgc ttgacaccaa atcgctgttc ctcatcaata
     7321 atcatcaagc ccaaatcagc aaacacaaca tcttttgaca aaacacgatg tgttccaatc
     7381 aaaatatcga cttgaccgtt tttcaatttt tcaagtgttg cagtctgctc ttttttactt
     7441 ctaaagcgac tcaacacatc aatattaact gcaaaatttt ggaatcgttc cttaaaattc
     7501 gtatagtgct gttgcgctaa aaccgtcgtc ggaactagaa tgacaacctg tttgtgatca
     7561 ttgactgctt taaaggctgc acgcatagca acttcagtct ttccaaaacc aacatcccca
     7621 actaaaagtc gatccattgg ctgagaagcc tgcatatccc tcttgatttc ctcaatacta
     7681 cgaagttgat catccgtttc aacataaggg aaagcatcat caaaggcatc ttgatcatca
     7741 tcatcagctg agaaagcaaa acccttcaac tgactacgtt cagagtagag tttgattaaa
     7801 tcatcagcta tatcctctac ctggttctta accttttgct tggccttttt aaaatgaccg
     7861 tcatttaatt tattgagttt tggagcttta ccatcacttg aaatatattt ggacagtaga
     7921 tgaatctgtt ccacggggat agaaatttga tcaccatttt ggtattggac actgacataa
     7981 tcgcgatgaa ttcccttgat ttcaatggtt tcaattccta gatattgacc aatcccatgg
     8041 atatgatgga caacatagtc ccctttttca agttcattgt aatcttttaa tctctctgca
     8101 tttgaaacat gttgtcttcg aaaacgacgc tttaatttct tttgaaaaat ctcatgttca
     8161 gttatcaata aaatcttttc atctacaaaa tgaaaaccat gtctgagatt accctctatt
     8221 aaatttacag attctttaca gatacttgtc ttatctctag aatccaattt aatctgatat
     8281 tcctctaaca tatcctccaa tgttttactt cccattgaat tgctagactg cagaataatg
     8341 gtgtaatcca tttttttata tcgttcaatt tcttctttta gaaaagaaaa ctgattgaaa
     8401 aattcctgta taggatattg attgaattga taaattttgt caaatttgag atttcctaaa
     8461 cccttttgaa gattagagaa aaaggtcact ggactttgtt ttttatagat ttgttcaata
     8521 tcagaaaaat actgcatatc agaaaatgct ttactattct gtaattcttc tgtaaagtac
     8581 tgcgctaatt ctctttcaaa gacttcatac tgattcatca atttttgata atcatcaaag
     8641 aatattggag tatctttttc aatataatca aagacagtcc atgtcttatc atagcacaaa
     8701 gataaaaact tccgagaatc tgcatgactt tgtttttggt gaaaacttga aagaatttct
     8761 tctaggtatg atttcaaaat aggtgataaa gtttttgaaa tttgtttttc taaagctgac
     8821 tgtcctcgtt gataatcctt ttctctcaaa agcatatcac tagctggaaa gatagtgagt
     8881 tctgtcttat tttctttcga taattgtgtt tctacttcaa atgacctgat accatcaatt
     8941 tcatcaccaa aaaactcaat tcgacaaggt tctaactggg atatttcaaa aatatctaaa
     9001 atatctcctc gaagactaaa ttcgccctga gtttgtactt gagtaacttt ttgatagcca
     9061 ttttccttta actgatggat aaacgcgtgt tgagcatatt cttcaccaac tgagattttt
     9121 acaatactat ctttgaatgc attgggagac ggtaaaatca atcgacttgc tgcgatatta
     9181 caaactaaaa tccctttctt agatgaatca gtcaaaaaac gcaaggcttc aacccgtgaa
     9241 ataatttttt cctgtgaaga catcaaaaac tccaccatag gagcatcatc taccaaaaat
     9301 ggatagacga gttcctcacc caagatagaa ataagatcac taacaagtcc ttctgcttct
     9361 ccataagttg acgtcaataa cacaatccta tcttcttttt ctaaactgct tgcaattgca
     9421 agagccttag tagatgttga taaaccaagt attagttgtc ttttcttatc tgttaaattt
     9481 tgatgccatt ttttaatctg atcattttct gagaataaat ctaataaggt caccatttat
     9541 ccgttatacc tctgcattgt tttctcaaaa tttttctctt gtaaatagta ttttacagaa
     9601 tcgtcaactt tgtcaacaga ctgtaaaata ccgatataat catccctgtc aaacttactc
     9661 aaaacatgat gaacaactga cataccattt ttaggtcttc caattccaat cttaacacgg
     9721 ttaaagacct gagttcctat atgttgaata atagacttga taccattatg accacctgct
     9781 gagccttttg ctcttaaacg aattttccca acttccatgt caagatcatc gtaaatgata
     9841 agtaaatcgt caatatccaa accatagtaa gttaataaag catgaactgc ttttccactt
     9901 tcattcataa aggtcgttgg tttaaccaga taaatttttt ctccatttag gaaaaaggat
     9961 gctaggtcag cttgaaatat cttatcgtgt gtaaaagtga cattctgttt cttcgctagt
    10021 tgatcaatca acataaaacc aacattgtgt tttgtttcaa aatatttatc ccctggattt
    10081 cccaaaccta caagtaattt ggtcatttat ttttcctttc aaaagccaaa agggttggaa
    10141 tttttttcca acctaattga caccatttat taatttttag acattaaagc ggaattctat
    10201 gatgtcgcca tcttgaacga tatattcttt tccttcttca cgcaagcgtc cagcttcttt
    10261 tacggccttt tcagatccgt atttcactag atcttcatat gacatggtta ctgcacgaat
    10321 aaagcctttt tcaaagtctg agtggataat accagctgct tgaggagcct tcataccacg
    10381 tttgaaagtc caagcgcgaa cttctttttc accagctgtg aagtaagttc ccaatccaag
    10441 caagtggtaa gctgcacgcg tcaacttatc tacacctgat tctgtcaaac caatggcttc
    10501 aagaaactct tttttatctt catcatccaa ttcagaaatt tcttcctcag cacgcgcaga
    10561 aataacgact acttcagcat tttctgtcgc tgcaaattca cgaatttgtt tgacatagtc
    10621 gatagagtca ggttctgaaa ccacatcctc gtccacatta gctacataaa gaactggttt
    10681 agtcgtcaaa aggaaaagac ctttgacaac cttttgttcc tcatctgtaa attcaatggt
    10741 acgagctgat ttcccgtctt ctaggactgg tttaatcttt tgaagaacat tgaattctgc
    10801 tactgattct ttatcttttt gcgtacgtgc catcttttct acacgcgcat atcgtttgtt
    10861 cactgattct aagtcagcaa gaattaattc cagattaatt gtatcaatat ctgcaagtgg
    10921 atctacaaag gcgtcttcac gtccttgctc gcgcatcaca ttttcatcat caaaagcacg
    10981 aactacgtga acaatcgcat ctacttcacg aatattggcc aagaatttat tccctagccc
    11041 ttctcctttt gaagctcctt ttacaatccc tgcaatatcc gtaaattcaa atgttgtggg
    11101 aactgtcttt ttaggagtta tcatttcagt tagtttttgt aggcgttcat ctggaacttc
    11161 caccattcca acatttggat caatcgtcgc aaatgggtag tttgctgcct ctgctcctgc
    11221 ttttgtaatt gcattaaata gtgttgattt accaacgttt ggcaaaccaa cgatacctgc
    11281 tgtcaaagcc atatttctca ttctccgttt tcatttcaat ccctaatatt ataacacaaa
    11341 aagggataaa gtgctaaccc tctaactaag ggttctcagt caataatttt attcattttt
    11401 cgctcaaaat catatcgccc catcatgaca acatgctcac aattactgca ttttattttg
    11461 atatctgctc ctacacgtgt aatttcccaa cgattagcct ttttaccagt cgacttgatt
    11521 gtacaagcgt gtgatttttt catctcaaca aaatttccaa cttgatacat actactctcc
    11581 ttttcttttt cgattatatc ataaaagagg cgagccaggc tcaacctctt tcacttaatt
    11641 tgtacgaact ggtgtaatga gctgcatgaa gtcttcgtca gtatctgctg gcacaagagt
    11701 aaatggacga acagctgaga taaagctaat ggtcaccttt tcgctattta aagctttaag
    11761 agaatcaatc aagtaagttg ggttgaaact aatggtcaaa tcttcaccag taacctgatc
    11821 agtatcgatt tcttcgttta ctttaccaac ttctggagag tgaacatggg cgctaacaac
    11881 cccatcctta atttcaagtt tcacagtacc attttgagtc gcacttgata aaagacgggc
    11941 acgctccatt gactggcgta agtttaccac attaaaagta atagtagtgt taaagtctgt
    12001 tggaatcaag cgatctgtat caggatagtt tccttctagg agacgagtat agaagctaat
    12061 attttcgctt ctaaagagga tttggttatt ggcaaagaaa atctctacag tttcgatatc
    12121 atctgtaaat accgctgaaa attcgcgtag agaacggcta ggaattacga catcaaaatc
    12181 atcactattt ttttcaagag tcaatttttt ctggcttagg cgatgagagt ctgttgcaac
    12241 tgtttttaac tctttgtgtt gactcaatac gaagtggaca cctgttaaaa tcggacgact
    12301 ctcttgtgta cttgcagcaa aggctgtttc attaataatt ttcttgagta attttgtttc
    12361 aagtattaaa ggagtgcttg ctgaaatttc ttggattcgt ggatattgtt cgctatcttt
    12421 tccttttagg gtaatttctg atttgccact ggttaaaaca atttgatttt gttcaatttc
    12481 tttaaaatca agagttacat caggtaaact agatactaca ttgataaaga aagaagcttc
    12541 aagaaggatc gaacctaaag aagtaattaa caaaccagca tcttcatttt tttgagaaat
    12601 aaaattttca attgaaattt gaccatttga accaattaaa gtaatacctt cattggtcac
    12661 gtcaattttt actgttgata aaataggaat ggcattttta gaactaatag ctctcttagt
    12721 agtatttaat gcttgtagaa ataaattttt attaattgaa aaatgaatca tggattctcc
    12781 tttatttatt tttagtatta gaaagataat agtaataata gagtctgtga aatctgtgga
    12841 aaacagcctt taaacaagtc atatcaagtt ttttagcttg tttaaaaaat gtggataaaa
    12901 aagataaaaa actaaaagtt atccacaaat tatttgattt tctttttgat tgattcaatt
    12961 tctaaacgta aattatcgtc ttgatcaatc aaagatttta ttttggcatg ggcatgaatg
    13021 actgtggtat gatcttttcc cccaaattcc ttcccaattt ttggaagact attatctgtt
    13081 agttctctag ataaatacat ggctacttga cgggccaaaa caatattttg aaggcgtcta
    13141 cttcccttca tttctttgat actaacacca taaaagttac caacttcagt ttggatttta
    13201 tcaattggga tgacgagcat ttggctaaca tcttgtttgc gggctctaat ggcttctgca
    13261 gcaatatcaa tagtgatatc cttgattttt tttactctgg caattaaagt gatgtcgttg
    13321 atggctccct caagatctcg aacatttgaa tcaaattgcc cagctaggta ttctagagta
    13381 tcactttgga aattgtagcc taaatgttcc gttttacttt gtaaaatggc aatacgtgtt
    13441 tcaaagtcag ggggtgtgat agtttgtgtc aatccccaac taaaacgcgt gacaagcctc
    13501 tcctcgagcc cttctagatg ttttggacta cgatcactcg ttaggacaat ctgtttttgc
    13561 ttgtcatgaa gggcgttaaa ggtattgaaa aattcttcct gagttgcgac tttttttccg
    13621 ctgagtgact ggatatcatc gattaacaaa agatcaagac tacgataggt ctttttaaac
    13681 ttttccattt ccccaagtct taggtgatca agaaagtcat taataaagct ttcggcaggg
    13741 atatatttaa cacgcgcatt aggaatattt tttagaattt catttccaat agcgtttaat
    13801 aagtgagtct taccaaggcc tggtcctcca tagataaaaa gagggttata ggtcagagcc
    13861 aaatcttcag agacagctaa agcggctgac acagcccaaa catttccatc cccttgaata
    13921 aagttatcaa aggtatactt ttcttttaat cccgtatctg aataaggaat agatactaac
    13981 tttggactat agttataaag agttaaattt gtagcttctt caacttgtga gctagtcgta
    14041 tcttgaggtt tggtgaaaat atagtgggga gttatttcag cgtcataaat ttcaaaacca
    14101 gctactacaa taatatcttt tagttgtttt tcccagacca tttccatttc agagcgaggt
    14161 agaaatatag tggcaacatt ttcctctacc ttgatgagtt cagcttgaat agcatagaaa
    14221 tcatacatgg atcgagtcag tctttcttgt gcaaattcta atatacgatt ccaaaattgt
    14281 ttttctttca atcctttctc ctcctttact atttaaaagt ttaatactag agatatttta
    14341 ccatagatag caagaatttt ccacaagctg tgaaaaataa tccacaatgt taccaaactt
    14401 tatccacagg ttggggataa aagaagaaat tattgattta ttaagctttt tattgaaaaa
    14461 catagtggat aaccttgtga gataaaaaaa taaaagaaca gccttatttc aggctgttga
    14521 taattctact atattcttct tgatttgaaa aagaaataat gatttttcca ctgtcttttt
    14581 tagatagttt aatttctaca tctaatccga gtagttttct taactgtttt tcttcatttt
    14641 gtatgaaatg attagttttt tgctgtttct tttgtttttt ctctgtcaga agagcttcta
    14701 atttccttac agaaatatct tcttctataa tccgttgaaa gaaatagtct tgttgttcct
    14761 tatttaaccc aactagggaa cgcgcatggg cttgtgatag tttgccattt tctacttctg
    14821 aaagaatctg ttctggcaag gaaagtaaac gaatggagtt gctgatatat ggacgagact
    14881 tgcccatctt atctgcaatt tcagcatggg tgaatccttt ctctacgaga gattcatagg
    14941 cgcgtgcttc ttctattggg tttaaatttt ctctctgtaa attttcaata atggactgga
    15001 ccatcatctc ttggtctgaa atctgtttaa caacagctgg gatagaccgt agaccagcta
    15061 aaagtgaagc ccgatagcgt ctctctcctg caaggatttc ataaccaata acaggagatt
    15121 gacgaacaat aatcggttga atgaccccat tttctttgat agactgtgct agttcatcta
    15181 gtttttctct atcaaattct tttcggggtt gatagggatt tttttgtata tctgtgatag
    15241 aaatcatttc aaatttttcc atgattctac actaacacat cttttctctt atgtaaagct
    15301 ttctttacat agatgtcaat taagattcta aatcacctga actcttgtta agtttgatag
    15361 aggtagtttc ttctttcccg ttacgatagt aggttatctt aatggtgtct ccgatagaat
    15421 ggttgtaaag agcactttgt aagtctgttg atgaagcaat ctctttgtca tctacttttg
    15481 taattacatc gtatttttca aggtgaccat tggcaggcat attactttgt accgaacgaa
    15541 caactacacc agatgtaaca ttacttggaa tattgagtct tctgatgtcg cttgtactca
    15601 cattagataa attaaccatc tggattccca aagctggacg cgtcactttt ccgttttttt
    15661 ctaactgttc aataatattg atagcatcat ttgcaggaat tgcgaaacca agaccttcta
    15721 cagatgttcc tccatttgta gcaattttac ttgaggtaat tccgataacc tgcccttgaa
    15781 tattgatcag tgggccgcca gagttacctg ggttaatagc agtatcagtt tggatggctt
    15841 ttgtagaaat agcttgtcca tcttccgatt ttaaggatac atttctattg agactggata
    15901 cgataccttg agtgacagta tttgcatatt cagaacctaa cgggctaccg atggcaatag
    15961 cagtttctcc tacagttaac ttactagaat caccaaactc agctactgtt gtcacttttt
    16021 ctgaagagat ttttacgaca gcaatatcag agaaagtgtc agctccgaca atttctccag
    16081 gtactttagt cccatctgac aatcgaatat ctactttgct ggcgccattt ataacgtgat
    16141 tgttggtgac gatgtaagct tctttatcat tctttttata aataactcca gatccttcac
    16201 tagagattcg ctgagaatct gtgtcagtat catcattgcc aaatacgcta ttttgtctgt
    16261 ttgccgaata agtaataaca gaaacaacag catcttttac tttgttaaca gcctgtgttg
    16321 ttgaattttc gttcttatag gcagtttgtg taatagtact attgttgtta gagttgttta
    16381 cactactttt ttgagttagt tgagttattg aaaaactacc caaggctcca ctaaaaaagc
    16441 taatgacgat aacgactaat aattgaaacc attttttgta aaatgttttt agatgtttca
    16501 tatttgcctc catatgtttg aattactgaa agtataaact gactagctta attataactt
    16561 aaacacaaaa gttttacaca aactgtggat aactcttttg aaactgtgat tttcttaatt
    16621 gaaatctatt ttttattttg tgaataagat gtgaaaaaat agagaatatg ttagaataga
    16681 gtcatgaaaa ttaaagttgt aacagttggg aaactgaaag aaaagtattt aaaagatggt
    16741 atcgcagagt attcaaaacg aatttctaga tttgctaagt ttgaaatgat tgagttatca
    16801 gatgaaaaaa caccagataa ggccagtgaa tcagaaaatc aaaagatttt agaaatagaa
    16861 ggtcagagaa ttttatcaaa aattgctgac cgtgatttcg ttattgtgtt agccattgaa
    16921 gggaaaactt tcttctcaga agaatttagt aagcagttag aagaaacttc tataaaagga
    16981 ttttctactc ttacttttat tattggggga agtttaggat tgtcatcatc tgtaaaaaat
    17041 agagccaatc tttctgtcag ttttggtcgc ctaaccttac cccatcagtt aatgagacta
    17101 gttcttgttg aacaaatcta tcgcgctttt acgattcagc agggattccc ctaccataaa
    17161 tagaaaattg acttttaatt gaatttttgg tagaataatt gtattaggtc tcatagctca
    17221 gctggataga gcattcgcct tctaagcgaa cggtcgcagg ttcgaatcct gctgggatca
    17281 atataatagc aaagctggga attttcccgg cttttttctt aaaaaagtac actttgggag
    17341 aaaaaaatga cagttgagag aattttatct aaaacgaaat tccattttgt ataatggttt
    17401 ttgtaagtta gcttacaaga aaaaacattt taggagattt tattatgaaa aacacagtta
    17461 aattggaaca gtttgtagct ttgaaggaaa aagacttaca aaagattaaa ggtggggaga
    17521 tgaggttgtc aaaattcttc cgtgatttta ttttacaaag aaaaaagtaa tgaaataagg
    17581 ggaaagagta atggatttat ttggatttgg gacggttatt gttcattttt taattattag
    17641 tcacagttac cattttattt gtaaaggtca aataaataga aaagaattat tcgtttttgg
    17701 tgcttataca ttactaacag aaatagtatt tgattttccc ttatatattc tatatttaga
    17761 tgggttaggg attgaaagat ttttatttcc tttgggatta tattcctatt ttcgatggat
    17821 gaaacagtat gagagggata gaggactatt cctaagttta ctactatctc ttttatatga
    17881 gagcactcat aactttctgt ccgtaacttt ctcctctata acaggagata attttgtttt
    17941 acaatatcat ttcccattct ttttcgttgt gacggtgtta acctattttg ttacattaaa
    18001 aatcatttac tatttccatt tggaactagc ctattttgac gaggactacc tttatccttt
    18061 cttgaaaaaa gtattttttg ctttactatt gctacatatt gtatctttcg tttcagatat
    18121 ggtaagtacg attaaacatt tgaatagttt tggaagtatt ttgtcatcta ttgtctttat
    18181 ctctctcctt ttgaccttct ttgcaatgaa ttctcataaa gttcaaatgg agaaagagat
    18241 tgctttgaag cagaagaaat ttgaacagaa acatttacag aattacacag atgaaattgt
    18301 tggtctgtat aatgaaatcc gtggttttcg acatgattat gctggaatgc ttgtcagcat
    18361 gcagatggca attgacagtg gtaatttaca ggaaattgac agaatttaca atgaagtttt
    18421 agtcaaagca aatcataaat tgcgttcaga taagtacact tactttgatt tgaacaacat
    18481 agaagactca gctttacgaa gtttggttgc tcagtcaatt gtctatgctc gaaataatgg
    18541 tgtagagttt acactggaag taaaagatac gattaccaag cttccaattg aactattgga
    18601 tttggttcgt atcatgagcg ttttattgaa taatgctgtc gaaggatcgg ctgatagcta
    18661 taaaaagcag atggaagtag cagttattaa gatggaaact gaaacagtta ttgtgattca
    18721 gaattcatgt aaaatgacga tgactccttc aggagatcta tttgccttag gattctccac
    18781 taagggaaga aatcgcggag tcggattaaa taatgtgaaa gaactactag ataagtacaa
    18841 caatattatt ttagaaacag agatggaagg cagtacattt agacaaatca ttagatttaa
    18901 gagggaattt gaatgaaagt tttaatttta gaagatgtta ttgaacatca agtgagacta
    18961 gagagaatat tggatgaaat ttcgaaagaa tcgaatattc caatatcata caagacaacg
    19021 ggaaaagtcc gtgaatttga agaatacatt gaaaatgatg aagtaaatca gctttatttc
    19081 ctagatatcg atattcatgg aattgagaaa aagggatttg aagtggctca gctcattcgt
    19141 cattacaatc cttacgctat tatcgtcttt atcactagtc gatcagagtt tgcgactcta
    19201 acctataaat accaggtatc agccctagat tttgttgata aggatatcaa tgatgagatg
    19261 tttaagaaga gaattgagca aaatatcttc tacacgaaga gtatgttact tgaaaatgaa
    19321 gatgttgtag attatttcga ctacaattac aagggaaatg atttaaaaat tccttaccat
    19381 gatattttgt atattgaaac aacaggggtc tctcataaat tgcgcattat tggtaagaat
    19441 tttgcaaaag agttttatgg taccatgaca gatattcagg aaaaggacaa acatactcag
    19501 cgattttatt ctcctcacaa gtcatttttg gtaaatatag gcaatatcag agaaattgat
    19561 cgaaaaaact tagaaattgt tttctatgaa gaccatcgtt gtcctatttc aagattaaaa
    19621 attagaaaat taaaagatat tttagagaaa aaatctcaaa agtgattgac aattagcaag
    19681 aaattgatat aatggttata tctgctacag atagaaggtc cgttggtcaa ggggttaaga
    19741 caccgccttt tcacggcggt aacacgggtt cgaatcccgt acggactatt ttatccgcca
    19801 tagctcagtt ggtagtagcg catgactgtt aatcatgatg tcgtaggttc gagtcctact
    19861 ggcggagtat agataaaagg gaacacagct gtgttcctct ttttgtatca atttgtatca
    19921 ccaagcattt tcataaggaa gtctgttatt tcttgagaac tttctttttt tccatgtgca
    19981 atccaagttt ggcagacacc aaaaagtgca tgagttagat agatgctact atattctaat
    20041 tcggtggtat ttagattcag ttgcataaat cgcttttgta aatctgtact aagcatgata
    20101 tgaagtttat ttcgtaagaa attttggatt tctttagtcc cattttcaga aagaagggca
    20161 gccagaagtg gttctgactc tagatattca aaaacttcta aaatagcgtc tcttttgtga
    20221 tgagcatgtt tttgaaaaat atattcaaat gtatggaata gcttgctttg atagtgctca
    20281 atcatatcat acttatcctt atagtgagta tagaagctgg aacgactaat tccggctttt
    20341 tctactaatt tgacagtaga aattttatca aatggctgtt ccatcagtaa ttgtaccata
    20401 gcattttcaa tagttcgctt tgtttttaag cgtttgttac tttcttgcat atttcctcct
    20461 tgtaaacaaa ttagactata tgtttaaaaa tagatttttt atcttgtaat ttagattttt
    20521 taatgtataa tctattatat caaaatttta gacaatatgt ttaaaaaagg agaaactaag
    20581 tttaaagaat ggaaagcaat ttaaaaaaaa ccaaccttta ttattgtcat gatcgggatt
    20641 tctcttattc cagatctgta caatatcata tttttgtcat caatgtggga tccatatggg
    20701 caattgtctg acttacctgt ggcagttgta aataatgata aagaggcttc ctataatggt
    20761 aatactatgg caataggaaa agacatggtg tccaatttaa aagaaaataa aaccttggat
    20821 tttcattttg tagatgaaga ggaaggaaag aagggattgg aagatggcga ttactatatg
    20881 gtagtgactt taccaagtga tttatctgaa aaaacaacta cattatccaa tattcaatcg
    20941 acagcagctt atcaatcatt gacaagtgag caacaaactg agataagtga ttctgtatct
    21001 caaaattcaa ctgatagtat tcaatcggct cagtcaattg tagctttagt acaagattta
    21061 cagggaagtt tagaaaactt acaaaatcaa tcttctaatc tttcgacttt aaaaaatcaa
    21121 tctaatcaag tatcacctat tacttctact tctttgatag gattgtcaag tggattaaca
    21181 gagatacaag gagatgttac tagcaaatta gttcctgcca gtcagtcgat tgcatcaggt
    21241 gtaaacgcat atactacagg tgttgataaa gtttctcagg gcgcaagtca actaagtgaa
    21301 aaaaatgcca ccttgacagg tagtttggat aaactagttt caggctcaaa caccttgaca
    21361 caaaaatctt ctagattgac agcaggagtt ggttaattac aatcaggatc tgggcaatta
    21421 gcagacaaat ccagtcagtt actttcaggt gcttctccat tagagaatag agctaataaa
    21481 ttggcagatg gatctgggaa actagcagaa ggtggaacaa agttaacttc tggattggaa
    21541 gatttacaga caggacttgc ttctttagga caaggactag gtaatgctag tgatcaactc
    21601 aaatcagtat caacagaatc taaaaatgca gagattttgt caaatccact caatctttca
    21661 aaaacagaca atgatcaagt tcctgtaaat ggaatcgcaa tagctcctta tatgatatca
    21721 gttgctcttt ttgttgcagc aatatcaaca aatatgatat ttgcgaaatt gccttcagga
    21781 cgtcatccag agagccgttg ggcttggttg aaatctcgag ctgaaataaa tggtattata
    21841 gctgttttgg caggaatttt ggtatatgga ggagttcagc ttattggttt aactgctaat
    21901 catgagatga gaatatttat tctcatcatc ctaacaagtt tagtattcat gtctatggtg
    21961 accactttaa caacgtggaa tagccgtata ggagcttttt tcttacttat tttgctttta
    22021 ctacagttag catcaagtgc aggtacttat ccacttgctt tgacaaatga tttctttaga
    22081 tctattaatc cctggttacc aatgagctat tcagtttcgg gattacgaca aacaatctct
    22141 atcaacaagt cattttccta gctgtcatac tagctctatt tactggttta ggtatgctag
    22201 cctatcaaca taagaaaatg gaagaagatt aaaaaaatcg accgattaat gaactgcacc
    22261 ccaaaagtta gacagaaaaa atctaacttt tgaggtgttt tattatgaaa
//
LOCUS       DAVAZT010000037        21881 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVAZT010000037 DAVAZT010000000
VERSION     DAVAZT010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21881
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.037"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            244..1110
                     /locus_tag="VQT45_001351"
     CDS             244..1110
                     /locus_tag="VQT45_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2359668.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLHALAKKLKVSMDYFFDEQVVEKVEELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKIYMEWIKSLIDFYFYGQKEDAIVRLEGVLSQLSVSDLNYLQVSNTLFN
                     FYYDIGDLGRFNKIREKLEYQVNHLNLSTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKAYRTNYLLADLYLLMGNVSENFSSKSSVKEYFETAYFLYKLEENMSMT
                     LKVEHYIADITE"
     gene            1447..2004
                     /locus_tag="VQT45_001352"
     CDS             1447..2004
                     /locus_tag="VQT45_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase family
                     flavoprotein"
                     /protein_id="HET2359669.1"
                     /translation="MDKKNLLVLVTGSVGASNVDTYLYYIKKFYNVKVILSENSKKFI
                     SKELISYFCDKVYDEIFVEEVVPHVFLPYESDLLLILPATANVIGKIANGIADDLVTA
                     TVLNFNKKIIFCPNMNSTMWDNHIVQRNVSILKELGHIFLFESKKTYEVGLRKAIDST
                     CSMLQPQSLVKELIKLENIVLEEGH"
     gene            2225..3331
                     /locus_tag="VQT45_001353"
     CDS             2225..3331
                     /locus_tag="VQT45_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HET2359670.1"
                     /translation="MINKKIQQVVLESLQNFLNGNFISPCVVYDFGLLETVLDEFKNQ
                     IPVTFNYQLFYAVKANSNEKILEFLVDKIDGVDVASLSELDVAKKFFPPTQISVNGPA
                     FSYETLYNLIKKQYKVDINFLEHLQQFSPKESVGIRVTEPDELNNRMSRFGINICSDN
                     WTSNLQNPLITRLHFHFGEKDDKFIVKLDKILFKLQEINKLREVREINLGGGFMKLFM
                     ENRLKEFFLSLMEIYKKYDIDSTVTTIIEPGSAITSFSAYMITSPVNVSEVNEQQVIT
                     LDTSIYTNTLWFVPHIITTLNSSSKERYSTILYGNTCYEHDKYKMKVSLPRLTQNSSI
                     VFFPVGAYIKSNHSNLHRNDFMREVYLWTKNLTY"
     gene            3307..4698
                     /locus_tag="VQT45_001354"
     CDS             3307..4698
                     /locus_tag="VQT45_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359671.1"
                     /translation="MDKKLDILDKVKEYLGNKTTQILDNQYKEFLKLNDIRRAFGISE
                     KVLNNSFNFTSKEFNDLINNENYLFEYACRIREEWRKKCFNHSYRFLCSPIITDDFLN
                     TKTLRSSQIEYKYERYLSKSSIGDRAVDGFVSFNTLTANGMSAIKLCLEILNSIFFKK
                     KIDLLYSTGYYETRFLLNNLAKSGISCYEVSNCELDKDKFYNVFMMEPNRADLTLQKT
                     DFKIVEYFVKYKNNSIKVVILDISYQGSNFKLVEFLEKFKFANVIIFVVRSLIKLDQM
                     GLELTNGGIIEVFIPNHLRKLKNFIEEEFNKFRNSHGANLSLYEYCLLDNSLTLKNDW
                     NYSDLVMKFTSNFYADIKDLFMENSDIEIIHEEGVPFVFLDLIGEGKKEYEMFFQWLN
                     FFYKQLGITLYARNSFGFRNLTVEYFGIIGTERYIFKICPGVYKGLSYYLMKFLLKSF
                     SNEYLKTTDEVNR"
     gene            4695..5873
                     /locus_tag="VQT45_001355"
     CDS             4695..5873
                     /locus_tag="VQT45_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2359672.1"
                     /translation="MKNLIKLLIIRLIVNLADSVFYIVALWHVSNNYSSSMFLGIFIA
                     VNYLPDLLLIFFGPVIDRVNPQKILIISILVQLAVAVIFLLLLNQISFWVIMSLVFIS
                     VMASSISYVIEDVLIPQVVEYDKIVFANSLFSISYKVLDSIFNSFASFLQVAVGFILL
                     VKIDIGIFLLALFILLLLKFRTSNANIENFSFKYYKREVLQGTKFILNNKLLFKTSIS
                     LTLINFFYSFQTVVVPIFSIRYFDGPIFYGIFLTIAGLGGILGNMLAPIVIKYLKSNQ
                     IVGVFLFLNGSSWLVAIVIKDYTLSLILFFVCFMSKGVFNIIFNSLYQQIPPHQLLGR
                     VNTTIDSIISFGMPIGSLVAGTLIDLNIELVLIAISIPYFLFSYIFYTDNGLKEFSIY
                     "
     gene            6298..6531
                     /locus_tag="VQT45_001356"
     CDS             6298..6531
                     /locus_tag="VQT45_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000623387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2359673.1"
                     /translation="MISIDLGGTNIKITVLSNDGEIETLWSITTDTSEKGSQIISDII
                     SSIKNKLTERNIPDSDLLGIGMGSCSSYFPCKS"
     gene            6814..8763
                     /gene="mutL"
                     /locus_tag="VQT45_001357"
     CDS             6814..8763
                     /gene="mutL"
                     /locus_tag="VQT45_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HET2359674.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKIQITDNGYGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(9088..9555)
                     /locus_tag="VQT45_001358"
     CDS             complement(9088..9555)
                     /locus_tag="VQT45_001358"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HET2359675.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(9556..10761)
                     /locus_tag="VQT45_001359"
     CDS             complement(9556..10761)
                     /locus_tag="VQT45_001359"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HET2359676.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(10781..11416)
                     /gene="ribE"
                     /locus_tag="VQT45_001360"
     CDS             complement(10781..11416)
                     /gene="ribE"
                     /locus_tag="VQT45_001360"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HET2359677.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(11401..12501)
                     /gene="ribD"
                     /locus_tag="VQT45_001361"
     CDS             complement(11401..12501)
                     /gene="ribD"
                     /locus_tag="VQT45_001361"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HET2359678.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(12636..12750)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            12907..13500
                     /gene="ruvA"
                     /locus_tag="VQT45_001362"
     CDS             12907..13500
                     /gene="ruvA"
                     /locus_tag="VQT45_001362"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HET2359679.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDGLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            13510..14073
                     /locus_tag="VQT45_001363"
     CDS             13510..14073
                     /locus_tag="VQT45_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HET2359680.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRDFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            14070..14747
                     /locus_tag="VQT45_001364"
     CDS             14070..14747
                     /locus_tag="VQT45_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2359681.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     VGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(14888..15919)
                     /locus_tag="VQT45_001365"
     CDS             complement(14888..15919)
                     /locus_tag="VQT45_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HET2359682.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGRALFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNAGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(16174..16857)
                     /locus_tag="VQT45_001366"
     CDS             complement(16174..16857)
                     /locus_tag="VQT45_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HET2359683.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASVFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(16869..17813)
                     /locus_tag="VQT45_001367"
     CDS             complement(16869..17813)
                     /locus_tag="VQT45_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET2359684.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            17945..20776
                     /gene="uvrA"
                     /locus_tag="VQT45_001368"
     CDS             17945..20776
                     /gene="uvrA"
                     /locus_tag="VQT45_001368"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HET2359685.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAIKASSVEQIVDKVLELPERQRLQILSPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDNSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPNASKTLHEGALAPWNPISSNYYPNMLEQAMTAFGVAMDKP
                     FEDLSEEDKNLILYGSDGKKFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCHGYRLNDQALSVRVGGEQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            20769..21830
                     /locus_tag="VQT45_001369"
     CDS             20769..21830
                     /locus_tag="VQT45_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET2359686.1"
                     /translation="MNKRVQAFLAKMQEKELDGVIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
BASE COUNT         6639 a         3842 c         4442 g         6958 t
ORIGIN      
        1 gaaaggggct gaaagaacta ggggaacagt tgtaattaga aggtgatagg tatgaaaagt
       61 ggcgttgaag ctggataagt ttataaagag tttgaatgaa gaaatgaaaa gtaaataagt
      121 tgatgatgaa ttgcaaaaat agattttata tacaatttgt atctttcaaa tcattgattt
      181 gaattttaga tttaatcatg ttacaattaa aaatgaaatc aaatagaaga ggaagatgca
      241 aacgtgggca cactattagc aacaagatta aaaaatagac gaaaagaatt aaaaatgtct
      301 cagcgagaac tagctgaagg tatctgtaaa caggggcaaa tcagtcgatt agagagcgga
      361 gagtttactc ctggagcaga tttcttgcat gcccttgcta agaagttaaa agtcagtatg
      421 gattattttt ttgatgagca ggttgtagag aaagttgagg agttatcaga atttaagaaa
      481 ttagcacaga catttattac aaatcgcaat tatgagtctt tgaaatatat atatgaattg
      541 gagaatgtaa aagctcaccg cctatcttta gcagataaaa tctacatgga atggataaaa
      601 tctctgatag atttttattt ttacggacag aaagaagatg cgattgtacg attagagggg
      661 gtattatcac agttaagtgt atctgatttg aactatctcc aagtttcaaa caccctattc
      721 aatttttatt atgatattgg agatttaggt cgtttcaata aaattcgtga aaaactagag
      781 tatcaagtaa atcacctcaa tttgagtaca atcgaagagt tagaactatc tattaagttt
      841 aactacaacg tttgtcgtta tctatggtta cagaaaaata ttgaagaagc tattactaaa
      901 attacagcta ctataaaaca atgtaaggct tacagaacga attatctttt ggctgatttg
      961 tacttattga tgggaaatgt aagtgaaaat ttttcttcta aaagttcggt gaaagaatat
     1021 tttgagacgg catattttct atacaaactt gaggagaaca tgtcaatgac tctgaaagtt
     1081 gagcattaca ttgcagatat aacagaataa tgaatacggt gttcaagtga gcatcgtttt
     1141 tcaaacctag ttcagataca aaaaagtatc aaataaaaaa aaataaaaaa acattataaa
     1201 aacaattgac aagctaattt tgaagtgata aaataaatgc aagaaaacaa aaggagaggt
     1261 atatgagaag tttgtttaag aaaatagttg ctgtattagt tattggctta attctgttag
     1321 gaattgcgag aacacctcaa gttcataaga tggctagagg gattgatcct ggtcctgcga
     1381 attttattta gaaatcaatt tctactaatt gagtactaat tgagtattaa tgggtaaaaa
     1441 gattgtatgg ataagaaaaa tttacttgta ttggttactg gttcggtagg tgccagtaat
     1501 gtagatacat acttatatta tataaaaaaa ttctataatg ttaaagtgat actttctgaa
     1561 aattctaaaa aatttataag taaggaatta attagttatt tttgtgataa agtttatgat
     1621 gaaatatttg ttgaagaggt agttccgcac gtttttctgc catatgaatc tgacttactt
     1681 cttattttac cagctacggc aaatgtgatt ggcaaaattg ctaatggtat tgctgatgat
     1741 ttagttacag caactgtttt aaactttaat aaaaaaataa ttttttgtcc caatatgaac
     1801 tctactatgt gggacaatca catagttcaa agaaatgtat caattctaaa ggagttggga
     1861 catatatttt tatttgagtc taaaaaaaca tatgaggtag gattgcgtaa agcaatagat
     1921 tcaacatgtt caatgttaca accacagtcg ttagtaaaag aacttatcaa attagaaaat
     1981 attgtccttg aagagggaca ttaaaaacta ctgagaatat taaggagggg aaaaaatgga
     2041 aaattcatca atcgatgtag atatgctgtt ggaagaattg acacaagaag caatggtcgt
     2101 tgttgctgtt gataaggact gttaatttaa acttatggca atatatgaaa ggttactgga
     2161 tgttttaaat tatgcaggca gtagcctttt attatataca aatggataaa gtaaggataa
     2221 tacaatgatt aataaaaaaa tacaacaagt tgttttggaa tcattacaga attttttgaa
     2281 tgggaacttc atttcgcctt gtgtagtcta tgattttggc ttgctggaaa ctgtacttga
     2341 tgaatttaaa aatcaaattc ctgtaacatt caattaccaa cttttttatg ccgttaaagc
     2401 aaattcaaat gagaagatac ttgaattctt agtagataaa attgatggag ttgatgtggc
     2461 gtcattatct gaattagatg tggctaaaaa atttttccca ccaactcaaa tttctgttaa
     2521 tggtcccgca ttttcttatg aaactttata taatctgatt aaaaaacaat ataaagttga
     2581 tattaacttt ttggaacatc ttcaacaatt ttccccaaaa gaatctgttg gaataagagt
     2641 aacggagcca gatgaactta ataatcgtat gagtcgattt ggaataaata tttgcagtga
     2701 taattggact agtaatttac aaaatccttt aattacacga ctgcattttc attttggaga
     2761 aaaagatgat aaatttattg ttaagttaga taaaatatta tttaagttac aagaaattaa
     2821 taaacttaga gaggttagag aaataaatct tggaggcggt tttatgaaat tatttatgga
     2881 aaatcgtttg aaagaatttt ttctatcact tatggaaatc tataaaaagt acgatattga
     2941 tagtactgtg actacaataa tagaaccagg tagtgcaatt acttcatttt ctgcctatat
     3001 gattactagc ccagttaatg ttagtgaggt gaatgagcag caggttatca cgttagacac
     3061 atcaatatac accaatacat tatggtttgt tccgcatatt attacaacgt taaattcaag
     3121 tagtaaagag cgttatagta ctattctcta tggtaatacc tgttatgaac atgacaagta
     3181 taaaatgaaa gtttcgcttc caaggttaac tcaaaatagc agtatagtgt tttttcctgt
     3241 aggagcttat ataaaaagca atcattcaaa tttacatcgt aatgatttta tgcgggaggt
     3301 atatttgtgg acaaaaaact tgacatatta gataaagtta aggaatattt aggaaataaa
     3361 actactcaaa ttctggataa tcaatataaa gaatttttga aacttaatga tataaggcga
     3421 gcgtttggta tttcagaaaa agtattaaac aattctttta attttacgag taaagaattt
     3481 aatgatttaa ttaataacga aaattattta ttcgaatatg catgtagaat tagagaggaa
     3541 tggagaaaaa aatgctttaa tcattcttat cgttttctat gctcacctat aattacagat
     3601 gattttctta acacgaagac attgagaagt agccaaattg aatataaata tgagcgatat
     3661 ttatcgaaaa gttcgatagg cgatagagcg gttgatggct ttgtttcctt caatacttta
     3721 acagctaatg gtatgtctgc tattaaacta tgtcttgaga tattaaactc tattttcttc
     3781 aagaagaaga ttgatttatt atattcaacc ggatattatg aaacaagatt tttattaaat
     3841 aatcttgcta aatcaggtat tagttgctat gaggtaagta attgtgaatt ggataaagat
     3901 aaattttata atgtattcat gatggaaccc aatcgagccg atttaacatt acaaaaaact
     3961 gatttcaaga tagtagaata ttttgttaag tataaaaata attcaataaa agtcgttatt
     4021 ttagatattt catatcaagg ttctaatttt aaattagtag aatttttaga gaaatttaaa
     4081 tttgcgaatg taattatttt tgtggtacga tctttgataa aattagatca aatgggatta
     4141 gaattgacaa atgggggaat aatagaagtg tttattccta atcatttgag aaagttgaaa
     4201 aattttattg aagaggaatt caataaattt agaaattctc acggagctaa tctaagcctc
     4261 tatgaatact gtttgcttga taattcttta accttaaaaa atgattggaa ctattctgat
     4321 ttagttatga aatttacgag taatttttat gctgatataa aagacttgtt catggaaaat
     4381 tctgatattg aaatcatcca tgaagaggga gtaccttttg tatttttaga tttaataggt
     4441 gaaggtaaaa aagaatatga aatgtttttt caatggttaa acttctttta caaacagctt
     4501 ggaatcacat tgtatgctag aaatagtttt gggtttcgga atctaacagt agagtatttt
     4561 ggaattattg ggacagaaag atatatattt aagatttgtc caggtgttta taaagggtta
     4621 agttattatt tgatgaaatt tttattaaaa tctttttcaa atgaatattt aaaaactact
     4681 gatgaggtta atagatgaaa aatttgataa agttgctaat aattagattg attgttaact
     4741 tagcagacag tgtattttat atagtagcat tgtggcacgt tagcaataat tattcttcga
     4801 gcatgttctt aggaatattt attgcagtaa attatctacc ggatttgtta ctaatctttt
     4861 ttggaccagt tattgacaga gtaaatccgc aaaaaattct tataatatca attttggttc
     4921 aattagcagt ggctgtaata tttttattat tattaaacca aatatcattt tgggtgataa
     4981 tgagtctagt gtttatttca gtaatggcta gctccataag ttacgtgata gaagatgtgt
     5041 tgattcctca agtggtagaa tatgataaga ttgtatttgc aaattctctt tttagtattt
     5101 cgtataaagt attagattct atttttaatt cattcgcatc atttttacag gtggcagtag
     5161 gatttatttt attggttaag atagatatag gcatattttt acttgctcta tttatattgt
     5221 tgttgttaaa atttagaact agcaatgcga atatagaaaa cttctctttc aaatattaca
     5281 agagagaagt gttgcaaggt acaaagttta ttttaaataa taaattatta tttaaaacca
     5341 gtatttcttt aacgcttata aacttttttt attcatttca gacagtagtt gtaccgattt
     5401 tttctattcg atattttgat ggtccgattt tttatggtat ttttttaact attgctggtt
     5461 tgggtggtat attgggaaat atgctagcgc caatcgtaat aaaatattta aaatcgaatc
     5521 aaattgttgg tgtatttctt tttttgaacg gctcaagttg gttagtagca attgttataa
     5581 aagactatac tttatcactt attttatttt tcgtttgttt tatgtctaaa ggagtcttca
     5641 atattatttt taattcgttg taccaacaaa tacctccaca tcaacttctt ggtagggtaa
     5701 atactaccat tgattctatt atttcttttg gaatgccaat tggtagttta gttgcaggaa
     5761 cgcttattga tttgaatatt gaattagtgt taattgctat tagcatacct tattttttgt
     5821 tttcttatat tttttatacg gataatggat tgaaagaatt tagtatatat tagaaatgtt
     5881 tatgttcatt caaaagcata atgactataa ctgaaaaaga aaagtgatat ctttaaggtt
     5941 gttcttcttg gtggtgagat tcgtgagaca acccaagctt ttgtcggaaa gattaccaat
     6001 gctttgatgg ataggatgta ctttagcaag atgtttttag tggtaacggt atcgtggatg
     6061 gacgtgtaat aacctcttct ttcgaggagt attttactaa aaaactagcc ttggagcgtt
     6121 ccccagaaac ggacttactc attgactctt caaagatttg gggagaagat tttgcttcat
     6181 ctgttccttg aaaaaagtca cagcagtcat cacagacgat agtactgaac aaaactatga
     6241 agagttagaa atttatacgc aggtgattgt ataaaggatc tggaaataga taagaagttg
     6301 attagtattg acctaggtgg tacaaatatt aagattactg ttctttcaaa tgacggtgag
     6361 attgaaactt tgtggagtat tacaacagat acaagtgaga aaggttctca aattatatcg
     6421 gacatcatca gttctattaa aaataaattg accgaacgga atattcctga tagcgacctt
     6481 cttggaatcg gtatgggaag ttgctcatca tactttcctt gtaaatcata ggggctataa
     6541 actctccgtc tacttgtcct gcaacaattg aagtctgctc aaaacgccgt ccgctaatct
     6601 tttcatagac tttctccctt ttaggagcct agctttctag tttgttcttt gatttttatt
     6661 gagtatacca ctattttact ccctctggca agggactttg tctatgtgga gggattgggc
     6721 tcctatgtgg tggagctttt ctgttctttc tgaaatatgg tataatagca ctaatcaatt
     6781 tctaggaaaa tagatacgga aaggggctga aagatgtctc atattattga attgccagag
     6841 atgctggcaa accaaatcgc agctggagag gtcattgaac gtcctgccag cgtggtcaaa
     6901 gaattggtag aaaatgccat tgacgcgggc tctagtcaga ttatcattga gattgaggaa
     6961 gctggtctca agaaaatcca aatcacagat aacggttatg gaattgccca cgatgaggtg
     7021 gagttggccc tgcgtcgcca tgcgaccagt aagataaaaa atcaagcaga tctctttcgg
     7081 attcggacgc ttggttttcg tggtgaagcc ttgccttcta ttgcgtctgt tagtgtcttg
     7141 actctgttaa cggcggtgga tggtgctagt catggaacca agttagtcgc gcgtgggggt
     7201 gaagttgagg aagtcatccc agcgactagt cctgtgggaa ccaaggtttg tgtggaggat
     7261 ctctttttca acacgcctgc ccgtctcaag tatatgaaga gccagcaagc ggagttgtct
     7321 catatcattg atattgtcaa ccgtctgggc ttggcccatc ctgagatttc ttttagcttg
     7381 attagtgatg gcaaggaaat gacgcggaca gcagggactg gtcaattgcg ccaagcaatc
     7441 gcagggattt acggtttggt cagtgccaag aagatgattg aaattgagaa ctctgaccta
     7501 gatttcgaaa tttcaggttt tgtgtccttg cctgagttga ctcgggctaa ccgcaattat
     7561 atcagcctct tcatcaatgg tcgttatatc aagaacttcc tgctcaatcg tgctattttg
     7621 gatggtttcg gaagcaagct tatggttgga cgttttccac tggctgtcat tcacatccat
     7681 atcgaccctt atctagcgga tgtcaatgtg catccaacta agcaagaggt gcggatttcc
     7741 aaggaaaaag aactgatgac cctggtttca gaagctattg caaatagtct caaggaacaa
     7801 accttgattc cagatgcctt ggaaaatctt gccaaatcga ctgtgcgcaa tcgtgagaag
     7861 gtggagcaaa ctattctccc actcaaagaa aatacgctct actatgagaa aactgagccg
     7921 tcaagaccta gtcaaactga agtagctgat tatcaggtag aattgactga tgaagggcag
     7981 gatttgaccc tgtttgccaa ggaaaccttg gaccgattga ccaagccagc aaaactgcat
     8041 tttgcagaga gaaagcctgc taactacgac cagctagacc atccagagtt agatcttgct
     8101 agcatcgata aggcttatga caaactggag cgagaagaag catccagctt cccagagttg
     8161 gagtttttcg gacaaatgca cgggacttat ctctttgccc aagggcgaga tggactttac
     8221 atcatagatc agcacgctgc tcaggaacgg gtcaagtacg aggagtaccg tgaaagcatt
     8281 ggcaatgttg accagagcca gcagcaactc ctagtgccct atatctttga atttcctgcg
     8341 gatgatgccc tgcgtctcaa ggaaagaatg cctctcttag aggaagtggg cgtctttcta
     8401 gcagagtacg gagaaaatca atttattcta cgtgaacatc ctatttggat ggcagaagaa
     8461 gagattgaat caggcatcta tgagatgtgc gacatgctcc ttttgaccaa ggaagtttct
     8521 atcaagaaat accgagcaga gctggctatc atgatgtctt gcaagcgatc tatcaaggcc
     8581 aatcatcgta ttgatgatca ttcagctaga caactcctct atcagctttc tcaatgtgac
     8641 aatccctata actgtcctca cggacgtcct gttttggtgc attttaccaa gtcggatatg
     8701 gaaaagatgt tccgacgtat tcaggaaaat cacaccagtc tccgtgagtt ggggaaatat
     8761 taaaagtata aaaaagtctg ggaaaaattt tcaaaatcag aaaaacgcat aaaatcaggt
     8821 gttcaaaaac cttgatttta tgcgttttat catggaaata gttacttcat gttttcctaa
     8881 ttcttttcga aactcttttt aaaccacgtc agttttatca gtaatctcaa aacagtgttt
     8941 tgagctaatt ttgccagttt tatctgtaac atcgaagttg tgtttgacca ctctgcgact
     9001 ggtttcctag tttgctctat gattttcaca gagtattaaa ttgcgatttt gccaagtttc
     9061 tttattcgtc taaaagtaga gtctgttcta tgcgtctaat gtacgaatta ggttgaccat
     9121 ttcaatagct ccttgtgcac actcagaacc cttatttcct gctttggtac cagctcgttc
     9181 tatggcttgt tcaattgtat ctgtcgttag cacaccaaac ataacaggaa tttcgctatt
     9241 taaactgatt tgggcgattc ccttagatac ctcgctacat acataatcat aatgacttgt
     9301 attccctcta atgacagctc ccaagcagat aattgcatca tattttttac tttttgccat
     9361 ttttgatgca atcagtggta tttcaaaagc tcctggaacc caggctacct ctatatcttt
     9421 ctcgtttaca ttctctcttt tgagattatc tagtgctcca gataataatt ttgaagttat
     9481 aaattcatta aatctcgcta caacaatacc tattttaata ttgtttgcta ctaaattacc
     9541 ttcataagtg ttcatttatt tttcctccat atttaaaatg tgacccattc gatttttctt
     9601 tgtttctaaa taaaaactat cgtaaggatt ggcttctatt tcgattgata ttctactgga
     9661 aatggtaatt ccatattttt ctaactgttc aaccttgtca ggattatttg tcagtaaatg
     9721 aagtgactga agtcccagat ctttaagcat ttgtgctcca atatgatatt ctcttaaatc
     9781 accttcaaag cctaatgcaa gattggcatc aagcgtatcc atgccttgat cttgtaaatg
     9841 ataggctttt aatttattga taagtccaat tcctcgtccc tcctgtcgca agtaaagtaa
     9901 gacacccgaa ccattctcaa caatcatttt catagcttta tcgaattgct gtccacaatc
     9961 gcaacgtaaa gagcctaaaa catctcctgt taaacattcg gagtggaccc gacataatac
    10021 attggcttca tcctctatat ttcccataat aagagcaaga tgatgttccc catttagttt
    10081 atctatatag ctaattgctt tgaaattacc gtatctagta ggcatattga cagttgaaac
    10141 tcgttctacc agctgatcat atacttttct atattcttgt aattctttga tggtaattag
    10201 tggaatgttg tgtttcttcg agaactgaat taaatcatct gttctcatca ttttgccatc
    10261 atgattcatt atttcacaac ataggccaca ctcttttagt ccagctaatt ttaataaatc
    10321 aacagttgct tctgtgtgtc catttctttc tagaacacca cctttttttg caattaaagg
    10381 aaacatgtgt cctggcctgc gaaaatcaga gggtgttata tcttcagcta cacacatacg
    10441 tgcggtcagt cctctctcct cggcagaaat acctgtggtc gtttctttat aatcaattga
    10501 aactgtaaaa gcagtcttat gattatctgt attgttttca accataggtg aaagcattaa
    10561 ttgattagct aaactttcgc tcataggcat acaaattaat cctttggcat aagtagccat
    10621 aaaattaaca ttttctgttg tagctgcttg tgcagaacaa attaagtctc cttcattttc
    10681 tctatccttg tcgtctataa caagaacaag tcgtcccttc tgcaatgctt ctaatgcttc
    10741 ttgtattttt cgatattcca ttgactgatt atcctttctg ctaaaatcca ttttgatata
    10801 atagttcctt agatatttct gattttggag agttatccat cagtttttgc acatatttac
    10861 ctaagatatc attttcaaga tttactgtac tcccgacttg tttactctta agaatggttt
    10921 gttccaaggt atgagggata acagatactg aaaagtttac tttggagact ttagcgacag
    10981 tcagactaat gccgtcaatt gtaatagatc ctttttcaac tattaaatct aaaatttctt
    11041 tttgtgtgtt gatttgatac catacagcat tatcatcttt ttttattgac gagatttttc
    11101 ctgtaccatc aatgtgtcct gtaacgacgt gacccccaag tcgaccgttg acagataagg
    11161 ctctttctag attcacctca cttccatgtt ttaatagagt aagagctgtt cgactccatg
    11221 tttcattcat tacatcaact gtaaaggatt gatgattgaa atgagtaact gtaagacaga
    11281 taccatttac tgctatacta tcgcctaaat ggatatccgt taatattttt gaggctttaa
    11341 ttgatagttt acaattacga gagtctttct gtattctttc aacttttccg atttcttcaa
    11401 ttattcctgt gaacatggat aaatcacttc actttctatg agatagtcat ttcctatttg
    11461 agaaaaagca taaggtttca atctaatagc gtcatttggc aaagaaatgc cttcacctcc
    11521 gacaggaaac ttggcactgc ctccaaaaat ttttggtgca atatatattt tcagctcatc
    11581 aacaatttgt tgttccaaag cactccaatt cattagactg cccccttcta gaactaggct
    11641 atcaatctgc atgtttccta gatgttgcat taaactcgat aagtctatat gattgccttt
    11701 tttctttatg gaaagtattt cacagccatg attttgatat agcttcattt tatttttgtc
    11761 ttcagaggaa gtggcaatgt aagttttaat atcatttgct gtttttacga ttttagaggt
    11821 aagaggagtt cgtaaatgtg tatcgcatat gatacggata ggatttttcc cttcctccaa
    11881 tctacatgtc agcaaaggat cgtcttgaat aacagtattg actcccacca taattgcact
    11941 aacatggtgt cgtaactgat gcacatgctt tcttgcttct tcttcagtaa tccatttgga
    12001 ttgatttgtt ttagtggcta tttttccatc cattgacatt gcatatttca taaaaacata
    12061 gggtacatgc tgggtaatat actttctaaa actttttatt aagttaagac actcattttc
    12121 taaaattcca acagtaactt gaagattatt ttcctcaagt atctttactc cttttccaga
    12181 tacaatagga ttacagtcta ggcttccaat gactactctt gtaataccac tatcgattat
    12241 agcatctata cagggaggtg ttttcccgaa gtgacaacag ggttcaagtg ttacataaag
    12301 cgtcgctccg acaggggatt ctctacagtt tttaagagca tttctctcag catgtgggcc
    12361 accaaaaaac tcatgataac cttgtccgat gatgtgatta tcttttacaa taactgcgcc
    12421 gaccatagga ttgggattga cgtaaccagc ccctttttgt gccagtttta ttgctaattt
    12481 catatatttt gaatcgctca tctcactacc tccaaaaaaa atataccttg aataggggac
    12541 tactcaaggc atacaaaaga aaacttatgc gattaacaaa aatactctga aatgacaagt
    12601 aatcatttca gagcacgcaa aaagcacaaa tatactttta tcttctttca tccagactat
    12661 actgtcggct ttggaatttc accaaatcat gcctttcggc tcgtgggcta taccaccggt
    12721 agggaattac accctgccct gaagatagtt attcaattac agatgattat agtacttaat
    12781 tttgaatatg tcaacagata aataccgatt gtttttgata tactgtattt gtgataatcg
    12841 attctcgctc ctcggataaa gaaaatatga tatactagat aaacgaaata agagagaagg
    12901 aatactatgt acgcatattt aaaaggaatc attaccaaaa ttactgccaa atacattgtt
    12961 cttgaaacca atggtattgg ttatatcctg catgtggcca atccttatgc ctattcaggt
    13021 caggttaatc aggaggctca gatttatgtg catcaggttg tgcgtgagga cgcccatttg
    13081 ctttatggat ttcgctcaga ggatgagaaa aagctctttc ttagtctgat ttcggtctct
    13141 gggattggtc ctgtatcagc tcttgctatt atcgctgctg atgacaatgc tggcttggtt
    13201 caagccattg aaaccaagaa catcacctac ttgaccaagt tccctaaaat tggcaagaaa
    13261 acagcccagc agatggtgct ggacttggaa ggcaaggtag tagttgcagg agatggcctt
    13321 cctgccaagg tcgcagtgca agcaagtgct gaaaaccaag aattggaaga agctatggaa
    13381 gccatgttgg ctctgggcta caaggcaaca gagctcaaga aaatcaagaa attctttgaa
    13441 ggaacgacag atacagctga gaactatatc aagtcggccc ttaaaatgtt ggtcaaatag
    13501 gagcagagaa tgacaaaacg ttgttcgtgg gtcaagatga ccaacccact ctacatcgcc
    13561 tatcatgatg aggagtgggg ccagcccctc catgatgacc aagcgttgtt tgagttattg
    13621 tgtatggaaa cctatcaggc aggcctgtct tgggaaacgg tactcaacaa acgccaagct
    13681 ttccgagaag cctttcatag ctatcaaatt cactcagtcg cagagatgac tgacactgaa
    13741 ttggaagcca tgctggagaa tccagctatc attcgaaata gagccaagat ttttgctaca
    13801 cgcgctaacg cccaagcttt tctacagtta caggcagagt acggctcttt tgatgcctat
    13861 ctttggtctt ttgttgaggg gaaaactgtc gttaacgatg ttcctgatta tcgccaagcc
    13921 ccagctaaaa cacccttatc tgagaaatta gccaaagatc tcaaaaaacg agacttcaag
    13981 ttcacaggcc cagtcgccgt attgtctttt ctacaggctg cagggctagt tgatgaccac
    14041 gagaatgatt gtgagtggaa aggtcttaaa tgatgtctaa caaaaataag ggaattctga
    14101 tttttgcgat tctctataca gtcctctttg tgtttgatgg cgttaaattg ctggcttctt
    14161 taatgccatc tgccattgca aattatcttg tttatgtagt tttagctcta tatggctcct
    14221 tcttattcaa ggatagattg atccaacaat ggaaggagat tagaaagact aaaagaaaat
    14281 tcttctttgg cgtcttaaca ggatggctct ttctcattct gatgactgtt gtctttgaat
    14341 ttgtatcaga gatgttgaag cagtttgtgg ggctagtcgg acaaggtcta aatcagtcta
    14401 atattcaaag cacttttcaa gagcaaccac tactgatagc tgtttttgct tgtgtcattg
    14461 gacctctggt agaagaatta tttttccgtc aggtcttatt gcattacttg caggaacggt
    14521 tgccaggttt actaagcatt attctggtag gacttgtttt tgctctgact catatgcaca
    14581 gtttggctct atcagagtgg attggtgcag ttggttactt aggtggaggc cttgcctttt
    14641 ctattattta tgtgaaagaa aaagagaata tctactatcc actacttgtt cacatgttaa
    14701 gcaacagcct ctccttaatc attttagcta tcagtatagt aaaatgaaat aagaacagga
    14761 cagtcaaatc gatttctaac aatgttttag aagtagatgt gtactattct agtttcaatt
    14821 tgctgtaata tgtgatgaaa atgccagtaa tgataccgag aaaaaagctg agaaactttt
    14881 cccagcttta tttgttatag tcaaagcgaa tgacttgttc ctgtgcatct acatgagcat
    14941 ggaccccaaa gggtacaatt gctcttggag ttgcgtggcc ggcattcaga ttatagacaa
    15001 tcgggatatt gctgtcaatg atatccaata gtgcctcttt atagtcgtca tggaaagttt
    15061 catccatagg ttttccgacc aagagtccat tgatgaccgc gaatatgcca gtgtccttta
    15121 aagttagcaa catctttttg aagtcttctg gcttaggctt ttcttcgctt gtttcgagca
    15181 agaggatttt cccttcccag tctgacaagt cagggaaaag tttgtatttt tggcagagct
    15241 ccgtgctatc tgcgtatcga gagttgtcaa agatatcgta gagggattcg aggcaaccac
    15301 cgaggatttt cccctcgaat agtgcccttc cttgcaacaa gtcaaaacct gtatttgtat
    15361 gactgacacg aggtgttccc agggccgtgg gactaaaatc agttcgttcc tcataccaaa
    15421 cgtcactagg gcggatttct gaaattcttc ccgtctcaat caattcttta aagtagtgaa
    15481 ggctataggc tagcatttct ttgtctaatt cacaaatgtc tgctaaaaag gattgaccat
    15541 aaaaagtctt gattcctaat ttatgcaaca tgaggtggtt catggttgta tccgagaagc
    15601 caagaaaaat tttttgcttg ataacctttt ggagttggtc attttcaaaa agataaggta
    15661 gcaagcgata ggtatcgtct ccaccgatgg cacataggat catgtcgatg ctatcatcag
    15721 aaaaggcatg aatcaaatcc tctgcacgag cttcaggatg gtccttgata aagtctaatc
    15781 cttttaacga atggggcaaa aagatgggat tgagtcccag atccttgaga cgttggatac
    15841 ccaagtccac ttcgtgtttg acaaaatcct ctccgataat gccactagat aaactaacaa
    15901 taccaatagt agaaaccata tctcatcctc ctagaaatag attgagccta ttttatcaca
    15961 aaatataaga gaaagctatg tgggatttca gaagaatact tttaatactc ttcgaaaatc
    16021 tcttcaaacc acgtcagttt tatctgcaac ctcaaagctg tgctttgagc aacctgcagc
    16081 tagcttccta gtttgctctt tgattttcat tgagtataac tcaaaaaagt aagtgaaaaa
    16141 gcaaccgcac ctgcagttgc ttttatcgtt ttcttattct tgatagcgtg ttggtcctgc
    16201 acttgcacta cggatattca agcgtttctt gagatagaag cgaagggcta ggagggctgc
    16261 tccaataata gctagtggca atggatccag tactgggtta aggctagctg gtaggaagct
    16321 tgttgcaaag aagacaagca accaaaggaa cacagaagct aggataacta gtacagattt
    16381 ccagaaaggt ggacgttgac tgcgatccat atctggtcca tagtattggt aaacaaagta
    16441 gtacatcaag tagaaggcaa atccaccaac cagtccaact aatagaagag taatcaatcc
    16501 atagccgaaa gcttgatctg ccgcaaagaa ggttgtgagg gcgctgacaa gggcaaagag
    16561 gctagtgatg aaaagagctg agtccataat catcagtttt gggtcatcat tttcttttgg
    16621 atgctctttt tcgtactgct ctttgacagt gaagctatga gcccaatgag ttggtgcgcc
    16681 gtatagggaa cgggcagttg tacctttaga ttgctcctca aggatttggg gaatgacttc
    16741 ctcaaaaata gtctggattt cagcgtctgt tttcccatct ttgatgaatt gttgggtagc
    16801 aatgtggaca aactcttggt ttttcttagt taatttttgt agatcaattt gagacatagg
    16861 aactcctttt agaaccattt tttatggatg agatagagag tgagcgagac actcatagca
    16921 aaggcgataa agacgattaa ccagaaggca tttggctctc cgtttagggg aatttcatta
    16981 tccttaaagt tcatcccgta ggcagaaaag accatggttg ggatggacat gacgatggtc
    17041 acaagggcca aggttttcat gatgttgttc tggttgttag aaatgataga ggcaaaggtc
    17101 tctgtcatag aatgcaagac gtttccataa atatctgcca tctcgatggc ctgttgggtt
    17161 tcaatcaggg tgtcttcaag caggtcttcg tcctcaaggt atttcttgat attgctggtt
    17221 gaactggtca atttcttaat cacgcgctca tttgttttga gggaggcctt gaaatagacg
    17281 atagtttttt ccaattccat gagctcaatc aattcttcat tacgagttga ttgatgcagt
    17341 tgactttcga tttgttcact cttgcggtcg attgaacgaa gggctgttag gtaaagctct
    17401 gcattgcgat aaagaatttg aaagataaaa cgtgaacgca tgaaggtata gaaattacgc
    17461 aatcgacggt tgataaagac atcaaggaca ggtagtggtt ccaaacacgt agtgataatg
    17521 gtttcctcag tgatgataat accaagcggg atggttacgt agtaggtgcg gttatttctt
    17581 tcctccgtga ccggcacgtc tacgataatc agggtatact cgtcttcaat ggtaatacga
    17641 gacatttctt ccgcatcgag cggtgctcga aggtcggcaa tatcaatatc gaaggtgttg
    17701 gcgatttcga gtgattcatt ttgagtcgga ttgacgagat tgatccaagt acccggttca
    17761 agcgtatcga tctctttaaa ttcagttgtt gtagagagaa aaacttgttt catatccctt
    17821 atcctttctc atttttcaga ttttttcaca ctgtactatt atactacaaa atcggccttt
    17881 tgggtaatag aatctcactt tttttggtat aatggtaagc aataatggac tagaaagaac
    17941 aaagatgcaa gataaaattg tcattcatgg ggcgcgtgcc cataatttaa aaaatattga
    18001 tgtggagatt ccgcgagaca agttggttgt cgtgactggc ttgtcaggtt cagggaagtc
    18061 cagtttggct tttgataccc tctatgcgga gggacaacgt cgctatgtag agagtttgtc
    18121 cgcctacgct cgtcagttct tgggaaatat ggaaaaacca gatgtagatg ccattgatgg
    18181 tctcagccca gctatttcta tcgaccagaa aacgactagc aaaaaccctc gctcgacggt
    18241 gggaacaacg actgaaatca atgactatct gcgtctcctc tacgcgcgtg tggggacgcc
    18301 ttactgtatc aacgggcatg gggctatcaa ggcttcttct gtggagcaaa tcgttgataa
    18361 ggttttggag ttacctgaac gccagcgctt gcagatcttg tctcctgtca tccgcaagaa
    18421 aaaaggccaa cataagagtg ttatcgagaa ggttcagaaa gacgggtatg ttcgtgtccg
    18481 tgtggatggg gaagtctatg atgtgaccga agtgccagag ttgtctaaga gcaagcaaca
    18541 caatatcgat gtcgtggttg accgtattgt tatcaaggag ggcattcgta gtcgtctctt
    18601 tgattccatt gaggctgccc ttcgtattgc agaaggttat gtcattatcg acaccatgga
    18661 caactctgag ttgttgttct ctgagcatta tgcctgtcca gtttgtggtt ttactgtccc
    18721 agagttagag cctcgtctct tttctttcaa tgctcctttt ggctcttgta gtgagtgtga
    18781 cggcttgggc atcaagctgg aggtggatac tgatttggta gtgccaaatg ccagcaaaac
    18841 cttacatgag ggagcgctgg caccttggaa tcctatctca tccaactact atccaaacat
    18901 gctagagcag gccatgacgg cttttggagt ggctatggat aagccttttg aggacttgtc
    18961 agaagaagac aagaacttga ttctctacgg ctcagatggt aagaaattcc atttccacta
    19021 tgagaatgaa tttggtggcg tgcgcgatat cgacattccg tttgagggag ttatcaataa
    19081 tatcaaacgt cgttaccatg aaaccaatag cgattacact cgcactcaga tgcgcctcta
    19141 catgaatgag ctgacttgcg gaacctgtca cggttatcgt ctcaatgacc aggccttgtc
    19201 tgtccgtgtg ggtggtgagc aagggccaca tatcggagaa atttcagacc tgtctatcgc
    19261 agatcacttg gacttggtga gccagttaac tttgtctgaa aatgaagcca tcattgctcg
    19321 tcccattctc aaggaaatca aggatcgttt gaccttcctt aataatgtgg gtcttaacta
    19381 tctaaccctg tcacgttcag caggaaccct ttcaggtggg gaaagtcagc gcattcgttt
    19441 ggcaacccag attggttcca acctatcagg cgtcctctat atcctagacg agccgtcaat
    19501 cggtcttcac cagagagaca atgaccgcct gattgccagt ctgaaaaaga tgcgtgactt
    19561 gggcaatact cttatcgtgg tggaacacga cgaagatacc atgcgtgaag ctgattatct
    19621 gattgacgtt ggtcctggtg ccggtgtttt tggtggtgag attgttgcag caggtacacc
    19681 taagcaagtg gctcgcaaca gcaagtctat cacaggtcag tacttgtcag gcaaacgtgt
    19741 catcccagta ccagaagagc gccgtgtcgg aaatggtcgt tttattgaag tgataggagc
    19801 gcgtgagaac aacttgcaaa atgtcacggc tcgctttcca ctaggaaaat ttatcgcagt
    19861 gacaggtgtg tcgggttcag ggaaatcgac tctaatcaac agcattctca aaaaagccat
    19921 tgcccagaag ctcaaccgta attcagacaa acctggtaag tttaagacta ttacagggat
    19981 tgagcatgtc gaccgtttga ttgatattga ccagagccct atcggacgga cgccgaggtc
    20041 taacccagct acctatacag gagtttttga cgatatacgt gacctttttg ctcagacaaa
    20101 tgaagccaag attcgaggct acaagaaggg acgcttcagt ttcaacgtca agggaggtcg
    20161 ctgtgaagct tgctcaggtg acgggattat caagattgag atgcacttct tgccagatgt
    20221 ttatgtggct tgtgaagttt gccacggaac ccgctataac agtgaaaccc tagaagttca
    20281 ctacaaggaa aagaatattt cgcaggtctt ggatatgacg gtcaacgatg cggtagaatt
    20341 tttccaacac attccgaaaa ttcaacgcaa actccagacc atcaaggatg tagggctagg
    20401 ctatgtgacc ttgggacagc cagctaccac cctttctggg ggagaagccc aacgtatgaa
    20461 gttagctagc gaactccaca aacgctcgac aggaaaatct ttctacattc tggatgaacc
    20521 gacgacaggg cttcatacag aggacattgc tcgcctgctc aaggttttag ctcgctttgt
    20581 agacgatggc aatacagtcc tcgtcatcga gcacaatctg gatgttatca agacggcaga
    20641 ccatatcatt gacttgggac ctgagggcgg tgtcggtggt ggaaccatca tcgtaacagg
    20701 aactccagaa gaagtagctg ccaacgaagc cagctataca ggacactatt tgaaaggaaa
    20761 gttacatcat gaataaacgc gtacaagcat ttctagctaa aatgcaagaa aaagaactag
    20821 atggtgtcat catcaacaat cttaaaaacg tctattattt gactggtttt tggggctcaa
    20881 acggaacagt ctttatcagc cgtgaccgtc aggtattagt gacagactct cgctatatca
    20941 tcgcagctaa gcaagaaacc agtggttttg agattgtggc tgatcgtgat gaattggctg
    21001 tcattgcagg aattgttaag gacatgggct tgactcgtat cggttttgaa gatgagattt
    21061 cagtgtctta ttaccaccgt atgcaggcag cttttgcagg tttgaacttg cttccacaaa
    21121 ctcagtttgt ggaaggtctt cgtatgatta aggatgaggc agagattgca gcgattcgca
    21181 aggcttgttc tatctcagac caagctttcc gcgatgcgct tgactttatc aaaccaggaa
    21241 aaactgaaat tgagattgcc aacttccttg atttccgcat gcgtgagttg ggagcatctg
    21301 gcttatcttt tgatacgatc ctagctagcg gtatcaattc ttctaaaccc catgcccatc
    21361 caatgcacaa accagtggag ttgggagaag ccattaccat ggacttcggc tgtctctatg
    21421 accactatgt cagtgatatg acccggacta tctatctagg gcatgttagc gatgagcagg
    21481 cagagattta caatacggtt ctaaaagcta accaagcctt gattgaccaa gctaaggcag
    21541 gcttaggttt ccgtgacttt gacaaaatcc ctcgtgatat tatcattgag gcaggttatg
    21601 gtgactactt tactcacggc attggccacg gtattggtct ggatatccat gaggaaccct
    21661 actttagtca gacttctaca gaaactatta agacaggtat ggccttgacc gatgaaccag
    21721 gtatctatat cgaaggcaaa tatggcgttc gtatcgagga tgatatcctg attacagaga
    21781 caggttgtga attattgacc ctagctccaa aagagttgat agtcatttag ttgtttgtca
    21841 agaaaaaagt acgaaaatga cgaaaaaagt caaaaaaaat t
//
LOCUS       DAVAZT010000038        21414 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVAZT010000038 DAVAZT010000000
VERSION     DAVAZT010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21414
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.038"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            66..287
                     /locus_tag="VQT45_001370"
     CDS             66..287
                     /locus_tag="VQT45_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2359687.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLELTDFPDKIRFRK"
     gene            804..1043
                     /locus_tag="VQT45_001371"
                     /pseudo
     CDS             804..1043
                     /locus_tag="VQT45_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            1187..2416
                     /locus_tag="VQT45_001372"
     CDS             1187..2416
                     /locus_tag="VQT45_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET2359688.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            2436..5132
                     /gene="ppc"
                     /locus_tag="VQT45_001373"
     CDS             2436..5132
                     /gene="ppc"
                     /locus_tag="VQT45_001373"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HET2359689.1"
                     /translation="MSLQKLENSSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATNLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYEIILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    5215..5432
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5545..6549
                     /locus_tag="VQT45_001374"
     CDS             5545..6549
                     /locus_tag="VQT45_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2359690.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     IELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTIKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            6618..7484
                     /locus_tag="VQT45_001375"
     CDS             6618..7484
                     /locus_tag="VQT45_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2359691.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            7481..8239
                     /locus_tag="VQT45_001376"
     CDS             7481..8239
                     /locus_tag="VQT45_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2359692.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            8329..10089
                     /gene="dnaG"
                     /locus_tag="VQT45_001377"
     CDS             8329..10089
                     /gene="dnaG"
                     /locus_tag="VQT45_001377"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HET2359693.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKTSEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            10092..11201
                     /gene="rpoD"
                     /locus_tag="VQT45_001378"
     CDS             10092..11201
                     /gene="rpoD"
                     /locus_tag="VQT45_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HET2359694.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            11215..11544
                     /locus_tag="VQT45_001379"
     CDS             11215..11544
                     /locus_tag="VQT45_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET2359695.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            11659..12702
                     /gene="cpoA"
                     /locus_tag="VQT45_001380"
     CDS             11659..12702
                     /gene="cpoA"
                     /locus_tag="VQT45_001380"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HET2359696.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAVLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            12718..14043
                     /locus_tag="VQT45_001381"
     CDS             12718..14043
                     /locus_tag="VQT45_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET2359697.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGILIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGALYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFRTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            14074..14250
                     /locus_tag="VQT45_001382"
     CDS             14074..14250
                     /locus_tag="VQT45_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET2359698.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            14309..14443
                     /locus_tag="VQT45_001383"
     CDS             14309..14443
                     /locus_tag="VQT45_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HET2359699.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            14507..15817
                     /gene="obgE"
                     /locus_tag="VQT45_001384"
     CDS             14507..15817
                     /gene="obgE"
                     /locus_tag="VQT45_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HET2359700.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            15827..15985
                     /locus_tag="VQT45_001385"
     CDS             15827..15985
                     /locus_tag="VQT45_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359701.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            17035..18294
                     /locus_tag="VQT45_001386"
     CDS             17035..18294
                     /locus_tag="VQT45_001386"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET2359702.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            18310..18861
                     /locus_tag="VQT45_001387"
     CDS             18310..18861
                     /locus_tag="VQT45_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2359703.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            18854..20131
                     /locus_tag="VQT45_001388"
     CDS             18854..20131
                     /locus_tag="VQT45_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET2359704.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIDRLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            20147..21007
                     /locus_tag="VQT45_001389"
     CDS             20147..21007
                     /locus_tag="VQT45_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HET2359705.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
BASE COUNT         6551 a         3678 c         4805 g         6380 t
ORIGIN      
        1 ccagttagga cactttgaat gatttcttag ttttatatat tatacttttc tcaggagaaa
       61 gctagatgta cagacgtttg agagatttga gggaagatca cgatttgacc caaaaacaaa
      121 tagctaaaat actttcgttt acaaactcag cttatgctaa aattgaacgg ggtgagcata
      181 cgttaacagc agatgtattg gtaactctct caaactttta cgatgtcagt acagactacc
      241 tattggaatt gacagatttt cctgataaaa ttcgctttag aaaataatct cctcaatttc
      301 atagagtgtg aaaatgagga gattttttat ttgttctttg aaaattaaat agtccaaaat
      361 ggtactttcc tcatttgtgg agcaaatttg aatggctcgc catgataaga gcgattttaa
      421 agccatcaat aaaatagagc gatactttat atgccatgat acaaatgata tacaatgata
      481 cttctgaccg ttcaggctgc catcgtaaaa gagcagcaag tgaaattctt atgatgactt
      541 catcagtcat gccacgttga atgtgtgagt ttgttagaga aacgcaatta atcctcaaaa
      601 ggttccccga accttttgag ttccacagac gcatcacgtg gagtgtgtaa gcttgttgct
      661 aaaagcgtaa aaaccttgga acgaaaggaa taatagactt cctgcgaaac aaaaatacaa
      721 tacaataaaa ctatggatga tgaagcaagt aaacaattaa gcgatagccg tttcaagagc
      781 cttgtaggtg ttcagcgcac gagatgttag ctgtgttaaa aacagcttat caacgcaacg
      841 taaacgcgca aaaggtggac gaaaaaccaa attaagccta gacgatctcc tcatggtaac
      901 tattcaatac atgcgagaat agcgcactta tgaacaaatt gcggctgatt ttggcattca
      961 cgaaagcaac ataattagtc ggaggtcaat ggattgaagc aactcttatt caaaatggtt
     1021 ttacgatttc aaattctgcc ttaattctgt aaaaacagta aaattcgaag gattgtaagg
     1081 taagagtttt tttctttctg aaaaaatggt ataatagcaa tcaaaactag aaaataaaac
     1141 ggaatttgga acagatttgt ctgtatccta gtagagtggt gatactatga agattagtaa
     1201 gaggcactta ttaaattatt ccatcttgat tccctacttg cttttatcta ttttgggctt
     1261 gattgtggtc tattcgacca ccagtgctat tttaattgaa gaaggcaaga gcgccttgca
     1321 gttggttcga aaccaaggaa tcttttggat tgttagtttg atactgattg ccttaattta
     1381 taaattgaga ctagattttt tgagaaatga gcgactaatc attttagtta tattaataga
     1441 aatgctttta ttgttcttgg ctcgttttat tggtatttca gtaaacgggg catacggttg
     1501 gatttcggtt gcaggagtaa ctattcagcc agctgagtac ttaaaaatca ttattatttg
     1561 gtatttagct caccgattct ccaaacagca agaagaaata gctacttatg attttcaagt
     1621 tttgactcaa aatcaatggc ttccccgtgc ttttaatgat tggcgattcg ttctcctagt
     1681 tctgattgga agtttgggaa ttttccctga tttaggaaat gcgactattt tagtcttggt
     1741 ttccttgatt atgtatacag ttagtggaat cgcttatcgc tggttttcaa ccattctggc
     1801 gctcgtatct gccgcttctg tctttgtctt gaccactatc agcctaatcg gtgttgagac
     1861 cttttcaaaa attccagtat ttggctatgt agccaaacgc tttagtgcct tttttaatcc
     1921 ttttgccgat cgtgctgatg caggtcacca gttagctaat tcttattttg ccatggtcaa
     1981 tggtggttgg tttggtctag gtcttggaaa ctcgattgaa aaacgaggtt atttgccaga
     2041 agctcataca gactttgtct tttctatcgt gattgaagaa tttggctttg ttggtgccag
     2101 tcttatttta gctctcttgt ttttcatgat tttgcggatt atcttggtcg gtattcgagc
     2161 ggagaatcct ttcaatgcca tggttgcact cggtgtcgga gggatgatgt tggttcaggt
     2221 atttgtcaat atcggaggga tttcgggctt gattccatct acaggagtaa ccttcccctt
     2281 cttatcccag ggtggaaata gtcttctagt cttatcagtg gcagtagcct ttgtcttaaa
     2341 tattgatgcc agtgaaaaac gcgctaagtt gtaccgagaa ttggaaaatc aaccaatgaa
     2401 ccttctgttg aagtaggata aagaaaggat agtttatgtc tcttcaaaaa ttagaaaatt
     2461 ctagtaataa aagtgttgtg caagaagaag tcttgattct aacagaatta ctggaagata
     2521 ttactaaaaa tatgcttgcc ccagagacct ttgaaaaaat aatacagttg aaagaattat
     2581 caacgcagga agattatcaa ggtctaaacc gtctagtgac tagcttatca aatgatgaaa
     2641 tggtctatat ttcacgctat ttctctatct tgcctctttt gattaatatt tcagaggatg
     2701 tggatttagc ttatgaaatc aatcatcaaa ataatattga tcaggactat ttaggtaaat
     2761 tatctacaac gattaaattg gtagcagaaa aggaaaatgc cgttgagatc ctagaacact
     2821 tgaatgttgt tccggttttg acagcccatc caacacaagt gcaacgcaaa agtatgttgg
     2881 atttaacaaa tcatattcat agtcttttgc gtaaataccg tgatgttaag ttggggttga
     2941 tcaataaaga taaatggtac aatgatttgc gtcgttacat cgaaattatc atgcagacag
     3001 acatgattcg tgagaaaaaa ttaaaagtga ctaacgaaat cacgaatgct atggaatatt
     3061 ataacagctc ctttttgaaa gctgtacctc atttgacgac ggagtataag cgcttagcgc
     3121 aagcgcatgg tctgaattta aaacaggcta aaccaatcac catgggtatg tggataggtg
     3181 gtgaccgtga tggaaatcca tttgttacag caaagacctt gaagcagtct gcactcactc
     3241 aatgtgaagt catcatgaac tactatgata aaaagattta ccaactttat cgtgaatttt
     3301 ctctttcaac tagcattgtc aacgtcagca agcaagtcag agaaatggct cgtcaatcca
     3361 aggataactc gatttaccgc gaaaaagagc tttaccgtcg tgccttgttt gatattcaat
     3421 caaaaattca ggcaactaaa acctatctga ttgaggatga agaagttggg actcgttatg
     3481 aaaccgccaa tgatttctac aaggatttga ttgccattcg agattctcta ctagagaata
     3541 agggcgagtc cttgatttca ggtgattttg tggaattatt gcaggcagta gagatatttg
     3601 gtttttacct agcatcaatt gatatgcgac aagactctag cgtctatgaa gcctgtgtgg
     3661 cagaactctt gaaatcagca ggaattcatt ctcgttatag cgagttgagc gaagaagaaa
     3721 agtgtgacct tcttttgaaa gaattagaag aagatccccg aattctttct gcgactcacg
     3781 cagaaaaatc agaattatta gcaaaagaac tagctatttt taagacggct cgtgttttga
     3841 aagataagtt gggagatgat gtcatccgtc agaccatcat ttcacatgca accaaccttt
     3901 ctgatatgct agaattagct attctgttaa aagaagtagg actggtggat acggaaaggg
     3961 cgcgtgttca gattgttccc ctttttgaaa caattgaaga cttggatcat tcagaggaaa
     4021 caatgagaaa atatctttct cttagccttg ccaaaaaatg gattgactca cgaaataact
     4081 accaagaaat catgcttggc tactctgaca gtaataaaga tggcggttac ttgtcatcat
     4141 gttggaccct ctacaaggct caacaacaat tgactgctat tggagatgaa tttggcgtta
     4201 aggttacctt cttccatggt cgtggtggta ctgtcggtcg tggtggtggg ccaacctatg
     4261 aagccattac atctcaaccg ctcaagtcta tcaaggatcg tatccgtttg acggagcagg
     4321 gtgaagtaat tgggaataaa tacggtaaca aagacgccgc ttactataac cttgaaatgc
     4381 tagtatcggc agctattaac cgtatgatta ctcagaagaa gagcgatacc aataccccaa
     4441 atcgttatga agccattatg gatcaagtag tggaccgtag ttacgatatc taccgtgatt
     4501 tggtctttgg taatgagcat ttctatgatt atttcttcga gtcaagtcca atcaaggcta
     4561 tttcaagttt taatattggt tctcgtccag ccgctcgtaa gactattact gaaatcggtg
     4621 gtttgcgtgc catcccttgg gtattctcat ggtcacagag tcgtgttatg ttccctggat
     4681 ggtacggggt tggttcaagc ttcaaggaat ttatcaataa aaatccagag aatattgcta
     4741 tcttacgaga tatgtaccaa aattggcctt tcttccaatc gcttctttca aatgttgata
     4801 tggttttgtc aaaatcaaat atgaatattg cttttgaata tgctaaactt tgtgaagacg
     4861 agcaagttaa ggccatctat gagattattt taaatgaatg gcaagttact aagaacgtta
     4921 tcttggctat tgaaggacat gacgaactct tagctgacaa tccatatcta aaagctagtc
     4981 tggattaccg tatgccttac tttaatattc tcaactatat tcagttagag ttgattaaac
     5041 gccaacgtcg tggagaattg tccagtgatc aagaacgatt gattcatatc accatcaacg
     5101 gaattgcgac aggattgcgt aattcaggtt gataattttc aagagtgaat gctaaaagtg
     5161 aatatcaaaa aaattctaat agactattga caagtagttt aaaaatgata taatttaacc
     5221 attcagaaaa gtaatcatac aaacttttta gagagtctgt ggtagctgaa aacagataag
     5281 tggcgatgat gaaaattggg ctgaatgcta tttagaattt gaaattataa aaattcggta
     5341 agcacacctt acagtgcatc tcgttattgc gagactgagc gatagggaaa ttccctataa
     5401 ttgaggtggt accgcgcatc gacgtcctca cacaagtttt ttgtgtgagg atttttttga
     5461 tggaggttag tatggaaaga aaacgatggc gtcgcttgtt tagataagtg aaatatgtta
     5521 aaggaaataa aaaggagaaa cagaatgaaa aataaacgtt taattggaat tattgctgca
     5581 ttagcagtct tagtagcagg aagcttgatt tattcttcaa tgaataaatc agaagctcag
     5641 aataataagg atgagaagaa aataaccaag attggtgtgc ttcaatttgt gagccatcca
     5701 tcccttgatt tgatttataa agggatccaa gatggacttg cagaagaagg atataaagat
     5761 gatcaagtta aaattgattt tatgaactca gaaggtgatc aaagtaaggt tgcgacaatg
     5821 agtaaacaat tggttgcaaa tgggaatgac cttgtggttg gtattgcaac accagcagcc
     5881 caagggttgg ctagtgcaac aaaagaccta ccagttatca tggccgctat tacagaccca
     5941 attggtgcta acttggttaa agatttgaaa aaaccaggtg gtaacgttac aggggtatct
     6001 gaccacaatc cagctcaaca acaaattgaa ctcatcaagg ctctgacacc gaatgtgaaa
     6061 acaatcggag ctctttactc aagtagcgaa gacaattcaa aaacacaggt tgaagaattt
     6121 aaggcttatg ctgaaaaagc aggtctgaca gtggaaacat ttgcagttcc ttcaacaaat
     6181 gaaattgcct caactgtcac tgttatgact atcaaggtag atgctatttg ggttccaatt
     6241 gataacacca ttgcatcagg atttccaacg gttgtctcta gcaatcaaag ttctaagaaa
     6301 ccaatttatc ccagtgcgac agctatggta gaagtaggtg gtttggcatc agttgtaatt
     6361 gaccaacatg accttggtgt ggcaacaggt aaaatgattg tgcaagtctt gaaaggtgca
     6421 aaaccagccg ataccccagt caatgtcttt tcaactggta agtcagtcat caataaaaaa
     6481 atagcacaag aactaggtat tactattcct gagtctgttc tcaaagaagc aggacaagtc
     6541 atcgaataaa taaggtaggg aggaggagac tcttcccatt ttttaaaaag atgaatatag
     6601 aaaggattaa ataaaatatg attgtttcca ttatttctca aggatttgtc tgggctattc
     6661 taggtctggg aatctttatg acatttagga ttttaaactt tccagatatg acgacagaag
     6721 gttccttccc tcttggggga gctgttgctg tcactttgat aaccaaaggc gtgaacccat
     6781 ttttagcgac acttgttgct gtaggagcag gttgtttggc tggaatggca gcaggccttc
     6841 tttatacaaa agggaagatc ccaaccttgc tctcagggat tttggtgatg acttcttgtc
     6901 actcaatcat gctcttgatt atgggacgtg cgaatttagg cctgcttgga accaagcaaa
     6961 ttcaggatgt tttgcctttt gattcggatt tgaatcaact cttgacaggt ctcatctttg
     7021 tgagcattgt tattgctctc atgctctttt tcttggacac taaactcgga caagcctata
     7081 ttgctacagg ggataatcct gatatggcta gaagtttcgg gattcatact ggacgcatgg
     7141 agctcatggg cttggtctta tcaaatggtg tgattgccct tgcaggtgcc ctcattgctc
     7201 agcaagaagg ctatgccgat gtgtctcgag ggatcggggt tatcgttgtg gggcttgcaa
     7261 gtttgattat tggagaagtt attttcaaga gtttgagctt ggcagagcgt ttggttacta
     7321 tcgttgtagg ttctatcgct tatcaatttt tagtgtgggc agttatcgca cttggcttta
     7381 atacaagtta ccttcgttta tacagtgcct tgattttagc agtctgcctc atgattccaa
     7441 catttaagca aacaatcttg aaaggagcca agttaagcaa atgacagcaa ttgtagaatt
     7501 aaaaaatgca accaaaattg ttaaaaatgg ctttgatgaa gaaaagatta ttttaaatga
     7561 tgtttcctta gaaatttttg aacgggactt tatcacgatt ttgggcggaa atggtgctgg
     7621 aaaatcaacc ctctttaaca ctatagcagg gaccttatca ctaactagtg gaactatccg
     7681 tattttaggt gaagatctca ctaagttttc acccgagaag cgtgccaagt acctgtctcg
     7741 tgtcttccaa gatccaaaga tggggacagc tccccgtatg acggtcgctg aaaatctttt
     7801 aatcgccaag tttcgtggtg agaagcgtgg attgttacca cgacgcttga ctagctataa
     7861 ggatgaattt caggcaacca ttgaaaaagt aggaaatggt cttgagaaac acttgaatac
     7921 accgattgag ttcttatcag gtggacaaag acaggctttg agtctcttga tggcaacctt
     7981 gaagcgacct gaattactcc tgttagatga gcatactgct gccctggatc caaagactag
     8041 tgttgctttg atggaattga cagatgaatt tgttaagaaa gatcagctaa cagcccttat
     8101 gattactcat catatggaag atgctctcaa atacggcaat cgcttgattg tcatgaaaga
     8161 aggacggatt atccaagatt taaaccaaga agaaaaagca aaaatgaaaa tctctgatta
     8221 ttatcaactc tttgaataaa gtagggaaaa tgagtgaaat ggtttacttt ttttctgaaa
     8281 taaagtatac tatataaagt aaactatgat aacatggagg tattgtgtat ggttgacaaa
     8341 caagtcattg aagaaatcaa aaacaatgcc aacattgtgg aagtcatagg agatgtgatt
     8401 tctttacaaa aggcaggacg gaactatcta gggctctgtc cttttcatgg tgaaaaaaca
     8461 ccttctttca acgttgtaga ggacaagcag ttttaccact gttttggttg tggtcgctca
     8521 ggtgatgtct ttaaattcat cgaggagtac caaggggtta cctttatgga ggctgtccaa
     8581 atcttaggtc agcgtgtcgg gattgaggtt gaaaaaccgc tttatagtga acagaagcca
     8641 gcctcgcctc accaagctct ttatgatatg cacgaagatg cggctaaatt ttaccatgct
     8701 attctcatga caacgactat gggcgaagag gccagaaatt acctttatca gcggggtttg
     8761 acagatgaag tgcttaaaca tttttggatt ggtttagcac ctccagaacg aaactatctc
     8821 tatcaacgtt tgtctgatca gtatcgtgaa gaggatttac tggattcagg cctgttttat
     8881 ctctcggatg ccaatcaatt tgtagacacc tttcacaatc gcattatgtt tcccctgaca
     8941 aatgaccaag gaaaggtcat tgccttctca ggtcgtatct ggcaaaaaac ggattcacaa
     9001 acttctaagt ataaaaacag ccgatcgact gcaattttta acaaaagtta cgaattatat
     9061 catatggata gggcaaaaaa atcttctgga aaaactagtg agatttacct gatggaagga
     9121 ttcatggatg ttattgcagc ctatcgggct ggaatcgaaa atgctgtggc gtcgatggga
     9181 acggccttga gtcgagagca tgttgagcat ctgaaaaggt taaccaagaa attggttctt
     9241 gtttacgatg gagataaggc tgggcaagcc gcgatattga aagcattgga tgaaattggt
     9301 gatatgcctg tgcaaatcgt tagcatgcct gataacttgg atcctgatga gtatctacaa
     9361 aaaaatggtc cagaagactt ggcctatcta ttaacaaaaa ctcgtattag tccgattgag
     9421 ttctacattc atcagtacaa acctgaaaac agtgaaaatc tgcaggctca gattgagttt
     9481 attgaaaaaa tagctccctt gattgttcaa gaaaagtcca tcgctgctca aaacagctat
     9541 attcatattt tagctgacag tctggcgtcc tttgattata cccagattga gcagattgtt
     9601 aatgagagtc gtcaggtgca aaggcagaat cgcatggaaa gaatttccag accgacgcca
     9661 atcaccatgc ctgtcaccaa gcagttatcg gctattatga gggcagaagc ccatctactc
     9721 tatcggatga tggaatcccc tcttgttttg aacgattacc gtttgcgaga agactttgca
     9781 tttgctacac ctgaatttca ggtcttatat gacttgcttg gccagtatgg aaatcttcct
     9841 ccagaagttt tagcagagca gacagaggaa gttgaaagag cttggtacca agttttagct
     9901 caggatttgc ctgctgagat atcgccgcag gaacttagtg aagtagagat gactcgaaac
     9961 aaggctctct tgaatcagga caatatgaga atcaaaaaga aggtgcagga agctagccat
    10021 gtaggagata cagatacagc cctagaagaa ttggaacgtt taatttccca aaagagaaga
    10081 atggagtaat aatggcaaca aaacaaaaag aagtaacaac atttgacgta caggtagcag
    10141 aatttatccg taatcataag caaaaaggga cagcaacaga tgatgaaatc aatgcaagtc
    10201 tggttattcc ttttaccttg gacgctgatg ggattgaaga tctcttgcaa cggattcagg
    10261 atgcagggat ttctatcaca gataacgaag gaaatccaag tgcgcgtgtt cttagcaatg
    10321 aagaagaacc agaactcagc gatgaggact tgattggatc aacttctgct aaggtcaatg
    10381 accctgtccg tatgtacttg aaagaaatag gggtcgttcc tctcttgacc aatgaagagg
    10441 agaaagagtt ggcactggct gttgaagctg gcgatatcga agccaaacaa cgtcttgcgg
    10501 aagccaatct tcgtttggtt gtttccattg ccaaacgcta tgtcggtcgt ggcatgcagt
    10561 tccttgactt gattcaagaa ggaaatatgg gcttgatgaa ggcggttgac aagtttgact
    10621 attctaaagg gttcaagttt tcaacttatg caacttggtg gattcgtcag gctatcactc
    10681 gtgctattgc ggaccaagct cgtaccatcc gtatcccagt tcacatggtt gaaactatca
    10741 ataaattggt tcgtgaacag cggaatctcc ttcaagaatt ggggcaagat ccgacaccag
    10801 aacagattgc tgaacgaatg gatatgacac ctgataaggt tcgtgaaatc ttgaagattg
    10861 cccaagaacc agtatctctt gaaactccta tcggtgaaga ggacgatagc caccttggag
    10921 actttatcga agatgaagtg attgaaaatc cagtggatta tacgactcgt atcgtcttgc
    10981 gtgagcaatt ggatgaaatc ttagatactc ttacagaccg tgaagaaaat gttctgcgtc
    11041 tacgttttgg actagatgat ggaaaaatgc gcacacttga agatgtgggg aaagtcttta
    11101 acgtaactcg tgagcgtatc cgtcagattg aagcaaaggc tttgagaaaa ctacgccaac
    11161 caagtcgcag caaaccgctt cgtgatttta ttgaagacta agagtgagga aaatatggct
    11221 tatacagaag agcaaattga aaacatcaaa acacggattt taacagcctt ggaagaagtc
    11281 atcgaccctg agttgggaat cgatattgtc aatcttggtt tgatctatga gattcgtttt
    11341 gacggtgaca cagggcaaac agagattgac atgactttga caactatggg ttgtccctta
    11401 gcagaccttt tgacagacca gatttatgat gctatgatag aggttccaga agtaacggat
    11461 actgaggtta aattagtctg gtatccagcc tggacagttg aaaaaatgag tcgctatgcc
    11521 cgcattgccc taggcattaa gtaaacatat aaaagcatgt gagagactag aggaaaagcg
    11581 aggaaatttc ccctcttttc ctctagtctc tcctttcttt tgctgatttt attcaaagaa
    11641 aatgatataa tagtagttat ggagaaaaag aaattacgca tcaatatgtt gagttcaagt
    11701 gagaaagtag caggacaggg agtttcaggt gcttaccgtg aattagttcg tcttcttcac
    11761 cgtgctgcca aggaccaatt gattgttaca gaaaatcttc caatcgaggc agatgtgact
    11821 cactttcata cgattgattt tccctattat ttatcaacct tccaaaagaa acgctcaggg
    11881 agaaagattg gctatgtgca tttcttgcca gctacacttg aaggaagttt gaaaattcca
    11941 tttttcttaa agggaattgt gaaacgctat gtattttctt tttacaaccg gatggagcac
    12001 ttggttgtgg tcaatcctat gtttattgag gatttggtag cagctggtat tccacgtgaa
    12061 aaagtgacct atattcctaa ctttgtcaac aaggaaaaat ggcatcctct accacaagaa
    12121 gaggtagtca gactgcgcac agatcttggt cttagtgaca atcagtttat cgtagtaggt
    12181 gctgggcaag ttcagaaacg taaagggatt gatgacttta tccgtctggc tgaggaattg
    12241 cctcagatta cctttatctg ggctggtggc ttctcttttg gtggtatgac agatggttat
    12301 gaacactata agaaaattat ggaaaatccc cctaaaaatt tgatttttcc aggcattgta
    12361 tcgccagagc ggatgcgcga attgtatgct ctagcggatc ttttcttgtt gcctagttac
    12421 aatgagctct ttcctatgac tattttagaa gctgcgagtt gtgaggctcc tattatgttg
    12481 cgtgatttag atctctataa ggtgattttg gagggaaatt atcgggcgac agcgggtaga
    12541 gaagagatga aagaggctat tttggaatat caagcaaatc ctgctgtctt aaaagatctc
    12601 aaagaaaagg ctaagaatat ttccagagag tattctgaag agcatctgtt acaaatctgg
    12661 ttggactttt atgagaaaca agccgcttta gggagaaagt aaaaagtgag gtaatctatg
    12721 cgaattggtt tatttacaga tacctatttt cctcaggttt ctggtgttgc gaccagtatt
    12781 cgaaccttga aaacagaact tgaaaagcag ggacatgctg tttttatctt tacgacgaca
    12841 gataaggatg tcaatcgcta cgaagattgg caaattatcc gcattccaag tgttcctttc
    12901 tttgctttta aggatcgtcg ctttgcctac cgaggtttta gcaaggcact tgaaattgct
    12961 aaacagtatc agctagatat tatccatact cagacagaat tttctcttgg cctgttgggg
    13021 atttggattg cgcgtgaatt gaaaattcca gtcatccata cctatcacac ccagtatgaa
    13081 gactatgtcc attatattgc taaggggata ttgatccggc cgagtatggt caagtatctg
    13141 gttagaggtt tcctgcatga tgtggatggg gttatttgcc ctagtgagat tgtccgtgac
    13201 ttgctatctg attataaggt caaggttgaa aaacgggtca ttcctactgg gattgaatta
    13261 gccaagtttg agcgtccgga aatcaagcag gaaaatttga aagaactgcg tagtaaacta
    13321 gggattcaag atggtgaaaa gacgttgctt agtctttcga gaatctccta tgaaaaaaat
    13381 attcaagcag ttttagcagc ctttgctgat gttctgaaag aggaagacaa ggttaaactg
    13441 gtagtagctg gggatggccc ttatctgaat gacctcaaag agcaagccca gaacctagag
    13501 attcaagact cagtcatctt tacagggatg attgctccta gtgagacggc tctttactat
    13561 aaagcggcgg atttcttcat ttcggcatcg acaagcgaaa cgcaaggttt gacctacttg
    13621 gaaagcttag ccagtggaac acctgtcatt gctcacggaa atccttattt gaacaacctc
    13681 atcagtgata aaatgtttgg agccttgtac tatggagaac atgatttggc tggtgctatt
    13741 ttggaagccc tgattgcaac accagacatg aatgagcata ccttatcaga gaaattgtat
    13801 gagatttcag ctgagaactt tgggaaacga gtgcatgagt tttatctgga tgccattatt
    13861 tcaaataact tccagaaaga tttggctaaa gatgatacgg tcagtcagcg tatctttagg
    13921 acagttttgt atcttccgca acaggtggtt gctgtacctg taaaaggatc tagacgcatg
    13981 ttgaaggctt caaaaacaca gttgatcagt atgagagact attggaaaga ccatgaagaa
    14041 tagaaagagg aacagctatg aaaaaaacaa ttaatgagaa gcggtcgtga taaaaagatt
    14101 gcgggtgttt gtgctggggt ggcccattat ctggatatgg atccgactat cgttcaagtc
    14161 atttggggtg ttcttacttg ctgttacgga gctggaattg tagcttacat tattttatgg
    14221 attatcgcac cagtagcaac tgactattga aaactagctc aattcatgct aagataatag
    14281 aaaatagaat gtaacgaagg agagaaaaat ggcatttgga gataatggaa atcgtaaaaa
    14341 aactatgttt gagaaaataa ccttgtttat cgtgattatc atgctagtag caagtttatt
    14401 gggaattttt gcaactgcaa ttggtgccct cagtaatcta taaaatagat tcaagaaaat
    14461 ttagtgactg ggatttccca gccctttttt aaagtgagaa gaaataatga gtatgttttt
    14521 agatacagct aagattaagg tcaaggctgg taatggtggc gatggtatgg ttgcctttcg
    14581 tcgtgaaaaa tatgtcccta atggaggccc ttggggtggt gatggtggtc gtggaggcaa
    14641 tgtggtcttc gttgtagacg aaggactacg taccttgatg gatttccgct acaatcgtca
    14701 tttcaaggct gattctggtg aaaaagggat gaccaaaggg atgcatggtc gtggtgctga
    14761 ggaccttaga gttcgagtac cacaaggtac gactgttcgt gatgcggaga ctggcaaggt
    14821 tttaacagat ttgattgaac atgggcaaga atttatcgtt gcccacggtg gtcgtggtgg
    14881 acgtggaaat attcgtttcg cgacaccaaa aaatcctgca ccggaaatct ctgaaaatgg
    14941 agaaccaggt caggaacgtg agttacaatt ggaactaaaa atcttggcag atgtcggttt
    15001 agtaggattc ccatctgtag ggaagtcaac acttttaagt gttattacct cagctaagcc
    15061 taaaattggt gcctaccact ttaccactat tgtaccaaat ttaggtatgg ttcgcaccca
    15121 atcaggtgaa tcctttgcag tagccgactt gccaggtttg attgaagggg ctagtcaagg
    15181 tgttggtttg ggaactcagt ttctccgtca catcgagcgt acacgtgtta tccttcacat
    15241 cattgatatg tcagctagcg aaggccgtga tccatatgag gattacctag ctatcaataa
    15301 agagctggag tcttacaatc ttcgcctcat ggagcgtcca cagattattg tagctaataa
    15361 gatggacatg cctgagagtc aggaaaatct tgaagaattt aagaaaaaat tgtctgaaaa
    15421 ttatgatgaa tttgaagagt taccagctat cttcccaatt tctggattga ccaagcaagg
    15481 tctggcaaca cttttagatg ctacagctga attgttagac aagacaccag aatttttgct
    15541 ctacgacgag tccgatatgg aagaagaagc ttactatgga tttgacgaag aagaaaaagc
    15601 ctttgaaatt agtcgtgatg acgatgcgac atgggtactt tctggtgaaa aactcatgaa
    15661 actctttaat atgaccaact ttgatcgtga tgaatctgtc atgaaatttg cccgtcagct
    15721 tcgtggtatg ggggttgatg aagcccttcg tgcgcgtgga gctaaagatg gggatttggt
    15781 ccgcattggt aaatttgagt ttgaatttgt agactaggag actggtatgg gagataaacc
    15841 gatatctttc cgagatgcgg atggtaattt tgtttccgcc gcagacgttt ggaatgaaaa
    15901 gaaattggaa gaactattta atcgtctcaa tccaaatcgt gccttgagat tggcacgaac
    15961 taaaaaggaa aatccatctc agtaaagaag ctaaaaaatc ccgtgcctca tcagacacgg
    16021 gattttgtgg tacgacaggc atgtatagca aactgaatct ggaatagcac agcatatctt
    16081 ctaaaatatt gttataaatt gatttgaatt tcaaaattaa attgtttgat tcttatctca
    16141 atttgttata gtatatctga tgtcaaagtt ctcggcgagt caaatagcga ttcccaagcc
    16201 tgactatcgt gaggtagcgg attaaaatgg tctggggata gaccgtttta agtctgacgc
    16261 tggaaataag aattgtcaga agaagggata gcgaaatcgt ggctctacga acaggaacgt
    16321 gataataagg cgtatatagc ggataagagg gcctcaaact ctaaagtcca aaaaggtagt
    16381 cgtaacctat atgcgtaaat cacgagagta attgaattcg tactaagatt ttctattttc
    16441 actgtaacct tttaacgtcc ttatatcttg tatacacgag gaaagatgta cgacttatcc
    16501 cgtgaggtct atcactataa agagaaaacg acagatagaa gtgatcctga gtcacggtta
    16561 tctttaaaat agattgtctg ataggacggt atgtataaaa cgcttctgtg aactgagaga
    16621 agggggagaa gttcttgcta aaatttagtt gaacagccgt attccgatac ttagataaga
    16681 gatctagtct tagctcctac tcagttttag gggataaaaa aggggaaata gcgattcgag
    16741 aaagattata ctcttcgaaa atctcttcaa atcacgtcaa tatcgccttg ccgtatgtgt
    16801 aggatactga ctacgtcagt tccatctaca acctcaaaac agtgttttga gcaacctgcg
    16861 gctagtttcc tagtttgatc tttgattttc attgagtatt agtaattcag ttactaactc
    16921 gtcaactctg atttatccaa taaaattgaa aaggatggaa aaaaggataa atttatgata
    16981 tactttattt tgaagacctt attagaaatc ttgaaagagt attgaaaact tagaatgaga
    17041 aaaattgtta tcaatggtgg attaccactg caaggtgaaa tcactattag tggtgctaaa
    17101 aatagtgtcg ttgccttaat tccagctatt atcttggctg atgatgtggt gactttggat
    17161 tgcgttccag atatttcgga tgtagccagt cttgtcgaaa tcatggaatt gatgggagct
    17221 actgttaagc gttatgacga tgtattggag attgacccaa gaggtgttca aaatattcca
    17281 atgccttatg gtaaaattaa cagtcttcgt gcatcttact atttttatgg gagcctctta
    17341 ggccgttttg gtgaagcgac agttggtcta ccgggaggat gtgatcttgg tcctcgtccg
    17401 attgacttac accttaaggc gtttgaagct atgggtgcca ctgctagcta cgagggagat
    17461 aacatgaagt tatctgctaa agatacagga cttcatggtg caagtattta catggatacg
    17521 gttagtgtgg gagcaacgat taatacgatg attgctgcgg ttaaagcaaa tggtcgtact
    17581 attattgaaa atgcagcccg tgaacctgag attattgatg tagctactct cttgaataat
    17641 atgggtgccc atatccgtgg ggcaggaact aatatcatca ttattgatgg tgttgaaaga
    17701 ttacatggga cacgtcatca ggtgattcca gaccgtattg aagctggaac atatatatct
    17761 ttagctgctg cagttggtaa aggaattcgt ataaataatg ttctttacga acacctggaa
    17821 gggtttattg ctaagttgga agaaatggga gtgagaatga ctgtatctga ggacagcatt
    17881 tttgtcgagg aacagtctaa tttgaaagca atcaatatta agacagctcc ttacccaggc
    17941 tttgcaactg atttgcaaca accgcttacc cctcttttac taagagcgaa tggtcgtggt
    18001 acaattgtcg atacgattta cgaaaaacgt gtaaatcatg tttttgaact agcaaagatg
    18061 gatgcggata tttcgacaac aaatggtcat attttgtaca cgggtggacg tgatttacgt
    18121 ggggccagtg ttaaagcgac cgacttaaga gctggggctg cactagtcat tgctgggctt
    18181 atggctgaag gtaaaactga aattaccaat atcgagttta tcttacgtgg ttattctgat
    18241 attatcgaaa aattacgtaa tttaggagcg gatattagac ttgttgagga ttaaaccgta
    18301 gaggtgttta tgaatatttg gaccaaatta gcaatgtttt ctttttttga aacggatcgc
    18361 ttgtatttgc gtcctttctt ttttagtgat agtcaggact tccgcgagat agcttcaaat
    18421 ccagaaaatc ttcaatttat tttcccaacg caggcaagtc tggaagaaag tcaatatgca
    18481 ctggccaatt actttatgaa gtcccctttg ggagtgtggg caatttgtga ccagaaaaat
    18541 caacaaatga ttggttctat taaatttgag aagttagatg aaatcaaaaa agaagctgag
    18601 cttggctatt ttttgagaaa agatgcttgg tcgcaaggat ttatgacaga ggttgttaga
    18661 aaaatttgtc agctttcttt tgaggaattt ggcttaaaac aattatttat cattacccac
    18721 cttgaaaatg aagctagcca aagagttgct cttaagtctg gatttagttt gttccgtcag
    18781 tttaagggaa gtgatcgtta cacaagaaaa atgcgggatt atcttgaatt tcggtatgta
    18841 aaaggagagt tcaatgagta agcatcagga aattctaagc tatttggagg aattaccagt
    18901 aggtaaaagg gtcagtgttc gtagcatttc gaatcatcta ggagttagtg atggaacagc
    18961 ctatcgagct attaaagaag ctgaaaaccg tggaattgtg gagacccgtc ctagaagtgg
    19021 aacaattcgt gttaaatccc agaaagttgc tatagataga ttaacgtttg ctgaaattgc
    19081 agaagtgact tcttctgagg ttctggctgg gcaagaaggt ttagagagag aatttagtaa
    19141 gttttcaatt ggtgccatga ctgaacaaaa tatcttgtct taccttcatg atggggggct
    19201 cttgattgtc ggagaccgaa cccgtattca gttgctagcc ttggaaaatg aaaatgcagt
    19261 tctggttaca gggggatttc aggttcatga tgatgtgctt aaactggcca atcaaaaagg
    19321 gattcctgtt ctaagaagta agcatgatac ctttaccgtc gctaccatga tcaataaagc
    19381 cttgtcaaat gtccaaatca agactgatat tctgacagtt gagaaacttt atcgccctag
    19441 tcatgagtat ggttttctga gagagacaga tacagttaaa gattatttgg acttggttcg
    19501 taagaatcgt agcagccgtt tccctgttat caatcaacat caggtcgttg ttggcgttgt
    19561 aaccatgaga gacgctggtg ataaatcacc aagcacgaca attgataagg ttatgtctcg
    19621 tagtctattt ttggttggat tatcgacaaa tattgccaat gtgagtcaac ggatgatcgc
    19681 agaagacttt gaaatggtac cagttgttcg aagcaatcaa actttgcttg gcgttgtgac
    19741 gcgacgagat gtcatggaga agatgagccg ttcccaagtt tcggctctac caactttttc
    19801 tgagcagatt ggacaaaagc tctcttatca ccatgatgaa gtagtcatta cagtggaacc
    19861 ctttatgcta gaaaaaaatg gagttttggc taatggtgta ttggcagaaa ttctgaccca
    19921 catgacccaa gatttagttg ttaatagtgg tcgcaatctc attatcgagc agatgctgat
    19981 ctactttttg caggccgttc agatagatga tatattgcgc attcaggcac ggattattca
    20041 tcatacgaga cggtcagcta taattgatta cgatatttat catggtcacc agattgtttc
    20101 aaaagcaaat gtgactgtta aaattaatta gaaactagga gaaaagatga taacattaaa
    20161 atcagctcgt gaaatcgaag ctatggacaa ggctggtgat tttctagcaa gtattcatat
    20221 aggcttacgt gatttgatta agccaggcgt agatatgtgg gaagttgaag aatatgtccg
    20281 ccgtcgttgt aaagaagaaa atttccttcc acttcagatt ggggttgacg gtgccatgat
    20341 ggactatcct tatgctacct gttgctctct taacgatgaa gtggctcacg ctttccctcg
    20401 tcattatatc ttgaaagatg gtgatttgct caaagttgat atggttttgg gaggtcccat
    20461 tgctaaatct gacctaaatg tctcaaaatt aaacttcaac aatgttgaac aaatgaaaaa
    20521 atacactcag agttattctg gtggtttagc agactcatgt tgggcttatg ctgttggtac
    20581 accgtccgaa gaagtcaaaa acttgatgga tgtaaccaaa gaagctatgt acaagggtat
    20641 tgagcaagct gttgttggaa atcgtatcgg tgatatcggt gcggctattc aagaatacgc
    20701 tgaaagtcgt ggttacggtg tagtgcgtga tttggttggt catggtgttg gcccaactat
    20761 gcacgaagaa ccaatggttc ctaactatgg tattgcaggt cgtggactcc gtcttcgtga
    20821 aggaatggtc ttaaccattg aaccaatgat caatacaggc gattgggaaa ttgatacaga
    20881 tatgaaaact ggttgggcgc ataagaccat tgacggtgga ttgtcatgtc agtatgaaca
    20941 ccaatttgtc attacgaaag atggacctgt tatcttgact agccaaggtg aagaaggaac
    21001 ttattaataa aaagtgaaaa gactactgga agtttattat gaaaaaatcc agtagatctt
    21061 ttcataataa aacgcattgt atcaagtgtt aggggctgat atcatgcgtt tttctgcttt
    21121 taagattttt tccaactctg tttgtaagcg catcataaca aagggtctag gattcagggc
    21181 tctcctccta tatactatta gtaaagtaaa actaagggag gatattttag tgtcgcagtc
    21241 tattgttcct gtagagattc cacaatattg tcgttttgat tctaaaaaga gaaatggaat
    21301 tctgtttaat gttcgtattg ccaatcttaa atttaccttt tttagattag acttcctgcg
    21361 aaacaaaaca tggtatagta gttctatgaa tgatgaagca agtaaacaac taac
//
LOCUS       DAVAZT010000039        21312 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVAZT010000039 DAVAZT010000000
VERSION     DAVAZT010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21312
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.039"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(57..176)
                     /locus_tag="VQT45_001390"
     CDS             complement(57..176)
                     /locus_tag="VQT45_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HET2359706.1"
                     /translation="MDFKSFIIGLVVGIFGPYMYNLIRKIFSKFPKKDTDSTP"
     gene            complement(179..409)
                     /gene="blpU"
                     /locus_tag="VQT45_001391"
     CDS             complement(179..409)
                     /gene="blpU"
                     /locus_tag="VQT45_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HET2359707.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAARGLQ
                     LGIKTGTWQGAATGAAGGAILGGVAYAATCWW"
     gene            complement(478..747)
                     /gene="blpJ"
                     /locus_tag="VQT45_001392"
     CDS             complement(478..747)
                     /gene="blpJ"
                     /locus_tag="VQT45_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HET2359708.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            complement(1214..1411)
                     /gene="blpI"
                     /locus_tag="VQT45_001393"
     CDS             complement(1214..1411)
                     /gene="blpI"
                     /locus_tag="VQT45_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HET2359709.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            1693..2280
                     /locus_tag="VQT45_001394"
     CDS             1693..2280
                     /locus_tag="VQT45_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HET2359710.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            2273..3862
                     /locus_tag="VQT45_001395"
                     /pseudo
     CDS             2273..3862
                     /locus_tag="VQT45_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864064.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
     gene            3873..5234
                     /locus_tag="VQT45_001396"
     CDS             3873..5234
                     /locus_tag="VQT45_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HET2359711.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMDESQKTAL
                     ETQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLANSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LIASQGQTQGTAEEPFLSQINQSIASLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLLLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     SIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            5291..5446
                     /gene="blpC"
                     /locus_tag="VQT45_001397"
     CDS             5291..5446
                     /gene="blpC"
                     /locus_tag="VQT45_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HET2359712.1"
                     /translation="MDKKQNLTSFQELTTTELNQIIGGGWWEDFLYRFNIIEQKNTKG
                     FHQPIQL"
     gene            complement(5490..6830)
                     /locus_tag="VQT45_001398"
     CDS             complement(5490..6830)
                     /locus_tag="VQT45_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2359713.1"
                     /translation="MNVAWILLYTLVTHGLKIVIFFKVDGISLTFERIFKAFLFKILL
                     AVVFGMLGYMVGNTYLSYFMEPLYGIGLSFLLLRELPKKLLLFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDDYSFIWLCIIIFNFFISLAFLKWLDYDFTSLRKGILDKDFQK
                     SLTQINWIMGAYYLVIQNLSYFEYEQGIQSTTVRHLILVFYLLFFMGIIKKLDTYLKD
                     KLHERLNQEQDLRYREMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLKDSSEKLQDNKYDLGRLVNIRDKALKSLLAGKFLKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTVVSILCDNAIEASVEACQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQDHVFRQVLTVIHIE"
     gene            complement(6844..7581)
                     /locus_tag="VQT45_001399"
     CDS             complement(6844..7581)
                     /locus_tag="VQT45_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2359714.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKEHHITPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(7586..7924)
                     /locus_tag="VQT45_001400"
     CDS             complement(7586..7924)
                     /locus_tag="VQT45_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2359715.1"
                     /translation="MKHMIIQTQKTVYKVNVDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQYGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            8201..8530
                     /locus_tag="VQT45_001401"
     CDS             8201..8530
                     /locus_tag="VQT45_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET2359716.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(8698..9747)
                     /locus_tag="VQT45_001402"
     CDS             complement(8698..9747)
                     /locus_tag="VQT45_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2359717.1"
                     /translation="MKDLFLKRKQAFRKECLCYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEAIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(9744..10475)
                     /locus_tag="VQT45_001403"
     CDS             complement(9744..10475)
                     /locus_tag="VQT45_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2359718.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            10543..10953
                     /locus_tag="VQT45_001404"
     CDS             10543..10953
                     /locus_tag="VQT45_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET2359719.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMNATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            10963..11250
                     /locus_tag="VQT45_001405"
     CDS             10963..11250
                     /locus_tag="VQT45_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359720.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            11412..11651
                     /locus_tag="VQT45_001406"
     CDS             11412..11651
                     /locus_tag="VQT45_001406"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359721.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDRTDEVSNHTHDKPTLTWFEEIFEEYHSPFHN"
     gene            complement(12001..13137)
                     /gene="dnaJ"
                     /locus_tag="VQT45_001407"
     CDS             complement(12001..13137)
                     /gene="dnaJ"
                     /locus_tag="VQT45_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HET2359722.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(13342..13695)
                     /locus_tag="VQT45_001408"
     CDS             complement(13342..13695)
                     /locus_tag="VQT45_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000115730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359723.1"
                     /translation="MSVNKNNLSDIADYHEKIKFFEELFNLDYNPTEMLVTVERNGNV
                     IYKEFTEVAVGKSKYDHTSVFKDVMIYFSDHICQELHLYKTQDPHYNKFEFDLAKRSL
                     KITTRDNTTIFISNE"
     gene            complement(13708..15531)
                     /gene="dnaK"
                     /locus_tag="VQT45_001409"
     CDS             complement(13708..15531)
                     /gene="dnaK"
                     /locus_tag="VQT45_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HET2359724.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(16011..16535)
                     /gene="grpE"
                     /locus_tag="VQT45_001410"
     CDS             complement(16011..16535)
                     /gene="grpE"
                     /locus_tag="VQT45_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HET2359725.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(16562..17596)
                     /gene="hrcA"
                     /locus_tag="VQT45_001411"
     CDS             complement(16562..17596)
                     /gene="hrcA"
                     /locus_tag="VQT45_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HET2359726.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTGLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLEAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(17760..18269)
                     /locus_tag="VQT45_001412"
     CDS             complement(17760..18269)
                     /locus_tag="VQT45_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HET2359727.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTTTFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            18877..20814
                     /locus_tag="VQT45_001413"
                     /pseudo
     CDS             18877..20814
                     /locus_tag="VQT45_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            20812..21312
                     /locus_tag="VQT45_001414"
                     /pseudo
     CDS             20812..21312
                     /locus_tag="VQT45_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819352.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         6698 a         4437 c         3832 g         6345 t
ORIGIN      
        1 attaaagaaa ctcccctgta aattaagcta gcaaatacag gggagaaatt tattttttag
       61 ggggtactat ctgtatcctt tttgggaaat tttgaaaata tttttctaat taaattatac
      121 atataaggac caaatatacc aactactaaa ccaataataa aacttttaaa atccataatt
      181 accaccaaca tgttgctgca taggctacac ctccaagtat agctccaccc gcagcaccag
      241 ttgctgcacc ttgccatgtt cctgttttaa tgcctagttg aagacctctt gctgctgctc
      301 ctccaacacc tgctttggca aaatctcccc aattgcatcc gccaccttca acgcaagcaa
      361 gcatttcagt atccataaca gaaaattgtg acatcatttt tgtatccatg acaaatactc
      421 cttttttaaa aaactaaaat aaatcagaat agaatcctca taattttact ataagtctta
      481 ccaacttagt cccaatttat caccaaccat acctcctaag catgttaatc cacccccaat
      541 tgcaccaatg tgtgctccaa caaatgcacc agcaagtcca gctactccta aagtggccaa
      601 acctgctcca gttccaccag ttataattcc cgtagtgact cctgtaatca gtgcattttg
      661 acaatcagtg gagctatacc ccccttcaac tttcgcaagc atttcagtat ccataacctc
      721 taactgtgac aacatttttg tattcatgat gaatacctcc tttttatttt caatttgtta
      781 ccaaagtctt aaattcaata aacaaataga ttttttatag tatctttttg attttcttaa
      841 aaaagtatat acgtctacta tcttcttaaa ggtagcagta cctatttttt agtctaagat
      901 ttcaataatc ttgagtatct aaaatatctt aatttcgtta ttctccttgc aataaaaagt
      961 tttactatac tatttattaa cttgcagaaa gcaaaaaata ttagtaaata atagtttata
     1021 gttaagtttt ttattcctac caatccatca actaagtaaa gcatcaacga ttacataaac
     1081 gattgataat ataattaaaa ttttgctaac tatcttattc tcatcattct tagataactt
     1141 tgatattttg taagtaagta aataagacag taaattaata gcgataataa tactatattt
     1201 aagaatcata atcttacaaa gaggacataa ttcctgaacc tacacaaata agtgttgctg
     1261 ctcccccagt tatcggacca gtcgcagcag ctaatagtac tgctccaata caaccaccga
     1321 ttgcagatcc taaattgcct cttcctccac taactatttc gagttcttca ttatccataa
     1381 cagaaaattg ttccatcatt tttgtattca tgacaaatac tccttttttc tttttttatt
     1441 tttgtcttgt tgtaactttg ataagtttag tatatcatcg ttttttaaaa tttttcatcc
     1501 agatcttgaa ttgtcatcga aacgtcttga attagctttt ttatttcaag ccacctctaa
     1561 atgtttaaaa aaaataattt ctaatcactt ttttaccatt caggaagttt taatgactat
     1621 tcaagatttc ataaaatatg aacttagttt tatgacataa tagacctatc cactatatga
     1681 aaagaattgc caatgacttc ttataaacgt acatttgttc ctcaaataga tgcgagagac
     1741 tgtggtgtcg ctgccttagc ctcgattgct aaattctatg gttcagattt ttctctagct
     1801 cacttgagag aacttgcaaa gaccaataaa gaagggacga ctgctcttgg cattgtaaaa
     1861 gccgctgatg aaatgggctt tgaaacaaga cctgttcaag cagataaaac gctctttgac
     1921 atgagtgatg tcccctatcc atttatcgtt cacgttaaca aagaaggaaa actccaacat
     1981 tactatgttg tctatcaaac aaagaaagac tatctgatta ttggtgatcc tgacccttct
     2041 gtaaaaatca ctaaaatgtc aaaagaacgc tttttctatg aatggactgg agtagctatt
     2101 tttctagcta ccaaacccag ctatcaaccc cataaagata aaaagaatgg tctactaagc
     2161 aagcttcctt cctctgattt tcaaacaaaa atctctcatt gcttacattg ttctctcaag
     2221 cttattggtc actattatca atataggtgg ttcttactat ctccaaggaa tcttggatga
     2281 atacattcca aatcagatga aatcaacttt aggaatcatc tcagttggtc tggttatcac
     2341 ctaggttatc acctatatcc tccaacaagt catgagcttc tccagagatt atctcctaac
     2401 cgttctgagc cagagattaa gcattgatgt gattttatcc tatattcgcc atatttttga
     2461 acttcccatg tctttctttg cgacacgtcg tacaggagaa atcatttcac ggttcacaga
     2521 tgctaactct attatagatg ccttggcttc taccattctt tctctttttc tggatgtttc
     2581 tattctgatt cttgtagggg gagtcttgct ggcacaaaac cctaatctct tcctcctttc
     2641 tcttctttcc attcctatat acatgttcat catcttttct tttatgaaac cttttgaaaa
     2701 aatgaaccat gatgtcatgc aaagtaattc tatggttagc tctgccatta tcgaagatat
     2761 caacgggatt gaaactataa agtcgctcac gagtgaagaa aatcgctatc aaaatataga
     2821 cagcgaattt gtagattatt tggaaaaatc ctttaagctc agtaaatatt ctattttaca
     2881 aacgagttta aagcagggaa caaaattagt tctgaatatc cttatcctat ggtttggcgc
     2941 tcaattagtc atgtcgagta aaatttctat cggtcagctg attaccttta acacactttt
     3001 ttcttacttt acaactccta tggaaaatat tatcaacctc caaaccaaac tcccatctgc
     3061 gaaggtcgct aataaccgtt tgaacgaagt ctatctagtc gaatctgaat ttcaagttca
     3121 agaaaaccct gtccattcac attttttgat gggcgatatt gaatttgatg acctttctta
     3181 taagtatggt tttggacgag ataccttaac agatattaat ctcacgatta aacaaggaga
     3241 taaggttagc ctagttggag ttagtggttc tggtaaaaca actttagcca aaatgattgt
     3301 caatttcttt gaaccctaca aagggcatat ttccatcaat catcaggata ttaaaaacat
     3361 tgataaaaaa gtcttgcgcc gtcatattaa ttacctaccc caacaagcct atatctttaa
     3421 tggctctatc ttggaaaatt taaccttggg cggtaatcat atgattagcc aagaagatat
     3481 tctaagagct tgtgaattag ctgaaatccg tcaagacatt gaaagaatgc ctatgggcta
     3541 tcaaactcag ctctctgatg gagctggtct atcaggagga cagaagcaac gaatagccct
     3601 cgctcgtgct cttttaacta aatctcctgt tttaatacta gacgaagcta ctagcggtct
     3661 tgatgtcttg actgagaaaa aagttataga taatcttatg tccctaactg ataaaaccat
     3721 tctctttgta gcccatcgtc tcagtatagc cgaacgaact aaccgtgtca ttgttcttga
     3781 ccaggggaaa atcattgaag ttggtagtca ccaagagtta atgcaggcgc aaggcttcta
     3841 ccatcatctg ttcaataaat aaggagaatg tcatgaatcc taatcttttt agaagcgtcg
     3901 agttttatca gagacgttac cataactatg cgacagtgtt aattatacct ctttcattac
     3961 tgtttacttt catcttgatt ttctcccttg ttgccacaaa agaaattact gttacttccc
     4021 aaggagaaat cgcccctaca agtgtcattg catccattca gtcaaccagt gataatccta
     4081 tccttgctaa tcatttagtg gcaaatcaag tagttgaaaa aggtgactta ctcatcaaat
     4141 actctgaaac aatggatgag agtcagaaaa ctgccttaga aactcaatta caaagacttg
     4201 agaagcaaaa agaaggactt ggaattttga aacaaagttt agaaaaagcg actgatcttt
     4261 tttctggcga ggatgagttt ggctaccata atacctttat gaattttact aaacaatccc
     4321 atgatattga actgggtatc acaaagacta acaccgaagt ttcaaatcaa gctaatcttg
     4381 ccaatagcag ttcatcagcc atcgaacaag aaattacaaa agttcaacaa caaattggag
     4441 aatatcaaga gttgagagat gctatcataa ataacagagc acgcttacca actggcaatc
     4501 cgcaccagtc aattttaaat cgttatctta tagcctctca aggacaaaca caaggaacgg
     4561 cagaggagcc atttttatct caaattaatc aaagtattgc aagtcttgaa tcatctatcg
     4621 caagcctcaa aattcagcaa gctggtatcg gaagtgtagc aacttatgat aatagtttag
     4681 caaccaaaat tgaagtactc cgcactcagt ttttacaaac agcctcacag caacaactaa
     4741 ccgtggagaa tcaattaaca gaattaaaag tacaactaga tcaagcgaca cagcgcttag
     4801 aaaataatac cttaaccgct ccaagtaaag gtatcgttca tctgaacagc gaatttgaag
     4861 gtaaaaatag aattccaact ggtacagaaa ttgctcaaat attccctgtc atcacagata
     4921 caagagaagt actaatcact tactacgtat catctgacta tctcctctta ctagataaag
     4981 gacaaactgt aagattaaaa ctggagaaga ttggaaatca cggcaccacc atcatcggcc
     5041 aacttcagag tattgatcaa actcctacca gaacagagca aggcaatctc tttaaattaa
     5101 ccgctcttgc aaaactatct aacgaggata gtaaactcat ccaatatggc ttacaaggtc
     5161 gcgtcactag tgtaactaca aagaaaacat attttgatta tttcaaagat aaaattttaa
     5221 cacattctga ttaattttca gataacactc tataactatt tattatctta tcaaaaagga
     5281 gaatcataac atggataaga aacaaaacct aacttcattt caagaactaa caactaccga
     5341 actcaaccaa attataggtg gaggatggtg ggaagatttc ttatatagat ttaatataat
     5401 tgaacaaaaa aatacaaaag gatttcatca gccaatacaa ctataaaaaa acaagaccaa
     5461 gagaacgcac tctcggtctt attttttctt cattctatat gtattacagt aagtacctga
     5521 cgaaaaacgt gatcttggca ggtggtattg agactggtat tgggatgact ttccacaatt
     5581 ttcataacgg tatagagacc aactcctctc tcctcccctt tagaacttgc tccaaaggag
     5641 aagatttcag aaatatcgat tccctcttct ttgatggaat tttcaatgat aaaggtctcc
     5701 tgtgctccat tttttaaaaa ggcaattgaa acatgaggtt gacaggcttc tacactagct
     5761 tcaatagcgt tgtcacaaag gatagacaca acggttagaa aatcaagtag actcatcccc
     5821 tctacctgaa tctcctctgg aacttcgaca ttaaagacaa tgttcttatc tctagctttt
     5881 agaaatttcc ctgctaggag acttttgagg gctttatcac gaatattcac caatcgacca
     5941 aggtcatatt tattgtcctg caatttttca ctagaatcct ttaagaccga gtcgtagatc
     6001 tcttttatct gctccatatc ctcctcttca atgcccagac gtaagctagt caagaggttg
     6061 gtgtagtcat ggcgaaaact ccgtacttcc ttataaagct cctctatatg ccgactatac
     6121 cgctccatct ctctgtagcg caagtcctgc tcttggttca gtctctcatg gagtttgtcc
     6181 ttcaaatagg tatccaattt cttgataatc cccataaaaa agagcaggta aaagactagg
     6241 atgagatggc gaacagtcgt tgattgaatc ccctgttcat attcaaagta agacagattt
     6301 tgtatcacca aatagtaagc ccccattatc cagttaatct gagtcaggga cttttgaaaa
     6361 tctttatcga gaatcccctt tctcaagcta gtgaaatcat agtccaacca tttcaaaaaa
     6421 gctagagaaa tgaagaaatt gaaaattatt atacataacc aaataaatga gtagtcatca
     6481 tatacttgcc cttgtcccaa aaatggaagc acaaaatagg aaacacctct ataaaagaga
     6541 ttcactaata tcattggaaa gagaccataa aagagaagga gttttttagg aagttctctt
     6601 aacaataaga aagataagcc tatgccgtac aagggttcca taaaataaga tagataagta
     6661 tttcctacca tatagccaag cattccaaaa acaacggcca acagtatctt aaaaagaaag
     6721 gccttaaaaa tcctctcaaa agtgagacta attccatcta ccttaaagaa tatgacaatt
     6781 tttaatccgt gagtaacaag tgtatacaac aatatccaag caacattcat aaactctcct
     6841 agctcagtgt aagttattaa tagcctcaga cacttccctg accttataac gcgcgattag
     6901 acaacttcca ccattgggaa agaaaagcag tttttctttc ttatctaaat gcaccacatt
     6961 ggcaggattg atgagaaaag agcgatggca ctgcaagaga cgaggctcct gcttgagaac
     7021 ctcctctaga ctcgctgtaa attccagcct gtctgtcttg gtatagagaa taacacgatg
     7081 gggtcttgtg gacgtttcga gatagtaaac ctctttaaaa ggatactgga attgagcaaa
     7141 ttttgattta aagtaaaagc aatcttccgc tagactttta ctgtcttgac cattggcata
     7201 gaggagggct gtctcgatac gagattcaaa ctcctctgcc gaaagggcct tatcaatata
     7261 gtccagagca gacacttggt agcgaaagga caggggcata aactccgagt gagtcgtcac
     7321 aaagacaatc agggcatacg gatcccgatc ccgaatcttt ctagccactt ccagaccctt
     7381 catctcctca tttcgaatct caatatccaa aaagaatagc tgatgggccc ccttctcatg
     7441 cacctctgcc agcagttggt ctggcttgcc aaatacctca aaagagctgg gagtgatatg
     7501 atgttccttc aagagtttct caatcgtcgt ttcaatccta gtctgttggg aaaaatcatc
     7561 ctctaaaaca aatattctca tcttcttact ctccctcttt caaccatttt tgacgaattt
     7621 ctctatagcg acgtctggca tacttgacag cgtattgacc ttcttctccg agaaaaagga
     7681 ttctttcttg aaaatcaatc gattttaatt tatcaagatt aaccaaacaa tttcgatgac
     7741 atctcatcaa ggtttcccca tattggttct caagattact taaattttga agcatattaa
     7801 aactagcttc ttctgtaaca atctgtacgg tatgggcttt agttggatgt gtttggatat
     7861 agtagatatc gtcgacgttt actttataga ctgttttctg cgtctgaata atcatatgtt
     7921 tcattggatt ctcctcctaa gaaaagaata acagaaaagt tctagcccaa gcccacccaa
     7981 tcctaaacag tctttgaaag ctcctaaaag gattattttt ctacaacatc atgatgagct
     8041 tacaactatt ttatcataaa attcactcag cgcaattcaa gacatttcaa tgacaattaa
     8101 agatttgaat aaaaaaaaag aattaaaaat gataaactaa cagtatcaaa acacagttgc
     8161 cagaagtaag actggcaccc agattaaagg aggcattccc atgacagata cagaccccat
     8221 caaaagagct catactttga ttactgactt aaacaaagcc taccaagcat gcaaacaggc
     8281 aagcgctgac gacgtccgct ttcaggagca attaaactct attcttggtt ttttagccaa
     8341 ggctgaaaca gtggataatc gattcttgat tgaactagaa aaattttacc agacttccag
     8401 tcttctcatg ggactcagcg ctcttgatcc agatgctcca actcgcgccg cttggcgggc
     8461 ctatgaccgc ttccactttg accaagtcaa gaccaagtta atactcaatg aaaatcaaag
     8521 agcaaactag gaagctagcc gcaagctgta cttgagtacg gtaaggcgac gctgacgtgg
     8581 tttgaagaga ttttcgaaga gtataagtct ctacggacca accattatcc tgtagtaaca
     8641 aaaaagaagc tgagacagac tgaactcaac ttctttttta gtgtcgtatc agcaatgtta
     8701 gtcctgcatc tgacgtttta cctgataagg caaatacaag actagtaaaa ccaaaccagc
     8761 tcctagtaag gctagaaggg ccagtttttc ttggaaggta atcaacccaa caactaattc
     8821 cacaagtaaa acaaaactgg tcaatcctcg aactacctcc tgtaagcctt tttccttttg
     8881 ccccttgtcc agcggaaaga gttgggtcaa atactggtag tcaaaggcat gatagagggc
     8941 cagcaactgg aagagcaaga ggtagttaaa gagaactacc actgctgtcg caatccaagc
     9001 ttgctcgata aaaacctgcg ccagtacgga aagtaataga agacgaagac tgagagcaaa
     9061 gaggtcgcca tttcgcagat aagaacgcag atagagattt tgccaaatct tcccaggcac
     9121 cttctgaaca gcctttaaga taaagtccag ataggcacga cgcttaacgc tgtttgaaat
     9181 tcccttgacc tgcgtaaaga gggcaaagaa acgaagcaag acttgcttac gcttgctttc
     9241 ttgagaaata acatagtccc agtccagtcc agtttcagta aaaaatttgc tggccttttg
     9301 acgaaagtgg aaatattttc ctacccccaa taaaagcaca tatagcagaa aaactggcaa
     9361 gccataaccc attgctaaaa ataaaggcgc aaataacagc aagaaaaggg tctgtacaaa
     9421 gagccaaaag actagggaaa tgccagtttg acgcttgaga tggagcttga ttgcctcttc
     9481 tccaactaag agaaagagct tgtctggagc ctccatatag gtggcaattc ctccccaaag
     9541 taagagtaaa acagacgtaa ttcctacaaa caaaaggata ggccaatgat tttcaggaaa
     9601 atgttgtaag agttgactgt actggtaggc tagaaagccc aacaggacaa gcaggaacaa
     9661 gacaaagtgg tcattgagca catagcgcag ataacaaaga cactccttac gaaaggcctg
     9721 ctttctcttt aaaaacaagt ctttcataga tcctcctctt tggtcagagc caagtaaata
     9781 tcattcaaac tagcctcagg catatcaaag gcttcacgta gttgcaggag attgcctttg
     9841 gcacgcacct ctcccttgtg aagaatgaca aaggcatcac acatcttttc cgccgaatcc
     9901 agcacgtggg tactcatgag aatagacttg cccttttgct tctccacttc caaaagctga
     9961 atcaaatcag aaatagccag cggatcaaga ccaaggaaag gctcatccac gatgaaaaga
    10021 cttggatcca ccacaaaagc acagataatc atgaccttct gcttcatccc ttttgaaaaa
    10081 tgaacaggga accagtctaa tttctgttcc aaacggaaca tttttaacaa gggctctact
    10141 cgttcgaaag ccactttttg ctcaataccg taagccatag caaccgtttc gatatgctct
    10201 ctgagggtca attcctcata cagactaggc gtctcaggaa tgtagccaat ctgcttgcgg
    10261 tagctagtcg catctccttg cagagtcagg ccattgatat tgatggagcc actataaggt
    10321 gccaacagac cgataatctc attgatcgtc gttgatttcc cagcaccatt gagaccaatc
    10381 aaaccgacca actgcccact ttcaacagta aaggacacat ctttcaaaac aggaacatga
    10441 acatagccac ctgtcaggtt tttaatttct aacatatttt ctccaaatct ggtataatgt
    10501 agctatatta tatcaaaatt cagtacagta gaggtagatt ttatgtcaga ttgcattttt
    10561 tgtaaaatca tcgcagggga aattcctgct tcaaaagtat atgaagatga gcaggtcctt
    10621 gcctttcttg atatctctca agtaacacta ggacacacct tggtcgtgcc aaaagaacac
    10681 tatcgcaatc ttttggagat gaatgctacg agcgccagcc aactctttgc ccaagtacca
    10741 aaagtagctc aaaaagtcat gaaagtcact aaggctgctg gtatgaatat catttccaac
    10801 tgtgaagaag tcgctggtca aacagttttt catactcacg ttcaccttgt gcctcgctac
    10861 agtgctgacg atgacctcaa gattgatttt atcgcccacg aaccagactt tgacaaactt
    10921 gctcaagtcg ctgaaaccat caaaaacgct taaggagttg ctatgaaatt atccaaccta
    10981 ctgctatttg caggagctgc agccggaagt tatctggtta caaaaaatcg ccaaaccatc
    11041 acagatgaag tcttgaatac cactgaccgc gttcaagcta tcaaagacga tgtggatatt
    11101 atccaaaata gcctgcaaat catcgaccag caaaaagaac ttatcaagga ataccaagaa
    11161 gacttgactt acaagtttaa ggtcttggaa aaggatatcc agactagact agctgtgata
    11221 aaagaaatgc agggaactga agataagtaa aaagagcccc ccggctcttt tttaaaacgt
    11281 aaacaagtta tagtgaattg aatttagaat agcacatcat agtttctaaa gcattgttag
    11341 agattacttt aaaatcctct tatcaatttg ttcatattct atttcaatct actatatata
    11401 tcccatcaac tatgcatcat aatttaggta actcatactc aataaaaatc aaaaagcaaa
    11461 ctagaaagct aggcacagac tgctcaaaac accgttttaa ggttgtggat agaactgacg
    11521 aagtcagctc aaaacactgt tttgaggttg tggatagaac tgacgaagtc agtaaccata
    11581 cccatgacaa gccgacgctg acgtggtttg aagaaatttt tgaagagtat cattcaccat
    11641 ttcacaacta aatcgaagac tttctgccgt aatgaaaaca cctgaaacag cttggtttca
    11701 gctgtccgga aactttaaga cttaggttca aagtttaggt atggaacttc gaaggaggtc
    11761 gctaccgtcc gtcattactt aggaaagtct taaaaaatct ataaagtaaa aagagcccga
    11821 cagctctttt tgtttatact caatgaaaat caaaaagcaa actaggaaac tagccacggg
    11881 ctgctcaaaa cactgttttg aggttgtaga tacgactcac atatatacgg caagccgacg
    11941 ctgacgtggt ttgaagagat tttcgacgct gacgtggttt gaagagattt tcaaagagta
    12001 ttattctcca tcaaaggcat ctttaatatg gtcaaagaag ccttttttct ttggatttac
    12061 tttcaagtca ccagcagccg cgaattcttt caaggctact ttttggcggt cgttcaagcc
    12121 tgtcggtgtt acgacattaa cagtaacgta ttggtcacca actgcaccgc cacgaaggct
    12181 cggtgccccc ttactacgta ggcggaattt cttaccagtc tgagttccct ctggaataac
    12241 caattcaaca tcaccgtgaa cagttggaat atctactgta tcaccaagag ccgcttggac
    12301 aaagttgagg ttgagattgt agaagatagt cgttccttca cgttcaaact tgtcgctagc
    12361 ttctacagaa actactacat acaagtcccc ataaggtcca ccgttaaagc ctgcttcgcc
    12421 ttgaccagcg aggcgaattt gttgacctgt ttccacacca gcagggattt tcacatgtac
    12481 gctatgagct tgtttctcat gacctgttcc atgacaggtt gtacatggat atttgatttc
    12541 ttttcctcga ccgtgacaga catcacaggt tacttggcga cgcatcatac caagaggagt
    12601 ctgcgtatcg acgttaatga caccagcgcc atgacagcgt ccacaagtga ctggacttgt
    12661 ccctggctta gcaccagagc cattacatgt acgacagcca gcttcacgat gatacttaac
    12721 ttccttctca gttccgaaga tagcttcttc aaaggtcaaa ttgacacgat actggagatc
    12781 atctccttgg cgaggagcgt ttggattgcg cgaagaaccg cctccgccga agaaacttga
    12841 aaaaatatcc tcaaaaccac cgaagccacc tgccccattg aaaccaccga aaccaccagc
    12901 tccaccaaaa ccaccattgg cgcctgcagc accatactgg tcataggcag cacgtttttg
    12961 gtcgtcactc aaagtctcat aggcttcttg aacttccttg tacttgtcct cagcaccagg
    13021 ctccttgttg atatctgggt gatatttttt ggaaagctta cgataagcct ttttgatctc
    13081 gtctgccgaa gcgttttttg acacccccag acgatcataa aattcagtat tgttcataca
    13141 agataccaag accgtaaaat tcgactgaaa aataggaaat ctgacgctgg agcgacgctc
    13201 ctagacagat ttctcttttt tccgagaatt taggtcgggt tcaattcctt tcttttatat
    13261 tgatgagata atactccagc cactcggccc tatccctttt taccgaaaaa cagaggctga
    13321 gttgcaacct ctgtggttag attattcatt tgaaataaaa atggttgtat tatctctagt
    13381 agtaatcttc aaagaccttt tagctaaatc aaactcaaat ttattatagt gtgggtcttg
    13441 tgttttatat aggtgtaact cctgacatat atgatccgaa aagtaaatca taacatcttt
    13501 aaacacagaa gtgtggtcat atttactctt accaacagct acttctgtaa attctttata
    13561 aatgacattt ccatttcttt ccacagtcac cagcatttct gttggattat aatccaaatt
    13621 aaataattct tcaaaaaact ttatcttttc atgataatct gcaatgtcag aaagattatt
    13681 tttattaaca ctcataacac tagcccctta tttttcagta aactctccgt ctacgacgtc
    13741 atcgcctgcg tttcctgttg cttgtgcgcc ttctgctcct tcttgagctt gttgcgctgc
    13801 tgcagcttgt tcgtagagtt taacagcaag tccttgagct ttttcgttca atgcttcaag
    13861 ttttgctttc atgtcgtcca agttgttgtc ttcttgagct ttcttaaggt catcaagggc
    13921 agcttgggca gcgtcacgtt ctgcgtcgaa gcctttacct tcagtttcct tgattgtctt
    13981 ttcagtcgca aagattgctt ggtctacttc attacgaagg tctacttctt ctttacgttt
    14041 cttatcggct tcagcgtttg cttctgcatc tttcatcatg cggtcgattt cttcgtcagt
    14101 caaacctgag ttcgattgga tgacaatagt ttgttctttt tgagttccaa ggtctttggc
    14161 cttaacagac acgataccgt tcttgtcgat gtcaaatgtt acttcgattt gaggaattcc
    14221 acgaggtgca gctgggatat cagtcaattg gaagcgtcca agagtcttgt tatctgctgc
    14281 cattgggcgt tcaccttgaa gaacgtggat atcaacggct ggttggttgt ctgctgctgt
    14341 tgagaagact tgtgatttag atgttgggat tgtagtgttg cgatcgataa gttttgtaaa
    14401 tactccaccc attgtttcga taccaagtga caatggcgtt acatcaagaa ggacaacgtc
    14461 cttgacatca ccagtaatca caccaccttg gatagccgca cccatagcaa ctacttcatc
    14521 agggtttact gatttgtttg gttctttacc agtttcagct ttaacagctt caacaacggc
    14581 agggatacga gttgaaccac caacaaggat aacttcgtcg atttctgaca agctcaaacc
    14641 tgcatctgaa agggcttgac gaactggaac ttttgtacgt tcaacaaggt cacgagtcaa
    14701 atcgtcaaat ttcgcacgag tcaaagtcat ttccaagtga agaggtccag cctcacctgc
    14761 agtgataaat ggcaagctga tttgtgttga agttacacca gaaaggtctt tcttcgcttt
    14821 ttcagccgca tctttcaaac gttgcattgc catcttgtca gtagacaagt cgataccgtt
    14881 ttctttcttg aattctgcta ccaagtggtc aatgattttt tggtcaaagt cgtcaccacc
    14941 aagtttgttg tcccctgcag ttgacaatac gtcgaagaca ccgtcaccca attcaaggat
    15001 agagacgtcg aatgtaccac caccaaggtc aaataccaag attttttctt ctttgtcagt
    15061 cttgtccaaa ccataagcaa gagctgctgc agttggttcg ttaacaatac gttctacttc
    15121 aagaccagca attttaccag cgtcttttgt tgcttgacgt tgagcgtcgt tgaagtaagc
    15181 cggaactgtg ataacagctt tggttacttt ctcaccaagg tagtcttcag cgtagccttt
    15241 caagtattga aggatcatag ctgagatttc ttgtggagtg tattcttttc catttgcaga
    15301 aactttttca gaagttccca tcttagattt gatagagata actgtatctg ggtttgtaac
    15361 tgcttgacgt tttgcagcat caccaacgat gatttctccg tttttgaatg agactacaga
    15421 tggagttgtg cggtttcctt ctgggtttgc gatgattttg ctttcagttc cttcaagaac
    15481 tgcaactgct gagtttgttg tacctaagtc aataccgata attttagaca tgtgtttttc
    15541 tccttgttag ttaattttct atttttcttt ttgatactct tcttaagtgg cgacgccgtc
    15601 agagcttgac ttcgtcaatc tctttgacta aactttgagc ctaaggtctc aaaatttgcg
    15661 caaatagcac cacggcgaag agtatcgtct ttggttcgct tcgctcacta ttacaaagcc
    15721 aaacatattt tatctttctt catagtttat tgtcgtttcg gacaagtttt ctattatgta
    15781 aattgcgaca cgaggagtcg aaatcgattt tatttcgacg acgagttagt aaggaagcta
    15841 ggcaaacgtc atagcgattg ccgttttctg acgagttgct ttagctaccg tcagaattgc
    15901 cgaatcgaac acgccctaag ctctgagtaa aaaagataga ttttcttgtg ttcatcgaac
    15961 acttcgtcaa tctcctattt ttactgcgag ctttttacga gctttgtatc ttagttatac
    16021 accactacca ttgctgggcg taggatgcgg tcatggagtt tgtagccttt ttgaaagact
    16081 tgggcgatgg tatctactgg gtgttcatcg tctgctggga gagtttggat ggccatatgg
    16141 tagttatggt caaattcgcc atctgctgcg atttcttcaa ttccttcttc tttcaaagcg
    16201 tgaatcaagc tttcttgcac catccccaag cccttcttca catcatctgt caaaccttca
    16261 actgcaagtg cacgctcaag gttgtcaaga gatggtaaga ttgcttttgc caagtcctgg
    16321 ctacgataac gttgcaagtt ttgacgttct tcattggcac ggcgttggat attttgcatt
    16381 tctgcatgag cgcgaagata tttgttttcg aactcatctg cacgttcatt tgccaagtcc
    16441 aactcagact tttcaggagt tgtttcttca gctgtttcca caacttcctc ttcttgaact
    16501 tcttctactt cttcattttt tatatcttgg gccatgttcg cctcctttaa tgatttcaat
    16561 cttaatgtac ttcgtaatga ttactgctga ggtagcggta aaaatctgtc aacttcatgg
    16621 tcaaaacacg gttgaccaca ttgacttgat tgattagctg ttggtaatcc agattaactg
    16681 gaccgataat ggctagaatt ccaactcccc gataaggaat gaggaactta ctactaatca
    16741 ccgctaggtc agctaaacag gactcttgac cgtctgcaac acgaacattt tgcatctgat
    16801 cctcacgcaa cccctcacga atctccaagg ccaccttttg cggttggtca aagaactgat
    16861 aggcttctag attggcaaaa ttcaagagat tgaccttgcc cgccatcaca atgttttcgt
    16921 tgaacatttc cttaaagatg tgttcaaaga gatcgatgac attatccgtt gttgtaaagt
    16981 aacgctggat aatctgcgga atctccgtcc gaatcttgta gtgaatatct aaaacggtgt
    17041 gaccgaggaa acgttcctga atgatgctct tcagtttcag caaatcctcc tgcaagaagt
    17101 tccttggaat cagaaactga ctagtaaccg ttcgcgactc gtctagggta aataccgcca
    17161 aggctgtatg ttgccccaaa acaacgatat caaaggctgt caaacgttgc ctgctcggct
    17221 caacatccag tgccactacc gtacagccac tcaggcctgt tagcaagtta gcagcctctt
    17281 gcagaatatc ctccaatttg aagaattcct gatcaaaggc tttgacaatc tcatatacct
    17341 cattttcagc cagccggtga aaatccagtg agtgtttcac atagtactga aaaccagcaa
    17401 cacttggcat ccgaccgctt gaagtatgag ccttctcaag caacccttgt ttttctagtt
    17461 ccgccatgtc attacgaatg gttgcactgc tagagttaat agactcttgc aaggcttttg
    17521 atccgacagg ttcgtgcgtt ttggtaaaga tgtcaataat cagatttaaa atatcctgct
    17581 gacgctctgt aaccatctca tcactcctct ctgtctgatc aattagcact caatgcatcc
    17641 aagtgctaac ttatgattct attatacacc cttaaaagag aatgtcaaga caaaaactca
    17701 aaaaattagc actcttttat caagagtgct aaaaatcaat ctgaagacct agaaccttgc
    17761 tattcatcta ctcggtattt cctttttagt ctgaaataac catgaattag ataagaaatc
    17821 agaaaagcat ataaaacaaa aataagaaag aaagacatag aaagatcctc tctaaacaaa
    17881 ctcgtacaaa caacaagacc acctaagaaa gtagttgtac aggaacgaag tctagatcgc
    17941 ataacttccc atttgagccc cttactcata tagacttgat cctctggaag taaatcagaa
    18001 gacgatttac gaagaatcga acaagaacct gctcctatca attcccaacc tctatctcta
    18061 aaatcttgca gttcatgctt atatttttta agaaatctag aatcatagat acggtagatg
    18121 acatcgtctg gttgacattg gtcaaaatag aacaaaccaa aacgactcgt tctatacctc
    18181 caacctttca aatgcatctc atgtaaatat tcttcttcct tgtccaaatc aacaatggtg
    18241 aaaatccgaa attctactct gctattcatt gtcttacccc aaaattagaa aacatgcctg
    18301 gcgttattta ttagataatt ctttccactt ttgactcaat ctccaaaaaa tataagaaat
    18361 ctgaatcgca aaaactatca ataaaaccca atctattatg aaaatcaaaa acactttcca
    18421 actgaaagaa ctacctccag tgacaaactt tgagcaaaac ggtagtagag ctaaaaagag
    18481 aagtaaaata ggaagcatcc gcattgttaa aatccgtttg gcataaaaaa atctttattt
    18541 aaactaaaat attatagcaa aatttacgcc agtttttgaa cggctgatgt agatatttta
    18601 tactttcaaa atgtttaaat gtgattattt atttttgaaa aatagctcac cagcccgact
    18661 gaaagtgctt atagaatgat aataagtcgc ctgccgaaaa cagcggaaaa tagcggtgtt
    18721 atgcggagat aatctgacgc gatgcgaaag tatattgcat acttattttc aacaatttag
    18781 cagagtattt ttataagtgt gatataatag aagtataatt tgttctgata gtttatttta
    18841 tggagaagta gatttttaga atgcggaggg ttcaatatgg ttgagtttat aaagtctaag
    18901 aaagaaatga gtgaggagga tattaaagca aatttcatca ctcctgctat tgtatccaaa
    18961 ggatggaaaa atggtgagca tatcgcttac gaagaatact tcactgatgg tcgaattgag
    19021 gttagaggag ataaggctcg tcgtaaagaa ggaaaaaaat cagactattc actgtattac
    19081 caatttggaa ctcgaattgc aattgttgag gcaaaggata ataaacacag cgttcgagca
    19141 ggattacaac aagctattga atatggagag attttagatg ttccatttgt ttattcttcg
    19201 aatggtgatg gctttattga acacgaccgt atcacgagag aagaacgtga gctggagtta
    19261 gacgaattcc ctactcgtga agaattattt tctcgtatga cgaaggaaaa aggattgacg
    19321 tacgaaatta cagaagctat ctcaactcca tactatacag acgccttctc aatgaaaacg
    19381 ccacgctatt atcagcaaat agctatcaac cgtactattg aaacagttgc cagaggacaa
    19441 aaacgagtaa tgtttgtgat ggcaacagga acagggaaaa cgttcatggc ttttcaaatt
    19501 attcatcgcc ttcgaaaagc tggtttggct aaacgagttt tattcttagc agatagaaac
    19561 atcttagtag accaaacgat ggctgaagac tttaagccat tcgaaaaggt aatgacgaaa
    19621 attacaccaa aacttttgac tgctcctgaa aaattaaatt ctttcgaaat ttatctaggg
    19681 ctttatcagc aactaactgg tgaagatgga actgaaacac attatcaaaa atttgacaaa
    19741 gacttctttg atttaatcgt aattgatgaa gcgcaccgtg gttcagctaa ggaaaacagt
    19801 aactggcgta aggtaattga ttatttcagt tctgcgacac agattgggat gaccgctact
    19861 cctaaagaaa ccaagaatgc ttccaatacg gaatactttg gtaagccaat ctatacttat
    19921 agtttaaaac agggaatcga ggatggtttt ttggctccat atcgtgttat gagggttaat
    19981 ttagatgtgg atgtggatgg ttatcgtcca gaaactggaa aagttgatgc taacggacaa
    20041 ttaatagaag ataggtacta cggcaggaaa gattttgata aaaccattgt cattgatgat
    20101 agaacgcaaa gagttgccaa gtttgtttct gattatatga agcaaaacaa tgcacgattt
    20161 gataaaacaa ttgttttttg tgttgatatt gaccatgccg agcgaatgcg tgctgcactt
    20221 gtaaaagaga atctagactt agtccaagaa gactatcgtt atgtcatgca agtaactggt
    20281 gacaacgctg aaggaaaagc tcaactggat aactttatgg atgtcaattc taattttccc
    20341 gctattgtaa caacgtctaa attattaacg acaggagtta atgctaaaac atgtcgtttg
    20401 attgttttag actctaatat ccaatccatg actgaattta aacaaattat tggtcgtggc
    20461 acacgtcttt atcctcaaaa ggggaaagaa ttttttacga ttattgattt tcgaaatgtt
    20521 accaatttgt ttgctgaccc tgattttgat ggtgagccag tgaaggtgct ggaaacaggt
    20581 gcgaaaacag tcagtggttc tacgcctggt ttcgtaggtg aggaaggtga cccagtagaa
    20641 aaatatatcg ttacagacaa gcaggttacc attcttaatt ctactgttca agtattggat
    20701 gaaaacggga aactgattac cgaaagcctg accgactaca ctcgaaagaa tatcttaggt
    20761 agctacgcca ctttgaacga ttttatcaca gtttggcata cggcagataa gaaacattat
    20821 gggaagtttg ctgatggaag cactcaagaa attgatgttc cttatgatat tcctgatact
    20881 tgggagtggg tgaggttttc tacattggtt gaaattgtca gaggtggctc tccacgacca
    20941 atcaaagatt atcttacttc tgaagtagat ggaataaatt ggataaaaat aggtgatact
    21001 gaaaagggtg aaaagtatat aaataatgtt aaagaaaaaa tcaaaaaatc agggcttaac
    21061 aaaactagat ttgtaaaaaa aggtacattt ttgttaacta attctatgag ttttggtaga
    21121 ccttatattt tgaatgttga tggtgcaata cacgatggat ggttggctat ttcgaactat
    21181 gaaaactcat taaataaaga ttacctattc tatattcttt catcaaatgt agtttattct
    21241 caatttctat ctctaattag tggagctgtt gtgaaaaact tgaatagtga taaagttgct
    21301 tctattctta tc
//
LOCUS       DAVAZT010000040        21102 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVAZT010000040 DAVAZT010000000
VERSION     DAVAZT010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21102)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21102)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21102
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.040"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..266
                     /locus_tag="VQT45_001415"
     CDS             <1..266
                     /locus_tag="VQT45_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HET2359728.1"
                     /translation="SIDERLRTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGW
                     GDHYQLVAQKSVLKRAISKPVLEKRGLVSCLDYYLERHALKVS"
     gene            720..1413
                     /locus_tag="VQT45_001416"
                     /pseudo
     CDS             720..1413
                     /locus_tag="VQT45_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809626.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            1469..1741
                     /locus_tag="VQT45_001417"
     CDS             1469..1741
                     /locus_tag="VQT45_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase"
                     /protein_id="HET2359729.1"
                     /translation="MFLLFSALVGMLSQLKEVPESVFLQETVEENHLVNVYSVLEVIS
                     TLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK"
     gene            2055..2186
                     /locus_tag="VQT45_001418"
     CDS             2055..2186
                     /locus_tag="VQT45_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HET2359730.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            2207..3757
                     /gene="dltA"
                     /locus_tag="VQT45_001419"
     CDS             2207..3757
                     /gene="dltA"
                     /locus_tag="VQT45_001419"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HET2359731.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFVQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMIMDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGVTHFYFDG
                     EELTVKTAQKLRKRFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            3754..4998
                     /gene="dltB"
                     /locus_tag="VQT45_001420"
     CDS             3754..4998
                     /gene="dltB"
                     /locus_tag="VQT45_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HET2359732.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            5012..5251
                     /gene="dltC"
                     /locus_tag="VQT45_001421"
     CDS             5012..5251
                     /gene="dltC"
                     /locus_tag="VQT45_001421"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HET2359733.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            5244..6512
                     /gene="dltD"
                     /locus_tag="VQT45_001422"
     CDS             5244..6512
                     /gene="dltD"
                     /locus_tag="VQT45_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HET2359734.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            6667..7107
                     /gene="adcR"
                     /locus_tag="VQT45_001423"
     CDS             6667..7107
                     /gene="adcR"
                     /locus_tag="VQT45_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HET2359735.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            7107..7811
                     /locus_tag="VQT45_001424"
     CDS             7107..7811
                     /locus_tag="VQT45_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET2359736.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNTHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            7804..8610
                     /locus_tag="VQT45_001425"
     CDS             7804..8610
                     /locus_tag="VQT45_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET2359737.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGRSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            8620..10125
                     /gene="adcA"
                     /locus_tag="VQT45_001426"
     CDS             8620..10125
                     /gene="adcA"
                     /locus_tag="VQT45_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HET2359738.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKVTFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(11245..12018)
                     /locus_tag="VQT45_001427"
     CDS             complement(11245..12018)
                     /locus_tag="VQT45_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2359739.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTLPDQKLLDAVELFDGEWVSDIQ"
     gene            12194..13597
                     /locus_tag="VQT45_001428"
     CDS             12194..13597
                     /locus_tag="VQT45_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HET2359740.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEATAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            13712..14350
                     /locus_tag="VQT45_001429"
     CDS             13712..14350
                     /locus_tag="VQT45_001429"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HET2359741.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            14362..14802
                     /locus_tag="VQT45_001430"
     CDS             14362..14802
                     /locus_tag="VQT45_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HET2359742.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            14795..15226
                     /locus_tag="VQT45_001431"
     CDS             14795..15226
                     /locus_tag="VQT45_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2359743.1"
                     /translation="MFNRGILVASHGDFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVDELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISNYDSKINLEEIVHNAQNSLFNVKQQLNVEEEENLCL"
     gene            15217..15687
                     /locus_tag="VQT45_001432"
     CDS             15217..15687
                     /locus_tag="VQT45_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2359744.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            15712..16485
                     /locus_tag="VQT45_001433"
     CDS             15712..16485
                     /locus_tag="VQT45_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET2359745.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            16482..17282
                     /locus_tag="VQT45_001434"
     CDS             16482..17282
                     /locus_tag="VQT45_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2359746.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            17341..19635
                     /locus_tag="VQT45_001435"
     CDS             17341..19635
                     /locus_tag="VQT45_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET2359747.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPVNLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            19645..>21102
                     /locus_tag="VQT45_001436"
     CDS             19645..>21102
                     /locus_tag="VQT45_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359748.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLH"
BASE COUNT         6542 a         3448 c         4467 g         6645 t
ORIGIN      
        1 ccagcataga tgagcgcttg cgtactcgcc tacgagtgat tatctggaag caatggaaga
       61 agaaatcgag acgattatgg ggattgctta agttaggagt tcctaaatgg atagcagata
      121 aggtatctgg ctggggcgac cattatcaat tagtagctca gaagtcggta cttaaacgtg
      181 ctatatcaaa accagtcctg gaaaaacgtg gactggtttc gtgtttggat tattaccttg
      241 aacgacatgc gttaaaagtt agttgaaccg ccgtatgccg aacggcacgt acggtggtgt
      301 gagaggggct agagattatc ctctactcga ttaactcccc tgaaatttgt tttaattatg
      361 caaatttcac gtatttttga tgctgagacg acgatcctgg gaacttttca gatatttttt
      421 tgactatcta aaatctatca ttagaaaagc ttagagcgcc aaaggatttg agcgtttttc
      481 tgatttttaa gactttttcc cagtctcttt ttcgattgaa gatgtaatta ttctactaac
      541 taacttctta gtactagcca acaacgataa tcataattcc tcctaaaatt aggaataata
      601 aaggcaatag tttttgtttt ttcatgtaaa aaacctcact tttgttttct gctattttat
      661 gctaaaatat taaaaatcaa atttaattcc aaagtttgta actaaagggg gagcgctaca
      721 tgtctaattc atttgtcaag ttgttagtct ctcaattatt tgcaaattta gcagatattt
      781 tctttagagt aacaatcatt gctaacatat acattatttc aaaatcagta attgccacat
      841 cactagttcc tatcttaata ggaatatcct cttttgttgc gagtctttta gttccgttgg
      901 ttactaaaag gttagcgcta aatagggttt tatctttatc tcaatttgga aagactatat
      961 tattggcgat actggtagga atgtttaccg taatgcaatc cgtagcgcct ttggtgacct
     1021 atctatttgt tgttgcaatt tccatactag atggttttgc agcacccgtt tcctatgcta
     1081 ttgtgccacg ctatgcgacc gatttgggta aggctaattc agccttatca atgactggtg
     1141 aagctgttca attgataggt tggggattag gtggactctt gtttgcaaca attggtctgt
     1201 tacctaccac gtttatcatt ttagtcttgt atatcatttc tagctttctg atgttatttc
     1261 ttcctaacgc tgaagtggag gtgttagagt cagaaactaa tcttgaaatt ttgctcaaag
     1321 gttggaagtt agttgctaga aatcctagat taagactttt tgtatcagca aatttattgg
     1381 aaattttttc aaatacgatt tgggtttctt ccattttgta gctatggcaa tagtgacact
     1441 gactattcta tattttccaa acgcacagat gtttttatta ttttcagctt tagttggtat
     1501 gttatcgcaa ctaaaagaag ttcctgaaag tgtatttctt caggaaacag tagaggaaaa
     1561 tcatttagtt aatgtctatt ccgttcttga agtgatttct acattagcat tttcagtatt
     1621 tgttttgcta atgagctata ttactgagag ttttggtatt agcatcagtt tttggctatc
     1681 agccatttgt ctgatgatag aagctatttt aatttatatc agacgagatt attttaaatg
     1741 agagagtggt taaaaagtct ttaaaaatca gaaaagcgca tagtatcagg tgttgaaaaa
     1801 acttgatatt gtgtgtttta ttatgggaag atttacttca ttgtctcctg aaatggagtt
     1861 ttgaagcagg atcactctat ttgaaaatat acatagaaaa actgtataat ccttaaaata
     1921 agctgaaatc tattggaaac atacggtaaa caattgaaaa ggtactatat aaagtggtac
     1981 aatggtagaa aaataagcta gtaagaatca ctcttatttt agcgaaaaat tacagaaatg
     2041 aatggttttt cttgatgaaa cagagaaaag aattgtacct ctttcttggt cggacagcct
     2101 tgtattttct tatctttcta gggctgcttt acttctttag ctatcttggt cagggtcaag
     2161 gaagctttat ctataatgaa ttttaacttg aaggagaatc cctattgtgt caaataaacc
     2221 aatagcagat atgattgaaa ccattgagca ttttgctcag acacagccta gctatcctgt
     2281 ctataatgtt ttggggcagg aacacactta tggcgattta aaggctgatt cggatagttt
     2341 ggctgcagtc attgaccaac taggcttgcc tgagaagtct cctgtggttg tttttggtgg
     2401 ccaagaatat gaaatgttgg caacctttgt agcgctgact aagtcaggtc atgcctacat
     2461 tccaattgat agccattcgg ccttggagcg agtttcagct attttagaag tagcagagcc
     2521 aagcttgatt attgccattt cagcctttcc cttggagcag gtttctacac caatgataaa
     2581 tctagctcag gttcaagaag cctttgttca agggaataac tatgaaatca cgcatccagt
     2641 caagggagat gataattact acattatctt tacttctggt acgactggta agcctaaggg
     2701 agtgcagatt tcacatgata atctcctcag ctttacaaac tggatgatta tggataagga
     2761 atttgcgaca ccgagtcgtc cgcaaatgct ggcacagcca ccttattctt ttgacttgtc
     2821 tgtcatgtat tgggcaccga ccttggcact tggtggtacg cttttcactc ttccttcagt
     2881 catcactcag gactttaagc aactctttgc ggctatcttt tcattgccaa tcgctatctg
     2941 gacatcaaca ccatcctttg cagatatggc catgttgtct gaatacttca acagtgagaa
     3001 aatgcctgga gtcacgcatt tctactttga tggtgaagaa ttgacggtca aaacagctca
     3061 aaaactgcgc aagcgtttcc caaatgcccg tatcatcaat gcttacggcc caacagaagc
     3121 gacagtagct ctgtcagcag ttgccgtgac agacgagatg ttagcgactc tcaaacgcct
     3181 accaatcggc tataccaagg ctgattctcc aacctttatc attgacgagg aaggaaataa
     3241 actgccaaat ggcgaacagg gagaaatcat tgtttctggg ccagctgttt caaaaggtta
     3301 tatgaacaat cctgaaaaaa cagcagaagc cttctttgag tttgaaggtc tgccagccta
     3361 tcacacaggc gatgtgggaa ccatgacaga tgagggcttg cttctctacg gcggacgcat
     3421 ggacttccag attaagttta acggttaccg cattgagtta gaagatgtct ctcaaaacct
     3481 caacaagtct cgctttatcg aatctgctgt cgcagtaccg cgctataaca aggaccacaa
     3541 ggtacaaaat ctattggctt atgtcatctt aaaagacggt gttcgtgagc agtttgagcg
     3601 agatatcgat attaccaagg ccatcaagga agacctgaca gacatcatga tgtcctatat
     3661 gatgccatct aaattccttt accgagacag tttgccactg actccaaatg gaaagattga
     3721 catcaaagga ttgattaacg aggtgaataa gagatgatgg agttttttca acagcttcct
     3781 catttagagc catatggcaa tcctcagtat tttgtttatg tgattgctgc aaccttgccc
     3841 atctttatag gtctcttttt caagaaacgc tttgcctggt atgaagtgtt ggtaagtctc
     3901 ttctttattg tcaccatgtt ggtgggtgga aagaccaatc aactagctgc cttgggtatt
     3961 tacctttgct gggaaatatt gctcctgctt ttctacaagc attatcgaaa aagcaaggat
     4021 ggcaagtggg tcttctactt agttagtttt ctgtccctac ttccgattat ctttgtcaag
     4081 gtgcaaccag ctatcaatgg aacgcagtct ttgcttgggt tcttgggaat ttcttatctt
     4141 acctttcgtt cggttgggat tatcatcgag ctgagagatg gagtgattaa ggattttacc
     4201 ctctgggaat tcctccgttt ccttctcttc atgccaactt tctcgagtgg tccaatcgat
     4261 cgctttaagc gatttaatga aaattatcag gctattcctg agcgagatga gttgatggat
     4321 atgctggatg aatctgtccg ctatatcatg tggggctttt tgtataagtt tatcctagct
     4381 catgttttag gagagacctt actacctcct ctgaagaatt tagccttgca gtcaggtggc
     4441 ttctttaatc tctatgcctt ggcagttatg tatacttttg gtctggagct cttctttgac
     4501 tttgcaggtt attctatgtt tgctttggcc atctcaaact tgatgggaat ccgtagccct
     4561 atcaacttta acaagccctt tttatcaagg gatttaaagg agttttggaa tcgctggcat
     4621 atgagtctgt ccttctggtt ccgtgacttt gtctttatgc gaatggtgat ggtgttaacc
     4681 agaaagaaag tctttaaaaa tcgtaatgta acctcaagca tggcctacat tgtaaatatg
     4741 ctgattatgg gattttggca tggtgtgacc tggtactata tcgcctatgg actctttcat
     4801 ggactaggct tggtcatcaa tgatgcctgg gttcgcaaga aaaaaacact caataaggaa
     4861 cggaaaaaag cagggaaggc tgccctacct gagaatcgct ggattcagtt gcttggcatg
     4921 gttgtcactt tccatgttgt catgttgtca ttcttaatct tttctggatt cttgaataat
     4981 ctatggttta aaaaataaaa ggaaataaaa tatggatatc aaatcagaag ttatcgaaat
     5041 tattgatgag ttgtttatgg aagatgtttc tgacatgatg gatgaagatc tttttgatgc
     5101 aggtgtcttg gatagtatgg gaacggttga gttgattgtg gagattgaga accgttttga
     5161 cattcgtgtc cctgtaacag agtttggtcg tgacgactgg aatacagcta ataaaatcat
     5221 agctggtatt gtggagctac aaaatgctta aacgcttatg gatgatcttc ggaccggtct
     5281 tgatcgctgg tttgttggtt tttctgctca ttttctttta tcctactgag atgcatcata
     5341 atctaggagc tgaaaagcgt tcagcagtgg ctactactat cgatagtttt aaggagcgaa
     5401 gtcaaaaagt cagagcacta tctgatccaa atgtgcgttt tgttcccttc tttggctcta
     5461 gtgaatggct tcgttttgac ggtgctcatc ctgcggtatt agctgagaaa tacaatcgtt
     5521 cctaccgtcc ttatctttta ggacaggggg gagctgcatc gcttaaccaa tattttggaa
     5581 tgcaacagat gttaccacag ctggagaata aacaagttgt gtatgttatc tcacctcagt
     5641 ggttcagtaa aaatggctat gatccagcag ccttccagca gtattttaat ggagaccagt
     5701 tgactagttt tctgaaacat caatctgggg atcaggctag tcaatatgca gcgactcgct
     5761 tactgcaaca gttcccaaac gtagctatga aggacctggt tcagaagttg gcaagtaaag
     5821 aagaattgtc gacagcagac aatgaaatga ttgaattatt ggctcgtttt aatgaacgcc
     5881 aagcttcctt ttttggtcag ttttcggtta gaggctatgt taactacgat aagcatgtag
     5941 ctaagtattt aaaaatcttg ccagaccagt tttcttatca ggcaatagaa gatgttgtca
     6001 aagcagatgc tgaaaaaaat acttccaata atgagatggg aatggaaaat tatttctata
     6061 atgagcagat caagaaggat ttgaagaaat taaaggattc tcagaaaagc tttacctatc
     6121 tcaagtcgcc agagtataat gacttgcagt tggttttaac acagttttct aaatctaagg
     6181 taaacccgat ttttatcatt ccacctgtta ataaaaaatg gatggactat gctggtctac
     6241 gagaggatat gtaccaacaa acggtgcaga agattcgcta ccagttagaa agtcaaggtt
     6301 ttaccaatat agcagatttt tctaaggacg gcggggagcc tttctttatg aaggacacca
     6361 ttcaccttgg ttggttgggt tggttggctt ttgacaaggc agttgatcct ttcctatcca
     6421 atcccacacc agctccgact taccatctga atgagcgctt tttcagcaaa gattgggcga
     6481 cttatgatgg agatgtcaaa gaatttcaat agataatata atatagaaga gttcaagaat
     6541 gaaactagtt ttcacgtttt ttcttgactc tttttttgct tgtgatataa ttaactggta
     6601 aacaaaatgt caaagaatag tatttttctc ttaaaaaaga gaagtctaaa aggaaaggag
     6661 tcagatatga gacagctagc aaaggatatc aatgcttttt tgaatgaggt gattttgcag
     6721 gcggaaaatc agcatgaaat cctaataggt cattgcacta gcgaggtggc cctgaccaat
     6781 actcaggagc atatccttat gctcttgtca gaggaatctt taacaaattc agaattggcc
     6841 cgtcgtctca atgtcagtca ggcggcagtt accaaggcca ttaagtcttt ggtcaaggaa
     6901 gggatgttgg aaacatctaa agattctaaa gatgcgcgtg tgatttttta tcagttgact
     6961 gacttggctc gtccaatcgc tgaggagcac caccatcacc atgagcatac acttttaacc
     7021 tatgaacaag tggcgactca gtttactcca aatgaacaaa aagtgattca gcggtttttg
     7081 actgctttag taggagaaat caaataatga gatatattac ggtagaggat ttgtccttct
     7141 attatgataa ggaacctgtt cttgaacata tcaattattg tgttgatagt ggggaatttg
     7201 ttaccttgac tggggaaaat ggagcggcta agacgacgct catcaaggcc agtcttggaa
     7261 ttctgcaacc acgcattgga aaggtggcta tttcaaagac aaatacgcaa ggtaagaaat
     7321 tgagaatagc ctatcttcct caacaaattg ccagttttaa tgctggtttt ccaagtacgg
     7381 tctatgaatt tgtcaagtcg ggtcgctatc cgagaaaagg ctggttccgt cgtttgaata
     7441 ctcatgatga ggagcatatc aaggctagtc tggactcagt tggcatgtgg gaacatcgag
     7501 acaaacgctt ggggtctcta tctgggggac aaaagcagcg agcggtaatt gcgcgtatgt
     7561 ttgcttctga ccctgatgtg tttatcctag acgagccgac aacggggatg gatgcaggaa
     7621 gtaaaaatga attttacgaa ctcatgcacc acagcgccca tcatcatggc aaggctgttt
     7681 tgatgattac ccatgaccct gaagaagtta aggattatgc ggatcgcaat attcatctag
     7741 tccgtaacca agactcgcca tggcgttgtt tcaacgttca tgagaatggg caggaggtgg
     7801 gccatgctta gtttattatc ttacgacttt atacaacgcg cctttttggc ggttattgct
     7861 atgagtcttt tctcaccggt attgggaacc ttcctcatct tgcgtcgtca gagtttgatg
     7921 agtgataccc ttagccacgt ctcactttca ggtgtagcct ttggtctggt tttggggatt
     7981 tctccaactg tttctactat tgccattgtc ttgattgcgg cggtctttct ggagtatctc
     8041 cgtacggttt acaagagctt tatggaaatc gggacagcta tcctcatgtc aacaggtttg
     8101 gctgtttctc tgattgtcat gagcaagggt agaagctcga gttcaatgag tttggaccaa
     8161 tatctctttg gttcgatcgt gactatcagt gaagaacagg tcatttccct ctttgtcatt
     8221 gcggcggttg ttttgatttt gacctttctc tttcttcgtc ctatgtatat cttaactttt
     8281 gacgaagata cggcctttgt ggatggcttg ccagttcgta ccatgtccat tctttttaac
     8341 atggtgacag gggtggctat tgcccttatg attcctgcag caggagctct tctggtatcg
     8401 accattatgg tcttgccagc tagtattgcc ctgcgtctgg ggaaaaactt taaatcggtt
     8461 atgctgcttg ccagtgcgat tggctttttg ggaatggtag caggacttta catttcctac
     8521 tatgcagaaa cacctgcaag tgcaagtatt accattattt ttgtaactgt ctttatacta
     8581 atcagtttag taagacgttt tatcaaatag gagacgaacg tgaaaaaaat tagcttatta
     8641 ctagccagtc tatgtgcctt gtttttagtg gcttgttcca atcaaaaaca ggcagatggt
     8701 aaactcaata tcgtgacaac cttttaccct gtctatgaat ttaccaagca agtcgcagga
     8761 gatacggcta atgtagaact cctaatcggt gctgggacag aacctcatga atacgaacca
     8821 tctgccaagg cagttgccaa aatccaagat gcagatacct tcgtttatga aaatgaaaac
     8881 atggaaacat gggtacctaa attgctagat accttggata agaaaaaagt gaaaaccatc
     8941 aaggcgacag gcgatatgtt gctcttgcca ggtggcgagg aagaagaggg agaccatgac
     9001 catggagaag aaggtcatca ccatgagttt gacccccatg tttggttatc accagttcgt
     9061 gccattaaac tagtagagca catccgcgac agcttgtcag cagattatcc tgataaaaaa
     9121 gtgacctttg agaagaatgc agctgcctat atcgaaaaat tgcaagcctt ggataaggct
     9181 tacgcagaag gcttgtctca agcaaaacaa aagagctttg tgactcaaca cgcagccttt
     9241 aactatcttg ccttggacta tggactcaaa caagtcgcaa tctcaggact ttctccagat
     9301 gcagagccat cagctgctcg cttggcagaa ttgacagagt atgtcaagaa aaataaaatc
     9361 gcctatatct attttgaaga aaatgcctca caagcccttg ctaacacact ttcaaaagaa
     9421 gcaggtgtca aaactgatgt cctcaatcct ttagaaagtc tgacagaaga ggacaccaag
     9481 gctggagaaa actacatttc cgtgatggag aaaaacctca aggctttgaa acaaacaaca
     9541 gaccaagaag gcccagcaat cgaacctgaa aaggcagagg ataccaagac agtccaaaat
     9601 ggttacttcg aggatgcagc tgtcaaggac cgcaccttga gtgactatgc aggtaactgg
     9661 caatcagttt atcctttcct tgaagacggc acgtttgacc aagtctttga ctacaaggct
     9721 aagttgactg gtaagatgac ccaggctgag tacaaggctt actatacaaa aggctatcag
     9781 acagatgtga ctaagattaa cattactgat aatactatgg aatttgttca aggtggacaa
     9841 agcaagaaat acacttacaa gtatgtcggt aagaaaattt tgacttacaa gaaaggcaat
     9901 cgtggcgtgc gtttcctctt tgaagccaca gatgctgacg ctggacaatt caagtatgtt
     9961 cagtttagtg atcacaatgt tgccccagtt aaggcagaac atttccatat cttctttgga
    10021 ggcacaagcc aagaagccct ctttgaagaa atggacaact ggccaaccta ctacccagat
    10081 aacctatctg gccaagaaat cgcccaagaa atgttggcgc attgatgaga aatcgactag
    10141 ttcataagag ctagtcggtt ttttgatact agatggctaa cttcattata gacctttcag
    10201 aactttaaac aataaataaa actcttgaaa tatctgggct tatatgctag aatgtagtta
    10261 gtgtataagg ttcattagaa caccaaagcc cctaactagt gccatagtta agggcttttt
    10321 tgacgtatct tagcgattta acgggtgttt ataggctagt cagtcggtct acttcttacc
    10381 atctagccat ttgcagacga aatacaagat aattccagct ataacatctg ctataatagt
    10441 aagagcaagc tctggtataa ggctcattag tttcacctcc tctcacgaac ccataggaac
    10501 gtaatcggta accgatgaca aaaatagtat accacactaa atttagatca tcaacctcac
    10561 ttaatgcttg aactattgta gattatatgc taaaatgtag ttaattgata aggttcatta
    10621 gaacaccaaa gcccctaact atggccgtag ttaagggctt ttttgacgta tcttagcgat
    10681 ttaacgggtg tttataggct agtcactcgg tctactcctt actatctagc catctgcaga
    10741 cgaaatacaa gataattcca gctataacat ccgctataat agtaagagcg agctctatga
    10801 taaggctcat tagtttcacc tcctctcacg aacccatagg aacgtaatcg gtaaccgatg
    10861 acaaaaatag tataccacaa tatatttaga tcatcaaggt cacttaattc ttgaaatata
    10921 gggtctaggc gacaaagtct ttaaaatcag aaaaacgcat aatatcaggt gtgcaaaaac
    10981 ttgatactat gcgttttatt gtgggaaggt ttactccatt ttctcctgaa attgagtttt
    11041 tgtccagcct ctgtttttag aattgctaag aaaataatgt catgtggtga atatttgtaa
    11101 atcagtcagc agacagaacg aatactcttc gaaaatctct tcacatcatg tcagcttcgt
    11161 cttgccgtgt ccatggggga cttgacttga tcagttttca aatctgtact ttgagcaagc
    11221 tgagactagc ttcctatttg attttcattg aatatcagaa acccattctc catcaaataa
    11281 ttcgactgcg tctaataatt tttggtctgg caaggtgtca gaaataaagg ttgtgtattt
    11341 ggagagggga ttaattttaa aaaatccagt cttgtaaaat ttagaactat caatcagtaa
    11401 gatggtttca tgggctttgt caataatatt cttttttgaa atagcttggc tgagagaagc
    11461 ttcataaaca tattggtcat caatacctct tgctgaacaa aatgctaaat cgatattaaa
    11521 atgatctaat aaagaatttt ccttatcata gttgaccacg gaacaggatt gatgtttgac
    11581 ctcgccagat gtgataaaga ttttggagct atctttaaca gtttcagata gggtttgtgc
    11641 agtatgtaaa ccatttgtaa aaataatcaa attatcaagt tcagaaagat agggacaaag
    11701 ttcgtagaca gtagtactag aatctagata gatacacata ccagaccgaa taaagtcttt
    11761 agcgagacta gcgattagtc ttttttgcct agtactttct ccttcccgta tttgatgaga
    11821 aagttcaatt gtgttcatag aggacagggt cacgtatccg tgctttcttt tgataagacc
    11881 ttgattttct aagaaaatta aatcacgacg taaggtactt gtgctggaga aagtgatttc
    11941 tgccagctct tttacggcaa ttcttttttt ctttttaata atttcaatca attcaagtac
    12001 acgttcatct tttatcataa gctcctccta atttatcatt tcaactatat tatagcacaa
    12061 attggaggaa tttgaattat ttttatgaat attgggttaa catttgaaca ttattcaagt
    12121 aagcgttcac atattgaaaa aataaaacgt ggggattata ataaagttaa tcaaggacga
    12181 agagagaaga aaaatggaag cggttttagc aatagattta ggtgcgactt ctggaagagc
    12241 aatcgttggt tacctttctg aaaataaact agtaatggaa gaaataaatc gcttttctaa
    12301 tctacctatt agagtaaaag ggcatttatc ttgggatatt gactttctac tagctaaaat
    12361 tcttgaaagt atccgcttgg ctaatactag ttacaagatt ttatctatcg gtattgacac
    12421 atggggagtt gattttggac tgattgataa tgaaggtaag ctgttatcac aacctgttca
    12481 ttatcgtgat gaaagaacaa agggagtgtt aaaggaaata tctgaaatga ctgaattaga
    12541 aaaactgtat tcagagacag gaaatcagat tatggagata aataccttgt ttcaactctt
    12601 taaggcacgt caagaatctc ctgactcttt ctataagacc aataagattc ttttaatgcc
    12661 agatttgttt aattatctct tgacaggtaa gtttgctaca gaaaaaagca ttgcttcaac
    12721 aactcaatta tttgatccta ggagtcaaaa ttggaatcag aatatcttaa aactatttga
    12781 attggattca tctttacttc ctgaaattgt ttcagaggga aatgttcttg gaaggataaa
    12841 aaaggagtat ggtttaggcg atattcctgt tgtgaatgtt tgtagtcatg atacagcaag
    12901 tgcgattgtc tcagtaccta agacagaagg tagtttattt atttcatcag gtacttggtc
    12961 tttggttgga gtggaactta cttcaccgat tcttactacc gaatccttca gttatggatt
    13021 tacaaatgaa gtcggtaaag atggagtgat tacatttctg aagaattgta cagggttgtg
    13081 gatcatagag gaactaagac gttcatttga acgaagaggg aaagcctatt cttttgatga
    13141 tattaggaca atggtggaga aagaaaaaga aaatcttcct ctgattgata ctgaatcaac
    13201 tgaatttgca acagaatctg atatgcacaa gactttgaca gaatatctag cttatcatca
    13261 tgaaactaga gagtggacag atggacaact atttaagatt gtttatgaaa gcctagctga
    13321 aacgtatagg aaagcgatag agttattaga agaactaact cataaggttt ataagaggat
    13381 atatgtgatt ggaggaggtg ctagagccag ttattttaac caaatgattg ctgatagaac
    13441 tggtaaagag gttcttacag gtttgactga ggctacagct gtggggaata ttgttgtgca
    13501 gctcatagct atgggacaat taaaagggat ggaagaggct caccatgtta ttgaggagtt
    13561 tctacaatta gagagttatt actcccaaaa gaattaaaaa gattgagagt ttgtaaattt
    13621 gcctccctcc cccttcttag cttttgtgca ggaagggggg ataattggtg aattgaaaaa
    13681 tatttagtgt tttgatatga ggaggacaag gatgtcagat gtaaaacaag aattaattaa
    13741 atatggtaag aagctagtag aaacagattt gacgaaagga acaggtggga atctcagcgt
    13801 tttcgatcgt gaaaaacaat tgatggcaat taccccgtcg ggtattgatt tctttgaaat
    13861 caaagaatcc gatattgtag tgatggatat taatggaaat gttgtagagg gagaacgctt
    13921 gccatctagc gaatggtata tgcatttgat tcaatatcaa actcgtgatg atatcgatgc
    13981 aattatccat gctcatacaa cttatgcaac agtattagct tgtctcagag aaccacttcc
    14041 agcgagtcat tatatgattg cagtggcagg gaaagatgtt cgggtagctg agtatgcaac
    14101 atatggcacg aaagaattgg ctgtgaatgc agctaaagca atggaaggtc gtagagcagt
    14161 tttactagcg aatcatggaa ttttagcagg tgcacaaaat ttattgaatg catttaatat
    14221 tgttgaagaa gttgaatatt gtgcaaaaat ttattgttta gctaagaatt ttggagagcc
    14281 agtagttctt cctgatgagg agatggaatt gatggcagaa aaatttaaaa catacggtca
    14341 gagaaaatag ggaggatatt aatgttaaaa catataccga aaaatatttc tccagattta
    14401 ttgaagactt taatggaaat gggacatgga gatgaaatag tattagctga cgcgaattat
    14461 ccttctgcct catgtgcaaa taagctaatt cgttgtgatg gcgtaaatat tccagaatta
    14521 ttagattcca ttctgtattt aatgccatta gatagttacg tcgatagttc aattcagttt
    14581 atgaacgttg tttcgggtga tgatattcct aagatatggg gtacctatag acagatgatt
    14641 gaaggtcatg gtacagatct taaaacgatt acttatctta gaagagaaga cttttatgaa
    14701 cgtagtaaga aagcttatgc tattgttgct acaggagaaa cttcacttta tgctaatatt
    14761 atccttaaga aaggagtagt tgttgaaaga gaaaatgttt aatagaggaa ttttagttgc
    14821 cagtcatggt gattttgcta gcggagctct catgaccgca gaaatgtttg ttggtgagac
    14881 aacaaatgat agagttagga cattaggttt gatgcctgga gagaatattg tagagtttga
    14941 gcattatttt aaaaatcaag tggatgaact gttagactca aatcaagagg ttatcgtttt
    15001 gactgacttg attggaggaa gtcctaataa tgtggctttg tcacggtttt taaatttgga
    15061 ttcagttgat attgtaacag ggtttaatat tcctctccta gtggaattaa tatcaaatta
    15121 tgattcaaaa atcaatttag aagaaattgt tcacaatgct caaaatagtt tgtttaatgt
    15181 taaacaacaa cttaacgtag aggaggaaga aaatttatgt ctatagagtt tgttcgtatt
    15241 gatgaccgtc tggtacatgg tcaagttgtc actacgtggc taaaaaagta tgatattgag
    15301 caagttatca ttgttaatga tcgcatctca gaagataaaa cacgacaatc tattttaaag
    15361 atttctgcac cagtaggttt aaaaattgtt ttctttagtg taaaacggtt tgtggaagtt
    15421 ttaaactctg tgccaataaa aaagagaaca atgctgatat atacaaatcc aaaagatgtg
    15481 tatgattcta ttgaaggaaa tttaaaattg gagtacctca atgtaggaca gatgagtaaa
    15541 acggaggaaa atgaaaaggt aacgggaggt gtagctctag gtgaagaaga caaatattat
    15601 tttaagaaaa tagttgataa gggaacgaga gttgaaattc aaatggttcc taatgataaa
    15661 gttacaatgt tggaaaaatt tttataaaaa taatttaagg aggtacagta tatgctattc
    15721 acacaagcat tactggtgac attagttggg attattgcca ctattgacta taatggaccg
    15781 ttatttatga ttcaccgtcc gttagttaca agtgcaatgg ttggcttagt cttaggagat
    15841 ttcacccaag gtgttcttat tggttcagct cttgaattaa cttggctcgg tgtaacaggt
    15901 attggaggtt acactccacc agatactatt tcaggtgcga ttattggtac tgcatttggt
    15961 attttatctg gtcaaggaga aactgctggt atcgctatag cagttccaat tgcagttgct
    16021 acccaacagt tggatgttct tgcaaaaact ttagatgttt attttgtgaa aaaagctgat
    16081 aatgatgcta aaaacggaga ttattcaaag atcggttttt atcattattc aagtttggtt
    16141 ttaatcacgt tatttaaaat tgtaccaatt ttcctagcta ttatgcttgg aggggaatat
    16201 gtggcagact tgtttgctaa ggttccacca atcgttatgc agggacttaa ctctgcaggt
    16261 gctttactac cttcaattgg ttttggtatg cttttaaata tgatgctcaa gaaaaatatg
    16321 tgggtattct tgttgattgg attcatttgt tctgtgtatg gaggaatgtc aaccattggg
    16381 atctcactag ttggtattgc ggtagcatac ttctacgata tgattggaag taaaccacaa
    16441 gaaacaactt caagtagtga tgttgaggag gatcttgatc tatgatgaat aataaagtaa
    16501 ctaaagttga acttaaaaaa gttttcaaac gaagttttat gtatggttct tcatggaact
    16561 atgagagaat gcagaaccta ggttttctat atacaattct tccagtattg aaaaaactat
    16621 acccagacaa agattcagct tctcctgcaa tgaaacgtca ccttgagttt ttcaatactc
    16681 atcaaacagc ggcaccattt attcttggag ttacttccgc tatggaagaa caagaaggaa
    16741 atgaaggtgc agcttcaatt actggtatta aagttggctt gatggggcca ctggctggtc
    16801 taggagatag tttgttctgg ctgacactag ttcctatctg ttttagtatt ggtgcgtctt
    16861 attctaaaga cggcggtgct ttaggtatct ttatcgcctt aatattgttt aatattatta
    16921 atattcctgt taaatatttc ggtttgaaat atgggtatac taagggttct agtcttatcc
    16981 aagaaaataa tacaaaagga acattgaatc gcgttacgag tatggcgaca gcattagggc
    17041 tagtactagt gggtggtttg attccatcaa tggttggtat taattttgga ttagaattta
    17101 agcaggggga acttgttatt tctgttcaag aaatgattac aaaattaatt ccaggattta
    17161 tccctatggc tttgacttta ttaatgtgta aattaattag aaaaggaaag aatccggttg
    17221 tactaatctt tagtgttatg gctattggag ttatcctagt tgttttagga attttgaagt
    17281 agtagaaagt gtggaggtgg tatttgggat atcacctcca ttttggaaga gaggtaaaga
    17341 gtgaaattat ggtataagaa agctgcctca aattggaatg aagccttgcc gattgggaac
    17401 ggtcatttag gtggtatgat ttatggttca gctacaaaag aatgtattca actaaacgat
    17461 gagactattt ggtatagagg aaagtcagat agaaataatc cagactcact attgcatctt
    17521 aaaaaaattc gggaatatct tttagatgga gaaattcaga aagccgaaga attgataaag
    17581 ttaacaatgt ttgctacccc aagagatcaa agccactatg aattacttgg ggaactttac
    17641 attgagcata tagatattca gtcttgtgct ctttcattgt atgaaagaga gctagattta
    17701 gatacagcta tttctaatgt tgtgtttgag cctaatagtt gtaatttaca aataaaaaga
    17761 gaatatttta cgagttttaa taagaatatt ttatgttgcc gtatagtgtc atcagttcaa
    17821 aacacattaa atttaaacat taatttgggt agaaataaac ggtttaatga cgaagtatct
    17881 aaactggatt caagtacaat tttaatgtcg gcctctgctg gaggtagaaa aggtgttcag
    17941 tttaaagtag tatgtcattc taaagttacg gatggtgaag taagtgtatt gggagagaca
    18001 atagttattc ggaatgctac agaggtattt ctttatctca aatcaatgac ggattattgg
    18061 ggaaatatag atatttcttc tcttcaggga gaatttagta gtattgatta ctttacagaa
    18121 aaagatgaac atgtaaaaaa atatcaggag caatttaata gagttgattt taaactagac
    18181 tatagtaaag attgtcttag cattccaacg aatctacttc ttgaaaacac taaaaagtat
    18241 agtaactact tgactaactt gttatttcat tatggaagat atctgttaat atcgtctagt
    18301 caaccgaatg gtttacctgt caatcttcaa ggaatatggt gtgatgaatt aaatccaatt
    18361 tggggttcta aatatacgat taatattaat actcaaatga attattggat ggtaggtcca
    18421 tgtgatttac cagaagtaga atatccatta tttgatatgc tcgaaagaat gagagaaccg
    18481 ggaagactaa ccgctaagaa aatgtatgga gctagaggtt ttacagcaca tcataatacg
    18541 gatggttttg gcgatacggc tccccaatct catgccatgg gggctgcaat ttgggtatta
    18601 actattccat ggttatgtac tcatatttgg gaacactatt tatatttcca agatgagcgt
    18661 attcttacgg aacattttga aatgataaaa gaagcatttc ttttctttga agattattta
    18721 tttgaggtgg atggctactt gatgacaggt ccaagtgtct caccggaaaa taaatatcgc
    18781 ttaaaaaatg gtattgaagg aaatgcttgt ctatcatcta caattgataa tcaaattcta
    18841 agatattttt gtgattcatg cattggcatt gcaaaacaat taggagacaa ttcggatttt
    18901 attagtcgtg tgaaggagtt aaaaaagaaa ctacctaaaa caaaaatagg tagtaatggg
    18961 caaatccaag aatggttaga agattatgaa gaagtagagc ctgggcatag acacatttca
    19021 cctctatttg ggctttatcc ttataatgag attgatattc ataaaactcc ggaattagca
    19081 gaagcagcta aaatcactat caataggaga ttatcaaacg ctaacttttt atcttcacag
    19141 gagagggagc aagcgattaa taattggtta gtaagtggtt tgcatgctag tacacaaaca
    19201 ggttggagtg ctgcatggct gattcatttt tttgcgagac tatatcaagg tgaacctgct
    19261 tataaccaga ttaatggttt gttaaataat gcgactcttg gcaatttatt tcttgaccat
    19321 ccaccatttc aaattgatgg taatttaggt ttggtgagtg gaatttgtga attattagta
    19381 cagagccatc ataattggtt atcactaatt ccagctttac cttctgcttg gtcagaagga
    19441 gaagtgaaag gtttcagagt aagaggagga tataaggtat cgtttgcttg gaaaaatggg
    19501 gatataacat tcctaaaatt ggaaggagga aacaaagatc aaaaagtaag agtaagaata
    19561 tatggcaaaa atactgatgt acaaaatatt gaattggtat ttaattcaga aaaaattatt
    19621 gagttaaatt tttaggtata agtcatgaat aaagaaaaaa taaaaagaaa attaatcaca
    19681 atactgtttg tatgtattgg gatgttatgt tttggattgt tagcaggagt taaggctgat
    19741 aatcgtgttc aaatgagaac gacgattaat aatgaatcgc cattgttgct ttctccgttg
    19801 tatggcaatg ataatggtaa cggattatgg tgggggaaca cattgaaggg agcatgggaa
    19861 gctattcctg aagatgtaaa accatatgca gcgattgaac ttcatcctgc aaaagtctgt
    19921 aaaccaacaa gttgtattcc acgagatacg aaagaattga gagaatggta tgtcaagatg
    19981 ttggaggaag ctcaaagtct aaacattcca gttttcttgg ttattatgtc ggctggagag
    20041 cgtaatacag ttcctccaga gtggttagat gaacaattcc aaaagtatag tgtgttaaaa
    20101 ggtgttttaa atattgagaa ttattggatt tacaataacc agttagctcc gcatagtgct
    20161 aaatatttgg aagtttgtgc caaatatgga gcgcatttta tctggcatga tcatgaaaaa
    20221 tggttctggg aaactattat gaatgatccg acattctttg aagcgagtca aaaatatcat
    20281 aaaaatttgg tgttggcaac taaaaatacg ccaataagag atgatgcggg tacagattct
    20341 atcgttagtg gattttggtt gagtggctta tgtgataact ggggctcatc aacagataca
    20401 tggaaatggt gggaaaaaca ttatacaaac acatttgaaa ctggaagagc tagggatatg
    20461 agatcctatg catcggaacc agaatcaatg attgctatgg aaatgatgaa tgtatatact
    20521 gggggaggca cagtttataa ttttgaatgt gccgcgtata catttatgac aaatgatgta
    20581 ccaactccag catttactaa aggtattatt cctttcttta gacatgctat acaaaatcca
    20641 gctccaagta aggaagaagt tgtaaataga acaaaagctg tattttggaa tggagaaggt
    20701 aggattagtt cattaaacgg attttatcaa ggactttatt cgaatgatga aacaatgcct
    20761 ttatataata atgggagata tcatattctt cctgtaatac atgagaaaat tgataaggaa
    20821 aagatttcat ctatattccc taatgcaaaa attttgacta aaaatagtga ggaattgtct
    20881 agtaaagtca actatttaaa ctcgctttat ccaaaacttt atgaaggaga tgggtatgct
    20941 cagcgtgtag gtaattcctg gtatatttat aatagtaatg ctaatatcaa taaaaatcag
    21001 caagtaatgt tgcctatgta tactaataat acaaagtcgt tatcgttaga tttgacgcca
    21061 catacttacg ctgttgttaa agaaaatcca aataatttac at
//
LOCUS       DAVAZT010000041        20838 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVAZT010000041 DAVAZT010000000
VERSION     DAVAZT010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20838
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.041"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            182..658
                     /locus_tag="VQT45_001437"
     CDS             182..658
                     /locus_tag="VQT45_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2359749.1"
                     /translation="MKLSLYSEVEHYHFLSSYSLNDITYTDTPKNIIEKSKKDKYRYP
                     IVILNKDHKVIGFFCLHLNTGPKEYGYYQNDYALIRGFSIHDNFRNQGYGSNALNEIF
                     EFIDSTLKLEINHIILAVNEKNILAQKAYRNSGFSVVKKDLEGKRGKLIIMEKSRN"
     gene            complement(1332..1724)
                     /locus_tag="VQT45_001438"
     CDS             complement(1332..1724)
                     /locus_tag="VQT45_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET2359750.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLTRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTDKSQYEFLFPSVK
                     IKEEKTDKKEEVATDSSEKAEKKIRREA"
     gene            complement(1702..2163)
                     /locus_tag="VQT45_001439"
     CDS             complement(1702..2163)
                     /locus_tag="VQT45_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET2359751.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVGQLEAELDRSQFEKVEGNRLYMKQDDKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            complement(2126..2386)
                     /locus_tag="VQT45_001440"
     CDS             complement(2126..2386)
                     /locus_tag="VQT45_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359752.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            complement(2391..2819)
                     /locus_tag="VQT45_001441"
     CDS             complement(2391..2819)
                     /locus_tag="VQT45_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HET2359753.1"
                     /translation="MEGQIVKSMIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVE
                     EQIFFMEFEELYRETQKRSVASQQKTSLNLDGQMISNGSQKLTVPKGIQAPSGQSITF
                     DRAGGNSSLAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            complement(2788..3114)
                     /locus_tag="VQT45_001442"
     CDS             complement(2788..3114)
                     /locus_tag="VQT45_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HET2359754.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLDKNEDATLSKLQGDGRITEEQVKAYNEYYTKNGGA
                     NRKVND"
     gene            complement(3116..4132)
                     /locus_tag="VQT45_001443"
     CDS             complement(3116..4132)
                     /locus_tag="VQT45_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HET2359755.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLDFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            complement(4080..5021)
                     /locus_tag="VQT45_001444"
     CDS             complement(4080..5021)
                     /locus_tag="VQT45_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HET2359756.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            complement(5097..5462)
                     /locus_tag="VQT45_001445"
     CDS             complement(5097..5462)
                     /locus_tag="VQT45_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HET2359757.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            complement(5613..6671)
                     /locus_tag="VQT45_001446"
     CDS             complement(5613..6671)
                     /locus_tag="VQT45_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HET2359758.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPKKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            complement(6834..7985)
                     /gene="nagA"
                     /locus_tag="VQT45_001447"
     CDS             complement(6834..7985)
                     /gene="nagA"
                     /locus_tag="VQT45_001447"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HET2359759.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            complement(8138..9955)
                     /locus_tag="VQT45_001448"
     CDS             complement(8138..9955)
                     /locus_tag="VQT45_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HET2359760.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMIFLLSATAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            complement(10056..11198)
                     /gene="tgt"
                     /locus_tag="VQT45_001449"
     CDS             complement(10056..11198)
                     /gene="tgt"
                     /locus_tag="VQT45_001449"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HET2359761.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMLLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAECGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFRKYFVEKYGYNKSGRNF"
     gene            11328..12185
                     /locus_tag="VQT45_001450"
     CDS             11328..12185
                     /locus_tag="VQT45_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HET2359762.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            complement(12213..12857)
                     /gene="pcp"
                     /locus_tag="VQT45_001451"
     CDS             complement(12213..12857)
                     /gene="pcp"
                     /locus_tag="VQT45_001451"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET2359763.1"
                     /translation="MKVLVTGFEPFGGEKGNPTLEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSVTPERVAINQDDARISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKFPYVK
                     AGFMHIPYMMEQVVNRPTTPTMSLVDIRRGIEAAIGAMIEHGDQELKLVGGETH"
     gene            complement(12964..13332)
                     /locus_tag="VQT45_001452"
     CDS             complement(12964..13332)
                     /locus_tag="VQT45_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HET2359764.1"
                     /translation="MSIITIILTTIVALEHFYIFYLESIATRSDATSRVFNMEKEELA
                     HPSVSSLFKNQGIYKALLGVFLWYGIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKYT"
     gene            complement(13343..13768)
                     /locus_tag="VQT45_001453"
     CDS             complement(13343..13768)
                     /locus_tag="VQT45_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET2359765.1"
                     /translation="MIEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAVQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIKVKEEMESILTEFERTELSRLLNKLVLGIENIEI"
     gene            complement(14193..15335)
                     /locus_tag="VQT45_001454"
     CDS             complement(14193..15335)
                     /locus_tag="VQT45_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET2359766.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETSSAVAEEAPQGTTPAEKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            complement(15501..16121)
                     /locus_tag="VQT45_001455"
     CDS             complement(15501..16121)
                     /locus_tag="VQT45_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET2359767.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNTFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            complement(16125..17405)
                     /locus_tag="VQT45_001456"
     CDS             complement(16125..17405)
                     /locus_tag="VQT45_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET2359768.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKLTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            complement(17466..18950)
                     /locus_tag="VQT45_001457"
     CDS             complement(17466..18950)
                     /locus_tag="VQT45_001457"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HET2359769.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKGGVSKVQELQMTTQNGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVYESDS
                     YIEDPHTAVASAVYRKYQAVTGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            complement(19026..20303)
                     /locus_tag="VQT45_001458"
     CDS             complement(19026..20303)
                     /locus_tag="VQT45_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HET2359770.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            complement(20410..20493)
                     /locus_tag="VQT45_001459"
     tRNA            complement(20410..20493)
                     /locus_tag="VQT45_001459"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20457..20459),aa:Leu,seq:caa)
     gene            complement(20503..20574)
                     /locus_tag="VQT45_001460"
     tRNA            complement(20503..20574)
                     /locus_tag="VQT45_001460"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20540..20542),aa:Gln,seq:ttg)
     gene            complement(20588..20660)
                     /locus_tag="VQT45_001461"
     tRNA            complement(20588..20660)
                     /locus_tag="VQT45_001461"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20625..20627),aa:His,seq:gtg)
     gene            complement(20675..20745)
                     /locus_tag="VQT45_001462"
     tRNA            complement(20675..20745)
                     /locus_tag="VQT45_001462"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20711..20713),aa:Trp,seq:cca)
     gene            complement(20750..20830)
                     /locus_tag="VQT45_001463"
     tRNA            complement(20750..20830)
                     /locus_tag="VQT45_001463"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20794..20796),aa:Tyr,seq:gta)
BASE COUNT         6236 a         4735 c         3669 g         6198 t
ORIGIN      
        1 tggtattatc aatcatgaac taggattcta gttttgcagg aagtctaata atgaaaataa
       61 aggactaaag caataactct aaatacatct gatttttata ggatatttca taaaaaaaat
      121 ctacatacct agagtcctat ttagttatgt atcttacata aagagaaagg aattaattat
      181 catgaaatta tctttgtata gtgaagttga acattaccat tttttaagtt cttattcttt
      241 aaatgatatt acatatactg ataccccaaa aaatattatt gaaaagtcta aaaaagataa
      301 gtatagatac ccaatagtaa tacttaataa agaccataaa gtaattggat ttttttgcct
      361 acacctaaac actggtccta aagagtatgg ctattatcaa aatgattatg cgcttattag
      421 aggattttct attcatgata atttcagaaa tcaaggatat ggttctaatg ctctgaatga
      481 aatatttgaa ttcatagact caactttaaa attagaaatt aaccatatta tattggctgt
      541 aaatgaaaaa aatatattgg ctcaaaaagc atatagaaat tccggttttt ctgttgtgaa
      601 aaaagattta gaaggaaaaa gggggaaatt aattattatg gagaaaagca gaaactagta
      661 atgatactag tttctgcttt tctctaagtc tgctataaat ttataacatg ttgaaataag
      721 atgtgaataa attgattgca gaattcaaac caatttctaa caatgtttta gaaaactcgg
      781 cggactattc cagattcaat ccactatatt ctatcttatt tgcatatttt gagagaaata
      841 atctatatac taaactttta tgtttataat tcattccttt cgtttcactc aaggcacaag
      901 acagaatgaa aaagtggtgt gctctttatt ttgttttata ataatagtga gaaaacctat
      961 cactactaca aatcacgggg aggtgaataa gtgagtggta tagccactac ctcgcatttt
     1021 tataggtgtc attctttcca tcaagcacaa gaactgtgac taggagcacg taaacttata
     1081 attgaataag cgactcgttt gtgaaaggaa agaatagtca agggataggc agactcaaat
     1141 ttggtgaagg gaaacccctc atgttaaaag ccaaacttca attttaaaaa ttttaaaatt
     1201 tgtttcgtat tcactactcc ttgcctttat attggattga ttaagagaac ctttcgcgtt
     1261 tctagaaact acagtggact attctggatt caacgcatta tagttgaatt gactaggaat
     1321 tctctttctt ttcaggcttc tcttctgatt tttttctccg ctttttcgct tgaatcagtc
     1381 gctacctctt cctttttatc cgttttctct tctttgattt tgactgaagg aaacagaaac
     1441 tcatattgac tcttatccgt acgaacagtc gtcaccaagc ttgttttctt gttttgatag
     1501 ctcacctgac ctagattaaa aacctgttcc ccactttctt gctcggcttt atccttggtt
     1561 cgtttagcca tggcaaaagc aaccaatttt tctttattta aagcatagtc ttgatagtgg
     1621 gcgatttgtc gggtcaaata aaattgcaac aaaagactaa agatggctgc tatggtgact
     1681 gcgtagagga gaacacctgc cttaactttc ttctttttcc acacgataga tgaactccct
     1741 ttctaagcct ttttgaaact ggaaacgaaa atgaaccagt tgattgtcct ctgtaatctg
     1801 agctgatttg aggccataaa ccataggctg atacccccgt ccactagcat cggttttacg
     1861 aaaatcgtct gactttgact taccgatggc gatgtccttg tcatcttgct tcatgtatag
     1921 gcgattgcct tctacttttt cgaactgcga acggtctaat tctgcctcaa gttggcccac
     1981 aaacaagagc cactcctttt gctcgctttg ttgctggtag cgaacttctg aaatgaggag
     2041 ctgactcata gcttgaaaaa ggagtaatcc cccactgatg acaatgaggg caagcaggga
     2101 ttctaacaag gtaaaagcct tgaccttatg gctctttgat tgccaacaac tgttctgaac
     2161 catggtagac ctccaatccc ttttcactag aaaatacctg aatctcaact ccgttgatgc
     2221 ttacctgatt ttgccccgtc tgcaaggcca tcttagctac cctcaagact tcttcctttt
     2281 gcaagatttt tgcttcctct tgcctatttt tttgaatttg tcccaaaagg agggtcgcaa
     2341 tgctggcaaa gatagctaga gcgactactg cttccagtaa aatcactgcc ctaatttttt
     2401 gtttccttaa tgcgtttaat ttttccattt cctagatata attgatagcg aatcgctcct
     2461 ttactggtct gaaattcaac cttagccagg gacgaattgc ccccagctcg gtcaaatgta
     2521 atactttggc ctgatggtgc ctgaattcct ttaggaactg tcaacttttg actgccattg
     2581 ctaatcatct gcccatccaa gttcagacta gtcttttgtt gactagctac actgcgtttt
     2641 tgggtttccc gatagagttc ttcaaactcc ataaagaaaa tctgttcctc taccgctgca
     2701 aaagtggact ggacagagcc ggacaagccc aaggcaagga tactcacaag tcccaaaacc
     2761 aagagacttt ccagcatggt aaaggcctta atcattgact ttacgatttg cccctccatt
     2821 tttagtatag tattcattat aagctttaac ctgttcttcc gtgatgcgcc catctccttg
     2881 taacttgctc agagtagcat cttcattttt atccaagcta taaagttctg cctggctttc
     2941 caccacctta acaacagctg cttttccttt gtcattgact gcttcttttt gcttggtcag
     3001 attaggtaca aagagcaaga aaagcacgct gataatcagc aagaccacca acatctccac
     3061 caatgtaaaa gctttaacct tagctttttt caagaatgtc atcatttttt tcattttaaa
     3121 aatttacctc catattttga tacatgggca tgagcattgc cgcataaagt aaaacgataa
     3181 tcagtgccac aaagataaaa accagtggct gcaccaaatt catggtgcgg ttgactcggg
     3241 taaaaaaggc ttcccaagtt ttttcagcat agatttccaa ctcactaccc agcttggact
     3301 taacttcccc atactctatg atgagactca attccttcct aaagaaagga taggttccta
     3361 tcgtctgaga aaattcacgg ccatttttca gggtttgagc cagatcttga ccgatttctt
     3421 taaagagctg ggaaccttgt tcctgcatca tttgaaaaat ctgcgtcagc tccattccct
     3481 gtgaaatcat attcccccat tcacgtgcat aataggctgt caagtaggtc tgcacaaaga
     3541 ttccaataaa gggaaggcgt gctaagatag aaaagacact catcttagaa cttcttttat
     3601 aaaaagttag tgctaaaagg gcaagcacgg aaacaagccc taccatgcct agaaaaattt
     3661 gtggcagatt accgataatt cgggtggcaa tattgctact atccagttgt gggagcaggt
     3721 aattccgtag ccccagcata attaagagaa gaaaatccag caaaatcaaa ggataggtcg
     3781 ctacttcaat taactttttc ttgaccttgg ccagattgtc tagatattct tctatctttc
     3841 ccaaactcag gtgaagattg ccatgaactt cagctagaga taactgagtg acaatggtac
     3901 ttgaacatcc caaactttcc atcatttctg agaatgattt cccctgagac aagcctgtac
     3961 gcatctgggt cacacactgc ttgtccaaca aggaactcct atctaaaaag gagatagtct
     4021 ccaccagatg aaaaccgcta gaaaagagat tgttaaatag ggtgatgata tttttttgct
     4081 tagctgtagc taattttttc cgtctcagcc tgaagacttg tgatatgtcc atctttaaga
     4141 agttggtcaa tttgctcatt ccacttggct gcttggtgtt cttgataatc tctgtttgca
     4201 aagtcaacga ttcctcctcc cccgattaat ctctggtagc agactccttg cagaacaact
     4261 gccaattctt cttcactcac acccaactcc agcagacgct cataaacacc tcggatactc
     4321 ttggcgtgaa tggttgaaaa gactgtcgca cctgtcaaac tagctctgac cactgcacgc
     4381 gccgtctcgc tgtcacgaat ttctccgata atcaagagat ctggtcgatg acgcaaggaa
     4441 agtttgatta gattttcata ggttaggccg attgcttcgt tcaactgcaa ctgaagcatg
     4501 tcgtcctgct tgatttcgac aggatcttcg atggacataa cttgctgtcc tttaaagagt
     4561 gacttggaca attcatgcat caaggtcgtc ttaccactcc caaccgggcc agcaaaaaga
     4621 tagagtcccc gttgcctgta ctgcttgcct aattcttcaa tatcctgaaa ccaaaaatgc
     4681 aagtcctgct cctcatcgtg caacaaacgg ataaccaaac tctcatgccc ccgataatcg
     4741 cctacagtag ataaacgtag agacgccatc ttctggtcat aggcataatc acaggaaccc
     4801 agttgactac gtcttttttc tcccacattc atacccgcca caaacttaaa gtgactgata
     4861 acggctgcaa acttttcaaa atcatagcta ccaattttac agcgctcgtc tcctaccctc
     4921 atatgaagct cataggcgtc taacttaggg acaaaataaa tatcctgcgt cccttttttc
     4981 cgagctgaac gaatgatttc ttgtgcaatt tcttgaacca tacttacctc ctcacctata
     5041 ctattcgcaa agcgttagaa aaataaaaaa agcaactcca aaaaagttac ttttctctat
     5101 tttaatttca tacggcaaga acgattcctt tcctgactgg tttgtttttc atagcctgag
     5161 cgtagttttt cgtctgggat aacctgctca tcctgcaaaa gagccaaaga atggtattgt
     5221 tgtaaatact catcacattc atcacaccag cgttggtctt ccgggtccca aaaaatggtc
     5281 atcaagtcgc ttctactttt ataaagaggg gattcttgtt ccaatctaaa ccagcaagtt
     5341 ttgtagtatt tgagagcatc ataatactgg tcaaattttc tacttgctac aatatcttct
     5401 tcccaacctt ctaagaacca ccacggttca aaatctccgt acatttctat aacacgatac
     5461 atattcattc attcctttgt accgtatatt ataaccaatt ccgccagaca aggaaagaaa
     5521 tatgctcatt tcttaatttt ttgataaaaa atccagccat ctgatggatg actgaatttc
     5581 tatttgctta tgtacaaaaa tatttttact acttaggctt ctgagatatc gttttcgata
     5641 atgaccttaa tggcatggtg gtctgctgcc ttactgaaga cttcgtaggc tttttcaatt
     5701 tcactgagtt tgaaatagtg agttaccaat ttttccggtt caatcttatg actttcaagt
     5761 gctttcaaca attgtggagt cgtatttgta gataccaaac cagttgttac attgatgttg
     5821 cgaatccaaa gtttatctaa atcgaattca actggtttac catgcacacc acagttggca
     5881 accgttccgt ctacaccgat aatcttttga cagaaatcaa atgtttcagg aatccctaca
     5941 gcttcgatag cgacatccac accacgacca tctgtcaaat cataaatttc tttaatggct
     6001 tttttagggt ctgaagaatt aaccttatga gtcgcaccga atgatagggc agtttccaag
     6061 cggttatcgt ctaggtctac cataatcaat ttagctggtg aatagaattg ggctgttaaa
     6121 agagcagcca atccaactgg acctgaacca ataatggcta cgctgcaacc aggttctact
     6181 ttccctttta agacaccaat ttcatatcca gtaggcagaa tgtctgacag cataaccaaa
     6241 gcttcatctg acaagtcttc tggagtatgg taaagagtat tatctgcatg agggacacgt
     6301 agatattcag cctgcatacc atcaatcaag tgaccgaaaa tccagccccc ttcgtcttca
     6361 cagtgggcat aaattccttt tttacagtag tagcatttac cacaggcaca gacgcaagaa
     6421 atcaagacct tgtcaccttt tttgaagttg gaaactcctt ccccaacttc ttcaacaatc
     6481 ccaatccctt cgtggccaag aatggtacca ctttggcaag taggaacatc ccctttgata
     6541 atatggaggt ctgttccaca aatagtggtt tttacaatac gcacaatagc gtctgttggc
     6601 ttgcgaataa ctggtttgtc tacatcaaca aaagaagcaa gtcctggttt aacataagta
     6661 taggctttca taaagcactc ctccgttttt ttatttgtaa tatttatagt tcaattgtaa
     6721 gcctttttct ttgtttcttc aagctttttt tgtgattttt ttaacttttt atttaccagt
     6781 aaagtaccct gtataaaaaa gcagaagcta gtctctaact tctgccttct ctcttatgct
     6841 tgataacgtt tcacaccatc taggtaggtt gctaccaatt ccaaatcttt atctaatacg
     6901 atgaagtcag cgtcgtagcc ttcacggatt tggccacaga cgtcatcgat gtgaacggat
     6961 ttagctgggt tgaagctggc catcatgact gcttcatgcg gattcgcaat tccccattcg
     7021 accacattct tcaaaccatc tttgagtttg aggatagaac ctgccaagtt acctgtcgat
     7081 ttgaggcgtg cagttccatt tgcaacgaca actgggaatt ctcccaacat ataatctccg
     7141 tcttccaatc ccccagctgt catacagtct gtgataagag cgatgttttc tgttcctttt
     7201 tgtttgataa gaatttcgca agcctttgga tctacgtggt gaccatcaca gatcaactct
     7261 gcataggtat gtggcaattg gtacatggct ccaaccatac ccaattcacg gtgagtcaac
     7321 ccacgcattc cattgtaggc atgcacccaa acactcgctc cagcatcgac tgcttttttg
     7381 gcttcatcaa aagtcgcgtt tgaatgtcca agagcaaccg tcacaccttc gcccgtaact
     7441 gtacgaacaa agtcttccac cccatcacgt tctggtgcaa gggcaatttt attaagcaag
     7501 ccatttgccg ctttttgcca agaatgaaac tcctcaacac ccgggtctct catataagtt
     7561 ggattttgtg cccccttaaa agtttctgtg aaatatggac cttcataata aatcccacga
     7621 atcttagcac ctgttgcttc tttataatgg tttccaagat tttcagtgac tgcaagcaat
     7681 tgctcataag tggctgttaa agttgtgggt aagaaactgg taacaccggt actaagaagt
     7741 ccttcactca tagtatgcaa tgtaccttca atgttgttgt ccatcacatc tacacctgca
     7801 tatccatgaa tatgagtatc cacaagtcct ggggcaatgc tataacctgt atagtcaatc
     7861 acctcagccc cttcaggaat ctgctctaca tgtttcccaa acttgccgtc cacaagttcc
     7921 aagtaaccac ctcgacgaac tccgtgtggg tagaaaaact gatccgcttt aatatagtta
     7981 ggcataatgt taacctcctt aaaagattga ttctacaatt tattatgtca attacattat
     8041 aaacctttct tttttatttg taaatggtat agacctattt tttggagata ttttaaaaga
     8101 gctggatttc tccaactctt ctctttttta atacaagtta ttttgattta accggcttgt
     8161 cttgagctgt ctgcaaagct gtggcaatcg tatctgcata caattttgct cctgcttcga
     8221 tagtgctact ctcactcccg aaatgaacct ggtctgttcc agcccaaatt tctggatgct
     8281 ctttcgcaac ttgattccaa tctgctatcg taatgtaagg tgtcttctct gccaattctc
     8341 tcatataggc agcagccttc tcaacgatgg cataggtctc ttttgtctta tctccctcat
     8401 aaggagtcac caaaatcata tggtgtccct taggaagatt tttcacgata ctgtcccagt
     8461 catccttgta attctcagga ttatttaccc cagtcgcaat gaccaccgtc ttaggtaaaa
     8521 atttattctg gctattattt agcatgattt catttgcggt cttggttgtt acgctgacct
     8581 gcgcgttaat ctgtgctcca ggaagagctg tctgtagtgc tgtatttgcc cttaaagcca
     8641 ctgagtcacc aattaacata gtgccatcag caattcccaa actgtttgca tctgcccgtt
     8701 ctgccatcac cttggtctgg ccaatatttg ttgcagcttg cttcaagcca ttgacagtca
     8761 agtctgtctc aaacgctccc acttgtggtg ccaacaaggt caccatgcag acaatgaagg
     8821 tcaagattcc tgtacctgct gcaagaattg cgtgaatata aggcagggga cgaagagttt
     8881 gtaaaatagg tgtgttcttg cctgcaatcc aaggttccaa tacataaaat gacagactgg
     8941 caaagccata agaacaaatc agagtcagta atacagcaag aagatttgat gtcaactgtg
     9001 agaaaatgat atagaaaggc caatggaaaa gataaaccgc atagctagta tccgctaaaa
     9061 agctgataat cttcggctcc tgtatatgat gtgtcttttc atgtaagaca cgcgccgcca
     9121 gaatcatggc aagagctgca agactggcaa gcaagaagcc gataagatag gcaaaaagat
     9181 aagtgaattt gacaaagaaa gtcaaaagaa ctaggaaacc aaagcctcct ccaaaaacta
     9241 ctaaagtctt tcgtaaatcc cagattttat ccaactgctt gacgagggaa gtcgtctgac
     9301 gaacgcctac aatagttgct aacatacttc ccaaaaagaa tggatagaca tgagttaaac
     9361 tggagaaata aacagaggaa taagaggtca ctagaaaact accaataaac atggagaaga
     9421 aactgatcaa gaaggcagta gcagataaga gaaagatcat ccccttcaac tgaccatttg
     9481 atttagcttg tttggataag aaccaaactg ccaatcccca aagaatatag tagtgaacct
     9541 caactgccaa actccaatta tgaacaaaca aatgaggaat gaactgagat tcataactcc
     9601 cacctgttaa gagttcatag aagttggtca taaagcctaa gacgcccgca atctggccac
     9661 caattccagc aacatagtct tggcgaacca agaaagtaaa aggcatggtc accaagacca
     9721 tcaaaaccac aggtggcaca atccgataaa agcgtcttct aaaaaatcct atcaaatcaa
     9781 tctcattgtt cttagaaaat tcttcaatga gtagagctgt aatcaggaaa cctgaaaatg
     9841 tgaaaaagac atctaccccg aaaaatcctc caggaaagat cgtctgaaag aagtgataca
     9901 agagtaccaa aagtaaacct ataatcctaa tcaaggaaaa ccatttaatg cgcatacgag
     9961 tttattcttc ctttcattgt acactttatt ctatcaaaaa aagaagaaaa atcctaagag
    10021 aaaacttagg atttttagct tatatcaatt ccattttaga aattacgtcc tgacttatta
    10081 tagccatatt tttccacaaa atacttacgg aattccaaga gattgtcatc catgatggct
    10141 tgtcgcactt gcttcatcag gttaagcaag aagtaaagat tgtggtagct agtcaagcgg
    10201 ataccaaagg tttcatcagc cttgagcagg tgacgaaggt aagcgcgtgt atagttatta
    10261 catgtgtagc aatcacactc aggatccagt ggcgtaaagt cctcagcaaa ctgggcattt
    10321 ttcacaacca aacgtccttg actggtcata caagtcccgt tacgagcaat tcgagtcggt
    10381 aagacacagt caaacatatc caccccacga atgaccccat cgatcaagct atctggcgct
    10441 cccacaccca tcagataacg aggtttattt tcaggcagca gttgagttgt aaagtccaag
    10501 accgcattca tctcttcatg ggtttctccc actgccaaac caccgataga gtagcctgag
    10561 aaatccatgc tgacaagatc gtgagctgat tggcggcgaa ggtcttcaaa tcctgcacct
    10621 tgcacaattc caaacaaacc ttggtcatgt ggacgacggt gagccttcaa accacactca
    10681 gcccaacggc tggtacgctc gatcgatttc ttaacgtagt cataaggttg ataaaactga
    10741 ggacattcat caaaggacat catgatgtct gaacccagat tattctgaat agagatggct
    10801 ttttctgggg ataggagcat cttagaacca tttagatgat ttttaaaggt tactccttct
    10861 tctgtgatat tacggctatc tgctaaagaa taaacctgaa aaccaccact atctgtcaag
    10921 ataggctggt cccaattcat gaacttgtgg agaccaccag cgcgtgcaat gagttcatct
    10981 ccagggcgaa gccagagatg ataggtgttt gataggataa ttcccgaacc catctccttc
    11041 aattcttcag gtgactgagt tttgacagtg gcttgtgtcc caactggcat aaacataggt
    11101 gtcggaaagg taccgtgggg agtgatgatt tctcctagac gagctcctgt gtgtttttct
    11161 ttcttaatca aacgatattt gattggtgaa tctgacattt tttacctccg aagctgggaa
    11221 agacagtccc agttcataca gtgtgcccaa ggacacactg tatgatttta tcaaaaaaag
    11281 taggaactgt cacgaactat gtataagaac tatggtataa taagagaatg aactatccaa
    11341 aaattgattt aaaaacaatt cgtcaggagt caaaacattt tcaggctgac accccccgtc
    11401 tctttctcct ctatatcctt cccagtatgc tggtcatctt atctggtttt cttaatccct
    11461 tatctcggat ccacgggact gttttagaac agccattttt cagcatactt ggccaaatac
    11521 ttcaaaccta cctctttcct ctactagtct cctttatcgg gactattctt ttgaccagtt
    11581 ccgtctatgc aacactgaca ctcatgaaag attctaaaac ggagccatct gtaaaaaaca
    11641 gcctagctct ctttgatgag gagcgctttt ctcaaacctt tttgacccta cttctcaaac
    11701 gtttctatct ctttttatgg agtatcccta atttacttgg gatttacctc ctcttttata
    11761 gtagcttttt agccaaaaaa ttcgtcaccc tacatcctga gtttccaaat ctagatctct
    11821 catcagttga aaccgagcgt ttcctcatgg tctttggact ctactttctt gcaagtctca
    11881 tcttgatcat tgtaggaaat atcctctata ttccacagta ttatgcctat tcacaggtgg
    11941 aatttcttct ctgttatagt ctagacctag gacaggtccc accaagacga atcctaaaaa
    12001 ctagccgttc ctttatgaag ggctacaagt tccagcactt tgtcctagat ttacagcttc
    12061 ttccttggta cttcctcaat tggattacct ttggcattgc tagtttttca ctcctacctt
    12121 atatccaatg cactaaaatt atgttttacc gagcagtatt ggctcgaaaa cgtccaaaag
    12181 cttgaaggtt tttcccctca agcttttttc tatcaatgag tttctccgcc taccaacttg
    12241 agttcctgat ctccatgttc tatcatagcg ccgattgctg cttctatccc tcgccgaata
    12301 tccactaaac tcatagttgg agtagtcggt ctgttcacca cctgttccat catataagga
    12361 atatgcataa aacctgcctt aacatatgga aatttctttt ctaccaaata gagagcctga
    12421 tacatcaaat ggctgcagac aaaagtccct gccgtattgg aaacagaggc cggtaagccc
    12481 tcttttttta tagcttgaac catcgcttta atcggcaaac tactaaagta ggccgaagca
    12541 ccatctgggc gaatgggacg gtcaatcggt tgattatctt cgttatcaga aatgcgtgca
    12601 tcgtcttgat taatggccac tcgttcaggt gtcacactag ttcttccacc agcttgccca
    12661 atacaaagga caaagtcagg ttgataacga ttcatctctt cttccaatac ttgagcagat
    12721 ttgtgaaaaa ctgtcggcac ctctagccaa cggacctcag caccatggat ttcagctggt
    12781 aaacctttaa tggcctccaa agttggattg cccttttccc ctccaaaggg ctcaaaacct
    12841 gtcactaata ctttcatttc taactcctca aaaccaattc aatgagactt ttttcttaaa
    12901 aacaagtata acatatttcc cttattctgg attaaaaagg attagcgaga ttaaaatcga
    12961 ccttcaagtg tatttaaaga gtaaaatact aatcaaggcc aaaatagctg atccaccttg
    13021 cttcaaaata atttttttat ccgctgttaa agagccgtaa gtcgcagcac caatcacaaa
    13081 taagacaaaa atagtcacaa tttctaaatt ctgtgagaaa taaatgccat accagagaaa
    13141 gactcctagc agagccttat aaatcccttg atttttgaac aatgaactta ctgacggatg
    13201 agccaattct tccttttcca tattaaatac acgactagtc gcatctgatc gcgtagcaat
    13261 actttccaaa taaaaaatgt aaaaatgctc caaagcaacg atcgttgtta aaataattgt
    13321 aataattgac atctatttct ccttaaattt ctatattttc aatacccaaa accaatttat
    13381 ttaataaacg gctgagttct gttctctcaa actctgttaa gatactttcc atctcttcct
    13441 taaccttgat atgttgcaga gggggattca ccactaactg ctccttggca tacttcgcag
    13501 cctctaccaa cacttcccgc tgattttcag gattacgatg acgctccacc aaaccttccg
    13561 tttccaaaat cttgaaatgc cgtgtcaaag cagcctgatc aattttcaaa cgctcctgaa
    13621 ccgccatttg gttacaagga gaatgctcca gcaaaaacag taaaatctga taccgtgtca
    13681 aactaatccc aagccttttt tcaaacaatt gcgtactcgc ttgctcagac aagcggagtt
    13741 gatacagtaa atcttgaatc tctatcattt cttcctccta tccattgact tatcaatagt
    13801 tgaccaatca attataatat aaagtatagt gaaatgaaat aagagcagga caaatcgatc
    13861 aggacagtca aatcgatttc taacaatgtt ttagaagcag ttgtgtacta ttctagtttc
    13921 aatctactat aaaatagatt gcaagaatgt tgcttagatt attacaagat gataactttc
    13981 cattttccat tcaaattgat actcaatgaa aatcaaaaag caaactagga agctagtcgc
    14041 aggttgctca aagcacagct ttgaggtttc agataaaact gacgtggttt gaagagattt
    14101 tcgaagagta tgacaaagaa aaaacgaacg agaatcgctt cccatcacga aagctagatc
    14161 tcattcgtca aaatgatgtt accaagtcgg gtttatccat tcattgaaac gtgaacgtga
    14221 tcatagtgat tttctgtcac actaccacgg tctggcattg ggttccaagt gttagctggc
    14281 ccatatttgc tatcgaatgg agcatagaaa cgttgtttcc agatgatgta actaatgcca
    14341 cggctggcca tgttttgaat agcatattcc gcaatcttat cccctaattc tgaacgttct
    14401 ggtaccataa agtcgatagc caaacctttt ccgtgatctc cactgtctcc tggacgataa
    14461 ccgctaaagg atgtaatgcc aaacaagtta gcaatttctt ctttaaaggc agctgtttgt
    14521 ggttgaagac ctgcattttc agattttgct actgcaagtc cagcataatc gggcgcagct
    14581 ggagcctcgt aagttgttga aattattttc gtctcttctg gttgataagt agaaactgct
    14641 gctgtagctc catttgatga tgctacttct tttgcttctg aacttgttgt agttgcttcc
    14701 actgctgatg cagcttgagg gcttgcttgt gtttcctgct tctcagctgg agtcgttccc
    14761 tgaggagctt cttctgcaac tgcactgctt gtttcggccg tttgctcctc tgggacagaa
    14821 gtgcccgtag atggtgccac ttcttcagaa gcaatcactg tctttgtaac ttctgaactt
    14881 gatgctactt cttttggagc ttctgcaatt ggttgagaaa ggtctgcaac ctgaacagtt
    14941 tgatcatcaa cggtcacttg attagtggtc aaatctgctg tcgcagttgt cacttcttca
    15001 ctagagtctg cttgaggtgt ttggatttca acttctgtta cttcttctgc ttcattgaca
    15061 gtcgttgtca aaacagtttc tgggaaaatc aagtccatat tagtgatttt gttcagattc
    15121 gcaagcactg tgacatctac acccaaggct tctgcaatgg tgctcaaagt atcaccatac
    15181 tgtacggtat aacttgtttt gttgtccgtt ttagtcaaat cgttttggat ttgctcaaca
    15241 ctacgtgcag tccaaagaac ttcttctgct tgagttgcca atactggggc aaatgacaag
    15301 gctactgttg acgctaataa cattcttttc ttcattcttt caaattcctt tcaaatgagt
    15361 acctgtctat cataacacaa aaaatgtaga aaaaaagccc tctcgggcct atttaacaga
    15421 actgtctatt ccttgtaaca aactagatta cttgaaatag tttgttaggt ctctgtcaca
    15481 aaactgacac aatcttttta tcacttagtc tcaaaaatac gggaaatatc tgctaacgct
    15541 tgaatcctgt gattcccttc ataagtagac tctaaaaagt tgatactttg aatcccacta
    15601 ttctgggcaa attccacatc cagagtccga tcccctatat aataagtatt atcagaattc
    15661 aactgatact tatctagcag ataggtagcc gcttctggac ttggcttccg cacaaagcca
    15721 ctctgactgg tcaaaatctc tgtaaaatag gattccaccc ccaagtcctt gagaatggta
    15781 aaagtgttgt tccccttatg agtatatata aactgctgaa ttcctgattc gtctgcccaa
    15841 gctagcacct cacgcgcacc tggcatcaaa actacctgag cattcttctc agccagactc
    15901 tgggcacgca cctgatttag cacctcaaca tccagatttc tatcttctgc cacccgcaca
    15961 agcaaatttt gcaccgaata cttgaagata aactctctca ccttctcctt atcataagga
    16021 atagaaaact gagcaaaagt ctcctcaatc cctgataaaa tcgcttcgta agagtccaat
    16081 aaagtcccgt ctaaatccca aataaaagct gttttttgca tttcctatcc tttcaagctc
    16141 atatagcgct ggtaacgata gcgtagaaat aaccagcgaa aaccattatc caagagagac
    16201 cctgcccaaa taccaggcaa gccccaacca agcacaatac ccatcagata tcctgtccca
    16261 atgcggatac accacatgcc tatacttgtc gcataaaaag ggaggcgtgc atttcctaat
    16321 ccctgccaga ctgccgtata gatgactgtt cctgtcgtca taggggtacc aagtagtgaa
    16381 aacagtgtca ctagaacact agcctccacc gctagagaat cagtcgtata gagatgagtt
    16441 aatggtacac ccaagacata tatactaaag gacaggggca acatgaggaa cagagaaagc
    16501 caaaaggttt gtttactcaa actagcaact cttttccaat catcctctcc aactgctcgg
    16561 gccaacagca tgaccgttgc cgtagcgaca ccaaaggcag gcatatagtt aaactgggtc
    16621 aagacttctc cgattgcatt cccagcaact gcctccgtcc caaaagaaac gaccaaggca
    16681 atgatcacta catctccagc cctcatcata agtcgctctc cagctgctgg taaagccaag
    16741 gtcaacagtt ccttatctaa accaaaagtt agcttcccat aaggcagttt taattgtgac
    16801 cacaaaatca caagaccaac caaacgagac agaattgtcc cccaagcaac accagctatc
    16861 cccatatcca gaacaaaaat agctagactt gaaaaaagaa tattcaaggc attggataaa
    16921 aaactaacat agagaggcag acgtggatta tgcgttgcac gaatcaaggc tcccaaacta
    16981 gtcattaaac ctaagagaac aatcgatccg cctaccaaag atagatacag tccaccactc
    17041 tcagctacat ccctctccgt ccccaaaagt cctatcatct ctttcccagc gaagatggac
    17101 aaaaatccta aaaggaaact taatagtaag gtaatcttca acgcctcagt cacatgatag
    17161 gccaacttcg actggtcttt ctgccctatg ctttttgaaa taacactgga aatagcagct
    17221 cccagagcga tgaaaatcgc ctgataaatg gtgataatat taccagctac tgaaacccct
    17281 gaaatagcta tcaatcctaa atgagcaacc aaataactgt ccaccattcc cattagcatc
    17341 tgcaaaaagt tttcacccat agctggcaat gcaatattaa gaatgtcttt atttttctta
    17401 aacaatctct cctcctgatg aaaagaaact cagttggttt cccaaccgag tttgctccct
    17461 ctgtcttaaa gtcctaaata agcctcaacc gctgcttgca tgtcagcagc tgccactgtt
    17521 gtcttgtgac gaattggagc tatttcaagc ccatcaactg ctggtggcac tgcaacgcct
    17581 gagatttcat gtaattgagc caaggcttca aagtctgtca aacctgcttt tccagttaca
    17641 gcttctactg caactactgg gaacttgtat ggactagctg ttgaagcaat cactgtctta
    17701 gttacatctc cagtaaccgc ttggtatttt ctataaactg ctgaggcaac cgccgtatgt
    17761 ggatcctcaa tataagaatc tgactcataa acacgcttga tttctgccgc tgtttcttcc
    17821 tcagtcgcat attcagctgc aaagaggtcc aaaatctctg catcaaagtc tgtcaactta
    17881 tattgtcctt gcgtgttcaa ggcattcata agttcagctg tcttttcagc attatttccc
    17941 aaaagatgga aaatcaagcg ctccaagttt gaagatacca agatatccat agatgggctg
    18001 gttgttacct taaactcacg ttttttgtca tagacacgtg ttttaaagaa gtctgtcaag
    18061 acattattgt catttgaagc acagattagc ttgccaactg gtaggccgat ttgtttggca
    18121 taaaaggcag ccaagatatt tccaaagttt cctgttggta ctgtgaagtt aaccttttca
    18181 ccagctacaa tttcaccagt cttaaccaat tgagcgtaag cataaacata ataaacaatt
    18241 tgtggcacca gacgaccaat gttcatagag ttagctgatg aaaattgcaa cttgttggta
    18301 gtcaattttt cacgaagagc cacgtcgtta aacatgtgct tcacatttgt ttgcgcatcg
    18361 tcaaaattac catcaatagc aataacatga gtattgtcac cattctgagt ggtcatttgc
    18421 aactcttgta ccttgctgac accacccttt ggataaaaga cgataatctc agtaccaggc
    18481 acatccgcaa accccgccat agcagctttc cccgtgtcac cagatgtcgc tgtcaagata
    18541 acaatcttgt tctccaaacc atgtttctta gcagcagtcg tcataaagta tggcaaaata
    18601 gacaaggcca tatccttaaa ggcaatcgtt gaaccatgga aaagttccaa attgtattgc
    18661 ccatctaatt tcactaatgg tgcaatagct ggagtatcaa atttgctatc gtaggcattg
    18721 ttgatacagt agtccaactc ctcagctgta aagtcatcta aaaatgctga caaaactagc
    18781 ttagcaactt cctggtaaga agcatctttc aatttgtcaa agtccaaatc tacctttgga
    18841 taagtaaccg gtgtaaacaa accgccgtcc gtcgccaaac cttgcaaaat tgcttggctg
    18901 gcagttactg tattgttggc atcacgcgtt gattgataaa ctaatgtcat tactctctat
    18961 cctttatcta tagtctcgtc cattatatca tgatttttca gaaaattctc cctttataag
    19021 agaaattata ggctcaattc ttctctcaaa ggctgtaaat aggtcatttc ttccttattt
    19081 ctcaccacta gtccctcctc agctagtagg agtaagtctt tggaaaattc aataatcgta
    19141 gtttcttcct catctgtaag atttttctta gaaaattgtc tccttaaaga cttgtaatca
    19201 taaccaaata ctttaaagaa aggtgctgtt tctaagtaag cttctaactt gtctaaatta
    19261 accaataatc ccaagtgaaa agctgcagaa gcaaaagtcc tatcaagtgg ctgtgtacac
    19321 acactacgaa actcaactgt tcctcgagtc gttaaatctt ggtactggta actacgatga
    19381 gtttcaaaat ccttctcttg ggggtaaata ataacctcat ccccattcag agcaaatgct
    19441 tggatttcgg acgtagccaa atagtcccca gcctgaatag gataaaaata ataggtctgc
    19501 ccatcacgtt ccgcagtaaa aatcgcagaa tgatttagat agtcaaaaaa atcagcttca
    19561 tcattaagga gtctagcatt gaccccaaca ttctctggat agataccatg catagattct
    19621 tcccagaaaa tatcccttga aattttcgta tcccaatccg cacccgaaaa ttcagagttt
    19681 gcaaataaat aagccttagc cgcttcaatt tgagtaaaag cattaatcac ccgtaagtag
    19741 ttggtttttg aaatatccag ctgaacctgg ctcccacaga taaaagtacc atattcaggg
    19801 aaatgatgta aatctgattt aataatattt ctactcaaat tcaaataatc catcaacatc
    19861 tgatagcgtg gataagccac tggacaattc tcatttttat cccagttggg atggatacca
    19921 cagccaacaa tagcatgatt tgattcagct aactttctct gaattacatt catataatta
    19981 ttgaaacgat tttcgacctc ttgaatcgtt tcagccttac caaatgcaaa ctcaatcgtt
    20041 gtataggaaa cttcaaataa aatagcatcc tgacttatcg gatctactaa ctggatcaga
    20101 ttgccaaaat catctacctt tgctacggtg agatccaaag tagaaactaa ataatgaaat
    20161 agatccttta taacttcaac atctgtagca tccccttcta aacttgcaac aggatactcc
    20221 aactcaattc cgacaaacaa ttcaggattt tctttaatat ttttcaaata ccgatgtttt
    20281 aataaatcga tagaacaaga catactaccc tacactttct taatctaaat aaaatttgaa
    20341 taactataat tataccaaaa ataatataaa aaaggaacga agaataacaa cgttcctaac
    20401 actatactat accggcggcc ggggtcgaac cggcacgtcc ttgcggacac tggattttga
    20461 gtccagcgcg tctgccaatt ccgccacgcc ggcaaatagt aactggggta gctggattcg
    20521 aaccaacgca tgagggagtc aaagtccctt gccttaccgc ttggctatac cccaataata
    20581 taaaataggc gagtgatggg gatcgaaccc acgcatgcca gagccacaat ctggtgtgtt
    20641 aaccacttca ccacacccgc cataattcta ttaacacggg cagtaggaat tgaacccaca
    20701 ctgaaggttt tggagacctt agttctacct ttaaactatg cccgtaaaat ggaaggggag
    20761 ggattcgaac ccccgaaccc gaaggagcgg atttacagtc cgccgcgttt agcctcttcg
    20821 ctacccttcc aaaatata
//
LOCUS       DAVAZT010000042        20770 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVAZT010000042 DAVAZT010000000
VERSION     DAVAZT010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20770
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.042"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(41..961)
                     /gene="cysK"
                     /locus_tag="VQT45_001464"
     CDS             complement(41..961)
                     /gene="cysK"
                     /locus_tag="VQT45_001464"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HET2359771.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKLGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(1246..1881)
                     /locus_tag="VQT45_001465"
     CDS             complement(1246..1881)
                     /locus_tag="VQT45_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HET2359772.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVSVNLV"
     gene            1937..3235
                     /locus_tag="VQT45_001466"
     CDS             1937..3235
                     /locus_tag="VQT45_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2359773.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLSLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVIEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            3232..3894
                     /locus_tag="VQT45_001467"
     CDS             3232..3894
                     /locus_tag="VQT45_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HET2359774.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQACQFWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            3974..4522
                     /gene="raiA"
                     /locus_tag="VQT45_001468"
     CDS             3974..4522
                     /gene="raiA"
                     /locus_tag="VQT45_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HET2359775.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            4658..6631
                     /locus_tag="VQT45_001469"
     CDS             4658..6631
                     /locus_tag="VQT45_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HET2359776.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDALGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNTVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            6628..7080
                     /gene="rplI"
                     /locus_tag="VQT45_001470"
     CDS             6628..7080
                     /gene="rplI"
                     /locus_tag="VQT45_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HET2359777.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            7124..8476
                     /gene="dnaB"
                     /locus_tag="VQT45_001471"
     CDS             7124..8476
                     /gene="dnaB"
                     /locus_tag="VQT45_001471"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HET2359778.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            8478..8744
                     /locus_tag="VQT45_001472"
     CDS             8478..8744
                     /locus_tag="VQT45_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359779.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            8833..10179
                     /gene="cbpD"
                     /locus_tag="VQT45_001473"
     CDS             8833..10179
                     /gene="cbpD"
                     /locus_tag="VQT45_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HET2359780.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSGTVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      10262..10364
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            10435..10725
                     /locus_tag="VQT45_001474"
     CDS             10435..10725
                     /locus_tag="VQT45_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HET2359781.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            10688..11446
                     /locus_tag="VQT45_001475"
     CDS             10688..11446
                     /locus_tag="VQT45_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2359782.1"
                     /translation="MRNLKSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            11484..12491
                     /locus_tag="VQT45_001476"
     CDS             11484..12491
                     /locus_tag="VQT45_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2359783.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            12491..13219
                     /locus_tag="VQT45_001477"
     CDS             12491..13219
                     /locus_tag="VQT45_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2359784.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            13338..13796
                     /locus_tag="VQT45_001478"
     CDS             13338..13796
                     /locus_tag="VQT45_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HET2359785.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            13798..16230
                     /locus_tag="VQT45_001479"
     CDS             13798..16230
                     /locus_tag="VQT45_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET2359786.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFMELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALVLGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     ALRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKVKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            16872..17525
                     /gene="rr06"
                     /locus_tag="VQT45_001480"
     CDS             16872..17525
                     /gene="rr06"
                     /locus_tag="VQT45_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HET2359787.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            17522..18862
                     /gene="hk06"
                     /locus_tag="VQT45_001481"
     CDS             17522..18862
                     /gene="hk06"
                     /locus_tag="VQT45_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HET2359788.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILFLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGEVGKQINGMYEHLLKV
                     IHELESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIA
                     KSINKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIEN
                     QLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQE
                     LEHLFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            18945..19472
                     /locus_tag="VQT45_001482"
     CDS             18945..19472
                     /locus_tag="VQT45_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HET2359789.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            19551..>20770
                     /locus_tag="VQT45_001483"
     CDS             19551..>20770
                     /locus_tag="VQT45_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HET2359790.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEGVRSGD
                     TPKVTSSGDEVESHLKKILSEIQTQLDRKRHAKTVALINKLQDIKRTYSYKLNVLEEK
                     PKAELTSKTKEELTAAFEQFKKDTLPTEPGKKVAEAEKKVAEAEKKAEDQKEEDRRNY
                     PTNTYKTLELEIAEFDVKVKEAELELLKEKAKKPLNEGTIKQAKEKVESKKAEATRLE
                     NIKTDRKKAEEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAPKPEKPAPAPKPENP
                     APKPEKPAPAPKPENPAEQPKAEKPADQQAEEDYARRSEEEYNRLTQQQPPKTEKPAQ
                     PSTPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQNNGSWYYL
                     NANGSMATGWLQNNG"
BASE COUNT         6521 a         3436 c         4706 g         6107 t
ORIGIN      
        1 ctagtctgga gatttttcaa tagacttcgt tattggacgg ttacaattca taaagtgctg
       61 tagagagata acgttcaccg ttatctggtg ctagggcaag gactttttta cctgtaccta
      121 attttttggc aacctcgatg gctccgtaga tagctgcagc tgaggaaatc cctacaagga
      181 agccttcttt tccaccaatt tcacgtccga gtgcaagagc gtcatctgat gttacacgaa
      241 cgataccatc ataggcttta gtatcaagtg tatcaggaat aaatccagct gagatacctt
      301 gaattttgtg aggaccaggt ttttcaccag atagaatagc agattcatct gcttctactg
      361 caaaaacttg aatgttagaa ttttctgatt tgagtgcatg agaaacacca gaaatcgttc
      421 caccagtacc tactccagca acaaaggcat ctaatccatc tttaccgaaa gcagctagta
      481 tctcagctcc tgttgttctt tcgtgtactt ctggattagc tggattgtca aattgaagag
      541 gaaggaaacc atcacgttca gcagcgattt cttgagcctt agcaatagca cctttcattc
      601 cctcgctacc aggagttagg acgagttcag caccataagc ttggataatt ttacgtcgtt
      661 ctacactcat agtttcaggc ataacgatga cgactttata ccctttagca gcacctaccc
      721 atgaaagtcc aataccggtg tttccacttg ttgcttcaac aatagtagaa ccaagtttca
      781 gaataccatc ttgttcagct ttttcaatca tgctaagggc aatacggtct tttacagatg
      841 aaccaggatt aaatgcttca agctttatat agacgtctgc agcaccttct ggcacgatgt
      901 tgttaagttt aacaatcggt gtttgaccga ttaattcagt aatgttgtta taaatagaca
      961 tatgaatacc tctttgtata agatatcttt agtataacgc tatccatacc atttgtaaaa
     1021 tatagaaatc ctatcgaagc gataggattt ctatatatca tagatcaaag tcattaattt
     1081 tcaagtgatt gcgttcagtt aattctagta aataggtgtg aaggaaaacg atatcaggtt
     1141 tcgtttgaat tgcttcattt tctagtatat tttggtacgc atctttttat tttgctcgct
     1201 aaagtagttg tgagaatgtc aacgaaacgc tgtattattc attgtttaca ctaagtttac
     1261 agaaacttca acctctcgta aaccttggtc agttaaagtg acttttccat taaaaaactc
     1321 cacaagtgca gctttaatag tttctttttc ttctttatca acataaatca tcgtatcgac
     1381 ttgatctgta aagtttgtat ccagctccat gagatcatgt tctttaagga agttactgta
     1441 ctcttggtac tgagcataag acatttgaat agcaatgcca gcctgttctt ttatttcaat
     1501 aataccaatt tctttgacag ctaaggcgac actgccggcg taagcacgaa ttagtcctcc
     1561 agcgcctagt ttaataccac caaagtagcg tgtcacgacc acacagacat tggtgagatt
     1621 gtgattttct agtaccccaa gcatgggaac accagcagta ccactaggct caccatcatc
     1681 acttgtacgt ttaatttcac tacgttctcc aataataaag gcagagcagt tatgtgtcgc
     1741 tttgtagtgt tcttttttga tggcagtaat gaagtcacga gcctcttctt cgctataaac
     1801 acgcttggca tggcagataa agcgagattt tttgatttct tcttggactt ggccgtcctc
     1861 tttaattgtc ctaaattcca tgatttaatt gtactaaaaa ataatctaaa gtgctagttt
     1921 ttacgaataa agaagtatga aagtaaattt agattatctc ggtcgtttat ttactgagaa
     1981 tgaattaaca gaagaagaac gtcagttggc ggagaaactt ccagcaatga gaaaggagaa
     2041 ggggaaactt ttctgtcaac gttgtaatag tactattcta gaagaatggt atttgcccat
     2101 cggtgcttac tattgtcgag agtgcttgct gatgaagcga gtcagaagtg atcaaacttt
     2161 atactatttt ccgcaggagg attttccgaa gcaagatgtt ctcaaatggc gcggccaatt
     2221 aactcctttt caagagaagg tgtcagaggg actgcttcaa gcagtagaca agcaaaagcc
     2281 aaccttagtt catgcggtaa caggagctgg aaagacagaa atgatttatc aagtagtggc
     2341 taaagtgatc aatgcgggtg gtgcagtgtg tttggctagt cctcgcatag atgtttgttt
     2401 ggagctgtac aagcgcctgc aacaggattt ttcttgcggt atagctttgc tacatggaga
     2461 atcggaacct tattttcgaa caccactagt tgttgcaaca acccatcagt tattgaagtt
     2521 ttatcaagct tttgatttgc tgatagtgga tgaagtagat gcttttcctt atgttgataa
     2581 tcccacgctt taccacgctg tcaagaatag tgtaaaggag aatggattga gaatcttttt
     2641 aacagcgact tcgaccaatg agttagataa aaaggtccgt ttaggagaac taaaaagact
     2701 gagtttaccg agacggtttc atggaaatcc gttgattatt ccaaaaccaa tttggttatc
     2761 ggattttaat cgctacttag acaagaatcg tttgtcacca aagttaaagt cctatattga
     2821 gaagcagaga aagacagctt atccgttact catttttgct tcagaaatta agaaagggga
     2881 gcagttagaa gaaatcttac aggagcaatt tccaaatgag aaaattggct ttgtatcttc
     2941 tgtaacagag gatcgattag agcaagtaca agcttttcga gatggagaac tgacaatact
     3001 tatcagtacg acaatcttgg agcgtggagt taccttccct tgtgtggatg ttttcgtaat
     3061 agaggccaat catcgtttgt ttaccaagtc tagtttgatt cagattggtg gacgagttgg
     3121 acgaagcatg gatagaccga caggagattt gcttttcttc catgatgggt taaatgcttc
     3181 aatcaagaag gcgattaagg aaattcagat gatgaataag gaggctggtc tatgaagtgc
     3241 ttgttatgtg ggcagactat gaagactgtt ttaactttta gtagtctctt acttctgagg
     3301 aatgatgact cttgtctttg ttcagactgt gattctactt ttgaaagaat tggggaagag
     3361 aactgtccaa attgtatgaa aacagagttg tcaacaaagt gtcaagcttg tcaattttgg
     3421 tgtaaagaag gagttgaagt cagtcataga gcgattttta cttacaatca agctatgaag
     3481 gattttttca gtcggtataa gtttgatgga gacttcctgt taagaaaagt tttcgcttca
     3541 tttttaagtg aggagttgaa aaagtacaaa gagtatcaat ttgttgtaat tcccctaagt
     3601 cctgatagat atgctaacag aggatttaat caggttgagg gcttggtaga ggcagcaggc
     3661 tttgagtatc tagatttatt agagaaaaga gaagagagag ccagttcttc taaaaatcgt
     3721 tcagagcgct tggggacaga acttcctttc tttattaaaa gtggagtcac tattcctaaa
     3781 aaaatcctac ttatagatga tatctatact acaggagcaa ctataaatcg tgttaagaaa
     3841 ctgttggaag aagctggtgc taaggatgta aaaacatttt cccttgtaag atgaggaaaa
     3901 aatttgcaaa aatagaatga aagcgttata ataaaatcat aaaaacaaaa atgtttagaa
     3961 agaaggtact catatgatta aatatagtat ccgtggtgaa aacctagaag taacagaagc
     4021 aattcgtgat tatgtagttt ctaaactcga aaagatcgaa aagtacttcc aaccagaaca
     4081 agagttggat gcccgaatta acttaaaagt ttatcgtgaa aaaacggcta aagtggaagt
     4141 aacgattccg cttggatcta ttactctccg cgcagaagat gtatctcaag atatgtatgg
     4201 ttcaattgac cttgtaactg ataaaattga acgtcagatt cgtaaaaata aaacaaaaat
     4261 cgagcgtaaa aataaaaata aggtagcaac tggtcaatta tttacagatg ctttggtgga
     4321 agattcaaat attgtccagt ctaaagttgt tcgttcaaaa caaattgatt taaaaccaat
     4381 ggatttggaa gaagcaattc tacaaatgga tttattgggg catgatttct ttatctatgt
     4441 ggatgttgaa gatcagacaa ccaatgtgat ttatcgtcgt gaggatggcg aaattggttt
     4501 gttagaggtt aaagaatctt aatttcaata tgtgtaaagg taggtttact gaattgtaaa
     4561 ctaccttttt cttataattg atagaattac tgattacact tttaaaaagt cgctttttga
     4621 ggggtattat ggtataatgg gtgccaagag gttttgaatg aaaaaatttt atgtaagtcc
     4681 aatttttcct attctagtag gattgattgc gtttggagtc ttatccactt tcattatttt
     4741 tgttaataat aatctgttga cggttttaat tttgtttctt tttgtaggag gctatgtttt
     4801 tttatttaag aaactgagag tgcattatac aaggagtgat gtagaacaga tacagtatgt
     4861 aaaccaccaa gcggaagaaa gtttgacagc tctattggaa cagatgcctg taggtgttat
     4921 gaaattgaat ttatcttctg gagaggttga gtggtttaat ccctatgctg aattgatttt
     4981 gaccaaggaa gatggtgatt ttgatttaga agctgttcaa acgattatca aggcttcagt
     5041 aggaaatccg tctacttatg ccaagcttgg tgagaagcgt tatgctgttc atatggatgc
     5101 ttcttccggt gttttgtatt ttgtagatgt atccagggaa caagccataa cagatgaatt
     5161 ggtaacaagt cgaccagtga ttgggattgt ctctgtggat aattatgatg atttggagga
     5221 tgcaacttct gagtcagata ttagtcaaat caatagtttt gtagctaatt ttatatcaga
     5281 gttttcagaa aaatacatga tgttttctcg tcgggtaagt atggatcgat tttatctatt
     5341 tactgactac acggtgcttg agggcttgat gaatgataaa ttttctgtta ttgatgcttt
     5401 cagagaagag tcgaaacaga gacagttgcc cttgacctta agtatgggat tttcttatgg
     5461 cgatggaaat catgatgaga tagggaaagt tgctttgctc aatttgaact tggctgaagt
     5521 acgtggtggc gaccaggtgg ttgttaagga aaacgacgaa acgaaaaatc cagtttattt
     5581 tggtggtggg tctgctgctt caatcaagcg tacacggact cgtacgcgcg ctatgatgac
     5641 agctatttca gataagattc ggagtgtaga tcaggttttt gtagtcggtc acaaaaattt
     5701 agacatggat gctttgggct ctgctgtagg tatgcagttg ttcgccagca atgtgattga
     5761 aaatagctat gctctttatg atgaagaaca aatgtctcca gatattgaac gagctgtttc
     5821 attcatagaa aaagaaggag ttacgaagtt gttgtctgtt aaggatgcat tggggatggt
     5881 gaccaatcgt tctttgttga ttcttgtaga ccattcaaag acagccttaa cattatcaaa
     5941 agaattttat gatttattta cccaaaccat tgttattgac caccatagaa gggatcagga
     6001 ttttccagat aatacggtca ttacttatat cgaaagtggt gcaagtagtg ccagtgagtt
     6061 ggtaacggaa ttgattcagt tccagaattc taagaaaaat cgtttgagtc gtatgcaagc
     6121 aagtgtcttg atggctggta tgatgttgga tactaaaaat ttcacctcgc gagtaactag
     6181 tcggacattt gatgttgcta gctatctcag aacgcgcgga agtgatagta ttgctatcca
     6241 ggaaatcgct gcgacagatt ttgaagaata tcgtgaggtc aatgaactta ttttacaggg
     6301 gcgtaaatta ggttcagatg tactaatagc agaggctaag gacacgaaat gctatgatac
     6361 agttgttatt agtaaggcag cagatgccat gttagccatg tcaggtattg aagcgagttt
     6421 tgttcttgcg aagaatacac aaggatttat ctctatctca gctcgaagtc gtagtaaact
     6481 gaatgtacaa cggattatgg aagagttagg cggtggaggc cactttaatt tggcagcagc
     6541 tcaaattaaa gatgtaacct tgtcagaagc aggtgaaaaa ctgacagaaa ttgtattaaa
     6601 tgaaataaag gaaaaggaga aagaagaatg aaagtaatct ttttagcaga tgttaaagga
     6661 aaaggtaaaa aaggcgaaat taaggaagta ccaacagggt atgcgcaaaa ctttcttatc
     6721 aaaaagaatc tagccaaaga agcgactgct caagctgtag gtgaacttcg tggtaaacaa
     6781 aaatcggaag aaaaagctca cgctgagatg attgcagaag gaaaagcaat taaagcacaa
     6841 cttgaagcag aagaaactgt tgtagaattt gttgaaaaag ttggtccaga tggtcgtacc
     6901 tttggctcta ttaccaataa gaagattgca gaagaattgc aaaaacaatt tggaattaag
     6961 attgataaac gtcatattca agtacaagct ccgattcgag cggttggttt gattgatgtg
     7021 ccagtgaaaa tctatcaaga tatcacaagt gtaatcaatc ttcgtgtgaa agaaggataa
     7081 gtttacacct tcttgacaag attgtaaaag gaagggaagt ctgatggcag aagtagaaga
     7141 gttacgagta caacctcaag atatcttagc tgagcaatcc gttttagggg ctatctttat
     7201 tgatgagagt aaacttgttt ttgtgcgaga atacattgag tctcgggact tttttaagta
     7261 tgcccatcgt ttgattttcc aagccatggt cgatttatcc gatcgtggtg atgccataga
     7321 tgcaacaacg gttcgtacta tccttgataa tcaaggtgat ttacagaata ttggtggctt
     7381 gtcttacttg gttgagattg ttaattctgt gccaacttct gctaatgcgg agtattatgc
     7441 taagattgtt gcagaaaaag caatgctacg tcgtttaatt gccaagttga cagagtctgt
     7501 caaccaagct tacgaagcgt cacaaccagc tgatgaaatt attgctcagg cagaaaaagg
     7561 gctgattgat gtcagtgaaa atgcaaatcg aagcgggttt aagaacattc gagatgtgtt
     7621 gaatctcaac tttggaaatc tggaagctcg ctcgcaacaa acgaccgata ttacaggtat
     7681 tgcgacaggt tatcgtgatt tggatcatat gacaacagga cttcatgagg aggagttgat
     7741 tatcttagca gctcgtccag cagttggtaa gacagcattt gccttgaata tcgctcagaa
     7801 cattgggact aagttggaca aaacggttgc tattttttca ctcgaaatgg gtgcggaaag
     7861 cttggtagat cgtatgttag ctgcagaagg cttagtggag tcacattcta tccgtacagg
     7921 gcaattgaca gatgaggagt ggcaaaaata tactattgct cagggtaatc tagctaacgc
     7981 cagtatctat atcgatgata cgccaggtat tcggattaca gagattcgtt ctcgttctcg
     8041 taaattggct caagaaactg gaaatcttgg tttgattttg atagactatt tgcaacttat
     8101 cacgggaact ggtcgagaaa atcgtcaaca agaagtttct gaaatttctc gtcagttgaa
     8161 aatactagcc aaggaattga aggttccagt aatcgctctg agtcagcttt ctcgtggtgt
     8221 agaacaacgt caggacaaga gaccggtctt gtctgatatt cgtgaatctg ggtctattga
     8281 gcaggacgct gatatcgtag cttttctcta tcgcgatgac tactatgaac gtggtggtga
     8341 agaagaggag ggtatcccaa ataataaggt ggaagttatt atcgagaaaa accgtagtgg
     8401 agctcgtgga acagtggaat tgattttcca aaaagaatac aataaatttt caagtatctc
     8461 aaagagggag gcataagatg tcagatgcat ttacagatgt agccaagatg aaaaaaatca
     8521 aagaagaaat caaggcacat gagggacaag tcgtagaaat gactttggag aatggtcgta
     8581 agcgccaaaa aaatagattg ggtaagctaa ttgaagttta tccatctcta tttattgtgg
     8641 agtttgggga tgtggaagga gataaacaag ttaatgttta cgttgaatcc tttacttact
     8701 cagatattct tacagaaaag aatttgattc attatcttga ctaaagtgag aaattttctc
     8761 actttttctt ttttctccga ataatttagg tgaaggcaat catcgcttta tattattttt
     8821 caaggaggaa gaatgaaaat tttaccgttt atagcaagag gaacaagtta ttacttgaag
     8881 atgtcagtta aaaagcttgt tcctttttta gtagtaggat tgatgctagc agctggtgat
     8941 agtgtctatg cctattccag aggaaatgga tcgattgcgc gtggggatga ttatcctgct
     9001 tattataaaa atgggagcca ggagattgat cagtggcgca tgtattctcg tcagtgtact
     9061 tcttttgtag cctttcgttt gagtaatgtc aatggttttg aaattccggc agcttatgga
     9121 aatgcgaatg aatggggaca tcgtgctcgt cgggaaggtt atcgtgtaga taatacaccg
     9181 acgattggtt ccattacttg gtctactgca ggaacttatg gtcatgttgc ctgggtgtca
     9241 aatgtaatgg gagatcagat tgagattgag gaatataact atggttatac agaatcctat
     9301 aataaacgag ttataaaagc aaacacgatg acaggattta ttcattttaa agatttggat
     9361 ggtggcagtg ttgggaatag tcaatcctca acttcaacag gcggaactca ttattttaag
     9421 accaagtctg ctattaaaac tgaaccccta gttagtgcaa ctgtgattga ttactattat
     9481 cctggagaga aggttcatta tgatcaaatt ctcgaaaaag acggctacaa gtggttgagt
     9541 tatactgcct ataatggaag ctatcgttat gttcaattgg aggctgtgaa taaaaatcct
     9601 ctaggtaatt ctgttctttc ttcaacaggt ggaactcatt attttaagac caagtctgct
     9661 atcaaaactg aacccctagt tagcggaact gtgattgatt actattatcc tggggagaag
     9721 gttcattatg atcagatact tgaaaaagac ggctacaagt ggttgagtta tactgcctat
     9781 aatggaagtc gtcgctatat acagctagag ggagtgactt cttcacaaaa ttatcagaat
     9841 caatcaggaa atatctctag ctatggatcc aataatagtt caactgtcgg ttggaagaaa
     9901 ataaatggta gttggtatca tttcaaatca aatggttcta aatcaacagg atggctgaaa
     9961 gacggttcta gctggtatta tttgaaatta tctggtgaaa tgcagacagg atggttaaag
    10021 gagaatggct cgtggtatta tctgggtagt tcaggggcaa tgaaaacagg ctggtaccag
    10081 gtctctggta agtggtatta ttcttactct tcaggcgcct tagctgttaa tacgacggtg
    10141 gatggctaca gagtaaacag tgatggagaa cgagtataga aaattggagt aggagaaatt
    10201 tcctgctctt ttctgtaagc agtttccttg acatttttct tattttgcgc tatcatatat
    10261 acatataata tatgggagtc tgtgtacagt ctgagaggaa gtgttaaact tcgaccgcac
    10321 ctgatctggg taatgccagc ggagggaacg atacttagtc taattttgca ccttttccat
    10381 gtatggtaaa ggtttttctt ttttttaaaa ggaaaacgag aagaggaggt tcttatgaaa
    10441 gcaagcattg ccttgcaagt tttaccccta gcacagggga ttgatcggat agctgttatt
    10501 gatcaggtca ttgcttatct gcaaactcaa gaagtgacga tggtagtgac accatttgaa
    10561 acggtcttgg aaggggagtt tgatgagctt atgcgcattc taaaagaagc gctggaagtg
    10621 gcagggcagg aggcagacaa tgtctttgcc aatgtcaaaa taaatgtagg agagatttta
    10681 agtattgatg agaaacttga aaagtatact gagacgacac attagtctat tgggctttct
    10741 cggagtattg tcaatctggc agttagcagg ttttcttaaa cttctcccca agtttatcct
    10801 gccgacacct cttgaaattc tccagccctt tgttcgtgac agagaatttc tctggcacca
    10861 tagctgggcg accttgagag tggctttact ggggctgatt ttgggagttt tgattgcctg
    10921 tcttatggct gtgctcatgg atagtttgac ttggctcaat gacctgattt accctatgat
    10981 ggtggtcatt cagaccattc cgaccattgc catagctcct atcctggtct tgtggctggg
    11041 ttatgggatt ttgcccaaga ttgtcttgat tatcttaaca acaacctttc ccatcatcgt
    11101 tagtattttg gacggtttta ggcattgtga caaggatatg ctgactttgt ttagtctgat
    11161 gcgagcaaac ccttggcaaa tcctgtggca ttttaaaatc ccggttagcc tgccttactt
    11221 ttatgcaggt ctgagggtca gtgtctccta cgcctttatc acaactgtgg tatctgagtg
    11281 gttgggaggt tttgaaggtc ttggtgttta tatgattcag tctaaaaaac tgtttcagta
    11341 tgataccatg tttgccatta ttattctggt gtcgattatc agtcttttgg gtatgaagct
    11401 ggtcgatatc agtgaaaaat atgtgattaa atggaaacgt acttaaaata gagcgttttt
    11461 gaaaaagaaa agaggaaatc aaaatgaaga aaacatggaa agtgttttta acgcttgtaa
    11521 cagctcttgt agctgttgtg cttgtggcct gtggtcaagg aactgcttct aaagacaaca
    11581 aagaggcaga acttaagaag gttgacttta tcctagactg gacaccaaat accaaccaca
    11641 cagggcttta tgttgccaag gaaaaaggtt atttcaaaga agctggagtg gatgttgatt
    11701 tgaaattgcc accagaagaa agttcttctg acttggttat caacggaaag gcaccatttg
    11761 cagtgtattt ccaagactac atggctaaga aattggaaaa aggagcagga atcactgccg
    11821 ttgcagctat tgttgaacac aatacatcag gaatcatctc tcgtaaatct gataatgtaa
    11881 gcagtccaaa agacttggtt ggtaagaaat atgggacatg gaatgaccca actgaacttg
    11941 ctatgttgaa aaccttggta gaatctcaag gtggagactt tgagaaggtt gaaaaagtac
    12001 caaataacga ctcaaactca atcacaccga ttgccaatgg cgtctttgat actgcttgga
    12061 tttactacgg ttgggatggt atccttgcta aatctcaagg tgtagatgct aacttcatgt
    12121 acttgaaaga ctatgtcaag gagtttgact actattcacc agttatcatc gcaaacaacg
    12181 actatctgaa agataacaaa gaagaagctc gcaaagtcat ccaagccatc aaaaaaggct
    12241 accaatatgc catggaacat ccagaagaag ctgcagatat tctcatcaag aatgcacctg
    12301 aactcaagga aaaacgtgac tttgtcatcg aatctcaaaa atacttgtca aaagaatacg
    12361 caagcgacaa ggaaaaatgg ggtcaatttg acgcagctcg ctggaatgct ttctataaat
    12421 gggataaaga aaatggtatc cttaaagaag acttgacaga caaaggcttc accaacgaat
    12481 ttgtgaaata atgacagaaa ttagactaga gcatgtcagt tatgcctatg gtcaggagag
    12541 gattttagag gatatcaacc tacaggtgac ttcaggcgaa gtggtttcca ttctaggccc
    12601 aagtggtgtt ggaaagacca ccctctttaa tctaatcgct gggattttag aagttcagtc
    12661 agggagaatt gtccttgatg gtgaagaaaa tcccaagggg cgcgtgagtt atatgttgca
    12721 aaaggatctg ctcttggagc acaagacggt gcttggaaat atcattctgc ccctcttgat
    12781 tcaaaaggtg gataaggcag aagctatttc ccgagcggat aaaattcttg cgaccttcca
    12841 gctgacagct gtaagagaca agtatcctca tgaacttagc ggtgggatgc gccagcgtgt
    12901 agccttactc cggacctacc tttttgggca caagctcttt ctcttagatg aggcctttag
    12961 cgccttggat gagatgacaa agatggaact ccacgcttgg tatcttgaga ttcacaaaca
    13021 gttgcagcta acaaccctga tcatcacgca tagtattgag gaggccctca atctcagcga
    13081 ccgtatctat atcttgaaaa atcgccctgg gcagattgtt tcagaaatta aactagattg
    13141 gtctgaagat gaggacaagg aagtccaaaa gattgcctac aaacgtcaaa tcttggcaga
    13201 attaggctta gataagtaga aaaataggga gttggtgaag attatccttt accagcgccc
    13261 tttttctttt aaaaatgaga aaatttcggt ataatagtca aacaaggtca aggtttaaag
    13321 agagaggtgg gtttgttatg agatttaaaa atacatcgga tcatattgag gcctacatca
    13381 aggcgatttt agatcaatct ggtatcgtgg agttgcaacg gagtcagttg gcagatacct
    13441 ttcaggttgt tcctagtcag attaactacg tgatcaagac acgctttacg gaaagtagag
    13501 gctacttggt tgaaagtaag cgtggtggcg gaggctacat tcgtatagga cggattgagt
    13561 tttctagtca tcatgaaatg ctccgggagc tgctttactc gattggtgag cgagtcagtc
    13621 aagaaattta tgaggatatt ctccagcttt tggttgagca ggaattgatg accaagcagg
    13681 agatgaattt gctagaatca gtagctttgg atcgcgtttt aggagaagaa gctccagttg
    13741 ttcgagcaaa catgctacgt caggtcatac aagaggtaga tagaaaaggg aagtaagatg
    13801 aactattcaa aagcattgaa tgaatgtatc gaaagtgcct acatggttgc tggacatttt
    13861 ggagctcgtt atctagagtc gtggcacttg ttgattgcca tgtctaatca cagttatagt
    13921 gtagcagggg caactttaaa tgattatccg tatgagatgg accgtttaga agaggtggct
    13981 ttggaactga ctgaaacgga ctatagccag gatgaaacct ttatggaatt gccgttctcc
    14041 cgtcgtttgc aggttctttt tgatgaagca gagtatgtag cgtcagtggt ccatgctaag
    14101 gtactaggga cagagcacgt cctctatgcg attttgcatg atggcaatgc cttggcgact
    14161 cgtatcttgg agagggctgg tttttcttat gaagacaaga aagatcaggt caagattgct
    14221 gctcttcgtc gaaatttaga agaacgggca ggctggactc gtgaagatct caaggcttta
    14281 cgccaacgcc atcgtactgt ggctgacaaa caaaattcta tggccaatat gatgggcatg
    14341 ccgcagactc ctagtggtgg tctcgaggac tatacgcatg atttgacaga gcaagcgcgt
    14401 tctggcaagt tagaaccagt catcggtcgg gacaaggaaa tctcacgtat gattcaaatc
    14461 ttgagccgta agactaagaa caaccctgtc ttggttgggg atgctggtgt cgggaaaaca
    14521 gctctggtgc ttggtcttgc tcagcgtatt gccagtggtg atgtgcctgc ggaaatggct
    14581 aagatgcgcg tgttagaact tgatttgatg aatgtcgttg cagggacacg cttccgtggt
    14641 gactttgaag aacgcatgaa taatatcatc aaggatattg aagaagatgg ccaagtcatc
    14701 ctctttatcg atgaactcca caccatcatg ggttctggta gcgggattga ttcgactctg
    14761 gatgcggcca atatcttgaa accagccttg gcgcgtggag ctttgagaac ggttggtgcc
    14821 accactcagg aagaatatca aaaacatatc gaaaaagatg cggctctttc tcgtcgtttc
    14881 gctaaagtga cgattgaaga accaagtgtg gcagatagta tgactatttt acaaggtttg
    14941 aaggcgactt atgagaaaca tcaccgtgta caaatcacag atgaagcggt tgaaacagcg
    15001 gttaagatgg ctcatcgtta tttaaccagt cgtcacttgc cagactctgc tatcgacctc
    15061 ttggacgaag cagcagcaac agtgcaaaat aaggtaaagt atgtaaaagc agacgattca
    15121 gatttgagtc cagctgataa ggccctgatg gatggcaagt ggaaacaggc agcccagcta
    15181 atcgcaaaag aagaggaagt acctgtctac aaagacttgg tgacagagtc tgatattttg
    15241 accaccttga gtcgcttgtc aggaatccca gttcaaaaac tgactcaaac ggatgctaag
    15301 aagtatctaa atcttgaagc agaactccat aaacgtgtca tcggtcaaga tcaagctgtt
    15361 tcaagcatta gtcgtgcgat tcgccgtaat cagtcaggaa ttcgcagtca caagcgtccg
    15421 atcggttcct ttatgttcct aggacccaca ggtgtcggta agaccgagtt ggccaaggct
    15481 ttggcagaag ttctctttga tgacgaatca gcccttatcc gctttgatat gagtgagtat
    15541 atggagaaat tcgcagccag ccgtctaaat ggagctcctc caggctatgt gggttacgaa
    15601 gaaggtggag agttgacaga gaaggttcgc aataaaccct attccgttct cctctttgat
    15661 gaggtagaga aggcccaccc agatattttt aatgttctct tgcaggttct ggatgacggt
    15721 gttttgacag atagcaaggg acgcaaggtc gatttttcaa ataccattat cattatgaca
    15781 tcgaacctag gtgcgactgc ccttcgtgat gataagactg ttggttttgg ggctaaggat
    15841 attcgttttg accaggaaaa tatggaaaaa cgcatgtttg aagaactgaa aaaagcttat
    15901 agaccggaat tcatcaaccg tattgatgag aaggtggtct tccatagcct atctagtgac
    15961 catatgcagg aagtggtgaa gattatggtc aagcctttag tggcaagttt ggctgaaaaa
    16021 ggcattgact tgaaattaca agcttcagct ctgaaattgt tagcaaatca aggatatgac
    16081 ccagagatgg gagctcgccc acttcgcaga accctgcaaa cagaagtgga ggacaagttg
    16141 gcagaacttc ttcttaaggg agatttagtg gcaggcagca cacttaagat tggtgtcaaa
    16201 gcaggccagt taaaatttga tattgcataa aagaataaaa gtatcagcat ctgaccataa
    16261 gtcacagtgg agtgaaactc aatgaaaatc aaagagcaaa ctaggcagct agccgcaggt
    16321 tgctcaaaac actggtttga ggttgcagat agagctgacg tggtttgaag agattttcga
    16381 agagtatgaa actaaaacct atagcttcta aacgatccgt ggttttcacc attcaacaca
    16441 aaattcatat gtttattacc ctccgtcgta tttgtcttag agcgtgtgta gtagaaaaag
    16501 agcagtctta tctgaaattt ttattctttc aaaagagacc tgtttctttt ttgcatgtca
    16561 aatccgttct agctggtatt tgaaaaatca aactaatatt caatgaaaat caaagaacaa
    16621 actaggcagc tagccacagg ttgctcaaaa cactgttttg aggttgtaga tagagctgac
    16681 gtagtttgaa gagattttcg aagagtataa gctgcaagat gaatgatttt cttgtattga
    16741 cgttgttgtt gacaaaaagt agcggataaa tgaaatccat tccattatca tagatgatag
    16801 gctggtagga aattttcaaa tagcatacag gaaatagatg tatggagttc tggtagtaga
    16861 aagggagaga gatgaacatt ttagttgcag atgacgagga aatgattaga gaaggaattg
    16921 cagcatttct gacagaagag ggttatcatg tcattatggc taaggatgga caagaggtct
    16981 tggaaaaatt tcaagatctc cctatccatc tcatggtatt ggatttaatg atgcctagga
    17041 agagtggttt tgaagtgtta aaagaaatca atcaaaagca cgatattcct gtcatcgtct
    17101 tgagtgctct gggagatgaa actactcagt cacaggtatt tgatctctat gctgatgatc
    17161 atgtgacaaa acctttttct ttggtactgc ttgtcaagcg tattaaggcg cttatcagac
    17221 gttactacgt catagaggat atttggcgat atcaggatgt aacagtggat tttacctctt
    17281 acaaagcaca ttataaaaat gaagaaattg atctcaaacc aaaggaatta ctggtactaa
    17341 agtgtttgat tcagcataaa aatcaagttt taagtagaga gcagatattg gaagaaattt
    17401 caaaagatgt agctgattta ccttgtgata gggtcgttga tgtctatatt cgtactcttc
    17461 gcaaaaaatt agctttagat tgtatcgtga ctgtgaaaaa tgttgggtat aagattagct
    17521 tatgataaaa aatcctaaat tattaaccaa gtctttttta agaagttttg caattctagg
    17581 tggtgttggt ctagtcattc atatagctat ttatttgacc tttccttttt attatattca
    17641 actggagggg gaaaagttta atgagagcgc aagagtgttt acggagtatt taaagactaa
    17701 gacatctgat gaaattccaa gcttactcca gtcttattca aagtccttga ccatatctgc
    17761 tcaccttaaa agagatattg tagataagcg actccctctt gtgcatgact tggatattaa
    17821 agatggaaag ctatcaaatt atatcgtgat gttagatatg tctgttagta cagcagatgg
    17881 taaacaggta acagtgcaat ttgttcacgg ggtggatgtc tacaaagaag caaagaatat
    17941 tttgtttttg tatcttccat atacattttt ggttacaatt gctttttcct ttgttttttc
    18001 ttatttttat actaaacgct tgctcaatcc tcttttttac atttcagaag tgactagtaa
    18061 aatgcaagat ttggatgaca atattcgttt tgatgaaagt aggaaagatg aagttggtga
    18121 agttggagaa gttggaaaac agattaatgg tatgtatgag cacttgttga aggttattca
    18181 tgagttggaa agtcgtaatg agcaaattgt aaaattgcaa aatcaaaagg tttcctttgt
    18241 ccgtggagca tcacatgagt tgaaaacccc tttagccagt cttagaatta tcctagagaa
    18301 tatgcagcat aatattggag attacaaaga tcatccaaaa tatattgcaa agagtataaa
    18361 taagattgac cagatgagcc acttattgga agaagtactg gagtcttcta aattccaaga
    18421 gtggacagag tgtcgtgaga ccttgactgt taagccagtt ttagtagata ttttatcacg
    18481 ttatcaagaa ttagctcatt caataggtgt tacaattgaa aatcaattga cagatgctac
    18541 cagggtcgtc atgagtctta gggcattgga taaggttttg acaaacctga ttagtaatgc
    18601 aattaaatat tcagataaaa atgggcgcgt aatcatatcc gagcaagatg gctatctctc
    18661 tatcaaaaat acatgtgcgc ctctaagtga ccaagaacta gaacatttat ttgatatatt
    18721 ctatcattct caaatcgtga cagataagga tgaaagttcc ggtttgggtc tttacattgt
    18781 gaataatatt ttagaaagct atcaaatgga ctatagtttt ctcccttatg aacacggtat
    18841 ggaatttaag attagcttgt agacagatta gttttttatt aaagttcata tagggttaac
    18901 ataagtgtgt tattctttgt gtagataaaa gaaaggatac taatatggta ttagcgatta
    18961 ttttagtaac attctttatt cgattgattt ttttaaagcg ttcgatagag aatgagaaac
    19021 gaatccttag caatggcggg aaagaatttg gagttgagaa tacaaaacga ttaactatgg
    19081 ctcatattgt tttttatctc tcttgcttgg ttgaggcaat ggtgcacaag acaatttttg
    19141 atggcatggg catggttggt ttagtcttgc ttattttttc tatgctgatg ttaatgttgg
    19201 tgattcactt gttgggagat atttggacag tgaagcttat gcttgtcaat aatcacaaat
    19261 atgtagatca tatcttgttt aggacagtaa aacatcctaa ttacttttta aatattcttc
    19321 ctgagttgat tggcttgacc ttgttgagtc atgcttatgt gacttttgtt ttagtttttc
    19381 cagtttatgc agttattttg tatcgacgaa tagctgaaga ggaaaagcta ttacatgaag
    19441 ttataatccc aaatggaagc ataaagagat aaatacaaaa ttcgatttat atacagttca
    19501 tattgaagtg atatagtaag gttaaagaaa aaatatagaa ggaaataaac atgtttgcat
    19561 caaaaagcga aagaaaagta cattattcaa ttcgtaaatt tagtattgga gtagctagtg
    19621 tagtagttgc tagcttgttc ttaggaggag tagttcatgc agaaggggtt agaagtgggg
    19681 atacccccaa ggttacatct agtggggatg aagtcgagtc gcatctaaaa aaaatattga
    19741 gtgagatcca aacacaatta gatagaaaac gacatgccaa aactgtagcg ctaattaaca
    19801 agttgcaaga cattaagaga acgtattcgt ataaattaaa tgttttagaa gagaagccga
    19861 aagctgagtt gacgtcaaaa acaaaagaag agttaaccgc agcttttgag caatttaaaa
    19921 aagatacatt accaacagaa ccaggaaaaa aggtagcaga agctgagaag aaggttgcag
    19981 aagctgagaa aaaagccgag gatcaaaaag aagaagatcg tcgtaactac ccaaccaata
    20041 cttacaaaac gcttgaactt gaaattgctg agttcgatgt gaaagttaaa gaagcggagc
    20101 ttgaactatt aaaagagaaa gctaagaaac ctttaaacga gggcacaatt aagcaagcaa
    20161 aagagaaagt tgagagtaaa aaagctgagg ctacaaggtt agaaaacatc aagacagatc
    20221 gtaaaaaagc agaagaagaa gctaaacgaa aagcagcaga agaagataaa gttaaagaaa
    20281 aaccagctga acaaccacaa ccagcgccgg ctcctcaacc agaaaaacca gctccaaaac
    20341 cagaaaaacc agctccagct ccaaaaccag agaatccagc tccaaaacca gaaaaaccag
    20401 ctccagctcc aaaaccagag aatccagctg aacaaccaaa agcagaaaaa ccagctgatc
    20461 aacaagctga agaagactat gctcgtagat cagaagaaga atataatcgc ttgactcaac
    20521 agcaaccgcc aaaaactgaa aaaccagcac aaccatctac tccaaaaaca ggctggaaac
    20581 aagaaaacgg tatgtggtac ttctacaata ctgatggttc aatggcgaca ggatggctcc
    20641 aaaacaatgg ctcatggtac tacctcaaca gcaatggcgc tatggcgaca ggatggctcc
    20701 aaaacaatgg ttcatggtac tatctaaacg ctaatggttc aatggcaaca ggatggctcc
    20761 aaaacaatgg
//
LOCUS       DAVAZT010000043        20574 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVAZT010000043 DAVAZT010000000
VERSION     DAVAZT010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20574
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.043"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..299)
                     /locus_tag="VQT45_001484"
     CDS             complement(<1..299)
                     /locus_tag="VQT45_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HET2359791.1"
                     /translation="MMYLDGGGVGCNWWNKRDNIAAAAVSGGMSVYQTYAIKKLIANR
                     GMMSRVVRSAITRYIGGVSMATITNALNIAATVAEVFSLGGAIAYGLDIVDGKFDG"
     gene            complement(279..347)
                     /locus_tag="VQT45_001485"
                     /pseudo
     CDS             complement(279..347)
                     /locus_tag="VQT45_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
     gene            complement(762..974)
                     /locus_tag="VQT45_001486"
     CDS             complement(762..974)
                     /locus_tag="VQT45_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000989850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359792.1"
                     /translation="MMVVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQIK"
     gene            complement(993..1352)
                     /locus_tag="VQT45_001487"
     CDS             complement(993..1352)
                     /locus_tag="VQT45_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359793.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAIYIPRWAITGAITGAAYAAL
                     AAAGGGGLQLVLASYGLRSALVAGIVKGLGVLGIHIGNAFANTVIRSIASAGIGAGAD
                     WILPILLMAGMGDVIIN"
     gene            complement(1330..1668)
                     /locus_tag="VQT45_001488"
     CDS             complement(1330..1668)
                     /locus_tag="VQT45_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HET2359794.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     EKINGTRITK"
     gene            2134..2997
                     /locus_tag="VQT45_001489"
     CDS             2134..2997
                     /locus_tag="VQT45_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2359795.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYLRQHGAGELSKHAEQVVKKLWKKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRMTILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKK
                     EVEIYYQAKER"
     gene            complement(3049..3621)
                     /locus_tag="VQT45_001490"
     CDS             complement(3049..3621)
                     /locus_tag="VQT45_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET2359796.1"
                     /translation="MKSITKKIKATLAGVAALFAVFSPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAE
                     NQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            3863..4534
                     /gene="sdaAB"
                     /locus_tag="VQT45_001491"
     CDS             3863..4534
                     /gene="sdaAB"
                     /locus_tag="VQT45_001491"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HET2359797.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            4543..5415
                     /gene="sdaAA"
                     /locus_tag="VQT45_001492"
     CDS             4543..5415
                     /gene="sdaAA"
                     /locus_tag="VQT45_001492"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HET2359798.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            5437..6069
                     /locus_tag="VQT45_001493"
     CDS             5437..6069
                     /locus_tag="VQT45_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET2359799.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            6095..6193
                     /locus_tag="VQT45_001494"
                     /pseudo
     CDS             6095..6193
                     /locus_tag="VQT45_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(6417..8267)
                     /locus_tag="VQT45_001495"
     CDS             complement(6417..8267)
                     /locus_tag="VQT45_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET2359800.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMVDFWGLSASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVARAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(8335..9474)
                     /locus_tag="VQT45_001496"
     CDS             complement(8335..9474)
                     /locus_tag="VQT45_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2359801.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKGKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDAEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGGLILKIDAHSKVTESFVMNNVAVIQQGEFVCGGPRP
                     TIVKGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLSLLTLLTLLKHK
                     NGFLIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKGTVIYLEK"
     gene            9532..10698
                     /locus_tag="VQT45_001497"
     CDS             9532..10698
                     /locus_tag="VQT45_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HET2359802.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TAMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL"
     gene            10837..11163
                     /locus_tag="VQT45_001498"
     CDS             10837..11163
                     /locus_tag="VQT45_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET2359803.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGS
                     IRHDKN"
     gene            11150..11743
                     /locus_tag="VQT45_001499"
     CDS             11150..11743
                     /locus_tag="VQT45_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HET2359804.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEVAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            11736..12647
                     /locus_tag="VQT45_001500"
     CDS             11736..12647
                     /locus_tag="VQT45_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HET2359805.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            12710..13774
                     /locus_tag="VQT45_001501"
     CDS             12710..13774
                     /locus_tag="VQT45_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359806.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEGGEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(13846..14706)
                     /locus_tag="VQT45_001502"
     CDS             complement(13846..14706)
                     /locus_tag="VQT45_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HET2359807.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHIYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTETDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPPSFYHQLDANQIEVQPILD
                     KDFKTLAQEK"
     gene            complement(14828..15814)
                     /locus_tag="VQT45_001503"
     CDS             complement(14828..15814)
                     /locus_tag="VQT45_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HET2359808.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(16086..17561)
                     /locus_tag="VQT45_001504"
     CDS             complement(16086..17561)
                     /locus_tag="VQT45_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HET2359809.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(17665..18588)
                     /locus_tag="VQT45_001505"
     CDS             complement(17665..18588)
                     /locus_tag="VQT45_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2359810.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(18602..19531)
                     /locus_tag="VQT45_001506"
     CDS             complement(18602..19531)
                     /locus_tag="VQT45_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2359811.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(19850..20200)
                     /locus_tag="VQT45_001507"
     CDS             complement(19850..20200)
                     /locus_tag="VQT45_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359812.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETADKDVLENSQEELQKAVLFLADEKGSEHTEAELI
                     DNLKEVIAKLKANA"
BASE COUNT         6253 a         4395 c         3702 g         6224 t
ORIGIN      
        1 ccatcaaatt taccgtctac gatatctaaa ccatatgcaa tggctcctcc taatgagaaa
       61 acttcagcaa cagtagccgc aatattaaga gcattagtaa tagttgccat actaactcca
      121 ccaatatatc ttgttatagc acttctaacg actcggctca tcataccacg attagcaatt
      181 aactttttaa tggcatatgt ctggtatact gacatccctc cagaaactgc agctgcagca
      241 atattatcac gtttgttcca ccagttacaa ccaacaccac ccccatcaag atacatcatc
      301 tcttcttgct caagaacaac ataattattt ggtaatacga gttccattta ttttctcctt
      361 ttttattaag catagttagg atcgtttcct aacaagtgat cgttgacttt gtttatagca
      421 cttagttacc tagataagat atcctttagc ttgcttccaa aatttaagtc tgcacctata
      481 atatgagttc atattagtac tgctaaatcc tatctatagt aatgtcaaac acctaaataa
      541 agtcatctct ccaattcatt caagaaatga agaaaggcaa aaaatcttta aaataagaaa
      601 agtgcatatt atcaggtgtt caaaaatctt gataatatgc gttatataat agaaaaattt
      661 actcaatttc actttcaaat tgagtttttt cccaacctcg tttttaattt atatcttcaa
      721 taaaatctaa tgacctagtt gatatgtcat atggaataat attatttaat ctgtaatttt
      781 tttaaaaaac ttaataataa atttgctcca ctgattgcta tcaatatttc aattggtaaa
      841 aaatagtaat tccaaataaa atgagaaatc agcaatgata gaaaaataac aatatcaatt
      901 ttcctgttgt tgacatactc tgtaatttta tggtacagga atgcaacaat aactgaaatt
      961 aaaacaacca tcataatact attatcctat tctcaattga ttatcacgtc gcccatccca
     1021 gccatcaata atattggtaa aatccaatca gctccagcac caattccagc agatgcaata
     1081 cttctaataa cagtatttgc aaaagcattt ccaatatgaa ttcctaatac tcctaaacct
     1141 ttaacaatcc cagctaccag tgcggagcgt aatccataag atgcaagaac tagttgaagg
     1201 cctccacctc ctgctgctgc taatgctgca tatgctgcac cagtaatggc tcctgtaatt
     1261 gcccacctgg gtatatatat agccccccca tcaaggtaca tcatctcttc ttcatcaatc
     1321 acaacataat tatttggtaa tacgagttcc atttattttc tcctttatac tatgtaatac
     1381 cacaaaatga ttttgaccta aatcattctt aacttgaaga atcgcaggaa atgttaattt
     1441 tggagtcaaa tcttccagtg ctactcgaac agcttttact gtaaaattca acttattcag
     1501 acctgaaaca ataccactga cagtcgttcc atacatgtct gtaccaataa tttcccgaat
     1561 cttcatgatt gatagttcct ttttgtaaga taaaagaact gttgaaacaa ctgccgcagc
     1621 acaatctgac tgatcatgtt gcatcgtaca aggatatttt tttaacatag aaatactcaa
     1681 ttctttagaa ttaatctaac ttttctttga tgtcacccaa acctcaatca ctgcccagta
     1741 gttcttgaat cagtttattt tcaatcgtat cattctttgt tcttgatatc tttccaagca
     1801 ttgtagtaca gcagattttt gtccaaggac taagcctcct ttaacaactc aagctccctt
     1861 acattatatc gaccagcccc atggaaagat tatggccaga ctaatcaatg atataataca
     1921 tactagaata caaaatattt ttttattcat actttttctc ctatctttat tttctaccta
     1981 catcatacct cttattaagc tcattttaaa attacgttaa cttttttcac aaatttattt
     2041 cgactttctt ttttactttt tacattgcta tgatacaata tttttaacaa aattttattg
     2101 tttgttaact tttttcacag aaaggagaaa atcatgcgtt atgatttcgg aaaggtctat
     2161 aaagaaatac gtgagtcaaa ggggctgacc caagaagagg tctgtggggg tgttctctca
     2221 agaaccagct tatcaaaaat cgaaagtggc aagacaaccc caaaatatga aaatatggaa
     2281 tttcttctcc gtcaaatcaa tatgagtttt gaagagtttg aatatatctg tcaactttat
     2341 caaccaagtc aacgcacaga gattatgcaa acctatctca atatgcgttc cattatcggg
     2401 accagcgatc ttgtcaattt atttcaaaaa tgccaagact acctcaagac ccaccacgat
     2461 ctccctatag aagaaatcag agatatgctt gaagttgtta tttatctccg tcaacacggg
     2521 gcaggggaac tatcaaaaca cgcagaacag gttgtcaaaa aactttggaa aaaaattgaa
     2581 aaacaagata catggtatga gagtgatcta aaaatcctca ataccattct tttcagtttt
     2641 cccattgaat acctccatct catcactgga aaaatattgc aacgcctaga agtctataaa
     2701 aactatcaac atttatatga cttgcgaatg acaattctat taaacctttc cacactctat
     2761 ctatacaatc aagataaaaa catgtgtaag caaatctgct acactttact ggaggacgcc
     2821 aagaataaga aaagctacga taggctggct atctgctatg tccgtattgg gatttgtaca
     2881 gacgattcta aacttatcca aaaagggttc tcccttctgg agctaaccga ggaaacttct
     2941 atgctgtctc atctcaaaaa agaagtagag atctattacc aagcgaagga aagataaaaa
     3001 agccgaggga tttcctcgac tctttacata ttatttgttc gttagttctt aataccagcc
     3061 attgttaagc cagaagtttt tagcagcagt ccatgaaccg taacgtcctg caacgtaggc
     3121 atctgctaca cgttcttggt tttcagctga gtagtcaccg ttcaggtatg aatctgttaa
     3181 ttggtaacgt ccgatataac gtccatttgt agctgtatag ctaccacctg attctttttg
     3241 agcgatccat tctttggctt ctgcttcaga tccgcttaca gttgaaacaa ctgtttcact
     3301 tactactgga gctgaaacag tttcatcttg agcggctggt gccgcataag tagctggcgc
     3361 tggtgttgca acaggcgcta cagggccatc gataaccaac tcttgatcaa cataaatcaa
     3421 atgaatgtta tcaatgtggt tgttttctgc caatttttca actgttgtgt tgtgagtttc
     3481 agcgatttct gaaagtgtat caccttcttt aacagtgtaa gttgatgatt cttgagcaga
     3541 tacaaatgat ggagaaaata ctgcaaacaa ggcagctact cctgcaagag ttgctttaat
     3601 ctttttagtt attgatttca tattcgaaaa ttctccttct ttctatagtt ctatcatacc
     3661 ctttaaatat tactgtttct tgacactttt atgtagaaat attacaaaat tattttttat
     3721 ttccctaaat aaggtgtttt ttgtcataaa agatactatt tttatgctat ttgaggtatt
     3781 agaaaggttt tcatccacaa ttaaagccaa gcccctcatt ctttgatata atagagataa
     3841 gaatttttat aaggggaaac tgatgaaatc acttcgtttt caatctgtct ttgatatcat
     3901 cggaccagtt atgattggcc catctagtag ccataccgct ggtgctgttc gtattgggaa
     3961 gattgtctct tccatttttg atgatactcc gacagaagtt gaattccaac tttttaactc
     4021 atttgccaag acctatcgtg gtcacggaac agacctagcc cttgttgcag gtattttagg
     4081 aatggataca gatgatcctg aaattccaaa tagtctggaa attgcccaca agcgtggtat
     4141 caagattgtc tggaccattc agaaagacag caatgcccct caccctaaca ccactaaaat
     4201 tactgttaaa aatgcccaca agaccatcag cgtgactggt atttctatcg gtggaggaaa
     4261 tattcaggta accgaactca atggttttgc cgtctctctc aatatgaata caccgactat
     4321 catcatcgtt catcaagata ttccaggtat gattgccctt gttacagagg cgctttcccg
     4381 ctatggtatc aatatcgccc agatgaatgt cactcgtgaa aaagctggtg aaaaagccat
     4441 tatgattatc gaagttgaca gtcgcaactg tgatgaggct atcgaagaaa ttcgaaaaat
     4501 ccctcatctc cacaatgtca atttctttaa ataggaggaa gcatgtttta ttctatcaaa
     4561 gaattggtcg agcaagcaga tctggacttt caaggaaatg tcgcagaact catgattaca
     4621 acagagtttg aattgaccgg tcgcgaacgt gaagaagtct tccttctcat ggaacgcaat
     4681 ctggaagtta tgaaagcctc tgtccaactt ggcctcaatg aaaataaatc tcgtagtggc
     4741 ctgacaggtg gagatgctgc caaattggat cactacatca aaaacgaaaa aactttatca
     4801 gattacacga ttctctctgc tgcccgaaat gctatcgcag tcaatgaaca caatgctaaa
     4861 atgggcttgg tctgcgctac tcctaccgca ggaagtgccg gttgtctccc ttccgttctc
     4921 actgctgcta ttgaaaaatt agacctcagc cacgagcaac aattggattt cctctttgct
     4981 gctggtgcct ttggactagt catcgcaaac aatgcctcca tctcaggtgc tgagggtggg
     5041 tgtcaagctg aagttggttc agcctctgct atgagtgctg ccgccttgac tctggctgca
     5101 ggtggaacac cttatcaggc cagtcaagct attgcctttg tcattaaaaa tatgctaggc
     5161 ctcatctgtg accctgttgc aggtttggtc gaagttccct gtgtcaaacg taatgccatg
     5221 ggagctagct ttgctttcat cgcagcagac atggccttgg caggtatcga atctaaaatc
     5281 cctgtggatg aagtgatcga tgccatgtac caagtaggag caagcatgcc aactgccttt
     5341 cgtgaaacag ctgaaggtgg actcgctacc acccctactg gtcgtcgcct ccaaaaagag
     5401 attttcggag aataagctta tcaaatagga gaaaccatga cctctatcac agcgattttt
     5461 ttcgatttgg atggaaccct cgttgatagt tctatcggga ttcacaatgc ctttacctat
     5521 acctttaaag agctgggggt gcctagccct gatgccaaaa ctattcgtgg ttttatggga
     5581 ccacctctcg aaagtagttt tgcgacctgc ctgtccaaag accaaatttc tgaagccatg
     5641 cagatatatc gttcttacta taaggcaaaa ggcatctatg aagctcaact ctttcctcag
     5701 attatagact tgcttgagga gttatcgagc agttatccac tctacatcac cacgacaaag
     5761 aatacatcta ctgctcaaga catggccaaa aacttggaaa tccatcattt ctttgatggt
     5821 atttatggtt ctagccctga agcaccccat aaggcagatg tcattcacca agccttacag
     5881 acacatcaac tagcaccaga acaagccatc atcatcggag ataccaagtt tgatatgctg
     5941 ggagctcgag aaacaggtat tcagaaattg gccgtcactt ggggatttgg agagcaagca
     6001 gatctactaa actatcaacc tgattatatc gctcacaaac ccttagaagt tttggcgtat
     6061 tttcaatagc atagactggg cgacaactct atttcagaag aaaatgaagt aatactcaat
     6121 gaaaatcaaa gagcaaacta ggaaactagc tgcgggctgc tcaaaacact gttttaaggt
     6181 tgtagatgga actgacgaag tcagctcaaa acactgtttt gaggttgtgg atagaactga
     6241 cgaagtcagc tcaaaacact gttttgaggt tgtggataga actgacgaag tcagtaacca
     6301 tatacggcaa ggcgacgttg acgtgatttg aagagatttt cgaagagtat aagtctctac
     6361 ataataaaac gcatattacc aaggttattt aacttgataa tatgcgtttt tcttttttat
     6421 tcaatgtggg ttgtttgatt agcaaaggcg ataatagctt gcttcaactc atctccactg
     6481 agagtgcgga actctccaat cttttgattg atggattcta aaggcatgac attaacctta
     6541 ccaacgaaaa tcttatccat aacttgatta tcaacgagtt cggttgatac caagagttct
     6601 tcgtagagtt tttcacctgg gcggattcca acttcaacga ttggaatttc actttcagtg
     6661 tggccactta gaagcaccat cttcttggcc aagtcataaa tcttgactgg tttgcccata
     6721 tcaaggataa agacttcccc atctttggca taagcaccag catggataac cagacggcta
     6781 gcttctggaa tggtcataaa gtaacgggtc atgcggaagt ctgtcaccgt tacaggccca
     6841 ccttcagcaa tctgacgttc aaagactgga atgacactac cacggctacc aagaacattc
     6901 ccaaaacgaa ctgcacagta ggttgattgg ctacgttggt taaagccagt gacaatcaac
     6961 tccgccacgc gcttggttgc tcccataaca tttggtggat tgactgcctt atctgtcgaa
     7021 atcataacca tcttaggcac cttggcttca tcaacggctc tagcaacatt gtaagttcca
     7081 cggatattgt ttttgaaggc ttcttttgga ttgcgctcca tcataggaac atgcttgtgg
     7141 gctgccgcat gataaacaat agcaggtttg tactgctcaa agacttgcaa caaacgatca
     7201 tagtcttgaa tgtccgcaat cacaggtaca taatcaatcc cttggaactt acgaatcaat
     7261 tcatgataaa caaggtagat tgagttttcc ccatgaccga gcaagacaat gcgttcagga
     7321 ttgaagcgac taacttgacg acagatttca gaaccgattg aacctccagc tcctgtgact
     7381 aagatggtct tacctgtcag ttctgcaccc agacgcgatt cgtcaagacg gatttcctga
     7441 cgacccaaaa ggtccgtaat atcaattttt tggaagccag tacctgcttg gtgaaggccc
     7501 tgaacaacag tttcaacctt aggcatcttg taacatttga cacccagctt attacacatc
     7561 tgcaagatac gctcatattc tgacggatcc agcgacggaa tcgcaacgat gacacgctcg
     7621 atttgatggc gtttggctaa ttcaggcaga ttgtcataag agcccaaaac aggaatacca
     7681 ccaagttttt gacccttttt cttagaatcc ttatccaaaa taccgaccag ttctaattca
     7741 ctggttggat gttggtaact atccataaag agagccccac catcaccggc accaatcaag
     7801 aaggtccgac ggtgttctcc atcaccacta ccttttttgc gtctggagta gattaactgc
     7861 caagtaatcc gtggcaataa aatcaagaag gtactcaaca agataaagag aatgataaaa
     7921 cggatggaga agagtggcaa gaaggcataa cagatactat atgacaagac actgctagca
     7981 gtcacaccaa aaaagatttt catgaaatcc gtaatcttgc tgtaacgact aatactcgcg
     8041 ctcaagcccc aaaaatcaac catcaattga tagaacagga aggccaaact cgtatagata
     8101 atgtagtcaa caggtgctgg attaatcagc ccataaaata aaatataaga tacaatgatg
     8161 gaaaccacca tactgaaaat atcaaatatt ccccagaaaa cctgcttttg ttgtttattt
     8221 aaaatttcca ccagatcaat cacataatct gtgagttttt tattcataga aatttactcc
     8281 tccttaaaat agttctacta tattgttatt atagcacatt ttaatttatt tggcttattt
     8341 ttccaaataa attactgttc ccttgtactc cttcttccat ttaaatcctc taattaaacc
     8401 tacaatcgtc ccaaggccat aagcaaagtg aatggaaaat aaaagaaagg gcatcacaat
     8461 tagaaatcca tttttatgtt ttaataaagt cagcaaagtg agtaatgaca gtaatgataa
     8521 aagtagaaaa taggcaccta atagtaaagt tatgaatacg aatgtgatcg gtaacaatgc
     8581 tagactaaac acaagactca aaacaaataa acaaggaaca taatgaaata atgataaaca
     8641 cttaaactga acatgacttg tcaagccaat ccacaaacca tttgaatact tttgatgcag
     8701 cattttcttg aatgttggtc gaatatactg ataagataga atacttgggc tatagcggat
     8761 tttataacca tgttctcgaa ttctataatg aatatcatta tcttcagttc ggccaagttg
     8821 ctcatttact aaaccaacct tctggaaaac ctctcgttta tacatcccat gaaaaataga
     8881 agaaacatat ctatcctcgg aactatttcg ataattggca atgctactgc caaacatatt
     8941 ttcctcaaca agatgcaagg tctctgccca ttttcctttt cctttgacaa tcgtcggtct
     9001 aggccctcca cagacaaatt caccttgttg aataacagcc acattgttca ttacaaaact
     9061 ctcagtaact tttgaatgag catcaatttt taaaataagg ccccctacag aatgcttaac
     9121 tcccaggtta aaaccactag cttgattttt cttaggattg ttatacaatc taattgagtt
     9181 aaactctgca tcttctttta taaattgctg aatgatagct gtggtcccat ctgtggacat
     9241 agcatttata aatagaattt caatattctc tttaggatag gtttgatttt ttaagtcttc
     9301 aattagacca ggcagatatt tttcttcatt gtatgcactg attacaatgg atacgagaag
     9361 actttcaaca ttttgagtca ctactactct cctgaatttt cccttccacc attctatcat
     9421 aattttcaag acttttccat ttttatcttg aaagccagaa accttacttg acattatagt
     9481 gaaaaagcct taaaataagc tgttattaaa atcagctaga agagatatta tatgaaaaag
     9541 caatcactct tttttgttcc aggtattatc ctgattggtg tttccttgcg aactcctttt
     9601 actgttttac ccattatttt gggaaatatt tcgcaaggtc tggaggtaga agttagttcg
     9661 cttggtgtct tgaccagcct gcctctcctt atgtttaccc tcttttcacc attttctacc
     9721 cgactggctc agaaaatcgg cttggagcat ctcttcacct acagcctctt cttcttgacc
     9781 atcggctcac ttattcgact aatcaatctg cccctgctct atctaggaac cttgatggtt
     9841 ggggcaagtg tcgcagtcat caatgtcctg cttcctagtc ttatccaagc caatcaacca
     9901 aagaaaattg gttttctgac caccttatat gtaacgtcta tggggattgc aacggctctg
     9961 gcttcctatc tagctgtgcc cattacacaa gccagttctt ggaaaggact tatcctcctc
    10021 ctcacgttac tctgtctagc aacttttttg gtctggctcc caaatcaccg ctataatcat
    10081 agactagctc cacaaaccaa acaaaaaagt caaataaagg tcatgcgtaa taaacaggtt
    10141 tgggcaatta ttatcttttc aggttttcaa tccttgatct tttacaccgc catgacctgg
    10201 ttacctacca tgtctatcca tgcaggtcta tccagtcacg aagctggctt gctgacttct
    10261 atcttatctc tgattagcat tcctttttca atgaccatcc caagcctgac aaccagttta
    10321 tctactcgca accgtcagct catgctcact ctggtttcac tagctggtgt ggtcggcatt
    10381 tccatgctct ttttcccaat caataatttc atttactggc ttgccatcca tctcctcatc
    10441 ggaaccgcaa ccagcgccct cttcccttat ctcatggtca acttttcact caagaccagc
    10501 gcccctgaaa agacagccca attgtccggc ctatctcaaa caggaggcta tatcctagca
    10561 gcctttgggc caaccctctt tggttacagt tttgacctat tccactcttg ggtaccagct
    10621 gtagctgccc tcttgctcat cgatatcctg atgactgtgg ccctctttac agtggacaga
    10681 gcggataaga tcctttaaac ttctagtttt agctagaagt tttttatata taaaaatttt
    10741 acacatttct cttgacaggg ctttctttta gatgtacaat gtatgtgtag aaaaattata
    10801 tataaaaatc ttacacatta gaaaaggagg tttcccatgt actttccaac atcctctgcc
    10861 ttgattgaat ttctcatctt ggctgtactg gagcagggtg attcttatgg ttatgagatt
    10921 agccaaacca ttaagctgat cgctaatatc aaagaatcca cactctatcc cattctcaaa
    10981 aaattggaag gcaatagctt tctgacaacc tattctagag agttccaagg tcgcatgcgc
    11041 aaatactact ccttgacaaa cggtggtata gagcagctct tgaccctaaa agatgaatgg
    11101 acactctata cagacaccat caatggcatc atagaaggga gtatccgcca tgacaagaac
    11161 tgaatacctg actcagctag aactctatct caagaaacta cctgaagctg accgtatcga
    11221 agccatggac tatttcagag agctctttga cgatgctgga gtcgaaggag aagaagaact
    11281 catcgctagt ttgggaactc ccaaagaagt ggcccacgaa gttctatcca atcttctcga
    11341 taaaaaaatc aatgaagcac ccgctcaaaa aaataaccga caaattttac atatcgcctt
    11401 gttagccctc cttgcagcac ctatcggcat tcctctggga atcgccatcc tcgtgaccct
    11461 gttcgcaatc cttgtagccg ctttgactgt cattctggct ttctttgcag tttccatact
    11521 gggtatcatc ggcggattcc tatttttagt tgaaagtttc actgtcctcg cccaagccaa
    11581 atcagccttt atcttgattt ttggttctgg tttactggct atcggtgctt cttcgctagt
    11641 tttacttggc atttcctatg tagctcgctt cttcggtcta ctcattgttc gtctggtaca
    11701 atttgttctt aaaaaaggaa agagaggtaa tcagcatgcg taaatggaca aaaggatttc
    11761 tcatctttgg tgtggtgact accgttatcg gctttatcct gctttttgta ggtatccaat
    11821 ctgacgggat taagagccta ctttccatgt ccaaagaacc tgtctatgat agccgtacgg
    11881 aaaagctaac ctttggcaag gaagtcgaaa acctagaaat tactctccac caacacacgc
    11941 tcaccatcac agactctttc gatgatcaaa tccacatttc ttaccatcca tctctttctg
    12001 ctcaccatga tcttatcacc aatcagaacg atagaactct gagtctcact gataagaaac
    12061 tgtctgaaac tccgtttctc tcttctggaa ttggtgggat tcttcatatc gcaagtagct
    12121 actctagtcg ttttgaagaa gttattctcc gactaccaaa agggagaact ctaaaaggga
    12181 tcaacatctc agccaatcgc ggacaaacca ccatcataaa tgctagcctt gaaaatgcga
    12241 ccctcaatac aaacagctat atcctccgaa ttgaaggaag tcgtatcaaa aacagtaaac
    12301 tcacaacgcc caatatcgtt aatatctttg atacagttct tacagatagt cagctagagt
    12361 caacagagaa tcacttccac gctgaaaata tccaagtcca tggtaaggtt gaactgactg
    12421 ccaaagatta tctcagaatc atcctagacc agaaagaaag ccaacgaatt aactgggaca
    12481 tctcaagcaa ctatggttct atcttccaat tcacaagaga aaagcctgaa tcaagaggta
    12541 cggaattaag caacccttac aaaactgaaa aaaccgatgt caaggatcaa ctcattgcga
    12601 gatctgatga taatattgat ctaatatcca caccaagcag acgttgacaa aaacgcttac
    12661 atctgctact atggaagcat atttatctaa ctaaaaagga ggttctacca tgaaacaaga
    12721 atggtttgaa agtaatgatt ttgtaaaaac aacaagcaag aacaagcctg aagagcaagc
    12781 tcaagaggtt gcagacaagg ctgaagaaac gatagccgat ctcgatacac caattggaaa
    12841 aaatactcaa gtagaggagg aagtctctca agctgaagtc gaactggaaa gccagcaaga
    12901 agagaaaatt gaaactcctg aaggcggtga agcgagaaca gaaatagaag aaaagaaggc
    12961 atctaattct actgaagaag agccagacct ttctaaagaa acagaaaaag tcactatagc
    13021 tgaagagagc caagaagctc ttcctcagca aaaagcaacc acgaaagagc cacttcttat
    13081 cagtaaatct ttagaaagtc cttatatccc cgaccaagct ccaaaatcta gggataaatg
    13141 gaaagagcaa gtgcttgatt tttggtcttg gctagtggaa gcgatcaaat ctcctacaag
    13201 taagttggaa acaagtatca cacacagtta cacagccttt ctcttgctca ttctgttttc
    13261 tgcatcttcc tttttcttta gtatctatca catcaaacat gcttactatg gacatatagc
    13321 aagcattaac agtcgcttcc ctgagcagct agctccttta actctttttt ctatcatctc
    13381 tatcctagta gcgacaacac tcttcttctt ttcattcctc ttgggtagtt tcgttgtgag
    13441 acgatttatc caccaggaaa aggactggac gctagacaag gttctccaac aatatagtca
    13501 actcttggca attccaatct tcctcactgc tattgctagt ttctttgctt tctttgatag
    13561 cctacgattt acggccctct tgtgtgtgat tagcattgga atcattctgc ttgccagtct
    13621 ccatatcatt acaagaccaa gtcaagcaag tgaaaccgac tccttctatc aattattctt
    13681 gtctgtcctt gtgaacggag ttattatcct cctcttcttt gtagctgaag tggcactgat
    13741 tggagattat cttcgtatct tggcctttct ttaaaattca atcctgtcat ccttggcagg
    13801 attttttcta tgtcaaaaaa gcaagtcgat tgacctgctt ctgctttact tttcttgtgc
    13861 taatgtttta aaatctttgt ctaatatggg ttgcacttct atttgattgg cgtctagttg
    13921 gtggtaaaaa gatgggggta atacctctaa gaattttgca tagtccaagc gagcaatggc
    13981 ttcatagtct tctggtttag agccatctcc tgtgatttga accaagtcaa tctcccactg
    14041 cacttcctta tccaccaatt gctcaatata ggctgcagga acaaacggtt ctctcggtaa
    14101 aactgtcttg actccttgag ctagatggta aacgccatgc acttttcctt ctccatcctg
    14161 atagaaggaa actctcgcaa agtaggcatc tgtctcttga accgcacgca cacgcgcttc
    14221 aaactgagcc aaaccatctg cctctaaaaa gcttttcaag ttctcacgac taaagaaaat
    14281 aggattaaaa attccttggc aaatcgtaaa acgagctaca gggtctgcta gataggcttg
    14341 aatacttgct tggaaataag cttcaaaatc aaaaccatct agcccttcaa tatcagtccc
    14401 tgtataagca agcaaagcat ctaaaaatga cttgataatc tgccagtctg tctctgttag
    14461 taggtcagga agatcgacac ggtaagcctt ttgaccatca gcataactga ccttaaaaag
    14521 aaattgtgat tgccccacta tcgcacactc aatatactcg agacgattaa gaggctgacg
    14581 gagatagact acatcataga tatgtgactc caaaccgtct agcaatgcca agatcgactt
    14641 ggcattcaaa atctcttgtt ctcctaaaat gctctgttta tttggaataa aaaatgtttt
    14701 cgccataact ggactccttt gaaatcgctt acatacagta taccttattt ttctgaaaga
    14761 tacagaaaca aactttagat ttttgagtac aaagcataga aaaacagccc ctgaggactg
    14821 tttgatctta tacagtagct gcttgatcca agctttcacc gatagcggct aggcgctcga
    14881 tcacttcagc ttgtgtcaat tcattttttg aaacatagcg gttacgtggg tgaacacggc
    14941 actcgtgtga gcatccacga aggtacttgt cttcattttc ttctgatgtc aagatacgac
    15001 ggttacagaa gggatttcca cagttgacat aacgttcaca tggtgttcca tcaaaccagt
    15061 ctttccctac gatggttggg ttgacatggt tgacatcaac ggcgatacgc tcgtcaaata
    15121 cgtacatttt tccatcccaa agctcacctt gaacttctgg gtctttaccg taagttgcga
    15181 ttcctccgtg caattggccg acatctttgt agccttcacg gaccatccag cctgagaatt
    15241 tctcacagcg aacgccacct gtacagtaaa ccacgacacg cttgtccatg aatttttcct
    15301 tgttatcacg gacccattgt ggtaactcac ggaagttgcg aatatctggg cgaatagctc
    15361 cacggaaatg tcctaggtcg tactcataat cgttacgtgt gtcaaggaca acggtatctt
    15421 tatcaagaag cgcttctttg aactcttttg gagacaagta agcacctgtt gtttcaagtg
    15481 ggttgatgtc attgtcaaag tcgttgtctt ccaaaccaag gtggacaatt tctttcttgt
    15541 agcgaacaaa catcttcttg aaggcttgtt cattttcttc gtcaatcttg aaccagagtt
    15601 cttccattcc tggaaggctg tgaacgtagt ccatgtattt ttgagttgtt tcatagtcac
    15661 ctgaaactgt tccgttaatt ccctcgtcag cgactaggat acggccttta agaccgattg
    15721 atttacagaa agccaagtgg tctgcagcaa attgctctgc attttcaatt ggagtataaa
    15781 ggtagtaaag taagacacga atatcttttg ccataagatt tgttctcttt tctattctta
    15841 aattttctaa attttttatt tatccatact agtatacctg cttgagaaaa cgaatgcaat
    15901 ttatttgact ggaaattgta gaggattctc gaaatttcct gaatggttaa aataaggaca
    15961 agagaaaaca tggatatcta tatccttgtg ccaaaaaaac cactgccctc cccagaccaa
    16021 cctgaggaaa gcagtgattc ttattttagg agttaggaat gaatacacga aatcaattta
    16081 gctgattatt ttttgttttt caagaattca tcgtattgtt tttgcatttc gttcaatact
    16141 ttttcgtagg caccttcaga tttcaatttt tccatcaatt ctggaatcgc tttatctggg
    16201 tctacagtac cagtgttgat agctgtatca aattgttgca ttgtgttagc aatagctgag
    16261 atttcagatt tcacattgtc agtattgaag ataaatccaa gcgctggaga ttctttagct
    16321 tctgccaatt ctttcttaga attttcgatt tgttggtctg taacgttttc gttgatgtaa
    16381 aggatccagt tgttaccagt gttccatcca cccatgtgag tgtttccttt gtagccatca
    16441 agaacgcgaa cacggttttc tttaccttca attttttccc agttcttgcc ttctggaccg
    16501 taaacaagac cgttcaaaag ttctgggttc gtattcaaga ggttcaagat ttccattgat
    16561 ttttctttgt tcttagagtt gtttgagatg acaaagttag caacttgtgt tgtttggttt
    16621 ttcttgatga agttagtgat tggtttgatt tggatatctt tgttggcaac acgtgaaagc
    16681 aagctgttac cgtagtcagc tggtcctact gtttcttcac gaacgaacca agtatcttgt
    16741 tgaaggtcaa atgaagtatc gcttgttgcg acgtcttttg gaatgtagcc agcttcatag
    16801 aatttgtgaa gagtcttcaa gtgttctttg aaacgaggca cttcgtaacg gtttacaact
    16861 ttagtagtat cgccttcaag gtcaataacg aatggaagcc cgtttgctac tgggtagtca
    16921 aaattatcag atgggatgaa aactttacca atagcaaatg gtactacgtc tggagctttt
    16981 tctttgattt gtttcaagac tggctcaaga gtttcgtaag aagtaacacc tgaaatatcg
    17041 ataccatatt tggcaaggag agttccgttg aaggcaaagt tttgagatga tgctacgttg
    17101 gctgcaactg gtacagcata aatcttacca tttacagtat tacccttgat ataagctgga
    17161 tcaagtgcct tgtaaaggtc tttaccttct tttttgtaca attctgtcaa gtcagcataa
    17221 gcaccttttt gagcatttac aatatagtta tctgcaaagg cgatatcata gttttcacca
    17281 gatgatgtga taactgacat tttcttacca tagtcacccc agccaaggta ttggatatcc
    17341 aatttggcac caactttttc ttcgatgatt ttgttggcat ttgctaacaa ttcatccaag
    17401 ttatctggtt tgtcaccgat ttggtacatt ttgataacag gtttgtcacc tgaatcagca
    17461 gcttttttgc tgttacctgt caaatttcca caagcagcaa gacctgcagc cagagcgact
    17521 acactagcag atgcaaaagc atattttttc cagtttttca tgataaaaac tccttttttt
    17581 atttttaaac ttataaacaa tgtaatgatc ttaacttcac acaagggaag ttgggaactg
    17641 agaaatgttc tttttcaata agcactattc tttcacacca ccgatagtca aaccttttac
    17701 aaagtagcgt tggaagaatg gatacaaaat cgcgattgga agggttgcta ccacaaccat
    17761 ggccatacga cctgtttctt tcggtagagc aactcccagt tgaccagtca agccgaccgc
    17821 tttggcaatg tagtccatat tttgttggat ttgcatgagc aaatattgca atggatacaa
    17881 gttatcactc ttgatgtaaa gaagggcgtt gaaccagtca ttccagaaac caagagctgt
    17941 caaaagcgtg atggttgcga tacctggtag tgacaatggc aaacagattt ggaagaaaat
    18001 ccgagcctca ctggcaccat cgatacgagc cgattcgaga atggcttctg gaatggtctt
    18061 cttgaaaaaa gaacgcatca agatgatatt gaatggtgag agaagcattg gaacaatcaa
    18121 ggcccaaaca gtgtcaccaa gctgaagtac acgggtcacc atgatataac ctggtaccaa
    18181 accagcgttg aacaacatac tgagaaggac gaagatggta aaaaatctgc gatacttaaa
    18241 ggttgtccgt gaaatagcgt aggcataggt tgttgtgata aagacatttg tcaatgtccc
    18301 aactacggtt acaaagacag agatgaagag ggcttgtagg attttatcct taaactgtgc
    18361 caaaaactca aaaccgtcta agccaaattg ggatgggaag aagctatagc cgtattggag
    18421 gaggcttttc tcgtctgtca ctgaaataat gataacgaat acaaaaggta ggatacaaga
    18481 gagggcaatc aaacccgaaa tgatactgaa gaagatatct gctttcttac tgaaggagtg
    18541 aatgccgaca ttatcaattt tttctttttt aattttcttt tttgccatat tctcctcctt
    18601 tctagaacaa agctgagttt ggatcgactc gtcttgcaag caagtttgat aggataacca
    18661 gaatcaaacc aacaacggat tggtaaagac cggctgctgc agccataccg atatctgctg
    18721 tctgagtcaa accattaaag acatatacgt ccaaaacgtt ggttacattg taaagctgac
    18781 cagcattgtg tgggatttga tagaagagac cgaagtctgc gcggaagata tttccgactg
    18841 caaggatggt caatacagtt acaagcggag tcaactgagg aatggttacg ttgcgaatac
    18901 gttgccactt gctagctccg tccactgtcg ctgcttcgta gtaggttgga tcaattccca
    18961 tgatcgtcgc atagtacatg acactgctat atccaaagcc tttccaaata cctaggaaaa
    19021 gtaggagata gggccagatg cccaggtcag cgtagaaatt gacttctttg agaccaagac
    19081 tttccaatag atgattgaac acccctttat caatatttag gaaggcatct gtaaagaaac
    19141 tgatgataac ccaagacaag aagtaaggga acaacataga agtttgaaaa atcttcacca
    19201 ttctcttaga acggagctcg ctgaggataa tggcaatccc tacagataca actaaaccta
    19261 gaaagataaa gccaagattg tagaggacag tatttcgtgt gataataaag gcgtctcttg
    19321 aactaaataa gaatctgaaa ttatcgagtc cgacccattt actatttatg atactatcta
    19381 tgaaaccatt actggtcatg tggtagtctt tgaaggcaac cacgttccca aatactggaa
    19441 tgtaaaagaa tagaatcaac cagagtgccc ctggcaaaac catcaagaga aagatccagt
    19501 tgtctctcaa tgtttttgaa aactttttca taatttcctc cctttttatt ttgatatcca
    19561 tctaaaaatt cttttttaga cttttgataa cgattacatt attagtatac tcctatttgc
    19621 aggttaggtt aaactcctaa ttatagaaaa aactccacaa attatgtagc agatttaaaa
    19681 ctttatcacc actatcaaac aaatgtccta aatcaattgt ttattttatc tctattagcc
    19741 cagtgatggc gtcactctgt tataagcatc caacaacggg gtatactgaa aaatctccag
    19801 actagggaac tcagcgatag ttcctaatct ggagattttt aatatgttat taggcgtttg
    19861 ctttcaactt agcaataacc tctttaagat tatcaatcaa ctctgcttca gtatgctcag
    19921 agcctttttc atctgccaag aacaaaactg ctttttgaag ttcttcttga gagttttcaa
    19981 ggacatcctt atctgctgtt tctttgcccg ctgtttgtcc tccatcctta gttgctgact
    20041 ggctttcctt aatggactct agggaagcaa tggcatcttt gactgtttgc aagatatcac
    20101 gtaaaccttg ctctgtcaaa ctatcatctg caaaagcttt cttagcctct gccaaaacca
    20161 gacgtgctga atctgtggta ggattcgata cacctgtcaa tgatctcaaa agattttcta
    20221 aagtttgagt ctgcttacta atactagact aaaatcaaaa agcattatat aacagtgata
    20281 tgaaatcaac taaagaagaa atccaaacta tcaaaacact tttaaaagac tctcgtacag
    20341 ctaaatatca taaacgcctt caaatcgttc tatagtaaaa tgaaacaaga acaggacaaa
    20401 tcgatcagga cagtcaaatc gatttctaac aatgttttag aagtagaggt gtactattct
    20461 agtttcaatc cattatattt cgtctgatgg gcaaatctta taaagagatt atagaacttt
    20521 tatagtagtt tgaaataaga tgtgaacaac tctatcagga aagtcaaatt aatt
//
LOCUS       DAVAZT010000044        19046 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVAZT010000044 DAVAZT010000000
VERSION     DAVAZT010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19046)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19046
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.044"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            1..283
                     /locus_tag="VQT45_001508"
                     /pseudo
     CDS             1..283
                     /locus_tag="VQT45_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            201..629
                     /locus_tag="VQT45_001509"
     CDS             201..629
                     /locus_tag="VQT45_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET2359813.1"
                     /translation="MSKSTSKRYYQVAIPFTRLFCLVLVSIDYINCLSETADKNWHKS
                     DRIFVTNTGKTVHSSILSKSLQRANERLKKPIPKHLSPHIFIHITISILSENKIPLKT
                     ITDRVGHPDSEVTNSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(1121..1531)
                     /locus_tag="VQT45_001510"
     CDS             complement(1121..1531)
                     /locus_tag="VQT45_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001124848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359814.1"
                     /translation="MPKKKIERISVIHREKILWLKWYFMRDKEKPKYSVLECKMFDAA
                     KNKDMLAYKKYATIKQITDIRVQTSEDDILTAIKEVYVYNHMNVIGACQRILFVSQSP
                     AYNKLNKWFETYSDLYFSIIPLPNMGAYHELVDS"
     gene            complement(1549..1926)
                     /locus_tag="VQT45_001511"
     CDS             complement(1549..1926)
                     /locus_tag="VQT45_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359815.1"
                     /translation="MRKYLKEIKELQELKELLSSRNTPEVIIVEGNDDLGEFFQVDGE
                     LFSDIELLENLKKWREWEVQVIVDDWCNRGLNEYETGILYFPKHEDKMDYIRFNKGLE
                     PLYHALDEPYTTISKSEWLKLLD"
     gene            complement(1868..2296)
                     /locus_tag="VQT45_001512"
     CDS             complement(1868..2296)
                     /locus_tag="VQT45_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000918209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HET2359816.1"
                     /translation="MAGNENDGLTSKQIKFIDAMLTEPTIDKACQKAGVSRATGHKYL
                     KVAAVKKTLRLKQDEMMDKTTQMLYLASSNAVSVLNDIMMDAKINPFIRTQAAKTILE
                     QSYKTHEIFGVVRQIEELRLEIEEVSKGDQRVTRTQGIIK"
     gene            complement(2340..2945)
                     /locus_tag="VQT45_001513"
     CDS             complement(2340..2945)
                     /locus_tag="VQT45_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359817.1"
                     /translation="MTFTTIKDDIKAFGKKKHGYMTGYIAKQEELHKQLQNGMIGEKY
                     AKDQLEAYKLEGDTYSRDTYNKIHAEIEKQHDLELEALKEKELSVTADDVAELTLLAS
                     MKMTKDELLGYFEKYKNKPLAIKKLWSIAEQYPEIAINLELFNAEQALESLILFFKRQ
                     LSYCHYSLLINGDKIQAVTTEMVVNSDAPELDRRLDEYLNK"
     gene            complement(3035..3208)
                     /locus_tag="VQT45_001514"
     CDS             complement(3035..3208)
                     /locus_tag="VQT45_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359818.1"
                     /translation="MTENKDNKLLEMMEKGFVLYSKNGIIKYIEIPDHGSIKLKAQDG
                     QLVYKEVTTGEQC"
     gene            complement(3807..4703)
                     /locus_tag="VQT45_001515"
     CDS             complement(3807..4703)
                     /locus_tag="VQT45_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET2359819.1"
                     /translation="MKSLQSSLGNIETFKLDELCPKHEIQLTQIKGERHVVVGWNENG
                     EVIKEVRCIPPYCEQCQEEQKKQDEEDAIADNLNAKLYLQTYNVLMSNKSYVADEFKT
                     KTFDDFNAVTSEEKRFLEFAKGQVQKYLDGMRGNTLITGGTGIGKTLLSVAIAKGINE
                     GYKTKGEPKSVLFVSLTEMIKQIKEGWNYGKGATLTEFEATELMKSVDYLIIDDLGAK
                     NAVIKPKSDWEQDLLFDVLNNRENTIFNTNLDSDELKIVYNERNYSRILKGLEGNTFK
                     AFTIKDKRYSINQLKNKVKQLK"
     gene            complement(4715..5524)
                     /locus_tag="VQT45_001516"
     CDS             complement(4715..5524)
                     /locus_tag="VQT45_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HET2359820.1"
                     /translation="MAKTKVYFWLKIDKKFFDNIFIKRLKTVPGGYTMTVIYIRLMLE
                     SLESDCILYYEGYFNNLKEELALKLDVSEDDIDMTMAYFTKCGLIQIDEDKNAELPQA
                     KAMVMSETNWASYKREQRKKGKLEEVQPSLTFSNSCPTEIEKELEIEVDKEQSPTPST
                     INQDFVNLYKSFEAETGKALSPLQIQELQYMLEDFSPELIHEALKEAVSQGKANFAYI
                     KAILNRWKQDNLLTVELVRNSRAAREAKKQQTNQLEPTSYEDWIPTQEKPF"
     gene            complement(5599..5814)
                     /locus_tag="VQT45_001517"
     CDS             complement(5599..5814)
                     /locus_tag="VQT45_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359821.1"
                     /translation="MNELDISNTQAVFVTVILIGLLLYLNHRDRKKSAQLERENQQTI
                     ETPSEDLNPDYGRYIQLAGVDVWGRIE"
     gene            complement(5816..6016)
                     /locus_tag="VQT45_001518"
     CDS             complement(5816..6016)
                     /locus_tag="VQT45_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359822.1"
                     /translation="MTLDLDNMTQAEFDEAMAEIQLQSPNIFQLISDFVNKKVTSVEI
                     DDLLNMKRAEQVAYIKNYKARA"
     gene            complement(6013..6204)
                     /locus_tag="VQT45_001519"
                     /pseudo
     CDS             complement(6013..6204)
                     /locus_tag="VQT45_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841301.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6193..6483)
                     /locus_tag="VQT45_001520"
                     /pseudo
     CDS             complement(6193..6483)
                     /locus_tag="VQT45_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424675.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
     gene            complement(6653..6805)
                     /locus_tag="VQT45_001521"
     CDS             complement(6653..6805)
                     /locus_tag="VQT45_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359823.1"
                     /translation="MKIVTFKPTKQIDGGFYLPGIDILFVSDKADAKSTEDVILFISR
                     NGLNKS"
     gene            complement(6816..7082)
                     /locus_tag="VQT45_001522"
     CDS             complement(6816..7082)
                     /locus_tag="VQT45_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359824.1"
                     /translation="MEILSKEIQLQGLQLLKQTLETLVELEKQRSSKLDLISRKELMD
                     LLGISATTLDNWEDLALKRYQTPMDGAKKVFYRLSDVYLFLAIK"
     gene            complement(7293..7475)
                     /locus_tag="VQT45_001523"
     CDS             complement(7293..7475)
                     /locus_tag="VQT45_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET2359825.1"
                     /translation="MLITLSLAEKVRIKRARLQLTKKAVSEQLGIKSQTLTKVENGNY
                     DASKRIYESVMTWLVE"
     gene            7537..8040
                     /locus_tag="VQT45_001524"
     CDS             7537..8040
                     /locus_tag="VQT45_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2359826.1"
                     /translation="MYKMNRIKQLRKENNLTQRELANETKIPYRTIQRWENGETDIKS
                     DAAQVLADYFGVSIPHLLGYSDLIADTDSDIKAMAYSHLLTFVDEKQIKEFEKEFIRA
                     NDNSDTFGDLGSGEKALEKYYQALCYLVPPFRDILARYSFLSLDEKKSVYNIIVGLSN
                     NLSKENK"
     gene            8114..9277
                     /locus_tag="VQT45_001525"
     CDS             8114..9277
                     /locus_tag="VQT45_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET2359827.1"
                     /translation="MNIIEKIKKNGQRVYYASVYLGVDQLTGKKARTTVTATTKKGVK
                     VKARDAINTFAANGYTVKDKPTITTYNELVKVWWDSYKNTVKPNTRQSMDGLVRVHLL
                     PVFGDYKLSKLTTPILQQQVNKWADKANKGEKGAFANYSLLHNMNKRILKYGVAIQVI
                     QYNPANDVIVPRKQQKEKAAVKYLDNKELKQFLDYLDTLNQSNYENLFDVVLYKTLLA
                     TGCRISEALALEWSDIDLESGVISINKTLNRYQEINSPKSSAGYRDIPIDKATLLLLK
                     QYKNRQQIQSWKLGRSETVVFSVFTEKYAYACNLRKRLNKHFDAAGVTNVSFHGFRHT
                     HTTMMLYAQASPKDVQYRLGHSNLMITENTYWHTNQENAKKAVSNYETAISNL"
     gene            complement(9431..10735)
                     /gene="eno"
                     /locus_tag="VQT45_001526"
     CDS             complement(9431..10735)
                     /gene="eno"
                     /locus_tag="VQT45_001526"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HET2359828.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            10899..11345
                     /locus_tag="VQT45_001527"
     CDS             10899..11345
                     /locus_tag="VQT45_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HET2359829.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(11342..12457)
                     /locus_tag="VQT45_001528"
     CDS             complement(11342..12457)
                     /locus_tag="VQT45_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HET2359830.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIDVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGRHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(12466..12795)
                     /locus_tag="VQT45_001529"
     CDS             complement(12466..12795)
                     /locus_tag="VQT45_001529"
                     /inference="COORDINATES: protein motif:HMM:NF019887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HET2359831.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGGNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(12749..13111)
                     /locus_tag="VQT45_001530"
     CDS             complement(12749..13111)
                     /locus_tag="VQT45_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HET2359832.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHC"
     gene            complement(13170..14603)
                     /gene="glgA"
                     /locus_tag="VQT45_001531"
     CDS             complement(13170..14603)
                     /gene="glgA"
                     /locus_tag="VQT45_001531"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HET2359833.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(14600..15739)
                     /gene="glgD"
                     /locus_tag="VQT45_001532"
     CDS             complement(14600..15739)
                     /gene="glgD"
                     /locus_tag="VQT45_001532"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HET2359834.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTFLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVRTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(15729..16871)
                     /locus_tag="VQT45_001533"
     CDS             complement(15729..16871)
                     /locus_tag="VQT45_001533"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HET2359835.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(16861..18789)
                     /gene="glgB"
                     /locus_tag="VQT45_001534"
     CDS             complement(16861..18789)
                     /gene="glgB"
                     /locus_tag="VQT45_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HET2359836.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEYGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAIVTELPDKKWRDGLWLARRKRWGFAERPVNIYEVHAGSWKRNPDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDIYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEVIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         5656 a         3987 c         3208 g         6195 t
ORIGIN      
        1 gatgacgagc gacttttttg aagcttggtt tcagaagttt ctcttaccaa cattaaccac
       61 accatcggtt attattatgg ataatgtaag attccataga atggggaagc tagaactctt
      121 gtgtgaatag tttgggcata aacttttacc tcttcctccc tactcacctg agtacaatcc
      181 tattgagaaa acatgggctc atatcaaaaa gcacctcaaa aaggtattac caagttgcaa
      241 taccttttac gaggctcttt tgtcttgttc ttgtttcaat tgactatata aattgtctaa
      301 gcgaaacagc cgataagaat tggcacaaaa gcgaccgtat ttttgttacc aatacaggaa
      361 aaacagttca tagttctatc ttgagcaagt ctctccagcg agcaaacgaa cgccttaaaa
      421 aaccaattcc caaacatctg tcccctcaca tcttcataca catcactatt agcatcttat
      481 cagaaaataa aattccttta aaaacaatca cggacagggt tggtcatccc gactctgaag
      541 tcactaattc catctacacc cacgtcacaa agaacatgaa agatgaagca atcaatgtac
      601 tggataaagt tatgaaaaag attttttaaa aagttttgtc ccttttttgc cctctaaata
      661 caaaaatagc ccttcggata aaatccgagg ggctagaaac gttgttaaat caacggccga
      721 acttttgaat ttcatggttc gggataaaat agttcactga actattttat tttttaaggt
      781 tatcataata tcaaatagtt caattaaata cgctaaatta ctaatatact ttttaccttt
      841 ttcattctaa aatgtaaagt acaaacaatt acaatatact agagggggag taaaaaaggt
      901 aataaaattg acgagttcag caggcaaggg aaatagcact tttcatggtg ttattttttt
      961 aattcagcaa tggagtagcc gcttaattga tagaaacaaa aagcacctag tttcctagat
     1021 gctagcacaa tagcccggat tcgaaccgga atctcctcaa ttaaggtgca atccctatat
     1081 actactcatt gtgctttggt tcattatatc atacaatcaa ctagctatct accaactcat
     1141 gatacgctcc catattcggt aatggaataa tactaaaata caaatctgag taagtttcaa
     1201 accatttatt cagcttgtta taggctggcg actgactaac aaataatatc cgttgacaag
     1261 ctccgataac attcatgtga ttatacacat agacctcttt aatggccgtt aaaatatcgt
     1321 cttcacttgt ctgtacccta atatctgtta tctgcttaat cgtagcgtat tttttataag
     1381 ctagcatatc tttattttta gcagcatcaa acattttaca ctcaagaaca ctatacttag
     1441 gtttttcttt atctctcatg aaataccact tgagccataa aattttttct ctgtgaatta
     1501 ctgaaatacg ttcgattttt ttctttggca tgattacctc ctaaattatt aatctaatag
     1561 ctttaaccac tcactttttg agattgttgt ataaggttca tctagcgcgt gatataaagg
     1621 ttctaaacct ttgttaaatc ggatatagtc cattttatcc tcatgctttg gaaaatataa
     1681 gattcctgtt tcatattcat ttagaccacg gttacaccaa tcatcaacga taacctgcac
     1741 ttcccattca cgccactttt taaggttttc taaaagttca atatcactaa ataactcacc
     1801 atcaacttgg aaaaattctc ccagatcatc gttaccctcg acgatgataa cttcaggcgt
     1861 atttctacta cttaataatt ccttgagttc ttgtaactct ttgatctcct ttagatactt
     1921 cctcaatttc taacctcaat tcttcaattt gtcttactac tccaaaaatt tcatgagttt
     1981 tatatgattg ttcaagtata gtttttgctg cttgagttct tataaaaggg ttaattttgg
     2041 catccatcat aatatcattg agtacagaaa cagcattgga tgaggctaga tatagcatct
     2101 gtgtagtttt atccatcatc tcatcttgtt ttagtctcaa tgtcttttta acagctgcaa
     2161 cttttagata cttatgccct gttgcccttg acacccctgc tttttggcac gctttatcta
     2221 tcgttggctc agtaagcatg gcatctatga attttatttg tttagatgta aggccatcat
     2281 tttcatttcc tgccatctat tacctcctcg ttatcaaaat aaaggggttg ctagcccctc
     2341 tatttgttta aatactcatc caaacgacgg tcaagctcag gggcatctga atttactacc
     2401 atttcagttg ttacagcttg gattttatcg ccgttgataa gcaaactgta atgacaatat
     2461 gaaagttgcc gcttaaagaa taagattaga ctttctagcg cctgctctgc attgaataat
     2521 tccaagttga tagcaatttc tggatattgt tcagcaattg accaaagttt tttaatagca
     2581 agaggtttgt tcttgtattt ttcaaaataa cctagcaatt catcctttgt catcttcata
     2641 ctagctaaca aggtcagctc tgccacgtca tcagctgtta cgctgagttc tttttctttt
     2701 aatgcctcta gctctagatc atgctgtttt tcaatttctg catgaatttt attataggtg
     2761 tccctagaat aagtgtcccc ctctaactta taagcctcta gctggtcttt agcgtatttt
     2821 tcgcctatca taccattttg taactgttta tgtaattcct cttgtttagc aatgtagcca
     2881 gtcatgtacc catgcttttt cttgccaaaa gccttaatat catccttgat tgttgtaaat
     2941 gtcatgttat cctccttacg aaaaaataaa agaggtatga caaaagagcg ttaaactcaa
     3001 ttatcatacc tctggttttt ccagtcagta tttattaaca ttgttctcca gtggtcactt
     3061 ccttataaac taactgccca tcttgagctt ttagcttaat gctaccatga tctggaattt
     3121 caatgtactt tattatacca ttttttgagt ataaaacaaa gcctttctcc atcatttcta
     3181 ataatttatt atccttgttt tcagtcatga atttctcctt tatttcaagt gtcccaacgg
     3241 gtacggttgt aagctgagac attttagggc tatctttgag cgacaaaaat gtcgaaaagt
     3301 cttcagttcc tgtataaccg ttattagttt tgtttgctac tcatttttga gtcacaaatc
     3361 tgttaagcaa aaatgagtaa tagctcgtaa gataagtaaa tctaatactt gtattcctaa
     3421 agcgttgata taactgatat tttcaactat ccaacgctct ttactaccct ttttagtgtg
     3481 ctttagctca tttttgagct tttttgagct tttttgagtt ccattttggg aatgcaaagc
     3541 aggcgcgcac cgtgcatgct tttttcttgc tcatagcctc accctcagaa gtttgccgac
     3601 cgagagcgtg gggcttttta tttttgtata attaaaaaca gctgcacaat ttttgtacag
     3661 ctacgaccga ggcaggggcg acctgccgta ctttacacta gataatatca tctaggtagt
     3721 ccaactgtat tttatcatat taaaggctac attacaattt ctcaccctgt gaagagtgtc
     3781 tatttttgtt taggtttgta agtcgattac ttcaactgct ttaccttatt ttttaactga
     3841 ttaattgagt atcgcttatc tttgattgtg aaagccttaa aagtgttacc ctcaagacct
     3901 tttagaatac ggctataatt ccgctcgttg tatactatct tgagttcatc gctatcaaga
     3961 tttgtattaa atatagtatt ttctcgatta ttcagtacat caaaaagtaa atcctgctcc
     4021 caatcgctct taggtttaat aacagcattt tttgcaccta aatcatcaat aattaagtaa
     4081 tcaacagact tcatgagttc agtagcttca aactctgtaa gtgttgcacc tttaccataa
     4141 ttccacccct ctttaatttg tttgatcatt tcggttaggc ttacaaaaag cacactctta
     4201 ggttctcctt ttgtcttata cccctcattt atacctttgg caatagcaac tgataaaagt
     4261 gtttttccaa tccctgtacc tcctgtgata agcgtatttc ccctcatgcc atcaagatat
     4321 ttttgtacct gaccttttgc aaattctaaa aatcgctttt cttctgatgt tacagcatta
     4381 aaatcatcaa aagttttagt tttaaactca tctgctacat agctcttatt gctcatcaac
     4441 acattataag tttgcagata tagtttagca ttcaaattat cagcaatcgc atcttcttca
     4501 tcttgctttt tctgttcttc ttggcattgt tcacaatagg gtgggataca gcgaacttct
     4561 tttattacct ctccgttctc attccacccc actactacat gtctttctcc tttgatttgt
     4621 gttagctgta tttcatgctt aggacacaat tcgtctagtt taaatgtctc aatatttcct
     4681 aaactagatt gtaatgattt cattttctga cctcctaaaa tggtttttct tgtgttggta
     4741 tccaatcttc atagctggta ggctctagtt gattggtttg ctgtttttta gcctcacgcg
     4801 ctgccctgct atttctaaca agttccaccg tcaataaatt gtcctgtttc caacggttaa
     4861 ggattgcctt gatgtatgca aagtttgctt taccctgact gacagcctct tttaacgcct
     4921 catggataag ctctgggcta aaatcttcta gcatatactg caattcttga atctgtaacg
     4981 gtgacaatgc tttacctgtc tcagcttcaa aagatttata gagatttaca aaatcttgat
     5041 tgatggtaga gggagtgggt gattgttctt tatctacttc tatctctaat tctttctcta
     5101 tctctgttgg acatgagttg gaaaatgtca aagatggttg gacttcttcc aattttcctt
     5161 tttttcgttg ttcacgttta taactcgccc agtttgtttc actcataacc atagcttttg
     5221 cctgtggtag ttctgcgttt ttatcttcgt caatctgtat taaaccgcat tttgtaaagt
     5281 atgccatggt catatctata tcatcttctg atacatctaa ttttagggct aactcttcct
     5341 tgagattgtt aaagtagccc tcatagtata aaatacagtc actttccaag ctctctaaca
     5401 tgagcctaat ataaataact gtcatagtgt acccaccagg taccgtcttt agtctcttga
     5461 taaaaatatt atcaaaaaat ttcttatcaa tttttagcca aaaatagact tttgtttttg
     5521 ccatcgtcct ctcccttgct catttataat tctctacctt gattagtctt aatactcgct
     5581 tgtcattcat tgttagactc attcaattct tccccatacg tctacccctg caagctggat
     5641 atatcgccca taatcagggt ttaaatcctc gctaggtgtt tctatcgtct gttggttttc
     5701 tcgctccagt tgggcgcttt ttttgcggtc tcggtggttt aaataaagca gtaagccaat
     5761 caaaatcacg gtaacaaaaa ccgcctgtgt attgcttata tctagttcat tcatgttatg
     5821 ccctcgcttt gtaattcttg atgtatgcca cttgttcagc tcgcttcata ttcaacaagt
     5881 cgtctatttc cacactggtt acttttttat ttacaaaatc agaaatcagt tgaaaaatgt
     5941 ttggactttg tagctggatt tcagccattg cctcatcaaa ttctgcttgt gtcatgttgt
     6001 ctaaatctag tgtcattgca ttgcctcctc aaacttctct ataagacaac ttttatttgc
     6061 tttctgagtt ccatttttag agttaaaaag aatatatttt aaggttacag tagcctctaa
     6121 atactccttt tcagcatgct ctatatacgc ctgttgctct gcttcgttct caaaaaagtg
     6181 cttagcttag cgtttaaaga atgctttgac taggtttagt ttgaattgcc gtactgcttc
     6241 ggtattcttt agataagtga tcagcaaagt agcctgttgc tcgttcagaa tataggattt
     6301 tttaggttgt cctctagtgt ctaatttatg gattttaaat ccaagtattc ccaactcttc
     6361 aaagtcaacc ttattttctc ttattaagcg tgtgatagtg tggtgttgta cgtcagcaca
     6421 ttcagcgatg atctcgcttg tggtatacgg ctctttcttg ccgtccatgt agactagttc
     6481 cattatggtt ctacctcctg tataaattta gctagcttac tttttaattg tctcctctag
     6541 ccctttttag cctctacaac ggttttggct aacgtgttag aggcttttat aacggcctgt
     6601 atagctgtct ctatttcctc cgtggaatag tagctttgtt ttctaatatc atttaagact
     6661 tgtttaaccc atttcttgaa ataaataaaa ttacatcttc tgtactcttg gcatctgctt
     6721 tatctgagac aaatagaatg tcaatgcctg gtagataaaa cccaccgtct atttgtttag
     6781 ttggtttgaa agtaactatt ttcatttcat aactcctatt ttattgctaa aaataaatac
     6841 acatctgaca gacgatagaa tactttctta gctccatcca tcggggtctg atatcgttta
     6901 agagcaagat cctcccagtt atcaagggtt gtagcactta tacctagcag atccattaat
     6961 tctttacgag aaattaaatc taacttacta gatcgttgtt tttctagctc aactaaagtt
     7021 tcaagagtct gtttaagaag ctgtaaaccc tgtaactgta tttctttaga cagaatttcc
     7081 atttatatcc tccattttcc tttttataaa ttaagttgtc tttttcctct aattttgata
     7141 aaataagaag agattattta gcaaaggggg ttgtcccttt gctaaatacc taacaaaacc
     7201 acgcgccttg cctttgcttg agttttgtta tttttcctta gccgtgtacg ttggtttggt
     7261 cgcctgtaca tggcttttta cttgcgttaa atttattcta ctagccaagt catcacgctc
     7321 tcatagatac gcttagaggc atcatagttt ccattctcaa cttttgttag tgtttgagat
     7381 ttaataccca actgctccga tactgctttt ttggttagct gtaatcttgc acgcttgata
     7441 cgtacttttt cagcaagtga tagtgtaatc aacattggtt tcacctccct tttttctcca
     7501 tttttggcat tttgtgttat aatctcttta gaaaggatgt ataagatgaa tagaattaag
     7561 caattacgaa aagaaaataa tcttactcaa agagaacttg ctaatgagac taaaatccct
     7621 tatagaacca tacaacgttg ggagaatggg gaaactgata taaaatccga tgctgctcag
     7681 gtacttgctg actattttgg agtatcaatt cctcacttac taggttatag cgatttgata
     7741 gcagatacag atagtgatat taaagcaatg gcatactcac atctactaac ttttgtagat
     7801 gaaaaacaaa tcaaagaatt tgaaaaagag ttcattcgtg caaacgataa tagtgatact
     7861 tttggtgatt taggaagtgg tgaaaaggcg ttagaaaaat actatcaagc attatgctat
     7921 ttagttcctc cttttaggga tatattggct aggtatagct ttttgtcact agatgaaaaa
     7981 aaatcagtct ataatattat tgttggttta agtaacaact tatcaaaaga aaataaataa
     8041 ctttaaacat catgtataaa tacctaacaa aaccacgcgc cttgcctgct gatggaaaga
     8101 aaggtacaaa tacatgaata tcatagagaa aattaaaaag aatggccaaa gagtttatta
     8161 tgctagtgtt tatctaggcg ttgaccaact aacgggcaaa aaagcccgta caactgttac
     8221 agcaaccact aaaaagggcg ttaaagtaaa agcgcgtgat gcgatcaata cttttgctgc
     8281 taatggctat acagttaaag ataagccgac aattacaaca tacaatgagc ttgtaaaagt
     8341 ttggtgggat agttacaaga atacagttaa gccaaatact cgccaatcca tggatggatt
     8401 ggttagagtg catttattgc ctgtatttgg cgattacaag ctatctaaac ttactacgcc
     8461 tattcttcaa cagcaagtaa acaaatgggc tgacaaggca aataaaggcg aaaaaggggc
     8521 atttgctaac tactccttgc tccataacat gaataagcgt attttgaaat atggcgtagc
     8581 tatccaggta atacaataca acccagctaa tgatgtcatc gttccacgca aacagcagaa
     8641 agaaaaggct gctgtcaaat acttagacaa caaagaatta aaacagtttc ttgattattt
     8701 agacactctg aatcaatcaa attatgagaa cttatttgat gttgtcctgt ataagacttt
     8761 attggccact ggttgccgta ttagtgaggc tctagctctt gaatggtctg atattgacct
     8821 agaaagcggt gttatcagca tcaataagac actaaaccgc tatcaggaaa taaattcacc
     8881 taaatcaagc gctggttatc gtgatatacc aatagacaaa gccacattac ttttactgaa
     8941 acaatacaaa aaccgtcaac aaattcagtc ttggaaatta ggccgatctg aaacagttgt
     9001 attctctgta tttacggaga aatatgctta tgcttgtaac ttacgcaaac gcctaaataa
     9061 gcattttgat gctgctggag taactaacgt atcatttcat ggtttccgcc atacacatac
     9121 tactatgatg ctctatgctc aggctagccc gaaagatgtt cagtatagat taggccactc
     9181 taatttaatg atcactgaaa atacttactg gcatactaac caagagaatg caaaaaaagc
     9241 cgtctcaaat tatgaaacag ctatcagcaa tttataaaaa ataagggtga cccatttccg
     9301 ggctaccctc ttactatacc aaaaattagt aggggtagta aaaagggtat taaattataa
     9361 aaagcactaa gggaaagcgc cccaaagtgc ttatttcaaa ggctttatag cctataatca
     9421 cataaggaga ttatttttta aggttgtaga atgatttcaa tccacgatat tcagctactt
     9481 caccaagttg gtcttcgata cgaagcaatt ggttgtattt agcgatgcgg tctgtacgtg
     9541 aaagtgaacc agtcttgatt tgtcctgcgt tagttgcaac tgcaatatca gcgattgttg
     9601 aatcttcagt ttcacctgaa cggtgtgata caacagcagt gtaaccagct tctttagcca
     9661 tttcgatagc ttcaaaagtt tcagtaagag taccgatttg gttaactttg ataaggattg
     9721 agttagcagc accttcttgg ataccacgtg caaggtagtc agtgtttgtt acgaagaagt
     9781 cgtcaccaac aagttgtact ttcttaccaa gacgttcagt aagagctttc caaccatccc
     9841 agtcgttttc atccatacca tcttcaatag tgatgattgg gtatttgtta accaattctt
     9901 caaggtagtc gatttgttct gcagatgtac gaacagcagc accttcacct tcaaatttag
     9961 tgtagtcgta aactttacgt tctttatcgt agaattctga tgaagcacag tcaaatccga
    10021 taaatacgtc tttacctggt acatatccag cagcttcaat cgcagcaagg atagtttcaa
    10081 caccatcttc agttccttcg aaacgaggag cgaatccacc ttcgtcacct acggcagttt
    10141 ccaaaccacg tgatttaagg attttcttaa gagcgtggaa gatttcagca ccgtaacgaa
    10201 gggcttcttt aaatgttggc gcaccaactg gcaagatcat gaactcttgg aaagcgattg
    10261 gagcgtcaga gtgagaacca ccgttgatga tgttcatcat tggagttgga agaactttag
    10321 tgttgaatcc accaaggtag ctgtaaagtg ggatttcaag gtagtcagca gcagcacgag
    10381 ctacagcgat agacacaccg aggattgcat tcgcacccaa tttacctttg ttaggagtac
    10441 cgtcaagtgc gatcatagca cggtcaatag cttgttgatc acgtacatcg tagccaatga
    10501 tagcttcagc aatgatgttg tttacgttgt caacagcttt ttgtgtacca agaccaccgt
    10561 aacgagattt gtcaccgtcg cgaagttcaa ctgcttcgtg ttcaccagta gaagctcctg
    10621 atggaaccat accacgtccg aaagcacctg attcagtgta aacttctact tcaagtgttg
    10681 ggttaccgcg tgagtctagg acttcgcgag cgtaaacatc agtaataatt gacatttttt
    10741 actctcctta tgagttaaat tttttacacc tctataatac cttaaaaccc ctcctttttc
    10801 aagaaaaaac gttatctttg tgcaactttt ccttaacttt ataaagtaat cgctttcttt
    10861 tgtctgtttt attctaactt ttatgatata ctgttttcat gacagattta tcaaaacaat
    10921 tacttgaaaa agctcatggt gggttaaaaa taaatccgga tgagcaaaga cgctatcttg
    10981 gtacttttga ggaaagagtt cttggatatg tagatattga cacagcaaat agccctcagt
    11041 tagaaaaagg ctttttattt attttagaaa accttcagga aaaagcagag ccactatttg
    11101 tgaagatttc accaactatc gaatttgata agcaagtttt ctacttaaaa gaagcaaaag
    11161 aaactgatag tcaagccacc atagtatctg aagagcatat tacttctcct tttggcctgg
    11221 ttattcatag caatgcacca gttcaagtag aagaaaaaga ccttcgactt gcttttccaa
    11281 aactttggga agttaaaaag gaagaaccag ccaaaacatc cttatggaag aaatggttta
    11341 gctaaatctt gcacatattt aataagtgcc caatattggc agccgtgcgc tccagataga
    11401 gactggcatt tttcaaacta tcttctaaag gttcactttt ctccaaaata gaaaagacag
    11461 cttggatatt ttcaaatggt aggggaggta aatcttcagc aagactaccg caaatagcaa
    11521 taacaggaac tccaacaggg gttctttttg caacacctat aggcgctttc ccagcaaagc
    11581 tttgactatc aagtcttcct tctccaacaa caaccaagtc agcatctgaa actttcttat
    11641 caaagttgat taagtccaag caggtatcaa ttccagacac gatacttgcc tgagcaaaag
    11701 cacacaaacc accagcaagg cctccacctg ctcctgctcc tttaatttct aatgttgcag
    11761 gtgagaattt ttcataaaaa tcttggatcg cctgatctac gactgcaaac atagtcggat
    11821 gtcgaccttt ttgattgcca aaagtataag tcgcaccttg atgaccacat aagggactta
    11881 cgacatctgc taaaatatga atttgaacac cttcaggaat tttatagcaa ttttctgttg
    11941 aaacagaagc taagtttaat aaggattgac cggaagcagg caagacattt ccatccctat
    12001 cataaaattg ataacctaaa ccagcagcaa tccccagtcc tccatcatta ctggccgtgc
    12061 caccaacatc gatataaata tctttaatcc ctttagaaat gagatggaga atcaactctc
    12121 caataccaca agtttggatt tgaagtggat ttcgtttctc tagcggaatt tttccaagac
    12181 caaccaagtc agctacttca aatagtgcca gttccccttt ttgaaaatag cgcatggctt
    12241 ctttttgtcc aaaagggtct gtcacttgga tccatttttc ttttaggtca agagaatgtc
    12301 ggatagcatc tacagtacct tctcccccat caccaacagg gcagaggaga cattctacat
    12361 ctgctatcga ttgttggaag cctcttttta ttgcttcagc tacctgttga gctgtcaagc
    12421 tttccttaaa cgaatccggt gcaattacaa tcttcatatt ttccctcatt ctaaacagtc
    12481 aatcaaagga agaacttcta aaaaatccct cttgtcaaca tgatgtggta tttctttttt
    12541 gagcatttct ttggaacaaa aggcgattcc taactccgcc gacttcaaca ttaatagatt
    12601 attgccccca tcaccgattg ccaccgttct ttctttagaa agttttagtt tctttctcca
    12661 tttttccaga gtttcttttt tgacctgggg acttataatt tgtccaacta attttcctgt
    12721 taaaagacct tctttgactt caagctggtt agcagtgaaa taggcaatac caagggattt
    12781 tgctaatctc tccaactatt ggtgtaaatc caccagacac cagaccaact aggataccat
    12841 tcttttggag aatagagatg aactctggga catttagcga tagatgaatt gagttgaaga
    12901 cgttatcaaa gaccaaaata ggaagacctt ccaacaagga cactcttttt cttaaactgc
    12961 tttcaaagac caactctcct cgcattgctc gacttgtaat ctgcgaaatt tctgcctcat
    13021 gacctgcctc tctccctaaa agatcaatca cttcttctag gattaaggtt ccatctacat
    13081 ccaaaacaca caagcctttt acttgagaca tcagttctcc tctctaaaca gcctaaaaat
    13141 cgtatgaagt catcatacga ttttatctat taattaacta aactatggta caagtcaagg
    13201 tatgacttgc aggctgtatc ccatgagaag tcactctcca tagcttgttt ttgtaggttt
    13261 ctccaaatgt ctggatggtt tctatacaag tccaatgctg tttggaaagt ccaatttaac
    13321 caataaggag atagattgtc aaagctaaag ccagtaccgc ttccttcgat tggattgaaa
    13381 gcgcgaactg tatctcgcaa gcctccaact tcatggacca atggcaaggt tccataacgc
    13441 atagccatca tttgagacaa gccacacggt tcaaaacgac ttggcatgag gaagaggtca
    13501 caagcagcgt agatttcctg agcaagtttg acatcaaaag tgatatttgt tgatagcttg
    13561 tctgggtaaa tctgagcaaa ccatgagaaa gctccttcaa aggctggatc gccagttccc
    13621 aaaagaacaa tctgaacatc ttcttgcaag atatggtgaa gactttcgac caccacatca
    13681 aaaccttttt gacgtgtcaa acgagaaaca attcccacca gtggaacgtc tgctctaaca
    13741 ggcaagccaa ctctttcttg caattttgcc ttatttttgg ctttcccaga caaatcttcc
    13801 tgattgaaat gatagtctaa aagagcatcc gtctgaggat tataaagatc agcatcaatc
    13861 ccattcacga taccagatac tttaccagac tccattttaa gaatctgatc caaattacat
    13921 ccaaactgac tagtcataat ttcatgagca tagctaggtg aaacggttga aacacggttc
    13981 gcatagagaa tacctgcctt catccagttc agacagttgt tccatcgaag ggtgccatca
    14041 gcgtaacgtt caaagccaac tccaaacaaa tcacccaaca ttccttctga aaattgtcct
    14101 tggaattcta aattatgaat ggttaaaact gtttcaatgt cctcataggc ttgaatccaa
    14161 cggtattttt ccttcaacaa gaaaggaatc atagctgtat ggtagtcatg aacatggaga
    14221 agatcaggaa taaagtcaat cctttccata gcctcaatgg cagccagttg gaaaaaggca
    14281 aagcgttctc cgtcatcaaa atcaccgtaa acatgaccac ggaagaaata atattgattg
    14341 tcaataaagt agaaggttac accatttaat actgttttct taattccaca atactgtctg
    14401 cgccaaccaa cgctcacctc aaaatgaagc acatcttcaa tctgatttcc aaatttagcc
    14461 tctaccatat catagtaggg taaaatcact gcaacttcgt gcccagcttt taccagtgat
    14521 tttggaagag cgccaatgac gtctcccaaa ccacctgttt ttgaaaaggg tgcaccctct
    14581 gctgctacaa ataaaatttt catgaatgaa tatcctctgt tactttagca cctttcttaa
    14641 ccacaactgg atgttctgca gttcctcgaa tcacaacacc aggctcaact tcaacccctt
    14701 tgtccaagat agcatattcg acctgagccc cttctccaat aacaacacga gggaagagca
    14761 ggctatcttt aaccaagcta tccttatgga catggatatt acgtgataga acagaattag
    14821 ctacttgacc ttcaataata ctaccagagg caaactgaga agttcttacc ttagatgtat
    14881 tagcatagta agttggctct tcgtttttga cctttgtata aatcttttgg tttggtgaga
    14941 aaagagaata gaatttttgt gattcaagca tatcgatatt cgcttgataa taagatttaa
    15001 cagagtgaat attggctaga tagcccgtgt actcgtaggc gaaagctccc tcttttacag
    15061 ccaaatcccg taaaacatag cgcaatttct ctggatgttc ttttttagct tcttcttcca
    15121 agtgttcaat caaccaaggt gtatcaacga caaagatatc tgtagacata ttgaacgttt
    15181 cagctgttga cttgctatca aagagtttat gagaaagaac atggtctgtt tcatctacat
    15241 ccaagattgc atttacttct gaaatatctt tcttagctag ttttttataa actacagtga
    15301 taggctcttt tgttgtacta tgtaggtgga aaacttggtt caaatcaatg ttaataagaa
    15361 catcgcagtt gagggcaacc gtttggtttg agccagaacg tttcaaataa gtaagaagct
    15421 gttggtagta ttcttttcca actgtactac tttctacacg ggtattgtaa attcctagat
    15481 agtaatggct aagaaaggtt gataagcccc actcgcgtcc tgaacgaata tggtcaaata
    15541 ctgagctgat attatcctgc tggaaaatac caaagacact acgaacacct gcattagcaa
    15601 ggcttgaaag tgggaagtca atcaaacgat atttcccacc aaatggcaaa cttgctactg
    15661 gacggtggtc cgtcaatgtc gacatattgt gaaaaccaac tgtatttcct aaaatggcag
    15721 aatatttatc aatcttcatc tgttgctacc cccactactt cattatatcc tacaacttgt
    15781 acttcatctg ttccatcaat ttcgacaccg tcagaaataa tcgcaccttc accaataatg
    15841 gcacgtttaa tcttagctcc ttgaccaatg atagctccac tcatgataac tgaatcaagg
    15901 acttccgctc cttcgcgaac ttgcgcgcct gttgaaagga tagaatgttt aacagttcca
    15961 tcaacgaaac atccgtctac aactaatgag tcttccacat gagcatttgc cccgaggaag
    16021 tttggtggtg aaatcaagtt tcttgagtaa atcttccatt gacggttacg actatccaag
    16081 gcattttctg gagaaatata ctccatgttc gcttcccaaa gtgactcaat agtaccaaca
    16141 tctttccaat aaccactaaa ttcgtaagca taaacacttt cacctgactc aaggtaattt
    16201 ggaatgacat ttttaccaaa gtctgacatg ccaaccttgc tcttttcagc agcgactaac
    16261 atattacgaa ggcgttgcca atcaaaaatg tagattccca tagaagcttt tgtagattta
    16321 ggttgagctg gtttttcttc aaattcaaca atacgattgt tagcatctgt gttcatgata
    16381 ccaaaacggc ttgcttcttt aagagggacg tctaaaactg ctactgtcaa gctggcatta
    16441 ttatccttat gagactggag catatcatca tagtccattt tgtagatgtg atccccagac
    16501 aaaatcaaga catactcagg attgacactg tcgatatagt cgatattttg gtaaatagcg
    16561 tgactagtcc cctcaaacca acgatttcct tcacttgcag aataaggttg aagaatagag
    16621 acacctgaat taataccgtc tagtccccag cttgaaccat tcccaatatg gttgttgaga
    16681 gcaagtggtt gatactgtgt aacgacccca acattatgaa tccctgagtt ggcacagttt
    16741 gatagggcaa agtcaatgat acggtagcgc ccaccaaatt gcacagctgg ttttgcgatg
    16801 ctttgagtga gtttaccgag acgagttcct tgcccaccag caagaatcaa agctaacatt
    16861 tcatttttca ttttctactc ctttttggtt tttatttgtg acggttttag tagatttcaa
    16921 gcgacgtttg attttccata cacttgctcc catagccggt agggtaaagg ttaaggtctg
    16981 ctcataatct ttccatagtc cttcttgcgt ttgaacagtt tgattatgtt ctttccaaac
    17041 gcctccccac tcttccaact cagtattcca tacttcttcg taaattcctg caacgggtag
    17101 tccgattgta aaatctttcc gctcaacagg taccatgtta aagatacaga ctaacatttc
    17161 tcccttttta cccttacgaa taaaggaaag aacactctgg tctcgattat ccgcatcaat
    17221 gacttcaata ccatcatagc tggtatcgat ttcccacaga cagcgatgat ctttgtaaaa
    17281 ctggtttagc tgagaagtga aatacttcat cttagcattc attgggtctt ctaggttaga
    17341 ccattccaac tgttcttcag atttccattc taggaattga ccgtattcgc tacccatgaa
    17401 gagcaatttc ttaccagggt gacaaatttg gtacgtatag agattgcgca agcctgcgaa
    17461 ttgattgtaa cgatctcccc acatcttatg catcatactc ttcttgccat gaaccacttc
    17521 atcgtgcgag aatggcaaga gataattctc cttgaaaaca tacataaagc tgaaagtcac
    17581 caggttaaag tcatatttac gataaatcgg atcttcttcg tagaaacgga ggatatcatt
    17641 catccagccc atgttccatt tgtagtcaaa tcctagacca ccaatctctt tcattcccgt
    17701 aatcttggtt gcagacgaac tttcttctgc aatcatcatc acatctggat attctaactt
    17761 aataacttca ttcaagcgtt gaaggaaata ataaccttca tagttgagat ttccgccatc
    17821 tttattaggt gtccatggag catcatcata gtccaaatag agcatgttgc taacagcatc
    17881 cacacgaata ccatccaaat gatagatatc aatccaatgc ttaatgcaag aaattaagaa
    17941 ggactggact tcattttttc caaggtcaaa attaagggca ccccaaccat ggttatgagc
    18001 cttattatgg tcttggtatt caaaagtcgg tgtcccatca taataggcta aggcatcatc
    18061 attgatggta aagtgacctg gtacccagtc cacaataacc ccaatattat gggtatgaca
    18121 ctcctcgaca aaatcttgaa actcctctgg tctaccatag gcatgctcta aagcgaagta
    18181 acccataagc tggtaccccc aactcaaacc tagtgggtgg gacatcaagg gcataaactc
    18241 aatatgagta tagttcatct caactaggta aggaatgagt tcatctttca attgggcaaa
    18301 actataagga ctgccatcag gatttctctt ccaagagcca gcatgaacct cgtaaatatt
    18361 gacaggacgt tcagcaaagc cccaacgttt tcttcgtgcc agccaaagtc catccctcca
    18421 tttcttatca ggaagctctg ttacgattgc ccctgttcct ggacgagcct catacctgac
    18481 agcaaaaggg tcaatcttca tcagttgatg accattttga cgtgtgacat gatatttgta
    18541 aatatgccct tcttgagcca tattggtaaa gacttcccag accccaaagt catttcttac
    18601 cattggaatc tgattttcaa tccaattggt aaaatcacca accaagtgaa cagcctgagc
    18661 attaggtgcc caaacacgga aggtatagcc atactctcca tttagttctt ccctatgtgc
    18721 tcctagataa tgttggagat aaaaattttc acccgtcata aaggttttta atgcttctct
    18781 attatccata tactcccttt ctcctgtaag cgttttctat gtttttatta tactaccttt
    18841 ttagagaaga ttcaagtaaa ttactatact tctttaatta ttttgaaaat ctacaacaag
    18901 ttcacttact cgttcaattg taaatcaata ttttttcaaa aaattgcgaa aacacctttc
    18961 tttttctact atagtgaaat gaaataaaac atgcgcaaat cgattaagga atttaatcta
    19021 atttctaaca atgtcttaga aatcaa
//
LOCUS       DAVAZT010000045        17780 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVAZT010000045 DAVAZT010000000
VERSION     DAVAZT010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17780)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17780)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17780
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.045"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..136)
                     /locus_tag="VQT45_001535"
     CDS             complement(<1..136)
                     /locus_tag="VQT45_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET2359837.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     D"
     gene            complement(387..1322)
                     /locus_tag="VQT45_001536"
     CDS             complement(387..1322)
                     /locus_tag="VQT45_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HET2359838.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1319..2179)
                     /locus_tag="VQT45_001537"
     CDS             complement(1319..2179)
                     /locus_tag="VQT45_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HET2359839.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFYYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2287..4449
                     /locus_tag="VQT45_001538"
     CDS             2287..4449
                     /locus_tag="VQT45_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HET2359840.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATITSYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIATLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIILSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYFYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4541..5800
                     /locus_tag="VQT45_001539"
     CDS             4541..5800
                     /locus_tag="VQT45_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2359841.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADDTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRSE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5814..6680
                     /locus_tag="VQT45_001540"
     CDS             5814..6680
                     /locus_tag="VQT45_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2359842.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6694..7527
                     /locus_tag="VQT45_001541"
     CDS             6694..7527
                     /locus_tag="VQT45_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2359843.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKSTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIIAGISNGAV
                     K"
     gene            7528..7608
                     /locus_tag="VQT45_001542"
                     /pseudo
     CDS             7528..7608
                     /locus_tag="VQT45_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            7746..9188
                     /gene="gtfA"
                     /locus_tag="VQT45_001543"
     CDS             7746..9188
                     /gene="gtfA"
                     /locus_tag="VQT45_001543"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HET2359844.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTEILPEIHEHYSIQFKIADHDYYVYDFTLPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAREVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVSF"
     gene            9326..10519
                     /locus_tag="VQT45_001544"
     CDS             9326..10519
                     /locus_tag="VQT45_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HET2359845.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11206..13185
                     /locus_tag="VQT45_001545"
     CDS             11206..13185
                     /locus_tag="VQT45_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2359846.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13252..14748
                     /locus_tag="VQT45_001546"
     CDS             13252..14748
                     /locus_tag="VQT45_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2359847.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14748..15674
                     /locus_tag="VQT45_001547"
     CDS             14748..15674
                     /locus_tag="VQT45_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2359848.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSIRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15683..16750
                     /locus_tag="VQT45_001548"
     CDS             15683..16750
                     /locus_tag="VQT45_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2359849.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16761..17687
                     /locus_tag="VQT45_001549"
     CDS             16761..17687
                     /locus_tag="VQT45_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2359850.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
BASE COUNT         5230 a         3169 c         3713 g         5668 t
ORIGIN      
        1 aatcagggca agatggagcc tcataatcca gcttagcgat aatttctttg tgggtatcca
       61 tattgatgat atctagaatc ttgatgtttg ggtctttaat gtctagtaat tttgtgataa
      121 aatgtaattg ttccatatga ttctttctaa tgagttgttt tgtcgctttt cattataggt
      181 catatgggac tttttttcta cacaaaatag gctccataat atccataggg aatttaccca
      241 ctacaaatat tatagagccc gttttaatga gagtttgtaa ctctcttttt tgtttttaga
      301 gacaataaaa cttcagatcc gtaaaactta attgaattac taatctgaag ttatttttat
      361 atcgtttata ttataattgt gttattttac ttccaactat tgagagaaat ttcgccacta
      421 tttagccaga tttcttttcc gttatcacat tgaactaaaa gttttccatt ttctgagatg
      481 tctttagcaa gtcccttgta gtctttttgc tctagtgtga aagtgacttc ttttcctaga
      541 atgaatgact gttttttgta taggtataat agctcttctg ctggtgtttc gaagaaagca
      601 cgccagattt ctatgatcaa ttcattcctt gttataggag ctgtagcttt aaataagctg
      661 gcagcttttt cttttaattc ctgagggaag tctttaatag tgaaattgat acctactcca
      721 ataatgatat ctgtgactaa gccagtttct acagaggtca ttgcttcagt aaggattcct
      781 ccaattttat gattgtttag atagatatca ttgacccatt ttatgtcgac atctattaaa
      841 gttaggttct taatggcttt gtagacagct ccagctacaa gtagtgtgta ggatggtaat
      901 ttgtcatagg ggagatttgg tttaagatgg agtgtcatat aaataccacc ttgtggtgag
      961 tagaaggaac gttgaaaacg gcctcggcct gctgtttgat aggaagctag atagagggta
     1021 tttgcttcat ggcctaaatc aattgcttct tttgcatcta gttgtgttga ttttgtttcg
     1081 ggtttaaagc tgactttaat tggaagattt tcttctagaa tctctggaag aataaggtca
     1141 ccattcatca gtttatatcc tctatttttg atactatcaa tttcaatgcc ttcttgttct
     1201 agtcgcttga tggctttcca aattgctgtt cggcttaggg atagtttttc tgcgattttt
     1261 tctccgctga tatagtcggt ttctttagat aggatttggt agacagcttg gtaggatttc
     1321 ataatgttgc ctttctcact agttggtatt gagagtattc ttttcttgta tgacttggag
     1381 tctgattaaa gtattgttta taagctttcg aaaaatggag tggatctgaa aaacctaccg
     1441 agtatgcaat taccttgatg gactcttggg tattttcgag aagttgtcta gctcggtgca
     1501 ttcgaacgta gagtaggtat tctttgggtg ataaggtatt aaattctttg aatacgcttg
     1561 ataagtagct tctgtgaacg gatagttctt ttgctaaatc ttgaattgta agtgattgag
     1621 gatagtggct atcaattaat cgtttgcatt caagatagag ttggtgggtt gatgaaatat
     1681 tctttttttt ctgattggga gcaatagttc ccagatgaaa catcagttca tgaagttgtc
     1741 ccatgatatg gagttgagct aattcacttg attttgtaat ctgagcgaag cggacaatgt
     1801 ctgagatgag ttttgcagta gtctgggtat gacaagtttc agattggatg agataggatt
     1861 gatcagaaat ttgagaaaga gcaaaataat caggggattt ccctccagtg attcctaacc
     1921 agtagtaggc ccaaggttct ttactatctg cttgataaaa ggttagttcc tctggtttta
     1981 atagaaagaa atctccttct tttaaatcaa caattttacc cttgtaataa aattttcctt
     2041 gtcctttagt aatgtaatgt agaacgtatg tatcacgaat ggctggacca aaagagtaat
     2101 taggtgtgca ttcctcatat ccataaaagc ttagggcaag gtcgattgtt ccagtctggt
     2161 attctgaaaa aactaacatg tgctacctcc tacctaacat tttaccatat tcttgagaca
     2221 tttttctatt ttggaaagcg atttcaggtg ataaaatata atcaataaag tgatgaggtg
     2281 aagtaaatgg gagttaggat agagaataat ctattttatg ttgagagtaa aaatctaagt
     2341 ttgattattg aaaatcgaaa tggctactta cttttgaaac atttaggaaa gactattaag
     2401 aactataaag gttccaatag tgtttatgaa cgagaccatg ccttttcagg aaatccaacg
     2461 gctactaatc gaacctttag tttagatact cagcgacaga tttttggaca acatggctta
     2521 ggagatttta ggaaaccaac tatacaggtt cagcatagtg taactgaagt aacagacttt
     2581 cgatttgtag aagcaaagat tttaaaaggt cagaatggtc cacagggctt accttctcca
     2641 catagcatgg acgatacaga gactcttgtc ttaatgttag aagattctaa ggctcaactt
     2701 agtctgactt tgtattatac tacttttaat aatgatgcga ctattactag ctacagtaaa
     2761 ttagataata atagtaatca ggaagttgtc atccataaag atttttcttt tatggctgat
     2821 tttccagctg cagattacga aatagcaact ctgcagggtg cttatgctcg tgaaaagact
     2881 gttagacgtc aacaggtaga acaaggaatc ttttcgatta gttcaaaccg aggtgcttct
     2941 ggtcatgctc aaacaccagc tcttctacta tgcgaacaag gagtcacaga ggatgctggg
     3001 aatgtgtttg ctattcaact aatgtatagt ggcaactttg aagcttttgt tcaaaaaaat
     3061 caattgaatg aagttcgggt ggctattggc attaatccag aaaacttttc ttggaagtta
     3121 gcccctgagg aatactttga aacaccggta gctttagtga ctcattcaga tcagggatta
     3181 actggtatta gtcatgaaag tcagaatttt gtactgaagc acattattct aagtgaattt
     3241 tctaaaaaag aacgtccaat tctaatcaat aactgggaag ctacttactt tgactttcag
     3301 agagaaaaac tgttagagtt agcagatgaa gctaagaaag ttggcattga actttttgta
     3361 ttagatgatg gttggtttgg caatcgtttt gatgataatc gtgctttagg tgattgggtt
     3421 gttaatgagg aaaaactggg tggaagtcta gaaagtctga tttcagctat ccatgaaaga
     3481 ggtttgcagt ttggactttg gttagaaccc gaaatgattt ctgtagatag tgatttgtat
     3541 cgtcaacacc ctgactgggc tattcaggtt cctgactatg agcatactta ttctcggaat
     3601 caattagtac ttaatcttgc caatcctcag gtagtagaat acttgaaaag tgtcttagat
     3661 caactcctat cttatcatga gattgattac attaaatggg atatgaaccg caatatcact
     3721 aagctaggga atggattaac ttatctagag acacagatgc aatctcatca gtacatgctg
     3781 gggctttatg aactcgtttc ttatctgaca gagaagcaca gccatattct ctttgagtcc
     3841 tgctctggtg gtggtggacg aaatgatctt ggtatgatac gctatttccc acaagtctgg
     3901 gctagtgata atactgatgc cattgcacgt ttaccaattc aatacggttc atcctatttc
     3961 tatccaacca tttctatggg ggctcatgtg tcagcagtac cgaatcatca gatgggacga
     4021 atgacaccat tagaaacacg tggccatgta gcaatgatgg gaaatttggg ctatgagctt
     4081 gatttgacaa atttatcaga tgaagagaaa gctacgattg ctaatcaggt gaacttgtat
     4141 aaagaattac gaccagtagt tcagttagga cagcagtata gactaattaa tcctgatact
     4201 gcatccaatg aagcagctgt acaatttaat tacggaaatc aaacgattgt aacctacgtt
     4261 cgcgttttat ctgttgtaga gaccatggaa acaactttaa aattaaaaga tttggatgaa
     4321 gagggactat ataaattaca ggaaaatggc gaagtttact caggtgcaga actaatgtat
     4381 gcgggcttaa ctgttatctt atcccaagga gattttttga gtagacagta tatttttaga
     4441 aaactatgat atgtactgac cccaaaagtt agatttattc tatctaactt ttgaagtgca
     4501 gtttgataag ggtgtataaa tttataaagg aggctttcta atggaatggt ataaaaaaat
     4561 cggacttctt gcaactacag gtttagcttt gtttgggctc ggtgcttgct ccaactatgg
     4621 taaatctgcg gatgacacag tgaccatcga gtatttcaac cagaaaaaag aaatgaccaa
     4681 aaccttggaa gaaatcactc gtgattttga gaaggaaaac cctaagataa aggtcaaagt
     4741 cgtcaatgta ccaaatgctg gtgaagtatt gaagacacgc gttctcgcag gagatgtgcc
     4801 tgatgtggtc aatatttacc cacagtccat cgaactgcaa gaatgggcaa aagcaggtgt
     4861 ctttgaagat ttgagtaaca aagactacct gaaacgcgtg aaaaatggct acgctgaaaa
     4921 atatgctgta aacgaaaaag tttacaacgt tccttttaca gctaatgctt atggaattta
     4981 ctacaacaaa gataaattcg aagaactggg cttgaaggtt cctgaaacct gggatgaatt
     5041 tgaacagtta gtcaaagata tcgttgctaa aggacaaaca ccatttggaa ttgcaggtgc
     5101 agatgcttgg acactcaatg gttacaatca attagccttt gcgacagcaa caggtggagg
     5161 aaaagaagca aatcaatacc ttcgttattc tcaaccaaat gctattaaat tgtcggatcc
     5221 gattatgaaa gatgatatca aggtcatgga catccttcgc attaatggct ctaagcaaaa
     5281 gaactgggaa ggtgctggct ataccgatgt tatcggagcc ttcgcacgtg gggatgtcct
     5341 catgacacca aatgggtctt gggcgatcac agcgattaat gaacaaaaac cgaactttaa
     5401 gattggaacc ttcatgattc caggaaaaga aaaaggacaa agcttaaccg ttggtgcggg
     5461 agacttggca tggtctatct cagccaccac caaacatcca aaagaagcca atgcctttgt
     5521 ggaatatatg acccgttcag aagtcatgca aaaatactac gatgtggacg gatctccaac
     5581 agcgatcgaa ggggtcaaac aagcaggaga agattcaccg cttgctggta tgaccgaata
     5641 tgcctttacg gatcgtcact tggtctggtt gcaacaatac tggaccagtg aagcagactt
     5701 ccataccttg accatgaact atgtcttgac cggtgataaa caaggcatgg tcaatgattt
     5761 gaatgccttc tttaacccga tgaaagcgga tgtggattag gagtagagag actatgaaaa
     5821 aagtattaca aaaatattgg gcatgggctt ttgtggtcat ccccctcttg ttacaagcaa
     5881 ttttcttcta tgtgccgatg tttcaaggag ccttttacag ttttaccaac tggacaggat
     5941 tgacttacaa ctacaaattt gtcggcttaa acaactttaa gctcctcttc atggatccaa
     6001 aattcatgaa tgcgattggc tttaccgcaa tcattacgat tgccatggtg gttggtgaga
     6061 ttgcactcgg gatcttcatt gcgcgtgtct tgaactctaa aatcaaaggc caaaccttct
     6121 tccgtgcttg gttcttcttc ccagctgttt tatctggttt gacagtggct ttgatcttca
     6181 agcaagtctt caactacggt cttccagcga ttgggaatgc ccttcatatt gaatttctcc
     6241 aaaccagtct tttagggact aagtggggag caatctttgc ggctgtcttt gtccttcttt
     6301 ggcaaggggt ggctatgccc atcatcatct tcctagctgg tttgcaatct attccaactg
     6361 agattacaga ggcagcaagg attgatggtg cgactagcaa gcaagttttc tggaacattg
     6421 aattgcctta cttgctacca agtgtctcta tagtctttat cctagcccta aaaggtgggc
     6481 tgactgcctt tgaccaagtc tttgccatga ccggtggtgg tccaaacaat gccacaacct
     6541 cacttgggct cttggtttat aactatgcct ttaaaaacaa ccaattcggt tatgccaatg
     6601 ccattgccgt aatcttgttc ttcttaattg tagtgatttc gatcatccaa ttgagagtat
     6661 ctaagaaatt tgaaatttaa gaggagaagc atgatgaaac aagatgaaag aaaagccctg
     6721 attggcaaat acattctatt gattctagga tcggttctga ttttagtgcc gctccttgct
     6781 accctcttta gttccttcaa atccactaag gatattgtag ataatttctt tggctttcca
     6841 accaacttca catgggacaa ctttagccgt ctcttagctg atgggattgg aggctattat
     6901 tggaactctg tcgtcatcac tgtcttgtct ttacttgcag taatgatctt tatccctatg
     6961 gcagcctact ccatcgctcg caatatgagt aaaagaaaag cctttaccat catgtatacc
     7021 ctcttaatcc tcggaatctt cgtacctttc caagtcatca tgattccgat tacggttatg
     7081 atgagtaaac tcggtttggc taataccttt ggtttgatct tgctctactt gacctatgcg
     7141 attccacaga ccctctttct ctatgttggc tatatcaaaa tctcgattcc agaaagtctg
     7201 gatgaagcag cagagatcga tggggctaat caatttacaa cctatttccg catcatcttc
     7261 ccaatgatga aaccgatgca tgcgacaacc atgatcatca atgccctttg gttctggaat
     7321 gacttcatgt tgccactcct tgtcttgaac cgggattcca aaatgtggac tctgcctttg
     7381 ttccaataca actacgcagg ccaatatttc aacgactacg gaccaagctt tgcctcttac
     7441 gtggtcggca ttatcagtat caccattgtc tatctcttct tccaacgcca tatcatcgca
     7501 ggaataagca acggggcagt gaagtaatac tcaatgaaaa tcaaagagca aactaggaag
     7561 ctagccgcag gttgctcaaa acactgtttt gaggttgtgg atgaaactga cgaagtcagt
     7621 aaccatatct acggtaaggc gacactgacg tggtttgaag agattttcga agagtataac
     7681 atgaatttga tttacgaagc cagatcatat gagacttggc ttcaattaga aaaaggagag
     7741 taatgatgcc aattcaaaat aaaaccatgt tgattaccta ttctgatagc cttggaaata
     7801 atcttaaaga cttatatgat aatttggaag agcattttgg agatgctatt ggaggagttc
     7861 accttttacc atttttccca tcaacaggtg atcgtggatt tgcgccagtt gactacgacg
     7921 aagtggactc agcttttggt gattgggagg atgttaagcg tttaggtgag aaatattatc
     7981 ttatgtttga ttttatgatt aatcatattt ctcgtcaatc caagtattat aaggactatc
     8041 aagaaaaaca tgaagccagt gaatttaaag atctcttttt aaactgggat aagttttggc
     8101 cagaaaaccg tccgacacag tctgatgtag atttaattta caagcgtaag gatcgtgcac
     8161 caaagcaaga gattgtgttt gaagatggtt cagtggaaca tttgtggaat acctttggtg
     8221 aggagcagat tgatcttgat gtgaccaaag aagtaactat ggaatttatc cgtaagacca
     8281 ttcagcactt ggcaagtaat gggtgtgatt tgattcgtct agatgccttt gcttatgcag
     8341 tgaagaaatt ggatactaat gatttctttg tggaaccaga tatttgggat ttattggaca
     8401 aagttcgaga tatcgctgct gagtatggga cagagatttt acctgagatt catgaacact
     8461 attcgattca gtttaaaata gcagaccatg attactatgt ttatgatttt actcttccaa
     8521 tggtgacact ttatactctt tacagttcca gaacagagcg tttggctaag tggttgaaga
     8581 tgagcccgat gaagcaattt acgacgctag atacccatga tgggattgga gtagtagatg
     8641 tcaaggatat cctgaccgat gaggagattg actatgcttc aaatgaactc tataaggttg
     8701 gagccaatgt caaacgtaag tactctagtg ccgagtataa caacttagat atctaccaaa
     8761 tcaattcaac ctactattca gcgcttggag atgatgatgt caagtatttt ctcgctcgtc
     8821 taattcaagc ttttgcccca ggtattcctc aggtttacta tgtgggtcta ttagcaggca
     8881 agaatgactt gaaattatta gaagaaacta aagaaggtcg aaatattaat cgtcattact
     8941 atagcaacga ggaaatagca agagaagtgc aacgacctgt tgtgaaggcc cttctcaatc
     9001 tattttcttt ccgtaaccgt tcagaagcct ttgatctaga agggactact gagatagaga
     9061 caccaacagc tcacagcatt gtaatcaaac gtcaaaataa agataagtcc gtaacagcag
     9121 tagcagaaat tgatttgcaa aatcagactt atcgggtaat tgagaatgga gttgaagtat
     9181 cattttgaag ccttgatatg gtggataaaa tagggttttt attttggaaa acgtttcctt
     9241 tgttttcaaa ttgctaaaaa agtggtacaa tataggatag cttactatta tctgaatcag
     9301 ctgatttgga gagaaaggat tcattttgaa atcaataggc tttattgaaa agctgaaggg
     9361 gttgtctagt aaagagctga ttttattggg aattatccta agtatctttt taccctttta
     9421 tctttttgta gttgtactct gtttatatat tatcagtttg atttttacag gagacatgaa
     9481 aagtattctt cagaaaatgg gggagcatcc gatgctgctt ctttttctta gctatagtac
     9541 tgttatatcc attcttgcac aaaattggat gggtcttgtg gcttcagtag gaatgtttct
     9601 atttactatt ttctttttgc actatcagtc gattttatcc cataaattct ttcgattgat
     9661 tttgcagttc gtcttgtttg gtagtgtctt gtcagctgct tttgccagtt tagaacattt
     9721 ccaaattgtg aagaaattta actatgcttt tctttcaccc aatatgcagg tgtggcatca
     9781 gaaccgggca gaagtgacct tctttaatcc taattattat ggaattattt gttgtttctg
     9841 tattatgatt gctttctatc tgtttacaac gaccaagttg aattggttga aagtattctg
     9901 tgtgattgca ggctttgtta atctctttgg tttgaacttt actcaaaatc gaactgcctt
     9961 tcctgctatt atcgctggag caattatcta tctctttacg actattaaaa actggaaggc
    10021 cttttggctt agtattgggg tcttcgcgat tggtttgagt ttcctctttt ctagtgattt
    10081 gggagttcga atgggtactt tagactcttc tatggaagaa cgcatttcta tctgggatgc
    10141 tgggatggcc ttgtttaagc aaaatccttt ttggggtgaa gggccattga cctatatgca
    10201 ctcttatcct cggatacatg ctccttatca tgaacatgcc cacagtcttt atattgatac
    10261 gattctgagt tacggaattg tgggtaccat tttattagtt ttgtcttctg ttgctcctgt
    10321 tcgcttgatg atggatatga gtcaggagtc ggggaaacgt ccgattatcg gcctttatct
    10381 atctttcctt acagtggttg ctgtgcacgg aatttttgac ttggctctct tctggattca
    10441 gtcaggcttt attttcttgc tagttatgtg cagtattcca ttggagcatc gaatgttggt
    10501 atcggacatg acggattaag ttttataagt ttgaaatctt ctaccttggg taggagattt
    10561 ttttatacga tgggcatgtc gtgcatctga ggtgtaagtc ctctgtaggg atccactacc
    10621 ggtgaataca atagcgctcc ccaagcctga ctatcgtgag gtagcggatt aaaatggtct
    10681 ggggatagat cgttttaagt ctgacgcagg aaataagaat tgtcagagaa agcaatagtg
    10741 aaatcgtagg ctatgaatag aaacgtgata gcgaggagca tatagtggat aaggtagcga
    10801 gaaattttaa agtataaaag atagtcttaa tctatatatg taaatcacaa aagtaattga
    10861 attcggaata aggttggtgt gaaaagacat agtaaactga atcttgaata ctagaatgat
    10921 acttctacaa tattgttata atttaatttg aattccaaaa tcacattgtt ccgtccgtat
    10981 ttcattttac tgtatgtctt cctaaactcc aaagtttctg cgtcaaattt cctattttca
    11041 ctgtagtctt tgacacttcg aacgacaatt tgaatcatat attcaaaaaa aaatgaaaaa
    11101 tttgtgccaa caagcctaaa tattctgaaa atttgtttga tttttaatgg ataatgtgat
    11161 ataatggttg tcaatctata attcacataa acagaggagt agaaaatgaa aaaaaatcgt
    11221 gtatttgcta cagcaggtct tgttttatta gcagcaggtg tacttgcagc atgcagttct
    11281 tcaaaatcat ctgattcatc agcccctaaa gcttatggct atgtttatac agcagaccca
    11341 gaaaccttgg actacctgat ttcaagtaaa aatagtacaa cagtagtgac ttcaaatggg
    11401 attgatggtt tattcactaa cgataattac ggtaatcttg ctcctgcagt tgcagaggat
    11461 tgggaagtct ctaaggatgg tttgacctac acttataaga ttcgtaaagg ggttaaatgg
    11521 tttacctctg atggagaaga atatgcagag gtgacggcta aagatttcgt gaacggttta
    11581 aaacacgcag cagataaaaa atcagaagct atgtatttag ctgaaaattc ggttaaaggc
    11641 ttggcagatt atctatcagg aacttcaaca gatttttcaa cagttggtgt caaggcggtt
    11701 gatgattata cgttacaata cactttgaac cagcctgaac cgttctggaa ctctaagttg
    11761 acctattcta ttttctggcc tctgaatgaa gaattcgaaa catcaaaagg aagcgatttt
    11821 gctaaaccaa cagatccgac atccttgctt tataatggtc cattcttgtt gaaagggttg
    11881 actgcaaaat cttctgtaga gtttgtaaaa aatgagcaat attgggataa agaaaatgtc
    11941 cacctagata ctatcaatct agcttactat gatggatcag atcaggagtc gctagagcgt
    12001 aacttcacta gtggagctta tagttatgcc cgtctttacc ctaccagctc caactattct
    12061 aaggttgcag aagaatacaa ggacaatatc tattacacac aatcaggctc tgggattgct
    12121 ggtctgggtg tgaatattga tcgccaaagt tacaactata cttctaaaac tacagattca
    12181 gagaaagtag ctactaagaa ggcattgctt aacaaagatt tccgtcaagc cttgaatttt
    12241 gctcttgatc gctcagctta ctcagctcaa atcaatggta aagatggagc agctttagca
    12301 gttcgtaatt tatttgtaaa accagacttt gtttcagctg gtgagaagac ctttggtgat
    12361 ttagtcgctg ctcaacttcc tgcttatggt gatgagtgga aaggtgtgaa tttagctgat
    12421 gggcaggatg gtttattcaa tgctgacaag gccaaggcag agtttgcgaa agctaagaaa
    12481 gctttagaag cagacggcgt tcagtttcct attcatctgg acgttccagt agaccaagca
    12541 tcaaaaaact acatatctcg tattcagtcc tttaaacaat ctgtagaaac agttcttggt
    12601 gttgaaaatg tcgttgttga tattcaacaa atgacaagtg atgaattcct taatattact
    12661 tactatgctg ccaatgcttc atctgaggat tgggatgtat cgggaggagt ttcatggggg
    12721 ccagactatc aagacccatc tacttacctg gatattttaa aaacaactag cagtgaaact
    12781 acaaaaacat atttaggatt tgataatcca aatagccctt cagtagttca agttggtttg
    12841 aaagaatacg ataaattagt tgatgaagct gccaaagaga caagcgactt gaatgtccgt
    12901 tatgaaaaat atgcagcggc tcaagcatgg ttgacagata gttcactctt tattcctgct
    12961 atggcttctt ctggtgcagc accagtgctt tcacgaattg ttccatttac tggagcttct
    13021 gcgcaaacag gctctaaggg gtcagatgtt tacttcaaat atttgaaatt acaagataaa
    13081 gtggtgacta aggaagagta tgaaaaagct cgtgaaaaat ggttgaaaga aaaagctgaa
    13141 tcaaatgaga aagctcaaaa agaattggca agtcatgtga agtaaataat ttctaataga
    13201 actttctctc catgaggaga aggttctttt gggattttta aaggaaataa tatgaaaaaa
    13261 tatattttta tgcgtgtttt gcggtcattg gtttcgattt tcttagtaac gactttgacc
    13321 tacacgatta tctatacctt ggttcctcga aaattgattt tcaagcagga tcctaactat
    13381 aataaaattg caacaacggc tgataaacgt gataactatg aaaatactgt gtttgagcgt
    13441 atgggctaca ttgagtatta cgatactaaa gagttgcaag aaaaggcaag tagcatggat
    13501 tcttctgtaa cagtagaagc aaatgcgacc aataaagcta tttatgaaaa gtacatcaat
    13561 caattaggtc atggttggac tttgggagaa tttactgaaa gtggtcaatt ctatgctact
    13621 cgtgaaattc caatttttga acgtgttttt cacttctatg ctaacttgat tgacattgac
    13681 catacaaata aaatccaaga ccctgaaaat ccagacttga aacgctacct tcgttttgaa
    13741 aatgatccag ctatcggatg gtcattggtc ggttcaggaa ctaaacataa atatctcttg
    13801 tactttaaca gtcagttccc atttgttcat caaaactttg tgaacttgaa tttaggtgac
    13861 tcttacccaa cctatgctaa tacaccagtt cttcaggtta ttactcaagg tcaaggacaa
    13921 accaaaactg cccaagttca gttcccaaca ggtaagaaaa cgtcttctgt aaatatttac
    13981 tcaagaacct acaagtcacc tagtcaggct gactctcgtg aagtagctag ctatgggaaa
    14041 gatgatcctt atacagcgac tgaaagtaat taccaatatc catctatgat tgtcagctct
    14101 gctattactg gtttgattgg tttggttctt gcctatgctc ttgccgtgcc acttggttca
    14161 gccatggctc gtttcaagaa cacttggatt gatagcctct caacaggggc tttgaccttc
    14221 ttgcttgctc ttccaacgat tgccttggtt tacatcgttc gattgattgg atcatctatt
    14281 gcccttccag attcattccc tatcttggga gctggagatt ggcgttctta cgttttacca
    14341 gcagtcatcc ttggtttgtt gggtgctcct ggtacagcca tttggattcg tcgttacatg
    14401 attgacttgc aatctcaaga ctttgttcgt ttcgctcgtg caaaaggttt gtctgaaaaa
    14461 gaaatttcaa acaaacacat ctttaaaaat gccatggttc cgctggtttc aggaattcct
    14521 ggtgccatca ttggggttat cggtggtgca acccttactg aaacagtctt cgccttccca
    14581 ggtatgggta aaatgttgat tgactctgta aaagcatcta ataactctat ggtcgttggt
    14641 cttgtcttca tctttacatg tatttctatc ttctcacgtc ttttgggaga tatttggatg
    14701 actattattg acccacgtat taaattgact gagaaaggag gcaaataatg tctacaatcg
    14761 ataaagaaaa atttcagttt gtaaaacgtg acgattttgc ctctgaaact attgatgcgc
    14821 cagcatattc ttactggaaa tcagtgttta aacaatttat gaagaaaaaa tcaactgtag
    14881 tcatgttggg aatcttggta gccatcattt tgataagttt catctaccca atgttttcta
    14941 agtttgattt caatgatgtc agcaaggtaa acgactttag tattcgttat atcaagccaa
    15001 atgcggagca ttggttcggt actgacagta acggtaaatc gctctttgac ggtgtctggt
    15061 tcggagctcg taactccatc ctcatttctg tgattgcgac agtgattaac ttggttatcg
    15121 gtgtttttgt cggtggtatt tggggtattt caaaatcagt tgaccgtgtc atgatggaag
    15181 tttacaacgt catctcaaac atcccacctc ttttgattgt tattgtcttg acttactcaa
    15241 tcggagctgg attctggaat ctgatttttg ccatgagcgt aacaacatgg attggtatcg
    15301 ccttcatgat ccgtgtgcaa atcttgcgct atcgtgactt ggaatacaac ttggcatcac
    15361 gtactttggg aacaccaacc ttgaagattg ttgccaaaaa tatcatgcct caattggtat
    15421 ctgttattgt gacaaccatg actcaaatgc ttccaagctt tatctcatac gaagccttct
    15481 tgtctttctt cggtcttgga ttaccgatta cagtgccaag tttgggtcgt ttgatttcgg
    15541 attattcaca aaacgtaaca accaatgctt acttgttctg gattccattg acaacccttg
    15601 tcttggtatc cttgtccctt ttcgtagttg gtcaaaactt agcggatgct agtgatccac
    15661 gtacacatag ataggagtag aaatgacaaa agaaaaaaat gtaattttga ctgctcgcga
    15721 tattgtcgtg gaatttgacg ttcgtgacaa agtattgaca gccattcgcg gcgtttccct
    15781 tgaactcgtt gaaggagaag tattagcctt ggtaggtgag tcaggatcag gtaaatctgt
    15841 tttgacaaag accttcacag gtatgctcga agaaaatggt cgcattgccc aaggtagtat
    15901 tgactaccgt ggtcaggatt tgacagcttt atcttctcac aaggattggg aacaaattcg
    15961 tggtgctaag attgcgacta tcttccagga cccaatgact agtttggacc ccattaaaac
    16021 aattggtagt cagattacag aagttattgt aaaacaccaa ggaaaaacag ctaaagaagc
    16081 gaaagaattg gccattgact acatgaataa ggttggcatt ccagacgcag atagacgttt
    16141 taatgaatac ccattccaat attctggagg aatgcgtcaa cgtatcgtta ttgctattgc
    16201 ccttgcctgc cgacctgatg tcttgatctg tgatgagcca acaactgcct tggatgtaac
    16261 tattcaagct cagattattg atttgctaaa atctttacaa aacgagtatc atttcacaac
    16321 aatctttatt acccacgacc ttggtgtggt ggcaagtatt gcggataagg tagcggttat
    16381 gtatgcagga gaaatcgttg agtatggaac ggttgaggaa gtcttctatg accctcgcca
    16441 tccatataca tggagtctct tgtctagctt gcctcagctt gctgatgata aaggggatct
    16501 ttactcaatc ccaggaacac ctccgtcact ttatactgac ctgaaagggg atgcttttgc
    16561 cttgcgttct gactacgcaa tgcagattga cttcgaacaa aaagctcctc aattctcagt
    16621 atcagagaca cattgggcta aaacttggct tcttcatgag gatgctccaa aagtagaaaa
    16681 accagctgtg attgcaaatc tccatgataa gattcgtgaa aaaatgggat ttgcccatct
    16741 ggctgactag gaggaaggaa atgtctgaaa aattagtaga aatcaaagat ttagaaattt
    16801 ccttcggtga aggaagtaag aagtttgtcg cggttaaaaa tgctaacttc tttatcaaca
    16861 agggagaaac tttctcgctt gtaggtgagt ccggtagtgg gaaaacaact attggtcgtg
    16921 ctatcatcgg tctaaatgat acaagtaatg gagatatcat ttttgatggt caaaagatta
    16981 atggtaagaa atcgcgtgaa caagctgcgg aattgattcg tcgaatccag atgattttcc
    17041 aagaccctgc tgcaagtttg aatgaacgtg cgactgttga ttatattatt tctgaaggtc
    17101 tttacaatca ccgtttattt aaggatgaag aagaacgtaa agagaaagtt caaaatatta
    17161 tccgtgaagt aggtcttctt gctgagcact tgactcgtta ccctcatgaa ttctcaggcg
    17221 gtcaacgtca acgtatcggt attgcccgtg ccttggtcat gcaaccagac tttgttattg
    17281 cagatgagcc aatttcagcc ttggacgttt ctgtacgtgc ccaagtcttg aacttgctca
    17341 aaaaattcca aaaagagctc ggcctgacct atctcttcat cgcccatgac ttgtcggttg
    17401 ttcgctttat ttcagatcgt atcgcagtta tttacaaggg tgttattgta gaggttgcag
    17461 aaacagaaga attgtttaac aatccaattc acccatatac tcaagccttg ctttcagcgg
    17521 taccaatccc agatccaatc ttggaacgta agaaggtctt gaaggtttac gacccaagtc
    17581 aacacgacta tgagactgat aagccatcta tggtagaaat ccgtccaggt cactatgttt
    17641 gggcgaacca agccgaattg gcacgttatc aaaaaggact aaactaataa tggttttata
    17701 atttccatgt caatttttat gggaattata aaactttttt gttggactga tttgaaaaac
    17761 tttgaaagct tcctgaaaga
//
LOCUS       DAVAZT010000046        17720 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVAZT010000046 DAVAZT010000000
VERSION     DAVAZT010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17720
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.046"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..224)
                     /locus_tag="VQT45_001550"
     CDS             complement(<1..224)
                     /locus_tag="VQT45_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAM domain-containing protein"
                     /protein_id="HET2359851.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCT"
     gene            262..1038
                     /gene="recX"
                     /locus_tag="VQT45_001551"
     CDS             262..1038
                     /gene="recX"
                     /locus_tag="VQT45_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HET2359852.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINANQLSGDKGPYVLTQKLAQKGISKSTIEEILNDFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYFDAKIAFDELDSQVDEETTQELIFKELDK
                     QYTKYARKYEGYKLKQRLTQVLARKGYDFSDIASALREYL"
     gene            1127..1660
                     /locus_tag="VQT45_001552"
     CDS             1127..1660
                     /locus_tag="VQT45_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HET2359853.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(2100..2856)
                     /locus_tag="VQT45_001553"
                     /pseudo
     CDS             complement(2100..2856)
                     /locus_tag="VQT45_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(2994..4616)
                     /gene="groL"
                     /locus_tag="VQT45_001554"
     CDS             complement(2994..4616)
                     /gene="groL"
                     /locus_tag="VQT45_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HET2359854.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(4632..4916)
                     /gene="groES"
                     /locus_tag="VQT45_001555"
     CDS             complement(4632..4916)
                     /gene="groES"
                     /locus_tag="VQT45_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HET2359855.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(5186..5581)
                     /locus_tag="VQT45_001556"
     CDS             complement(5186..5581)
                     /locus_tag="VQT45_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HET2359856.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(5659..6420)
                     /locus_tag="VQT45_001557"
     CDS             complement(5659..6420)
                     /locus_tag="VQT45_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET2359857.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(6453..7079)
                     /locus_tag="VQT45_001558"
     CDS             complement(6453..7079)
                     /locus_tag="VQT45_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HET2359858.1"
                     /translation="MIFTYNKEHVSDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(7095..7412)
                     /locus_tag="VQT45_001559"
     CDS             complement(7095..7412)
                     /locus_tag="VQT45_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HET2359859.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(7409..7708)
                     /locus_tag="VQT45_001560"
     CDS             complement(7409..7708)
                     /locus_tag="VQT45_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HET2359860.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(7993..8184)
                     /locus_tag="VQT45_001561"
     CDS             complement(7993..8184)
                     /locus_tag="VQT45_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HET2359861.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(8345..9019)
                     /locus_tag="VQT45_001562"
     CDS             complement(8345..9019)
                     /locus_tag="VQT45_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359862.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKL
                     EIVYVK"
     gene            complement(9025..9471)
                     /locus_tag="VQT45_001563"
     CDS             complement(9025..9471)
                     /locus_tag="VQT45_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2359863.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(9573..10088)
                     /locus_tag="VQT45_001564"
     CDS             complement(9573..10088)
                     /locus_tag="VQT45_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET2359864.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVCVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLFLHVS"
     gene            complement(10085..10447)
                     /locus_tag="VQT45_001565"
     CDS             complement(10085..10447)
                     /locus_tag="VQT45_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 family protein"
                     /protein_id="HET2359865.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICSVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(10513..12372)
                     /locus_tag="VQT45_001566"
                     /pseudo
     CDS             complement(10513..12372)
                     /locus_tag="VQT45_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(12389..12859)
                     /locus_tag="VQT45_001567"
     CDS             complement(12389..12859)
                     /locus_tag="VQT45_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET2359866.1"
                     /translation="MDKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVHFLDN
                     REKNQDLVLIKDIEQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQANIKGIGGENKEISQKN"
     gene            complement(12983..13699)
                     /locus_tag="VQT45_001568"
     CDS             complement(12983..13699)
                     /locus_tag="VQT45_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2359867.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(14580..15989)
                     /gene="ply"
                     /locus_tag="VQT45_001569"
     CDS             complement(14580..15989)
                     /gene="ply"
                     /locus_tag="VQT45_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HET2359868.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQHEKITAHSMEQ
                     LKVKFGSDFEKIGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLRQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFESLIKGVAPQTEW
                     KQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTSFL
                     RDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVLTP
                     KAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRKRT
                     ISIWGTTLYPQVEDKVEND"
     gene            complement(16000..16332)
                     /locus_tag="VQT45_001570"
     CDS             complement(16000..16332)
                     /locus_tag="VQT45_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359869.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDYLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(16403..17011)
                     /locus_tag="VQT45_001571"
     CDS             complement(16403..17011)
                     /locus_tag="VQT45_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359870.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(17024..17482)
                     /locus_tag="VQT45_001572"
     CDS             complement(17024..17482)
                     /locus_tag="VQT45_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HET2359871.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            17607..>17720
                     /locus_tag="VQT45_001573"
     CDS             17607..>17720
                     /locus_tag="VQT45_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET2359872.1"
                     /translation="MNYEASKQLTDTRFKRLVGVQRTTFEEMLAVLKTAYQK"
BASE COUNT         5232 a         3942 c         3237 g         5309 t
ORIGIN      
        1 atagtacaag atggcacaat tcgaaattta gacttcttgt tgaccttcag taattttgct
       61 tcaacaaagt tgcgtctaat agaagtaatc tgacaataga tatcttcgcc tttgagagct
      121 cctggtacaa agactaatgt tttttggtaa aagccgattc cctcaccgtt aattcccatg
      181 cgcttgattt ttaatggtat tttttgtttc actttcagat tcatacccct atcttatcac
      241 attttgagtt ataatagagc tatgaaaatc acaaaacttg aaaagaaaaa aagactctat
      301 ctgatggagc ttgataatgg cgacaaatgc tatatcaccg aagatacaat tgttcgtttt
      361 atgttatcga gagataaggt gataagcgaa gaggaattga aagagattca agactttgct
      421 caattttctt atggtaagaa tctggccctc taccacttat cctttaaagc acgcactgaa
      481 aaagaagtca gagaatatct gaaaaaatac gatattgata aaaacatcgt ttctcaagtt
      541 attgctaatc ttaaagaaga taagtggatt aatgatggtc agtacgctta tgctatcatc
      601 aatgccaatc aactttcagg agacaaggga ccttatgtac tgactcagaa attagcacaa
      661 aaaggaattt caaaatctac tatagaagaa atcttgaatg attttgattt ttcggaagtt
      721 gctcaacgtg tagccaataa actattgaaa aaatatgagg gaaaacttcc agctcgtgcc
      781 ctgcaagata agattatcca gaacttgact aacaagggct tctcttattt tgatgctaaa
      841 attgcctttg acgaattgga tagtcaagtt gatgaagaaa cgactcagga actcatcttc
      901 aaggaacttg ataagcaata tactaagtat gcccgaaagt atgaaggata caaactgaag
      961 cagcgtttaa ctcaagtttt agcacgaaag ggctacgatt tttcggatat agcaagcgct
     1021 cttagagaat atctttaata tttccaagtg aaattcacag attttaggta attttatggt
     1081 acaatagtaa atgataaact tataaattgt agaaagttgg ttagttatga agcttccaaa
     1141 agaaggcgac tttattacaa ttcaaagtta taagcatgat gggagtctcc accgaacttg
     1201 gcgggacacc atggtactaa aaacaacaga aaacgccatt attggtgtca acgatcatac
     1261 acttgttacc gaaagtgatg gtcgtcgttg ggtcactcga gaaccggcta ttgtttactt
     1321 tcacaagaaa tattggttta atatcattgc catgattcgt gataatggaa cttcttacta
     1381 ttgcaatatg gctagcccct actatctgga tgaagaagca ctgaagtata ttgattacga
     1441 tttggatgtt aaaattttta cagatgggga aaaacgtctc ttggacgttg aagagtacga
     1501 gcgtcacaaa cgcaaaatga attattctga tgacttggac tatattttaa aagaacatgt
     1561 caaaattctt gttgattgga ttaacaatgg acgtggtcct ttctcagaag cctatgtaaa
     1621 catttggtac aagcgctatg tagaactaaa gaatcggtaa agttgtcaaa ggtcaggaac
     1681 aaaatcctga ccttgttttt ttggtagtat aaaataaatt gtgtaaacac aaaaaggaat
     1741 aaatccatta tagcagagtt acaacacatt tctataaaga aatttattcc tacgactcag
     1801 tttggcatgc ttaacttcct aactcaaaaa caaagcatcg attaatttat ccgttcttct
     1861 tttgaaacag atttgaactg ataattgctc gttttaattt aagaagctct tttgagcaaa
     1921 acttcatttt tttaagagtc caacaatttc tgtctatcgc ttttctacta gcaaaaaacc
     1981 tcccttgagg caagttttca tttatatatc taatttcgta acagtatagt aaaatgaaat
     2041 aaggacagtc aaatcgattt ctaacaatgt tttagaagta gaggtgtact attctagttt
     2101 caatctacta taaatttgat atgagaatag tctttctcaa catccttatc caacaagcat
     2161 gctgtggcgt ccttcttaac ttgaaccagg tcaatattct gggcttgggc tgccatagac
     2221 gcagccacaa taacattgac gatagatatc atactcctca cacatctcta ctgaacgttt
     2281 gtagccttga tttttcttga aatcgttggg aagatagtgg gtcgtgtaaa ttttttgcac
     2341 atcgattccg atgctattga tggtttgaga attcttatga ggactgatgg tcaaggctga
     2401 accaaagtag tcaaagccca agtccatagc cacttgcgct gttttatcca gtcggtagtc
     2461 aaaacaaacc ttgcaacggt cgccaccttc gggctcctcc tctagtcccc taactagttt
     2521 tcggtattaa ttgggttcgt agggagcttc taggtactga accgtatttc ctgtccgatc
     2581 attaaaatca ctaacaaatt tcttgatgac atagacccgc ttatggtatt ctactttggg
     2641 atggatatta gaattggcaa aatagatggt cacatctgca tacttggtca aatattctag
     2701 tgtataggta ctacaagggg cacagcaaac atgcacgaga atggttggcc gctgctcatt
     2761 tttctcccat gcttgtacca ttttctgcat gacacggtca taattaatct tctgattggg
     2821 gggcatcttg cacagaattt cttctacatc gatcatgttc ttctcctttt tctagtctta
     2881 ttttatcata taagttagaa gagctcaaat caatttagaa gtgaatatta taaaaagaag
     2941 ggttagtcat tccctccttt tgtgtttttt ataagttgtt ttctatagaa agcttacatc
     3001 atcccgccca tcatacttgg atccattgct ggagctgggg ctactggttc tggtttattg
     3061 gctacgactg cttctgttgt caaaatcaag ctggctacag atgctgcatt ttgtagggct
     3121 gaacgactca ctttaactgg atcaatgata ccttgatcaa tcatgttaac ccactcgcca
     3181 gttgctgcgt tgaatcctat accaagctca gcatttttca aacgatcgat aacgatagat
     3241 ccttcaaatc ctgcattgtg agcaatttga cgaacgggtt cttccaaagc acggagaaca
     3301 atattacgtc ctgttgcttc atctcctgtc aattccaagg tagcaacagc tggaatcaca
     3361 ttggcaagag ctgttccacc acctgcaaca ataccttctt caacagctgc acgagtagcg
     3421 ttgagggcat cttcaatgcg gagtttcatt tctttcaact cagtttcagt tgcggctccg
     3481 accttaataa ccgctacacc acctgacaat ttggccaagc gttcttgcaa tttttcacgg
     3541 tcaaattcag aagttgtagt ttcgatttga gacttgataa ccgcaacacg gtgagaaatc
     3601 gcttcaggat ttcctgcacc ttctacaata accgtgctat ctttgtccac ggtcactctc
     3661 gctgcttgac caagagcttc aattgtcgca tctttcaact caagaccaag gtcttctgtg
     3721 ataactgttc cgcctgttaa gatggcgata tcttcaagca tggctttgcg acggtcacca
     3781 aaaccaggtg ccttgactgc tactacgttg aaggttccac gaatcttgtt caaaacaaga
     3841 gttggaagag cctcgccatc cacatcatcc gcaataatca agagtggacg attgctttgg
     3901 agaatgcttt ccaaaagtgg caagatttct tggatattgg aaattttctt gtctgtaatc
     3961 aaaatgtacg gattttcaag gtcagccacc attttttcgc tatcagtcac catgtactgt
     4021 gaaaggtaac cacggtcaaa ctgcattcct tctacgactt caagctctgt ttccatacca
     4081 cgtgactctt cgatggtgat gacaccgtct ttgccaactt tttccattgc ttcagagatg
     4141 tactcaccaa ctttttcaga acgagaagat acggctgcaa cttgagcgat agcttcttta
     4201 ttggcaacag ggatggcgtt gtttttcaaa gcttcaactg ctgcggcaac tgctgtttca
     4261 atcccacgac gaataccgat tggatttgca cctgctgtga cgtttttgat tccttcacgg
     4321 acgattgctt gggtcaaaac agttgcagtt gtagttccat cacctgcgat atcattggtt
     4381 tttgaagcca cttctgatac caatttggca cccatatttt caaaatggtc ttctaattca
     4441 atttctttgg caatagtcac accgtcattg gtaatcaatg gtgagccaaa tgatttttca
     4501 agaacgacat tgcgaccttt tggtcccaag gttactttaa cagtgtctgc aaggatatcg
     4561 acaccacgga ccatagctga acgggcatct gatgaaaatt taatttcttt tgacatactt
     4621 actttctcct tctattcttc aatgattgcc aagatgttag cttcgcctac gatgatgtac
     4681 ttttcatcgc catctttgac atcaagacct gcgtgggctt caactaagac acggtctcca
     4741 gttttaacac ttggagcaac caagtcaccg ttcaaggtac gaacaccttg tccagtagcc
     4801 acaacttggg ctgttttggt tttttcttgg gctgaacctg cgagaacaaa gcccccaacg
     4861 gtttgttctt tttcttctat ttttaagacc acacggtccc ctaatggttt caacatctga
     4921 tttcctccat aatgagatag atattattag cgctctttat acctgagtgc taattcatag
     4981 ttctattgta tcacttagtc agaaataatc aagaaaaaag tctgactttc tcaagataaa
     5041 aagcctgaga ccaactcaga ctttttaatg tttatactca atgaaaatca aagagcaaac
     5101 taggaagcta gccgcaagct gctcaaagca ttgctttgat gttgtggata aagctaacgt
     5161 ggtttgaaga gattttcgaa gagtattaaa atggcaattc ttcctcttcc aagactaaat
     5221 ctgccaaatc ttggcctgca ttattttcac gcatggcacg ttgagcacga ctttccaaga
     5281 gttggaatcc tgttacaagt acttcggtca cgtagttcat ttggccattt ttctcaaagc
     5341 gacgggtacg caattctcca tcaacggaaa tgagactacc tttggttgcg tagcttgcca
     5401 aagtttctgc tagtctgccc cataggacca tattgacaaa atcagcttca cgttcaccgt
     5461 tttggtcttt gtaacgacgg ttcacagcga tagttgctcg cgctaccgac ttgtcattgt
     5521 tggttttgtg caattctggt gtagacgtta aacgcccaat catgataact ttattataca
     5581 tattttcttc ctcctactta tctattcgta ggaaatcaaa aaaagttaca gaaatttgta
     5641 acttttcgag gaaatttctt attttttatg aatcatgaaa cctgtcgcct gttgattggc
     5701 cataatggtc atatctgtaa tctgaacacg gcgaggctga ctggtcacat agactactgt
     5761 gtctgcaata tcctgagctt gcaaggcttc tattccttgg taaacggacg cagctcgctc
     5821 tttatcacca tgaaaacgaa cagttgagaa atctgtttcg acaatcccag gctgaatggt
     5881 tgtcaccttg atatccgttg cgatggtatc aattcgcagt ccatccgaaa aggtcttaac
     5941 cgcagccttg gtagctgagt aaacagcggc accagcatag gcgtagattc ctgcggttga
     6001 ccccatattg ataatatgac cttgattgac ttttatcatt gctggcaaga aacagcgagt
     6061 aaccgccatc agacctttaa cattggtatc caacatggtc aacatatcca actcctcata
     6121 gtcttgatag ggagccaagt caagagccag tccggcgttg ttgaccaaga tatcaatcct
     6181 ccctatcgtt tctagaatat cagagcaaac agtcttcacc atgaccatat ccgtcacatc
     6241 tagtggaaaa gtccagacgg tttgatttgg aaagcttact gcaaactccg acttgaggat
     6301 ttctaatctg tctatccgtc gtcctgttag aacgacatcc tcaccctgct ccagataagc
     6361 acgcgcaatc gcttcaccga ttcctgaggt tgctcccgta atcactacat tttttgccat
     6421 cttatttcct tctatcagat gctgacaagt tcctaggcag tccagtgttt cgctgggtcg
     6481 aacggtgttc cgacaacttg gtcttctgat aattcaagca ccccacgttt ttgcggagca
     6541 tttggcaaat gcaattcacg aggactacac atcatcccaa aactcttttc accacgaagt
     6601 tcgcctggga aaatgaaatt cccttttggc atcatggcac caggaagagc cacaatggtt
     6661 ttcaacccaa cacgcgcatt aggtgctcct gcaacgattt gcactatctt gtcacttgcg
     6721 actgcaactt ggcagatgtt gaggtggtca ctgtctggat gagctaccat ctcgacaatt
     6781 tcaccaacaa caaacttagg ttccttatca ttaacaattt cttctgtaaa accttccgcc
     6841 tgtaattctt ggttcaaacg agcgacttgc tcatctgata aaaagacttg accgcgctct
     6901 gcaatttcaa acaagctcga aacctcaaaa atgttccaag ccactgtttc cccattttct
     6961 ttgaggaaaa cacgggctac cttgcctttg cgttccacat tcagtttggc atctccgcta
     7021 tttttcacga tgaccataag gacatcactg acatgttctt tgttatacgt aaaaatcatt
     7081 gtttcctttt tctcctattt caatcctgct aaaaaatcgt taatttgctc cttactttta
     7141 cggtcgcgat tgacaaaacg accgatttcc ttgtcctttt ctagaacaac aaggctagga
     7201 attccgtaaa catcccagag tttggccaaa tccatatact gatctcggtc cattcgaata
     7261 aaggtgaact ctggattggt ctcttcaatc tctggtaagg caggataaat ataacgacaa
     7321 tcgccacacc agtctgccac aaaaaggaag accttcttgc ccgctttttc cactaaagat
     7381 gctaattctt ctaaacttgc tggctgtatc ataagacttc ctcctcatag actaggtctt
     7441 cattttcata gacaaaggta taatgacggc catcctcaaa aatgacgcca ccaaccaagc
     7501 tctccagact gctttcgtaa acttgaacat aaagggtcgc aatttccccc atgtcggaaa
     7561 aatggtctcg cacaatctct gtcaactctt cctgagtctt catgagctta cggtcatctg
     7621 caactttttt cgtagcaaga gcaaggcttc cgatacctag cagagccaag cctgccatcc
     7681 acattttttt agctttcata ccattcattt taacacaaaa aaggcttcag gacaaatgag
     7741 gaagcagcag aaaagcaagt aaaaagcctc ttcctttaag gaaaaagact tcttatacta
     7801 agagcaaact aggaagctag ccgcaggctg ctcaaaacac ggttttgagg ttgtagataa
     7861 ggcgacgttg acgtggtttg aagagatttt caaagagtat tattcttatt gccaggcacc
     7921 taagttgcca acgtagtaac tatcaggtgt gtaggtattg cgaagcatct tacctgatga
     7981 agccagataa tactacttgc cattgtcttt gacccaatca ttcgcaatca tggaaccaga
     8041 agaacttaca taataccatt ctcccttgtc ataaacccaa gtactgactt tcatggttcc
     8101 tgagcaatta aaggcaaaaa aactgtccaa tatcattcgt tttttaaaag catttgacac
     8161 tacatcatct acgctgtagt acatagatac atcaaacgta aaagccaaaa tatcgaaaaa
     8221 tatacaactt ttaaaggcag catttcattt tttaaagtct aacaaccata gaactgaaat
     8281 cagagcaagg catcaatttc ctactcttag tacgtctatt ttgatggttg aagtgaagat
     8341 ttttttattt aacgtagaca atttccaact tcccaaaagc cacatctcca cggatagtca
     8401 aggttttgct ggttggggct acaggagcgt cagccttagc tgcaccaaag gaggtttcta
     8461 ctttcaaatc tacacgccag tgttgtggaa catagacggt tgcattcccg aaggccactt
     8521 caatatttaa agttgcaaaa tcacctagca tctctgcatt atcatagtag attttagcat
     8581 ccccaaaagc gacttccact tggtcatcta cgagatcttg atcttgctta tagaaggtcc
     8641 cgctaccaaa agcgacttcc ttatccgtga cgactgtttt tttcccattg taccaccatt
     8701 ttttttcatt ccagaactta cttgaatgcg tcagataacc aacaccaagt accaccaaga
     8761 tgctagccca aataagagaa tgattggtaa ctggtaacaa gtcataagcg taatttgcaa
     8821 tgatgagcgc cagtaaacct gtaaaaactg ccgaagtgag atgacgtcta aggatggact
     8881 caatggactt ataagcaaaa aaaacaatac ctagtaaagg ccatatttta ccatccaaag
     8941 aaggaattcc aaaattccct tgcagcaaga tccaagctgc taaaaccaac aaaacaatac
     9001 caaatgcttt ctttttcatg ttttttacct catgtttctt agattttctt ttaggaggga
     9061 ttggtaatgc cgtgagacat gaacctcctt gtgcgtctga taaaaggaaa tggtgcccgt
     9121 tcctgaaaag gacttgtcca ctgagtaaat ctgacggatg tttgcgatcg ttgacttgga
     9181 aactcgatta aaatagcgag gcaagataga ctccaactca tagagcttga ggcgaacctc
     9241 ataagcttcc ttctggttat gagcgtagat cttgctccct tctgtttcaa agaagagaat
     9301 ttctgacagg tctagataat attcacctgt ccccttgtaa aaagtcaacc tcggagcctt
     9361 tgactcttgc aagagccgtt gcaagtctgc aatttcatct gtcaaagtgg gggtcttgat
     9421 gacaatttca gtctcctcta aattgccgtc aatctcaatt cgtaacttca tcacatctcc
     9481 tttctgactc tactatatca aagctaagtt aggaatacaa gggcaaaaaa gcaagtggtc
     9541 aatttgaagc agtaagtggt tgtaggacta gcttaactta catgtaagaa taggaagaaa
     9601 aggaatcccc acaccaaacc acaagcatag ccaaccaaga catccttggg ataatgaaca
     9661 ccccctaaaa ccctcaccaa ccccagcaaa gctgaaaaga tcaagcatac taagccaata
     9721 ggtagactag catgcagaca ggccatggag atgatagttg ccgaaaagac atggcgactg
     9781 ggcatcgacc gtcccgaact atccttatca agaaggggac agatatccca agtttcataa
     9841 ggtctcgggt gattgatttt cttacgaaac agggacaagg ccacaaaacc tgatgcagga
     9901 ataagcacac aaaccccaac ttgctgacca agtcctagtt gcaggtaagt ggtgactagc
     9961 aagatcagat agaccagggg catggcgact gtcatcaaac gattgaaact gcgtaatagg
    10021 aataaaagaa ttggacgact agttagtctg gagctgatat ttcgatacca ttcttgataa
    10081 tttttcattt atgcttctca tacttttcta gaacttgttg agatgttttc cccttggcaa
    10141 gccaatccac tagcttgtcc aagcgacgta tttcctgcat cagaggatca tcaatttcct
    10201 caatacggac actgcaaatc ttccctgtaa ttgcaattcg ttcagggaca taatatggtg
    10261 cttgtctaaa aaaatctccg taagtaacat ccctatccag acaagcaaga acatcactca
    10321 cttcataccc tgtcaaccaa ctggtcactt ggtgaactga ctctgccttt ccaccctttc
    10381 gctcaacttt tgcaatcaag gctaagtaga cagcagcaaa tttcatattg tataatttct
    10441 gactcatact tctctctttc tatgtgtact agtataaata agaaaaagaa ggccgtcaag
    10501 ccttcttttg atttattctt ctgcttcatc ttctgtaaat tgactattgt acaagtcagc
    10561 gtagaagcca ccttgcgcca tcagttcctc atagttgcct tgctcgatga tatttccatc
    10621 tttcatgacc aagatcaagt ctgcatttcg gatggttgac aagcggtggg caatgacaaa
    10681 ggatgtgcgt ccttccatca aacggtccat ggctttttgg atcaattcct ctgtccgtgt
    10741 gtcaacagaa gaagtcgcct catccaaaat caaaagcggt gcatccttaa gaagggcacg
    10801 agcaatagtc aatagttgtt tttgtcctac agacaaggtc acggtgtcat ccaagatggt
    10861 atcatagcca tctggcaagg tcataataaa gtggtgaatt cccacagcct tactagcttc
    10921 catcattcgt tcatcactaa tccctatttg attatagatg agattgtctc gaatagttcc
    10981 ttcaaagagc caggtatcct gcaagaccat tgaaaaggca tcatgcactt ctgaacgcgt
    11041 catagccttg gtatccacac catcaatgtg aatacttccc ttatcaatct catagaattt
    11101 catcaaaaga ttgacaatgg ttgtcttacc agtcccagtc ggcccaacaa tggcaacctt
    11161 ttgaccagca tgaactgtcg cagagaagtc atagtcttga acattgacac cgtccaccag
    11221 aatttctcct gctgacacgt cgtagaaacg tggaatcaga ttgaccagag ttgatttacc
    11281 agaacctgtt gacccaataa aggccactgt ttgaccagtt tctgctttaa agctaacatg
    11341 ttcaataact gcctccgaat ttgccgcata gcggaaggtc acatccttaa actcgacctg
    11401 acctttgaag ttttcatcag tcagctgcac ttgaacaggg ttttggatag aagaatgcaa
    11461 atctaaaact tgattaatcc gcttagcaga gaccatagtt tggggaagaa cgatgaagag
    11521 tgctcccatg agaaggaagt ccatgacaac ctacatggca taagacatga aaacaatcat
    11581 gtcactaaag agaggcagac gcgctatcgg agcagcgtcg ttaatcacat aggccccaat
    11641 ccagtaaatc gccacactca aaccacttga aatccccatc atgataggat tcaaaatagc
    11701 cataagacgg ttgacaaaca aatttaaacg ggtcaattca tcatttactg ctgcaaattt
    11761 ttcattttga taatcctctg cattgtaggc acgaacgaca cgaatacctg ttaaactctc
    11821 acgagtgata ctgttcagtt tatctgtcag cccctgaatc aaggactgtt ttggaaaggc
    11881 tagcgtcatc aaaacggtcg tcatcaggac gttgacaatc actgccacaa gtacggccca
    11941 gagccagtat tctgaatgac ctaaaatctt cccaatagcc cagatagcca taattggacc
    12001 acacgttacc acttgcaagt ccatagtaat caacatttga acttgagtaa tgtcattggt
    12061 agtacgcatc aagaggctag gaattgaaaa tttcttaatc tctgtctgcg agtaatccaa
    12121 aactcggtta aaaatatcac ttctcagcct actagtataa gaagccgcca ctcgggatgc
    12181 aaaaaatcca actgcaacta cggacaagaa ggcaagaaag ggcattccca tcatcatgct
    12241 tgccggctgc cacaactcat ctaaattagt tccttgacta cctagcaaat ccgtaatttt
    12301 cgagatatag gtcggcactt ccaactctag atagaccgaa aagcaagtaa agagaatggc
    12361 tagtaaaatc atcccccatt cttttctact aattcttttg actaatttct ttattctctc
    12421 ctcctattcc cttgatattt gcctgtagtt gaccgagaac tttctcaaaa atcagtaatt
    12481 catcttcatc aatgtcttcc atcaactgct tgtctatgcg ttcaaaaaaa gccttaacct
    12541 gttgcatctg agaacgtgct ttgtccgtca gacgaacaaa cttagcccgc ttatcaacag
    12601 gactcgcctc caattccacc aaaccatttt gcactatacg cttaaccaga ttactagcaa
    12661 cagacttggt aatattgagt tcctgctcga tatctttaat caagaccaag tcttggtttt
    12721 tctcgcgatt atccaaaaaa tgcacaacct gaccttgcgg cccacccata aattcaatgc
    12781 cgcaacgttt ggcttccttt tgcaccatca ggtgaatttg atgaccaaaa cgcttaaaga
    12841 ctaacatcgg tttatccata atctccccct tctaaataaa aatagttctc tggagaataa
    12901 ttaaatttct atgagaacta ttttcttgat taaaaaaatc ccaagtgatt ttctcactta
    12961 ggatcatgtt ctataggtta aattaaaacc catctacgtt cgtataaatc ttttggacgt
    13021 cttcgtcgtc ttcaagaacg ctgtaaagtt tttcaaaggt ttcaaggtct tcgcctgaca
    13081 attccacttc tgactgagga atcatttcca attcagtcac ttggaattct tcaataccag
    13141 actcacggag ggcaacgata gccttgtgaa ggtcagttgg cgctgtgtaa actgtgattg
    13201 taccttcttg tgcttctacg tcatccacat ccacatccgc ttcgagcaat tgctcaaaga
    13261 ctgcgtccgc atcttcacct ccaaatacaa taacaccttt gttgtcaaag aggtaagaaa
    13321 cagaacctga agcgcccatg tttccgccgt ttttaccaaa ggctgcacgg acattggctg
    13381 ctgtacggtt gacgttagaa gtcaaagtat ccacaattag catagagcca tttggcccaa
    13441 aaccttcgta acgtccttct gtaaaggttt cgtctgtgtt tcctttggct ttatcaatcg
    13501 ctttatcgat aatgtgtttt ggcacttggg cttgtttagc acggtcgata acgaatttca
    13561 aagctgagtt tgattctgga tctggatcac cttttttagc tgctacatag atttctacac
    13621 caaattttgc atatacttta gagttggctc catctttagc cgttttcttg gctacgatat
    13681 tggcccattt acgtcccatt aggaatctcc ttttttcaca ttttaatctt tcttattata
    13741 acacaagttt ttttgatttt cactagagga aatggatttt attagcaaat caagctagga
    13801 tagcacttta cctgctaaga tggtcttgcc tttctatctt tatcaacaga cactcatcca
    13861 cattcaaaaa acaaactaga ccattatctg caaatagaaa gtttcagcca agtttgacaa
    13921 agtcagctca aattactgtt tgaagtttgt agatataagc gacaaaaaca atcatactgc
    13981 accttttgtt gacagtctac tccagacata tcatagttca agtaaatact ttgaaatcca
    14041 acagttctta taggcgctat tgtattctaa gaaatcaata gaagagtttc taagcaaacc
    14101 tctaatactc aataaaaatc aaagagcaaa ctagaaagct agccgcaggt tgctcaaaac
    14161 actgttttga ggttgcggat agggctgaca tggtttgaag agattttcga agagtataat
    14221 ttacgtgttc ctaagatgga gaagttagac tagtacactg gcacttctaa accattgcta
    14281 gcaattgatt tgttcatatt taatttcatt ttttccataa atgggtatta gatataaaca
    14341 gcaaaatatt tccgatacgt gtcattcttg aatttccaat catctaaaac aagtaaagga
    14401 taatcaatcc cctgtatatc aaggaattgg ctaccctttt tactttttta cacatcctgt
    14461 ttgatagact cattttaaca tcacgagcat actccaatgg aaatcgctag gcaagagata
    14521 aactttcaga tattcgcaga gagctcatcg cctctttttg tcgcaaacat tcttctctcc
    14581 taatcatttt ctaccttatc ctctacctga ggatagagag ttgttcccca aatagaaatc
    14641 gtccgcttac gcactagtgg caaatcggtt ttttcataaa ccgtacgcca ccattcccag
    14701 gcaagcccgg tacactctct aattttgaca gagagattgc gaacattccc ttttaaagga
    14761 atactagtgg taaagtgagc cgtcaaatcc tgcccatttc tgtcccaagc cttaggagtc
    14821 aagacttcct tgccttgatg atcataggat aattcatccc aagtaatata atattgggca
    14881 acataggcac cactatgatc cagcagtaaa tctccgtttc tgtaagctgt aaccttagtc
    14941 tcaacatagt ctgtactgtt ttgaaaggtc gcaactacat tgtcacgtaa aaaagaagtt
    15001 gtataggaaa tcggcaagcc tggatgatcg gctgtaaagc gactgccttc ttgaatcaag
    15061 tcctctacca tatccacctt gcctgttaca actcgggcac ccgaacttgg gtcgccccct
    15121 aaaataaccg ccttcacttc tgtattgtcc aaaatctgct tccactctgt ctgaggagct
    15181 actcctttta tcaaagattc aaaagcagcc tctacttcat cactcttact cgtggtttcc
    15241 aacttgagat agacttggcg cccataagca acactcgaaa tatagaccaa aggacgctct
    15301 gcagaaattc ctctctgcct taaatcctct accgttacag tatcttgaaa cacatctcct
    15361 ggatttttaa cagcatctac gctgactgta taataaatct gcttaaaatt aacaatctga
    15421 atctgctttt cgcctgaatg gacagagtta aaatcaatat caagagaatt ccctatcttt
    15481 tcaaagtcag aaccaaactt gaccttgagt tgttccatgc tgtgagccgt gattttttca
    15541 tgctgcattc tagctgggac attattgacc tgaccataat cttgatgcca cttagccaac
    15601 aaatcgttta ccgctccgcg aacacttgaa ttgctggggt cttccacttg gagaaagcta
    15661 tcgctacttg ccaaaccagg caaatcaata ctataagtca tcggagcacg atcgaccgca
    15721 agaagagtgg gattattctc taacaaggtc tcatccacta cgagaagtgc tccaggatag
    15781 aggcgactgt cgttggtagc tgttacagaa atatcacttg tatttgtcga caagctccgc
    15841 ttctttcttt cgataacaac aaactcatcg ggtagctgat taccctcttt gatgaaacga
    15901 ttttcaatac tttctccctg atgggtcaag agtttctttt tatcgtaatt catagctagt
    15961 ataaagtcat ttactgcttt atttgccatc ttctacctcc taataagttc ctggattgag
    16021 ttgcataaac tcagacttgt tcagcgaaat cagccgtggt tggactaagt aatccaaaat
    16081 ttcctcgtac aattcttctg agacattgcg tcgccgtctg gctaaataag aagtcggaat
    16141 gaccgtatta tccaacataa ataccttatc taagtcaatc aaggttggtc ttgtaaaagg
    16201 attacgagct agatccggct cttctatcat aaagttcttg accaaacgtc tggtcaagag
    16261 agctggtttg aaggtctgat ttttaaccaa ctctttgttt ttagtcatgc tgttgtcaat
    16321 acagatatac atatgattct tcacagccaa atcgctacta atagtcggaa aaggcaaata
    16381 aagagctaca acatctcctc tcttaatcaa gcaagagcac ccccttttct cctaatgtaa
    16441 catagacagg attgaccaag tcttctgatt gactcagaat ttccaaagtt tgagtttggc
    16501 gcgctgtcaa tttagtagca tcttgtctct tcaatacaaa atgcttgtcg ccaataacct
    16561 tgacaatata atccttctcc aaagctgact ggtaaatcca catcagatgt tgtctgtcct
    16621 gagaactcaa gagagaagga ttttcaagcc tcccgatagt ctgataaaaa tcaaaaacag
    16681 gagctaactc ctgccaatct gattggctag ttgtcaaggc tagaaaaagg gctttgcgag
    16741 ctgatacttc ttggttagcc ttgagagtta ctttcccctc caagtttttt agaaatcggg
    16801 aaactccaga aagcaaattt ttctctaact gcgagaaata aaaacctttc gttcccagac
    16861 ataagtcttt catgtcgctt tctctagcaa ataagagctc aaacatttga tagtaaaaga
    16921 aaaatatctg gcactgggtc gcgctcatct tttccttatc ggcttctttt tttaaccaga
    16981 gcaagggcga caggtagctg gattgagaca tttcctctac ctcctactct tttttaactg
    17041 gagcatctgc actagctgcc acttcttttg actggatact ttcccactgg ttaatctcct
    17101 ctgagataag accttcgcat gtcttgacaa atagggcaaa agccttggtc tttcctgcat
    17161 atttctccgt ttggcattga tagaggaatt tttctttctc caggagttgc gcagtttttt
    17221 ggtaagaaat ccaattttcc tttgcattat acaaattgat aatcccctca cacagcaagc
    17281 cgagactgga taaggcaacc gaaatcaaac ggtagcgatc acctggcata ggaatagcac
    17341 aaaagacagc tatgaggaaa cctgccacga tttctgttat ttttaatacc ttatagcgcc
    17401 tacgatgttg aacgcttttc tttaaaaaat gagctatctg tacgtctaat cgctctgtca
    17461 ggtacatttc ttctggcgtc atattcgtaa ctcctttcat ttactttgat aaccatagta
    17521 taacatattt gaatatcaaa gtatagtaaa aactggacta taacttatta gactccctgc
    17581 gaaacaaaat atggtatagt agttctatga attatgaagc aagtaaacaa ttaactgata
    17641 cacgatttaa gcgtcttgtt ggtgttcagc gtaccacttt tgaagagatg ttagctgtat
    17701 taaaaacagc ttatcaaaaa
//
LOCUS       DAVAZT010000047        17282 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVAZT010000047 DAVAZT010000000
VERSION     DAVAZT010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17282
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.047"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..692)
                     /locus_tag="VQT45_001574"
     CDS             complement(<1..692)
                     /locus_tag="VQT45_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HET2359873.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSYRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDG"
     gene            complement(803..1057)
                     /locus_tag="VQT45_001575"
     CDS             complement(803..1057)
                     /locus_tag="VQT45_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359874.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRITNRLANDLNNVLKQV
                     DKDTPNTPTWLNSAASKAKDDDRVYKLLKTLIPGENYLSC"
     gene            complement(1415..1948)
                     /locus_tag="VQT45_001576"
     CDS             complement(1415..1948)
                     /locus_tag="VQT45_001576"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2359875.1"
                     /translation="MTIFKEQESEKVAEFLDILDNLKDLPIVYIDETGINRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(1935..2261)
                     /locus_tag="VQT45_001577"
     CDS             complement(1935..2261)
                     /locus_tag="VQT45_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2359876.1"
                     /translation="MAYNTDFKQGALDSIKGGHRHVEAAKVFWCWRQNSLHVGKERRE
                     QRNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIAAHFDCAVPSVWAALKQIKVTL
                     KKDDDL"
     gene            2495..4213
                     /locus_tag="VQT45_001578"
     CDS             2495..4213
                     /locus_tag="VQT45_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HET2359877.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPKEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            4324..4671
                     /locus_tag="VQT45_001579"
     CDS             4324..4671
                     /locus_tag="VQT45_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET2359878.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(4949..5785)
                     /locus_tag="VQT45_001580"
     CDS             complement(4949..5785)
                     /locus_tag="VQT45_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2359879.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(5798..6427)
                     /locus_tag="VQT45_001581"
     CDS             complement(5798..6427)
                     /locus_tag="VQT45_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2359880.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLDNLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(6437..7078)
                     /locus_tag="VQT45_001582"
     CDS             complement(6437..7078)
                     /locus_tag="VQT45_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2359881.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(7224..8453)
                     /locus_tag="VQT45_001583"
     CDS             complement(7224..8453)
                     /locus_tag="VQT45_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HET2359882.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEESENLLT
                     KWMIARSYQEMDDLDTAYEHYQELIGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(8443..9609)
                     /locus_tag="VQT45_001584"
     CDS             complement(8443..9609)
                     /locus_tag="VQT45_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET2359883.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            9753..10766
                     /locus_tag="VQT45_001585"
     CDS             9753..10766
                     /locus_tag="VQT45_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HET2359884.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(10811..11230)
                     /locus_tag="VQT45_001586"
     CDS             complement(10811..11230)
                     /locus_tag="VQT45_001586"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HET2359885.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDQVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(11241..12647)
                     /gene="atpD"
                     /locus_tag="VQT45_001587"
     CDS             complement(11241..12647)
                     /gene="atpD"
                     /locus_tag="VQT45_001587"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HET2359886.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(12733..13611)
                     /locus_tag="VQT45_001588"
     CDS             complement(12733..13611)
                     /locus_tag="VQT45_001588"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HET2359887.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(13627..15132)
                     /locus_tag="VQT45_001589"
     CDS             complement(13627..15132)
                     /locus_tag="VQT45_001589"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HET2359888.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALIHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(15147..15683)
                     /locus_tag="VQT45_001590"
     CDS             complement(15147..15683)
                     /locus_tag="VQT45_001590"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HET2359889.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(15683..16177)
                     /gene="atpF"
                     /locus_tag="VQT45_001591"
     CDS             complement(15683..16177)
                     /gene="atpF"
                     /locus_tag="VQT45_001591"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HET2359890.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(16191..16907)
                     /gene="atpB"
                     /locus_tag="VQT45_001592"
     CDS             complement(16191..16907)
                     /gene="atpB"
                     /locus_tag="VQT45_001592"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HET2359891.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(16942..17142)
                     /locus_tag="VQT45_001593"
     CDS             complement(16942..17142)
                     /locus_tag="VQT45_001593"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HET2359892.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
BASE COUNT         5222 a         3785 c         3096 g         5179 t
ORIGIN      
        1 ccgtcagtag tagtcatgct actgagtttt ttatctgtga cattgtagct ggtaccaatc
       61 agttgttttt tattggtaat gtaggttccg tcactttctt tttctccaat tccagtatca
      121 tttttcaatg atagcaaacg cccttgttca tcaacatagc gaactttcac attttctgag
      181 attagttctg ccaattctga ggtttttttc tttttcttga tttcttcggt tattttccct
      241 ttctcttctt cgggaatatt tagttttgga atgatttttt caacaacggt tcgtgatggt
      301 tccacagtat cttggatgac tgaaaagtca gctagaattg ggagattata ctgaacacgg
      361 taactttgag tgtttactcc tactctttca ttattctctg aaaatacttg tacggtataa
      421 gaaacaacat cttttcctaa tagaacatcc ccagtagaga aatagccgcc ttttcctagt
      481 ttgctatctc cagagcccac ttctttccta attttatcag atagtttttt accagtcagt
      541 acattcgttc gcacaatccc tttgtctacc cctacaaagt gggagaactt tttgaactct
      601 tcagaaccag atctagccca accattatta agggcatttg cttttgtatt tgtattctct
      661 ctcaaaggtt tggcgattag aattatattc atcggcactt agagttgctg ctatatctga
      721 ctcttgaata ccaacttcct tactaccatt tctagcggca gtatatgtgt atttatctgt
      781 ttctacttct agctgattat ccttaacatg ataggtaatt ttctcctggt ataagagtct
      841 tcagtagttt atatactctg tcatcatctt tagctttaga agcagctgag tttagccaag
      901 ttggggtatt aggagtatct ttatcaacct gtttcaagac attattcaag tcatttgcta
      961 gcctattggt tatcctcact gtgaaagttt tcttccagtc tgaaccactt ttattagact
     1021 tagatatgct catgaaatcc tggtcaacat tcaacacaat atcgccttgt tttttagcat
     1081 cttccgttgc ttctgcttca aattgatcat ggagtttttg ttgctctggt gtatagtttt
     1141 tttatttaca cgatttaatg tactattttt tattttagta ttaagaactc cattaatacg
     1201 atttttaaac tctgcttcaa aaaatccctt aatttgttgg tgcgcaagtt caacattcaa
     1261 acctttctta tacaagtctt cattctgata caagtcttca ttctgaacga tttcggctac
     1321 acggtgaatg gtttgatcgt ataccgtctt ctcttaacca gcagtatcct tagttttaat
     1381 gactactcga taggttcctt tagaaccgtt atagtcatct agttttaaaa aagcattcca
     1441 aacattcaaa aatagttgga acttccctta ataaatccgt cactttcttt ttcaagatag
     1501 cccaagcttg ctcaatagga ttcaaatccg gtgaataagg tggtagaggt aagaaaaagt
     1561 gtttatcttg gatgcagagt tcatccaaaa tgttcttggg atgaaaacta gcattgccca
     1621 tgacaataac atgaggtgtc ttcaaagcag gtaggagttg cgttttgaac cactccacaa
     1681 agaaatcgct tgtcatgctt ttcttgtaaa tcatgggagc tataaactct ccgtctactt
     1741 gtcctgcaac aattgaagtt cgctcaaaac gacgtccgct aatcttttca tagactttct
     1801 cccctctagg agcccctgca taaggacgat agaggtagcg gttgattcct gtttcatcaa
     1861 tatatacgat tggtaaatct tttaggttat ccaaaatatc aagaaactca gcgactttct
     1921 ctgactcttg ttccttaaag atcgtcatct ttttttaaag tgaccttaat ctgctttaaa
     1981 gctgcccata ctgaaggaac agcacaatca aaatgtgccg caatttcccg taaaaaagca
     2041 tctggatgag cctctacaaa ggctttcaat tcttctaaag ggatcttacg ctttttgacg
     2101 actcgctttt tccgctctaa gttcctttgt tcacgtcttt cttttcccac gtgaagagag
     2161 ttctgacgcc aacaccaaaa aactttggcc gcctcgacat gtctgtgccc tcctttgatg
     2221 gaatctaatg ctccttgttt aaaatcagta ttatatgcca tagctttatt agaccatgct
     2281 tattttaaac taagcaacta tatcaatgtt ttgttatgag aagacttact ttttttactg
     2341 aaattgaatt tttcctagcc tcaacatcat ataaccccaa aattcaatct gacctggttt
     2401 gaagagatgt tcgaagcaga taaggtttta ctaaaactaa aaaaaatgat ataatcaaac
     2461 tgattaaatg ttttaaaaat aaaggagaat ttgaatgtct taccaagaaa attaccagaa
     2521 atgggttgat tttgtggagc ttcctgacta ccttcgtcaa gatttggaaa atatggacga
     2581 aaaaactaag gaagatgcct tctatacaaa tcttgaattt ggtactgcag gtatgcgtgg
     2641 cttggttggt gctggtacaa accgtatcaa catctacgtt gttcgccaag ctactgaagg
     2701 attggctcgt ttgattgagt caaaaggtgg aaacgagaaa gaacgcggtg tagcaattgc
     2761 ctacgatagc cgtcacttct cacctgagtt tgcctttgaa tctgcggcag ttcttgctaa
     2821 acacggcatc aaatcttacg tatttgaaag ccttcgtccg actccagaac tatcatttgc
     2881 agttcgtcat ctcaactgtt tcgcaggtat catggtcaca gccagccaca accctgctcc
     2941 atttaacggt tacaaggttt acggtgaaga cggtggacaa atgcctccac acgatgcgga
     3001 cgctttgact acttatatcc gtgcaatcga aaacccattt gcagttgaag ttgctgatgt
     3061 ggaaactgaa aaagcttctg gcttgattga agttatcggc gaagctgttg acgtagaata
     3121 ccttaaagag gttaaggacg taaacatcaa cccagccttg attgaagaat ttggtaaaga
     3181 catgaagatt gtctacacac cacttcatgg tactggtgaa atgttggctc gtcgtgctct
     3241 tgcccaagca ggatttgact ctgttcaagt tgttgaagcg caagcaactg ctgacccaga
     3301 cttctcaact gtaacatctc caaacccaga aagccaagca gcctttgccc ttgctgaaga
     3361 acttggtcgt caagttggtg cagatgttct tgtcgcaact gacccagacg ctgaccgtgt
     3421 tggtgttgaa gttcttcaaa aagatggtag ctacctcaac ctttcaggta accaaatcgg
     3481 tgctatcatg gctaaataca tcttggaagc tcacaaaaac gctggaactc ttcctgaaaa
     3541 tgccgctctc tgcaaatcta tcgtttcaac tgacttggta acgaagattg ctgaaagcta
     3601 cggcgcaact atgttcaacg tcttgacagg tttcaaattt atcgctgaaa aaatccaaga
     3661 attcgaagaa aaacacaacc acacttacat gatgggattt gaagaaagct tcggttactt
     3721 gattaaacca tttgtacgtg ataaagatgc catccaagcc gttcttgtcg ttgctgaact
     3781 tgctgcctac taccgttctc gtggtttgac acttgctgac ggtatcgaag aaatctataa
     3841 agaatatggc tactacgcag aaaaaacaat ctctgttact ctttcaggtg tcgatggtgc
     3901 tgaacaaatc aaagcgatta tggctaaatt ccgcaacaat gctccaaaag aatggaacgc
     3961 aacagctatc actgtcgtag aagacttcaa ggcacaaact gctactgttg ctgacggtac
     4021 tgttacaaac ttgacaactc ctccaagtga tgtgttgaaa tacacacttg ctgacggttc
     4081 atggattgcc gttcgccctt caggtacaga accaaaaatc aagttctaca ttgcagttgt
     4141 aggagaaacc aacgaagaat cacaagctaa gattgctaac atcgaagcag aaatcaatgc
     4201 atttgtaaaa taaagaccta taaaagatga gaccaaccaa cctcatcttt tttcgtatca
     4261 aatctaagca attttagaaa ctttatggca tactagactt atcaatgaaa gcgaggtaat
     4321 ctcatggaac aatttttaga taacatcaaa gaccttgaag tcactacagt tgtgcgtgcg
     4381 caagaagctc ttgataaaaa agaaactgca accttcttta tcggtcgcaa aacttgccct
     4441 tactgccgta aatttgcagg tacattgtca ggtgtcgtag ctgaaaccaa agctcacatt
     4501 tacttcatca atagtgaaga accaagccaa ctcaatgatt tgcaagcatt ccgctcacgc
     4561 tatggaatcc caactgtacc aggttttgtt catattacag atggacaaat caacgtccgt
     4621 tgcgactctt caatgtcagc acaagaaatc aaagatttcg caggattgta aaaaatcagc
     4681 taacaagtct taaaatcaca aaaacgcata atgtaaggtg caaaaacctt gatattatgc
     4741 gttttattgt tcctaaaaca gttacatcag catttcatta cagaacattt taattttgga
     4801 agtcaaatca atttttaaca atgttttaga aatcacagtg ggctattcca tattaaatta
     4861 tccagattca atcgctatta tcgttttcct agattacaaa aaaactgcgt tttgctaatc
     4921 aaaacgtagt ctcagccact attttatctt actgtccttc ttttacttct ttggttgcta
     4981 catcttctcc aaaccatttt tggctgattt cttggaactt gccgtccttg taaagactag
     5041 aaaaagcttc atttatcttc ttaaccaagg ttgtatcttc cttacgggct ccaaccgcaa
     5101 aagcttctgt ttctagtcca actgtaaaga cattataatc gtttaaaaca ccttctgctt
     5161 ctaaataata gtttgcatag acacggtcaa tcaatagacc atcaattcga tcgtttttca
     5221 aatcaatcaa ggcttcatta aaggtttggt attgattcgc ttccttatta gcgacaatat
     5281 tcttcaaaat ttctggattt gcttcaaagt ccgcataacc agatgaacca gcttgagctc
     5341 ctaatgtctt tccagtcata tcctttgcag tcgtgatacc agatgatttc ttcgtaacca
     5401 atacctgctc attcttcata tatgagttac tgaaagccac cttttcacgg cgttcgtctg
     5461 tagcggaata gccattccaa atcagatcaa tcgttccttt tgtcaattca gcttctttca
     5521 aatcccaatc aatcggttgc caatttaccg tgattccgta tttttcaaaa acagctgtag
     5581 ctaaatcaat atcaaatcct gcataagaac catctttctg agcaaatccc attggaacaa
     5641 aagtactatc aaatccaata gtaatagact tgttagactg gtactttgac caattatctc
     5701 cactagtttc gctagaattt ttcccacaag ctactaagaa caaagcagtc atcagactga
     5761 ctaatacaag catccatttt ttcatccatt tttcctccta tttaggttct actttcaata
     5821 atacatctgc gatattttca gcaaactgca aatcatgggt aaccacaatc tgggtcatcc
     5881 caagttccct attttgcaag attagcttct ccacttccaa acgtaattct ggatccaggg
     5941 cagaagttgg ttcatcgtag ccaatgattt ctgggtcaat catcatagca cgcgccaaag
     6001 ccacccgctg cttttgccca ccagatagtg agaaaggata ggcctctgcg tgtcctccta
     6061 gtcctaactg ttccaagagt ccactcgcct tcttctcagc ctcttcctgc ttcattccca
     6121 tggtcttcac aggcgataag gtcaaattgt ccagaactga taaatgaggg aacagttgaa
     6181 aatcttggaa tacaaatccc agtagattgc gcttctgcaa ttcatccagc tctaaaggtt
     6241 gtccattata aaagatttgc cctgaatcaa tggtttcaag acctgcaagc atacgtaaaa
     6301 gagttgtctt acctccacca gaaggtccaa cgatagccag gatttgcttt tcaggaatac
     6361 ttagactgaa attagacagg atttgtttgt ctccaaagac tttattgata tttcgtaatt
     6421 ctaacatggc agcctcctat ctataataac tatacttctt ctcaactttt ttggaaataa
     6481 ttgtcacaat cccaatcaaa atcaaataaa tggctcctgc caagaacata ggaactagac
     6541 tagcatcgcg gttagcagct gttcgactag ccaagataag gtctgaaatt ccgagagcat
     6601 agaccaaaga agtatccttg accaaactca taacttcatt aaagacacta ggaagaacga
     6661 tcttggtcac ttggggcaag ataatatagc gcactctgtc aaaagggcta aacttcaaga
     6721 ccttggcggc ctcatactgt cctcttggaa tagtgtcaat tcccccacgg aaaatttctg
     6781 caaagtaagc tgcatagttg agaacaaagg caataatagc tgcaggaagg cggtctaaac
     6841 gaatcccaat acttgggagc acataataga taaaaatcag ttgcaagagt aagggggttc
     6901 ctcgcataac ccagatgtaa atgttaatca gataatggag gggcttccaa tggacttgca
     6961 aggcaaaggc aatcaaaacg cccaagggaa tcgaaaatag caagaccagt gcaaagacct
     7021 gtacagtcgt gctcgcacca ttcagtaaac tcggtaatat ctcaaataaa taagacatac
     7081 tgcacctcct aaaagtaatt gttcctatta tagcatgaat aaacaagatt accaagtatt
     7141 tttgtaaaaa gattctacca tatacaaata aaaaccgtag ctatcaaaag agataaacta
     7201 cagttctata tgtttaaaca ttcttacaat ctctcaaaca gttcttgcat ttgcacatca
     7261 tctggaacca gttttaagta agtgtgagca tggacttttg cttcttcaaa atgtcccaat
     7321 tcacgcaaga gatagatata gtgttccaga aattctggat tgtccttcaa atctcctatc
     7381 aactcttgat aatgctcata agcagtatcc aaatcgtcca tttcttgata agaacgagca
     7441 atcatccact tggtcaaaag attttctgac tcctcactct gcaagtctag aatatcctca
     7501 taacgctcct gctccagata aatagtggct aaacgaagca agatttcttc tgtatcctca
     7561 gcgtcttctt ttgcagtaag gagataattt tctgcaccac tagcatcatg caattcataa
     7621 gaaaattgtg aagcagctag caagaggcga gtttcaaagg gatttttctc taatccttgc
     7681 ttagcgatac gcagggcttc ttgaacttga tgttccttat gtaaagcctg actgtaccca
     7741 tactcatagc cttcaaagtc aggagaaatg gtatcaagct gcttaaagta gagggtggct
     7801 ttttgatatt cttcttgatc aaaataaaga ctggccaact caaaagctgt taagtcatcg
     7861 tattctaact ccagggcttt ttctaaaaac tcagtagccg tttcaaattt ccctaactga
     7921 gcataggcaa agccaattcg ttgataggtg gaaatgcccg tttgctcata aatcgagcga
     7981 ttatctaact gggcataggc ttgaatagcc gcttggtaat tttccaactc actatccaac
     8041 tctgccaaac ccaatatcaa gagagaatcc tctgagtagg tcaaggcctc caataatttc
     8101 tcacgtgcca catctgtcaa accttccagc tggtaaaggt ctgccttcag agccaaagac
     8161 gagacatacc agtcactgtc agcttggatt tcctcaagat aggtaaaggc ttcttctatt
     8221 tgaccatcct cgctagcaat tgcagctaga ttaagatgaa cctctggaaa atcctctaca
     8281 attttcaggt aaatttcctt ggcctgagga tagaaaccaa tcccttcaag ataagttgcc
     8341 aactcataca gaagatcact tgaatcattt tctaaagctt tggcgaaata atgctcagcc
     8401 ttagttaaat cttgctcctc caaagcctgt aacatctgtt gactattgtt cactcttgac
     8461 ttcctcaccc tctaattcat atagaccact gactacctta taccattcga aaatggctga
     8521 aatgacaacc ttagcagagg cataaaccgg aataccaagt aaaactcccc agataccaaa
     8581 catagatcct gaagttaaca aaacaaagag aacattaata gggtggatgt ttaattgact
     8641 tcccaaaatc aatggagaga caaaacggcc ttcaatagtt tgttctacga taaagacaat
     8701 cactactttc aaaagcatga ctggaccagc aatcaaaccc aatactagag caggaagcat
     8761 ggctagaaag ctaccaagat aagggaccag atttaaaata ccagcagtaa cccccagcgt
     8821 aaccgcatag cgtagaccaa taatcttgaa gaagatgata aacattactg ctacaataat
     8881 agccactgtc acttgccctc gaacatagtt ggacaactgt tgattcacat ctgataaaac
     8941 ttgtccaaca ggttccttca attttcttgg aatgaattgg gtcaaatagt tacgcaagcc
     9001 tttcccatca cgcaagagat aaaagagcat gaaaggaacg ataatcaagg caacaatcac
     9061 ttgagaagct ccgctaataa aggcactcac ccagttgact gcctgagatg aaaccttact
     9121 tgccaaaact gtagcctggc tagaaaaatt ggtcaaaact tgctctaatt gaggtctgaa
     9181 atcatctggc aggtgctggg ctaccaatcc attaacaatc ctatctatat cttctaagta
     9241 aacaggaacg tttcttgcaa aggtcaaaac ctgacgttgc agatttggaa tggcgactgc
     9301 caagccccaa atgataaaga gagcgatgat aacaaagaca atagtgatag ctataacacg
     9361 attaacctta tgcttctcca tccaatcaac aataggattc aacaaataat ataacaaacc
     9421 agacaaaatg actggcaaca tcacaactgc taaaaagtct aaaacaggtg aaaatagaaa
     9481 actaatctta cttaaaataa aaagattcag tcccaataat aaggttacta aaaataccgt
     9541 aattgccttg ttatctaaaa accacttgaa aaaccaagat aggctaaaat gtttctcttt
     9601 ttgctccata aatacttcct ttctattgtt ctctcattat accatttttg aaacaaaata
     9661 actctttttt aaagtgctta catctaattg gatatcttta atttacttgt ttttgtgata
     9721 taatagtctt atctttacac agaggtatag taatgaaaga aactgtttat tttggaactt
     9781 atacacgtcg tacttctcaa gggatttaca aggcagactt tgatacagaa actggtcagc
     9841 tttcaaatct agaacttttt gcagctgagc caagtccaac ctaccttgcc tttgaccagc
     9901 accaacattt atacactgtt ggtagccaag acgataaggg gggaattgca gcctatcaaa
     9961 ctgacgggac tgtgttaaat catgttgttg aagaaggagc tccccactgt tatgttgctg
    10021 tcgatgaaaa gcgtgatttg gtttacgcag ccaactatca caagggacaa gtccttgttt
    10081 ataaacgcca ggaagatggt agtcttctac ttagtgatat ggatcaacac agtggccaag
    10141 gtccacatga aaatcaagct tccccccatg ttcactatac agatttaaca cctgaccact
    10201 atctagtgac ctgcgacttg ggaactgacc aagtcatcac ctatgacctc gatcaagaag
    10261 gaaaattatc taagctctat acctatcaca gcaagccagg agcaggctca cgccatatca
    10321 ttttccataa ccactataaa atcgcttatc tcatttgtga actcaatagt actatcgaag
    10381 ttttaatcta cgatggcgtt ggcgaatttg aacgtatgca ggtcatttca actttaccgg
    10441 aagcttacga aggctttaat ggaaccgctg ctattcatct ctctaaagac ggtaaatacc
    10501 tctacgcttc taaccgtggc catgattcta tcgcagtata taccatcctt gcggacggta
    10561 gcttagagtt attagaaatc gttccaacgc atggtcagac tccacgtgat tttgatttga
    10621 cacccgacca aaaatttctc attgttgtcc atcaagactc tgacaatgca actgtcttta
    10681 aacgtaattg tgacaatggt cgtctagcag aactctccaa cgacttccat gttcccgaag
    10741 cagtctgcat ccgttttgct ccttaaaaca ccataaaaaa tgaacttggt attttcaagt
    10801 tcattttttc ttatagtcta tttccgacat taatacggtt aatagcacgt tgcaaagcaa
    10861 tcttagcacg acgttcttgg tcaatcaaat gtttgtcttg tgcttcttca attgcacgtt
    10921 ctgcacgaag tttggcacgt tctgcacgac tgatatcgat atcacgagca cgttctgcag
    10981 agtcagcgac gattgtgatc atatcattgg caatttcaat aacaccaccg tttactgcaa
    11041 tccagttcac ttgatcttta tcatcgatac gttttacctt tacttcatca actgctaaaa
    11101 ccgcaatcat attttcatgt cgtggcaaga tccccatctc accatccaga gttcgaaccg
    11161 atacatagct ggcatggtga tcatagacga gaccatctgg tgtcacgatc tggacagtta
    11221 actgagccat agttcacctc ttaaaatccc attttttcag cttttgcaat cacatcttcg
    11281 atagaaccta caccacggaa ggcatcttct ggcaagtggt cgtatttacc atcaaggatt
    11341 tccttaaagc cacgtacagt ttcagcaact ggaacataag aacctggctg accagtaaat
    11401 tgttccgcaa cattgaagtt ttgtgacaag aagaactgga tacgacgggc gcgagcaacc
    11461 aaggtctttt cttcatcaga aagttcatcc ataccaagga tagcaatgat atcttgcaat
    11521 tcatggtaac gttgaaggac acgttttact tcagcagcaa ctgcatagtg ctcttctcca
    11581 acgatttcag gtgccaaggc acgtgagctt gaagcaagtg ggtcaacggc tgggtagata
    11641 cccaattgta ccaacttacg ttccaagttt gttgttgaat ccaagtgagc gaaggctgtt
    11701 gctggcgctg ggtcagtata gtcatccgct ggcacataga tagcctggat agaggttaca
    11761 gaacccttct tggttgatgt gatacgttct tgcaattgac ccatttccgt agcaagtgtt
    11821 ggttggtaac caacggctga tggcatacga cccaaaaggg cagatacttc tgaaccagcc
    11881 tgagtgaaac ggaagatatt atcgataaag agaagcacgt cttggccttc cacatcacgg
    11941 aagtattcag cgattgtcaa accagtaagg gcaacacgca tacgtgctcc tggtggctca
    12001 ttcatctgac caaagaccat ggctgttttc tcgataacgc ctgattcttt catttcccag
    12061 taaaggtcat tcccctcacg agtacgttcc ccaacaccag caaatactga aataccaccg
    12121 tgctcttggg caatgttgtg aatcaattct tggattaaga cagttttacc aactccggca
    12181 ccaccgaaaa gtccaacttt accaccttta aggtaagggg caagaaggtc aataaccttg
    12241 atccctgttt caaggatttc agaagaggta gacaactcat caaaagttgg agctttttta
    12301 tgaattggct gacgctctgc gtcttctgta aaaggagctt ccaagtcaat ggtatctccc
    12361 aaaacgttga agacacgtcc caaagtttct ttacctactg gtacagagat tggacgacct
    12421 gtgtccaata cttccattcc acgagtcaac ccatctgttg attccatggc gatagtacga
    12481 accataccat ctcctaactc caaggctact tcaaggacga tttttgtttt tctttcgtca
    12541 tttttgtaga cgacaagtgc attgttaatc tcaggaagtt tttcccctgc tgcaaacaaa
    12601 acgtctacaa cgggaccgat aacctgagca attttacctg aactcatctc cttctcctat
    12661 tctatataag atactgtcgg ttcctagctc aactaggtcc taagttcatt ttcatacgag
    12721 ctggactaga gcctattcta aggcactagc acctgctacg atttctgtaa tttcttgtgt
    12781 aatcgccgcc tgtctggcac ggttatactg aattgtcaaa tcattgatga ctttcttagc
    12841 attatctgtc gctgtttgca tggctgtcat acccgcagca ttctcagctg tcttggcatc
    12901 tataatggca ccgtaaatca tactttctgc aaactgaggc aacaactgct ccagaatttc
    12961 ttctcggctg gtttccaatt caaaagtcaa gctgtactct tcatccgctt catttggatc
    13021 caagtcaaca atcggaagca tttgttccac acgcatttga ctggttagcg tattgacatg
    13081 gtggttgtag caaacataaa gctcatcaaa gagttcattt tggtacattt caacagtttt
    13141 tgaaataatc ttacgaactt gatcaaagct aggttggtct gccaagccac gtaattcata
    13201 aagtggttga ataccgcgag ccttaaagaa atcagctccc atcccaccga tacagatcat
    13261 ttcaaaacct ttaccgtctg ggtggtattc ttctttcaac tccataacag ctttcaaaat
    13321 agaggaatta taacctccaa ccaaaccgcg gtctgaagtg ataacgatat agcctgtctt
    13381 cttcacagaa cggctaatca acatcggatt agttgaagca ccagctccat taccatgaag
    13441 gatatctgtc aaaagtttac gcactttctg agcgtaaact tggaagttgc gagcagcttc
    13501 ttcagagcga cctagcttag cagccgatac catttgcatg gcattagtga tttgactcgt
    13561 attttttgtt gaggcgattt ttgttttaat atcatttaga gatactgcca tctgacacct
    13621 ctattcttat tggaagctag attgattgag aaactctgta atcgcagcat ccaagactgc
    13681 ttcttctggc aagtcttttg tatcacgaat ggtttccaaa atctctggat gttgagcatc
    13741 aaagaaggca tggaactctt cctcgaaacg aacaatatca tctactggaa cagtatccaa
    13801 gaaaccatgt atcaaagcat aaagaatggt tacttgtttc tcaacaggta atggtttgtg
    13861 aacaggttgt ttcaagacct caacggtacg acgtccacgg ttcaacttag cctgtgttgc
    13921 tgcgtccaag tcagaaccaa acttagtaaa ggcttccaac tcacggtatg aagcaaggtc
    13981 gatacgaagt gtaccagcaa ccttcttcat ggctttgatt tgtgcagaac cacctacacg
    14041 agatacagat gaacccgcat cgatggctgg acgaatacct gcattgaaga ggccatcgcc
    14101 aaggaagatt tgtccatcag tgatagaaat cacgttggtt gcgatatagg ctgagatatc
    14161 tcctgcttgt gtctcgataa atggtagggc tgtaattgat ccaccaccaa gttcatcaga
    14221 aactttagct gagcgctcaa gcaaacggct gtggagatag aaaacatccc ctgggaaggc
    14281 ttcacgacct ggaggacgac gaagcaagag cgacagttca cgataagcta ccgcttgttt
    14341 tgatagatca tcgtatacaa tcaaaacatg cttaccttga tacataaatt cttccgccat
    14401 agcgacccca gtataaggag ctaggaagag caatggagat ggttgtgaag cagaggctgt
    14461 cacaacgatt gtgtagtcca aggcaccgta ctgacgaagt gtttctactt gcgtacgaac
    14521 tgttgattct ttttgtccaa tcgcgacgta gatacagatc atatcttgat ctttttggtt
    14581 caagattgta tcaatcgcaa tggttgtttt ccctgtctga cggtcaccga taatcaactc
    14641 acgttgacca cgaccaatcg gtacaagggc gtcaatagct ttcaaaccag tttgcaatgg
    14701 ttctgaaaca gacttacgtt gcataacacc aggagctggt gcttctactg gacgagtttt
    14761 atcagtgtgg atttctccaa gaccgtcaac tggacgacca agcggatcca caacacgacc
    14821 aatcagactt tcacctacag ggacttccat gattttccct gtacggcgga ttgtatcgcc
    14881 ttcacggata tctgtaaagt cacctaggat gataatacca acgtctgttg actccaagtt
    14941 ttgagccata ccataagagc cgttttcaaa attcaacaac tctccactca tgacattttc
    15001 aaggccgtga gcacgcgcga taccgtcccc gatataggtt acaacacctg tttcagtcac
    15061 atcaaaattg ggtttgaaat tttcaatttg ttgcttaatt aaagcgctga tttcttgtgc
    15121 gttaattgcc aaaagaacac cactttctat ttcaaatttt ctttaacaac tttaagttgt
    15181 tgtttaatac tcacatcaat tgtcttgtga ttggcaaaaa tgacaaaacc accaatgaga
    15241 ctttcatcga tttgttcttt tacactcctt actttcagag acattttttt ctcaatcaaa
    15301 gggagcaaac gagtcttctg ttcatcagtt agaggatgag cagacgtaat cgtcacttca
    15361 aatcgatttg tttctttttc aagtcggttc aagcaatcta caagcacatc ataaaaaaga
    15421 tttgctctgt gattgtaggc cagaacctgg ataaagtttt gtaataaagg cgacacagaa
    15481 tcttggaaaa aagcaattgt tttttcctta tccgactcgt ctactgccac ttgttttaaa
    15541 aaagaaggca gacctgtttt ttcaacaact tgcttgattt gagtcaagtc tgaaaagata
    15601 cggtcttctt ctcctttttc aagtaccaat tggacaaaag gcatgctgta tttttcaatt
    15661 acctttactg ttttcttgtc cattaagctt ctcctagctg atcgatatac tgatcaatga
    15721 gtgctttatg ggcatgactg tcaaggtttt gtgagatgat tttaccagct aagctgatgg
    15781 tcagatctgc gacctcaccc ttaacactct gtaaagcttc tactttattt tgagcaattt
    15841 cttgattggc tttttctttt aagtgtcctg cttctagttt agcatctgct aagatattag
    15901 ccttactttg ctcagctgtt tcctttgcat tttcaatgat tgtcttagct tctttacggc
    15961 taccagccaa ttcatcttcg cgtttttgag ccaatacttc tgctttttga cgggcttctt
    16021 cagctctgtc aatatctgaa gcaatttttt cagctctttc ttcgaaaatg cctgtaatat
    16081 tagaccatgc aaatttttta atcaagacta gcaaaagaat aaaagagcca gtgattaaaa
    16141 taaaattacc aattaattca cctactgtta cgtgcatcag ttactccttt ctattcctct
    16201 tcaatattaa tcttattccc taaatacaca gatgtcaaaa gagtaaaaac ataagcttgg
    16261 atgcaggaaa taaagacaga aaatgcagtc caagccaaat tagctccaaa ggctactgga
    16321 taccaataaa tagcttggtg ggaaagaaga agtaacaaac tcgtcatgac ctctcctgca
    16381 aagatattcc caaaaatccg caaagccaaa gataagaagt ttgtaaattc ttccaagata
    16441 ttcatcggta tgacaaaaac aggactcata aaagatttta tacttttttt aaatccacga
    16501 cgacgaacgc tttctatatg tgtcaacaaa atgacaagaa aagataaggt taagtcatac
    16561 tgtaaattag cggttggcga actccaccag ttagtcccat cgatcgtttg aagctttgtc
    16621 attaagccaa ggttattggc aatcaccatg aaaaggaata aacaaaggaa aaagagtgaa
    16681 taatctttca tgtagcgcga accaatgtta ggttctgtaa atccaataac aaagtcatag
    16741 acatactcaa gtacattttg ctttcctttg ggtttcaagg tcatattgcg gcttgcccaa
    16801 taaataaaga caaaaataac tcccacaatc aacaaagtca tggctaacat agtcagattg
    16861 aagataacag gaccaataga gatgattgga ttaatacttt cttccatcta aaatcctccc
    16921 ttttcttctc gttccatgta tttatttgat aataaatgag aagacaagag ttacaaagaa
    16981 agttccttca ataaaggcaa cacctaaaaa catcaaacta cgaaactcag aaagcatatc
    17041 tggttggcgt gctactgatt taaacagtcc attcatcaat aaaccttcac cgacagatac
    17101 gcccatacag gcaatacata agcctaaaaa tgttaaattc ataacaaatt ctcctttaaa
    17161 ataaaattta cttacttagt gtagtcctaa aatttaaatt tgtcaacttt taaccgctat
    17221 tggaagcgtt taataaaaat tatttccatt ttgctaaatt tcaagttcaa gttagccatc
    17281 ca
//
LOCUS       DAVAZT010000048        16998 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVAZT010000048 DAVAZT010000000
VERSION     DAVAZT010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16998
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.048"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(156..2249)
                     /locus_tag="VQT45_001594"
                     /pseudo
     CDS             complement(156..2249)
                     /locus_tag="VQT45_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397758.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
     gene            complement(2242..2790)
                     /locus_tag="VQT45_001595"
                     /pseudo
     CDS             complement(2242..2790)
                     /locus_tag="VQT45_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000059560.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2871..2933)
                     /locus_tag="VQT45_001596"
     CDS             complement(2871..2933)
                     /locus_tag="VQT45_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HET2359893.1"
                     /translation="MKKISKFLPILVLVMDIIII"
     gene            complement(3102..4090)
                     /locus_tag="VQT45_001597"
                     /pseudo
     CDS             complement(3102..4090)
                     /locus_tag="VQT45_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050775.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(4039..5166)
                     /locus_tag="VQT45_001598"
                     /pseudo
     CDS             complement(4039..5166)
                     /locus_tag="VQT45_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423473.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
     gene            complement(5329..6213)
                     /locus_tag="VQT45_001599"
     CDS             complement(5329..6213)
                     /locus_tag="VQT45_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HET2359894.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            complement(6325..7179)
                     /locus_tag="VQT45_001600"
     CDS             complement(6325..7179)
                     /locus_tag="VQT45_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HET2359895.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNLTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCNIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(7237..7995)
                     /locus_tag="VQT45_001601"
     CDS             complement(7237..7995)
                     /locus_tag="VQT45_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET2359896.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYALS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVVF"
     gene            complement(8057..8245)
                     /locus_tag="VQT45_001602"
     CDS             complement(8057..8245)
                     /locus_tag="VQT45_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HET2359897.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(8567..9133)
                     /locus_tag="VQT45_001603"
     CDS             complement(8567..9133)
                     /locus_tag="VQT45_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359898.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKTYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(9401..11080)
                     /locus_tag="VQT45_001604"
     CDS             complement(9401..11080)
                     /locus_tag="VQT45_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HET2359899.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGRIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCNHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKVDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            complement(11172..11333)
                     /locus_tag="VQT45_001605"
     CDS             complement(11172..11333)
                     /locus_tag="VQT45_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359900.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            complement(12017..12331)
                     /locus_tag="VQT45_001606"
     CDS             complement(12017..12331)
                     /locus_tag="VQT45_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359901.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            complement(12297..12686)
                     /locus_tag="VQT45_001607"
     CDS             complement(12297..12686)
                     /locus_tag="VQT45_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2359902.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYRDR"
     gene            complement(13074..13868)
                     /locus_tag="VQT45_001608"
     CDS             complement(13074..13868)
                     /locus_tag="VQT45_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2359903.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
     gene            complement(13868..14875)
                     /locus_tag="VQT45_001609"
     CDS             complement(13868..14875)
                     /locus_tag="VQT45_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET2359904.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(14875..15882)
                     /locus_tag="VQT45_001610"
     CDS             complement(14875..15882)
                     /locus_tag="VQT45_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET2359905.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLATFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(15872..16897)
                     /locus_tag="VQT45_001611"
     CDS             complement(15872..16897)
                     /locus_tag="VQT45_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HET2359906.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVISDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
BASE COUNT         5326 a         3215 c         2286 g         6171 t
ORIGIN      
        1 cctaaagaaa taccatattc aactggaaaa tctaaaaaaa ttgcaaatac tattccaatc
       61 atcaccccta gtgaggctgc tgttgaaatt acatattcat ttactttctt cattttcttt
      121 acacctcatt tcctttttgt atataagctg tagtactatc caccaagatc cattaagtac
      181 ttatgatttc ctgactcaac aatcttacca cctttcatta caaaaataat atccgcatcc
      241 ttaatcgttg acaatctatg agctataatt atttgagtac aatcctgact ttgtatatac
      301 tttgttattc tttcctcatt aatagtgtct aatgcactag ttgcttcatc taaaattaca
      361 atactaggat tatttattaa tgcacgtgcc agtgctatcc gttgcctttg cccacctgaa
      421 atatttgacc ccatctctga gatgatagta ttaaatttca tcggcatagc catgatttca
      481 tcatagattt gaactgcttt acaaacttcc tctatctttt gtgaagtaac ttcgttcttt
      541 aaagttatat tatcaagaat acttcggttc aataaaaatg aatcctgtgg aactactcct
      601 aaattttgac ttaatatttt tttatctatt tgattaatat ttacaccatc aaataaaatt
      661 tttcctgtat caatcttata taatcctgat agtatttttg ataacgtact ttttcctgac
      721 cccgattgac cgactagtgc aattctctgt cctggctcaa tagtcaaatt taaattttct
      781 attacaggag ctgagtcttt ggaataagag aaagataggt ccttaatatc tattctacct
      841 tctaaagaac actttttaag accattttca acattctctt cattttcaag ccagatatca
      901 tttactctat ttaagtatcc tgctgccaaa atatactacg tataagcatt aaatattgag
      961 atttctgaac taaataaaat tgatgccatc gtttgaaatg cgacaacctc acccaataaa
     1021 atttttccat ttaaaacatt atcaagtcca aaaatcaata taattatagg agcgaacaat
     1081 tgaaatacat tagtagctga attgtataaa atatgcacaa tacttcgttt tttatacttt
     1141 gtcaatacgt tttttaaata cttagaccag ttttcatata tttcatcttc taatcccgat
     1201 atttttattg aagaaatagt atttaatgct tctgtttcta ctgagtaaat caatgattgt
     1261 tcttgtaatt ctctattaac cgtatcatac attatttttc tagtactaaa cagaaacaaa
     1321 aaattgatta aactcaatat aagagctata attgataatg tttttgaact aagaaacata
     1381 tatattacaa cacttagaat agtcccgata tctactactc ccccaacaac ttggttagta
     1441 aatagctccc taaaaccact aagactagaa attctgtata aaatatctcc ttttgccctg
     1501 agttcaaaaa aactatatgg tagtttaagc aaatgcttaa atgtaaaact ttcaatatct
     1561 ctactaaaaa atatattaga aaatagaatt cccatactcc tagccaagat agaaataagg
     1621 tacaaacaaa gtagagaaaa taaaattaaa aacgaggttt gaaaagaaaa tgtattccct
     1681 aatgcagaat taataaactt tgaagtcatt actggtacgg aaagtattat taagtaactt
     1741 attattgaaa atagtaacgt caaaatcaat cgacctttta cctttgaaaa actagagaat
     1801 actcttatcc atggagaagg aaactgcgac ttcaaagatt gataattttc gttaggaaat
     1861 gatagcagta ctatattact aaaatgtttt gaaaactcct taaactcata atttatatat
     1921 cctttagaag gatccattat atagacctta ttctttttta ctttgtaaat aactacataa
     1981 tgttgattat cccagaatgc tattaatggt aacggaagtt cactaatttt atttacatct
     2041 ttaacttgat atgagccagt atcaaaattt cgtttattca ataactgttt caagtcacct
     2101 atactataac catctctccc tttttctata tcacgtctta aatctagtaa tgtctctttg
     2161 cttttataga aatgtagtat ggacaagcag caacataaac cacattctat ttgagacatt
     2221 tgctcaatat taggtacttt tctagtcatc atgtcctctt aactccagta ataaaacatt
     2281 aagtaatcta tcatcttgtt ttcgagatat ttcatagaca actccagata ctcctagcat
     2341 aaaagaaaat gtattcatag tattcaaatc cgtacttaat tctggtttga taacctgaga
     2401 aacgacatta tcaaaataaa aatctataga ttcttttatt aataggtttt cttcatcttt
     2461 caatattgca tcaagacaac tgatagtacc tacagaaccg tgacataaat tcaattctct
     2521 tattttttct acattagtta atacattttc aattattgat aaatcattat tcccaatatt
     2581 agttttatcg aaaatttctt ttctagctaa taaaatgccc ggagctccat aacaccaaaa
     2641 attaggaaag gaatcattat gatttcttca tatgtctttc caatttttta atatattatt
     2701 gaaacattta tcttctttat atagtaattc ctctatacat tttaatatat ctgtactagg
     2761 attaatttca taataatatg ataattacat tgctactcca gaataatcgt gtgctaaacc
     2821 tgttactgtt atattatcta attgtgaaat acaataatta atacactttt ttaaatgatg
     2881 ataatatcca tcaccaaaac caaaatcggt aaaaattttg aaattttctt catacttgga
     2941 cttcctttcc gtttttattt attgtacaat aaataaaaac ggatttaatt tttgttggga
     3001 aaatgggaaa ttatgaaatc aaaacttggc atcacactta gaaaagttcg taaaggaaaa
     3061 caaattagtc tatgctctgt agcagatgaa catctttcaa aatcacaaat atctcgtttt
     3121 gaacgtgggg agtcagagat atcttgtatt cgactaatca atattttaga caaattacat
     3181 attactttgt aggggagttt ttggctatcg ttgctcaatt gtctgattaa ggtcctaccc
     3241 ttgatgaaac aattattatc catgttttct ttattataga caaagtaaga agacgtttct
     3301 cgaatgtaga ctttatattt tttatgattt tcttcttcca taatatccaa ttgatagttg
     3361 ggaatgaaaa taagaccgct ctgtttgaca ccgaaagaca ccttgatata gacgccctta
     3421 tcaactagct tctctatttg gttctctgca agttccactt caaattcacg aacggtatct
     3481 catttttcct taaatgtctt aaaggcttcc tcaatctctt cagtggatac tttatcctta
     3541 tctcgttctt cttggaaagc atggtactgt tcctgtaaat tctctaatcc ttctgaagca
     3601 acgacttcct tatttttaaa ataatcttga aaaaatttga catcatataa tttcttatca
     3661 cttatttttt gatgacccaa acttatcttt tgattatttt cttccaggat aaaagttaca
     3721 ttttttgttt taagtcaatg gttagattca attcttttgc ttttgttatt aaatcttcta
     3781 aagaattgac acggtttaac aaaaattcta aacgactttc aatctcttgc ttagcaaaat
     3841 gcgttctaaa aaattcttca tcatatagat ctcgtttgct gagttggcgc cctcgaattg
     3901 gttttatcat cgttctatct gtcatcaaaa aacggctatg cttttgacta aaatcaatct
     3961 gaacatgcaa ctgctttgct ttctctaaaa aatcatcaaa cgatttagat tgctgaagca
     4021 aaaaataaag acgttgtttc aattcaaatt tatgactaga ttccttatat tttttataat
     4081 ctcgaaaaga tcaggatttt tagctaaaac tgccttacga aaatccttcc agaactgatg
     4141 gtcaatctca ttagccacat ccaaacgcca agcatcgata ttaaactctt caatccaata
     4201 agtcgcaacc tttaaaagat aattcttgac ctctggattg gctgtattta gcttaggcat
     4261 atagtcctcg aaaccaaaaa catgataggg taagtctctc ttattaacta gcttttcagt
     4321 tgtcaatggg aattgttgaa tatggaacca atccttataa gcagactgtt caccattttt
     4381 gacgacattt tttcattgaa gagattgcga accaatatga ttaaataccg catccagcat
     4441 gactttcatg ccacgatgat gcgcttgatc caccagttcc cgaaaggtct ccttgtctcc
     4501 aaaataacgg tcaatttcaa agtaatctgt cgtattgtac ttgtgattac ttgtagattc
     4561 aaagatggga caaagatata gtccagtaat acccaagtct tgcaagtaat tcatatgatc
     4621 aataatcccc tgtaaatcac caccaaagaa atcatcgctc ttaggtgtga cagatgaatc
     4681 ccagtctaaa gtcccttctg ggtttaatag agcattgcca ttggcaaatc tttcaggaaa
     4741 tatctgatac cataccgtat ttgaaaccca gtcaggaacc ttgcaggcat caatctcatg
     4801 aagataaggc aacttaaatc cattcccaat tgcatgaaga ttttctagag aattttccac
     4861 acacccttta tcgccataca aaatattttg accttctgta tctctgagct caaagagata
     4921 ctggatacgt gcaaagtcaa ctgacacttc aacctgccaa tggtcaaata aggtaccaga
     4981 agttatcttg accatttctt ttgtatcctg ataaaactct tccataaaga taaaagggtc
     5041 cccatagtgc aagttgatgc tttcaatgtc ccctttctta gttcgaattc gaatatggag
     5101 tttcttatcc ttataaagat aggcatactc cgactcaggc ctatggtaaa tagcactcaa
     5161 ttccatcaat ttgtctccta aagtattcat tcaaatttta cgcaaacgtt ttcaaactca
     5221 ataaatccag tatactattt ttgtaaacta tttgcaagga atgtccgttg ttaaaggaac
     5281 tatcttttaa agtatacaaa aagccttaaa aaaggctttc tctatatact aatcctcttt
     5341 cggttttgaa aatacttcta ctcgctgagc taggactttg atttctacag gtaggttatc
     5401 tgatttatct ccgtcaacat ctgactccaa ttcactatct gaagagattt taatattacg
     5461 cgctttgata tactcgatat tatcatttgc gacaacatcc ccttttaata aatcaggaat
     5521 gacggataat ttggagaata tagaggcatc tttcagaatc aaaatgttgg catagccgtc
     5581 cttgttttct tcaaagattt tcttatcagc gaagtaattt gtcaaaagga ccaaaacatg
     5641 gctagcttca ccaacataat ttccattttc tgtctcaacc ttaatgttaa agacctgatc
     5701 tgtcatgaca gacttcatgg tatttacagc ataggttaaa ataccgaatt ttgttttgtc
     5761 ctctatttca acattgtgaa tcgcctcagg cagagaaccg atactaaaga tataaccaaa
     5821 atagttgtca tttgctttac cgatatcaat cttattggtt aaatcaaaat ccagttcgtc
     5881 aattgcgcca tcgatgtctt gattgatttc caaaagtttt gtaatgaggt tacccgtacc
     5941 gcctgggata atccctaact taggaatgta gtctctctca tcaatacctg aaatgacttc
     6001 attgacagtt ccatctccac caaacacaac cactgcatca tactgctcac gagaagcttc
     6061 ttcagcaaaa tgtgttgcat ccagcgcttt ttcggtaatt ttggtttcaa catattcaaa
     6121 gtattctttt gctttattct ccagcttttc tttgtaatcc aaagccttct cgccaccaga
     6181 agtagggttg ataattacca ttgctttttt cattgatttt atccttaatt ttaaacagaa
     6241 atgtttacat ttcgtcgtat gcaagtaaat gtaatcctat tatacaatga aaatacagaa
     6301 aagagaaatc tgacgtactg gagattaata cgcttttatt ctattttccc atcgcctaac
     6361 tacatccttt aagggttcat ccaagtaaga ataggcctta tccttgatcc aatcaggaat
     6421 accgtaagct gcctctgcta tgttacaagt gattgctgcg agagtatcac tgtcgccacc
     6481 aagtgagatg gcatttctta tcgcatcttc gaagtctcta ctttcaagaa aggcgataat
     6541 ggcttgaggg acagtttcct gacatgtttc gttaaaacga tagttaggac ggatttcatc
     6601 taaagtttga gatagattgt aatcgtattc tttttctata taatccttaa ttcgtctttt
     6661 acactctgta agattgtcgt taattgattg ctcgtactct ctacaataac caccaaagta
     6721 aaaacgacat agaaagatag catcagctgt agccatagcg cctttgacac cttctggatg
     6781 attatgagtt acctctgcag aaagactcgt aagtcctcta gatgatggcc atataccagt
     6841 tttcgcataa aaaccacagt ccatgatcca agcacatgga gaaatacgca tagctgatcc
     6901 attcccaaag ctattataag gctcacggtt atcgctgttt agccatgcat taaaccgagc
     6961 accgtaatca gcattcggat acattctgcc atatttcttc atcgcgtcaa tgaaatcgtc
     7021 tttttgtcca ccattcataa ttgcttctgc aacagcacag gtcataaccg tgtcatctgt
     7081 aaaaaagcag tccttccgaa ataaaggaaa gtcctttgtt ttgatattgt tccattcgta
     7141 aacagaaccg acaatatctc caataattgc tccaagcatc agattcctcc ttgttcattt
     7201 tgatgctttt tatattggtt atataccata tttattttag aaaacaacat cctgttggat
     7261 tttaaaaatt tcattttttt caaaataggg ttttaccatt tctttccacc tagctctatg
     7321 aaaattgatt gattttaaag gagatagggc ataatttccc aatgcataac catcatttac
     7381 ttcaacaaca agtgttctgc catcgcgagt aacaccgata tctagtccat aagctattgg
     7441 cgcatctttc caacatgata tcgcttcatc aattacactt gcatcaaatt gtgcatgata
     7501 atcacctgta tagggtcgaa catctaatac gcgaccatct aacacaaaac aacgccattc
     7561 agctatgaat tctacaacct cactaatcca tataggatag tcgaaaggta gaccaatacc
     7621 tattaaatca tgggttccat taacaactct tccagtaaag acttttgaac cagctttagg
     7681 cttaataaat tttccccaat tatcaggtat attcacaatc tctcctaaaa taccagcata
     7741 aatctttcga ccataaaact ctttaagctc aataggatag tcataaaccg gaacgtttaa
     7801 gcccatcatt tttagtaatg ctctagtctc cattatataa tctacaacta tatcttcact
     7861 tgttaactct tttatttcag aaaaagattg atataaaata acttcttctc cttgtaagta
     7921 ggcacctact tgagcattgt atttattaat tgaaacctca cttggtaatt tactttgtct
     7981 aatataaaca accatttcat cactcctata tcactagtgt tacactgatt tgtaaaaaat
     8041 aatagcaatt ttgctcttat ttttttgagt aaatagctcc cataatatca tcgaaataat
     8101 caacggtatt taggagtaat tcaataacct gggactttgt tagtcgcatt ccccttctat
     8161 ctctagcatc ttctactaaa ttttcaagtt tctctagatt tttatcatcc aagctaatca
     8221 ttattctatt tttatcggtt gccattttca tcacctcaag ttaattctat cacaggtgta
     8281 acacttgtgt caactggctt ttataataca ttagtttaaa agtggagagg atttttaaca
     8341 cagtaacttt aaatctttgg tattaaaaaa ttttcacaat atttatagaa ataaaatctg
     8401 tctcaaatca gttatcaaat ctagtataaa ttatgagcgg ctactctaat actttccctc
     8461 taaacaagaa aaagacttac actcaaggat tttcttcccc cccttcgtta taacgttttg
     8521 actcttttac tagcaaaggt atatactcac aaggaacttt ggttgactat tgaatctctc
     8581 caacttcttc tttaacatat ccttctacat cttcaatctc tacaaacatt gggtctaagt
     8641 gacacaagaa atgccaaact tcgatccctt tttttctgta aagaatcgct tcaccgtctt
     8701 cacttccgaa aaagcttctg tcgatttcat atccgcggct ttctaagaag tcttttgctt
     8761 tacgatagtt cgtttctctt gtttcgacat aggttttaac ttcatggttg ttaacgacat
     8821 atgcatcaat ttttgaatat ccttcgatca ctctatcatt tttgagggat aaatttgaaa
     8881 tctctttcca aataatgttt acattttcct caggatcgaa cataaattta gataaaggaa
     8941 caatatttcc gttaaaaata atttccatat aatccggtat gtttttagga ttaaaatact
     9001 ccacttcaaa accatcttct gtttccagag tgtatcccgg gatttgagct acaaaggctt
     9061 tcccatcttc tatggaatca aatgctacta aatctttaga ataatcattt tggtacaatt
     9121 ccaatataac catcgataat ctctccattt tcattatcag gctaatgtaa ataagcacgt
     9181 cacctgacca attcaggctc tctgtatcat ctcatcatat ttcctactta ctttacgagt
     9241 cctataccca gaacacacct tatcgacctt cggtctcacc tcgttgcatt ggctgaacat
     9301 ctacttttac ttcgctgatg cttcaactcg tacaagcagt gataccgcct cagcgtgatg
     9361 cgtcagtggg actcaaaagg ttcggggaac cttttgagga ttaactacgt ttctctaata
     9421 aacttacaca ttcaacttgt tcatcattgt ccaaacctat gttgagattt tcttctataa
     9481 ttggtagctt aaaagtaatg gattttagcc attgtccgtt agattgtttt tcttcataaa
     9541 cttgaatttc agaaatcaaa gctgaaatta actgcctacg ctctacatca ttcatgactt
     9601 tatagagctt atcaaaatag atcagaacct tatatatgtt atctcctgta agcttttcag
     9661 cttcaatagt ctgtttcttt gctttcgcat caattagtga tgattctaat tcatctactt
     9721 tgtcatacat acgatatagt ctatcatcta aatcctgttt ccttctctta taatgcttat
     9781 cttcaacatc taaattatct atttcctcaa ttagcttaaa ctttgtagaa tgactctttc
     9841 tcaattcctt ttggtaatta tctatttctt tttctatttc agaggtatcc accttcatgt
     9901 tgattttttc ttgcatcata gaagcaaatt tcggattact tactatcttg acaatcacct
     9961 ctgcaacagc atcatctaac aattcttctc taatttgctt actgaatgta cacttatgac
    10021 ctcttatcat ctgcctatgg ttacaaccat agtaataaaa atctttatac tttgtgccat
    10081 ctttcttttt cttgatacac ttgttcccaa acattcccac tccacatatc gggcatttta
    10141 caattccaga aagcaagtgt gtgcgtgtat cttttccttt attcacatgc tcatatttct
    10201 ttgcttgaga ttttagctta acctgagcag cttgccaaac ttcatcggaa actatagctt
    10261 catgtatccc ttcagatatt agatattcat cttgttcaac ctgcttatat tcatttcttg
    10321 taccatgaac tttttctaaa gttcttcttc caaatgctat tttcccatta tatacaggat
    10381 tctttaatat ctttcttata agacctgcat caaacaaagg attcttacca ttctgtcttg
    10441 ggatttttct aattccatga ttctctaagt atttagatat cccattggct cctatcgtag
    10501 tatttacata ctggtcgaaa atcgttctta ttgcaactgc ctcttcctca tttataaaca
    10561 gcttgccgtc ttcaagttta tatccatacg gagcaaagcc accattccat tttccttccc
    10621 ttgctttttg aatgcgacct tccattgttt gaatacggat gttttctctt tctatttcag
    10681 ccacagctga taaaacagaa atcattagtt tcccagcatc tttagatgaa tcaatgccat
    10741 cttcaacgca gataagatta actccataat cctgcattat ctgaagtgta gaaagaacat
    10801 cagcggcatt tcttgcaaat cttgataact taaacacaag aacaaaagat actccatctt
    10861 ttccagattt tatatcttcc atcattcgat tgaactgtat tctaccttca atagacttgc
    10921 cagacttccc ggcatcttca tactctccaa caatttcata atcgttgtaa atagcaaaag
    10981 ctttcattcg tgatttttgt gcctctaacg aatacccctc tatctgtatt gacgtagata
    11041 ctcgtgtata gaggtatact tttatttttt cttttgacat agtattaatc tcaatataat
    11101 ttttctatat catatataat ttttttaatt taagtttgga ctatcatttc aagtatatta
    11161 taacactttt attagtccgt ctcaatttgt gtttttgcca tgtcaaaact atttttcatc
    11221 tcttgatttt ttgctggcgt tggatcgggt agattatcta aatctaaagc accagcatat
    11281 tttgcaatca gatttgctat taaatcagcc aatccattcc agtcattgtc caatatatac
    11341 ctcctctaaa gttttatatc taataattat ttgtttaatt aagttttttg acattgacaa
    11401 gtgctttgga ttagcaacat aggaatctca cctccgcctc tattccggat gagccggctt
    11461 caaccttaga agtatcatta tcctcatttt cttcatagcg gatagggtat ccctccctat
    11521 attcaaactc ttacttatcg ctcactttct ttttacttag cagaactttt tttgccgaat
    11581 tattcagccg aaagatcttg acggataggt tattacgctc caaaaataat taacgtcttg
    11641 tcttggtcta ttcaattgtt aaggttcaaa atttatcgag agttattaat ctttttaaaa
    11701 tttgaccatc agaaaatatt tatcttaatg taacaaaatt ctataaatta ccctcttata
    11761 cttaacagtg aaaagaagtc tttcttggta accaattttg aaatagaatt tgcttatata
    11821 aaaaggtcaa attcccactg cataagtagc agtgaaaatt agaccctctt ggtaactgtc
    11881 atctaaaagt cttctagcat ttctttaatt ttctaatcgc ctttaaagtg tcatatttat
    11941 atttttttat ctctggcata ctttgatacc tttttagact taaagtcttt aatagtgcct
    12001 ttccacctct ttttatctat aaagattctc ctacatcata attcattttt ttatttaaac
    12061 ctttctgtct tagtttgtct ttatcttctt cataccattt taagattgtc acatagtggt
    12121 tttgataggt cttaccactg ctttccatgt atctggatag tttatttatc attatatctg
    12181 tgtgtgagtt taatttttct tttagatttt tatattcttc tttgcttaac cttacatttt
    12241 tgaattctcc ataaaaaatg ggggtggact ttttatctat ctctccctct ctctctttat
    12301 ctatctctat atctttccat gtaattccaa tctggagtac ctctactgtc tatcggtaat
    12361 ttaattttga tatctggcaa tactgtgcta gatatttgat ctttatattc agtatttttt
    12421 aaagcttgcc taataattga agttaaatag aatgctactt ctttattcaa ttctttattt
    12481 tttaatttta aacaatgaat tttcatatct aggcttgctt tatatttatg ataaaagact
    12541 gctcctaaaa atgaaacaga tataaaattt tcaaaaactc tataattttt atcatctata
    12601 tcttcgtagt aacctaagat accattgtca atatttgtag cactaattct aggagttttt
    12661 ccatcgagta aatatctttt tggaatagat gagcctgttg gtacttgact cgatttcccc
    12721 tttttttcgg taataaatat ttctttttat tttgttgtct gatatttttc ctacctgtcc
    12781 tttgtaggat gagtattttc tagattttct tgaataactt tttacttgaa gttttagctt
    12841 ttgaactagt cgttgtactt tctttttgtt tattatcagt cctgatcttt ttaatattgc
    12901 tgttattctc tatatcctat ttttcattca tgatattctt ttactaattt tatcttaaat
    12961 tctgtgctgt atttgccatt aaaaaactga cctcctttag ttagtttttt ggcctaactt
    13021 ttgagggtca gttcaaaatt tgcgactttt aaatgaattc caatattcaa ttattaagag
    13081 ctaacatggt gcttgccaat aggaatcatt agaggcgaat tggaaatagg gtcacgtata
    13141 atttttgctt caagattaaa gatatcttta actagtttat catttagtat atcttcaggc
    13201 tttccctctg caacaagttt accttcttta attgcaaata ggtaatcagc gtatcttgct
    13261 gttagattta tatcgtgcaa aatcatgcaa atggttgtct tatatttttg gtttagatca
    13321 gtcaagaggt ctaatagttc tatttgatat gagatatcca agtaagtagt tggctcatct
    13381 aaaagtagga tacttgtatc ttgggctagg gctagagcta tccatactct ttgcctttga
    13441 cccccagaaa gttcttcaac taggttattt gctagatctt caacattggc cttaaccatt
    13501 gatctgttta ttatttcaag gtcatctttt ccaagactct taaaaggctt tctgtagggg
    13561 aaacgaccac ggcttacaag atcagctact gttattgatt cagggattat tggagattga
    13621 ggtaatatag ctatgtgttt tgctaaatct ttttctttat aagaattaat tgatttatta
    13681 tcaagcaata cttctccctc taatggcttt ataagtcgag acaaggtttt aatgagtgtt
    13741 gatttcccac aaccatttga cccaataata actgatattt tttcttcagg tatttttata
    13801 tttatatttt ccaagattat tttttcatca taaccgcagg taagattatt tgaccacaga
    13861 cctttcatta tatattcctc ctgttcattt ttattagtaa gtatattaag tatggtgaac
    13921 ctaacaagcc agttacaaca cctactggat atctagctgg taaaatattt tgagagaata
    13981 tgtctgataa caaaactagt aaaattccaa ccaatccagc taatattggg cttcttttct
    14041 tgccaatatt taaggctatg ggaccagcta aaaaagatat acaagctatt ggtcctgtaa
    14101 ttgaagtaga aaaagcagtt aaagatacag cgcaaaaaat taaaacaagc cttgaaagct
    14161 cgggatttgc tccaagtccg attgctattt cttcaccaag ttcaataatt tctagtcttt
    14221 tattaaaaaa taaaactaat atagtagcaa taatacttac tattagaaca agaggtatgt
    14281 catctaactt tgtaaaagat aaagagccac tgagccatct cataacttct tgtaattcat
    14341 atcttgctac tttcaacaat aaaaatgagg tgcctgctct tgtgacagct tgaaaaccaa
    14401 tacctaatat tatcagtctt gctgctgaaa aaccatcttt tttagctagt aaaaataata
    14461 ttaaagatga tgttagtcca caagttattg aaataattcc agtagttaaa ctatttgttt
    14521 ttaataccaa tatgcaaaag accgctgcaa tagatgaaga acttgtgaca ccgattatat
    14581 caggacttgc aagaggattt cttaacatag tttgaaagat aaatcctgcc aatccaaaag
    14641 accagccagc tataattcct gctaataatt ttggtaatct aatttccata atcgaaaaac
    14701 tagctccagg aacagtttca ctatttaaga ctttaatcaa agttgaaaaa gaataacttt
    14761 catctccgat aagtaaaatg aaaaatgata gactgattat tattaataaa aatagtgagg
    14821 aaaatagtgt tattctattt tttctttttt gaatacctat aattaaattt tgcattagtt
    14881 attaacccct ctatttttca tagttacata aataagtact ggacccccga ttattgcagt
    14941 aattatccct acttcaattt cacctggttt acctaacata cggccgatta tatcacatat
    15001 aagcaagagc tctgcaccta taaaagatga agaaatggtc attgtgcgta tatctttgct
    15061 tataaataag ccacaaaagt gaggaactat aagacctacg aagccaatag gtccaccaat
    15121 tgcagtaata cttgaacata aaagcacact tgcaattatt gcaagtgatc ttatcctatt
    15181 aacattaact ccaagaccaa cagccatttc atcacccata gctaaagcgt ttaaatctga
    15241 tgaaataaat atagctatca agtgacctaa aattataaaa ggtagtagtg tagatataga
    15301 agataatgta gctgctccaa ggctacctat ttgccaaaat ctaaatttgt ctaagacgtt
    15361 attattcggt aaaattaaaa aacttacaaa actgcttaaa gccatactaa cacaagttcc
    15421 tgataaggct agttttatag gggtaaggcc tgcttttccg cttacagcaa tcgcgtatac
    15481 aaaaattgca cttactaagc caccaatgat tgcaaaactt atatggctta tgcttgatga
    15541 aattcctaaa aaagaaagac caattactac actaagactt gctcctgtgt ttataccgag
    15601 tatacctgga tcagctattg ggtttctagt aactgattgc atcaatacac cgcttatggc
    15661 aagactagaa cctgctaaaa ttgcaaaaat agttctaggt attcttttat atataattga
    15721 tttaataaaa tcatcatttg tattgcccat tccaaaagtt gctaaaaaat ctctgatatt
    15781 aatttctttt gttccaagct ttaatgacaa aaatattgta ataagaagac ctaggcagat
    15841 tacaaaaatt atgcctaggt ttatttgttt tttatttcgc atttttgcat gcatttccta
    15901 aaagatttag gtattcttca atagtatagt ttattgaaag tggtgttgga gtgcatgagg
    15961 ctgctaacgg tgtattatct gaaattacag caacggcacc atttttaatt gcatttattt
    16021 tacctaaaag aggatctttt tgtaaagctt caagagtttt atcatcacca taagttatga
    16081 ttacatcagc atcatttatc ttatttgctt cttctgcaga aatttccttt gcaaaactat
    16141 cttcactctc aaattctttt aatgattcag ggaaaactag acctaaatct gttaaataat
    16201 ttgctcttgg atctttgcta gtataaatcc agaattttga tgtatctgca gcattaatca
    16261 tagtaaataa tacttttttt cctttgattt ttcctttgat ttctggatgt ttttctaatt
    16321 ctttggatat acgagcttca gtatttttga ttaactcatc accttctttt tccataccta
    16381 aggcttttga atcaatttta atcatatctc tccataaagt ttgccaaggt ttagatttgt
    16441 atgctgctac aggagcaatt tttgatagag tgtcataatc ttctttagtt ataccagaat
    16501 aacctgctaa gataacatct ggtttagaat ttgatattgc ttcaaagtta agtccatcca
    16561 aatcgtcaaa taggttagct ttaccattta gttctttgat tttttcttct gtccatggta
    16621 aaactccttt atcagcactt acaccgtaat ttgcttttga aaatccaaca ggaactattc
    16681 ctaaagctaa tgctacatca tgatttcccc aagcaatagt tgcaactctt tcaggttttt
    16741 tatctaatat agtttgaccg aaagcatgat ctaaaactat tttatcaggc gcatgctctt
    16801 tagaagtatt ttcttcattt ttaacagaat tagaagaaca agcgctaaaa actatacaca
    16861 tagctaaaat agctattaga aaaaatttgt ttttcataaa aactccttaa acatatttca
    16921 agtctattgt atcgataata attatcattg tcaatagata cagttacaaa tttaataata
    16981 taattttttc aaaaaagg
//
LOCUS       DAVAZT010000049        16132 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVAZT010000049 DAVAZT010000000
VERSION     DAVAZT010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16132
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.049"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            145..6831
                     /locus_tag="VQT45_001612"
     CDS             145..6831
                     /locus_tag="VQT45_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HET2359907.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTVEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQTSNQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDVDVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGFKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVARVRTLIGKEPKMPKTVGFVYSDGSREKLPVTWSQ
                     VDVSQAGVVTVKGTANGREVEAHVEVLAIAKELPTVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRIEQYA
                     KEGVFTVNGRLEDTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQIRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLRFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGKERIFT
                     AINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSEASQTN
                     KAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(7079..7935)
                     /locus_tag="VQT45_001613"
                     /pseudo
     CDS             complement(7079..7935)
                     /locus_tag="VQT45_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8146..8505)
                     /locus_tag="VQT45_001614"
     CDS             complement(8146..8505)
                     /locus_tag="VQT45_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HET2359908.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            8597..9553
                     /locus_tag="VQT45_001615"
                     /pseudo
     CDS             8597..9553
                     /locus_tag="VQT45_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            9537..10094
                     /locus_tag="VQT45_001616"
     CDS             9537..10094
                     /locus_tag="VQT45_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2359909.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQADLTNAQLILQGHETLDQFVIKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            10087..10341
                     /locus_tag="VQT45_001617"
     CDS             10087..10341
                     /locus_tag="VQT45_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359910.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERSVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            10353..12407
                     /locus_tag="VQT45_001618"
     CDS             10353..12407
                     /locus_tag="VQT45_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HET2359911.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            12586..13446
                     /locus_tag="VQT45_001619"
     CDS             12586..13446
                     /locus_tag="VQT45_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HET2359912.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLCFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            13657..14367
                     /gene="ccdA2"
                     /locus_tag="VQT45_001620"
     CDS             13657..14367
                     /gene="ccdA2"
                     /locus_tag="VQT45_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET2359913.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            14387..14953
                     /locus_tag="VQT45_001621"
     CDS             14387..14953
                     /locus_tag="VQT45_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HET2359914.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            14964..16076
                     /gene="msrB"
                     /locus_tag="VQT45_001622"
     CDS             14964..16076
                     /gene="msrB"
                     /locus_tag="VQT45_001622"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET2359915.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
BASE COUNT         4901 a         3052 c         3565 g         4614 t
ORIGIN      
        1 catatctacg gcaaggcgac actgacgaag tttgaattgg attttcgcag agtgtaaatt
       61 gttgaaacta ggttgtcata ccatgtatac cacttgggct ttggtagtag ctaactgcac
      121 taaatataat ataaggaggg ttttatgggg aaaggccatt ggaatcggaa aagagtttat
      181 agcattcgta agtttgctgt gggagcttgc tcagtaatga ttgggacttg tgcagttcta
      241 ttaggaggaa atatagctgg agaatctgta gtttatgcgg atgaaacact tattactcat
      301 actgttgaga aacctaaaga ggaaaaaatg atagtagaag aaaaggctga taaagctttg
      361 gaaactaaaa atgtagttga aaggacagaa caaagtgaac ctagttcaac tgaggctatt
      421 gcatctgaga agaaagaaga tgaagccgta actccaaaag aggaaaaagt gtctgctaaa
      481 ccggaagaaa aagctccaag gatagaatca caaacttcaa atcaagaaaa accgctcaag
      541 gaagatgcta aagctgtaac aaatgaagaa gtgaatcaaa tgattgaaga caggaaagtg
      601 gattttaatc aaaattggta ttttaaactc aatgcaaatt ctaaggaagc cattaaacct
      661 gatgtagacg tatctacgtg gaaaaaatta gatttaccgt atgactggag tatctttaac
      721 gatttcgatc atgaatctcc tgcacaaaat gaaggtggac agctcaacgg tggggaagct
      781 tggtatcgca agactttcaa actagatgaa aaagacctca agaaaaatgt tcgccttact
      841 tttgatggcg tctacatgga ttctcaagtt tatgtcaatg gtcagttagt ggggcattat
      901 ccaaatggtt ataaccagtt ctcatatgat atcaccaaat accttcacaa agatggtcgt
      961 gagaatgtga ttgctgtcca tgcagtcaac aaacagccaa gtagccgttg gtattcagga
     1021 agtggtatct atcgtgatgt gactttacaa gtgacagata aggtgcatgt tgagaaaaat
     1081 gggacaacta ttttaacacc aaaacttgaa gaacaacaac atggcaaggt tgaaactcat
     1141 gtgaccagca aaatcgtcaa tacggacgac aaagaccatg aacttgtagc cgaatatcaa
     1201 atcgttgaac gaggtggtca tgctgtaaca ggcttagttc gtacagcgag tcgtacctta
     1261 aaagcacatg aatcaacaag cctagatgcg attttagaag ttgaaagacc aaaactctgg
     1321 accgttttaa atgacaaacc tgccttgtac gaattgatta cgcgtgttta ccgtgacggt
     1381 caattggttg atgctaagaa ggatttgttt ggttaccgtt actatcactg gactccaaat
     1441 gaaggtttct ctttgaatgg tgaacgtatt aaattccatg gagtatcctt gcaccacgac
     1501 catggggcgc ttggagcaga agaaaactat aaagcagaat atcgccgtct caaacaaatg
     1561 aaggagatgg gagttaactc catccgtaca acccacaacc ctgctagtga gcaaaccttg
     1621 caaatcgcag cagaactagg tttactcgtt caggaagagg cctttgatac ttggtatggt
     1681 ggcaagaaac cttatgacta tggacgtttc tttgaaaaag atgccactca cccagaagct
     1741 cgaaaaggtg aaaaatggtc tgattttgac ctacgtacca tggtcgaaag aggcaaaaac
     1801 aaccctgcta tcttcatgtg gtcaattggt aatgaaatag gtgaagctaa tggtgatgcc
     1861 cactctttag caactgttaa acgtttggtc aaggttatca aggatgttga taagactcgc
     1921 tatgttacca tgggagcaga taaattccgt ttcggtaatg gtagcggagg gcatgagaaa
     1981 attgctgatg aactcgatgc tgttggattt aactattctg aagataatta caaagccctt
     2041 agagctaagc atccaaaatg gttgatttac ggttcagaaa catcttcagc tacccgtaca
     2101 cgtggaagtt actatcgccc tgaacgtgaa ttgaaacata gcaatggacc tgagcgtaat
     2161 tatgaacagt ctgactatgg aaatgatcgt gtgggttggg ggaaaacagc aaccgcttca
     2221 tggacttttg accgtgacaa cgctggctat gctggacagt ttatctggac aggtacggac
     2281 tatattggtg aacctacacc atggcacaac caaaatcaaa ctcctgttaa gagctcttac
     2341 tttggtatcg tagatacagc cggcattcca aaacatgact tctatctcta ccaaagccaa
     2401 tgggtttctg ttaagaagaa accgatggta caccttcttc ctcactggaa ctgggaaaac
     2461 aaagaattag catccaaagt agctgactca gaaggtaaga ttccagttcg tgcttattcg
     2521 aatgcttcta gtgtagaatt attcttgaat ggaaaatctc ttggttttaa gactttcaat
     2581 aaaaaacaaa ccagcgatgg gcggacttac caagaaggtg caaatgctaa tgaactttat
     2641 cttgaatgga aagttgccta tcaaccgggt accttggaag caattgctcg tgatgaatct
     2701 ggcaaggaaa ttgctcgaga taagattacg actgctggta agccagcggc agttcgtctt
     2761 attaaggaag accatgcgat tgcagcagat ggaaaagact tgacttacat ctactatgaa
     2821 attgttgaca gccaggggaa tgtggttcca actgctaata atctggttcg cttccaattg
     2881 catggccaag gtcaactggt cggtgtagat aacggagaac aagccagccg tgaacgctat
     2941 aaggcgcaag cagatggttc ttggattcgt aaagcattta atggtaaagg tgttgccatt
     3001 gtcaaatcaa ctgaacaagc agggaaattc accctgactg cccactctga tctcttgaaa
     3061 tcgaaccaag tcactgtctt tactggtaaa aaagaaggac aagagaagac tgttttgggg
     3121 acagaagtag caagagttcg tacattaatt ggtaaagaac caaaaatgcc gaaaacagta
     3181 ggttttgtat acagcgatgg tagtcgtgaa aaacttccag taacttggtc tcaagtcgat
     3241 gttagtcaag caggagttgt gactgttaaa ggtacagcaa atggacgtga ggtagaggct
     3301 catgtcgagg ttctagcaat tgcgaaagaa ttaccaacag ttaaacgtat tgctccaaat
     3361 actgacttga attctgtaga caaatctgtt tcttatgttt tgactgatgg aagtgtacaa
     3421 gagtacgaag tagatagctg ggagattacg gaagtagata aagccaaact ttcagtagct
     3481 ggatcacgta ttcaaatgac tggtcagtta gctggagaaa ctattcatgc aacccttgtg
     3541 gtagaagaag gaaatgctgc agcacctgta gtgccaactg ttactgttgg aggtgaggca
     3601 gtaacaggtc ttactagtcg acaaccaatg caatatcgta ctctatctta tggtgcccaa
     3661 ctgccagaag tcacagcaag tgctgaaaat gctgatgtga cagttcttca agcaagcgca
     3721 gcaaacggca tgcgtgcgag catctttatt cagcctaaag atggtggtcc tcttcaaacc
     3781 tatgcaattc aattcctaga agaagcacca aaaattgctc acttgagttt gcaagtggaa
     3841 aaagctgaca gtctcaaaga agaccaaact gtcaaattgt cggttcgagc tcactatcaa
     3901 gatggaacgc aagctgtatt accagctgac aaagtaacct tctctacaag tggtgaaggg
     3961 gaagtcgcaa ttcgtaaagg aatgcttgag ttgcataagc caggagcagt cactctcaaa
     4021 gcggaatatg agggagctaa aggccaagtt gaactcacta tccaagccaa tactgagaag
     4081 aagattgcgc aatctatccg tcctgtaaat gtagtcacag atttgcatca aaaacctact
     4141 cttccaacaa cagtaacggt tgagtatgac aaaggtttcc ctaaagctca caaagtcact
     4201 tggcaagcta ttccgaaaga aaaactagac tcctatcaaa catttgaagt actaggtaaa
     4261 gttgaaggaa ttgaccttga agcgcgtgca aaagtctctg tagaaggtat cgtttcagtt
     4321 gaagaagtca gtgtgacaac tccaatcgca gaagcaccac aattaccaga aagcgttcgg
     4381 acatatgatt caaatggtca cgtttcatca gctaaggttg catgggatgc gattcgtata
     4441 gagcaatacg ctaaggaagg tgtctttaca gttaatggtc gcttagaaga tactcaatta
     4501 acaactaaac ttcatgttcg cgtatctgct caaactgagc aaggtgcaaa catttctgac
     4561 caatggaccg gttcagaatt gccacttgcc tttgcttcag attcaaatcc aagcgaccca
     4621 gtttcaaatg ttaatgacaa gctcatttcc tacaataacc aaccagccaa tcgttggaca
     4681 aactggaatc gtactaatcc agaagcttca gtcggtgttc tgtttggaga ttcaggtatc
     4741 ttgagcaaac gctccgttga taatctaagt gtcggattcc acgaagacca tggagttggt
     4801 gcaccgaagt cttatgtgat tgagtattat gttggtaaga ctgtcccaac agctcctaaa
     4861 aaccctagtt ttgttggtaa tgaggaccat gtctttaatg attctgccaa ctggaaacca
     4921 gttactaatc taaaagcccc tgctcaactc aaggctggag aaatgaacca ctttagcttt
     4981 gataaagttg aaacctatgc tgttcgtatt cgcatggtta aagcagataa caagcgtgga
     5041 acgtctatca cagaggtaca aatctttgcg aaacaagttg cggcagccaa acaaggacaa
     5101 ataagaatcc aagttgacgg caaagactta gcaaacttca accctgattt gacagactac
     5161 taccttgagt ctgtagatgg aaaagttccg gcagtcacag caagtgttag caacaatggt
     5221 ctcgctaccg tcgttccaag cgttcgtgaa ggtgagccag ttcgtgtcat cgcgaaagct
     5281 gaaaatggcg acatcttagg agaataccgt ctgcacttca ctaaggataa gaacttactt
     5341 tctcataaac cagttgctgc ggttaaacaa gctcgcttgc tacaagtagg tcaagcactt
     5401 gaattgccga ctaaggttcc agtttacttc acaggtaaag acggctacga aacaaaagac
     5461 ctgacagttg aatgggaaga agttccagca gaaaatctga caaaagcagg tcaatttacc
     5521 gttcgaggcc atgtccttgg tagtgatctt gttgctgagg tcactgtacg agtgacagac
     5581 aaactaggcg aagctctttc agataaccct aactatgatg aaaacagtaa ccaggccttt
     5641 gcttcagcaa ccaatgatat tgacaaaaac tctcatgacc gcgttgacta tctcaatgac
     5701 ggagatcatt cagaaaatcg tcgttggaca aactggtctc caacaccatc ttctaatcca
     5761 gaagtatcag cgggtgtgat cttccgtgaa aatggtaaga ttgtagaacg gactgttgcc
     5821 caagccaaac ttcgtttctt tgcagatagt ggtacggatg caccaactaa actcgtttta
     5881 gaacgctatg tcggtccaga gtttgaagtg ccaacctact attcaaacta ccaagcctac
     5941 gacgcagacc atccattcaa caatccagaa aattgggaag ctgtgcctta tcgtgcggat
     6001 aaagacatcg cagctggtga tgaaatcaac gtaacattta aagctgtcaa agccaaagct
     6061 atgagatggc gtatggagcg taaagctgac aagagcggtg ttgcgatgat tgagatgacc
     6121 ttccttgcac cgagtgaatt gcctcaagaa agtacgcaat cgaagattct tgtagatgga
     6181 aaagaacttg ctgatttcgc tgaaaatcgt caagactatc aaattaccta taaaggtcaa
     6241 cggccaaaag tctcagttga agaaaacaat caagtagctt caactgtggt agatagtgga
     6301 gaagatagcc ttccagtact tgttcgcctc gtttcagaaa gtggaaaaca agtcaaggaa
     6361 taccgtatcc agttgactaa ggaaaaacca gtttctgctg tacaagaaga tcttccaaaa
     6421 ctcgaatttg ttgaaaaaga tttggcctac aagacagttg agaaaaaaga ttcaacactg
     6481 tatctaggtg aaactcgtgt agaacaagaa ggaaaaactg gtaaagaacg tatctttaca
     6541 gcgattaatc ctgatggaag taaggaagaa aaactccgtg aagtggtaga agctccgaca
     6601 gaccgcatag tcttggttgg aaccaaacca gtagctcaag aagctaaaaa accacaagtg
     6661 tcagaaaaag cagatacaaa accaattgat tcaagtgaag ctagtcaaac taataaagcc
     6721 cagttaccaa atacaggtag tgcggcaagc caagcagcag tagcagcagg tttagctctt
     6781 ctaggtttga gtgcaggatt agtagttact aaaggtaaaa aagaagacta gaaattttga
     6841 taccttcttt atcattaaag accaaagaaa aactcttgtc ctaaatagaa gataaagagt
     6901 ctggaacaaa atagttctca accacaaaaa agctagatat ttccaattgc ggaactctag
     6961 ctttttaatt ttgagtcgtt ctcttattgt atagtagatt gaaactagaa tagtacactt
     7021 ctacttctaa aacattgtta gaaatcaatt tgactgtcct tatcgatttg tcctgttctt
     7081 atttcatttc actatgtttt aggaggttat tggccataag taccaatccc atgtcaattc
     7141 tcacttgacg cttccctctc agattacatc tcttgtaacc caaacaagcc tttatctgcc
     7201 caaagacagg ttccacatca atcttgcgtt gagcgaaaat ctgtctacct tggggagata
     7261 aaagcgcctg acattcttta gctttcaagt tttgatagcg ttcgttcata tacagtccct
     7321 tttgagggac tgattcaggt tcatcagcgt agtaaacctt gatttcctgt tgaaagtctg
     7381 tctgtgtttt ctggtacttg atatggtgaa aacgatagca ccagccatca ggatgtgtgt
     7441 agctatcctc cttgtcatta tagtgccaat tcgctaagtt tttagctgac tgtttatacc
     7501 ctctcttttg ttccttatca aacatggcat atttaatcag aaggggagtg atttcttctt
     7561 gaaaatagac ctgtatctgt tcttgaagtt tggcggagaa tttctctgtc gttttcttcc
     7621 acacaaaact atacttgttg gcattggctt caatcttagt tccgtcaata aacaaacaat
     7681 ctaaggtcac taactcttcc atttttcaat ttttcgacca gagaaaatcc cttgtgaata
     7741 ggcaaataga agagtagata caagcatttt agggtgataa gacgggcgat caaaggcatg
     7801 atagaaggcg tggaagtgac aatcctccaa ggtattcacc actttttcaa tagtaaaaac
     7861 gagatgatct tgtggcaaga aggaactgat ttctagtggt aaagttgttt gatttgtgtt
     7921 atagtgaata tgcatgggat agcctttcta aatggtttat taagcaattc tattttacca
     7981 agactatcgc aaccatgcaa aaaagcaacg gcaaatccgt tgcctttttt ggagataaga
     8041 gactattgtc ccagactctt ttctttgtat aaaattgtat agtgttattg tctatactat
     8101 tttgtagaga aagcaaaaat ccctagaaaa tgcttaggga ttcgactatt tcattaagaa
     8161 caattcaaca atcatttcta tatacatgat aagggttaat aagaatcctg cacgccagaa
     8221 gaatttgata aatttaggat agtaaaagct gcgttttttc aaaaggaaga aaaagacgag
     8281 aataatggct aggatcgaga gggctagccc cagtctaggg aggaaattat gggtaaaggt
     8341 tttagctgta atcaagtaat actcaaatac caagactgga aaagccaaat ccgcaaagtt
     8401 tcgtcctagt ttttttaatc taaaaagttt ggttaggata atgcagacga ctaaggtcag
     8461 tatcaataat aaaatagatg ctaatttcat taaaatcata cccatattgt atcataaaaa
     8521 aaggctaatg gaaacgagaa acagaggaat ttataggaaa gtcaggcttt tgagattgtg
     8581 ggtgattttt gttataatga aagttataaa atcttataat accttgaatg attattatcg
     8641 aaaactcttt ggagaaaaga cttttaaagt ccctattgat gcgggatttg actgtcccaa
     8701 tcgtgatgga actgtggctc atggaggctg tactttttgt acggtttccg gttctggaga
     8761 tgccattgtg gcaccagatg cgcctatccg tgagcaattt tataaggaaa ttgactttat
     8821 tcatcgtaag tggccagatg ttcagaagta tctggtttat tttcaaaatt ttaccaacac
     8881 ccatgaaaag gtggaagtta ttcgagagcg ttatgaacag gctatcaatg agccaggtgt
     8941 ggtaggaatc aatattggaa cgcgcccaga ctgtttacca gacgaaacca tcgaatattt
     9001 ggctgagtta tcggagtgca tgcatgtgac ggttgaattg ggcttgcaaa ctacttatga
     9061 agcaacctct gacctgatta accgtgcgca ttcttatgaa ttgtaggtgg aaacggtcaa
     9121 gcgtttgaga aagtatccaa aaattgagat tgtttcccat ttgatcaatg gtttgcctgg
     9181 tgaaacccat gagatgatgg ttgaaaatgt ccgccgttgt gtcacggata acgatattca
     9241 agggattaaa ctgcatttgc tccatcttat gacaaatact cgtatgcaac gagattacca
     9301 tgaggggcgt ttacaattga tgagtcagga cgaatatgtc agggtcatct gtgaccaact
     9361 ggaaattatt cccaaacata tcgtcatcca tcgaattaca ggagatgcgc ctagggatat
     9421 gctgcttggg cctatgtgga gcctcaataa atgggaagct ctcaacagca ttgagatgga
     9481 gatgcgacgt cgtggaagtg ttcaaggatg caaggctgta aaacaggagt ttgaaaatga
     9541 aaagaccact tgagatggca catgattttt tggctgaggt cgtgacaaaa gaggatgtcg
     9601 tagtggatgc gactatggga aatggtcatg acacgctttt tttagccaag ctagccaagc
     9661 aagtctatgc ctttgatatt cagaagcaag ccttggaaaa gacccaagag cgtttgcatc
     9721 aggctgactt gacaaatgcc cagttaatct tgcaaggcca tgagacactg gaccagtttg
     9781 tgataaaagc taaggcaggg atttttaatc tgggctattt gccgtcagct gataagtctg
     9841 tcatcacccg accgcagaca acgattgagg cattagaaaa gctatgtggc ttacttgtca
     9901 aaggtggacg aattgctatt atgatttact atggtcatga aggaggcgat ctcgagagag
     9961 atgctgtctt ggattttgtg atccagttga accaacaaga gtacacagct gccatttacc
    10021 gaactttaaa ccaagtcaac aacccgccgt ttttagtgat gattgaaaaa ttagagagat
    10081 acagacatgg ataaacaata cctacacgaa aagctggatg ccatgcgcca gaattttgtt
    10141 gaatcaaccc accacgaacg atcggtgggc gtgctagacc aagcgcatat gagcaaaaaa
    10201 atgcttaaaa tcaagaaaaa attagttgct cttgaaatgg aacggtgcca gagaaaaatt
    10261 gagcacaaag actgttccaa gattgaccaa aaaatcaaag agcagaagga gatatttgaa
    10321 tcctgttgta aaaaagatta aggaggacgt gcgtggaatt actgatttac ctcatcctat
    10381 ttttactggt tttgattgtc tcaagtacaa ccaataagct cctgcccttt ttgcctctcc
    10441 ctttggtgca gattcttttg ggaattgtga ttggtctctt tttacccaat actgactttc
    10501 accttaatac ggagttgttt ttggcactgg ttatcggacc cttgcttttc cgagaggctg
    10561 aagaagcaga tgttacggct attttaaaac actggcgaat cattgtttat ctcatatttc
    10621 cagtgatttt tatctcgacc ttgagtttgg gtggcttggc ccatcttctt tggttcagcc
    10681 ttcccttggc agcttgcttg gctgttgggg cagcccttgg tcctacggac ttggtggcct
    10741 ttgcctctct ttcggagcgt tttagctttc ctaagcgcgt gtccaatatt cttaagggcg
    10801 aaggactctt gaatgatgct tctggtttgg tggcttttca ggtagctttg acagcttgga
    10861 caactggagc tttttctctg gggcaagcta gcagttcgct catcttttca atcctaggcg
    10921 gttttttaat tggattttta acggccatga ccaaccgctt cctccatacc ttcttgctaa
    10981 gtgtgcgcgc aacggatatt gccagtgaac ttttattaga attgagtttg cctctagtga
    11041 ccttctttct ggcagaagaa gttcatgttt caggtattat tgccgtcgta gttgctggaa
    11101 ttttaaaggc aagtcgcttc aagaaaatca cgctcctcga agcccaagtg gatacggtga
    11161 ccgagacggt ctggcataca gtgaccttta tgctcaacgg ttctgtcttt gtgattttag
    11221 ggatggagtt ggaaatgata gcagaaccta tcttgaccaa tccaatctat aatcctctac
    11281 ttttattgct atctctcatc gcccttacct ttgtcctctt tgtcattcgt tttattatga
    11341 tctatggcta ttatgcctat agaacccgac gcctcaagaa aaagctaaat aagtatatga
    11401 aggacatgtt tctcttgacc ttttcaggtg ttaagggaac ggtgtcgatt gctacgattc
    11461 tcttgatacc aagtaatcta gaacaggagt atcctctttt gcttttcctt gttgcaggtg
    11521 tgacgcttgt cagcttttta acaggtctct tggtcttgcc tcatctttct gatgaagagg
    11581 aagaaagcaa ggattatctc atgcatatcg ccattttgaa tgaagtaacg ctagagttgg
    11641 aaaaagagtt ggaagacacc agaaataaac ttcccctcta tgcggctatt gacaattatc
    11701 atggacgtat tgaaaatctc attttaagcc aagaaaacca ggatgatcaa gaagattggg
    11761 ctgctttgaa actcttgatt cttagtattg aaagtgatgg tttggaacag gcctatgaag
    11821 aggggaacat tagcaatcgt gcttaccgag tttaccaacg ttatctgaaa aatatagaac
    11881 aaggaatcaa tcgtaaactt gcctcaagac tgacctatta ttttcttgtt tccttgagga
    11941 ttttacgttt tctccttcat gaagttttta ctcttggaaa gaccttccgt agctggaagg
    12001 acaaggagca aagccgtctc cgtgctcttg attatgacca aattgcagag ctctatcttg
    12061 ccaatacaga gatgattatt gaaagtttgg aaaacctgaa gggagtctac agacgctctt
    12121 tgattagttt tatgcaggag tctcgtcttc gagaaacagc tattatcagc agtggtgcct
    12181 ttgtcgaacg ggttatcaat cgtgtcaaac ccaacaatat cgatgaaatg ctgagaggct
    12241 attatctgga gcgcaagttg attttcgaat acgaagaaaa acgattgatt acgactaagt
    12301 atgccaagaa attacgacaa aatgtaaata acttagagaa ctattccttg aaggaagctg
    12361 ccaataccct gccgtatgat atggtggaat tggtaagaag aaattagtta atactcttcg
    12421 aaaatctctt caaaccacgt cagcgtcgcc ttggattata tatgtgactg acttcgtcag
    12481 tttcatctac aacctcaaag cagggctttg agcaacctgc ggctagcttc ctagtttgct
    12541 ctttgatttt cattgagtat aagattataa atgaaggagt atgacatgaa aaagtggtgg
    12601 aaagagctga tagacaagcc tttattaaaa gcttttttgc attattatca agcatcagat
    12661 agtgagttga ccagtgtcgc agtagcctac tattggttga tttcgatttt ccccctgctt
    12721 ttggtggtgg tcaatatcct cccctatttt cagattcctg tgggagaatt tctgtgcttt
    12781 atgaaagacg ttctgccccc aagcctctat gaaggtgtgg aaaaaatagc cagagaagtt
    12841 ttgacgcaac cttcaacagg tttattgagt ttttctgttt tatcggcgtt atggagtttt
    12901 tcaaaatcta tgaatttctt gcaaaaagct tttaacaagg cttatggcgt cgaaaagagt
    12961 cgtggactta tttcccatca gatgctaagt ctcctagtca gttttggctt gcagctcctc
    13021 tttgcgtttg ccttgttttt gatcttattt ggtcagatga ttttggcttt acttgctcat
    13081 tattggacaa aagatggcat tatctatcag gctttacaag ggttggcagg tcctctgatt
    13141 tacgccctcc tctttgctat cttggtcatg ctttattatt ttcttcccaa tctatctaac
    13201 aggaaaatta gctataccct accaggcagt gcctttgttc tcttagtgat tttaggttta
    13261 ctaactctgt tctctagtta tctcaattac tatgtccatc atttggtgga tgtccgaatt
    13321 ttaggttccg ttcttcttgt tgttatgatg ttttggttta tcttgattgc taaaattgtt
    13381 atcctaggcg cggttatcaa tgccagtatg cagagtttga aagatccggt ctttaaaaaa
    13441 gactaactat ttatccatta caaaagcgca tagtatcaaa actttataga accttgatac
    13501 tatgcgcttt tgtgctttga cagttttttg tatagttttt gtccaagatt tctaaatcat
    13561 ctgattaaat tcctattttc ccctatcatt gtccctgttt tttcgaaaat ggaaggagta
    13621 taataaatct atcaataaaa tgataggagg aactttatgg gtcatatttt cttttttcta
    13681 agtgtctttt tggcagggat tctatccttc ttttctcctt gtatcttacc tttgttaccg
    13741 gtctatacag gagtgttact agatgataag gatggtgctc aggcttctag cggcaaattt
    13801 tcaatctcag ttactagttt attacgaact ctggccttta tagcaggaat ttcctttata
    13861 tttattttgt tgggctatgg agctggtttt ttaggcgatt tgctttatgc ttcttggttc
    13921 caatatctta ctggggcaat tattatcctt cttggtttgc accaaatgga gattctacac
    13981 tttaaggggc tttataagga aaagaggcta caactgcaag gacaggggca aaatggtaag
    14041 ggctatagtc aggcattttt attgggcttg acctttagtt ttgcttggac gccttgcgtg
    14101 gggccggttc tggggtctgt tttggccttg gcggcttcag gtggttcagg agcttggcag
    14161 ggagctggtc tcatgttggt gtatacgctg ggcttggcgc taccattctt gcttctagct
    14221 ctgacctcta gttatgtttt gaaacatttc cgaaaacttc atccctatct cggaatcctc
    14281 aaaaaagtgg gtggttttct cattattgtg atgggactct tggttctgtt tggaaatgct
    14341 tcaattttaa gtcaattatt tgaataaaat ggaaaggaat atcaatatga aaaaatggca
    14401 aacatgtgtt cttggagcag gttcgctcct ttgtttgacg gcttgttcag gcaagtccgt
    14461 gactagtgaa caccaaacga aagatgaaat gaagacggag cagacagcta gtaaaacaag
    14521 cgcagctaaa gggaaagagg tggctgattt tgaattgatg ggagtagatg gcaagaccta
    14581 ccgtttatct gattacaagg gcaagaaagt ctatctcaaa ttctgggctt cttggtgttc
    14641 catctgtctg gctagtcttc cagatacgga tgagattgct aaagaagctg gtgatgacta
    14701 tgtggtcttg acagtagtgt caccaggaca taagggagag caatctgaag cggactttaa
    14761 gaattggtat aagggattgg attataaaaa tctcccagtc ctagttgacc catcaggcaa
    14821 acttttggaa acttatggtg tccgttctta cccaacccaa gcctttatag acaaagaagg
    14881 caagctggtc aaaacacatc caggattcat ggaaaaagat gcaattttgc aaactttgaa
    14941 ggaattagcc taggaggtgt cttatgaatg ataagttaaa aatcttcttg ttgctaggag
    15001 tattttttct agccataacc ggtttctatg ttctattgat acgaaatgca gggcagacag
    15061 atgcctcgca aattgaaaag gcggcagtta gccaaggagg aaaagcagtg aaaaaaacag
    15121 aaattagtaa agacgcagac ttgcacgaaa tttatctagc tggaggttgt ttctggggag
    15181 tggaggaata tttctcacgc gttcccgggg tgacggatgc cgtttcaggc tatgcaaatg
    15241 gtagaggaga aacaaccaag tacgaattga ttaaccaaac aggtcatgca gaaaccgtcc
    15301 atgtcaccta tgatgccaag caaatttctc tcaaggaaat cctgcttcac tatttccgca
    15361 ttatcaatcc aaccagcaaa aataaacaag gaaatgatgt ggggacccag taccgtactg
    15421 gtgtttatta cacagatgac aaggatttgg aagtgattaa ccaagtcttt gatgaggtgg
    15481 ctaagaaata cgatcaacct ctagcagttg aaaaggaaaa cttgaagaat tttgtggtgg
    15541 ctgaggatta ccatcaagac tatctcaaga aaaatccaaa tggctactgc catatcaatg
    15601 ttaatcaggc ggcctatcct gtcattgatg ccagcaaata tccaaaacca agtgatgagg
    15661 aattgaaaaa gaccctgtca cctgaggagt atgcagttac ccaggaaaat caaacagaac
    15721 gagctttctc aaaccgttac tgggataaat ttgaatccgg tatctatgtg gatatagcaa
    15781 ctggggaacc tctcttttca tcaaaagaca aatttgagtc tggttgtggc tggcctagtt
    15841 ttacccaacc catcagtcca gatgttgtca cctacaagga agataagtcc tacaatatga
    15901 cgcgtatgga agtgcggagc cgagtaggag attctcacct tgggcatgtc tttacggatg
    15961 gtccacagga caagggcggc ttacgttact gtatcaatag cctctctatc cgctttattc
    16021 ccaaagacca aatggaagaa aaaggctacg cttatttact agattatgtt gattaatact
    16081 cttcgaaaat ctcttcaaac cacgtcagcg tcgccttacc gtatgtaggg tt
//
LOCUS       DAVAZT010000050        16071 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVAZT010000050 DAVAZT010000000
VERSION     DAVAZT010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16071)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16071)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16071
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.050"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            63..527
                     /locus_tag="VQT45_001623"
     CDS             63..527
                     /locus_tag="VQT45_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HET2359916.1"
                     /translation="MGGHPGFNCLLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            685..1110
                     /gene="lacA"
                     /locus_tag="VQT45_001624"
     CDS             685..1110
                     /gene="lacA"
                     /locus_tag="VQT45_001624"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HET2359917.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            1141..1656
                     /gene="lacB"
                     /locus_tag="VQT45_001625"
     CDS             1141..1656
                     /gene="lacB"
                     /locus_tag="VQT45_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HET2359918.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1667..2596
                     /locus_tag="VQT45_001626"
     CDS             1667..2596
                     /locus_tag="VQT45_001626"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HET2359919.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDDQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKLVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLEELKEVLQESLFTGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAGLLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            2598..3578
                     /gene="lacD"
                     /locus_tag="VQT45_001627"
     CDS             2598..3578
                     /gene="lacD"
                     /locus_tag="VQT45_001627"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HET2359920.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKILVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            3812..4648
                     /locus_tag="VQT45_001628"
     CDS             3812..4648
                     /locus_tag="VQT45_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET2359921.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENH
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALIQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            4684..5001
                     /locus_tag="VQT45_001629"
     CDS             4684..5001
                     /locus_tag="VQT45_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2359922.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            5003..6697
                     /locus_tag="VQT45_001630"
     CDS             5003..6697
                     /locus_tag="VQT45_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET2359923.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERSGKSNDELKEKVAANFNTAKADAILEKA
                     GVDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQAQFD"
     gene            6906..8312
                     /gene="lacG"
                     /locus_tag="VQT45_001631"
     CDS             6906..8312
                     /gene="lacG"
                     /locus_tag="VQT45_001631"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET2359924.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPLDPKNPSDVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            8355..8537
                     /locus_tag="VQT45_001632"
     CDS             8355..8537
                     /locus_tag="VQT45_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HET2359925.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLFLNFINPEE
                     WDTISFDSDFMPFQQS"
     gene            complement(8815..9576)
                     /locus_tag="VQT45_001633"
     CDS             complement(8815..9576)
                     /locus_tag="VQT45_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2359926.1"
                     /translation="MLKQEKLAKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(9758..10720)
                     /gene="nrdF"
                     /locus_tag="VQT45_001634"
     CDS             complement(9758..10720)
                     /gene="nrdF"
                     /locus_tag="VQT45_001634"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HET2359927.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(10908..13067)
                     /gene="nrdE"
                     /locus_tag="VQT45_001635"
     CDS             complement(10908..13067)
                     /gene="nrdE"
                     /locus_tag="VQT45_001635"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HET2359928.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(13148..13366)
                     /gene="nrdH"
                     /locus_tag="VQT45_001636"
     CDS             complement(13148..13366)
                     /gene="nrdH"
                     /locus_tag="VQT45_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HET2359929.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            13717..13980
                     /locus_tag="VQT45_001637"
     CDS             13717..13980
                     /locus_tag="VQT45_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HET2359930.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            13986..15719
                     /gene="ptsP"
                     /locus_tag="VQT45_001638"
     CDS             13986..15719
                     /gene="ptsP"
                     /locus_tag="VQT45_001638"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HET2359931.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            15974..>16071
                     /locus_tag="VQT45_001639"
     CDS             15974..>16071
                     /locus_tag="VQT45_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2359932.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTV"
BASE COUNT         5025 a         2818 c         3331 g         4897 t
ORIGIN      
        1 aactagaatt ctagttttgc aggaagtcta ataaagaaac tagcaaggtc aggccttact
       61 ttattggtgg acatccagga tttaattgtc ttctacttga tgatgaagtc tatgaagatt
      121 attatctaga gtttgagaaa gaagagattt gctctgttcc acgtcctttc ccagaaacag
      181 gtatgttgga tttccaagat agaagtccat ggctagaggg acaaaaagaa atagatctta
      241 gttatgatct tttcagcaca gatgcagtga ctttggatga attgcaatct cgaacaattg
      301 cccttcgttc tcttaaacat gataagggat tgaaagtgca ttttgcagaa tttccaaacc
      361 tcatcatctg gtcaactttg aacaagggac ctttcattac ctttgaacca tggtctggct
      421 tgtcaacatt ccttgaagaa ggagatcatt tagaagataa gaagaatgtt tgtctcttag
      481 aagccaatca ggttgaagaa ttagggtttg agatagaagt tttataaaaa aagtaaaaaa
      541 taaataacaa aaacaaacac aaactgttga cttcttcaaa caatagtagt atattatgtt
      601 tgtgaggact aattgactgt tttttaaaga cagccaatac actgctggaa tccagcatag
      661 aaaaaataaa aaggagtata caatatgtct attgttatcg gtgcagatgc tgcaggtttg
      721 agattgaaag aagttgtgaa agacttctta gaaaaagaaa acttccacct tgtggatgtt
      781 acagctgaag gtcaagactt tgttgatgtg actctcgctg ttgctgcaga agtaaacaaa
      841 gaagaacaaa accttggtat cgtgattgat gcttatggag ctggtccatt tatggttgca
      901 actaagatca aaggaatggt tgctgcagaa gtatctgacg aacgttcagc ttatatgact
      961 cgtggccaca acaactcacg tatgatcact atgggggcac aacttgttgg tgatgaattg
     1021 gctaaaaaca tcgctaaagg atttgttaat ggtaaatacg acggtggacg tcatcaaatc
     1081 cgggttgaca tgttgaacaa aatgggctaa ttagattaca gtaagaaagg taagttaaaa
     1141 atgagaattg caattggatg cgaccacatc gtaacagatg aaaaaatggc ggtttcagaa
     1201 tttttgaaat caaaaggata tgaagtcatt gactttggta catatgacca tacacggact
     1261 cactacccaa tctttggtaa aaaagtaggg gaagctgtaa ctagcggcca agctgatctt
     1321 ggggtatgta tctgtggtac tggtgttggt atcaacaacg ctgtaaataa agttccaggt
     1381 gttcgttctg ccttggttcg tgatatgaca acagcccttt atgctaaaga acaattgaac
     1441 gctaacgtta tcggctttgg tggtaagatt actggtgaat tgcttatgtg tgatatcatc
     1501 gaagctttca ttcatgctga atacaaacca tctgaagaaa acaagaaatt gattgcgaaa
     1561 attgaacacc ttgaaagtca caatgctcaa caaacagacg caaacttctt tacagaattc
     1621 cttgaaaaat gggatcgcgg agaataccac gactaagagg tgacctatga ttttaacagt
     1681 cacaatgaac ccatccattg atatttccta tcccttggat gagttgaaga ttgatactgt
     1741 caatcgtgtg gtggatgtaa ccaaaacggc tggtggtaag ggacttaatg ttacccgagt
     1801 actttcagaa tttggtgatt ctgttcttgc tactggttta gtgggtggca aacttggtga
     1861 gtttttggtt gaacatatcg atgatcaagt aaagaaagat ttcttttcta ttcagggaga
     1921 aactcgtaac tgtatcgcta ttctccacgg tgacaaccaa acagaagttc ttgaaaaagg
     1981 tcctgaagta ttggaacagg aaggtcaaga ctttttggaa catttcaaaa aactcttgga
     2041 gtcagttgaa gtagtagcca tctcaggtag tctgccagct ggccttccag ttgattacta
     2101 tgcgagcttg gtagagcttg ctaatcaagc tggcaagcta gtagtcttgg actgctctgg
     2161 tgcagcactt caggcggttc ttgaatcacc ccataaaccg acagtaatca aacccaataa
     2221 tgaggaattg tctcagcttc taggaagaga agtttctgag gatttggagg aattaaaaga
     2281 agtccttcaa gaatctttgt ttacagggat tgaatggatt atcgtttcac ttggtgccaa
     2341 cggtactttt gccaaacatg gtgacacttt ctacaaggta gatattccta gaattcaggt
     2401 ggtaaatcct gttggatctg gagactctac tgtggcagga atttcttcag gacttcttca
     2461 caaagaatcg gatgcaggat tactcatcaa ggcaaatgtc cttggtatgc tcaatgctca
     2521 agaaaaaatg actggtcatg tcaacatggc caactatcaa gctctatatg atcaattaat
     2581 agtaaaagag gtataaaatg gctttaacag aacaaaaacg tgtacgctta gaaaaacttt
     2641 ctgatgaaaa tggtatcatc tcagctcttg catttgacca acgtggtgct ttgaaacgcc
     2701 tcatggctca acaccaaaca gaagaaccaa ctgtggccca aatggaagaa cttaaaatct
     2761 tggtagcaga tgaattgact aaatacgctt catctatgct tcttgaccct gagtatggac
     2821 ttccagcaac taaggctctt gatgaaaaag ctggtcttct ccttgcttat gaaaaaacag
     2881 gttatgacac aacaagcaca aaacgcttgc cagactgctt ggatgtttgg tctgcaaaac
     2941 gtattaaaga agaaggtgca gatgcagtta aattcttgct ttactatgat gtagatagct
     3001 cagacgaact caatcaagaa aaacaagcct acatcgaacg catcggttct gagtgtgtgg
     3061 ctgaagatat cccattcttc cttgaaatcc ttgcttacga tgaaaaaatt gcggacgcag
     3121 gttctgtaga atacgctaaa gtaaaaccac acaaagttat cggtgctatg aaagtctttt
     3181 cagacccacg ttttaacatt gatgtcttga aagttgaagt tcctgttaac attaaatatg
     3241 ttgaaggctt cgctgagggt gaagtggttt acacacgtga agaagcagca gccttcttca
     3301 aagcgcaaga tgaagcaacg aacttgccat acatctactt gagtgctggt gtatcagcta
     3361 aactcttcca agatactctt gtatttgctc atgaatcagg tgcaaacttt aacggagttc
     3421 tttgtggtcg tgctacatgg gcagggtcag ttgaagctta catcaaagat ggtgaagcag
     3481 cagctcgcga atggcttcgc acaactggat ttgaaaacat tgatgagctc aataaagttc
     3541 ttcaaacaac agcgacttca tggaaagaac gtgtgtaaga aagtcctcct agtttaggaa
     3601 catgaatcta aaaaaattta aaaaaagttg tatgtaaagg tttacaaaat aacttacttg
     3661 tgctatactt aaatcacaag ttaatacaag gtgagtgtta ctaagtaata ttaggcatga
     3721 tcacaggtga attagaaatc agctgatttt ctagttcatt tgtggtcatt ttttgtactc
     3781 atataccttt aagatataaa aggaggttga catgtatcga attctaaatc caatgaatca
     3841 caatgtctcg cttgtcagaa atgataaggg agaagaggtg attgtaattg gtaaggggat
     3901 tgcattcgga aagaagaagg gggatttgat tgctgaaaat catgttgaga aaatctttcg
     3961 gatgaagacc gaagagtcca gagaaaactt tatggctctt ctcaaagatg ttccgcttga
     4021 ttttatcaca gtgacctatg aaatcattga taagctatca aagaaatatc attatccgat
     4081 tcaagagtat ctctatgtaa ccttgacaga tcatatttac tgttcttatc aagctctaat
     4141 tcaaggaagg tacaaggata gtaatctgcc agatatttct gctaagtatc ctgtcgcttt
     4201 tcaaatcgca aatgaagctt ttgaaattta ccgtcagaag ctagcagatc attttcctga
     4261 ggacgaaatt attcggattg cttatcattt cattaatgct gaaggtgaaa atgaagtgga
     4321 acttgtggag tcgattgata agaggaaaga aattctcagg aatgttgaag aagttttaac
     4381 ggactatgca attcaacgaa ctaaaaagaa taaccatttc tatgatcgct ttatgatcca
     4441 tttgaattat ttcttggatt atttagacag atctagagat gataaccaat cacttctgga
     4501 tatggaagat catattaaac aatcctatcc aaaagccttc gagattggtt ccaagatcta
     4561 tgatgtgatt acgcaacata cgggtcttga tttgtataaa agtgaacgag tttatctagt
     4621 tctacatatc caacgtttat tgtcataaaa atttatttaa aactatataa ggagaattct
     4681 atcatgaata gagaagaagt aacattgtta ggttttgaaa tcgtagccta tgctggcgat
     4741 gctcgttcaa aactattgga agccttgaag gctgctgaag ctggtgattt tgaaaaagcg
     4801 gacgctctgg tagaggaagc tggtagctgt attgcagagg ctcaccacgc gcaaacaagt
     4861 ctattgacta aggaagcttc tggtgaggac ttagcgtata gtgtgaccat gatgcatggt
     4921 caagatcact tgatgacaac tatcttgtta aaagacctaa tgcaccattt aattgaactt
     4981 tacaagagag gagttaaata aaatggataa gttaataatt tttattgaga aaggaaagcc
     5041 tttctttgag aaattatcga gaaatatata cttaagagcg ataaaagatg gttttatttc
     5101 cagtatgcca gcagtattat tctcaagtat ttttatacta atagctgctg tgcccaatat
     5161 ttttgggttt aaatggtctg atgaacagtt agcttttatt ttgaaacctt acaactactc
     5221 aatggggatt ttagctctct tagtagctgg gacaactgca aaatcgttaa cagattcagt
     5281 taatacacgt agtatggaga aaaccaacca aatcaactac atgtcaactt ttttagcagc
     5341 tgttgttgga ttgttaatac tggcagctga tccaattgaa ggtggatttg ctaatggtct
     5401 tttaggtact agaggattac ttactgcatt tttggcagct tttattacag taaatatcta
     5461 taaagtatgt attaaaaata atgtaaccat tagacttcct gaagaggttc caccaaatat
     5521 tgcacaagtt tttaaagatg ttattccgtt tgccttatct gttctttcaa tatatggatt
     5581 ggatttaatt gttagaaata tttttggtac aaatgtagca gaatctgttg gtaaaatatt
     5641 agcccctcta ttttcagcta ctgatggtta tatcggttta gctattgtat ttggtgctta
     5701 tgctttcttt tggtttgttg gaattcatgg gccatctgtt gtagaacctt taattgtagc
     5761 tatcagttat gcaaatatag aagctaatgt tcagcttgtg caagctggta tgcacgcaga
     5821 taaaatttta aatccagtta ctcaaacttt tgttgtaaca atgggtggta ctggtgcaac
     5881 actagtagtt ccatttatgt ttatgtggtt atgtaaatca aaaagaaata gaattgtcgg
     5941 acgtgcgtct gtagttccta ctttctttgg cgtaaatgaa ccaatcctat ttggtgctcc
     6001 aattgtttta aatcctatct tctttattcc gtttgttact gctcctatta tcaatgtttg
     6061 gattatgaaa ttttttgtag atgttctaca aatgaatagt ttcagtatta ttttaccttg
     6121 gacaacacct gctccaattg gtattgttat gggaacggcg ctggctccat tgtcattcgt
     6181 cttggctata actttaatca ttatcgacac tttaatctat tatccatttg ttaaagttta
     6241 tgaccatcaa attttagaag aagaacgttc aggtaagtct aatgatgaat tgaaagaaaa
     6301 agttgctgca aacttcaaca ctgcaaaagc ggatgctatt cttgaaaaag cgggtgtcga
     6361 tgcagcacaa aataccatca ctgaagaaac aaatgtcctc gttctctgtg caggtggagg
     6421 aacaagtggt ctccttgcaa atgctttgaa taaggcagca gcagaataca atgtccctgt
     6481 gaaagcagca gcaggcggct atggtgctca ccgtgaaatg ttaccagagt ttgatcttgt
     6541 tatccttgcc cctcaagttg cttcaaactt tgaagatatg aaagcagaaa cagataagct
     6601 cggtattaaa ctagcgaaaa cagaaggcgc tcaatacatc aaattaactc gtgatggaaa
     6661 aggtgctctt gcattcgtac aagcgcaatt cgattaaggc tagagactct gaaatagtct
     6721 cctatcgtta cggaaatcgc tatggcgaat ttcctattat taattcgtcg gtaaaaagat
     6781 atcgttttta cctcctcatg tcacaattcg gtgacttggt acaagaagtg agatggagaa
     6841 ggatggctca ctgactcctc tcctctcact tttactttat ttaaatcaag aaataggtga
     6901 aaaaaatgac aaaaacactt ccaaaagact ttatttttgg tggcgcaaca gctgcctatc
     6961 aagcagaagg tgctacacat actgatggta aaggaccagt agcgtgggat aaatatcttg
     7021 aagataacta ctggtacact gcagaaccag ccagtgattt ttacaatcga tatccagttg
     7081 acctcaagct agcagaagag tatggtgtca atggtattcg aatttctatt gcttggtcac
     7141 gtattttccc gactggttac ggccaagtaa atgctaaagg tgttgagttt tatcataatt
     7201 tatttgcaga gtgtcacaaa cgtcatgttg agccctttgt aactcttcat cactttgaca
     7261 cgccagaagc tctccactca aatggagact tcttaaaccg tgaaaatatc gaacattttg
     7321 tagactacgc tgccttctgt tttgaagaat ttccagaagt aaactattgg acaaccttta
     7381 atgaaattgg gccaattggt gatggtcaat acttggttgg gaaattccct ccaggtattc
     7441 agtacgacct tgccaaagtc ttccaatcgc accacaatat gatggtgtct catgcgcgtg
     7501 cagttaagct atataaagat aaaggctata aaggcgaaat tggtgttgtt cacgctctgc
     7561 caactaagta tcctttagat cctaaaaatc cgtcagatgt tcgtgcagct gagttggaag
     7621 atattattca caataaattt atcttggatg caacttatct aggtcgctat tcagctgaaa
     7681 cgatggaagg tgtcaaccat atcttatcag tcaatggtgg tagcttggat cttcgtgaag
     7741 aagattttac agcattagaa gcagcaaaag acttgaatga tttccttgga atcaactact
     7801 atatgagtga ctggatggaa gcctttgatg gagaaactga aattatccat aatggtaagg
     7861 gtgagaaagg aagttctaaa taccaaatca aaggtgttgg tcgtcgtgta gctcctgatt
     7921 atgtaccacg tacggattgg gattggatta tctaccctca aggtttatat gaccaaatta
     7981 tgcgtgtgaa gaaagattat cctaactaca agaagattta catcactgaa aatggtctcg
     8041 gctataaaga tgagttcgtc gataacactg tttatgatga tggacgtatt gattatgtga
     8101 aacaacactt ggaggtcttg tctgatgcga ttgcagatgg agcgaatgta aaaggttact
     8161 tcatttggtc attgatggac gtcttttcat ggtcaaatgg ttatgaaaaa cgttacggtc
     8221 tcttctatgt agactttgaa actcaagaac gttatccgaa gaaatcagct cactggtaca
     8281 agaaagtagc ggaaactcag attatagact agtagaatta gtcattagat atagaatttt
     8341 agtgagtcaa aaagatgttc aaagatttta tccaatctat ttatgaaaaa gtttatatta
     8401 taaatttcga aaaatgctct caaataccgt gtttgacgag tgaagaattg aaaagtctat
     8461 ttttaaattt tatcaatcct gaagaatggg atactatctc ctttgattca gattttatgc
     8521 catttcaaca atcgtaacca atttctcaaa aaagttaaat cttatattta gtactctgca
     8581 aaactcttat ctaatcacgt tgcttatact caatgaaaat caaagagcaa ctttaaacta
     8641 ggaagcgagt cgcagatttc tcaatgcata gctttgagga attgggcaaa aagtctttga
     8701 tatagaaaaa gcatagtatc aggtgtttca acacctgata ctatgctttt tattgtggga
     8761 agatttactt tttttcttct gaaattgagt tgttacccag gctctttcag tttattaagg
     8821 cttgatgact ttaatgtgtt tagatagctt aaaaaggatt gaatcactta gtttagaatc
     8881 tgaaacaata gtatcaagat ttgatacatt ataaaaagta taaaaatcaa acttattgaa
     8941 cttactatga tctgcgagta aatatttttt attagaatta tttaaagcga tgcgttgagc
     9001 ctctccctct tcctcgctaa aagtagctag agctccgttt tgaataccat tacagctaac
     9061 gaaagcttta gaaaattgga gattagagag attttgtagg gtcaatgtgc caacaaaagc
     9121 acctgtaata tcgcgataat ttccacctat caaaatcaaa tctgttaatt ttcgttcgct
     9181 taaaatcaga aaaacaggta gactgttggt tacgacgcgg atattgtcaa taggcaactc
     9241 acgcgcaaaa aactctaatg ttgttcctgg tccaatgaaa atagtttctc tttcttctac
     9301 tagactgcct gcaaaatggg ctatttcttg tttttctgcc gtttggaggg cttgtttttc
     9361 aatatttgat cgctcattag tcaaaaggga gttggttcga agtttttcag ctccaccatg
     9421 cacacgaatc agcaaatctt tatcagctaa ttcctgtaaa tagcgccttg cagtcatatc
     9481 tgaaacggct atttcgtcca taatctgttt aactgttatg gttcctttac tatttactat
     9541 ctctaaaatt ttggctaatt tttcttgttt gagcatatta tcacctcgtt tcctactact
     9601 atcttaccat aaacaaactc atcattcaaa tacaaaaaca acaaaatgaa acaaaaacaa
     9661 aaatatcgaa gtttgttttc aaaactttcg atatttttgt tgggttataa ctttgatgtt
     9721 tctagtttac tttttgatga ttgagagtga tggagaatta gtctaaaccg tagttatagt
     9781 catcgtcttg catggcttca acttcgccaa gaaggtaacc atttccgact tgagagaaga
     9841 agtcatggtt ggaagttcct gttgaaatac cgttcataac gattgggttg acatcttcag
     9901 ctgaatctgg gaaaagtgga tcttgtccca tgttcatgag agctttattg gcattgtagc
     9961 gaaggaaggt tttaacctct tcagtccaac caacaccgtc ataaagactc tctgtgtagc
    10021 cttcttcatt ttcataaaga gtatagagta ggtcgtacat ccattctttg agtttttctt
    10081 gctcttcttc aggcaattca ttgaaaccaa gttggaattt gtaaccaatg taggttccgt
    10141 gaacagactc gtcacgaata atcaatttaa tgatttctgc aacgttggct agtttgttgt
    10201 taccgagata gtagagggga gtgaagaaac cagagtagaa gaggaaggtt tcgaggaaga
    10261 cgctggcaac tttcttttca agtgggctgc cgtttaggta gatttcgttg acaatctcag
    10321 ccttcttttg taggtaagga ttggtattgg tccattcgaa aatttcttca atctcagcct
    10381 tagtattcaa ggtagaaaag attgatgagt aagatttagc gtggacagat tccataaatt
    10441 ggatgttatt gaaaacagct tcctcatgtg gtgtacggat gtctgcgcga agggcttgaa
    10501 ccccagtttc agattgcata gtgtcaagaa gggttaaacc accaaaaact tttccgacca
    10561 agtctttctc tttgttagat agctttctcc agtcatccaa gtcgtttgat aagggaatac
    10621 gtgtatcgag ccaaaattgc tccgtcagtt tttcccaagt tgatttgtcg atgacatctt
    10681 cgatggcatt ccagttaatg gctttgtagt aagtttccat ttaaaatctc tttctgtgtt
    10741 tagtattgcg aactcacaat tatttctact ttaccataat tctataggag tatcgcacaa
    10801 aaagtcggaa gcccgacttt taaaatgtta cataaattat gttatgacat agtagatttg
    10861 attttatcag tgctgcttag ggaaaaataa tgtttctatg ctagaaacta aatcacacag
    10921 ctttcacatt ggttggcgcc gacttctcca ccgtcatctg taaaggtacg gacgtagtag
    10981 atagacttga ttcccttgtt aaaggcatag ttacgaagga tggacaagtc acgtgtcgtt
    11041 tgtttatttt ccctcttcca ttcgtaaagg ccttttggaa tgtcactacg catgaagagg
    11101 gtgagtgaaa gtccttgatc cacgtgttca gtcgcagcag cgtaaacatc gatgacttta
    11161 cgcatatcca tatcgtaggc agaagtgtag taaggaatgg tttctgtaga caagccagca
    11221 gcagggtagt agattttacc aattttcttc tcttggcgtt cttcgatacg ttgcgtaatc
    11281 gggtggatag aagcagaaac gtcgttgata tagctgatag aaccatttgg cgctacagca
    11341 aggcgatttt ggtggtaaag accatcttct tgaaccttgt cgcgaagttc agcccaatca
    11401 gcaacaccag ggataaagac atttttgaag agttctttaa cacggtctga tgttggaaca
    11461 aattcaccag ttacatactt gtcaaagtaa cttccgttag catagtctga tttttcaaag
    11521 ttgtggaagg taataccacg ttcacgcgca atattgtttg actctaccaa ggtccagtag
    11581 ttcataagca taaagtagat gcttgtaaat tcaacagact caggtgaacc atattcaatg
    11641 agttgttggg caaggtagct gtgcagtccc atggcaccga gaccaaaggt gtgggcttgg
    11701 ctatttccat ggtcaatcgt tggtacagct acgatatgtg aactatctgt aacgaaagta
    11761 agggcacgaa ccatagcacg gatagaacga ccaaaatcag gtgaagtcat catgttaacc
    11821 acgttggttg aacccaggtt acatgaaaca tctgttccca tttgaaggaa ttcttgagca
    11881 tcgttgatca agcttggttc ttgaacttga agaatctcag aacacaagtt actcatgata
    11941 atctttccat caacaggatt tgcacggtta gccgtatcga tgttgactac ataaggatag
    12001 ccagactctt gttgcaattt agagatttca gtttccaaat cccgcgcctt gatttttgtc
    12061 ttgcgaatat ttggatttgc gaccaattca tcgtattttt cagtaatgtc gatgtaattg
    12121 aatggcacac cgtattcttt ttctacagag taagggctga agaggtacat ttcttcattt
    12181 ttacgagcca attcgtagaa tttatcaggt actacaacac caagtgatag agtcttgaca
    12241 cgtacttttt catcagcgtt ttctttctta gttgaaagga aagcgatgat atctgggtga
    12301 aagacgttga ggtagacaac accggcacct tgacgttgcc ccaattggtt ggagtaagag
    12361 aagctgtctt caaaaagctt cataacagga acgacacctg aagcagctcc ttcatagcct
    12421 ttgataggtg caccagcttc acgaaggttg ctgagggtaa ttcccacacc accaccaata
    12481 cgtgaaagtt gaagagctga gttgatagaa cgtccgatag agttcatatc atccgtcact
    12541 tggattagga aacaagatac caactctcca cggcgagcac gtccagcatt caagaaggaa
    12601 ggagtagcag gttggtagcg ttggtggatg atttcattgg caatatcgat tgcaacagct
    12661 tcattcccat cagcgaaata aagggcgttg aagaagacac ggtcttccat attttcaaga
    12721 tagtattcac cgtcattagt ctttaaggca tattgattgt aaaatttata agctgccatg
    12781 aatgacttga attggaagtt ttggtctttg ataaattgag ctaattcttc caagaactct
    12841 ggacggtatt tcttgataaa ggctgtttcg atgtagttgt gttcaatgag gtaattgatt
    12901 ttgtctttga ttgaatcaaa aaccatagtg tttggaacta cattttcttt aaagaaagca
    12961 tccaaggctt ccttgtcttt atgaagcatg atttgtccat taacaggacg gttaatttcg
    13021 ttattaagac ggaagtaagt cacgtcttca agatgtttta atcccataaa atttccctta
    13081 tctaattaca aaagaaaggc ttctaagtta gccctaaaag cagtttcttc tggatgatgt
    13141 actaagatta tgctaattgt ttcagttttc ctggttggaa acctgaaaag acttcagttg
    13201 gtgtttggat aacaggagct gcgctaaaac cgagctcttt aacttgatcg acgtactcag
    13261 gttgctcatc aagattgatt tcacgataag agacattatt actgtccaag aaacgcttgg
    13321 tcattttaca ttggacacaa ttgtttttag aataaacggt taccattgtg taactcctct
    13381 tcaaaattta atactatctt agtatatcag aaaataaaat tttgtcaatg atttgaacta
    13441 aatatagtgg tgttcttttg ttgtttttat atataaacac aatatatagt gtttgtattg
    13501 tgaaatagca atgattatcc tataaattgt ttttaaagaa actatatcct gtgttttgtt
    13561 atctaggata gaagattttc agcaagttat ctgaaaggaa attgaaggaa aatccagaaa
    13621 atgcttgaaa aaaatcctag aagatggtat aatactaaat tgtaagggtt atcacatata
    13681 actcaaaaaa agaaagaaca aaaggagagt caaactatgg cttctaaaga tttccacgta
    13741 gtggcagaaa caggtattca cgcacgtcca gcaacattgt tggtacaaac tgctagcaaa
    13801 tttgcttcag atatcactct tgagtacaaa ggtaaatcag ttaaccttaa atcaattatg
    13861 ggtgttatga gtcttggtgt tggccaaggt gctgacgtaa ctatctcagc tgaaggtgca
    13921 gatgcagatg acgctatcgc tgcaatctca gaaacaatgg aaaaagaagg attggcataa
    13981 gggaaatgac agaaatgctt aaaggaatcg cagcatctga cggtgttgca gttgcaaaag
    14041 catatctact cgttcagccg gatttgtcat ttgagactat tacagtcgaa gatacaaacg
    14101 cagaagaagc tcgccttgat gccgctctac aggcatcaca agacgagctt tctgttattc
    14161 gcgagaaagc agtaggtacg ctcggtgaag aagcagctca agtttttgat gctcacttaa
    14221 tggttcttgc tgacccagaa atgatcagcc aaatcaagga aactatccgt gcgaagaaag
    14281 tgaatgcaga agcaggtctg aaagaagtta cagatatgtt tatcactatc tttgaaggca
    14341 tggaagacaa cccatacatg caagaacgcg cagcggatat ccgcgacgtg acaaaacgtg
    14401 tattggcaaa ccttcttggt aaaaaattgc caaacccagc ttctattaat gaagaagtga
    14461 ttgtgattgc gcatgacttg acaccatctg atacagctca attggacaaa aactttgtaa
    14521 aagcttttgt aaccaacatt ggtggacgta caagccactc agctatcatg gcacgtacac
    14581 ttgaaattgc tgctgtatta ggtacaaata acatcactga aatcgttaaa gacggtgaca
    14641 tccttgctgt taacgggatc actggagaag tgattatcaa cccaacagat gaacaagcgg
    14701 cagaatttaa agcagctggt gaagcctatg cgaaacaaaa agctgaatgg gcacttttga
    14761 aagatgctca aacagtgact gctgacggta aacacttcga gttggctgcc aatattggta
    14821 ctccaaaaga cgttgaaggt gttaacaaca acggtgcaga agctgttgga ctttaccgta
    14881 cagagttctt gtacatggat tctcaagact tcccaactga agatgagcag tatgaagcat
    14941 acaaggctgt tcttgaagga atgaacggta aacctgttgt cgttcgtaca atggatatcg
    15001 gtggagataa ggaacttcct tacttcgata tgcctcacga aatgaaccca ttccttggat
    15061 tccgtgctct tcgtatctct atctctgaga ctggagatgc tatgttccgc acacaaatcc
    15121 gtgctcttct tcgtgcgtct gttcacggtc aattgcgtat catgttccca atggttgcgc
    15181 tcttgaaaga attccgtgca gcgaaagcag tctttgatga agaaaaagca aaccttcttg
    15241 ctgaaggtgt tgcagttgcg gataacatcc aagttggtat catgatcgag attcctgcag
    15301 cggctatgct tgcagaccaa tttgctaaag aagttgactt cttctcaatt ggtacaaacg
    15361 acttgatcca atatacaatg gcagcagacc gtatgaacga acaagtttca tacctttacc
    15421 aaccatacaa cccatcaatc ctacgcttga ttaacaatgt gatcaaagca gctcacgctg
    15481 aaggtaaatg ggctggtatg tgtggtgaga tggctggtga ccaacaagct gttccacttc
    15541 ttgtcggaat gggcttggat gagttctcta tgtcagcaac atctgtactt cgtacacgca
    15601 gcttgatgaa gaaactcgac acagctaaga tggaagagta cgcaaaccgt gcccttacag
    15661 aatgctcaac aatggaagaa gttcttgaac ttcaaaaaga atacgttaat tttgattaat
    15721 cgaaaagtcc ctgcaactca gttacaggga ctttttttga tattttaaaa agaattttca
    15781 agaaaatctt tcttataaaa agtccaacct tgaaaaagta gtggtcagaa caaaaaatac
    15841 ttaaatggtt cataaaattc ttgacaagtt ggagatttag gagtaaacta ttaaccagtt
    15901 aagtaataga gaggagtttc tgcaatttag aaatgaattg caactagaaa tatcaaatag
    15961 aaagagagtt tcgatgaaaa ttaataagaa ataccttgtt ggttctgcgg cagctttgat
    16021 tttaagtgtt tgttcttacg agttgggact gtatcaagct agaacggtta a
//
LOCUS       DAVAZT010000051        14432 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVAZT010000051 DAVAZT010000000
VERSION     DAVAZT010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14432
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.051"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..2288)
                     /locus_tag="VQT45_001640"
     CDS             complement(<1..2288)
                     /locus_tag="VQT45_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec-dependent serine-rich glycoprotein
                     adhesin"
                     /protein_id="HET2359933.1"
                     /translation="MFKVMRGGVDTTQVMTETVEDKVSHSITGLDILKGIVAAGTVIS
                     GTVATQTKVFTNESAVLEKTVEKTDALATNDTVVLGTISTSNSASSTSLSASESASTS
                     ASESASTSASTSASTSASESASTSASTSISASSTVVGSQTAAATEATAKKVEEDRKKP
                     ASDYAASVTNVNLQSYAKRRKRSVDSIEQLLASIKAAVFSGNTIVNGAPAINASLNIA
                     KSETKVYTGTGLDSVYHVPIYYKLTVTNDGSKLTFTYTVTYVDPTTRALGNLSKMGHG
                     YSIYNTGTSIQTMLTLGSDLGTPSDVKNYITDKDGVLVRSYNTSTMTTWGSGYTWGNG
                     AQMNGFFAKQGYGLTSSWTVPITGTDTSFTFTPYAAKTDNIRTNYFKGRGKVVESSTT
                     SQSLSQSKSLSVSASQSASASASTSASESASTSASASASTSASASASTSASASASTSA
                     SASASTSASESASTSASASASTSASASASTSASASASTSASASASTSASASASTSASA
                     SASTSASASASTSASESASTSASESASTSASASASTSASASASTSASASASTSASASA
                     STSASASASTSASASASTSASESASTSASASASTSASASASTSASASASTSASESAST
                     SASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSA
                     SASASTSASASASTSASESASTSASASASTSASASSSTSASASASTSASASASTSASA
                     SASTSASASASTSASESASTSAS"
     gene            complement(2286..2399)
                     /locus_tag="VQT45_001641"
                     /pseudo
     CDS             complement(2286..2399)
                     /locus_tag="VQT45_001641"
                     /inference="COORDINATES: protein motif:HMM:TIGR03715.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
     gene            complement(2637..3098)
                     /locus_tag="VQT45_001642"
     CDS             complement(2637..3098)
                     /locus_tag="VQT45_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000514209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2359934.1"
                     /translation="MGKERRKQGNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIA
                     ARFDCALPSVWAVLKQIKVILKKTTSFREQKPEKVSEFLDILDNLKDLPVLYIDETGI
                     NRYLYRPYAGAPRGEKVYDKISGRRFERTNEVEQKLNGSFLIRYIDSQIRE"
     gene            complement(3065..3208)
                     /locus_tag="VQT45_001643"
     CDS             complement(3065..3208)
                     /locus_tag="VQT45_001643"
                     /inference="COORDINATES: protein motif:HMM:NF013842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2359935.1"
                     /translation="MAYSTDFKQGALDSIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KGT"
     gene            3477..3857
                     /locus_tag="VQT45_001644"
     CDS             3477..3857
                     /locus_tag="VQT45_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET2359936.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            3956..4177
                     /locus_tag="VQT45_001645"
     CDS             3956..4177
                     /locus_tag="VQT45_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET2359937.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            4194..4508
                     /gene="trxA"
                     /locus_tag="VQT45_001646"
     CDS             4194..4508
                     /gene="trxA"
                     /locus_tag="VQT45_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET2359938.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            4815..5348
                     /gene="queF"
                     /locus_tag="VQT45_001647"
     CDS             4815..5348
                     /gene="queF"
                     /locus_tag="VQT45_001647"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HET2359939.1"
                     /translation="MKHQSALVVFSGGQDSTTCLFWTMQHYETVEAVTFAYGQHHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(5602..6270)
                     /locus_tag="VQT45_001648"
     CDS             complement(5602..6270)
                     /locus_tag="VQT45_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HET2359940.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLSN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(6381..6935)
                     /locus_tag="VQT45_001649"
     CDS             complement(6381..6935)
                     /locus_tag="VQT45_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HET2359941.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRNVLLNQGL
                     HYLSKEKDTRGFSSQYGWVHAFAHGADLLTEVVCHPGFPKNRVHEVFEILGQLFKRMS
                     IRFTDDEDWRLARVIYEPILQGKLAQEQVASWIKTVDFPIEEREDFYKFSNFRSCLVE
                     VYVQLDQRNSLQDELKEAIQSFQY"
     gene            complement(7181..8977)
                     /gene="pepF"
                     /locus_tag="VQT45_001650"
     CDS             complement(7181..8977)
                     /gene="pepF"
                     /locus_tag="VQT45_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET2359942.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYGFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDATLTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKHSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIISYSAELGE"
     gene            complement(8988..9731)
                     /locus_tag="VQT45_001651"
     CDS             complement(8988..9731)
                     /locus_tag="VQT45_001651"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HET2359943.1"
                     /translation="MQQYFVKGSAVSPVTIEDRETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFITQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNVVPSIHLFENKADFLAQLDQ
                     FDRILVAYEEAAKEGEAAALIKAVTGLEKGAKLLFIFGPEGGLSPAEIENFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLVELEK"
     gene            complement(9733..10683)
                     /locus_tag="VQT45_001652"
     CDS             complement(9733..10683)
                     /locus_tag="VQT45_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HET2359944.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYMGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDMTVVEADLQARLAELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNTG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKW
                     DMVRQSAESAGFFLETHMIQGEWNACVFKKTKDISGVIGG"
     gene            complement(10821..11249)
                     /locus_tag="VQT45_001653"
     CDS             complement(10821..11249)
                     /locus_tag="VQT45_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2359945.1"
                     /translation="MELEISDFQGCKIALFCGDKLLTILRDDKDDIPCPNMWELPGGG
                     REGDESPFECARREVYEELGIHLDEDCLLWSKIYPSVIFKGKKSVFMVGQLRQEQFDN
                     IIFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            complement(11230..12318)
                     /locus_tag="VQT45_001654"
     CDS             complement(11230..12318)
                     /locus_tag="VQT45_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HET2359946.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            complement(12337..12807)
                     /locus_tag="VQT45_001655"
     CDS             complement(12337..12807)
                     /locus_tag="VQT45_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HET2359947.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     VLFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            complement(13098..13550)
                     /locus_tag="VQT45_001656"
     CDS             complement(13098..13550)
                     /locus_tag="VQT45_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HET2359948.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            complement(13587..13766)
                     /locus_tag="VQT45_001657"
     CDS             complement(13587..13766)
                     /locus_tag="VQT45_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HET2359949.1"
                     /translation="MPMTQKEMVKLFTAHGWIKTRGGKGSHIKIEKQGERPITILHGE
                     LNKYTERGIGKQAGL"
     gene            complement(13903..14082)
                     /locus_tag="VQT45_001658"
     CDS             complement(13903..14082)
                     /locus_tag="VQT45_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359950.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSGPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            complement(14247..>14432)
                     /locus_tag="VQT45_001659"
     CDS             complement(14247..>14432)
                     /locus_tag="VQT45_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359951.1"
                     /translation="IFTKQIRHWILSDQVISGKRKLFFREDTPKEILDLYENIKSKLD
                     FAYQEVHSNNGLKKYEK"
BASE COUNT         4196 a         3287 c         2765 g         4184 t
ORIGIN      
        1 gacgcactcg ttgaggctga ctcagacgca ctcgttgagg ctgaagctga cgcactcgtt
       61 gatgctgaag ccgaggcact ggttgacgct gaagctgagg cgcttgttga tgctgaggct
      121 gatgcgcttg tgcttgatga agctgaggca cttgttgatg ctgaggctga cgcactcgtt
      181 gatgcagatt cagacgcact tgtgcttgct gaggctgacg cactggttga tgcggaagct
      241 gaggcgcttg tgcttgctga agccgacgca ctcgttgagg ctgaagctga agcgcttgtc
      301 gatgctgagg ctgacgcact tgtcgacgct gaagctgaag cactggttga cgctgaagct
      361 gaggcactgg ttgacgctga agctgacgcg ctggttgagg ctgaggctga ggcgctagta
      421 cttgctgact ctgatgcact ggtacttgct gaggctgacg cacttgtgct tgctgaagcg
      481 gacgcactcg ttgatgctga agctgaagca ctggtacttg ctgactctga tgcactggta
      541 cttgctgagg ctgacgcact tgtgcttgct gaagccgatg cactcgttga tgcggaagct
      601 gatgcacttg ttgatgcgga agctgatgca ctcgttgatg ctgaagctga ggcgctagta
      661 cttgctgagg ctgaggcact ggttgatgcc gattcagatg cactggttga ggccgattca
      721 gacgctgagg tacttgctga agctgacgca ctggttgacg ctgaagctga tgcactggtt
      781 gacgctgagg ccgaagcact ggtacttgct gaagccgacg cactggtgct tgctgaagcc
      841 gaggcgctag tgcttgctga agccgacgca ctcgttgatg cggaagctga cgcactcgtt
      901 gatgcagatt cagacgctga ggtacttgct gaagctgagg cactcgttga tgcggaagct
      961 gacgcactcg ttgatgctga ggctgaggca cttgtacttg ctgaggctga tgcgctggtt
     1021 gaggccgatt cagaagctga ggtgcttgct gaggctgagg cgctttgact agcacttact
     1081 gagagtgact tagactgtga aagtgactga ctggtcgtgc tagattcaac tacctttcct
     1141 ctacccttga agtagttagt tctaatgtta tctgttttag cagcgtaagg ggtaaatgta
     1201 aaggatgtat ccgttccagt aattggtaca gtccaagatg atgttaatcc atatccttgc
     1261 ttagcaaaga aaccattcat ttgggcacca tttccccaag tatacccact accccacgtc
     1321 gtcattgtag atgtattata ggatcgaacc agtacaccat ctttgtcagt aatgtagttc
     1381 tttacatctg aaggggtacc aagatcactg ccaagggtta acattgtttg tattgaagta
     1441 cctgtattat agatagaata cccatgaccc atctttgaaa gattaccaag agcccttgtg
     1501 gtaggatcta catacgtaac cgtataggta aaggtcagtt ttgaaccatc atttgtcact
     1561 gtcaatttat agtaaattgg aacatgatat accgaatcta aacctgtacc tgtataaact
     1621 tttgtctcac ttttagcaat gtttagactt gcattaattg caggggcgcc atttacaatc
     1681 gtattgccag aaaaaacagc agcttttata gaagccagca attgctcgat ggaatccact
     1741 gaacgcttgc gtcgcttagc ataagattgg agattgacat ttgtaactga tgctgcataa
     1801 tcactagctg gtttcttacg atcttcttcg accttcttag cagttgcttc tgtagcggca
     1861 gctgtttgtg atcctaccac agtagatgat gcagagatac ttgtcgaagc cgatgtactt
     1921 gctgattctg atgcacttgt actcgctgag gtcgaagcgc tggttgaggc tgactcagat
     1981 gcagatgtac ttgccgactc tgaagctgac aaactagttg aactcgctga attacttgta
     2041 gatatcgtac ctagaactac tgtatcattt gttgccaaag catccgtttt ctctacagtt
     2101 ttttcaagta ctgccgactc atttgtaaat accttcgttt gagttgcaac ggttccactt
     2161 atgacagttc ccgcagcaac tattcccttg aggatatcaa gcccagtaat tgaatgactt
     2221 actttatctt ctaccgtttc ggtcatgacc tgagtagtat caacaccacc acgcatgacc
     2281 ttaaacaagc caaaaagaga agtcgaggcc cgtagccaat gcttccctga tttgattaat
     2341 ttgaaccgag ttactcggtc tgtttctcta tattcaccct tctgacgtct aaaaaatatt
     2401 ttgaaatttc ctttcgagta ttattttcat gtatggatat aaataaatta ccatactata
     2461 attatagaat agggaaccca aaatagcaag aaacttgagg tatttttgct aaaaaaaaaa
     2521 agcattttac tattttatat atatattata agataagttt tttataaaga cacgcaaatg
     2581 agtataaatc agctaatttt tggtttatat tcctattttt atgcataatt attctttcat
     2641 tctctaattt gtgaatcaat atatctgatt agaaaactac cattgagttt ttgctccacc
     2701 tcattagtcc gctcaaaacg ccgtccgcta atcttgtcat agactttctc ccctctagga
     2761 gcccctgcat aaggacgata gaggtagcgg ttgattcccg tttcgtcaat atataggact
     2821 ggtaaatctt ttaggttatc caaaatatca agaaactcag aaactttctc aggcttttgt
     2881 tccctaaaac tggtcgtctt ttttaaaatg accttaatct gctttaaaac tgcccatacg
     2941 gagggcaaag cacaatcaaa acgggccgca atttcccgta aaaaagcgtc tggatgagcc
     3001 tctacaaagg ctttcaattc ttctaaaggg atcttacgct ttttgacgac tcgctttttc
     3061 cgctctaagt tcccttgttt acgtctttct tttcccacgt gaagagagtt ctgacgccaa
     3121 caccaaaaaa cttggctgcc tcgacatgac tgtgcccctc tttgatggaa tctaatgctc
     3181 cttgtttaaa atcagtacta tatgccatag ctttattaga ccatgcttat tttaaactaa
     3241 gcaactatag atagagaaat gaaataaaat ctaaattcga atgtgataag gagttagaaa
     3301 ttgaaacaat aggattcccc cattattcac acaaaaataa aaccactaaa aaacagagct
     3361 tgccagcatt cttgaaaagt agtataatta ttgcatgcgc aatcatcttg tgacgcagag
     3421 actgcccgtt aatggacttt cttctatatt atgactctaa aaagaaagga gacactatga
     3481 cctatttgga aaaatggttt gacttcaatc ggcgtcagaa agaaattgaa agtctcttgg
     3541 aagagaccat tgcccaacag agcgagcaaa gtctgacctt gaaagagttc tacctgctct
     3601 actatctgga cttggctgaa gaaaaatctc tacgccagat tgacctgcca gataaacttc
     3661 atctgagccc gagcgcagtt tctaggatgg tggctcgctt ggaagctaaa aattgcggtc
     3721 tactcagtcg catgtgttgc catcaagata gacgctctag ttttatctgc ctgacaaatg
     3781 atgggcaaaa gacactggcc tcgctacaaa agactgtcga agaaagcttg gaagcaggtt
     3841 tggatttctt gatttaagat gattttaaaa aaagttgcgt gcgcaatcat ttttcttgac
     3901 attctctttt ataaggagta aaataaagtt agcattaaac aaaggagttt taaatatgat
     3961 tgaaattacc tatatagatg ccagcaagaa cgaaagaact gtgactttcg agtcttatga
     4021 agactttgaa cgttcacaac aagcttgcct tatcggcgtc gcagactact accctgtcca
     4081 aaaattaact tacaagggtc ataatttgga ctaccatggg acttatggag atatcttctt
     4141 ctatctcatg aaacaagatt taagccaata taactaaaaa aaggagaaat acaatggcaa
     4201 aagcaattac agatgcaaca ttcgaacaag aaacaaaaga cggtttggtc ttagtagact
     4261 tctgggcaac ttggtgtggt ccatgtcgta tgcaaggtcc aatcttggac aaattgtctg
     4321 aagaactttc agaagatgtc ttgaaaatcg ttaaaatgga cgttgatgaa aatccaaaca
     4381 cagctcgtgc ttttggaatc atgtctattc caactcttct cttcaaaaaa gacggccaag
     4441 ttgtcaaaca agttgcaggt gttcacacag cagaacaaat caaggccatc attgctgaat
     4501 tgagctaatc aaacgagaga ccaagtactt tctttggtct cttttttctt gccctttgcc
     4561 atttttcaaa aaatatgcta gactatagta gattgaaact agaatagtac acctctactt
     4621 ctaaaacatt gttaaaaatc gatttgactg tcctgatcga tttgtcctgt ttttatttca
     4681 ttttactata taagtagaat attacgatgt ttgggatatg ccatcgctaa aaaaaaactc
     4741 gatttggtat tttttagttc cctaatggga gctttttgcg tgctctgaac atttcccatt
     4801 ttggaaggag tactatgaaa catcaatcag ccttggtcgt ctttagtggc ggtcaagatt
     4861 caacaacctg ccttttctgg accatgcaac actatgaaac agtcgaagct gtcacctttg
     4921 cctacggcca acatcatcac ctcgaaattc aaattactag agaaatcgct aaggaacagg
     4981 gcattcgtca ccatatcctc gatatgtctc tgctgggaca aatcactgct cagccagact
     5041 ttgcgacgat tcatatttcc tacattcctg acaagctctg tgtcgagtca aaatccctca
     5101 aactatatct atttagctac cgaaaccacg gagatttcca cgaaaactgt atcaacacca
     5161 tcgggaaaga cttggtcaac ttgctagacc ctcgctattt agaagtctgg ggaaaattca
     5221 ctccgcgcgg tggcatttca atcgacccct actataacta cggtaagcaa ggaactaagt
     5281 atgagggctt ggcagaacaa cgcctcttcc aacacgacct ttatccagag aaaattgaca
     5341 accgctaaag tcatactcaa tgaaaatcaa agagcaaact aggaagttag ccgcaggtta
     5401 ctcaaagcag tgtttgaggt tgtagataaa actgacgaag tcagatcaaa acactgtttt
     5461 gaggttgtgg atagaactga cgtagtcagt aaccatacct acggcaaggt aaagctgacg
     5521 tggtttgaag agattttcga agagtatcat acgaaaaagc cctgttcctc aagatgagga
     5581 gcaaggcttt ttgagtttca attattcttc tgttccaagg aaattttttg caacaagggc
     5641 tgcaagaact ccaccagcga ttggtgcaag gatgaaaatc caaacttgtt gaagggctgc
     5701 gccgcctacc aagacagctg gtgccaagct acgagctggg tttactgaaa gtccagtaat
     5761 cttcaatccg acaagaatca tcgccatcaa tgacaaaccg attaccaaac cagcaatcgc
     5821 gccattgccc ttgctttctg aagtcacagt catgataacc aatacaaaca agaaagttgc
     5881 gatgacttca aacaagaaac caccaaagac agtgacaccg tttgccaagg cattttcacc
     5941 aagactagca gttgacatac ctgaattact caagaggaag aagactgcgc cagaagcgat
     6001 gaaagctcca acaacctgac caaggatgta gtttacaagt tctgaagatg acaaacgttt
     6061 gtttacaaac atagcaatcg aaacagccgg gttcaagtga gcacctgaaa cagttccgat
     6121 tgagtaggct gccaccacga ttgccaaacc aaaggcaaag gcgattccaa ggtgaccaag
     6181 gccatcaaga ccatttccaa aaacaacagc tcctgttcca acgaacacaa gcatgaacgt
     6241 accgattaac tcagcaacaa attttttcat tttctttctc cttttttcaa aaactagata
     6301 ctagtctatc aaaagtagga aagggtttca agaaaattga ttggaaattt tttgaaaatc
     6361 atagaactat tagctaatct ctagtattga aaagactgga tagcttcttt caactcatct
     6421 tgtaaactat ttctctggtc aagttggaca tagacttcca ccagacagga tctaaagttg
     6481 gaaaatttgt aaaaatcctc cctttcttct atcggaaaat caacagtttt tatccaagaa
     6541 gctacttgtt cttgcgctaa cttcccttgt aaaataggtt catagatcac tcttgctaaa
     6601 cgccaatcct catcatctgt aaagcgaatc gacattcttt taaataattg gccaagtatc
     6661 tcaaatactt catgaactct gtttttagga aagcccggat gacaaaccac ctctgtcagt
     6721 aaatcggctc catgtgcaaa agcatgaacc caaccatact gacttgaaaa accccttgta
     6781 tccttttctt ttgaaagata gtgcaagcct tgatttaaaa ggacattacg aatttctgga
     6841 gaaggatttc ccaaatgatc aaacaaccac tggatttctt cctggttata atttggtttt
     6901 tcttctgcta tttttcttag taaatcttga tacatggtca atacctctac atttctagca
     6961 actgttcaaa aaggcagtct taaatgactc aatattgaat tctcaattaa atacaatctg
     7021 atataaaatg acgtaaataa ctatcaatac cagttctaca gtaagttcaa atttaacatc
     7081 acgatcttca acgacatttt tgaaaatagc tacaactaag acaaatagaa tgacgcttaa
     7141 caagcccata aacatcattc taaaaaattt ttctattccc ctactctccc aactcagcac
     7201 tataggagat aatctggtca actgtgtcag acaagaattg gatggtatca cggagtggtt
     7261 tgtctgttga aatatcagca ccgataatca tggctgactc aagtggtgtc ttgctaccac
     7321 ctgatttgag gagattgagc cagtcttcag ctccagtttc agaatgtttt agatgaaggt
     7381 aaccagcagt cgagataact agtcctgctg agtaagtgta actatacaag cccatatagt
     7441 agtgagcttg gcgcatccaa gtcagagttg catcatcgtc aatttcaata gcatctcccc
     7501 agaaatccgt caaaacttcc ttcataatgc tgttgagctt gcttgctcca aaggtctccc
     7561 cttcttcaat caatgtatac accttacgct ggaaggcggc ttccaagagg tgggtgataa
     7621 agttatggaa gtaggtgtct gtcaagcgat gagccagagc gaagcgtttt tgacgtgggt
     7681 cattagactg gttctccaag taatcactga gtagcaattc attgaaggtt gacggtgctt
     7741 caacatagta ggtcgacata tgggcattga agtaactttg atgattgtct gaaaagatga
     7801 attgaccaga atgcccgatt tcatgaatca aggtatagac atcgctcaaa cggcctgtcc
     7861 agctcatgag tacataaggg tgtacgcgat atgggtccgc cgcataacca ccggaatcct
     7921 tgccactgtt agcagcaaag tccacccagc gctcttcttg gtaacgagca acttcctgac
     7981 aatattcttg ccccaaaggt tctaccgact tcatgaccaa atcataggca tcgtcaatag
     8041 tcacttcagg attcagggcg ctgtccaagt ccaatttcca gtctgcaaag gtcatctttt
     8101 caagaccatt taccttggca acatgcttga ggtatctctg agcgactggt gcaaagtcct
     8161 tcatgatgag gtcaatctgg cggtcaaaca tgacacggtc cacttcttgt tcagctagaa
     8221 gatagtcaaa gacagagtcg tatcccttca tatcagccaa gagtttttca gacttgacct
     8281 gagccagata ggctgctgca gccgtatttt ggtgcttacg aagtccctct gagaaggaac
     8341 ggaaggattt ctcacgaacc tcagcatcct catggttttg gtagaaattc tcataggtca
     8401 caaagctgtt tttgtaggtc ttgccatggg cttcaaagtc agccatttca aaatccccag
     8461 ctcgcatctt agtataaatg tcctgcggac tgtagaaaac ttcaccgaga tttgtcaagg
     8521 ccttctccac atctgcccct aagtagtggg cttttttgat tttagcctga cgaatggcag
     8581 ctgttaaatg tggcaattta cccaaacgat ccaagacttc ctcgtctgct gccaccaagg
     8641 catcgtcaaa aaaggtcaag gctacgctgg catctgtttc aaattccatc ccagcttgag
     8701 caatatttgc aaattcgtca ttgctatagt ccgtcgtctg aggcataaaa ccatagttgc
     8761 caatatggct catctgaatg tagatctgtt ccaattccgc aaaggccttc tcgaaatcct
     8821 caaaagtgtg aagattgccc ttgtaatcac ggctaaactg gttgatgtct tcgcgagctt
     8881 tctcgattgc acgcaagaaa tcctcacggt cttggtatag agctgttaaa tcccaaagtt
     8941 ccttctctgg aaattctgaa cggtgttttt gttccatttt cttcctctta tttctctaat
     9001 tctactaaaa cactaagggc tgataaggcg taaagcggtg ctgtttctgc tcttagaatg
     9061 cgagggccaa gtcctgccaa aacagctccc ttagcttcaa aattttcaat ttccgcaggt
     9121 gacagaccac cttctggacc aaagataaag agcaatttgg ctcctttctc gagtccagta
     9181 actgctttta taagagcagc ggcttctcct tctttggccg cctcttcata ggctactaag
     9241 atgcggtcaa actggtcaag ttgggctaga aagtctgctt tattctcgaa aagatggata
     9301 cttggaacaa cattacgctt actttgctct gctgctccaa gagcaatttt ttctagtttt
     9361 tcaacctttt tacccaattt cttgccatcc cacttagcaa cggaccaatc ggcagggaag
     9421 gcccaaatct ggctggcacc tagttccgtc accttttgag tgataaactc caacttatct
     9481 cccttgggaa atccagatgc gatggtcact tggactggta gttccacatt gtcatttaat
     9541 tcttggacca actcaaactg acgattttcc atatccagca cgcgcgccaa gcgcttgatg
     9601 ccatcatcaa agactaaggt aacctcatcc tcttctttca agcgcataac ctgaaacata
     9661 tgcttgctgg tttccctgtc ctcgatggtg acaggagaga ctgcactccc cttgacaaaa
     9721 tactgttgca tgctagcctc caatcacacc tgaaatatcc ttggtcttct tgaagacgca
     9781 ggcattccat tccccttgaa tcatatgggt ttcaaggaaa aatccagctg actcagccga
     9841 ctggcgcacc atgtcccact tgtccttgat aatgccactc atgatgaggt agccttcatc
     9901 ctttaccaag cgataagcat cctccgtcag atgaatgaga atatccgcca agatattagc
     9961 cacgatgaca tctgcttcaa tctcaactcc cttaagcaag tctcctgctg ctacatggat
    10021 attttccata ccagtgttga gctcaatatt ttcctgagcg acacgaaccg ccacatcatc
    10081 caagtcatag gcgaaaatct ccttggcacc taggagtgag cttgcaatag aaagaacccc
    10141 tgaaccagtc cccacatcta gcaccgtttc gccaccacga agaacctgtt ccaaggcaaa
    10201 aaggctcatc ttggtagttg ggtgggttcc agtaccaaaa gccatgccag gatccagctt
    10261 gataattttt tctcccgcag tcgcctcata gtctgtccaa gagggaacga tggtcaaatc
    10321 atgagtgatg cgagcaggtt catagtattt cttccagttg tctgcccagt cttcctcagc
    10381 caaggcagtc gtacctattt ttaactctcc caaatccata aaatccgtca attctgctaa
    10441 gcgagcctgc aagtccgcct caaccactgt catatccacc gtgtcagggt agtaggctgt
    10501 cactacgatt tcttcttgct gctccacctc tgggaaaatc tcgccaaaac gatccacatt
    10561 tcccatatag tccatgctgt cttcaatcgc gactccttgc gctcccagct caatcaagag
    10621 attggaaacc aactcctctc cctcacgctt cactgtaact tttaactctt gccatgtttc
    10681 cattattaag ataccaagcc cgtaaaacac aaaaccaaaa taggaaattc tctgaagacg
    10741 cttgtgtcta agagaagttt atctttttgg cacagtgttt agggcgggtt cagtttagaa
    10801 atgtaactga accatccttt ctaatcactt acttttaaat aatcttttaa tctctcttgc
    10861 aactgaggca caacttgact ggaactaaga aattcctcaa cattcatcag ctgatagccc
    10921 tgtccttcat ctccgaagat gatattgtca aattgttctt gtcttagctg accaaccata
    10981 aagaccgatt tcttgccttt aaaaattacg ctaggataaa tcttgctcca aagcagacag
    11041 tcttcatcta aatgaattcc cagttcctca taaacttcac gccgagcgca ttcaaaaggg
    11101 ctttcgtccc cttcacggcc accacctggc aactcccaca tgttgggaca agggatatcg
    11161 tccttgtcat cacgcaaaat cgtcagtagc ttatccccac aaaagagggc aatcttgcaa
    11221 ccttggaaat cagaaatttc tagttccatc ttcagttcct tctaacattt ccttttccag
    11281 ctctgctaac aagttttcat aatagcgttt ctcgtccctc aacattcgac tactatccat
    11341 tttctgtcta gcaatcttga gagccttacg agttcgatct acatctttct tcacctttaa
    11401 ttgataccag gcttgtatca cttgaagatt ggacagtttg agagacagaa acgatttgac
    11461 ctgtcgaata ctagcatatt gctccgcttg ctcaaaatct ccttccaaca aggcgatatg
    11521 aagcagggat agttgggcaa ctgtctgcat catcggagta gttgtcctct caagtaatgc
    11581 ttgaaactgc tgtttagcta cttcttcctt cccttccaaa atggaaactt caccttgcat
    11641 acctaataca ccatccgcaa aactccctcg tgcatcctca ggaactgctt gaacaaagtc
    11701 tttcaaatca tattcttgag gagccagcaa agtttgagca gaatgtctca ataccaggta
    11761 ggcgtatttg gtattttcag ggtgttgtag taattcccaa atttttgctc catcggtgat
    11821 gtcgactggc aaaatgttat ttaggaagaa agataaatta agaaaaatcc aagtccctgc
    11881 aaaataccag cttcttgtca aaaatccaaa cactatcgcc aataatatca agccgagatg
    11941 aaccatcaag cctcctgaaa gcatcaggat gattctttga tcgctttcat cctcttttaa
    12001 accaatgtat tgagcaccaa catttttcag aatggctgtt ctactaagat gaaacctgcc
    12061 tgactttttg gtcaaaataa aatgtcctaa tccaaaagcc accagccgat agcctgtcaa
    12121 gtagccacaa aaagcatgac ccagctcatg aagaataaag attaaataca tgcttagaag
    12181 agcgaaggca taaccaaaag taaaggctaa aactgcggaa taccccaact ctgcaaatgc
    12241 gattgttcca caagcaaaag ctagcataat aaagacaaca gctagcacat aaaccaaata
    12301 agtcccaatt ttcttcataa cacctccaac caactcctag tatcttggat aaggataaaa
    12361 ttctccctct tccaagccaa cttttccttc ttcaaagact tcttggttcc attccatgac
    12421 aaattcctct gcttctgggt cttccaaaaa gtccatgagg acatctagcc caacctcagc
    12481 agtatcttta aggaaaagca caaaataagc taaaaattca cgggaaaatc cttttttagg
    12541 caggtaagga ataacagtca aatagtcttc ctcattgact gttgacttag caggattgta
    12601 gaaaaggacc gcttcctcaa aaagaatgtc atctgatgaa acctctccgt cttcatccac
    12661 catctccaca cctgcagcat tttgcgcttc caatagaaaa ctcacttcta ccgcatggtt
    12721 gcgtttgtcc cagctaatct caaagtcaaa gggaaagttc ttgtccaact cttcctctaa
    12781 aacatctaaa aatccgtatg ttgccatttt gtcctctttc tatgcgactc tttaatcgcc
    12841 ccgattgctc ggaaatatgc taaaatagat actaccatct taccacaaaa ttattttatg
    12901 tcctaattat accatattac ctcatttaaa cccttggtat cagtgatttt cttaaaagtc
    12961 tgatttcttc atttctcata aaaatcaata taaaaagccc tcgaaagggc taataaatct
    13021 ataaaatcaa taggcgagta actagcacaa gtggacgtgc ttttttattg actattacca
    13081 cgataccacg cttaatctta ggcttgaact ttcttatctg caatagcgtc tgtcaaagtc
    13141 tgagaaaagt taagtcccat ttctcgtccc aacttatctg cccattttgg tatggtcaaa
    13201 gtctttttaa tgggttcctg acttcctagg tattctgata catcaacaga taccatagaa
    13261 ataaaagatt tatcaaggtc ataggttgac acgaaatctt catcatcttt aaaaggatca
    13321 ttatcaatta aagacaagct attgatatct gatggctgag gtaactctcc atcactctct
    13381 atcaaatctg caacagttat ccctagccac tccgacccca tagccaaagc ctcagaaatc
    13441 ccctctcctt gtgtagctga gtattcaaaa tctgggaaat ggacaaaata agtcgcttct
    13501 gttccgtctg tgtcgtcata ataaaataaa gctggatacg taactaacat ttcactacct
    13561 ccatatcaaa aagcagggac tgaattttac aacccagctt gctttcctat ccctctttca
    13621 gtgtacttat tcagctcacc atgaaggatt gtgataggtc tttccccttg cttctcgatt
    13681 ttaatatggg agcctttacc gcctctagtc tttatccaac catgggccgt aaagagttta
    13741 accatctctt tttgtgtcat aggcatagcg cttttacctc ctgacaacac cattataaca
    13801 cgtgttacac gtattgtaaa ggagtgatac ttattattct attatacata aaagccccta
    13861 gatgtggttc taagggaaac caatttattc agacctattt ttctaatgag tagtaaaaac
    13921 tgcttcttta tcgagcaatt catcatctgt atagtcaatt gtaaaagtat ctcgatctaa
    13981 gacagattga ggcggagttg aatgaatcat aggaccactg cgtactctat attttttatc
    14041 tccaattttt acaaactgat actcttcgaa aatcaaattc aaaccacgtc aacgtcgcct
    14101 taccgtactc aagtacagcc tgcggctagt ttcctagttt gctctttgat tttcattgag
    14161 tatgattaac tctcaagtct tcgaaatcag gattttcaac agttattaca aggaggcgat
    14221 ttactacttc aaaaacatca attattctat ttttcatatt ttttcaaccc attattagaa
    14281 tgaacttctt ggtaagcaaa atcaagttta gatttaatgt tttcgtacaa atctaaaatc
    14341 tcttttggag tatcttcccg gaagaaaagt tttcttttcc ctgaaataac ttgatcacta
    14401 agaatccaat gacgaatttg ttttgtaaaa at
//
LOCUS       DAVAZT010000052        14254 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVAZT010000052 DAVAZT010000000
VERSION     DAVAZT010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14254
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.052"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            3..350
                     /locus_tag="VQT45_001660"
     CDS             3..350
                     /locus_tag="VQT45_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359952.1"
                     /translation="MLRLPYKKQKISHFTVSEDKDICRYIRQQLYYQNLFWMKEQAEA
                     YQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPP
                     AFYQQYFLKNMVE"
     gene            369..2171
                     /gene="pepF"
                     /locus_tag="VQT45_001661"
     CDS             369..2171
                     /gene="pepF"
                     /locus_tag="VQT45_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET2359953.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEVLKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTFYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGIYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            2173..2886
                     /locus_tag="VQT45_001662"
     CDS             2173..2886
                     /locus_tag="VQT45_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HET2359954.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELENFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            2953..3894
                     /gene="prsA"
                     /locus_tag="VQT45_001663"
     CDS             2953..3894
                     /gene="prsA"
                     /locus_tag="VQT45_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HET2359955.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(4011..4352)
                     /locus_tag="VQT45_001664"
                     /pseudo
     CDS             complement(4011..4352)
                     /locus_tag="VQT45_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            4765..4860
                     /locus_tag="VQT45_001665"
                     /pseudo
     CDS             4765..4860
                     /locus_tag="VQT45_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(5113..5733)
                     /locus_tag="VQT45_001666"
     CDS             complement(5113..5733)
                     /locus_tag="VQT45_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET2359956.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(5733..6215)
                     /locus_tag="VQT45_001667"
     CDS             complement(5733..6215)
                     /locus_tag="VQT45_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HET2359957.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(6215..7057)
                     /locus_tag="VQT45_001668"
     CDS             complement(6215..7057)
                     /locus_tag="VQT45_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HET2359958.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(7152..7952)
                     /locus_tag="VQT45_001669"
     CDS             complement(7152..7952)
                     /locus_tag="VQT45_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HET2359959.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            8096..9475
                     /gene="glmU"
                     /locus_tag="VQT45_001670"
     CDS             8096..9475
                     /gene="glmU"
                     /locus_tag="VQT45_001670"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HET2359960.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            9485..10030
                     /locus_tag="VQT45_001671"
     CDS             9485..10030
                     /locus_tag="VQT45_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2359961.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTARRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            10042..10356
                     /locus_tag="VQT45_001672"
     CDS             10042..10356
                     /locus_tag="VQT45_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HET2359962.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            10373..11065
                     /locus_tag="VQT45_001673"
     CDS             10373..11065
                     /locus_tag="VQT45_001673"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HET2359963.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNTQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            11142..11633
                     /gene="rocS"
                     /locus_tag="VQT45_001674"
     CDS             11142..11633
                     /gene="rocS"
                     /locus_tag="VQT45_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HET2359964.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            11731..12321
                     /locus_tag="VQT45_001675"
     CDS             11731..12321
                     /locus_tag="VQT45_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HET2359965.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGVLDLSQLFD"
     gene            12330..14093
                     /locus_tag="VQT45_001676"
     CDS             12330..14093
                     /locus_tag="VQT45_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HET2359966.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         4485 a         2552 c         2969 g         4248 t
ORIGIN      
        1 aaatattgcg tcttccctat aagaaacaaa aaatatctca ttttacagtt tctgaggaca
       61 aggacatctg tcgctatatc cggcaacaac tttattatca aaatctcttt tggatgaaag
      121 aacaagcaga agcctatcaa aagggagaaa atatcctgac ttatggactg aaagaatggt
      181 atccacaaat tcgaccaata gtgggcaaat ttttccagat tgaacaagac ttgactagct
      241 attatcagca cttttatacc tattaccaaa aaaatcctca aaatgattgg caaaagcttt
      301 atccaccagc cttttatcag caatatttct tgaaaaatat ggtagaatag aaaggatgga
      361 ggaatctaat ggtattacaa agaaatgaaa taaatgaaaa agatacatgg gatctatcaa
      421 cgatctaccc aactgaccag gcttgggaag aagtcttaaa agatttaaca gaacaattgg
      481 agacagtagc ccagtatgaa ggccatctct tggatagtgc ggataaccta ctagaaatca
      541 ctgaattttc tcttgaaatg gaacgccaga tggagaagct ttacgtttat gctcatatga
      601 agaatgacca ggatacacgt gaagctaagt atcaagagta ctatgccaag gccatgacat
      661 tctacagcca gttagaccaa gccttttcat tctatgagcc tgaatttatg gagattagcg
      721 aaaagcagta tgctgacttt ttagaagctc aaccaaagct gcaggtttat caacactatt
      781 ttgacaagct cttgcaaggc aaggatcacg ttctctcaca acgtgaagaa gaattattgg
      841 ctggagctgg agaaatcttt ggttcagcaa gtgaaacctt cgctatcttg gacaatgcgg
      901 atattgtgtt cccttatgtc ctagacgatg atggtaaaga agttcagcta tctcatggga
      961 tttacacacg tttgatggag tctaaaaaac gtgaggttcg ccgtggtgcc tatcaagctc
     1021 tttatgcgac ttacgaacaa ttccaacaca cctatgccaa aaccttgcaa accaatgtta
     1081 aggtgcaaaa ttaccgtgct aaagttcgta actacaagag tgctcgtcat gcagccctcg
     1141 cagcgaattt tgttccagaa agtgtttatg acaatttggt agcagcagtt cgcaagcatt
     1201 tgccactctt acatcgctat cttgagcttc gttcaaaaat cttggggatt tcagatctca
     1261 agatgtacga tgtctacaca ccgctttcat ctgttgaata cagttttacc taccaagaag
     1321 ccttgaaaaa agcagaagat gctttggcag tcttgggtga ggattacttg agccgtgtta
     1381 aacgtgcctt cagcgagcgt tggattgatg tttacgaaaa tcaaggcaag cgttcaggtg
     1441 cctactctgg tggttcttac gataccaatg cctttatgct tctcaactgg caggacaatc
     1501 tggacaatct ctttactctt gttcatgaaa caggtcacag tatgcattca agctatactc
     1561 gtgaaactca gccttatgtt tacggagatt actctatctt tttggctgag attgcctcaa
     1621 ctaccaatga aaatatcttg acggagaaat tattggaaga agtggaagac gacgcaacac
     1681 gctttgctat tctcaataac ttcctagatg gtttccgtgg aacagttttc cgccaaactc
     1741 aatttgctga gtttgaacac gccattcacc aagcagatca aaatggggag gtcttgacaa
     1801 gcgatttcct aaataaactc tacgcagact tgaaccaaga gtattatggt ttgagtaagg
     1861 aagacaatcc tgaaatccaa tacgagtggg ctcgcattcc acacttctac tataactact
     1921 atgtatatca atattcaact ggctttgcgg ccgcctcagc cttggctgaa aaaattgtcc
     1981 atggtagtca agaagaccgt gaccgctata tcgactacct caaggcaggt aagtcggact
     2041 atccacttaa tgtcatgaga aaagctggtg ttgatatgga gaaggaagac tacctcaacg
     2101 atgcctttgc agtctttgaa cgccgtttaa atgagtttga agcccttgtt gaaaaattag
     2161 gattggcata aaatggttga atcgtatagt aagaatgcta accataacat gcgtcgtcct
     2221 gtcgtcaaag aagaaattgt agacttgatg cgtcagcgtc aaaagcaggt cacaggtttc
     2281 ttgaaagaat tggaaaactt tgcccgcaag gaaaatattc ctattattcc ccatgaaacg
     2341 gttgcttatt tccgttttct tatggaaacc atgcagccta aaaatattct ggaaattggg
     2401 acggctatcg gtttttcagc tctcttgatg gctgaacatg cgccaaatgc taagattaca
     2461 actattgatc gtaatccaga aatgattggt tttgccaagg aaaattttgc ccagtttgac
     2521 agtcgcaagc aaatcactct cctagaggga gatgcggtgg atgtcttatc tacactgaca
     2581 gagtcttatg atttcgtctt tatggattct gccaagtcta aatacatcgt ctttctgcca
     2641 gaaatcctca aacatttgga agttggtggt gtggttgtct tggatgatat ttttcaaggt
     2701 ggtgatgttg ccaaggatat tatggaagtc cgtcgtggtc agcgaaccat ttatcgaggc
     2761 cttcaaaaat tatttgatgc aaccttagac aatccagaac tcaccgcaac attagtgcct
     2821 ttaggagatg gtattctcat gcttcgtaaa aatgtagcag atgttcaact gtctgaaagc
     2881 gaatgatttt cagaaaaatt taagaaaaaa tagtaaaata gatagagtaa cacttatctc
     2941 aaaggagtag acatgaagaa aaaattattg gcaggtgcca tcacactatt atcagtagca
     3001 actttagcag cttgttcgaa agggtcagaa ggggcagacc ttatcagcat gaaaggggat
     3061 gtcatcacag aacatcaatt ttatgagcaa gtgaaaaaca acccttcagc ccaacaagtc
     3121 ttgttaaata tgaccatcca aaaagttttt gaaaaacaat atggctcaga gcttgatgat
     3181 aaagaggttg atgatactat tgccgaagaa aaaaaacaat atggcgaaaa ctaccaacgt
     3241 gtcttgtcac aagcaggtat gactcttgaa acacgtaaag ctcaaattcg tacaagtaaa
     3301 ttagttgagt tggcagttaa gaaggtagca gaagctgaat tgacagatga agcctataag
     3361 aaagcctttg atgagtacac tccagatgta acggctcaaa tcatccgtct taataatgaa
     3421 gataaggcca aagaagttct cgaaaaagcc aaggcagaag gtgctgattt tgctcaatta
     3481 gccaaagata attcaactga tgaaaaaaca aaagaaaatg gtggagaaat tacctttgat
     3541 tctgcttcaa cagaagtacc tgagcaagtc aaaaaagccg ctttcgcttt agatgtggat
     3601 ggtgtttctg atgtgattac agcaactggc acacaagcct acagtagcca atattacatt
     3661 gtaaaactca ctaagaaaac agaaaaatca tctaatattg atgactacaa agaaaaatta
     3721 aaaactgtta tcttgactca aaaacaaaat gattcaacat ttgttcaaag cattatcgga
     3781 aaagaattgc aagcagccaa tatcaaggtt aaggaccaag ccttccaaaa tatctttacc
     3841 caatatatcg gtggtggaga ttcaagctca agcagtagta catcaaacga atagtccaaa
     3901 tcaatgagtc agggaaaaaa actcgacttc aggaaaaaat gaagcaaaca ttcccacaat
     3961 aaaacgcata gtacaaggtt tgtactgacc ccaaaagtta gacaattaat ttatctgaag
     4021 gatttagttc tgtattgcac agggctaagt ccttttagtt ttaccttaat tctcttattg
     4081 ttgtaataat caatatagtc tataatggct tgttccaatt gattaagtga tttaaatgtt
     4141 ttctcatagc cataaaacat ttcggatttt aaaatgccaa agaaagattc catcctaccg
     4201 ttgtcttggc tgtttccttt gcgtgacata gatgcttgaa ttcccttact ctctaggaag
     4261 cgatgataag aatcgtgttg gtattgccag ccttggtcac tatggagaat cgtattctcg
     4321 tagtgcttct ctttgaatgc ctgttccaac attaacgatc aatcaattta atcatgtacc
     4381 taatattaga attgtttatc ccaaatttat ttgaaagctt ctctaagcta tatccttgtt
     4441 ttctaagttc atagatctga actttatcat cataagttaa tttcataata aaaacacccc
     4501 aaaagttaga ttttttctgt ctaacttttg gggtgtagtt catgtacacc tgatatgatg
     4561 cgttttataa ttttaaagac tttttgacca gcctcatttt tttaacttga tactcagtga
     4621 aaagcaaaga ttaaactagg aagctagctg taggctgctc aaagaacagc tttgaggttg
     4681 cagataaaac ttgtgaggtc accaacatat ataatgtgaa gctgacgtga cttgaataga
     4741 ttttagaagg gtatgagtct ggaagtttta atggataatg caagattcca tagaatgggt
     4801 aagctagagt tcttatgtga agagtttggg cataaacttt taccttttcc tccctactca
     4861 tcttagtata gaaaagtgaa tctaaaatag tacataactg cttctaaaac attcttataa
     4921 attgatttaa attctcaaat catattattc agttcttatt tcattttgct ctacaatcct
     4981 gttgagaaga cacgtgttca tatcaaaaag gtattggcaa gttgcaatac ctttttacaa
     5041 ggttcttttg tcttattttt gtttcaactg actatatctc ctatggttct agttcagaag
     5101 gctaggctat aattatgatt gataagaagt atcattccaa gtattgagag tgaatgtttc
     5161 aaaatcatgg gtttctataa tggtcaggct ggcatttgct agaccgccat ctttacgaag
     5221 aagtggttct ttatagccta ggagagtacg aagactggca gtaagattgg cgccgtgtcc
     5281 gacaattaga atacgctcag ctggactatc ttttaatgat ttgataaatt ggatggtccg
     5341 ttgagttgta ctatagaggg attcggctcc gaacattcga gtgtcaaatt gagcaagatt
     5401 tgaacgaaaa gcctggattt gttgcgggta aatagcttcc aaggttgcaa ttttcaaacc
     5461 ttctaacttc ccaagttgcc attcacggag attaggaacg atttctaaag aacagggggt
     5521 atagagttga ctttggataa tctcagcaga tttgaccgct cgaggtaaat cacttgaata
     5581 aatctgatca aaaggaattt ccttgagata ctggccaagt cgttttaggg tttcaatgga
     5641 ttcaggaaga agaggagaat caccgctagc accttgaaaa cgaccttctt ggttccagag
     5701 ggtacgaccg tggcggacaa agtagagttt cattacttga tgtcctccaa aatatctaca
     5761 aagtctgcct ttacaaagct agccaagtct tgtggcgcga cgataatgct gtgtccgact
     5821 tcgcctgcag agacaatcat tcgatccaaa tctagagcaa ttttatcgat aaaaatggga
     5881 taattgtgtt tctgacgaat tccgacagga ttattggctc catgaatgta accagttgtt
     5941 ttttctaagt ccttttgtgg aatcatgctc acttttttat tgccagaaat tttagctagt
     6001 ttcttttcag acaagtgctg agtgataggg acaattccga taatcggtcc ggtcttgtct
     6061 cccaaaagcg ccaaggtttt gaaaatctga tctcgttcat aaccttgagg aagctctcct
     6121 tctagggcat tgatttgaat cccctgatga gggatagctg ctttagatag gatttgttcc
     6181 accaatgttt ttttgatttt aacttttttt gccattattt atatttatcc tccaattgac
     6241 tcatccaaat accaagccag attcccagcg caaagaagaa ggcgatgatg acataaccga
     6301 caagtgaaag tcctgtgtat tggatacttt cagcgtttcc tgcatttgga attaagatca
     6361 aaagggtact tgataggacg ataccgatga tgaaatgata gacgcgtgag tggtagttgt
     6421 ttaaggcata atccatcaat tttgaaaaaa cgatgagagt tgcacctgca ccaattccaa
     6481 tcggaaagaa ggttcccaag agatcaaaag ttttaaaacc agtcaacata ggagcataga
     6541 gtcccaaaat caaaagtaag ttcgatgggc tgaggccagg aaccaagacg ccaagggcca
     6601 atagtgcgcc tgctaggacg aagttaagaa agctggcgct taaggttcca acgacaaaat
     6661 ttaaggcata gagtcctaat ccagaaatga taaaggttgt ccataaccaa gctaaatcaa
     6721 tcttgtctcg gtcagattct cgagttgatt ctttgaggag gctaggaact gtaccgataa
     6781 tagctcccgc aaagctccat aatacaaaga cctgataatt ttcaagcagg tattcaatcg
     6841 ggtaggaaaa taagccgatt cccagaagca taccgatggc aactggaata aagtacaaaa
     6901 cattttcttt aaggtcttta aagggatggg ccagaaagcc aatcattcgt tcatagattc
     6961 ctaagattgc tgctagaacc cctccggaaa ttcccggtag gataaatcca agagcaatta
     7021 caatcccttt aataacgcgt gctaaccatg agagcatata tttcctccaa ctatttctat
     7081 ttcaaaaatt ccttactata ttgtatcaca atcagacaca aaaagaaaaa gcaaatgata
     7141 aacaaatgct tttaaggttt taaaaaaagt tttcgaaagg tttcttcttt attttttaag
     7201 ggagagataa cgttgatatc taaatcgtgg tcaaagccgg caatttttcc tttagatgtg
     7261 tattggtgaa tatcataatc taaatcagtt ttaggactgc tctccaaaaa tcctgagtct
     7321 gagccgtagg acggaatcca aacagaggta aacttgcctg tatcaatact gtgttcttcc
     7381 atgaagtaga caccaacgta gatgccgatg tttttagcac ctagtgatgc tagttttgct
     7441 cgaaagtttt cgacaccttc gttcatatta gacatggttt tgtcttccac gtcaagccaa
     7501 tagtaactag ggctgtaagg agaggcagca ttgtagaaaa cttcggcagc cttttccatt
     7561 tcttggacac tttttccagc tacataagcg tagacagcaa ctgggacatt ccgcttttga
     7621 agttcagtga tatgactctt ataggccttg tctattccat tgataaatga agcatcattt
     7681 tcttttgttg tttgagcacc actgtgaaca cgaacaatag cacctgaaat attttgtgag
     7741 agggcatcgt agttgatttc ctcaggacgc tgccagccag agaggtcaat aatcggtttg
     7801 tctaagtgtt tcaaagcctg tgcttcaatc tgtgctatat tggattttgt tttaaacgat
     7861 tggctgtcat taagtgggcg attgatgatt aaaatgaaca tcataatccc aaaaaaacta
     7921 aataaaataa gtggatgaat ttgttttctc atatcttata agtctaccct aaaaatcaaa
     7981 aaaaatcaaa aaaatgggtt aaggaagaga ctttagagca ttttttcatt caagagtgcg
     8041 gaatgatttg aaatatggta taataaaagg gaatttctac agaaaagaga agattatgtc
     8101 aaattttgcc attattttag cagcgggtaa agggactcgc atgaaatctg atttgccaaa
     8161 agttttgcac aaggttgcgg gtatttctat gttggaacat gttttccgta gtgtgggagc
     8221 tatccaacct gaaaagacag taacagttgt aggacacaag gcagaattgg ttgaggaggt
     8281 cttggctgga cagacagaat ttgtgactca atctgaacag ttgggaactg gtcatgcagt
     8341 tatgatgaca gaacctatct tagaaggttt gtcaggacac accttggtca ttgcaggaga
     8401 tactccttta atcactggtg aaagcttgaa aaacttgatt gatttccata tcaatcataa
     8461 aaatgtggcc actatcttga ctgctgaaac ggataatcct tttggctatg gacgaattgt
     8521 tcgtaatgac aatgctgagg ttcttcgtat tgttgagcag aaggatgcta cagattttga
     8581 aaagcaaatc aaggaaatca acactggaac atacgtcttt gacaacgagc gtttgtttga
     8641 ggctttgaaa aatatcaata ccaataacgc tcaaggcgaa tactatatta cagacgtcat
     8701 tggtattttc cgtgaaactg gtgaaaaagt tggcgcttat actttgaaag attttgatga
     8761 aagtcttggg gtaaatgacc gtgtggcgct tgcgacagct gagtcagtta tgcgtcgtcg
     8821 catcaatcat aaacacatgg tcaacggtgt tagctttgtc aatccagaag caacttatat
     8881 cgatattgat gttgagattg ctccggaagt tcaaatcgaa gccaatgtta ccttgaaagg
     8941 gcaaacgaaa attggtgctg agactgtttt gacaaacggt acttatgtag tggacagcac
     9001 tatcggagca ggagcggtca ttaccaattc tatgattgag gaaagtagtg ttgcagacgg
     9061 tgtgacagtc ggtccttatg ctcacattcg tccaaattca agtctgggtg cccaagttca
     9121 tattggtaac tttgttgagg tgaaaggatc ttcaatcggt gagaatacca aggctggtca
     9181 tttgacttat atcggaaact gtgaagtggg aagcaacgtt aatttcggtg ctggaactat
     9241 tacagtcaac tatgacggca aaaacaaata caagacagtc attggagaca atgtctttgt
     9301 tggttcaaat tcaaccatta ttgcaccagt agaacttggt gacaattccc tcgttggtgc
     9361 tggttcaact attactaaag acgtgccagc agatgctatt gctattggtc gcggtcgtca
     9421 gatcaataaa gacgaatatg caacacgtct tcctcatcat cctaagaacc agtaggagcc
     9481 tatcatggag tttgaagaaa aaacgcttag ccgaaaagaa atctatcaag gaccaatatt
     9541 taaactggtc caagatcagg ttgaattacc agaaggcaag ggaactgccc gacgggattt
     9601 gattttccac aatggggctg tctgtgtttt agcagtaacg gatgaacaaa aacttatctt
     9661 ggtcaagcag taccgcaaag ctatcgaggc tgtctcttac gaaattccag ccggaaaatt
     9721 ggaagtagga gaaaacacag cccctgtggc agctgccctt cgtgaattag aggaagaaac
     9781 agcctataca gggaaattag aactcttgta cgatttttat tcagctattg gcttttgtaa
     9841 tgagaagtta aaactatatt tagcaagcga tttgacaaaa gtggaaaatc cgcgtccgca
     9901 ggatgaggat gaaaccttgg aagtccttga agtgagctta gaagaagcga aagaattaat
     9961 ccaatcaggt catatctgtg atgccaagac aattatggct gttcagtatt gggagttgca
    10021 gaaaaaatag aggaggtcag tatgggtaaa tctttattaa cggatgaaat gattgaaaga
    10081 gctaatagag gcgaaaaaat ttcaggtcct cctttgctag atgataatga ggaaactaag
    10141 attttaccaa cctcttcttc ccgttttggt tatgccaatc ctaaggatca tggttttagc
    10201 caggaaacct tgaagattca ggtcgaacca tctattcata aaagccgtcg tattgaaaat
    10261 accaagagaa atgtcttcaa ttctaagttg aataaaatct tatttgcggt catctttctc
    10321 ttgattttgc ttgttttagc aatgaaactt ttgtaataga aaaggaattg aaatgaaaat
    10381 aggaattatt gctgctatgc cagaagaact ggcttatctg gtccagcatt tagataatac
    10441 ccaggagcaa gttgttttgg ggaataccta tcatacagga accattgctt ctcatgaagt
    10501 cgttcttgta gaaagtggaa ttggtaaggt catgtctgct atgagtgtgg cgattttggc
    10561 tgatcatttc caggtggatg cccttattaa tacgggttca gctggggcag tagcagaagg
    10621 tatcgctgtt ggggatgtcg tgattgctga caaattagcc tatcatgacg tggatgtcac
    10681 agcttttggc tatgcttatg gacaaatggc gcaacaaccg ctttatttcg aatcagacaa
    10741 aacctttgtt gctcaaatcc aagagagttt atctcaattg gaccaaaact ggcatcttgg
    10801 tttgattgct acaggagata gttttgttgc aggaaatgac aagatagaag cgattaagtc
    10861 ccatttccca gaagttttag ccgtggagat ggagggggca gctattgctc aagcagcgca
    10921 tgccctcaat ctcccagtct tagtcatcag agctatgagt gacaatgcca accatgaagc
    10981 aaacatcttt tttgatgagt ttattatcga agctggacgt cgctctgccc aagtcttgtt
    11041 gacctttttg aaggctttag attaagcgga aatttgacag tttttctagc ttatgataag
    11101 atttaagtaa agaaaagcta gaaaacgttt cagaggatat tatgagtatt gaaatgaccg
    11161 tcagtgagat tgcagaggtc ttaggattat ctcgccaagc aatcaataac cgtgtcaaag
    11221 aattaccaga agaagacaca gataaaaatg acaaaggggt aacagttgtt accagaagtg
    11281 gcttgattaa gctagaagaa atctataaaa aaacgatttt tgaagatgag cctgtcagtg
    11341 aagatgtcaa acaacgtgaa ctgatggaga ttctagtgga tgagaagaat gcagaaattc
    11401 ttcgtcttta tgaacaatta aaagccaagg atcgtcagtt atcagaaaaa gacgagcaga
    11461 tgcgtatcaa agaccgtcag attgctgaga aagacaaaca attagatcag caacaacaat
    11521 tgacccttca agccatgaag gatcaagaaa atcttaagct agagctggac caagcaaaag
    11581 aagaagtcca atccactaag aaaggctttt ttgctcgttt atttggagga taatcaagga
    11641 gctgtttagg ttaaatgcta acctgatggc ttcttttgtt tgtgaatagt atagttgatt
    11701 agaacagaga cagtagagga gaggtacaga atggaacgat tagaagatta cattgctttt
    11761 gacttagaat ttaatcagca cgaaggacaa acacacttga ttcaagtatc ggcagtgcgt
    11821 tttagagatg gtcgggaaat cgatgcctat gattcctatg ttcataccag cgtccctcta
    11881 aaaagcttta tcaatggttt gaccgggatt acagctgaga ccttaaaaga tgctcctcca
    11941 gttgagaaag tcttagaaga attccaagag tttgtgggtt ctttgctgat gataggctac
    12001 aatgctgcta aaagtgattt acctatttta gcagagcatg gtttagacta tagccaacag
    12061 tacaaggtgg atttgtatga tgaagctttt gaacgtcgga gttcagattt acatggtatt
    12121 gccaatctca aattgcaaac tgttgcctca tttcttggat ttcaaggtca gtctcataat
    12181 agtttagagg atgctcggat gacggcgcgt gtttacgaat ccttcttaga gtcggatcaa
    12241 gctagggaat tgttagagac agaaagtagc ttatcaaaca atccttttgg tgtcttggac
    12301 ttgtctcaat tatttgacta ggagtgccta tgaaacctga aaaacctaaa aaattgggtc
    12361 ttaaacagat ttacctcaat cttgataaaa tcctctttct atttttcttg atttttatga
    12421 tagtggagta tttgtgggta ccattcaatt catggttggc tagcttctta ttagatcaga
    12481 caggttatct ttttatttcc tataacaatg tcttagccat ccttactcat tctccattga
    12541 ttagtctagc ttttttagcc ttgattgtaa ttaaccttct ggttgcttat tttcaaatag
    12601 gactcctctt tattggtgct cgtcatctcc tctataatga aaagcgaagg ctaattgagt
    12661 atatccgcaa ggttttccat gaaagttttg gatttatgaa aaagctaact tgcgctaaag
    12721 ccttgtttat ctttttctat atagctatgc tttttccttt tatacggaaa atgctgaaga
    12781 tttattatct taataaaatc gtcattccag agtttatcca agcttattta gaagataaat
    12841 attggatgtg gtggctgagc atcctacttc tatctcttat ctttctctat gtctctgtca
    12901 gattgatgtt tgcccttccg aagattgtat atgatcagct gactgttcga gaagcagtga
    12961 tgtttagctt ggagaaaacc aagaagagag ttacttttta tgcttggaat ttattttaca
    13021 tcttgctcaa agcacattta ttattttatc ttcctttgat tcctttatta ttggctcaaa
    13081 ctttggtaga tgatatcact cagagagagt ctctgattct tggtattttg aattttgtcg
    13141 tgattaaaaa tctctattat atggctctga cttatttttt ggttaaattt gtttcatttt
    13201 tgacaggaaa ggagctggat atgcttccta ggagagaaaa agatcacatc gtgcgatggg
    13261 gtgtcatgac ttgtgccagt cttttctttg ccttagaagg ttatatttat ctggaggctc
    13321 ccatggttca tctacctcaa cttatttctc accgaggggt ttccaatgca aatgggattc
    13381 aaaatacagt agagtccttg gaaactacag cacaactcaa accagacttg gtggagacgg
    13441 acgtgcagga aacaaaagat gggcagtttg tcatgatgca tgatgctaac ttgaaaaatc
    13501 tagcaggtat caataaaagt cctcaagact taaacttgga ggagcttaaa gggattgata
    13561 tttttgaaaa tggctaccag actaaaattt caagctttga agattatctc agtcgagcca
    13621 acgaacttgg tcaaaaatta ctaattgaaa ttaaaaccag taaaaaagat agtccagaca
    13681 tgatgaaccg ctttttagcc cgttatgctg caaagctcaa gatttatgga catcaaatcc
    13741 agtctttaga ctaccatgtt gtcgaaaaag taagacagta tgatgccgaa ctgccagttt
    13801 atttcatcat gccctacaat tctgtctttc ctaaaacaag agcgacagga tatactatgg
    13861 agtactcaac cttggatgaa tattttgtaa gcaaactatg gacaacggat cagaaacttt
    13921 atgtctggac tgtcaatgat tcagaagcta tcagcaaatc tcttcactta ggagtagatg
    13981 gagtgattac agatgatttg gaaaaagttc agcgggaaat agaagtagcc caagaagatc
    14041 cagaatatac ggatttgctc ttgaaaaaag cattggaatt ctttgaattt tagtaataaa
    14101 aaagaggaac ggttgttcct cccatgatag gtaagtattc ttgtgaatgc ttgctttttt
    14161 gtggttgcaa tccgtttacg agaattgttt gtattgttct tgtttcaatt tactttatag
    14221 tgctttgaag ttggaatgct acactataac ttct
//
LOCUS       DAVAZT010000053        14075 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVAZT010000053 DAVAZT010000000
VERSION     DAVAZT010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14075
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.053"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(394..2085)
                     /locus_tag="VQT45_001677"
     CDS             complement(394..2085)
                     /locus_tag="VQT45_001677"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HET2359967.1"
                     /translation="MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            2221..2667
                     /gene="argR"
                     /locus_tag="VQT45_001678"
     CDS             2221..2667
                     /gene="argR"
                     /locus_tag="VQT45_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET2359968.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            2718..5252
                     /gene="mutS"
                     /locus_tag="VQT45_001679"
     CDS             2718..5252
                     /gene="mutS"
                     /locus_tag="VQT45_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HET2359969.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKLDSQNNFLVAIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSCQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPALAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLITGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTENPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            5399..7093
                     /gene="patA"
                     /locus_tag="VQT45_001680"
     CDS             5399..7093
                     /gene="patA"
                     /locus_tag="VQT45_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HET2359970.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDVPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQEGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(7423..7692)
                     /locus_tag="VQT45_001681"
                     /pseudo
     CDS             complement(7423..7692)
                     /locus_tag="VQT45_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            7884..9650
                     /gene="patB"
                     /locus_tag="VQT45_001682"
     CDS             7884..9650
                     /gene="patB"
                     /locus_tag="VQT45_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HET2359971.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTHVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            9789..10478
                     /locus_tag="VQT45_001683"
     CDS             9789..10478
                     /locus_tag="VQT45_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET2359972.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLDEL"
     gene            10482..10661
                     /locus_tag="VQT45_001684"
     CDS             10482..10661
                     /locus_tag="VQT45_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359973.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            10648..11997
                     /locus_tag="VQT45_001685"
     CDS             10648..11997
                     /locus_tag="VQT45_001685"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HET2359974.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            12121..13581
                     /locus_tag="VQT45_001686"
     CDS             12121..13581
                     /locus_tag="VQT45_001686"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HET2359975.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            13595..14029
                     /locus_tag="VQT45_001687"
     CDS             13595..14029
                     /locus_tag="VQT45_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET2359976.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNTYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT         4111 a         2714 c         3180 g         4070 t
ORIGIN      
        1 cttcggatta cgaatgaatt tgattgctgg cattatcaat catgaactag gattctagtt
       61 ttgcaggaag tctattattt ggttaggtga attagtgaag cgtttaggca agtgtctctg
      121 gttacgacgt catggactct aaatcgatta tatttagggg tcatgactag tgaagcagtt
      181 agctagttcg catataagcg gctagcgtct aacaattagg aactttagtt ccaataactt
      241 taagattacg acgttttagg acataaatcg atcatattta tgtcctaaaa ctagtgaagt
      301 atgtcctaaa actagtgaag cgcctagcca aagtccgaat aggatttggc gttagttact
      361 tagattgctt tgcaatcaag taactttggc gatttacatc ttctctggcg cttctactcc
      421 aagcaagcga agggcttctt tgagaacgac tgcggttgcg tagctgaggg ctagacggct
      481 gtcgcgttct gggctttcat ccaagatacg tgtatgtgca tagtatttgt taaaggattg
      541 agccaggcta attgcaaatt tagcaatgat agaaggttca aagttatctg ccgcacggtt
      601 gataatacgt gggaagtctt gaatgagttt aatgatttcc cagctttcag tatcattcaa
      661 gctatagttg ccagctgttt ctggtttgaa atcggctttg cgtaagatag attggatacg
      721 agcgtaggca tattgaacgt aaggtccagt ttcaccctcg aaggatacca tagcctctag
      781 gtcgaagtcg tatccatttg tacggtcggt tttgaggtca tagaatttaa tggctccaac
      841 cccaacagca tgtgctactt ggtctttgtt ttctagttca ggatttttag cctcgatttg
      901 gaccttggca cggctaacag cctctgcaac agtaggctct agcaagatga cattcccttt
      961 acgagtagag agtttcttcc cttcttttgt aaccaaacca aaaggaacgt gagtaatgtc
     1021 gtcactccag tcgtagccca tctcttgcaa gacagctttg agctgtttaa agtgggcaga
     1081 ttgttcttga ccaacgacat agatagattt agcaaattgg tattcgtttt tacggtagag
     1141 ggctgcagcc aagtcacgtg tgatatagag agttgcacca tcagacttct tgatgagggc
     1201 tggatgttca attccgtatt tctcaagatt cacaacttgg gcaccttctg attcaagaag
     1261 tagtcctttt tcagaaagaa tgtctacaac tgcatccatc ttatcattgt agaaggcttc
     1321 tccgttatag ctgtcaaatt caaccttcaa ttcattgtaa aggcggttaa attccactaa
     1381 actttcatcg cggaaccatt gccaaagagc gagagcttcc tcatctccat tttcaagttt
     1441 acggaaccat tcgcgcgctt cttcatccaa gctagggtca ttttcagctt cagcgttgat
     1501 gcggacatag agtttaagga gttcatcgat tggatgagct tttacagctt cttcgtcgcc
     1561 ccattttttg taggcaacaa tcaacatccc aaattgttta ccccagtctc ccaaatggtt
     1621 gaccttgacc gtttgataac cgattttttg gaaaatatgt gacaagctat ctccgataac
     1681 agttgaacgc aggtggccaa tagaaaatgg tttagcgata ttcggactag acatgtcgat
     1741 aacaacattt tcttgtttac caatattttg gtcagcatag tgttcttttt cagtggtaac
     1801 agcttgcaat acttgagcag aaatggcaga tttatcaagg aaaaagttaa cgtaaggtcc
     1861 tgttgcgaca actttttcaa aggcttggct gttcattttt tcagccagtt cagccgcaat
     1921 catttgtggt gctttacgtt cgactttggc aagagaaaaa gcagggaaag cgatgtcacc
     1981 catttctgag tttttagggg tttccagtaa ctttaaaata gcctcttggt ccaggctatc
     2041 aatgatgcta gccaattcgc tagcaatcaa ttcttttgta ttcattaaga gctccttttt
     2101 ggacttttct actattttat cacaatttta aagaaagaag aaaaaatttt tgaaatctcc
     2161 tgtttttttg gtataatatg gttataaata tagttataaa tatgcacgca agaggatttt
     2221 atgagaaaaa gagatcgtca tcagttaata aaaaaaatga ttactgagga gaaattaagt
     2281 acacaaaaag aaattcaaga tcggttggag gcgcacaatg tttgtgtgac gcagacaacc
     2341 ttgtctcgtg atttgcgcga aatcggcttg accaaggtca agaaaaatga tatggtgtat
     2401 tatgtactag taaatgagac agaaaagatt gatttggtgg aatttttgtc tcatcattta
     2461 gaaggtgttg caagagcaga gtttaccttg gtgcttcata ccaaattggg agaagcctct
     2521 gttttggcaa atattgtaga tgtaaataag gatgaatgga ttttaggaac agttgctggt
     2581 gccaatacct tattggttat ttgtcgagat cagcacgttg ccaaactcat ggaagatcgt
     2641 ttgctagatt tgatgaaaga taagtaaggt cttgggagtt gctctcaaga cttatttttg
     2701 aaaaggagag acagaaaatg gcgatagaaa agctatcacc cggcatgcaa cagtatgtgg
     2761 atattaaaaa gcaatatcca gatgcttttt tgctctttcg gatgggtgat ttttatgaat
     2821 tattttatga ggatgcggtc aatgctgcgc agattctgga aatttcctta acgagtcgca
     2881 acaagaatgc cgacaatccg atccctatgg cgggtgttcc ctatcattct gcccaacagt
     2941 atatcgatgt cttgattgag cagggttata aggtggctat cgcagagcag atggaagatc
     3001 ctaaacaagc agttggggtt gttaaacgag aggttgttca ggtcattacg ccagggacag
     3061 tggtcgatag cagtaagctg gacagtcaga ataatttttt ggttgccata gaccgcgaag
     3121 gcaatcaatt tggcctagct tatatggatt tggtgacggg tgacttttat gtgacaggtc
     3181 ttttggattt cacgctggtt tgtggggaaa tccgtaacct caaggctcga gaagtggtgt
     3241 tgggttatga cttgtctgag gaagaagaac aaatcctcag ctgccagatg aatctggtac
     3301 tctcttatga aaaagaaagc tttgaagacc ttcatttatt ggatttgcga ttggcaacgg
     3361 tggagcaaac ggcatctagt aagctgctcc agtatgttca tcggactcag atgagggaat
     3421 tgaaccacct caaacctgtt atccgctacg aaattaagga tttcttgcag atggattatg
     3481 cgaccaaggc tagtctggat ttggttgaga atgctcgctc aggtaagaaa caaggcagtc
     3541 ttttctggct tttggatgaa accaaaacgg ctatggggat gcgtctcttg cgttcttgga
     3601 ttcatcgccc cttgattgat aaggaacgaa tcgtccaacg tcaagaagta gtgcaggtct
     3661 ttctcgacca tttctttgag cgtagtgact tgacagacag tctcaagggt gtttatgaca
     3721 ttgagcgctt ggctagtcgt gtttcttttg gcaaaaccaa tccaaaggat ctcttgcagt
     3781 tggcgactac cttgtctagt gtgccacgga ttcgtgcgat tttagaaggg atggagcaac
     3841 ctgctctagc ctatctcatc gcacaactgg atgcaatccc tgagttggag agtttgatta
     3901 gcgcagcgat tgctcctgaa gctcctcatg tgattacaga tgggggaatt atccggactg
     3961 gatttgatga gactttagac aagtatcgtt gcgttctcag agaagggact agctggattg
     4021 ctgagattga ggctaaggag cgagaaaact ctggtatcag cacgctcaag attgactaca
     4081 ataaaaagga tggctactat tttcatgtga ccaattcgca actgggaaat gtgccagccc
     4141 actttttccg caaggcgacg ctgaaaaact cagaacgctt tggaaccgaa gaattagccc
     4201 gtatcgaggg agatatgctt gaggcgcgtg agaagtcagc caacctcgaa tacgaaatat
     4261 ttatgcgcat tcgtgaagag gtcggcaagt acatccagcg tttacaagct ttagcccaag
     4321 gaattgcgac ggttgatgtc ttacagagtc tggcggttgt ggctgaaacc cagcatttga
     4381 ttcgacctga gtttggtgac gattcacaaa ttgatatccg gaaagggcgc catgctgtcg
     4441 ttgaaaaggt tatgggggct cagacctata ttccaaatac gattcagatg gcagaagata
     4501 ccagtattca actgattaca gggccaaaca tgagtgggaa gtctacctat atgcgtcagt
     4561 tagccatgac ggcggttatg gcccagctgg gttcctatgt tcctgctgaa agcgcccatt
     4621 taccgatttt tgatgcgatt tttacccgta tcggagcagc agatgacttg gtttcgggtc
     4681 agtcaacctt tatggtggag atgatggagg ccaataatgc catttcgcat gcgaccaaga
     4741 actctctcat tctctttgat gaattgggac gtggaactgc aacttatgac gggatggctc
     4801 ttgctcagtc catcatcgaa tatatccatg agcacatcgg agctaagacc ctctttgcga
     4861 cccactacca tgagttgact agtctggagt ctagtttaca acacttggtc aatgtccacg
     4921 tggcaacttt ggagcaggat gggcaggtca ccttccttca caagattgaa ccgggaccag
     4981 ctgataaatc ctacggtatc catgttgcca agattgctgg cttgccagca gaccttttag
     5041 caagggcgga taagattttg actcagctag agaatcaagg aacagagaat cctcctccca
     5101 tgagacaaac tagtgctgtc actgaacaga tttcactctt tgatagggca gaagagcatc
     5161 ctatcctagc agaattagct aaactggatg tgtataatat gacacctatg caggttatga
     5221 atgtcttagt agagttaaaa cagaaactat aaaaccaaga ctcactagtt aatctagctg
     5281 tagcaaggag acttctttga caattctcca cttttttgct agaatgacat cacacaaaca
     5341 gaatgaaaag gagctgacgc attgtcgctc ccttttgtct attttttaag gagaaagtat
     5401 gctgattcag aaaataaaaa cctacaagtg gcaggccctg gcttcgctcc tgatgacagg
     5461 cttgatggtt gctagttcac ttctgcaacc gcgttatctg caggaagtct taggcgccct
     5521 ccttactggg aaatatgaag ctatttatag tatcggggct tggttgattg gtgtggccgt
     5581 agtcggtcta gttgctggtg gactcaatgt tgtcctcgca gcctatattg cccaaggagt
     5641 ttcatccgac cttcgggagg atgccttccg taaaattcaa accttttctt atgctgatat
     5701 tgaacaattt aatgcgggaa atctagtcgt tcgaatgaca aatgatatca accagattca
     5761 gaacgttgtc atgatgacct tccagattct tttcagactt cccctcttgt tcatcggttc
     5821 gtttatccta gcggttcaaa ccttaccttc tctgtggtgg gtgattgttc tcatggtagt
     5881 cttgattttt ggtttgactg ctgtcatgat gggaatgatg gggcctcgtt ttgccaagtt
     5941 tcaaaccctt cttgagcgca tcaatgccat tgccaaggaa aatttacgtg gcgttcgtgt
     6001 ggtcaagtcc tttgtccaag aaaaagagca atttgctaag tttacagagg tctcagacga
     6061 gcttcttggt caaaaccttt acattggtta tgccttttca gtagtggaac cctttatgat
     6121 gttggttggt tacggggcgg tcttcctctc tatttggctg gtcgcgggaa tggttcagtc
     6181 ggatccgtct gttgttggtt ccatcgcttc ttttgttaat tacctaagcc agattatctt
     6241 taccattgtt atggttggat ttttgggaaa ttctgtcagc cgtgccatga tttccatgcg
     6301 tcgtattcga gaaattcttg acgcagagcc agctatgacc ttcaaggatg tcccagatga
     6361 agagttggtt ggaagcctta gctttgaaaa tgtgaccttt acctatccaa tggacaagga
     6421 accgatgctg aaagatgtga gctttactat tgaacctggt caaatggttg gtgtagttgg
     6481 agcgactggt gcaggaaagt caaccttggc tcaattgatt ccacgtctct ttgatccaca
     6541 ggaaggggct atcaaaatcg gaggtaagga tattcgagaa gtgagtgaag gaaccctgcg
     6601 taaaacagtt tccatcgttc tccaacgtgc cattcttttt agtggaacga ttgcagataa
     6661 cttgagacag gggaagggaa atgctactct atttgaaatg gagcgcgcag ccaatattgc
     6721 ccaggctagt gaattcattc atcgtatgga gaaaaccttt gaaagtccag ttgaagaacg
     6781 gggaaccaat ttctctggtg gacaaaaaca aaggatgtcg attgcgcgtg ggattgtcag
     6841 caatccacgt attctgattt ttgatgattc gacctcagcc ttggatgcca aatcagagcg
     6901 cttggtgcaa gaagctttga ataaggactt gaaggggacg acaaccatta ttattgctca
     6961 aaaaattagc tcggttgtcc atgcagacaa gatcttggtt ctaaatcaag gacgattgat
     7021 tggtcaaggc acgcatgcag acttggttgc caacaatgcc gtttaccgtg aaatctatga
     7081 aacacagaaa tgaaagacaa actataagaa aagtcaatag ttttatctaa actatttctt
     7141 atttcaattt gatgatttgg cgatgatttt agagcacggc aaaaagccct tgaaaaagtc
     7201 cattttttca aaggtaatcc tgtgttgatt tcagaaatta catcactttt tgttcgtcaa
     7261 atggcagctc ttttttagga tataaaacag ggttcggata agtttttttg caaggtggat
     7321 gatggctaca ttgtaatgtt ttccttgtta taacttagtc ttaagatagg ccttaaaagc
     7381 aggtgaaaag tgagggcatg ctttggcagc ttgtatgagt acctaccgca gatgagggga
     7441 accccgtttg accattcttc cagctaaatc aatctgacct gactgataaa tagaagaatc
     7501 cagtccagcg aaagcttgta attgagcagg attatcaaag gcatgaatat ttcgaatctc
     7561 ggctaaaatg accgccccta aacgattccc aatcccagta accgtcgtga tgaccgagtt
     7621 gaactcagcc atcaagtcat tgacacattt ttccgccttg tcaatgagcc tcttgtaatg
     7681 tttgatgatt tcattacacg agataaaacg tctatgcgtt atcaaactca ttaccaatta
     7741 aaacaaaaag ctgtggttag atcctttcgg aaatcgtcaa gcgattggag gaaatgaact
     7801 aatccacagc ggcttattcc aagtatacca cttgggcttt ggcagtagct aactgcgcta
     7861 aatataatat aaggaggagt aaaatgaaga cagttcaatt tttttggcat tattttaagg
     7921 tctacaagtt ctcatttgta gttgtcatcc tgatgattgt tctggcgact tttgcccaag
     7981 ccctctttcc agtcttttct ggacaagcgg tgacgcagct agccaattta gttcaagctt
     8041 atcaaaatgg caatccagaa cttgtatggc aaagcctatc aggaatcatg gtcaatcttg
     8101 gcctgctggt tttggttcta tttatctcta gtgtaatata catgtgtctc atgacgcacg
     8161 tgattgcaga atcgaccaac gagatgcgca aaggcctctt tggtaagctt gctcagttga
     8221 cggtttcttt ctttgaccgt cgacaagatg gcgatatctt gtctcatttt accagtgatt
     8281 tggataatat cctccaagcc tttaacgaaa gcttgattca ggtcatgagc aatattgttt
     8341 tatacattgg tctgattctt gtcatgtttt cgagaaatgt gacgctggct ctcatcacca
     8401 ttgccagcac cccattggct ttccttatgc tgattttcat cgtgaaaatg gcacgcaaat
     8461 acaccaacct ccagcagaaa gaggtaggga agctcaacgc ctatatggat gagagcatct
     8521 caggccaaaa agccgtgatt gtgcaaggaa ttcaagagga tatgatggca ggatttcttg
     8581 aacaaaatga gcgcgtgcgc aaggcaacct ttaaaggaag aatgttctca ggaattcttt
     8641 tccctgtcat gaatgggatg agcctgatta atacagccat cgtcatcttt gctggttcgg
     8701 ctgtactttt gaatgataag tctattgaaa caagtacagc cctaggtttg attgttatgt
     8761 ttgcacaatt ttcacagcag tactaccagc ctattatcca agttgcagcg agttggggaa
     8821 gccttcagtt ggcctttact ggagctgaac gaattcagga aatgtttgat gcagaggagg
     8881 aaatccgacc tgaaaaggct ccaaccttca ctaagttgca agaaagtgtt gaaatcagtc
     8941 atatcgattt ttcatacttg cctgataaac ctattttgaa agatgtcagc atttctgccc
     9001 ctaaaggcca gatgacagca gttgttgggc cgacaggttc aggaaaaacg actattatga
     9061 acctcatcaa tcgcttttat gatgttgatg ctggtggtat ttattttgat ggtaaagaca
     9121 ttcgtggcta tgacttagat agtcttagaa gcaaggtggg aattgtattg caagattcgg
     9181 tcttgtttag cggaacgatt cgagacaata tccgatttgg tgtgccagat gctagtcagg
     9241 aaatggttga ggtagcagca aaagcaaccc acattcacga ctatatcgaa agtttgcctg
     9301 ataagtacga tactcttatt gatgatgacc agagcatctt ttcaacaggg cagaagcaat
     9361 tgatttcaat cgctcgaacc ctgatgacag atccagaagt tctcattctc gatgaagcaa
     9421 cttcaaacgt agatacggtg acagaaagca agattcagca tgccatggag gtggttgtag
     9481 caggtagaac tagtttcgtc attgcccacc gcttgaaaac cattctcaat gcagatcaga
     9541 ttattgtcct taaagatgga gaagtcattg aacgtggtaa ccaccatgaa cttttgaagc
     9601 taggtggctt ttattcagaa ctctatcaca atcaatttgt tttcgaataa gaaagaagtt
     9661 gtcctatgtg ggcagctttt tcttgtccat aaaaaatgtt tatcacagcc ttaaaaaaaa
     9721 catattagac gaaagtcatt ttgagtgata tgataggact atcgttagca ttcgaaagga
     9781 gaggcatcat ggctagaacg gttgtaggag ttgctgcaaa tctatgtccc gtagacgcag
     9841 aaggcaaaat cattcattca tctgtatctt gtagattcgc agagatcatt cgtcaagtcg
     9901 gtggtctccc tttagtcatt cctgttggtg atgagtcagt tgtacgtgat tatgtggaaa
     9961 tgattgacaa actcattttg acaggaggcc aaaatgttca tcctcagttt tatggagaga
    10021 aaaagaccgt cgagagcgat gattacaatc tggtccgtga cgaatttgaa ttggcactct
    10081 tgaaggaagc gcttcgtcag aataaaccaa ttatggcaat ctgtcgcggt gtccaacttg
    10141 tcaatgttgc ctttggtgga accctcaatc aagaaatcga aggtcactgg caaggactac
    10201 ctttcgggac atctcactct attgagacag tagaaggaag cgtggtggct aagctatttg
    10261 ggaaagaaag tcaggtcaac tcagtccatc gtcaaagcat taaagatttg gcacctaatt
    10321 tccgtgtaac tgctattgat tcaagagacc aaactattga agcgattgag tctatcgacg
    10381 agcaccgcat tatcggttta cagtggcatc cagagtttct ggttaatgaa gaagatggca
    10441 atttagaatt atttgagtat ttattggatg aactgtaaca attggaacat ctggtcgttc
    10501 tttcttttat tttttcaaaa tttttagaat gtggtatttt acgcaaacgt ttgaattctg
    10561 ataaaaattg gagaaattcg acaaaaaaac ttgaaaaaaa cgaaggtaag cgttatgata
    10621 gaaaagaaga aatattggag gaagaacatg tcacatatta aatttgatta ttcaaaagtt
    10681 ttagacaaat ttgttgcacc acatgaagtg gaatacatgc aatcacaagt aacagcagca
    10741 gatgaattga tccgtaaagg aactggtgct ggtagcgact tcttgggatg gttggacctt
    10801 cctgaaaaat acgaccgcga agaatttgac cgcatcttga aagctgctga gcaaatcaag
    10861 tcagacagcg atgttttggt tgtgatcggt attggtggat cttaccttgg tgcaaaagca
    10921 gcaatcgact tcttgaatca ccattttgct aacttgcaaa caaaagaaga acgcaaagct
    10981 ccacaaatcc tttacgcagg aaactcaatc tcatctactt accttgctga cttggtagag
    11041 tatgttgcag acaaagactt ctcagtaaac gtaatttcta aatcaggtac aacaactgaa
    11101 ccagcgattg ctttccgtgt ctttaaagaa ctcttggtta agaaatacgg tcaagaagaa
    11161 gctaacaaac gtatctatgc aacaactgac cgccaaaagg gtgctgttaa ggttgaagca
    11221 gacgctaacg gttggggaac atttgttgtt ccagatgata tcggtggacg cttctcagta
    11281 ttgacagccg ttggtttgct tccaatcgca gcatcaggag ctgacataaa agctcttatg
    11341 gaaggtgcga atgcagctcg caaagactac acttcagaca aaatctctga aaacgaagct
    11401 taccaatacg cagctgttcg taacatcctt tatcgtaaag gctatgcaac tgagatcttg
    11461 gtaaactatg agccatcact tcaatacttc tcagaatggt ggaaacaatt ggctggtgaa
    11521 tcagaaggaa aagaccaaaa aggtatctac ccaacttcag ccaacttctc aactgacttg
    11581 cactcacttg gtcaatttat ccaagaagga actcgtatca tgtttgaaac agttgtccgt
    11641 gttgacaaac ctcgtaaaaa cgtgcttatt cctactttgg aagaagacct tgacggactt
    11701 ggttaccttc aaggaaaaga cgttgacttt gtaaacaaaa aagcaactga cggtgttctt
    11761 cttgcccaca cagatggtga tgtaccaaac atgtatgtga ctcttccaga gcaagacgct
    11821 ttcactcttg gttacactat ctacttcttc gaattggcaa ttgccctttc aggttacttg
    11881 aatgctatca acccatttga ccaaccaggt gttgaagctt ataaacgtaa catgtttgcc
    11941 cttcttggaa aaccaggatt tgaagaattg agcaaagaac ttaacgcacg tctataatag
    12001 aagaaaagag tggtttgccc actcttttta ctctctttat ccatagaaat tggactcagc
    12061 caagacttgt gatataatat agaaagcaaa aaggcagacg cctagataat aggagaaact
    12121 atgtcaaaag atatccgcgt acgttacgca ccaagtccaa caggactact acacatagga
    12181 aatgctcgta cagcattgtt taattacttg tatgcgcgcc atcatggtgg aacatttctc
    12241 atccgtatcg aagatactga ccgtaaacgc catgtcgagg atggtgaacg ttcacaactt
    12301 gaaaaccttc gctggttagg catggattgg gatgaaagtc cagaatcaca tgagaattat
    12361 cgccagtctg agcgtttgga cttgtatcaa aaatacatcg accaactatt agctgaagga
    12421 aaagcctaca aatcttacgt tacagaagaa gagttggcag ctgaacgtga acgtcaagaa
    12481 gtagctggcg aaacaccacg ctacatcaat gaataccttg gtatgagtga agaagaaaaa
    12541 gcagcttaca tcgcagaacg tgaagcagca gggatcatcc caactgttcg tttggctgtc
    12601 aatgagtcag gtatctacaa gtggcatgat atggtcaaag gcgatatcga atttgaaggt
    12661 ggcaatatcg gtggtgactg ggttatccaa aagaaagacg gttacccaac ttacaacttt
    12721 gccgttgtta tcgatgacca cgatatgcaa atctctcatg ttatccgtgg agatgaccat
    12781 attgctaata caccaaaaca gcttatggtc tatgaagctc ttggttggga agctccagag
    12841 ttcggtcaca tgaccttgat tatcaactct gagactggta agaagttatc taaacgtgat
    12901 actaatacac ttcaatttat cgaagattac cgaaagaaag gttaccttcc agaagcagtc
    12961 tttaatttta ttgctcttct tggttggaac ccaggtggtg aagatgagat tttctctcgt
    13021 gaagaactca ttaaactttt tgatgaaaac cgcctcagca agtcaccagc agcctttgat
    13081 cagaaaaaac tagactggat gagcaatgat tatatcaaga atgcagacct tgaaaccatc
    13141 tttgaaatgg caaaaccatt cttagaggaa gcaggccgtt tgactgacaa ggctgaaaaa
    13201 ttagttgagc tctataaacc acaaatgaaa tcagtagatg agattatccc attgacagat
    13261 cttttcttct cagatttccc agaattgaca gaagcagagc gcgaagtcat gacgggtgaa
    13321 acagttccaa cagttcttga agcattcaaa gcaaaacttg aagcgatgac agatgataaa
    13381 tttgtgacag aaaatatctt cccacaaatt aaagcagttc aaaaagaaac aggtattaaa
    13441 gggaaaaatc ttttcatgcc tattcgtatc gcagtttcag gcgaaatgca tgggccagaa
    13501 ttaccagata caattttctt gcttggacgt gaaaaatcaa ttcagcatat cgaaaacatg
    13561 ctaaaagaaa tctctaaata aagaggatac aataatggac atctgggaaa agatgtacga
    13621 agaagcacag aaactataca atccacatga agtatcagac tttgtttatg ccaatcatgt
    13681 tgtagctgca gtagaagcag aagatggaca aatatttaca ggattctgta tggagggaac
    13741 ctgtggtgtt ttccatctct gcgcagaacg ggcggccctc ttcaatacgt accaattttc
    13801 aggacaaact aaggttaaga aagtattagc ctttcgagac aaaccacctt atggtggaag
    13861 ttcagccatg ccttgcggtg cttgtagaga attcctttta gagcttaatg ctgaaaataa
    13921 agatgcagaa ttcatgatgg actataatat aagaaaaaca gttaaagtcg cagaactaat
    13981 cccttattgg tggggagaag aacgtgcttc taagtttaat gagcgataga agagtcagta
    14041 taattctggc tttttttact ataagttgaa aaaat
//
LOCUS       DAVAZT010000054        12692 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVAZT010000054 DAVAZT010000000
VERSION     DAVAZT010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12692
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.054"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(373..555)
                     /locus_tag="VQT45_001688"
     CDS             complement(373..555)
                     /locus_tag="VQT45_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359977.1"
                     /translation="MAVIFKNVLIEEKTEEEKQHILSILNGEYDLSDDVSCRLRRLNE
                     ESKRLEVFVKETNSLV"
     gene            complement(771..2003)
                     /locus_tag="VQT45_001689"
     CDS             complement(771..2003)
                     /locus_tag="VQT45_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET2359978.1"
                     /translation="MKIAVAGTGYVGLSIAILLAQHHQVVAVDIIPEKVELINKKKSP
                     IQDDYIEKYLAEKELNLVATLNAEEAYENADFIVIAAPTNYDPKKNFFDTSSVEAVIE
                     AVMKYNPDAIIIIKSTVPVGYTKSVRRKFLTDNIMFSPEFLRESKALYDNLYPSRIII
                     GTDKDDKDLVKSAEIFVKMLQEGAVKENIETLYMDFTEAEAVKLFANTYLALRVSYFN
                     ELDTYSEMKGLDTQAIIDGVCLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANYSDVPQ
                     EMITAIVQSNRTRKDYIADRILDLAGSYVGNDFYKPDKEKEIVVGIYRLTMKSNSDNF
                     RQSSIQGIMKRLKAKGVTIIIYEPTLESGTTFYGSQVVNDFEIFKKSSQVIVANRFDE
                     TLEDVRGKVYTRDIFKRD"
     gene            complement(2032..3102)
                     /gene="gla"
                     /locus_tag="VQT45_001690"
     CDS             complement(2032..3102)
                     /gene="gla"
                     /locus_tag="VQT45_001690"
                     /EC_number="5.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001214397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucuronate 4-epimerase Gla"
                     /protein_id="HET2359979.1"
                     /translation="MRGKTILITGVAGFIGSNLVRKLLELEGTMTIIGLDNLNDYYDI
                     ALKDYRLLQLNKLIQDYPEKNWIFIKGDIADKMLINKIFKSYHPQIVVNLAAQAGVRY
                     SITNPDVYIESNIVGFHNVLEACRHSYEIYDGGVEHLVYASSSSVYGGNKKIPFATED
                     KVDNPISLYAATKKTNELQAYAYSKIYNIPSTGLRFFTVYGPAGRPDMAYFGFTDKLR
                     SGSDIEIYNHGNCKRDFTYIDDIVEGIVRVMQSAPKKLVGSDNLPLAPYKVYNIGNSK
                     PENLLDFVDVLQQELIKAGVLPENYDFDSHKKLVPMQPGDVPVTYADTSDLERDFGFK
                     PKTSLREGLRKFAEWYKDYYNV"
     gene            complement(3170..4339)
                     /locus_tag="VQT45_001691"
     CDS             complement(3170..4339)
                     /locus_tag="VQT45_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HET2359980.1"
                     /translation="MRLSKKYWFALTSKFLLILLTLLSSIIINRGLGVEKKGDYAYVM
                     NLVEIFYILGGVGLGQAYSTFKRNHSNEYQNKFVFLTFIQGLLFGIIGLIIVLADVPI
                     DYGGVIIVLSSLSIMRTNLTMIAVIENSIKRNKIVLGVSVVYSVMLVLLLLFHLVSIE
                     MVFLVYAINEFLRIILFLYYYNMFPVFEHISIKEFFTIYKFGFLSMILTLLITFNYSI
                     DIIMLKQMSSSYNVGIYSVAVTFSNMFLMVPDSFKEILFGDSAKRTFEKNKAINAIKV
                     SFLFMILLIIGFLSFGEFAITLLYGSSYIKAFPITLVIFLGSLSMIFFKILQPIYISQ
                     GKQSVAIKILSVSALINISLNWYLIPNYQITGAAIASAISYTVCGLFFIIDYLRN"
     gene            complement(4525..5829)
                     /locus_tag="VQT45_001692"
     CDS             complement(4525..5829)
                     /locus_tag="VQT45_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HET2359981.1"
                     /translation="MKFSLQSNDIKNKIILLVGVVFSGTLILCSENNDVTIPLFSMIF
                     LSFMAMIIVKFNIFHPYVWYSSFFTIYSISYPLLYRMEYINYGYTKDLIFMQWLALAT
                     LLLTLPSKAIVLSERKINLNNNNYLLFLNNMNTFITTVAIIYLLGSGFRNKGEIYSGA
                     NIVIMLVFSLVYFMILIHTYQLFIQLSTKKWRLLNCNTNTAIVICLFSIVTGERDYMF
                     TLFILDVIILFYFHKIKRFYLVMLVPLAALLIPLSAVFKYTLLSGQVSSINTNNIWFD
                     LLDGEFVSASRNLQILILHNMGNYFEGRSFFNDIVRIFYNTGYSNQTWFMDTFFPNVH
                     STKYGFTLVGEGYVNGGYFGIVMIFMLTGFLMRFLYINAQRNIYGMLIYLYMIPIFIY
                     STRADFANILSPLLKYAILGTLVIVFINRMVLISPLDEMGGE"
     gene            complement(5946..7100)
                     /locus_tag="VQT45_001693"
     CDS             complement(5946..7100)
                     /locus_tag="VQT45_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET2359982.1"
                     /translation="MKVFIATEFRCTIYKNEIYLKPKAYFIYERYAKAFGEIVLCSRY
                     EKVESYPEGYHKANFINKFIPIEGLHQVLFGQNKNKIIEGMIDSDLIVVRIPSIIGSK
                     TADYALKIGKPYLTEIMGDAWDSYWYHSLKGKLLAPYIYAKTKSIVKNANYCIYVTEK
                     YLQDRYPNIKSNIVASNVNITSVENRSLKSRLYKLKKFNPQKISIMTTASVNVRAKGH
                     RFVLEAMKRLEIQGILLDYYLAGDGDQSFLKKKAEELGVANRIHFLGELTTSQIYEYL
                     DKVDLYIQPSLQEGLPRAVIEAMSRACPCIGSNKAGIPELLGPHCLFTPSSSQAIAGS
                     IIDFISMDKEKMVIKQFEFSKKFLSSVLNKRRSDYFAQIRRELNNSDGLD"
     gene            complement(7097..7648)
                     /locus_tag="VQT45_001694"
     CDS             complement(7097..7648)
                     /locus_tag="VQT45_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HET2359983.1"
                     /translation="MNRIIKNIVGLLRANICLILLKVCRNKDLTFHYFLKFGKNVTVE
                     QESNAKLILGKKIRVNAGGVLKVRKGAKLKISDDVFLSNNCMIACRKYIDIKSGVKCG
                     PGVLIYDHDYDVSVPGGLKAKKFKTAPVMIGENVWIGANSIVLKGVSIGENSVVAAGS
                     VVTKDIPADTIFIQKRLSREMKL"
     gene            complement(7641..8777)
                     /locus_tag="VQT45_001695"
     CDS             complement(7641..8777)
                     /locus_tag="VQT45_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001053205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET2359984.1"
                     /translation="MNLQKKKIMLITNHDDDIYCFRKEVIESLVEYGYEVLVSCPYGD
                     KIELMKSIQFEYEDITIDRRGINPLKDIRLFLSYIRLLRKYRPDVVLTYTVKPNVYAS
                     LAATILGIKYINNVTGLGSVLTMGSCVRSLVLLLFRISFRKSNCVFFQNEYNMKMLKT
                     LGLILGDSKLIPGSGVNIEKYPVQQYPNGGNGIQGETIVFNFIGRILKEKGIDTYLAA
                     AQIIKSRYPKTEFNIIGFIEPTESNYELKICDLEKKGIVYYLGQQKDVIPHITRSHAI
                     IHPSVYGEGMSNVLLENASSGRVLITTDNPGCKEIVKDRETGYIFQGGNVEELVSILE
                     VFLGLENEKRKEMGLQGRMYIEQYFSRQIIIDAYLDKIKGALDE"
     gene            complement(8918..9583)
                     /gene="cpsD"
                     /locus_tag="VQT45_001696"
     CDS             complement(8918..9583)
                     /gene="cpsD"
                     /locus_tag="VQT45_001696"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase
                     CpsD"
                     /protein_id="HET2359985.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNTLCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSVNIAMSFARAGYKTLLFDGDIRNSVMSGFFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVVQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTPPIGIVI
                     DAAIITQKCDASILITATGEANKRDVQKAKQQLEQTGELFLGVVLNKLDISVDKYGVY
                     GRK"
     gene            complement(9593..10282)
                     /gene="cpsC"
                     /locus_tag="VQT45_001697"
     CDS             complement(9593..10282)
                     /gene="cpsC"
                     /locus_tag="VQT45_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HET2359986.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYLVNRNQGEKPGLTNQDLQAGAYLVKDYREIVLSQDVLEEVISDLKLD
                     LMPKGLANKIKVTVPVDTRIVSVSVSDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNTLIGFLAGVIGTSVIVLLELLDTRVKRPEDIENALQMTL
                     LGVVPNLGKLK"
     gene            complement(10291..11022)
                     /locus_tag="VQT45_001698"
     CDS             complement(10291..11022)
                     /locus_tag="VQT45_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase CpsB"
                     /protein_id="HET2359987.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYRQIHTGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVSKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKELFVDNPRKIIMDQLI"
     gene            complement(11024..12469)
                     /locus_tag="VQT45_001699"
     CDS             complement(11024..12469)
                     /locus_tag="VQT45_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET2359988.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLICFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLLFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSKIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADS
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLTDGDRDRGRNQQKVIVAIIQKLTST
                     EVLKNYSSILQGLQDSLQTNIPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLTVVKAAIQDVMEGR"
BASE COUNT         4282 a         2460 c         1673 g         4277 t
ORIGIN      
        1 aaactttgaa aacttcaaaa aacggatttt catcgctctg aacatcaaaa aagaaaggac
       61 gaaatttgtc ctttctcgag cttagctgac ttcaacccac tacagttgac aaagagccta
      121 aaaattcact tacttcatat tacatttagc atgaaatgaa ataagcgaat tctactttgt
      181 ttgcatacaa ttaaaaatca attcctaagg atgttttaaa taactgtgta aaaggcataa
      241 tttcaccatt tcttagtttt tcaatgctaa attacatagt aactggagag ctattagaaa
      301 tctctaactt cctcatagtt aaaaaatgac aatgagatac ttattgattt caattcatta
      361 acagaatacg aactagacaa gtgagttcgt ctccttaaca aacacttcca agcgtttact
      421 ttcctcattc agtcgtcgta atctacaact tacatcatca gataagtcat actcaccatt
      481 tagaatagat agaatatgtt gtttttcttc ttcagtcttc tcttcaataa gcacattttt
      541 aaaaattact gccattatca gcacctcact tcgaaggaat atatgcaact atatcctatt
      601 aagtcaatct ctactgacaa aagaagtata tttacttcac taagtgcgag cgagaatata
      661 gaaatatctt tattgtttta gatgagttgt cgctatcctc cagctagttt ttaactattc
      721 tatcattcaa atgatataga ttattaggga ctagaaatat acaaattgat ttaatctctc
      781 ttaaaaatat ccctagtata aactttaccc ctcacatctt ctaaagtctc atcaaaacga
      841 tttgcaacaa tcacttgact agatttctta aatatttcaa aatcattaac tacttgacta
      901 ccatagaaag tagtaccact ttcaagagtt ggttcgtaaa taataatagt aacacctttt
      961 gctttcaaac gcttcataat accttgaata gaagattgtc taaaattatc tgaattactt
     1021 ttcattgtta aacgataaat tcctacaaca atctcttttt ctttatctgg tttatagaaa
     1081 tcattgccta cataagatcc agcaagatct aaaatacgat ctgcaatata atcttttctt
     1141 gtccgattac tttgtactat agctgttatc atttcttgtg gaacgtcaga ataatttgca
     1201 agaagttgct tggtatcttt aggaagacag taacccccat aaccaaaaga aggattattg
     1261 tagtgagaac ctattctcgg atctaaacaa actccatcaa taatcgcttg agtatctagt
     1321 cctttcatct cagaataagt atctaactcg ttaaaatagg aaacccggag ggcaagatag
     1381 gtattagcaa aaagttttac tgcttcagct tctgtaaaat ccatatacaa tgtttcaata
     1441 ttttctttca ctgcaccttc ctgaagcatt tttacaaaaa tttcagcaga ctttaccaaa
     1501 tctttatcat ctttatctgt acctataata attcgactcg gatataggtt atcatataac
     1561 gcttttgact cccgtaaaaa ctcaggacta aacataatat tgtctgtaag aaatttcctc
     1621 cgtactgact ttgtatatcc aacaggaaca gtacttttaa ttattataat tgcatcagga
     1681 ttatatttca taactgcttc aatgacagcc tcgactgaag atgtatcgaa aaaatttttt
     1741 ttcggatcat aattagttgg agccgcaata actataaaat ccgcattctc atatgcttcc
     1801 tctgcattca atgtagctac gagattcaat tctttttccg cgagatattt ttctatataa
     1861 tcgtcttgga taggggactt ctttttattg attaactcaa ctttctcagg aatgatatct
     1921 acggcaacaa cttgatgatg ttgagccagt aagattgcaa tagataatcc aacatatcct
     1981 gtacctgcta ctgctatttt cataattttt tcctttctca aaacactctc gttatacatt
     2041 atagtagtct ttataccact ctgcaaactt tctcaaacct tctcgtaaag aagtttttgg
     2101 tttaaaacca aaatctctct ctaaatcact tgtatctgca taagtaacag gaacatcgcc
     2161 tggttgcata ggaactaatt ttttatgact atcaaaatca taattttccg gcaaaactcc
     2221 tgccttgatt agctcctgtt gaagaacatc cacaaaatct aacaaatttt cgggtttact
     2281 attcccaata ttgtacactt tatatggggc taacggtaaa ttatcagatc ccactagttt
     2341 cttcggagct gattgcatga cccttactat cccctcaacg atatcatcta tataagtaaa
     2401 atctcgttta caattaccat gattataaat ctcaatatcg gaaccacttc gcaatttatc
     2461 tgtaaatcca aaataggcca tatctgggcg cccagcagga ccataaactg taaaaaagcg
     2521 taagcctgtc gaaggaatat tgtaaatctt tgaataagca tacgcttgaa gttcatttgt
     2581 ttttttagtc gcagcatata gtgaaatagg attgtctacc ttatcttctg ttgcaaacgg
     2641 gattttttta tttccaccat ataccgatga ggacgatgca taaactaagt gttccacacc
     2701 accatcatat atctcatacg aatgacgaca agcttccaac acattatgaa agccaacgat
     2761 attactttct atatatacat ctggatttgt aatggagtag cgtactcctg cctgggcagc
     2821 tagattaaca acaatctgag gatgataact cttaaaaatc ttattaataa gcattttatc
     2881 tgcaatatca cccttgataa atatccagtt tttttctgga taatcctgaa ttagcttatt
     2941 aagttgaagc aatcgataat ctttaagtgc aatatcatag taatcattca aattgtccaa
     3001 accaatgatt gtcatcgttc cttctaattc caataatttc ctaaccagat ttgatccaat
     3061 aaaaccagct actcctgtaa ttagaattgt ttttcctctc atatcataat acctcttgtt
     3121 atttttatat tttcgtccac taatacacat tctttaacaa ctattataat caatttctaa
     3181 gataatctat aataaaaaac aaaccacata cagtataaga gattgctgat gctatcgcag
     3241 ctcctgtaat ttggtagtta ggaattaagt accagtttaa acttatattt atcaaagccg
     3301 acacagataa aatttttata gctacactct gtttaccctg agatatataa attggttgta
     3361 aaattttaaa gaaaatcatc gataagcttc ctaaaaaaat gactaatgtt ataggaaatg
     3421 cctttatata actggaacca taaaggagcg taatcgcaaa ttctccaaaa gaaagaaatc
     3481 caataattaa taaaatcata aatagaaatg atacttttat tgcatttatt gctttatttt
     3541 tctcaaaagt tcttttagcc gaatcaccaa ataaaatctc tttaaatgag tctggaacca
     3601 tcaaaaacat attagaaaac gtaactgcga cactgtatat acctacatta taactactag
     3661 acatttgctt caacattatg atatcaatac tataattaaa tgtaattaat agagtaagaa
     3721 tcatagaaag aaatccaaac ttatatatag tgaaaaattc tttaatacta atatgttcaa
     3781 aaactgggaa catattgtaa tagtataaaa ataaaatgat acgtaaaaat tcattaatag
     3841 catataccaa aaataccatc tctatagaaa ctaaatgaaa tagtaacaac aatactagca
     3901 taacggaata tactacgctt actcctaata caatcttatt cctctttata ctattttcta
     3961 ttactgcaat catagtaaga tttgttctca taatagatag actggacaaa actattatta
     4021 ccccaccata atctatcgga acatcagcta aaactattat taaacctatt attccaaaca
     4081 ataatccttg aataaaagtt aaaaaaacaa atttattctg atactcatta gaatgattcc
     4141 ttttaaaggt cgagtaagcc tgacctaaac caactccacc taaaatataa aaaatttcta
     4201 ctaagttcat tacataggca taatctcctt ttttttcaac acctaatccc ctattaatta
     4261 taattgagga taaaagtgtt aataagatta acaaaaattt actcgttaaa gcaaaccaat
     4321 atttcttaga tagtctcact tattttctcc gtatgttaaa ttttataaca gtaaatttaa
     4381 aattatagta tattgaaata gaatatgaac aaaacgatta gggaatttaa agtaatttat
     4441 aaaaattctt tagaagctgc attgtactac tccaacttca aaccactata gtatcaaaaa
     4501 gtatacccca cctttttaaa taaactactc accacccatt tcatccaatg gtgatatcaa
     4561 caccattcta ttgataaaaa caataaccaa tgttcccaat atagcatatt taagtaatgg
     4621 agataatatg ttagcaaaat cagcacgagt agaataaata aaaataggta tcatatacag
     4681 atatatcagc atcccgtata tatttctttg agcgtttata taaagaaatc tcatcaaaaa
     4741 gcctgttagc ataaaaatca ttacaattcc aaagtatcct ccattcacat atccctctcc
     4801 cacaagagta aaaccatatt tggttgaatg tacgtttgga aaaaaggtgt ccataaacca
     4861 agtttgatta gaataccccg tattataaaa aattcttact atgtcattaa aaaaagaacg
     4921 accttcgaaa taattgccca tattatgtaa tatcagaatc tgtaaattac gactagctga
     4981 tacaaactca ccatctagca aatcaaacca aatattattt gtatttatag atgaaacttg
     5041 cccacttaat aaagtatatt taaaaactgc agataacgga atcagtagtg ccgcaagcgg
     5101 aactaacatt acaagataaa aacgttttat tttgtgaaag taaaataata taatcacatc
     5161 aaggatgaat aaagtaaaca tataatctct ttcccctgta acgatagaga agagacagat
     5221 aactatcgct gtgttagtat tacaatttag tagtctccat tttttagtac tcaactgtat
     5281 aaatagctga tatgtatgaa tgagaatcat aaaataaacc aaagaaaata ctaacattat
     5341 cacaatattg gcacctgaat atatttcccc tttatttcta aaaccacttc ctaatagata
     5401 tataattgct actgttgtga taaacgtatt catattattg agaaataata aatagttatt
     5461 gttatttagg tttattttcc tttcgcttaa cacaatggct ttagaaggta gagttaacaa
     5521 caaagttgcc aaagccagcc attgcatgaa aatcaaatct tttgtataac catagtttat
     5581 atactccatt ctatagagta gcgggtaaga aatagaataa atagtaaaga agctactata
     5641 ccacacatag ggatgaaaaa tattaaattt cacaattatc attgccataa aacttaaaaa
     5701 aatcattgaa aataatggaa ttgtaacatc attattttca ctgcataaaa ttaaagtccc
     5761 tgaaaaaact acacctacta gaagtattat tttatttttt atatcatttg attgtagact
     5821 aaacttcatt tacttttttc ctttaactaa taatttaaac gtaatgcgta ttcaaaaatt
     5881 tgattggcta tgtagtcagt ttttatagca tatttaatat atcgaaacgg attttccatc
     5941 gcattttaat ctaaaccatc agaattattt aattctcttc taatttgagc aaaatagtca
     6001 cttctgcgtt tatttaatac actcgaaaga aatttttttg agaattcaaa ctgttttatc
     6061 accatctttt ccttatccat actaataaaa tctataatag atcccgcaat cgcttgtgaa
     6121 gaggatggag taaatagaca atgtggcccc agcaactctg gaattcctgc tttattagac
     6181 cctatacaag ggcaagcacg gctcatagct tcaattaccg cacgaggtaa cccttcttgt
     6241 aaacttggtt gtatatataa atcaacttta tccaaatact cataaatttg tgatgtagtc
     6301 aattccccta aaaaatggat tctattcgct actcccaatt cctctgcttt cttttttaag
     6361 aaactttgat caccatcacc tgctaaataa taatccaaca aaataccttg tatttctaat
     6421 ctcttcattg cttccaatac aaatctatgg cccttggctc gtacattcac agatgctgtt
     6481 gtcattattg aaattttttg aggattaaat tttttcaact tataaagacg gctcttcaaa
     6541 gatctattct ctacagaggt aatattaaca tttgaagcaa cgatattaga tttaatatta
     6601 ggatatctat cttgtaaata tttttctgtc acgtatatgc aataattagc gttttttaca
     6661 attgatttag ttttggcgta tatatatgga gctaataatt ttccctttaa actatgatac
     6721 cagtaagaat cccaagcatc ccccattatt tctgtcagat acggcttacc tatcttcaat
     6781 gcgtagtctg cagtttttga tccaattata gacggaatac gaacaactat taagtcgcta
     6841 tcaatcattc cttcaataat cttattttta ttttgaccaa atagaacctg atgtagacct
     6901 tctataggga taaatttatt aataaagttc gctttatgat atccttcagg gtatgattcc
     6961 accttctcat aacgactaca tagtacaatc tctccaaatg ctttagcata gcgctcataa
     7021 ataaaataag ctttcggttt taaatatatt tcatttttat agattgtaca tctaaattca
     7081 gtcgctataa atactttcat aatttcatct cccttgataa acgtttctga ataaatatag
     7141 tatcagctgg aatatccttt gttacaacac ttcctgctgc aaccacacta ttctcaccaa
     7201 tactcactcc cttcaagaca atgctgttag ctccaatcca aacattttct ccaatcataa
     7261 ctggggccgt cttaaatttt tttgctttca atccacctgg aacactaaca tcatagtcat
     7321 gatcatatat aagtactcca ggaccacatt ttactccaga tttaatatct atgtatttac
     7381 gacaagctat catacaatta ttactcaaaa atacatcatc agaaatcttg agttttgctc
     7441 cttttctaac tttcaatact cccccggcgt ttactctaat cttttttcct aagattaatt
     7501 tagcattaga ttcctgttcg acagttacat tctttccaaa ttttaaaaaa taatgaaaag
     7561 taagatcctt gtttcgacac acttttaata atatcaagca aatatttgca cgaagtaaac
     7621 caacaatatt ttttataatc ctattcatct aaagctcctt ttattttatc taaataagca
     7681 tctataataa tttgacgaga aaaatattgc tctatataca ttctcccttg aagtcccatc
     7741 tcttttcgtt tttcattttc tagacctaaa aaaacttcca atatagagac tagttcctca
     7801 acatttcccc cttgaaatat atagcctgtc tctctatctt taacaatttc tttgcaacct
     7861 ggattatctg tcgtaattaa aacacgtcct gaactagcgt tttctagtaa tacattgctc
     7921 attccttcac catacacact gggatggata attgcatggg aacgggtaat atgaggtatc
     7981 acatcttttt gttgtcccaa ataataaacg attccttttt tttctaagtc acaaatttta
     8041 agttcataat tactctctgt cggttctata aagccaataa tattaaactc tgttttggga
     8101 tatcgactct taataatttg ggcagcagcc agataagtat ctataccttt ttcttttaat
     8161 atcctaccaa taaaattaaa aacgattgtt tctccttgaa ttccatttcc accatttgga
     8221 tactgttgca caggatactt ttcaatgttc actcctgacc caggtatcag cttagagtca
     8281 cccaaaatca agccaagagt ttttaacatt ttcatattat attcattttg aaaaaaaaca
     8341 caatttgatt tcctaaaaga aattctaaac agtaataaca ccaggcttct tacacaagaa
     8401 cccattgtta agacactacc taaacctgtt acgttattta tatattttat tcctaaaatt
     8461 gttgcagcta ggctagcata tacatttggt ttcacggtat atgtcaagac tacatccggt
     8521 ctatattttc tcaataatct tatataacta agaaatagac gaatatcttt taaagggttt
     8581 attcctcttc tatcaatagt aatatcttca tactcaaatt gaatagactt catcaactct
     8641 atcttatctc cataaggaca tgacactagc acttcatacc catactcaac tagtgactct
     8701 ataacttctt ttcgaaaaca atagatatca tcgtcatgat tagttattaa cataattttt
     8761 ttcttttgta aattcatcaa aataatcttc ctaaaatata attaaccgct actccattat
     8821 cctttacaac tatcatttta aaaatagtaa ttttctataa gtaattgttt ccaaattgtg
     8881 acactttaaa attctataca catatagaac ttacaaacta tttacgaccg taaactccat
     8941 acttatcaac cgagatatcc aatttattta aaacaactcc caggaacagt tcccctgttt
     9001 gttctaattg ttgtttcgct ttttggacat cacgtttatt cgcctcacct gttgctgtta
     9061 tcaagatgga cgcatcacac ttttgagtga taattgccgc atcaataaca attccaatag
     9121 gtggtgtatc aacaatgata taatcaaaat atttacgcaa tgtttcaatc atatcattaa
     9181 aatttttact ttgtaacaag gctgtagggt ttggtgatac agatcccgat tgaactacaa
     9241 ataaattttc aatatttgta tcacataaac cgtgagataa atcagctgtc ccagataaaa
     9301 attctgttag ccctgtaatt ttttcacgag atttaaaaaa tcctgacata actgaatttc
     9361 gaatatcgcc atcgaacaaa agagttttat agcctgcacg cgcaaatgac attgctatat
     9421 ttacggaagt agttgttttt ccttcccccg gattaacaga agtaacggaa attactttta
     9481 gtttatctcc gctcaactgt atatttgtac acaaggtatt gtaatattct tctgccttct
     9541 taatgaactc cagttttttt tgtgctattt ctaatgtcgg catctctctc tcctatttca
     9601 acttacccaa gtttggtaca actcccaaaa gtgtcatctg cagtgcattt tcgatatctt
     9661 ccggacgttt cacacgagtg tccaaaagtt caagaagaac tataacacta gttccaatca
     9721 cccctgccaa aaaaccaatt agtgtattgc gtttaatatt tggcgaagac ggtgatatcg
     9781 ccggtcttgc ctcctccagt gttgtcacat cagaaacacg agtaatactg ataatttttt
     9841 gagcagctac ttctcttaaa gagttagcga tacggcttgc ctcttcagga actcgatcac
     9901 taactgaaac agagacaata cgggtatcaa ctggtactgt tactttaatt ttattagcca
     9961 aaccttttgg catcaaatct agtttcaaat cagaaataac ttcctccaaa acatcctgcg
    10021 ataggacaat ttcacgatag tctttaacca agtatgctcc tgcctgcaag tcttgattgg
    10081 ttaaaccagg cttctctccc tgattacggt taactagata aatccgagtc gtactagtaa
    10141 actcaggttt gataacaaaa gtactgtagg caaaagcaac tgaagaagtt ataattgcca
    10201 ctaataaaat gaccaacttt cttttccata aagctctgaa tagttgcaat acatcgattt
    10261 ccaaagtgtt ttgttccttc atattttctc ctaaattaat tgatccatta taatttttct
    10321 gggattatct acaaaaagtt ctttcgcttt tttcgctcca tatttcttag caatgatatc
    10381 atatgcctgt tgcatatatg gaggtctact gtctaaattg tgcatgtcac ttgcaactac
    10441 atgaactaaa tcacgttcca aaaaataccg agctctcttt ttcatgaatt tatatttttc
    10501 accaaagaac ttaggttttg aaacatgata actatttatc tgagtatagc accccatatc
    10561 aatcagttca cgaacacgtt tttcgttatt ctctaaagca tcataacgtt caatatgagc
    10621 aattactggc gtgattccca acatcaaaat attgctcaat cccgtatgaa tctgacgata
    10681 ggaagtatgc atgctaaact caatcaaggc ataacgacta tcattaaggg taggaatttc
    10741 ttttttttct agcttttcta gagcatccag agtatagtat atctctgcgc cataagcaat
    10801 gactaaatca tctgctactt cttttgcaat ttcccgaacc tgaagaaagt tttctgctat
    10861 cttctcttcc ggagtttcaa acatgccctt gcgacggtga gaggtagaga caatggttct
    10921 caccccctgc ctgtaggatt ctgccaagag agccttgctt tcctctcttg acttgggacc
    10981 atcatctaca tcaaagacga tgtgcgaatg gatgtctatc attttatcta ccctccatca
    11041 catcctgtat agctgcttta actacagtta aactactatc atctatttcc atcacataga
    11101 ggttactgtc tggcattgca taagaaggaa gatccatccg acctgtccct tttaaatctt
    11161 gagaatttac tttataattc cctccacttt ccaactgagt attcactaaa tctatcatag
    11221 tctcaatcgg tatatttgtt tgaagagaat cctgcaatcc ttgaagaata ctactatagt
    11281 ttttcaaaac ctctgtagaa gttaacttct gaataattgc tacaatgacc ttttgttggt
    11341 tgcgaccacg gtcacggtct ccatcggtta gtgagtagcg ttcacgtaca aaacctaaag
    11401 cttgctcaga gtctagatgg acattcccta ctgggaaatg gaacttccca tgtagagctg
    11461 aaaactcttg atcattatga acatctaccc ctcccaataa gtcaatcatt ttcaagaaag
    11521 aagtgaagtt caatcgcaca tagtaattga tatccactcc atagagattt tctaaggtgt
    11581 gaatggacga atcaactcca taaatgcccg catgggttaa tttatctttt tgattatttc
    11641 cactatctgc gattggtaca taggcatcac gtggcgttgt ggtcaagagg attttcttgg
    11701 tatctcgatt gacagtcatt aggatattga catctgatcg cgacaccgaa ctaataggac
    11761 cataggtgtc aattccacta acatagatat tgaaagactg attcttagac gtcttaggag
    11821 cctctacttt tttagtgaat cccttggtat aaatcttttt tatcttcgat gcgtagtctg
    11881 gatactctga ctcgatgata ttttcaaaga cactatttag gacaatggcc ttagtctccc
    11941 ctgcaatcaa actcttgtaa gctgccaagt aagacgaact ctggttgacc gtcaaatcgg
    12001 tattctgact tgacttgata tcagctagta gtttttgaat attttcatta tcagtcccag
    12061 tcggtgctgt cacactcgtc agttgcgtaa cattttcgat cttactatct gctaaaacag
    12121 cgacactgat tgaatattct gagtaattag aagtcgcatt taaacgattg gtcagtccaa
    12181 caaactgctg tactgcaaag agcgacactg agctgacaag gatagagaac agcaacagaa
    12241 aaatagtaaa cttttcagct tttttataga taatcaagag tagccctacc aaggcaacta
    12301 gtaggactaa cgcagttacc actaggttaa gatatctaaa agcaaggata ttgtacttaa
    12361 agattaagaa caataaaaaa caaattaaca ataaataaat agtcagcaaa acgatattaa
    12421 cacttcgctt cactttctgt gaacgtgatt ttttaaaacg tctactcatg attaacacct
    12481 ataccttgaa catcatacaa ttatatcact tttttacggt aatgtctaca cctttatttt
    12541 cactatctgc atctttaagt atcttagtag acttcccgcg aaccaaaaat atagtaaaat
    12601 gaaataagaa taggacaaat caatcaggac agtcaaatcg atttctaaca atgttttaga
    12661 atcagatgtg tactattcta gtttcaatat aa
//
LOCUS       DAVAZT010000055        12480 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVAZT010000055 DAVAZT010000000
VERSION     DAVAZT010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12480
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.055"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            298..558
                     /locus_tag="VQT45_001700"
     CDS             298..558
                     /locus_tag="VQT45_001700"
                     /inference="COORDINATES: protein motif:HMM:NF012235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2359989.1"
                     /translation="MSGGETKRVALAKIILKNPPLIFADELTASLDSTTSQGIMKLLL
                     GMKNKNRLIIIATHNPDIWNQADEVINLNQLLQSIYIFYILK"
     gene            complement(662..1132)
                     /locus_tag="VQT45_001701"
     CDS             complement(662..1132)
                     /locus_tag="VQT45_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET2359990.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQTLLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(1149..3422)
                     /locus_tag="VQT45_001702"
     CDS             complement(1149..3422)
                     /locus_tag="VQT45_001702"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HET2359991.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLASDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            3769..6870
                     /locus_tag="VQT45_001703"
     CDS             3769..6870
                     /locus_tag="VQT45_001703"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HET2359992.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQGVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRLAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEVREGAFYYIKGKVQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSDELEAKLNEIVMKT
                     IYR"
     gene            6952..7959
                     /gene="pfkA"
                     /locus_tag="VQT45_001704"
     CDS             6952..7959
                     /gene="pfkA"
                     /locus_tag="VQT45_001704"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HET2359993.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            8016..9521
                     /gene="pyk"
                     /locus_tag="VQT45_001705"
     CDS             8016..9521
                     /gene="pyk"
                     /locus_tag="VQT45_001705"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HET2359994.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(10253..10478)
                     /locus_tag="VQT45_001706"
                     /pseudo
     CDS             complement(10253..10478)
                     /locus_tag="VQT45_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            11326..12198
                     /locus_tag="VQT45_001707"
     CDS             11326..12198
                     /locus_tag="VQT45_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HET2359995.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            12211..12375
                     /locus_tag="VQT45_001708"
     CDS             12211..12375
                     /locus_tag="VQT45_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2359996.1"
                     /translation="MTVILGFLFLFLMTWWVISIVNSQKPRKNETFIGYIQRYDIDGN
                     GYQSLPCPQN"
     gene            complement(12344..12480)
                     /locus_tag="VQT45_001709"
                     /pseudo
     CDS             complement(12344..12480)
                     /locus_tag="VQT45_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT         3808 a         2173 c         2665 g         3834 t
ORIGIN      
        1 ttgttttgtc gcttttcatt ataggtcata tgggactttt tttctacaat aaaataggct
       61 ccataatatc tatagtggat ttacccacta caaatattat agaacccttt tttattgaca
      121 gtatcaggat atctttttca aatttttggt ttgttagata atgaaaatgt ttctatcaat
      181 ctagatttag gattaataaa tcgtaaatgt aattataaag aaaaagataa gttaaaaaaa
      241 gatgtattag caagagttgg tctaactcat attcatctat aacaaaagat atatgaattg
      301 tctggcggtg aaacaaaacg tgttgcttta gcgaaaatca ttcttaaaaa tccaccatta
      361 atattcgcgg atgagttgac tgcatcactc gattcgacga cttcacaagg aattatgaaa
      421 ttgttattag gtatgaaaaa taaaaatcgt ctaatcatca ttgcaactca taatcccgat
      481 atttggaatc aagcagatga agttataaat ttaaatcaat tattacagtc aatatatatc
      541 ttctatattt taaagtaatt ttatctgaat ccgttaagag actattgtcc caggctcttt
      601 ctgatgttaa agactttcta ccaggttttt taaaagcata attgttagtt gtagtcattt
      661 attattcttc aaagaaaaat ggtggggcga attttttcag ttcttcaaag cacttttgag
      721 cagtatctgc atcttcacag atgataagac agacatcatt accacaaagg gtagcgatag
      781 cgtcagggaa gctcaaagta tcaatgatag aaccaaagga ttgagccagt ccaggaaggg
      841 tttttagtag gacttggtgt tgaactgggc gcatccagac aagggcgtct tccatgtaga
      901 gttcgagacg tttttcccat tttgagatgg aaccattgtt aagaacataa taagcgctat
      961 cttcttcgcg gacttttgat aggttcatat ttttgatgtc gcgtgagagg gttgcctgag
     1021 ttacttgaat gtcgttctca gcaagaaggg tttgcaactc agcctgtgta tgaatcttgt
     1081 tttttgtgat aagagcgcgt ataagttggt ggcggtgttc tgatttattc ataataatgt
     1141 aactcctttt agcaaggtaa ggtaagcatg gactgagcga ggtcgacagt caagtggtag
     1201 tctgtattgt cacggatggt gatttcaaag tcagtagtat agaggactaa acggagagtg
     1261 tctccttctt ttagcttgta aatagttggc tgcagttcaa attgaacgtc catccattca
     1321 tctgcagtaa tatcctctac taacagtaaa tcatttctat tttgtaaatt aaggtaacct
     1381 tttgtcacga ctctttgtgc ctctggtcta aatggcaatt cacagagatt ttccaacatg
     1441 tgatagcgac cgttgtcaat ggttctagca cttaaaatag ctggataagg ttgtaggtat
     1501 ttcttttgcc caaattctag cagttgggca gataagagcc ccttgtttgt actggatttg
     1561 atacgaagat tgagctgagc gcgaccgttt aggtggagat ctttagtcac aggaaggtta
     1621 atagtaatct gattagcttt cccttgatag agctctgtat tgaaggtttg gtatgtctta
     1681 ccatagcgct caaaatcctt atctgggtac tggttttgaa tagcttgctc ttcttgacca
     1741 agtgagaagg tttcacagtt ttcttgccca ccgaagttat caagtgataa ccaagtctgt
     1801 ggagctgtat tgtcctgcca gataacagta ggaagttgaa agtctgtttc ctgtcctagt
     1861 aatttcttgg tcaataaggc atttatggac tcacggaagt caattgattg ccaattgttc
     1921 atgtaaacat gggcaccatt atggaaaaag agatgcttgt gtatatgagt aggaagagca
     1981 tggaacatct ggtaaacatg aagtggtttg acattccaat cctgagaacc atgagtaaag
     2041 acaacctctg cctttacttt atgggcattg agcagataat tgcggtcatg ccaaaactga
     2101 ttgtagtccc cagtttttcg gtctagttga gctttcactt tttctaagtc agcttggtga
     2161 gcttcattgc cacggatata gtcgctagcc aagagattac gagaataggt taactcagca
     2221 agggagtcaa agtcctcacc tggataacca cctgggctag tcaccagacc gttttcacgg
     2281 tagtagttgt accatgatga aattcctgcc tcggcaatga taacttctaa accatcgact
     2341 cctgtagtcg caagaccatt ggacatggta cctagatagg aaagtcccgt tgtagcaact
     2401 tttccgtttg accaatcagc cttgacttga cgctggcgcg tgtgatcagt aaaggcacgg
     2461 caacggccgt taagccaatc gatgacattt ttataagcct cgatttgctg gtagtctcca
     2521 ttagtcatga aacctgtcga gtctttggta ccaacacctg agacatagag attggcaaag
     2581 cctctcggaa ggaagtagtc gtttagtgta tagctagagt tgatgtgagt tagcttttcc
     2641 tcagcctctg ctataagctc agctttacct tggggttgga cgagatttag ttgaggtttc
     2701 tctagctcaa tcttgtgagg aagtttaacc tcaagctcgc cctccatctt gtagagagcc
     2761 ttgtcactag ccttgtcatt ggttccctga tgataagggc tggctgtcat gatggcaggg
     2821 atttttccat caaaacgagg gcgaataatg ctaaccttta ctaggtctga tagccctttt
     2881 tggtcagtat cgacacgaga ctcaacgtaa acgacttcac gaatgacatc ctggttagaa
     2941 aaagtagcca aactcttgcc gttaaagtag tggtagtcat tatcctccgg aataagacca
     3001 tcactaacaa gttggtcgat aagagtattt ccttttttgg tgcgagtatt gagtaactga
     3061 tagagatttt caatcaagtc accatatata atgggaaatc cagtttcttt acgaaaaacg
     3121 tcactatctt cgaagtcaac caaataagaa aagcctaaaa gttgaaaagc aacagtataa
     3181 aaaatatctg ctgtcagttc atcttctgat tgaaaaaatg tcagcaggtc tgttttttta
     3241 tcagctgcta ggatagaaag tgggtagttg gtgtcttgat aagtgaaaaa gaaacgacgt
     3301 aaaaaggttt caagtgagtc tttgtgattg gctgtatttt gtaaatcaaa gccacatttt
     3361 tttagttcag ataagacatt ttcttttgga aaattgatat aactatattg attaaaacgc
     3421 atagaacctc catatagaat gacagttaag gttattatat caaaaaaaaa gcagaaaggg
     3481 aattgttaac ttcaaaagga aataatccaa taaaaatgaa taaagtacta aattcaatat
     3541 agagaacaga gtaacaataa gaataaatag atagggtata aaagttctag gagatttata
     3601 ttatatgctt tctgttttta tatacaatat agtataaata taaaaatgat gacaaaaata
     3661 caaatgaata gaaaataaat tagtaagctg atgaaatttt tctcaagaga agccatttat
     3721 aggtgaaaat ggtataatat agtgagaagg atagaggaga agtgtaaatt gatcgcacaa
     3781 ctagatacaa aaacagtcta tagttttatg gaaagcgtca tttcgatcga aaagtatgtg
     3841 agagcagcta aagaatacgg ctacactcat ttggctatga tggatattga caatctttat
     3901 ggcgctttcg actttctaga gattacaaaa aaatacggca ttcatccttt gctagggctt
     3961 gaaatgacag tgtttgtaga tgatcaggga gtgaatttgc gctttttagc tctatctagt
     4021 gtgggctatc agcagttgat gaagctttcg acagccaaga tgcaggggga gaaaacttgg
     4081 tcagtcctgt cccagtacct ggaggatatc gcggtcattg tgccttattt tgatagagtt
     4141 gagtcgttag aactaggctg tgattactat ataggggttt atccagaaac actagcaagc
     4201 gaatttcatc atcctatctt acctctttat cgggtcaacg cttttgaaag cagggataga
     4261 gaagttcttc aagttttaac agcgattaaa gaaaatctac cgctcagaga agttcccttg
     4321 cgttcgagac aagatgtctt tatatcagca agttctttag agaaactatt ccaagagcgt
     4381 tttccgcaag ctttggacaa tttagaaaag cttatttcag gcatttctta cgacttggat
     4441 actagtctga aactgcctcg ttttaatcca gctagaccag cagtagagga gttgagagag
     4501 cgtgctgaac tggggcttgt tcagaagggg ttgactagta aagaatatca agatagacta
     4561 gaccaagaat tgtctgttat tcatgatatg ggctttgatg attatttctt ggttgtttgg
     4621 gatttgttgc gttttggacg atcgaatggc tattatatgg gaatgggaag gggttctgca
     4681 gtaggcagtt tggtttctta tgccttagac atcacgggga ttgacccagt agagaaaaat
     4741 ctgatttttg aacgctttct taatcgtgaa cgctatacca tgcctgatat tgatattgat
     4801 atcccagata tttatcgtcc agattttatc agatatgttg gtaataaata tggtagtaaa
     4861 catgcggcac aaatcgttac tttttcaacc tttggagcca agcaagctct tcgagatgtc
     4921 ttgaaacgct ttggtgtgcc agagtatgaa ttatctgcaa ttactaagaa aatcagtttt
     4981 cgtgacaatc ttaagtcggc ctatgagggc aatctccagt ttcgtcagca aatcaatagt
     5041 aagttagaat accaaaaagc ttttgagatt gcttgcaaga tagagggcta tccaaggcaa
     5101 acctctgtcc atgcggctgg tgttgtaatt agtgaccaag atttaaccaa ctacattcct
     5161 ctaaagtatg gtgatgaaat tccactgact cagtatgatg ctcatggagt tgaggctagc
     5221 ggacttttga agatggactt tctgggacta cgaaatttga cctttgtcca gaagatgcaa
     5281 gagttgcttg ctgaaacaga aggtattcat ctgaaaattg aagaaatcga tttagaagac
     5341 aaagaaacat tagctttatt tgcctctggt aatacaaaag gtatctttca atttgagcaa
     5401 ccaggtgcca ttcgtctgct taagcgtgtg caaccagtct gttttgaaga tgtcgtcgcg
     5461 actacttctc taaatcgacc gggtgctagt gactatatca ataattttgt ggcaagaaag
     5521 catgggcagg aagaagtgac tgttctggat ccagtactgg aggatatttt ggctccaacc
     5581 tacggcataa tgctctatca ggagcaggtt atgcaggttg cccagcgact tgccggattt
     5641 agtcttggga aagccgatat tttgcgtcgg gctatgggga aaaaggatgc ctctgccatg
     5701 catgagatga gggcttcctt tattcaaggt tcattagaag ctggtcatac tgtggaaaaa
     5761 gcagagcagg tctttgatgt tatggagaag tttgcaggtt atggttttaa caggtcacac
     5821 gcctatgcct actcagcctt ggccttccag ttggcttatt tcaaaacgca ttatccagcc
     5881 attttttatc aggtcatgtt aaattcttcc aacagtgatt acttaataga tgcacttgaa
     5941 gcaggttttg aagtagcctc tctatccatc aacaccattc cctatcacga taaaattgcc
     6001 aacaaggcca tctatctagg tttgaaatcc attaaaggag tcagtaatga tttagctctc
     6061 tggattattg aaaatagacc ttattctaac attgaagatt ttatagctaa attacctgag
     6121 aattatctga aacttcctct gctagaacct ttggtaaaag ttggtctttt cgattcattt
     6181 gaaaaaaatc gtcaaaaagt atttaataac ttagctaatc tatttgaatt tgtgaaagag
     6241 ttgggaagtt tgtttggaga tgctatttat agttggcagg aatcggaaga ttggacggaa
     6301 caagaaaaat tttatatgga acaagagctt ttagggatag gtgtcagcaa acatccacta
     6361 caagctattg caagtaaggc tatttacccg attaccccaa tcggaaattt gtcagaaaat
     6421 agctatgcta ttatcttggt tgaagttcag aaaataaaag tgattcgtac caaaaagggt
     6481 gaaaatatgg ccttcttaca ggcagatgat agtaagaaaa aattggatgt tacactcttc
     6541 tcagatttat atcgacaggt tggtcaggaa gtaagagaag gagcattcta ctatatcaaa
     6601 gggaaagtcc aatcacgtga cggtcgtctg caaatgattg cacaagaaat aagagaagca
     6661 gttgctgaac gcttttggat acaggtgaaa aatcatgaat cggatcaaga aatttcacgt
     6721 attttagaac aatttaaagg cccaatccca gtcatcatcc ggtatgaaga ggaacagaaa
     6781 accatcgttt ctccccatca ttttgtagct aaatctgatg aattagaggc gaaattgaat
     6841 gaaatcgtta tgaaaacgat ttatcgctaa aaatacggaa aatagaagaa ttttaaaatc
     6901 aaatgtgata taatcaagaa gaatgttaaa agaaaaagga gcataaccaa tatgaaacgt
     6961 attgctgttt tgactagtgg tggagacgcc cctggtatga acgctgccat ccgtgcagtt
     7021 gttcgtcaag caatttcaga aggaatggaa gtgtttggta tctatgacgg atatgctggt
     7081 atggttgccg gtgaaattca tcccctagat gcagcttcag taggggacat catttctcgt
     7141 ggtggtactt tccttcactc agctcgttac ccagagttcg ctcaacttga agggcaactt
     7201 aaagggattg agcaattgaa aaaacacgga attgaaggtg tagttgttat cggtggtgac
     7261 ggatcttacc acggcgctat gcgtttgact gaacatggct tcccagctat tggtcttcca
     7321 ggtacaatcg ataacgatat cgttggtact gactttacaa tcggttttga cacagcggtt
     7381 actactgcca tggacgctat cgataagatt cgtgatacat catcaagtca ccgtcgtact
     7441 tttgtaatcg aagttatggg acgtaacgct ggtgatatcg ctctttgggc tggtattgca
     7501 actggtgctg atgaaatcat catccctgaa gcaggcttca agatggaaga tatcgtagca
     7561 agcatcaaag ctggttatga atgtggtaaa aaacacaata tcatcgtctt agctgaaggt
     7621 gtgatgtcag cggctgaatt tggtcaaaaa cttaaagaag ctggagatac aagcgacctt
     7681 cgtgtaacag aacttggaca tattcaacgt ggtggttctc caactgcgcg tgaccgtgtt
     7741 ttggcgtcac gtatgggtgc acatgctgtt aaacttctta aagaaggtat cggtggtgtt
     7801 gcggttggta ttcgtaacga aaaaatggtt gaaaatccaa ttcttggtac tgcagaagaa
     7861 ggggcattgt ttagccttac tgcagaaggt aagattgtgg ttaacaaccc gcacaaagcc
     7921 gatattgagc tatctagctt gaataagagc ttgtcataat ttacaattta gttaataaga
     7981 ccaaaaaggt catatataaa ggagtcacaa aaatcatgaa caaacgtgta aagatcgttg
     8041 caactttggg tcctgcggta gaaatccgtg gtggtaaaaa attcggtgag gacggatact
     8101 ggggtgaaaa acttgatgtt gaagcttcag ctaaaaacat tgctaaattg attgaagctg
     8161 gtgctaacac attccgattc aacttctcac acggcgacca ccaagaacaa ggtgagcgta
     8221 tggcaactgt taaacttgcg gaaaaaattg caggtaaaaa agttggtttc cttcttgata
     8281 caaaaggacc tgaaatccgt acagaattgt tcgaaggtga agctaaagaa tattcataca
     8341 aaactggtga aaaaattcgt gttgcaacta aacaaggaat caaatcaact cgtgaagtga
     8401 ttgcgttgaa cgttgctggt gctcttgata tctatgatga tgttgaagtt ggtcgtcaag
     8461 ttttggttga cgatggtaaa cttggtcttc gtgtggttgc taaagatgat gcaactcgtg
     8521 aatttgaagt tgaagttgaa aacgatggta tcatcgctaa acaaaaaggt gtgaacatcc
     8581 ctaacactaa aattcctttc ccagctcttg ctgaacgcga taacgacgat atccgtttcg
     8641 gtcttgaaca aggtatcaac ttcatcgcaa tttcattcgt acgtactgca aaagatgtga
     8701 acgaagttcg tgcaatctgt gaagaaactg gaaacggaca tgttcaatta ttcgctaaaa
     8761 tcgaaaacca acaaggtatc gataacttag acgaaatcat cgaagcagct gatggtatta
     8821 tgattgctcg tggtgatatg ggtatcgaag taccgttcga aatggttcca gtttatcaaa
     8881 aaatgattat caagaaagtc aatgctgcag gtaaagttgt tatcactgca acaaacatgc
     8941 ttgaaacaat gactgaaaaa ccacgtgcaa ctcgttcaga agtatcagac gtattcaacg
     9001 ctgttatcga cggaactgac gctacaatgc tgtcaggcga gtctgcaaac ggtaaatacc
     9061 cactcgagtc agtaactaca atggctacaa tcgacaagaa tgctcaagct cttcttaatg
     9121 aatacggacg tcttgattca gattcatttg agcgtaactc taagacagaa gtaatggctt
     9181 ctgctgttaa agatgctact agctcaatgg atatcaaatt ggtcgtaact cttactaaga
     9241 caggtcatac tgcacgtttg atttctaaat accgtccaaa tgctgacatc ttagcattga
     9301 catttgacga attgacagaa cgtggcttga tgttgaactg gggtgttatc ccaatgttga
     9361 cagatgctcc atcttcaact gacgatatgt tcgaaatcgc tgaacgtaaa gcggtagaag
     9421 caggtctcgt tgagtcaggc gatgatatcg ttatcgttgc tggtgtgcca gtaggagaag
     9481 ctgttcgcac aaacacaatg cgtatccgca cagtacgtta agaaaaatat aaaaacctat
     9541 catatccagc tttagagctt gtgtgatagg ctttttgtat agagggtaag aaataggcaa
     9601 aactttcata atggattgat actcttcgaa aatcaaattc aaaccacgtc agcgtcgcct
     9661 taccgtatat atgttactga cttcgtcagt tctatctaca acctcaaagc agtgctttga
     9721 gcaacctgcg gctagcttcc tagtttgctc tttgattttc attgagtatg aaataagata
     9781 tgcacaaatt gattaggaaa ttcaaatgaa tttctacaaa tgttttagca atcgtaatgt
     9841 acttgtctag attcgatctg atatattttc gatttaatga tatggtattt aaaacctcca
     9901 aagtagcttg ctccattctt ttacttacgt gagtgtagat gttatttact gttttagcgt
     9961 ttttgtgttc cactctaacc attatagcat tcttctcagc tagtgtacta aggagtgtgt
    10021 gcctgaaaat atgggaacta aggggctggt ttatcggttt ctctagttta gtatttgcct
    10081 tttgcaaagt gatgttaaat gcctttctct aaatttacat atcactattg tttaacaaaa
    10141 tctaatctac tttaggtcac ttattctttt tttgaaatgt agaatgaact ttttcaaagt
    10201 ttttcgaatc ttttaaaatc tgtttgtttt atatcgccat tctccccctt ttttaattct
    10261 ccctatatag cctgacaact ttcccgatgg tacgaatatg gttgctttcg tctaggtgga
    10321 tgtcggggta tttgggattg agttttttta aggtagcctt ggcggagttt cttgacatag
    10381 ttagcgccgt ctacttggaa gatgccgatg gtattatagt caatctgtgg ggtattcttg
    10441 ataaataggt agtcgctgtt tcttatcttt ggctccatgg acttgctgac gacataagcg
    10501 attgggtcgt agtcgtctgg gataatggaa actccataac taaatcgtcg tcctgcatcg
    10561 agcggctacc tgcagagata aactacctaa cacgagagta agtagtctgt ctgtagtcgt
    10621 ccagtctgat gatttttacg atatttcgtt tttctgctca tacagttgcc tctcggcata
    10681 ggtcagaact ttaccttgtc tgggtggtgc ccgttggtcg tagatagatt ggatatcgct
    10741 aggagaatcc ttttgaactg gaggaaagag ggtatcaatc aagctactga atactttagc
    10801 taagtcaaat atagtatttt tcttagtaga cctaaccctt ttttcataat ttccaatggt
    10861 gtttttactt ataccaatct tagtacccaa ttcttattga gtccaaccat tactagtcta
    10921 tattgtttta tagttgattg agtttggaat agtacgctgt agctgctaaa acatttctag
    10981 gaattaattt gactttccta atagagttgt tcatatctta tttcaatcta ctatgttttt
    11041 cacctctaac aatcgcaatc tcttctttat ccatgaatga aatcgctttc tatttttgta
    11101 agtaaagcat cacacgaaat ccacgaaaat gaaaaccttt gttgtgtttt cgtaaaaaat
    11161 ttgttgacag agcacgaaac gcctactata attaaatcaa gcttaaggaa ataacaaaaa
    11221 aacaaatcgg agggaaagac gatgaacaca ttaaatgaga aagtaatcaa tatctgtaaa
    11281 gcagtagtta aagaaacttt aatccaagac atttaggaga aagaaatgaa gaaatcaaga
    11341 aaattagcca cattaggaat ctgttcagcc ttgtttttag gcttggctgc ttgtcaacaa
    11401 caacatgcta cttctgaggg gacgaatcaa aggcaaagca gttcagcgaa agttccatgg
    11461 aaagcttcat acaccaacct aaacaaccag gtaagtacag aagaggtcaa atctctctta
    11521 tcagctcact tggatccaaa tagtgttgat gcatttttta atctcgttaa tgactataat
    11581 accattgtcg gctcaactgg cttatcagga gatttcactt cctttactca caccgaatac
    11641 gatgttgaga aaatcagtca tctctggaat caaaagaagg gcgatttcgt tgggaccaac
    11701 tgccgtatca atagttattg tcttttgaaa aattcagtca ccattccaaa gcttgaaaag
    11761 aatgaccaat tgcttttcct agataacgat gcgattgata aaggaaaggt ctttgattca
    11821 caagataagg aagagtttga tattctattt tcgagagttc caactgaggc aactacagat
    11881 gtcaaggttc acgctgaaaa gatggaaaca ttcttctcac aatttcaatt caatgaaaaa
    11941 gctcgaatgc tgtctgtagt cttgcacgac aatctggatg gcgagtatct gtttgtaggc
    12001 catgttgggg tcttagtacc tgctgatgac ggtttcttat ttgtagagaa attgactttc
    12061 gaagagccct accaagcgat taaatttgct agtaaggaag attgctacaa gtatttgggc
    12121 accaagtatg cggattatac aggcgaggga ctggctaagc cttttatcat ggataatgat
    12181 aagtgggtta aactttaata gtgttatgat atgacagtaa tcttaggatt tttatttcta
    12241 tttttgatga cttggtgggt tatttcaatc gttaatagcc agaaaccacg caaaaatgaa
    12301 acatttattg gctatatcca aagatacgat attgatggga atggctatca atcattaccg
    12361 tgtcctcaga actgagagga gttcttgaaa ccgtaaaacc gctttgaaca agagttactt
    12421 caacccattg gctccgacgg agtaagttgc tttcgtgaat accaaaatca gccgcaattt
//
LOCUS       DAVAZT010000056        12097 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVAZT010000056 DAVAZT010000000
VERSION     DAVAZT010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12097
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.056"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..138
                     /locus_tag="VQT45_001710"
     CDS             <1..138
                     /locus_tag="VQT45_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2359997.1"
                     /translation="RSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIINHELG
                     F"
     gene            330..2621
                     /gene="pcrA"
                     /locus_tag="VQT45_001711"
     CDS             330..2621
                     /gene="pcrA"
                     /locus_tag="VQT45_001711"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HET2359998.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTTYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            2664..3344
                     /gene="radC"
                     /locus_tag="VQT45_001712"
     CDS             2664..3344
                     /gene="radC"
                     /locus_tag="VQT45_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HET2359999.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3341..4030)
                     /locus_tag="VQT45_001713"
     CDS             complement(3341..4030)
                     /locus_tag="VQT45_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET2360000.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYNLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(4048..4689)
                     /locus_tag="VQT45_001714"
     CDS             complement(4048..4689)
                     /locus_tag="VQT45_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HET2360001.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(4772..4987)
                     /locus_tag="VQT45_001715"
     CDS             complement(4772..4987)
                     /locus_tag="VQT45_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET2360002.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(4995..5342)
                     /locus_tag="VQT45_001716"
     CDS             complement(4995..5342)
                     /locus_tag="VQT45_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HET2360003.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFSLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5347..6462)
                     /locus_tag="VQT45_001717"
     CDS             complement(5347..6462)
                     /locus_tag="VQT45_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET2360004.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6472..7431)
                     /locus_tag="VQT45_001718"
     CDS             complement(6472..7431)
                     /locus_tag="VQT45_001718"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET2360005.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(7544..8113)
                     /locus_tag="VQT45_001719"
     CDS             complement(7544..8113)
                     /locus_tag="VQT45_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HET2360006.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAEDYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8241..8912
                     /locus_tag="VQT45_001720"
     CDS             8241..8912
                     /locus_tag="VQT45_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HET2360007.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            8896..9714
                     /locus_tag="VQT45_001721"
     CDS             8896..9714
                     /locus_tag="VQT45_001721"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HET2360008.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            9711..10607
                     /locus_tag="VQT45_001722"
     CDS             9711..10607
                     /locus_tag="VQT45_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET2360009.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            10651..11625
                     /gene="pta"
                     /locus_tag="VQT45_001723"
     CDS             10651..11625
                     /gene="pta"
                     /locus_tag="VQT45_001723"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HET2360010.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(11941..>12097)
                     /locus_tag="VQT45_001724"
     CDS             complement(11941..>12097)
                     /locus_tag="VQT45_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2360011.1"
                     /translation="YSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFTALNIKKERT
                     KFVLSRA"
BASE COUNT         3524 a         2307 c         2603 g         3663 t
ORIGIN      
        1 agaagcaagg ttgagaacat ctttgccaaa gtaaaaacgt ttaaaatgtt ttcaacaacc
       61 tatcgaaatc atcgtaaacg cttcggatta cgaatgaatt tgattgctgg cattatcaat
      121 catgaactag gattctagtt ttgcaggaag tctattgagg tattgagcta gtttatgaaa
      181 aaattgggtg aaaaagtcga gtgttttaga aacccacagt gtagtattct agtttcaatc
      241 cactatattt tgctactccc cgtaaagttt ctattttccc tgatttctga tataatagaa
      301 atattgactt caagagtaag gaagagaaga tgaacgcatt attaaatgga atgaatgacc
      361 gtcaggctga ggcggtgcaa acgacagaag gtcccttgct aatcatggca ggagctggtt
      421 ctggaaagac tcgtgtttta acccaccgta tcgcttattt gattgatgaa aagctggtca
      481 atccttggaa tatcttggcc attaccttta ccaacaaggc tgcgcgtgag atgaaagagc
      541 gtgcttatag cctcaatcca gctactcagg actgtctgat tgcgaccttc cactccatgt
      601 gtgtgcgtat tttgcgtcgc gatgcggacc atattggcta caatcgtaat tttacaattg
      661 tggatcctgg tgaacagcga acgctcatga aacgtattct caaacagttg aacttggatc
      721 ctaaaaaatg gaatgaacga actattttgg ggaccatttc caatgctaag aatgatttga
      781 ttgatgatgt tgcttatgct gctcaagctg gcgatatgta tacgcaaatt gtggcccagt
      841 gttatacaac ctatcaaaaa gaacttcgtc agtctgaatc cgttgacttt gatgatttga
      901 ttatgctgac cttgcgtctc tttgatcaaa atcctgatgt tttgacctac taccagcaaa
      961 aattccaata catccacgtt gatgagtacc aagataccaa ccacgctcag taccaattgg
     1021 tcaaactctt ggcttcccgt tttaaaaata tctgtgtggt tggggatgcg gaccagtcta
     1081 tctacggttg gcgtggtgct gatatgcaga atatcttgga ctttgaaaag gattacccca
     1141 aagctaaggt tgttttgttg gaggaaaatt accgctcaac caaaaccatt ctccaagcgg
     1201 ccaacgaggt tattaaaaat aataaaaatc gccgtcctaa aaatctctgg actcaaaacg
     1261 ctgatgggga gcaaatcgtt tactatcgtg ctgatgatga gctggatgag gctgtatttg
     1321 tagccagaac catcgatgaa cttagtcgca gtcaaaactt ccttcataag gattttgcag
     1381 ttctctatcg gactaatgcc cagtcccgta caattgagga agccctgctc aagtctaaca
     1441 ttccttatac catggttggc ggaaccaaat tctacagccg taaggaaatt cgcgatatta
     1501 ttgcttatct caaccttatt gctaatttga gtgacaacat tagttttgag cgtattatca
     1561 acgagcctaa acgtggaatt ggtctaggta cagttgagaa aatccgtgat tttgcaaatt
     1621 tgcaaaatat gtctatgctg gatgcttctg ctaatattat gttgtctggt atcaagggta
     1681 aggcagccca atctatctgg gattttgcca atatgatgct tgatttgcgg gagcagctag
     1741 accacttaag cattacagag ttggttgagt ccgtcctaga aaaaacaggt tatgtcgata
     1801 ttcttaacgc ccaagcgact ctagaaagca aggcaagggt tgaaaatatc gaagagtttc
     1861 tttctgttac gaagaacttt gatgacacca ctgatgtgac agaagaggaa actggtctgg
     1921 acaaactgag tcgtttctta aatgacttgg ctttgattgc cgacacagat tcaggtagtc
     1981 aggagacatc agaagtgacc ttgatgaccc tgcatgctgc caaaggtctc gaatttccag
     2041 ttgtcttttt gattgggatg gaagaaaatg tctttccact tagtcgtgcg actgaagatc
     2101 cagatgaatt agaagaagag cgccgtctag cctatgtagg tatcacgcgt gcagagaaaa
     2161 ttctctatct gaccaatgcc aactcacgct tgctttttgg tcgtaccaat tataaccgtc
     2221 cgactcgttt tattaacgaa atcagttcag acttgcttga gtatcaaggt ctggctcgtc
     2281 ctgcaaatac aagctttaag gcatcatata gcagtggtag tatttccttt ggtcaaggta
     2341 tgagtttggc tcaggctctt caagaccgta aacgcggtgc tgccccaaaa tcgatccagt
     2401 caagcggtct tccatttggt caatttacag ctggcgcaaa atcagcatct agcgaggcaa
     2461 attggtccat tggtgacatt gctctccaca agaaatgggg agagggaact gttctggaag
     2521 tttcaggtag cggtgctagg caggaattga aaatcaattt cccagaagta ggtttgaaaa
     2581 aacttttagc cagtgtggct ccaattgaga aaaaaatcta attttccatc cttctcacga
     2641 ataataaagt gaggaggatt tttatgtaca gtatttcatt ccaagaagat tcactattac
     2701 caagagaaag gctggccaag gaaggagttg aagcgcttag taaccaagag ttgctagcta
     2761 ttttactcag gacaggaaca cgtcaagcta gcgtttttga aattgcccaa aaagtcttga
     2821 acaatctttc aagcctaacg gatttgaaaa aaatgaccct gcaggaattg cagagtttgt
     2881 ctggtattgg gcgtgttaag gccatagaat tacaagctat gattgaactg gggcatcgta
     2941 ttcacaaaca cgagactctt gaaatggaaa gtattctcag cagtcaaaag ttggccaaga
     3001 agatgcagca ggaattaggg gataaaaaac aagagcacct ggtggcactc tatctcaata
     3061 ctcaaaatca aatcatccat cagcagacca tttttatcgg ttctgtaact cgtagtatcg
     3121 ctgaaccgcg agagattctt cactatgcaa tcaagcatat ggcgacttct cttatcttgg
     3181 tccacaatca tccttcagga gcggtagcgc ctagccaaaa tgatgatcat gtcactaaac
     3241 ttgttaaaga agcctgcgaa ttgatgggga ttgttctctt ggaccatttg attgtctctc
     3301 attctaatta ctttagttat cgtgaaaaga cagatttaat ctaaagttca ttaacgacat
     3361 agtcaaagag ttttttatct ttgggacgat tttcaaaaag aagttctgga tgccattgga
     3421 caccgagaaa ggcgacatca tccgtactca tgacagcctc aatgatacca tctttaggat
     3481 catgagccac aacttttaaa tttggtgcta agtccttgat gctctggtgg tggaaggagt
     3541 tgatatgaga gatttctcca tagatttctt ggagaacggt atctggttct gttaccaagc
     3601 gttgagttgt gtactcaaca gaagaatcct gccaatggtc ttcgatatct tggtacaaag
     3661 ttccacccat ggcaacgtta aagagttggg taccacggca gacagagaaa atgggctttt
     3721 tctgtttaat agcttccttg atgagggcca gttcgaagat atctctttga aggttatagt
     3781 catcgctatc aatggttttg ggttcgccat aaaattttgg atcgacattt tgcccacctg
     3841 tcaagatgag cttgtcaatc aaactgatat agtggcaggc catttcttga tcaccaatcg
     3901 gtaggatgat gggaatccct ccagcatctt taacgccttc aacaaagcct tttgctgcgt
     3961 agctcatcat gatgtcatca tctggatgag ctttttcgtt tcctgtaatc ccaataactg
     4021 gttttttcat aaaatgattt tcgctttcta atcctctttt cgcatgaagt agaggagggt
     4081 ttggagttca cttgtcaaat cgacatactg aacgaccacg tcttttggta aatgcagatg
     4141 gactggtgaa aaactgagaa ttcctttcac accagcatca accaagagat tagcaacctc
     4201 ttgtgacttg acgctgggaa cagttaggat agcagtcttc acatcagcat ccttgatttt
     4261 atccttgatc tgagaaatcc cgtaaatggg aatcccgtca ggagtttggg taccgacttc
     4321 aggatggtcg tctaggtcaa aggccatgat aatcttcatc ttgttacgtt cgtggaagcg
     4381 gtagtggaga agggcatggc ccatatttcc aataccaacc agcatgacat tggtaataga
     4441 gttgtcattg agcaaatcgg caaaaaatgt cattagtttt ttgacatcat agccaaaacc
     4501 acgacgacca agttcaccaa aataggaaaa atcacgacgt acggtcgctg aatcaatacc
     4561 gatagcctct gcaatttgct tagagttggc acgttcaatc ttttctgcat gaaatctctt
     4621 aaaaattcga tagtagagag agagtctttt tgctgtagct tttggaatag caaactgttt
     4681 atctttcaca aaatcacaac ctttctattc ttctatttta tagaaacatt gtgaaaaaat
     4741 caacaaaaat aagaaaaaac taagaaaaat cttagttttg atgtaaaaaa tctgcatgag
     4801 atagaaaacg gtagaggtct ccgaccagac cctgataaac tttttggccc ctaaaagtca
     4861 gagaagtcac ataaagtgta tctggtaagg ttacacatcc tgacaaagtc aacatgagag
     4921 cctcatgatc ctcatacttg agagtacgct ctacatgata gcagtcctta taggtcagtt
     4981 caaacatttt ggctctatct ttccgatttt gtaaagacac cacgttctac caagctatcc
     5041 atgaggaagt agaatttttc ctgatgaata tggtggtctt ctgatttgaa aatatcaact
     5101 agacgaaggc taaacttgtc agtgatattg attttagccc ctgtaagttc cttgttaatg
     5161 atgattttga gttggaagcc ttcaccgctg tttggcactt tttccaaaag gcgagtcagt
     5221 tcatagttac caaccttagt ttcaaaaaag gtgttatctt tgagggtgaa ttttttaaca
     5281 gaagggctaa gagtgtaatc gtaacgacaa ttttttaact gaatgatttt ttcaaatgcc
     5341 atatggctaa cctccgataa tttcttttaa ggtttttgcg agggtttgta ggtcttcaac
     5401 ggtattttgt ggcgacaaac tgatgcgaag ggattccttc aagcgttctg aatttgcgcc
     5461 atacatggct tcaagaacat ggctggattg gacaacgcct gcagtacagg ctgagccagt
     5521 agagattgaa attccagcta aatctagccg aaggagtaag aggtcatttt tctgaccagg
     5581 aaatccaata ttgagaacat aagggagatg atgttttcct ctattcaagt aatactgaat
     5641 gccctccagc tctgccagaa aggcggtttc tagattttgt acatgttgaa aatgttcttc
     5701 ttgtttttct aggtcttctt ttagggctgc aaccatgcct acgatagcag gcagattttc
     5761 agttcctgca cgttttttct gttcctggtc tccgccatgt agataggaat caaagtccat
     5821 gctagatgcg tagagaaaac cgattccctt aggaccatgg aatttgtggg cagaagcagt
     5881 gagaaaatca atgcccaatt cttctgaatg aattgggatt ttaccaatag cctgaactgc
     5941 atcaacatga taggcagcag ggtgttgctt gagtatttgg ccaatttcag cgatgggcag
     6001 taggtttcct gtctcattat tggcaaacat ggtagaaacc aaaatcgtat cgtcacgtaa
     6061 agccttttga atttgctggg ctgtgatttc ttgattttct ggctggataa tggttgcttc
     6121 aaacccaaag tgttgaacca agtaatcaat tgtttcaagg acagcatggt gctcgatggc
     6181 agttgtgatg atatgttttc cttgttcttg gtgacgaaga cagtagccaa tgatggtagt
     6241 attattgcct tcagtcccac cagaagtgaa aaagatatgt tgaggttttg tccttagtaa
     6301 ctgggctagt tcctgacggg cttctcgcaa gagtttgcca gcttgacgac catgaccatg
     6361 aatactagaa ggatttccgt gggtttcttg cataaccttg gtcatagctg aaatagcaac
     6421 tgctgacata ggagtcgttg cagcattgtc caaataaatc aaagaatcac cttatttctt
     6481 tttattgtag gcaaagagtg ggctgactgg ttttctttcg tgaatacgga cgatagcatc
     6541 accaattaac tcactagcag tgatgtagca tacattttta ggagtttttt cttttgttgc
     6601 tactgaatca gtcacaagaa tttctttaat attagtattg tcaagaagct cagcagctcc
     6661 ctcgacgaag agaccgtggc tagaaacagc ataaatttct gtagctcctt cacgttcaac
     6721 gattttagaa gcttcagaga aggtacgtcc tgtatttaaa atatcatcaa tcaagatagc
     6781 tttcttacct tcaacatcac caataatata accttcgtta cgagttgcat cgtcttgagg
     6841 gtagtcgata atggcgatag gagcatcaag atattcagcc aggctacgcg cacgtttgac
     6901 acctgaattt ttagggctaa cgacaacaac atctgaacca agcaatcctt tatcgcagta
     6961 atgttttgcg aataggggaa cagtgaaaag attatccact ggaatatcaa agaaaccttg
     7021 aacctgaacg gcatgcaaat caagagtcag gatacgatca actccagcct taaccagcat
     7081 attggcaact agttttgctg taagtggctc acgaggacaa gcaatgcggt cttgacgtgc
     7141 atagccaaaa tatggaagga caacgttgat actgtgggca cttgcacgca cacaagcatc
     7201 gaccatgatt aacaattcca ttaggtggtt gttgacaggg aaacttgttg attggatgat
     7261 gtaaacatca taaccacgga cactttcttc gatatttact tggatttctc cgtctgaaaa
     7321 ttgacgtgat gatagttttc caagtgggac accaacagct tgggcaattt tttgtgcaat
     7381 ctcttggtta gagttgagtg cgaaaagttt catgtttttt ctatctgaca ttatagaccg
     7441 tcctctgtaa actttataaa tcctagttat atttacctta catatatgaa ctgggatttg
     7501 tgtattttta tcttttctat tttaccaaaa aatggagatt atttcagcta tttttcatac
     7561 ttttgacaaa tcgaaccaat tttgaaggag ctttttggta ggaaatctga tttttctcta
     7621 aaaattgtcg gaaatcctgt ttgccttgct catgattttc cacttcaagc tccaattcgt
     7681 aatctgttat atcaaagtat cggctctgat ccagtgccat gagaccaata gctgttttca
     7741 tttcatagcg aagcgttgtt agacaaccaa gaacctgcca gttcttactt tggataccat
     7801 gtttcgccaa ttcatccagt actagtcctt gaggaagttc ttccttactc agatagtcct
     7861 cagcatcttt tagttgcaat ttttggttgt attccatgtt tccaacactc tgcgggactt
     7921 tgagtgtcaa ctcagcccag tcttcaaagg ttcgaatgcg catagcgact ttcttttctc
     7981 gcagttcaaa atcaggcgtg tcgatgtagt aatttgtttg aagaacagga gtgacacctg
     8041 tgaactggtc ttttagacga ttgtattcat cttttttcaa tagtgttttc aattcaattt
     8101 ctaaatgttt catttttctt accttttttt atcgttgaaa gcggatttat ggtataataa
     8161 gcattgtatt tattgtatat gaatctggag aaaaaatcaa agatattttt gacggataat
     8221 atgagaacaa gggagaatat atgaccttag aatgggaaga atttctagat ccttacattc
     8281 aagctgttgg tgagttaaag attaaacttc gtggtattcg taagcaatat cgtaagcaaa
     8341 ataagcattc tccaattgag tttgtgaccg gtcgagtcaa gccaattgag agcatcaaag
     8401 aaaaaatggc tcgtcgtggc attacttatg cgaccttgga acacgatttg caggatattg
     8461 ctggcttacg tgtgatggtt cagtttgtag atgacgtcaa ggaagtagtg gatattttgc
     8521 acaagcgtca ggatatgcga atcatacagg agcgagatta cattactcat agaaaagcat
     8581 caggctatcg ttcctatcat gtggtagtag aatatacggt tgataccatc aatggagcta
     8641 agactatttt ggcagaaatt caaattcgta ctttggccat gaatttctgg gcaacgatag
     8701 aacattctct caactacaag taccaagggg atttcccaga tgagattaag aagcgactgg
     8761 aaattacagc tagaatcgcc catcagttgg atgaagaaat gggtgaaatt cgtgatgata
     8821 tccaagaagc ccaggcactt tttgatcctt tgagtagaaa attaaatgac ggtgtaggaa
     8881 acagtgacga tacagatgaa gaatacaggt aaacgaattg atctgatagc caatagaaaa
     8941 ccgcagagtc aaagggtttt gtatgaattg cgagatcgtt tgaagagaaa tcagtttata
     9001 ctcaatgata ccaatccgga tattgtcatt tccattggcg gggatggtat gctcttgtcg
     9061 gcctttcata agtacgaaaa tcagcttgac aaggtccgct ttatcggtct tcatactgga
     9121 catttgggct tctatacaga ttatcgtgat tttgagttgg acaagctagt gactaatttg
     9181 cagctagata ctggggcaag ggtttcttac cctgttctga atgtgaaggt ctttcttgaa
     9241 aatggtgaag ttaagatttt cagagcactc aacgaagcca gcatccgcag gtctgatcga
     9301 accatggtgg cagatattgt aataaatggt gttccctttg aacgttttcg tggagacggg
     9361 ctaacagttt cgacaccgac tggtagtact gcctataaca agtctcttgg cggtgctgtt
     9421 ttacacccta ccattgaagc tttgcaatta acggaaattg ccagccttaa taatcgtgtt
     9481 tatcgaacac tgggctcttc cattattgtg cctaagaagg ataagattga acttattcca
     9541 acaagaaacg attatcatac tatttcggtt gacaatagcg tttattcttt ccgtaatatt
     9601 gagcgtattg agtatcaaat cgaccatcat aagattcact ttgtcgcgac tcctagccat
     9661 accagtttct ggaaccgtgt taaggatgcc tttatcggtg aggtggatga atgaggtttg
     9721 aatttatcgc agatgaacat gtcaaggtta agaccttttt aaaaaagcac gaggtttcta
     9781 agggattgct ggctaagatt aagtttcgag gtggagctat tctggtcaat aatcaaccgc
     9841 aaaatgcaac gtatctattg gacgttggag actacgttac cattgacatt cccgctgagg
     9901 aaggctttga aaccttggag gctattgagc atccattaga tattctctat gaggatgacc
     9961 actttctagt cttgaataaa ccctatggag tggcttctat tcctagtgtc aatcactcta
    10021 acaccattgc caattttatc aagggttact atgtcaagca aaattatgaa aatcagcagg
    10081 ttcacattgt taccagacta gatagggaca cttctggctt gatgctcttt gccaagcacg
    10141 gttatgccca tgcacgatta gacaagcagt tgcagaagaa atctatcgag aaacgctact
    10201 ttgctttggt taagggagat ggacatttgg agccagaagg ggaaattatt gctccgattg
    10261 cgcgtgatga agattccatt attaccagac gagtggctaa aggcggaaag tatgcccata
    10321 cttcatacaa gattgtagct tcttatggaa atattcactt ggtctatatt cacctgcaca
    10381 ctggtcgaac ccatcaaatc cgagtccatt tttctcatat cggttttcct ttgctgggag
    10441 atgatttgta tggtggtagt ctggaagatg gtattcaacg tcaggctctg cattgccatt
    10501 acctatcctt ttatcatcca tttttagagc aagacttgca gttagaaagt cccttgccgg
    10561 atgatttcag taaccttatt acccagttat caactaatac tctataaaaa ctgtctcaga
    10621 gtataattat tatcttaaag gagaaaactc atggaagttt ttgaaagtct caaagccaac
    10681 cttgttggta aaaatgctcg tatcgttctc cctgaagggg aagagcctcg tattcttcaa
    10741 gcaacaaaac gcttagtaaa agaaacagaa gtgattcctg ttttgcttgg aaatcctgaa
    10801 aaaattaaaa tttatcttga aattgaagga atcatggatg gttatgaggt catcgaccct
    10861 caacattatc ctcaatttga agaaatggtt tctgccttgg tggagcgtcg caagggcaaa
    10921 atgactgaag aagatgtacg caaggttttg gttgaagatg tcaactactt tggtgtgatg
    10981 ttggtttact tgggcttggt tgatggaatg gtgtcaggag cgattcactc aacagcttca
    11041 acagttcgtc cagctctaca aatcatcaaa actcgtccaa atgtaactcg tacttcagga
    11101 gccttcctca tggttcgtgg tacggaacgt tacctatttg gagactgtgc cattaacatc
    11161 aatccagatg cagaagcctt ggctgaaatt gccatcaact cagcaatcac agctaagatg
    11221 tttggcatcg aacctaaaat tgccatgttg agctattcta ctaaaggttc agggtttggt
    11281 gaaagcgttg ataaggtcgt tgaagcaact aaaattgctc acgacttgcg tcctgacctt
    11341 gaaatcgatg gtgagttgca atttgatgca gcctttgttc ctgaaactgc agctctgaaa
    11401 gctcctggaa gtacggtagc tggtcaagca aatgtcttca tcttcccagg tatcgaggcc
    11461 ggaaatatcg gttacaagat ggctgaacgc ctgggtggct ttgcggctgt aggacctgtt
    11521 ttgcaaggtt taaacaagcc agttaatgat ctttctcgtg gatgtaatgc agatgatgtt
    11581 tacaagttga ccctcatcac agcagctcaa gcagttcatc aatagtgaaa actataaagc
    11641 gatatactat gctatactgt agttatgaaa ctatgtacga aaagcactgc cattaattcc
    11701 tgagaactaa attactgatt ggtgtcaaaa aggaaaactt ccaagcgatg atatcctgtc
    11761 tatacacgac ctatagaaat ctgtaatatg tatgtccgta aaacgataat ttcccttttt
    11821 gattttaaat gagtatgaaa agagaatttt ttcatgagaa aacgcataat attaagtgtc
    11881 ttgacacctg ctattatgcg ttttctggct ctttgtcaac tgtagtgggt tgaagaaaag
    11941 ctaagctcga gaaaggacaa attttgtcct ttcttttttg atattcagag cggtaaaaat
    12001 ccgttttttg aagttttcaa agttccgaaa accaaaggca ttgcgcttga taagtttgat
    12061 gagattattg gtcgcttcca atttggcgtt tgaatag
//
LOCUS       DAVAZT010000057        11679 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVAZT010000057 DAVAZT010000000
VERSION     DAVAZT010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11679
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.057"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..1017)
                     /locus_tag="VQT45_001725"
     CDS             complement(<1..1017)
                     /locus_tag="VQT45_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET2360012.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMKELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     KGEILEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESSEKFEAIKQNLVDEMWKVAQRELATGFYYGTPSENEQLFGARRKIPEYKFVAEVV
                     SYDDA"
     gene            1641..1823
                     /locus_tag="VQT45_001726"
     CDS             1641..1823
                     /locus_tag="VQT45_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET2360013.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            1833..2198
                     /locus_tag="VQT45_001727"
     CDS             1833..2198
                     /locus_tag="VQT45_001727"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET2360014.1"
                     /translation="MPNSENTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            2195..3385
                     /locus_tag="VQT45_001728"
     CDS             2195..3385
                     /locus_tag="VQT45_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET2360015.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RNGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(3900..4892)
                     /locus_tag="VQT45_001729"
     CDS             complement(3900..4892)
                     /locus_tag="VQT45_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2360016.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            5052..6806
                     /locus_tag="VQT45_001730"
     CDS             5052..6806
                     /locus_tag="VQT45_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2360017.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISAVLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIVTPILVLVLGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAEVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAIIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            6790..8511
                     /locus_tag="VQT45_001731"
     CDS             6790..8511
                     /locus_tag="VQT45_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2360018.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERIHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            8522..9151
                     /locus_tag="VQT45_001732"
     CDS             8522..9151
                     /locus_tag="VQT45_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET2360019.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALIALGAFLGGILGAYIGKALLKKHFSNGLYCVGYFTPCLILWCYLN"
     gene            9052..9609
                     /locus_tag="VQT45_001733"
     CDS             9052..9609
                     /locus_tag="VQT45_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET2360020.1"
                     /translation="MYRQGSIEKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIP
                     IVIRMFILPFMAASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKN
                     IKMAMRVRGINFKNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRV
                     KIQLIDFVYVLAVAGLIVGGLIWLK"
     gene            9597..10961
                     /locus_tag="VQT45_001734"
     CDS             9597..10961
                     /locus_tag="VQT45_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2360021.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGSGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDILEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDESSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKTSPFIFFDEPSSGIDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
BASE COUNT         4258 a         1670 c         1977 g         3774 t
ORIGIN      
        1 cgcatcatca taagaaacca cttcagcgac aaacttgtac tcaggaattt tacgacgagc
       61 accaaacaac tgctcatttt cagatggtgt accatagtaa aatcctgtag ccagttcacg
      121 ttgggcaacc ttccacatct cgtccactaa gttttgtttg atggcttcaa acttttcaga
      181 actttcaaga taggcatcca cagccgcctt gtagcagttg gttactgttg atacgtagtg
      241 aatagacttc atacgtcctt cgatttttag actgtccaca ccattttcaa tcatatctgg
      301 aatgtggtca atcatagaca tatcaacggc tgacattgaa aattcttcta gaatctcacc
      361 cttcaaactc ttacgttctt tcccaaatgg catatcgtaa aggtcgtatt tccaacggca
      421 tgactgagaa cacccaccac ggttggcatc acgcatactc atgtggtttg aaagagtaca
      481 acgtccagag tatgaaatac acatagctcc atggacaaag gcttcaattt caacatctgt
      541 acgtttgcgg atttcagcta attctttcat tgaaacctca cgtgctaaaa cgacacgagt
      601 caagcctagc tctttccaga actcaagggt ttcatagtta gtggcactgg cttgggtaga
      661 aaggtggatt tcaaggcctg gtgcttcagt cgctgcaatc ataatcaagg ctgggtcaga
      721 tacgataact gctgcaatcc cgatatcacg cagtttacga aaccactcac cagcaccagc
      781 ttcatttcct tcgtgcataa ccatattagc cgctacatag accttggcac catacttggc
      841 cgcaaactgc acgccttctt ccatctgttc gaaagtaaag tttcccgcac ggctacgaag
      901 accataggcc tgaccaccga taaagacagc atctgctcca tactgaacag ctacctttag
      961 cttctctaaa gtccctgcag gtgataaaac ctcaggacgt tttaatgttt ttgtcatgat
     1021 ttctcctatt tgcaatataa aagtttgaca tttttccttc tcattttata gtaaataaag
     1081 gataaaatca agcctagacg gattgttttg acaattctaa tcttttagac tttgcataat
     1141 aactattaaa cagtcgaaaa ttaccccagt tttaacaagt agtcaaaaag tctaaaaaag
     1201 taaaaaccag tatcccaaga tactgactcg taaaaatata taaattagtc cttagatgac
     1261 tactcccact ctgttgctcc tataatggaa aaggattgat acagtctaga atatcgcttt
     1321 tttatttatt attctgatat aaaactgtta gaattgattt tttgttttat acccaaatat
     1381 gaatagagac gtagctaata agttgaataa catatttgga aaaatgagaa atagcaatat
     1441 tactagaact tttagaaaca atcaatattt aaaaagaaaa aagctcaaag aatttattaa
     1501 accatgttat aatagatata gctataattt tatttataac aagaggatag aaatgaccga
     1561 attagaaaga aaaaatcgaa aaattagcta agaaatattc tgataactta aacatcaaag
     1621 ttcaagagag agttcgtgaa atggcaaatg ataataagag ccattatttg atatacagag
     1681 ttttaggtat ttcatttgaa gaaggagaaa atatcgattt gtatcaaaat aaaggtcgtt
     1741 ttttatacaa atatgctggt tcatttttag aagaagctgc agtactatcc tttaacgaaa
     1801 aatttggtac agaaaatact taaaaagtta acattcctaa ttctgaaaat acaaaaccta
     1861 agacttttga aattgattgt ttagtcggag aaaaacacgc atacgaaata aaatggtggg
     1921 atgcaactac agatggagac catataacta aagaacacac tagaataaaa gttattcata
     1981 acaaaggata tataccaatt cggttaatgt tctactatcc aaatagaact caagctataa
     2041 aaattcagca aactttagaa acattgtata acggtattgg agggaaatat tattatggag
     2101 attctgcctg ggaacattta agagcagtga ccggtattga tttacttagt attctaacag
     2161 atattgcaaa taaaaaaaca ggggtaaaat caaaatgaca gtattaaaag gagataactt
     2221 agaaatatta aaaactattg aatcctcaag tattgattta atctatatgg accctccttt
     2281 ctttacacag aaaacccaaa aattatctaa taacaaaaat attatgtatt cattcgaaga
     2341 tacgtggact tcgattgagg attacaaaga atttttgtct gtaagattag aagaatgcaa
     2401 aagagtgcta aaaaatagtg gcagtatttt cgttcattgt gataaaattg caaatcatca
     2461 tattagatta attttagata atatctttgg agcagatatg tttcaaagcg aaattatatg
     2521 gaactataaa cggtggtcta attcaaaaaa gggattattg aacaatcatc aaaacattta
     2581 cttttattca aagtcaaaag attttaaatt taatacaatt tttacagagt attcttctac
     2641 tacaaatatc gaccaaatac tagtagaacg aaaacgaaat ggaaactcta aaactatata
     2701 taaagttgat aataatggta actatattct agcaaaagag aaaaatggag ttcccctttc
     2761 agatgtttgg aatataccat ttcttaatcc aaaagctaaa gaaagagtag gttatcctac
     2821 acaaaaacct attctgttat tagaacaaat tataaagatt gctactgata aaaatgatat
     2881 agttttagac ccgttctgtg gaagtggaac tactttagta gcctccaaga ttttgaatag
     2941 aaattatatg gggattgatt tatctgagga agctatcaat ataactcagc aacgtctgga
     3001 aaatgttata aaaacaagtt caaatttatt gaataaagga atcgaagcat atagaaccaa
     3061 aactgaggaa gaggaaaaca ttcttaaatt attacaggca aaaattgttc aaagaaataa
     3121 aggaattgat ggttttttac ctaaacattt tcaaaaaaaa ccgataccta taaaaattca
     3181 aaaaaataat gaatgtctga atgagagtat ctctttatta cagaatgcta taaactccaa
     3241 aaaacttgat tttggagtag ttataaaaac tcattcagat aatttattat ttgattttga
     3301 tacgattcct gaaaatataa tagtagttga ccattttgaa cttacaatcg aaaaatggtt
     3361 aagtaaaagt caacagttac tatagtttgc aaattattta cagaaagaac aaaaaatgct
     3421 ctgaaacact gatttcaagg cattttttgt tagtttaaaa ttactcccat tcttcttttc
     3481 caaacgtaca atatatccaa aaccattcaa aatactagat tctatttttt ataatatcac
     3541 taaatccacc taattatagg acgttttcag atttttagtc ccgtcccagt cccagtaccg
     3601 gagaaatatt gttttaatat aatatctctt tttgtcttct aagctcttaa aagcaaaaga
     3661 acaagtaaag agtcaagaca aggataaaaa gtccatatta gggcaaataa aaagctttaa
     3721 gacagatgac aaatctaagt caaataagaa agaccatagc aaaggtgcag agagataaat
     3781 attggcggtc ttcggactgc ctttattttt ttatccattt ttcaaatcaa atttattcag
     3841 actatatatg cacatataca cttaaattca tataaaaaca tggcttgtaa aaaattactt
     3901 taatcacaat aatcgcattt aaaattgtga tgtttgcaag ctaaattacg gacttcactt
     3961 ggaagttttc ccttgtatct tttataatag atagaaaatt tgctggcaga tgaatatcca
     4021 acagattctg ctatctcttt tataggtagt tcagtgttta aaagaagagt ttcagctaca
     4081 ttcattcttt ttctttgagt gtactctgta atgctttgac aatatttttc cttaaataaa
     4141 ttttttaatt tagtaccact cattttagat attttttcaa gcgtgccttg atttacattc
     4201 gttgcaaaat gatcatctaa gaatcttgct acatcttcaa gtgctttatc atcatcaatt
     4261 tcaattttat atttttttct atttaagtat gtgtcaatta ctatacttat ccattcattt
     4321 gcctttgctt taaagaaaaa atcagcggca ggagcgtcca tcttacaatt taatatttcc
     4381 attgccactc tttctaaggc ctttgtaagt attatttgat tcggttgaag caaggttgaa
     4441 taaaaagatt ctggattaat gttaatagat gctaaatgtt tttctattag ctctttttta
     4501 aaaccaatgg aaacagcaag ataacaacaa ttctcgtgta ataaaaaaac aaaatcatct
     4561 tttatattat caaaatcaaa agtacataaa gagtttgcgg taatagtttg atacggatta
     4621 aacttttctc cgtttgcact gacaatgtaa cttgaataaa ttgaaacata gtctgacata
     4681 ctataagtgc tattttgaac tacttcctct ttgatataaa aatcatgtat atcgataatg
     4741 aagctgcctc cttcataaaa ccaatatagg ccttctgcat aagttgaatt ctcttttttc
     4801 caacaaaatg tatgacctgc acttgaatac ttctcattgt ttttacattc atctactttc
     4861 atataatctt ttacaaaatc ataatatgac ataacacact atccctttta gacaatattc
     4921 caattagcct tattaattca aaactattgt attagtaatt ataacagatg tataatagaa
     4981 aagcaatgat agatattatc aattaagcga atttatatct aaaagggata ttaaagaaag
     5041 gagatatgct tatgaagatt tacaaaaaac tatttgctta tgtccaagat aagaaatatc
     5101 ttggggtttt ggccataatt ttttctgcta tatctgctgt acttacagta tatggatatt
     5161 atttaatcta caaatttcta gataagttaa taattaattc aaacttatcc ggtgcagaga
     5221 gtatagcatt aaaatctgtt attacactaa caagtggagc gatattttat tttgtctcag
     5281 gaatgttttc acatatcttg ggatttaggc ttgaaacaaa tttaagaaaa aggggaatcg
     5341 atggtctgga aaaagcaagt tttaggttct ttgacttaaa tccatctggt caaataagaa
     5401 agatcataga tgataatgca gcacaaactc atcaggtggt agctcacatg attccagata
     5461 gctctcaggc aatagtcaca cctatacttg tccttgtact tggctttata gtaagtataa
     5521 gagttggcat aattttgctt gctcttacta taattggtgg cttaatttta ggggcaatga
     5581 tgggcgagca agaatttatg aagatatacc aagaatccct atctaaacta agtgctgaaa
     5641 ctgttgagta cgtgagagga atgcaagttg taaaaatatt taaagcaaat gtagagtctt
     5701 ttaaaagctt ttataaggcg ataaaagatt actcaaagta tgcttatgat tattccctat
     5761 cttgtaaaag gccttatgtt ttgtatcaat ggttattttt tggactgatt gcaattttaa
     5821 ttattcctat agtttatttt atgactagct tagctagcgc agaggtgatt ttacttgagc
     5881 ttatcatgat tttattttta tcaggagttc tctttgtttc attcatgaga atgatgtggt
     5941 actccatgta tatttctcaa ggaaattatg cagtagatac tttagaggcg ctttacgaag
     6001 atatgcaaaa agacaaatta gtgcatggta atgtcaataa ttttaaaaac tataatatag
     6061 aatttgagaa tgttagcttt gcttataatg ataaagctat cattgaaaat ttatccttta
     6121 atttagaaga aggaaagtcc tacgcacttg tcggttcatc tggatcaggc aaatcaacag
     6181 tagcaaaact tatatcaggt ttttacaatg ttaataaagg aagcataaag ataggcggga
     6241 tagcaataag tgaatattct gacgaagcct taattaaagc catttccttt gtttttcaag
     6301 attcaaaatt attcaagaag agcatttatg ataatgtagc tttagctaat aaagatgcga
     6361 cgaaagatga cgttatgaga gccttaaaat tagcaggatg cgatttaata ttagacaaat
     6421 tcccagaaag agaaaataca atcataggct caaaaggtgt ttatttatcc ggtggagaaa
     6481 aacaaagaat tgcaattgct agagcaattt taaaggattc caaaattatt attatggatg
     6541 aagcatcagc atctattgac ccagataacg agtttgaatt gcaaaaagct tttaaaaatc
     6601 ttatgaagga taaaacagtt atcatgattg cacacaggct atctacaatt aaagaccttg
     6661 atgaaattat tgtcatggat agtggaaaaa ttatagaaag agggtctgac aaagaattaa
     6721 tgtcaaaaga tacaaggtat aagagcctgc aagagatgtt taacagtgcg aatgaatgga
     6781 gggtttcaaa tgaaagagtt ttataaaaaa agatttgctc ttacagatgg aggagcaaga
     6841 aatttaagta aagcaacact ggcttcattt ttcgtttatt gtataaacat gcttcctgcc
     6901 atattactta tgatttttgc tcaggaagtt ttggaaaata tgggcaaaag caatggcttt
     6961 tatatagtat tctcagtttt gactttgata gcaatgtata ttttgctttc tatcgaatac
     7021 gataaattat ataacacaac ctatcaagaa agtgcagatt taagaataag gacagcggag
     7081 aatttatcaa aattacctct atcttacttt tctaaacatg acatttccga catttcacaa
     7141 acaatcatgg ctgatattga aggcatagag catgcaatga gccactcaat accaaaggtg
     7201 ggcggcatgg tactgttttt cccattaata tctgtaatga tgctagcggg caatgtcaag
     7261 atgggtttag ctgtaattat tccatctatt ttaagcttta tatttatacc tttatctaaa
     7321 aaatatcagg ttaatggaca gaatagatat tatgatgtct taagaaaaaa ctcagaaagc
     7381 tttcaagaaa atatcgaaat gcaaatggag attaaagcat ataatttatc gaaggatatt
     7441 aaagatgact tatataaaaa aatggaagat agtgagagaa tacacttaaa ggcggaagta
     7501 actacaattt taactttgtc tatatcttca atatttagct ttatatctct tgctgttgtg
     7561 atatttgtcg gcgtaaatct aattattaat aaagagataa attctctcta ccttatagga
     7621 tatttactag ctgctatgaa gataaaagac tctttagatg catctaaaga gggcttgatg
     7681 gaaatatttt atttatcgcc caaaatagaa agattaaaag aaattcaaaa tcaagattta
     7741 caagaaggcg atgactatag cttaaaaaaa tttgatattg atctaaaaga tgttgagttt
     7801 gcctacaata aagacgcaaa agttttaaat ggtgtaagtt ttaaagctaa gcagggagag
     7861 gtcactgctt tggtaggtgc aagtggctgc ggtaaaacaa ctatcttgaa acttatatca
     7921 agactttatg attatgacaa gggacaaatc ttaatcgatg gcaaagatat aaaagaaata
     7981 tcaacagaat ctctttttga taaggtctct atagttttcc aagatgtggt tctctttaat
     8041 caaagcgtta tggaaaatat tagaatcggt aagcaagatg caagtgacga agaggttaaa
     8101 agagcagcaa aacttgcaaa ttgcacagat tttatagaaa aaatggataa aggtttcgat
     8161 acagttattg gtgaaaacgg agctgagcta tcaggaggag aaagacaaag attatcaata
     8221 gccagagcct tcttaaaaga tgcgccgata ttgatcttag atgagataac agcaagcctt
     8281 gatgttaaca acgagaaaaa gattcaagag tctttaaata atttagttaa agataaaact
     8341 gttgtaatca tttcacatag aatgaaatcc atagaaaatg cagacaagat agtagttctt
     8401 caaaacggaa gagtagaaag cgaaggtaag catgaagagc ttttacaaaa atcaaaaatt
     8461 tacaaaaatt taatagaaaa gacaaaaatg gcagaagaat ttatttatta ggaggactac
     8521 aatggataat aaaaaattaa aagtaaaaga tttagtaagt atcggtgttt ttggcgtaat
     8581 ttattttgcc ttcatgtttg gagttggtat gatgggcttg attccaatat tgttcttaat
     8641 atacccgaca gtattagcca tagttgcagg aactgttgtt atgttattta tggctaaggt
     8701 tcaaaagcca tgggcactat ttatatttgg tatgatatca ccacttgtga tgtttgcagc
     8761 tggtcatacc tacgtagttg tggttttatc acttatagta atgataatag cagaattaat
     8821 tagaaagatt ggtaattata attcatttaa atacaatatg ctttcttatg caatcttcag
     8881 cacatggata tgtagctctt taatgcaaat gcttttagca aaagaaaaat atatggagtg
     8941 gtctttgatg acgatgggaa aagattatgt tgatgtatta gaaaagttaa taacttatcc
     9001 tcacatggct ttaatagcct taggtgcttt cttaggagga attcttggag catatatagg
     9061 caaggctcta ttgaaaaaac acttttcaaa tggattatat tgtgtgggat actttactcc
     9121 ttgcctaatt ttatggtgtt atctgaatta aaccctatag ttaagatgtt tttgagtata
     9181 cctattgtta ttagaatgtt tattttacca tttatggcag caagctttat gataaagacc
     9241 tcggatgtag gcgcaataat ttcatcgatg gataagctta agatttcaaa gaatgtatcc
     9301 atacctattg cggttatgtt tagattcttc ccatctttta aggaggagaa gaaaaacatc
     9361 aaaatggcta tgagagtaag agggataaat tttaaaaacc cagtcaaata tcttgaatat
     9421 gtttctgtgc cactactcat tatatcatct aatatatcag atgacattgc aaaagcggca
     9481 gaaacaaagg caatagaaaa tccaattgcc aagaccagat acattcgcgt aaagatacag
     9541 ctaattgatt ttgtttatgt tttagcggtt gctggactta ttgtgggagg cttaatatgg
     9601 ttgaaataaa aaatttaagt cttgattatg gtgaagagca tatattagat gatatatcac
     9661 tatccatagc cgagggagag tgcgtgctat ttacaggaaa aagtggaagt ggtaagtcat
     9721 ctttaataaa ttcaatcaat ggactagctg taaggtatga taacgcaaag acaaagggcg
     9781 aaataattat tgatggtaag aatataaaaa atttggaact ttatcaaatc tcaatgcttg
     9841 tttcaactgt ttttcaaaat cctaagacat atttttttaa tgtcaatacg acattagaat
     9901 tattatttta tttggaaaat atcggtcttg caagagaaga gatggacagg cgtttgaagg
     9961 atatacttga gatattcccg ataaaaaatc ttttgaacag aaatatattt aatctatccg
    10021 gcggtgaaaa acaaattctt tgcattgcag cttcttatat agcaggtaca aagattatag
    10081 ttatggatga gtcttcatcg aatttagata ttaaaagcat aagtgttttg gcaaagatgc
    10141 taaagatatt aaaagagaaa ggcataagca taattgttgc agagcataga atttattatt
    10201 tgatggacat agttgaccgt gtatttttaa tagataaagg aaagcttaaa aaaacttata
    10261 ctagaagtga atttttaaag ctagataaaa atgaattaaa tgctttaagt ttaagagata
    10321 aagaattaag taaattaaaa gttccttatt taaaagaagg tggagagtat cagataaaaa
    10381 atcttagcta caaatttact gatgatgagt gtttaagctt aaaagatatt tcgttcaagc
    10441 ttgggaaaat ttatggcata ataggatcca acggacgagg aaaatcaacg cttttaagat
    10501 gtttaatagg tcttgagaaa aaatcaaaag aagaaattta ttttaaggga gagaagctat
    10561 ctaaaaaaga aagactcaaa aactcttcac ttgttatgca agatgtaaat catcaattat
    10621 tcacagatga agtattcaac gagcttagat taggagtaaa gaattttgat gaagaaaagg
    10681 cgaaaatcat tttaaaagat ttaggcctgg acgaatttat tgaaaggcat ccgatgagtt
    10741 tatcaggagg gcaaaagcaa aggcttgcaa tagcatctgt tatgtgcaag acttctccat
    10801 ttatcttttt tgacgaacct tcaagtggta tagattattc caatatgata aaaatatctg
    10861 aactgattaa taagtataaa accatggata aaataatttt tattgtttcc catgatatag
    10921 aatttttaaa tgaagtggca gatgaaattt ttgaattgta aaatagagtc tgttaaacat
    10981 gtctatagaa ctggtaaatt gtctaaaaat ttaaaagata ctaacacata ttgatattta
    11041 ttagaaaatt aacttcagga tttttacagt atttataaac tttataatat gtatttatag
    11101 tattaataat ttccatatct ttagggaaat tatttattta cttaccataa ttaaagagat
    11161 gagagataaa tatcggcagt cttcggactg cctttatttt tttacttaat ttaatgcagt
    11221 aaatcatacg attgaaagga atctgcgtta tatgctataa ttaggtagtt aatctataca
    11281 tttagaaagg taaaatatag aattggagaa tgatatggga ttttcatata ataaattgta
    11341 accacccaat aacgaagtct attgaaaaat ctccagatta gtgaactcac ggatagttcc
    11401 taatctggag atttcttatt tgcacttttc ttgtacaact ttagtccatg gtaaataagc
    11461 ctctaaaacc tctttgttta cgagagtttc ctcgtttgga agacattcta gaagatagga
    11521 tagatatttc tcgctattta taatggattg aaataagata tgaacaaatc gattaggaaa
    11581 ggaaaattga tttatagaaa tattttagca gtcgatgcgt actgttatag attcaacgca
    11641 ctataattga tgacgtttag ctgtttccaa caaactcat
//
LOCUS       DAVAZT010000058        11394 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVAZT010000058 DAVAZT010000000
VERSION     DAVAZT010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11394)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11394)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11394
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.058"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(7..1221)
                     /locus_tag="VQT45_001735"
     CDS             complement(7..1221)
                     /locus_tag="VQT45_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2360022.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(1377..1670)
                     /locus_tag="VQT45_001736"
     CDS             complement(1377..1670)
                     /locus_tag="VQT45_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360023.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVKVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            1832..2284
                     /locus_tag="VQT45_001737"
     CDS             1832..2284
                     /locus_tag="VQT45_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HET2360024.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(2319..3707)
                     /locus_tag="VQT45_001738"
     CDS             complement(2319..3707)
                     /locus_tag="VQT45_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2360025.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            3773..4735
                     /locus_tag="VQT45_001739"
     CDS             3773..4735
                     /locus_tag="VQT45_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HET2360026.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(4732..4923)
                     /locus_tag="VQT45_001740"
     CDS             complement(4732..4923)
                     /locus_tag="VQT45_001740"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360027.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDETDEVSSKHVFEVVDRTDEVS
                     NHTYGRATLTWFAEIFEEY"
     gene            complement(4987..5997)
                     /gene="ccpA"
                     /locus_tag="VQT45_001741"
     CDS             complement(4987..5997)
                     /gene="ccpA"
                     /locus_tag="VQT45_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HET2360028.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKVGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(6422..7021)
                     /locus_tag="VQT45_001742"
     CDS             complement(6422..7021)
                     /locus_tag="VQT45_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2360029.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(7022..8119)
                     /locus_tag="VQT45_001743"
     CDS             complement(7022..8119)
                     /locus_tag="VQT45_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2360030.1"
                     /translation="MLERLKSIHYMFWASLIFMIFPILPVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLFWGIMLIYVAGNTAFVAVNYIWFFFFLSNLLSYHFSVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYLLGILTFVDLMTLGSVRIRLVEDLKEAQ
                     TKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQIQAYPQVEKELR
                     EIQQISKESMREVRTIVENLKSRTLTSELETVKKMLEIAGIEVEIANQLDTASLTQEL
                     ESTASMILLELVTNIIKHAKASKAYLKLERTDQELLLMVRDDGKGFETVTENELHTVR
                     ERVLPFSGEVSVISQKHPTEVQVRLPYKERK"
     gene            complement(8119..8856)
                     /locus_tag="VQT45_001744"
     CDS             complement(8119..8856)
                     /locus_tag="VQT45_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2360031.1"
                     /translation="MKRWIALNKIEFLLTKRQSVYYLLSVGMPTAFYLFFSGMYQDTP
                     GGPANFMRDYLISMTAFSMMSTAIFSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMMVDYLVSILVVFSVGHLVRGVDMSLGSWIGAAFLLIVGSIAFVALGLTLTLLPSS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAIGKCLPTYQLMELLKTFLNEGSINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(8858..9742)
                     /locus_tag="VQT45_001745"
     CDS             complement(8858..9742)
                     /locus_tag="VQT45_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2360032.1"
                     /translation="MNMIKVQGLHKNIKSKAILKDISFEVAEGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVYIQDLPVTSSKLDYTRSYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLNNQEIDQLLQFDQQQKEQFAEKLSGGQKRLLSFILTLIGRPKLVFLDEPTAAMD
                     TSTRQRFWEIVRDLKAQGVTILYSSHYIEEVEHTADRILVLNKGELIRDTTPLAMRSE
                     EIEKHFILPLAYKEVVEKSVLVENWVQKQDALQVVTCEADAFWELLVQAGCRIQEIEV
                     NNRSLLDTIFEETQKGDD"
     gene            complement(9729..9923)
                     /locus_tag="VQT45_001746"
     CDS             complement(9729..9923)
                     /locus_tag="VQT45_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360033.1"
                     /translation="MKKAILFLFIGLSLVVWLVEMFTGWFDQSFLHQVIRGAWGLGFM
                     ISVVFPMGMEWLKGEYYEHD"
     gene            complement(9920..10126)
                     /locus_tag="VQT45_001747"
     CDS             complement(9920..10126)
                     /locus_tag="VQT45_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360034.1"
                     /translation="MEEEEMRNKMIIAVSLVVAGVMTYLMFSGLDEGFYHFPWELFAS
                     FGIMSWLIREGLKLVRDVKKELEK"
     gene            complement(10611..10684)
                     /locus_tag="VQT45_001748"
     tRNA            complement(10611..10684)
                     /locus_tag="VQT45_001748"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10648..10650),aa:Pro,seq:tgg)
     gene            complement(10700..10773)
                     /locus_tag="VQT45_001749"
     tRNA            complement(10700..10773)
                     /locus_tag="VQT45_001749"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10737..10739),aa:Arg,seq:acg)
     gene            complement(10783..10868)
                     /locus_tag="VQT45_001750"
     tRNA            complement(10783..10868)
                     /locus_tag="VQT45_001750"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10832..10834),aa:Leu,seq:taa)
     gene            complement(10876..10947)
                     /locus_tag="VQT45_001751"
     tRNA            complement(10876..10947)
                     /locus_tag="VQT45_001751"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10913..10915),aa:Gly,seq:gcc)
     gene            complement(10970..11042)
                     /locus_tag="VQT45_001752"
     tRNA            complement(10970..11042)
                     /locus_tag="VQT45_001752"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11007..11009),aa:Thr,seq:tgt)
     gene            complement(11061..11142)
                     /locus_tag="VQT45_001753"
     tRNA            complement(11061..11142)
                     /locus_tag="VQT45_001753"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11106..11108),aa:Leu,seq:tag)
     gene            complement(11148..11220)
                     /locus_tag="VQT45_001754"
     tRNA            complement(11148..11220)
                     /locus_tag="VQT45_001754"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11185..11187),aa:Lys,seq:ttt)
     gene            complement(11245..11317)
                     /locus_tag="VQT45_001755"
     tRNA            complement(11245..11317)
                     /locus_tag="VQT45_001755"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11282..11284),aa:Asp,seq:gtc)
     gene            complement(11320..11392)
                     /locus_tag="VQT45_001756"
     tRNA            complement(11320..11392)
                     /locus_tag="VQT45_001756"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11357..11359),aa:Val,seq:tac)
BASE COUNT         3418 a         2641 c         2106 g         3229 t
ORIGIN      
        1 caagccctat ctacgatact gtttcaagaa acgagtcatc ttttcttgga tttgggctaa
       61 ctcatcaaca cgaggaaggt aaacgatacg gaagtggtct ggttcctgcc agttaaagcc
      121 tcgaccatga accaagagaa ccttttcctg cttcaagaaa tcaaggacaa actgctcatc
      181 atcatcgata cggtacatat tgcggtcgat ttttgggaag atatagagcc ccgccttggg
      241 tttaacggca gacaaacctg gaatatcttg aatggcatta tagatgaaat ttctttgctc
      301 gtagattcgt ccaccaggaa gaagcaattc atcgactgat tggtgacccc ccaaggaagt
      361 ttgtacgact tgttgggcca aaacgttaga gcaaaggcgc atattggaca gcatattgag
      421 cccttcgata tagcccttaa catgagtctt agggccagac aagaccatcc aacccacacg
      481 gaaacctgct atgcggtggg attttgacag accattcatg ctgacacaga agacatctgg
      541 tgccaagctc gccacaggcg tatgcacatg tccgtccatt accatgcggt catagatttc
      601 atccgcaaag ataatcaaat cgttttgacg ggcaatctca ataatctcca gcaagagttc
      661 cttaggataa agggctccag ttgggttatt tggattgata aggacaattg ccttggtatt
      721 ggaagtgatt tttgacttga tatcgtcaat atctgggtac cattccacag cttcatcaca
      781 gatatagtga acggcatttc ctccagctag gctgacagcc gccgtccata gaggatagtc
      841 tggcattggc actaagacct catccccatt gtccaaaagc ccctgcatgg acatgacaat
      901 caactcactg acaccatttc caaggtaaat atcatcaata tctacgtttg ggaatttctt
      961 cagctggcaa tactgcatga tggccttacg ggctgagaaa atccctttgg agtcagaata
     1021 gccttcacta tcacgcgcat tcataatcaa gtcatgaatg acctcgtctg gcgctgtaaa
     1081 gccaaattct gctggatttc ctgtattcag acgtaaaatc ttttctccat tcgctcgcat
     1141 ccgcatggct tcttccaata caggaccacg gatatcataa gcaacatgct ctaacttact
     1201 agacttgtta tattctttca tcttgtttcc tcaattcatc aggatagtaa cattatacca
     1261 ctagaaagag aatgcgacaa gtttactgaa atgtgttact agtttcgtat agaagaaaaa
     1321 ccttgctaaa ggcgaggtta agaacgtaga gatagcaggc attttgcaaa gacacatcac
     1381 ataccaaaag ataaacctag aaaaagcaag cctagaaagg agtcataaag aagattaaac
     1441 atgaggaaaa gcccccatat catcaagtaa tcccaacgcc cacttcgttt tgcaactaga
     1501 aataagatta gatggtagag tacatgaaag actaaaaatc caataaaact tggataaaga
     1561 agcggtacca gactctctaa ttgacagatc atgatcactt ttaccaagac tgaaactagg
     1621 ataattccat aatacaggaa atttgatttt tgaaaagagt ttttcatcat tctcccttcc
     1681 ttcacttctt tccttctatc ctttctttta ttttatcata tatttatata gattttaagc
     1741 cctaatattc ttttgaaaaa tacttttttt gctttacttc tatagtgaaa aggtttacaa
     1801 ttatagtaag aaaatttcag gaggtttcat tatggcacaa cgttaccaaa atatcatggt
     1861 cgcaatcgat ggttctaagg aagcggactt ggcttttgtc aagggagttc attctgctct
     1921 acgaaacgac gctaaactca ccatcgcaca tgtcattgac acacgcgctc tccaaagcgt
     1981 atccaccttt gatgctgaag tttacgaaga actccaagtc gacgctgaaa gtctgatgaa
     2041 agagtacgaa aaacgtgcta aagatgctgg ggtagcagat gttcatatcg tcattgaaat
     2101 gggaaatcca aagaccctgc tagcacgtac tattccagat gccgaggaag tggacctcat
     2161 cctcgttggc gcaactggtc tcaacgcctt tgaacgcctc ttggtcggct cttcatctga
     2221 atacatactc cgccatgcta aggtcgattt gctggttgtg agagaacaag aaaaaacctt
     2281 ataatcacaa agaaaaggag cccctagctc ctttttgttt acgatttatt tctctcttta
     2341 tggcgttcgt aagccttgag ctggcgctgc agttcctttt taatagcagg ttctggagca
     2401 tatttttctt cccaattatc tggttttaag attttatggg tcactggatc aaaatgagcc
     2461 ttgccatctg gaaaaatttt ccccatattg gcctgatgga caatatcaaa aatacgttct
     2521 gggtccaccc ccatcaagac aaaactgccg taggtgaagt aaagcgtgtc aatcaaggca
     2581 tccacttgcc ctatcaaatc ttgctgagca ggtgtcttct tggctacttt acctgctgcc
     2641 ttatcaaggg cctgatgaag ttgcgataca gcttgaccaa aatcttcttc agaaggactg
     2701 gctgctcgaa caaactccac caattcttct attttaaaac cagccctatg ggttgcaccc
     2761 tctaaatccc aagctcgagg ttcttcttgg gttcgttcat ccatcatgtg gtggaaggtc
     2821 ttgaccttat tgaaatgata gtcacggctg acaaagactt tttctgaaga caaaacacca
     2881 aaatgttcca aggccttgtg gatcccatct tgttgattgc tagtggtaat gtgcttggca
     2941 gcttccttga cactgctact accatttccc atagcgaccg acataccgac gccagccagc
     3001 atttcaaggt cattatctga gtcaccaaaa gccatgactt ggttgaggtc aaagccatat
     3061 tctttcccaa ctcggcgaat gccttctaat ttagaatttc cctgattgat gacatccgat
     3121 gcaaaaggat tgctacgtgt caatttcaag tcttcaaaat cagctgccgc cttctcagat
     3181 tcttctggtg tcatcagcat caaaacttgg tagataggct gattcatcag gtgaagcagg
     3241 tcctcttcct tttggggaac aaccttgctg accatgcgat taaaagactg actcaccgtc
     3301 cgagttaaaa cagagggaac gaagcgacta attcgttggg aaaaagaacc cagaccaaag
     3361 gacatgattt tagaacccaa catggcatcc ttggtcccta gggcaatctc cgtgccctct
     3421 tttttagcat agctaattag atggcgcaaa tgtaacttgg aaatagggct cgtgaacaag
     3481 actctgtctt tactaaagat atactggcca ttataggtta ccgcaaaatc cagatccaaa
     3541 tcgtccatca attccttaac aaaaaaaggt cctcgccctg tcgctacgcc aactagtacc
     3601 ccttgttctt tgacaatctt aatcgcgtcc ttagtggatt tcaaaacact cttgcgattg
     3661 ttgaccaagg ttccatcgat atcaaaaaaa acagctttga cttccatcct attccaatct
     3721 ccccttttgt gatacaatga ttataccaca tttcagaaag agtgagtaaa tcatgcctaa
     3781 gaaaatcctt gttttacata cgggtggaac tatttccatg caggccgatg cttctggcgc
     3841 tgttgtgacg agttcagata atcccatgaa ccatgtgtcc aacccacttg aaggaatcca
     3901 agtccacgcc ttggactttt ttaaccttcc aagtccccat atcaaaccca aacatatgct
     3961 ggtcctctac cagaaaatta aagaggaagc agataactac gatggagtgg taatcacaca
     4021 cggaaccgat actttagagg aaacagccta tttccttgat accatggaag ttccccatat
     4081 gcctatcgtt ctaacaggag ccatgcgtag ctccaatgag ctcggtagtg atggtgttta
     4141 taattaccta agtgctttac gagtggccag cgatgacagg gctgctgaca aaggagtttt
     4201 ggtcgttatg aacgatgaaa tccacgctgc caagtatgtc accaaaacac atacgactaa
     4261 tgtcagcacc ttccagactc caacacatgg ccccctcggt ctcatcatga aacaggaaat
     4321 cctctacttc aaaacagctg aacctcgtgt tcgctttgac cttgatcaca tacaaggttt
     4381 agtccctatc atctcggctt atgctggtat gacagatgag ctgattgata tgctggattt
     4441 agaacacttg gacggtttga ttatccaagc cttcggagct ggtaatattc ccaaagaaac
     4501 ggctcaaaaa ttagaaagcc ttctgcaaaa aggaatccca gtcgctctgg tatcacgatg
     4561 ctttaacggt attgccgagc ctgtttatgc ctaccagggt gggggcgtac agttgcaaaa
     4621 agcaggcgtt ttctttgtta aagaactcaa cgcccaaaaa gctcgcttga aactcctcat
     4681 cgccctcaat gccggactaa caggacaggc tttgaaagac tatatggaag gctaatactc
     4741 ttcgaaaatc tctgcaaacc acgtcagagt cgccctaccg tatgtatggt tactgacttc
     4801 gtcagttcta tctacaacct caaaaacatg ttttgagctg acttcgtcag tttcatctac
     4861 aacctcaaaa cagtgtgttg cgcagccttt aaccagccgc ctagtccgct ctatggtatt
     4921 cattaagtca acatctcttg tttaagagca caaaatcagg aaatcttctc gattccctga
     4981 ttttttctat ttacgttttc gtgttgagct acgttctgtc aaaccatgag gtaagagaac
     5041 ttcacgttct tccaactctt ccttatgcat aatcttggtc aacatacgca tactaatggc
     5101 accaaggtca taaagaggtt gggcaatcgt tgtcaagttt ggacgggtaa agcgtgagat
     5161 ttgtgaatca tcactagtaa taatttcaaa atcttctggc acagaaacac ccttatcagc
     5221 caaaccgttc aagactcctg ctgccaactc atcacctgtc acaactgctg cagttgcatt
     5281 tgatgaaatc aaacgctctg ctaaggcgta accatcatca tagctatatt tagattcaaa
     5341 taccaaaccc tcactataag tgattcctac ttttttcaag gtttccttgt agccaactaa
     5401 acgaacctta ccattgatgt catccactag cggaccgcta acgaaagcaa tacgctcatt
     5461 ttctttagca aggtagctca ctgcatcaat tgttgcttgc ttatagtcaa tattgacact
     5521 tggcaactgg tgctcaacat cgacagttcc tgcgagaaca atcggagtac gtgaacgcga
     5581 aaattctgag cgaattttat ctgtcaagtg ataacccata tagataatgc catctacctg
     5641 ctttgaaaag agggtattga caacagaaac ttctttctcg ttatcttcat cgctattagc
     5701 taggacaata ttgtacttgt acatttctgc aatatcatca atccccttag ccaaactcga
     5761 aaaataacca ttggtaatat ttggaatcac gacaccgaca gtggttgtct ttttacttgc
     5821 aagaccacgc gcaactgcat ttggacgata atccaaacga tcaattacct ctagcacttt
     5881 tttacgggta ttctctttta catttttatt gccattgacc acacggctga ccgtcgccat
     5941 ggaaacacct gcttcacgag cgacatcata aatggttact gtatcatctg cattcattcc
     6001 ttttcctgtc ctttctatct cacacattct tttacaagta gaggtactga ttgaagctct
     6061 atatctactt acaaaagtga agatgtgaaa atttcgtttt catatttcta cttattccat
     6121 tctatcacta attgtaaaca ctttcaagtg ttttttgaag attgattgaa aaaatttcat
     6181 agaaaaccta ggtttagctc cttgctacca ccttagacta aataaaaagg aggaaactaa
     6241 gcccttctaa agttatagta aaatgaaata agaacaggat aaatcgatca ggacagtcaa
     6301 atcgatttct aacaatgttt tagaagtaga ggtgtactat tctagtttca atctactata
     6361 ggtattgttc cattcactac cgtcaatttt agcacatagt cttcatgaaa atattatatc
     6421 atcataacca accagattct tttgcgatat tagctgcctc tgttcgatta ccagcatcca
     6481 gttttgaaag aatattggtg acatagtttc gaatagttcc gtttgagagg taaagctgat
     6541 ctgcgatttc ttggttggat aagccccggg cgattccctt taagacagca atctcttgtt
     6601 ctgtcaacgg attgggacgg gtcatcacca cttccatcaa ttcaggcgaa tactccttgc
     6661 gtccttcgag gacggtgtgc aaggtttgca tgaggtctgc aatgcttcgt tcctttaata
     6721 cataagcatc cactccagcc ttgaccgcac gttcaaaata cccagcacgc ttgaaggtcg
     6781 tcaccacaac cacctttgtt tcaagccttt ctgatcgtat ccactccaag acttcaagac
     6841 ctgtcttaac aggcatttct acgtcaagga tggcgatatc tacagactcc ttttctaata
     6901 gttggattgc ttcttgccca ttcttggctt gaaggacaga ctccacatct ggttgaagcg
     6961 tgagcaattg acacatagca tctcgcaaca tactttgatc ttctgcgact aatactttca
     7021 tctactttct ctccttataa ggtagtcgaa cttgcacttc cgttggatgt ttctgactga
     7081 ttacacttac ttctcctgaa aatggaagga cacgttctcg aactgtatgg agctcatttt
     7141 ctgttacagt ttcaaaacct ttcccgtcat ctctgaccat caggagcaat tcctgatctg
     7201 tgcgttctaa ttttaagtag gctttagacg ctttagcatg tttgatgatg ttggtcacta
     7261 attcaagcaa aatcatggaa gccgttgact ctaattcctg agttaagcta gctgtatcta
     7321 gttgattagc tatttccacc tcaattccag caatttctaa catctttttc acagtctcta
     7381 gttcggatgt caaagttcta gacttaagat tttccacaat ggttcgcact tcacgcattg
     7441 attctttgct aatctgctgt atttctctta attccttttc cacttgtgga taagcctgta
     7501 tttgaaataa ctgcaaggct agatcagttt taacactaag catagcaaag gtatgcccca
     7561 gactatcatg caaatcttga ccgatacgat tgcgctcatt ttctgctagc aatagattta
     7621 tctgggtatt ttgcttagtc tgagcttctt tcaaatcctc gacaaggcga attcgaaccg
     7681 agcccaaagt catcaaatca acaaaagtaa gaattccaag cagatagact agaaactcaa
     7741 cttcgattct ctgaaaaatc aaaagtcgcc ccacaacaag gacttgagca agaagaaaag
     7801 tccagacatg taaagacttt aaactacgta cgctgaaatg ataacttaag agattggaaa
     7861 ggaaaaagaa aaaccagata taattcacag caacaaaggc ggtattccca gctacataga
     7921 tcagcatgat cccccagaaa agccaagata ggcgctggct cttagttgtt aaaacaccca
     7981 aatatgccac tacaaataga atatcaatca ataaatgcca ggcagaaagc cacccagtca
     8041 ctacaggtag gatggggaaa atcataaaaa ttaaactggc ccaaaacata tagtgtatgc
     8101 ttttcagtct ttcaagcatt aagcattctc cttatgacct tgaaggtaaa tggtcaaacc
     8161 aaacaaaact gctgaaaaaa caagtagata aactgtggct gatagattga tgctaccctc
     8221 gtttaagaag gtcttgagca actccatcaa ctgataagtt ggtaggcact tcccgattgc
     8281 ttgcatccag tctggaaata aagagatggg catccagagt ccacctaaaa cagccaagcc
     8341 tagatagaga agattgccca cgacagacat cagctgacta gaaggcaaga gtgtcaaggt
     8401 caagccaagc gctacaaaag ctatacttcc tactatcagc aagaacgcag ccccaatcca
     8461 gcttcctaaa gacatatcca cacctctgac caagtgccca actgagaaaa caaccaggat
     8521 tgagaccaaa taatcaacca tcatacttgt tatctttgat agataatatt ctaccatatt
     8581 tacagggcta tgacgcaatg ttttctgcca gttgttcatc ttatcggtat gtaagacagc
     8641 tgggaatgaa aagatagcgg tcgacatcat ggaaaaggca gtcatggaga tgaggtagtc
     8701 gcgcataaaa ttagccggtc cacctggtgt gtcctggtac atgcctgaaa agaatagata
     8761 gaaggctgtc ggcatcccta cagataataa ataatagact gattgccgtt tggtcaatag
     8821 aaattctatc ttgtttagtg caatccatcg tttcatctta gtcatctccc ttctgtgttt
     8881 cttcaaagat tgtatccaac aaactacgat tattgacttc gatttcttgt atcctacatc
     8941 ctgcttgaac taacagttcc cagaaagcat ccgcttcgca tgtgactact tgtaaggcat
     9001 cttgtttttg tacccagttt tcaaccaaga ctgacttctc aacgacttcc ttgtaagcta
     9061 gcggaaggat aaaatgcttt tcaatctcct cactacgcat agctagaggc gtcgtgtcac
     9121 gaatcaactc tcccttattt aaaaccaaaa tccggtcagc tgtatgctct acctcttcaa
     9181 tataatgaga cgaatagaga atggtgactc cttgcgcttt taggtcccga acaatttccc
     9241 aaaaacgttg acgagttgaa gtatccatgg cagcagttgg ctcatctaaa aagacaagct
     9301 ttggtcgccc aattaaggtc aagataaaag ataaaagacg cttttgccca cctgacaatt
     9361 tttctgcgaa ttgctctttc tgttgctggt caaactgtaa tagttgatcg atttcctggt
     9421 tgttcaaggg atttggatag atacgttgaa agaaagcaat caactcttta acctttagtt
     9481 tttgaacaat tacattttct tgagggagat aggatctcgt atagtctaac ttagagctcg
     9541 ttaccggcaa atcttggata tatacttgcc cactggtgac caatttatct ccaagcaaac
     9601 agtccaagag tgtcgtctta ccagctccat ttggcccaat caaggcgacg cattcacctt
     9661 cagctacctc aaaggaaata tccttcaaaa tagccttact tttgatgttt ttatgtaagc
     9721 cttgtacctt aatcatgttc ataatattct cctttcaacc actccattcc catagggaaa
     9781 acgacggaaa tcataaatcc taatccccag gcgccgcgaa taacttggtg aagaaaggat
     9841 tgatcaaacc aacctgtaaa catttctacc aaccatacca ctagtgatag tccaataaaa
     9901 agaaagagaa tcgctttttt catttttcaa gctccttttt cacatctctt actaatttca
     9961 agccttctcg tatcaaccaa gacatgattc caaagcttgc aaacaactcc caaggaaaat
    10021 gatagaatcc ttcgtccaat cctgagaaca tgagataagt catgactcct gctactacta
    10081 aactcactgc gataatcatt ttatttctca tctcttcttc ctccatttca tactacaatt
    10141 atagtctttt gaaatcagag gagatagaag cttctgtcac taaaaaatat gacaaatgtc
    10201 ataaaaaatt ctgttcaaaa caagcaagat acactataca ataaaacaca attagataaa
    10261 tctaaggcaa cttcctcaaa agagatatca aaccccattc acactataat gtaaactaat
    10321 acttatttaa agtcaaaaga gcggaaattt ttatcgtaca aacatatata ttataggtaa
    10381 gacaaaaaac tcttcaatta ctttcttaaa aatttatagg agttataaaa tctattaaat
    10441 ttcaatgtgg atacctaaac tacagtattt attgaaaaga ctggagacaa aaagtatacg
    10501 ctgccaaaat gaattgctga aaatcaaaaa agagagaagc aaactgattc tctcttaatg
    10561 tatataatat ctagttataa aaatacacac tcacatatct ctgtaatgaa tcgggaagac
    10621 aggattcgaa cctgcgacac cttggtccca aaccaagtac tctaccaagc tgagctactt
    10681 cccgagttaa atagaaaaat gcaccctaga ggagtcgaac ctctaaccgc ctgattcgta
    10741 gtcaggtact ctatccagtt gagctaaggg tgctccatat tatgccgagg accggaatcg
    10801 aaccggtacg atcgttacca atcgcaggat tttaagtcct gtgcgtctgc cagttccgcc
    10861 accccggcct ctctaagcga acgacgggat tcgaacccgc gacccccacc ttggcaaggt
    10921 ggtgttctac cactgaacta cgttcgcact gttttcttct atctaaaaat gccggctaca
    10981 tgacttgaac acgcgaccct ctgattacaa atcagatgct ctaccaactg agctaagccg
    11041 gctcatttgt tatatcttaa tgcgggttaa gggacttgaa cccccacgcc gttaagcgcc
    11101 agatcctaaa tctggtgcgt ctgccaattc cgccaaaccc gcatatatga cccgtactgg
    11161 gctcgaacca gtgacccatt gattaaaagt caattgctct accaactgag ctaacgagtc
    11221 taaaataact tgcgttacct taaacggtcc cgacgggaat cgaacccgcg atcttcgccg
    11281 tgacagggcg acgtgataac cgctacacta cgggaccttt gggagttaac gggatcgaac
    11341 cgctgaccct ctgcttgtaa ggcagatgct ctcccagctg agctaaactc ccta
//
LOCUS       DAVAZT010000059        11272 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVAZT010000059 DAVAZT010000000
VERSION     DAVAZT010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11272
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.059"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..947)
                     /locus_tag="VQT45_001757"
     CDS             complement(<1..947)
                     /locus_tag="VQT45_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2360035.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQVIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFILVTFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTI"
     gene            complement(1027..1890)
                     /locus_tag="VQT45_001758"
     CDS             complement(1027..1890)
                     /locus_tag="VQT45_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET2360036.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTSLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(1893..3794)
                     /locus_tag="VQT45_001759"
     CDS             complement(1893..3794)
                     /locus_tag="VQT45_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2360037.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENAAV
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINCVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
     gene            complement(4222..4497)
                     /locus_tag="VQT45_001760"
     CDS             complement(4222..4497)
                     /locus_tag="VQT45_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HET2360038.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(4603..5442)
                     /locus_tag="VQT45_001761"
     CDS             complement(4603..5442)
                     /locus_tag="VQT45_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET2360039.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVIVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRIGRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            5584..6432
                     /locus_tag="VQT45_001762"
     CDS             5584..6432
                     /locus_tag="VQT45_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET2360040.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(6525..7442)
                     /locus_tag="VQT45_001763"
     CDS             complement(6525..7442)
                     /locus_tag="VQT45_001763"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HET2360041.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            7879..8084
                     /locus_tag="VQT45_001764"
                     /pseudo
     CDS             7879..8084
                     /locus_tag="VQT45_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(8395..8688)
                     /gene="rpmA"
                     /locus_tag="VQT45_001765"
     CDS             complement(8395..8688)
                     /gene="rpmA"
                     /locus_tag="VQT45_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HET2360042.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(8705..9049)
                     /locus_tag="VQT45_001766"
     CDS             complement(8705..9049)
                     /locus_tag="VQT45_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HET2360043.1"
                     /translation="MIQAVFERAEDGELRGAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(9065..9379)
                     /gene="rplU"
                     /locus_tag="VQT45_001767"
     CDS             complement(9065..9379)
                     /gene="rplU"
                     /locus_tag="VQT45_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HET2360044.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYIEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(9415..9502)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(9597..10196)
                     /locus_tag="VQT45_001768"
     CDS             complement(9597..10196)
                     /locus_tag="VQT45_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HET2360045.1"
                     /translation="MTFCAGYVDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDVR
                     DKLLTLITFIMGVFLLTIYKEKLRIVKKPILSLIPLAILSIIIGFVPQTVDNIYLVQP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLL
                     SSFVLGDVFSAYLTIFYHEKTILGVPIMMSIFYLSMLFA"
     gene            10666..10965
                     /locus_tag="VQT45_001769"
     CDS             10666..10965
                     /locus_tag="VQT45_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HET2360046.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT         3573 a         2333 c         1870 g         3496 t
ORIGIN      
        1 aaaatcgtca taaacaattc acaaactaaa tttccagaaa aggaaagaaa agttggaagt
       61 ggtaatccca tcataaaaac tccgacacct gtcaaagcca gtaaaatcaa aagattataa
      121 atattagctt taattttact agctagaaga gccccaatga tggaaccaat agcccccata
      181 gttaaaatac ttgcataggc tccttctgac ccgtaaagct gattcgaaaa gggaagtaga
      241 aattcaaaag ctgcaaaaaa gaaattaacg ctggaagcta ccagcaaaag gaagaaaatt
      301 tcttgctgat gccagatata gtgtaaccca tccttgatat ctacaaaaat atctctccca
      361 gtaaaagcct ttttctcttg aacttttgct tcctcttttg gaaggaaagt cactagaata
      421 aaagcaatga aaaaagtcag cgagtctagc agtagcgtca tatggagact tgcaaactgt
      481 aaaacaagga aggaaagaac aggagagcta acacctacaa cctgcaaaac cagctctaag
      541 cgagaattat agatcacaat ctcatctttc tccaccactt cagttatgat agctttattg
      601 gctgtgcgag aaaaggcaaa agcaataacc tgcacaatgt tagcaacaat caaagcgcca
      661 atcatccagc tatcattcct tatgaaagaa atagccagac aaagaatccc acaaacaaga
      721 tctgccgtca ttaaaatctt acgacgagaa aaacggtctg aaataactcc gccaaaggga
      781 ttgacgagaa tagatgtgac gagctcagaa atctgataca ttcctaaaac tgtctgtcct
      841 atagtcccca tagaagccaa ccagacacta tttccataat catagagcat atttcccatt
      901 ttattgatag ccccacggct aatcaactgc actgcatagc gattcatatt aaagctcctc
      961 tcaaattttg aaactattgt atcaaaaccg aaaggagctt tttatttttt cccttatttg
     1021 ggaaaattaa cttttgacaa atttttcgta gtgttcctga taataggcta cttgctctgg
     1081 aagacctaac acatcaaaaa tatgcatggc ctcttgcatc tgcttacagc cttctttaca
     1141 ctgtcctttt tgatataagg caaaaccttt taaataatgg aaaacattac gctcataaag
     1201 cttaatacct ttgtcaataa tcttctctgt ataagcctca aaatagttgg cattataaaa
     1261 agaagaatgc tctaaacaat gctggtaaca attgagggcc aaaatcaaca ctaatctctt
     1321 atggcgacta atctcttggt aaaattcctc cctctccata acttctctac caatccgagt
     1381 gacatagtct acatcgtaga aactatagag gttaccgaaa agaatcaact catacatggt
     1441 ccattcttct gttttgaaga gataatctgc taccttatcc aaatcatcct gcttcatatc
     1501 ataactcgca tctctttgac aaatcagacc ttgtagcaaa atccagttca gctcaaaata
     1561 aagggaagtc gtcgaactct tagacttttc aagttgttct ctttgaagct tttgaaaacc
     1621 tgcaatatcg tttgaatagt aaagtgggat aatctgtgcc atcatagaca catgttcatg
     1681 attatgaaaa ttccttgcct tatccatgaa attttcgatt gttacatgaa tgttatccaa
     1741 aatctcaaag aaacgggaga ctgccaggtc agactcccca agctcaaagc gagataactg
     1801 agaggtagag caggattcgc ctgctgcttc ctttaaagaa taatttccac ttgttcgaaa
     1861 ttcacgaaat acttttccaa gatgttccat ctttacacct gatctgataa ttcttcccac
     1921 tcaagcatag cttcttcctg acgatggctg attttatcca gctcagcctg taattccatg
     1981 agtttgtcgg catcgtttgt ttccaacatt tgttcagaaa tggcttggct ttgactttct
     2041 agctcttcaa tttcagcttc tagactttcg atttgtcgca tgagtttgcg aacttctttt
     2101 tgactttctt tctgggcctg atagtcattg actggacttg cttcctttgc ttgattgcta
     2161 gttgaagctt cctcagtctg actcatttct gctgttgctt tcttctcaac atagtagtcg
     2221 taatctccaa ggtagagagt tgaaccattc tcagacaatt ccaaaacatg agttgccaca
     2281 caattgataa agtaacgatc atgactgaca aaaagcaagg taccatcaaa gtcaatcaag
     2341 gcattttcta gcacttcctt actatcaata tccaagtggt tggtcggctc atccagaatc
     2401 aaaaagttat tgttttccat agacaattta gctaaaagca aacgagcttt ttcgccacca
     2461 gatagcatgc cgactgattt tttaacatca tctcctgaga aaaggaaggc tccaagacgg
     2521 ttgcggattt caacttctgg tgtcaatttg aaatcattcc agagttcatc cagcaccgta
     2581 ttacttggtg tcagcttgct ttgggtttgg tcatagtaac caacctcaac attagcgcca
     2641 aagcgctttt ctcccttgat aaacggaatt tgatccacga ttgatttgat aaaggttgat
     2701 tttccgatac cattgggacc aacgatagca acagcattca tcttacgaag gtctaggtta
     2761 atcggttgtg acaggacttc cccatcatag ccaacagccg cattttcaac agtcaaaaca
     2821 acattgcccg acgttttttc agactggaag gtcatgttgg ctgctttctt gccagcttcc
     2881 ggcttgtcca aacgctccat tttttctagt tgtttacggc gagattgagc acgtttggtc
     2941 gttgaagcac gaactagatt gcgattgaca aagtcttcca gagcagcgat ttccttctgt
     3001 tgcttttcat agttttttgc ctcagtagct agcttttgct ccttcaactc gacaaaacga
     3061 gagtaattcc ccacatagcg atccaaggaa tgcttggtca aatctagcgt aattgtcgca
     3121 accttgtcca agaaataacg gtcgtggctg acgataatga gggcaccgct atagtttacc
     3181 aagtaattct ctagccagga gatggtttca atatccaagt ggttagttgg ctcgtccaag
     3241 accaagagat tgggcttttc aaggagcatt ttagctagag ccaaacgagt attttgacca
     3301 cctgaaagtt cagctatttt catctgccac atagactcgt caaacttgaa tccattcaaa
     3361 atcgctcgaa tatcagcttc ataggtaaag ccacctgctt ggcgaaaatt ctcagataag
     3421 cggtcataat ctgacatcag tttatccaaa tcctcaccag acttttcacc catctccagc
     3481 tccatctgac gcagttgtct ctccgtccga cgcaaatcat taaagacatg aagcatttca
     3541 tcgtagatgg tattttcaga ctcaaaacgg ctatcttggg ctaggtaaga cagagaaata
     3601 tcttttttct tattgatttc tccgctagtt ggctcctctt ctccaactaa aatcttcaaa
     3661 agagtagact tacctgcacc atttttccca acaagagcaa tccgatctcg ttcatcaacc
     3721 tgcaggttga tattatcgaa aagaacctct cctgcaaaag aacgttcaat tttattagct
     3781 tgtaaaataa tcataagagt agtatagcat gtttccctaa ggcattcaag ataatcgtaa
     3841 gtcttttagt acaactttta taacataaaa taaactaaat tatgtatatt ttatattaga
     3901 ttccttcact atcttgttgg attttctaac cagctaatct tgtttcaaat agttatcgca
     3961 caagcctatt atttaattct tttcattatt tacgtacgcg tatagcagat tgaaataaga
     4021 tgagaacaaa tcgattggga aagtaaaatt aatttctata aatgttttag caattgtttc
     4081 gtactatttt agattcagtc tactatgtac aatattttcg gaacattcaa ctttttaact
     4141 ctatttatta ctagatttca taattaaaaa gcctactgac caagctagaa agcttgatac
     4201 aataggcttt ttaaagactg attatttaac agcgtcttta agagctttac cagctttgaa
     4261 tgctggtact ttagaagctg caattgtcat ttctttacca gtttgtgggt tgcgaccttt
     4321 acgttctgca cgctcacgaa cttcaaagtt accaaaaccg atcaattgaa ctttttcacc
     4381 agctgcaaga tagtcagcta ctgctgcaaa tacagcttca actgctgctg ctgagtcttt
     4441 cttagtcaat tctgtagctt ctgctacttt agcgatcaaa tcttgtttgt ttgccatgtt
     4501 aatgattcct ccagataatt tctaattaac aaatataatc atatcctaaa atccctttta
     4561 ggtcaagtta aaaacgctat ttcttccaat tttatttatt ttttaggagt ggtaacgtat
     4621 caaaatagcc caagcgttct cacccgtgtg agtttgaata atggaacccg tttccaaaac
     4681 agaaattggc ttttcaacat aagcttgtaa gctttctttc atctcttttg cccaatcatc
     4741 actaccagaa tatgaaattc caatctctgc tacagcacgt tcagaaagcg atgttatcaa
     4801 ctcatctaac cattttttaa atgttttagt tccacgacct ttaaccattg gctgcaattc
     4861 atggtctttc atttgcatga caacacggat attgagaagg gagctcaaca agccagttac
     4921 acggccaatt cgtccacctt tgacaagatt ttccaaagtt gaaacaccaa tataaagctc
     4981 tgtatggttt ttaacctctt ctacatgaga taaaattgcc tccatatctt taccttcttg
     5041 agctaacttc gcagcctcaa caacttggaa tttcagggct tggtcagtga aggaactatc
     5101 aacaacaatc acatctgcag tagataggct agcaccttgg cgtgctgctt ctaccgtacc
     5161 cgaaagagca tgggacatat gaatagcaag aatctggcca ccatctttgc ataggtcttc
     5221 aaaaatctca gcaaagacac ctacaggtgg ctgacttgtt ttcggaagat tcttactttc
     5281 ttgcatcaac tgaagaaatt taccttcttc tttcaaatcc gcatcagaat aaacaacatt
     5341 atcaatcatt acagataatg gaacaattgt aatatctaat tgctttacta gttcaggttc
     5401 aatagtaaca gatgaatcgg ttacaatctt aatttttgtc atagtatcaa tctttctatt
     5461 ttaggattca gattggtttc cttacttcta attatatcaa aaaaaagatt aaaaatccta
     5521 atggagtcaa tcaaattttc cgtaaaattt gatataatca acttataaga aaagaggtgt
     5581 cctatgatta aaaaaattta ccccattttt accattttac taggtgctgc tatttatgct
     5641 tttggactga cttattttgt agttccccat catctctttg aaggaggggc gacaggtatt
     5701 accctcatca cattttatct ttttaaaatc cctgtttccc tcatgaacct gctgattaat
     5761 attccccttt tcatcctagc ttggaagatc tttggagcca aatccctcta ttctagttta
     5821 ctaggaacct tagctttgtc cggctggtta gctttttttg agcatattcc ccttcatatt
     5881 gatcttcaag gtgatttact aataacagcc cttatagcgg gaatcctatt gggaattggc
     5941 cttggaatta tttttaatgc tggaggtaca actggcggaa ctgatattct agctcgtatt
     6001 ctcaacaaat acactcatat atccatagga aaactgctct ttatcttaga tttttgtatt
     6061 ctcatgttga ttctcctaat cttcaaggat ttgagattgg tttcctacac gcttttgttt
     6121 gattttattg tttctcgtgt tattgatttg attggtgaag gaggatatgc cggcaaaggc
     6181 tttatgatta tcacaaaacg tcctgaccaa cttgctaagg cgattaatga tgacctcgga
     6241 agaggtgtta cttttatttc tggtcaaggc tactatagta aagaaaattt gaaaatcatc
     6301 tactgtattg tcggaagaaa tgaaattgtg aaaacgaagg aaatgattca tcgaatcgat
     6361 cctcaagcct ttataactat tacagaagcc catgaaatcc taggagaagg cttcaccttt
     6421 gaaaaagaat aaaaagaggt aatgtcgtga cctcaaaagt tagactaaat catctatctt
     6481 ttgggttaca gacaacctct tttttgtttt atttactcaa gctcttaaga ccaattccga
     6541 gttacttctt catcagcctt taactgatcc actaattggt caactgagtc aaatttggtc
     6601 atatcacgaa tgcgatcaag ccaataaacc atgacggttt ccccataaat atcttgatta
     6661 aaatcaaaaa tattgacttc aaaacgtgct tcttctccat caaaggtcac atttttcccg
     6721 acactagcca tagcacgata cttctgtctt tgaatctcaa catcaacgac ataaacgcca
     6781 tctgctggca tataagtacg gtctaaaagc actaaattcg ctgtcggata accaattgta
     6841 cgaccacgag cattaccatg aaccaccata cctcttgatg gaagcggtgc ccccaaaagt
     6901 tttcctgctt ctttcacatt tccatctaaa atagcttgac ggatacgagt tgaactaatc
     6961 tttcctttct catcttctac aggtggaaca atgataactt ctccatcaaa gtaatccttt
     7021 aaatcttctg ctgttttttt gtcagaacca aatgtataat caaaacctgc aacaataatt
     7081 ttggcattca tagccttgat ataagttgca aagaattctt gtgcagtgag actagcgaat
     7141 tgactactaa aatcaaggag atataattct tctacacctt cgcgctttaa ttttctttca
     7201 cgttcagcag ggttcaaaat atgcaaaaac aaatccggat gataaggctc taaagcgatc
     7261 tttggagatt cattaaaggt cataacgacg ataggtaata aatcctttct cgcagccttg
     7321 ttggcaacac gaaataattc ttgatgcccc ttatgtatgc catcaaaata gccgagaaca
     7381 acgactgaat cagatggtgt gccaatatct ttttggtttt ttataggaat agtaataatc
     7441 ataaaataat tatatcatag cgatagctat ttctggaaca gaaaatctga aatgttgttt
     7501 ttttcacatg aagtgtacct gttttcaaaa agcactttat tctatcgttg cttaactatg
     7561 aactttgcaa tattcttctc aaaaacttgt aggacatctt caaaattttg caaggagtga
     7621 ttagacttgt tcggtaacca taaagtgtca tactatgtta tgtatgaaaa agcaatgcaa
     7681 ctaactcctg agaactttaa attactaatt ggtgccgaaa aggtagaatt tagaatcgag
     7741 gtacacctat ggctgtaaaa tttacaaaat gagacaactt gggcaagatg tttgaagaat
     7801 ttcctaaact ccctgatttg aagcaagtca ctttccctga tgacaaagaa aaaagccaaa
     7861 acagcaaaga aaaactagat gactgctttc caacaactcc catctagtgt gcttcagact
     7921 gggctatttt tctctccatc tgttagcttg gattctcaga ccgtttcagc taaagaatat
     7981 cttttccctt atcagaagga acggctcaaa ccattcagac aagtgaaggg acgacaagcc
     8041 aatatttgaa accagatagc agttcttata gtcaattgaa ataaaatctg aagaaatcga
     8101 gtaggaaact catatcaatt tttaacagtg ttctattcca gattcatact caatgaaaat
     8161 taaagtgcaa actaggaagt tagccgcagg ctgtacttga gtacggcaag gtgaaactga
     8221 cgtggtttga atttgatttt cgaagagtat caatccacta tacatattaa aaagtatgga
     8281 tatcaaaaca aaaaaacagg ctctccgaaa actcggaaag ccttatttta agctgtttct
     8341 agcttcctca cctttacatt tcaaggttcg ggataaaagg ttcaatggac ctttttattt
     8401 agcgattggg taaacagaaa cttgtttttt atcgcgtcct ttacgttcaa agcgtactac
     8461 gccttcaact ttagcgaaca aagtatcgtc tccaccacga ccaacgttta cacctggata
     8521 gatgtgtgta ccacgttgac ggtaaaggat tgatccacct gttacagttt gtccgtcagc
     8581 tgctttagct ccaagacgtt ttgcttgtga atcacgtccg tttgatgtag aacctccacc
     8641 ttttttgtgg gcgaaaagtt gcaagttgtt aagagtcatt tttaacataa tgttttcctc
     8701 cgtgttagtt ttctgtgata actctggttt ggacgaactc agaatagttc tccgataagt
     8761 ttgccatacc taagaaaaat gattcaaaga ataactgggt catttctctc tggtgtgaag
     8821 gaagatcttt tggtatttca accatcagat agccaccttc atcttcgttt aattctagga
     8881 ttggttcata gcctgcaaat ttctcaatag aattgataaa gttaatggca agcgtagaaa
     8941 ccgatgcaca cacgacatct aagccgtatt cgccactctc ggcgtgtcca gtaatttccg
     9001 cacccctcag ctcgccatct tcggctctct caaagactgc ttgtatcatg tgttctcctt
     9061 aaaattaagc gttaattgcg ttgatgacaa cttttgtata tggttgacgg tgaccttgtt
     9121 tacggtggct acctttttta ggtttgtact tgtaagtaac aactttcttt tgttttcctt
     9181 gtttttcaac agttccaact acagtagctc cagcaacaag tggagttccg acaacagtgt
     9241 tttcaccacc aacaagaaca acttcgttaa aagtaacttc ttgaccagct tcaacgttca
     9301 atttttcaat gtaaactgct tgaccaactt caactttaac ttgttttccg ccagttttga
     9361 taattgcgta tgtgctcatt atgcacctcc tatgattttt atgggtttcc ccgatttttt
     9421 gtgaagactc gcctagcatc gtgggacaaa ccacttaaac ttgaataatc aagcaacgat
     9481 gttcgtgcgg ttgcacagga tcgtgcatag tcaactcttc aagtatagca tatctcctat
     9541 tttcttacaa gtaataacac ctaaaatcaa gctttttctt ttactttttt ctgccactag
     9601 gcaaaaagca tactgagata aaaaatgctc atcataatag gaacaccaag aatggtcttt
     9661 tcatgataga aaatcgtcaa ataggctgaa aagacatcgc caaggacaaa actactaagc
     9721 aggctaacaa atatgaaccc ttcacgcaaa aaaggagtgt gcttagttcg gaaataatct
     9781 ccaaaagcta gcattgttcg tttgatattc cctgtcataa aggcattatt gtaggcaata
     9841 cccgaaacct caccaaaagc agttgtcacc agtcccatac agaaggccaa gggctgcact
     9901 agatagatat tatctacagt ttgtggcaca aaaccaataa ttattgatag gattgctaaa
     9961 ggaatcaagg acagaatagg ttttttcaca attctcaatt tttccttata aatcgttaat
    10021 aaaaagactc ccattataaa cgttattaag gttaaaagct tatccctaac atccgaaaca
    10081 ttattttgta ttagctctac cgaaagaaag acaacatttc cagcttgtcc agctacaagg
    10141 gtattccctc gaacaataaa agtgtaagca tccacatatc cagcacaaaa tgtcaaaaaa
    10201 gtgctaacct tttagactga cgtgatattt ttcttatagg taataacctc attttccctc
    10261 ccattgtatt ttctcttaga aatattgtac catttctttc taaaaaatcg tagactacca
    10321 tttagatttt actattagca taaaaataat aatagacaac tatttatcca aaaatagata
    10381 gaggtaacat gtttgcaaac aaagcatacg aacctttagt aaaatcattt ccatgaaact
    10441 agaatagagc ccctcttagc aaaaatcatt attttaattt atttctaatc actccttgac
    10501 ataaataact ctcaccaata aaagactatg tcttaaaaaa atggtataat aaaatcaata
    10561 cctgggcttg atggctatgc tactaataac aattaggaga gaaaatcagg cacttgttaa
    10621 caacaaggat tatccccttg agatgaaagg aactttagaa atcttatgat gaacatgcaa
    10681 aacatgatgc gtcaagcaca aaaacttcaa aaacaaatgg aacaaagcca agctgaactt
    10741 gctgctatgc aatttgttgg caaatctgct caagatcttg tccaagcgac cttaactggc
    10801 gataagaaag ttgtcagcat tgatttcaat ccagctgtcg ttgacccaga ggaccttgag
    10861 actctttctg atatgaccgt tcaagccatc aactctgctc ttgaacaaat cgatgaaact
    10921 actaagaaaa aactgggtgc tttcgctggg aaattgccat tctaaaaaca aggagctaga
    10981 acaatacttg tcgataacaa aggctaagaa aggtgcaaaa attataaaaa acgcatagta
    11041 tcaagcaacc taaaactttg ggctctataa tatttgtagt gggtaaatcc actatagata
    11101 ttatggagcc tattttattg tagaaaaaaa tcccataaga tctataatga aaagcgacca
    11161 aacaactcat tagaaagatt catatgggac aattacattt tatcacaaaa ttactagaca
    11221 ttaaagaccc taatatccag attttagaca tcatcaataa ggatacacac aa
//
LOCUS       DAVAZT010000060        11268 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVAZT010000060 DAVAZT010000000
VERSION     DAVAZT010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11268)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11268)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11268
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.060"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..77
                     /locus_tag="VQT45_001770"
     CDS             <1..77
                     /locus_tag="VQT45_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET2360047.1"
                     /translation="MPQSPWVERIVQVLDLDYEDLFRR"
     gene            80..667
                     /locus_tag="VQT45_001771"
     CDS             80..667
                     /locus_tag="VQT45_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2360048.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCSDELTILQILYGASLIS
                     FLWMYGQRKQVIKVNMKTRIQWLGIGFVSLLIISLCFSLIHAQESTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTIIAWCLYV
                     SLGMFLGLVRYKLDLWGSMGLHLVWNLLVYSLLLF"
     gene            1066..1875
                     /locus_tag="VQT45_001772"
     CDS             1066..1875
                     /locus_tag="VQT45_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET2360049.1"
                     /translation="MLLQKELIPMIEANLPNMAYAEKDIAKFFLKQQPLNNYSCKALC
                     ECLNVSKATLTRFAKKCGFKGFRQFIFKYQEMIREKEKLALYTEATEKVLSDYEEMLR
                     KTYTVLDEVQLERIAEMIETAERVYLYGKVSSVLALQEMKMRFMRLGVIGEVLSDEDM
                     ILWNSLLLNENCLVIGASVSGQTDIVLEGLQKAADKGAKTVLMTTRKFDEEDCFFDEL
                     LLLASTNHLSYGNRISPQFPILLITDCLFSHYLESPERQYYYNQTIIHKEE"
     gene            1880..2581
                     /locus_tag="VQT45_001773"
     CDS             1880..2581
                     /locus_tag="VQT45_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET2360050.1"
                     /translation="MSQIWTKEKFISQVHGGVIVSCQALPGEPLYNEEFSLMPFMAKA
                     ALEAGAVGIRANSVRDIKAIQKVVDLPIIGIIKRDYPPQEPYITATMKEVDELVECGT
                     TVIAFDATLRPRYDGLVINEFIKKIKEKYPNQLLMADVSNFDEGLYAFKSGVDFVGTT
                     LSGYTSTSVQSDEPDFELMKKLADFNIPVIAEGKIHYPEQLKKAYSLGVTSVVIGGAI
                     TRPKEIAQRFINVIK"
     gene            2606..3523
                     /locus_tag="VQT45_001774"
     CDS             2606..3523
                     /locus_tag="VQT45_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HET2360051.1"
                     /translation="MKDLTKYKGVIPAFYACYDENGEISQERVKSLVQYFIDKGVKGI
                     YVNGSSGECIYQSVEDRKQIIEAVMEVAKGKLTVINHVACNNTKDSIELAKHSESVGV
                     DAIAAIPPIYFKLPEYSIAAYWNAMSEAAPNTDFIIYNIPQLAGVALTGSLYATMRQN
                     PRVIGVKNSSMPVQDIQMFVAAGGEDYIVFNGPDEQYLGGRLMGAEAGIGGTYGVMPD
                     LFLKLESLIQERDLDTAKKLQYAINEVIYKMISGKANMYAVAKEVLRLNEKLDLGSVR
                     QPLEALAEGDLEVAKQAAELIQQARKEFL"
     gene            3551..5092
                     /locus_tag="VQT45_001775"
     CDS             3551..5092
                     /locus_tag="VQT45_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HET2360052.1"
                     /translation="MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGS
                     VPWYVTSVSIFATMLSPISFLGLAGNSYAGSWILWFAQLGMVVAIPLTIRFILPIFAR
                     IDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILI
                     ILMGAVAIVYSYTGGLKSVLWTDFIQGVILISGVVLALFVLMANIKGGFGAVAETLAN
                     GKFLAANEKLFDPNLLSNSIFLIVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKML
                     FTNGVLSLATATVFYLIGTGLYVFYQVQNAGSAASNIPQDQIFMYFIAYQLPVGITGL
                     ILAAIYAASQSTISTGLNSVATSWTLDIQDVISKNMSDDRRTKIAQFVSLAVGLFSIG
                     VSIVMAHSDIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMV
                     FIKYFLPPTAVSYWAYSLISISVSVVSGYIVSVLTGNKVSAPKYTTIHDIPEIKADSS
                     WEVRH"
     gene            5111..5569
                     /locus_tag="VQT45_001776"
     CDS             5111..5569
                     /locus_tag="VQT45_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2360053.1"
                     /translation="MIISEQSDFRRYASINKHFSKVCDFLENTNLTDLVDGKVDIDGE
                     NVFANCMIYLADGVPGDIFETHKKYLDIHIVVENTEKMAVTSPVRAQSRVPFSEEKDI
                     AFYDSKDYQIVELLPGNMLVTFEEDLHQPKIHCNDEPVKKLVIKVLNEEK"
     gene            5571..7793
                     /locus_tag="VQT45_001777"
     CDS             5571..7793
                     /locus_tag="VQT45_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HET2360054.1"
                     /translation="MKKNIKQYVTLGTAVVLSAFVANSVAAQETETSEVSTPELVQPV
                     APTTPISEVQPKSGNSSEVTVQPRTVETTVKDPSSATEETPVLEKNNVTLTGGGENVT
                     NELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEA
                     RDTSSNKNHLVSRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNF
                     LNIKDIKGIDYYMLGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHL
                     IYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKINIATSYSDDNGKTW
                     TKPKLTLAFDDFAPVPLEWPRDVGGRDLQISGGATYIDSVIVEKNNKQVLMFADVMPA
                     GVSFREATRKDSGYKQIDGNYYLKLKKQGDTDYNYTIRENGTVYDDRTNRPTEFSVDK
                     NFGIKQNGNYLTVEQYSVSFKNNKKTEYRNGTHVHMNIFYKDALFKVVPTNYIAYISS
                     NDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAFIYSDDN
                     GASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSTDAGTTWSAPEYL
                     KFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTNGRKHGQIWIGLINDDNTIDWRY
                     HHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNELHMKNVVPYITFKIEDLKKN
                     "
     gene            7833..8942
                     /locus_tag="VQT45_001778"
     CDS             7833..8942
                     /locus_tag="VQT45_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET2360055.1"
                     /translation="MVNYGIVGAGYFGADLARSMNKIEDAKVVAVFDPNHGEEVAQEL
                     GSDVCASLDELVAREDIDCVIVASPSYLHREPVVKAAQHGKHVFCEKPIALSYEDCKA
                     MVDACKENNVIFMAGHIMNFFNGVHHAKELITQGKIGKVLYCHAARTGWEEQQPTVSW
                     KKLRSQSGGHLYHHIHELDCIQFIMGGLPEKATMVGGNVYHKGENFGDEDDMLIVNLE
                     YSDDRYAVLEYGNAFRWGEHYVLIQGTEGAIKLDLFNTGGTLRVKGEGESHFLVHETQ
                     EEDDDRTAIYTGRGMDGAIAYGKPGVRCPLWLQTCIDKEMEYLHDIIKGGEITEEYEK
                     LLNGVAALESIATADACTLSVKEDRKVSLSEITNA"
     gene            9099..9989
                     /locus_tag="VQT45_001779"
     CDS             9099..9989
                     /locus_tag="VQT45_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2360056.1"
                     /translation="MKIIGIDIGGTTIKADLYNEFGTSLNQFKEIETIIDYDLGTNQI
                     LNQVCDLIGEYILNHSIDGVGISTAGVVNANTGEIIYTGYTIPGYIGVNFTFEIEKRF
                     GLSTFVENDVNCAALGELWKGQAKDKKNVVMVTIGTGIGGSIIVNGQIVNGFNYTAGE
                     VGYIPVGNSDWQSKASTTALIHLYQKKSLKTNQTGRTFFTDLRAGDKVAKETFEIFVE
                     NLTKGLLTITYLLNPEILILGGGILAKKDILLPEIQSSLAKNAMDNRFLPKNLVAATL
                     GNEAGRIGAVKNFLDRISNK"
     gene            10014..10337
                     /locus_tag="VQT45_001780"
     CDS             10014..10337
                     /locus_tag="VQT45_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360057.1"
                     /translation="MTNSVFSTMQDIENVATDIIKSYDNEIYTYKAVSQEELEKLEKS
                     YDEKSHEELVSIESNLEMKQQNLIDEVNKTIKENYEKIQYISSSRRGEFVEKIIGRVV
                     EKYGY"
     gene            10327..>11268
                     /locus_tag="VQT45_001781"
     CDS             10327..>11268
                     /locus_tag="VQT45_001781"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Produces ATP from ADP in the presence of a proton
                     gradient across the membrane. Subunit I is part of the
                     membrane proton channel; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HET2360058.1"
                     /translation="MAISQMKRISLLFSKSSLDDVLKTIQELESVQFRDLKVQDNWSE
                     ALEKDEVVFPTIQISHTSNSNHGVIEGNDALIYLMNQQQYLEATVEKLQEYLPKENTF
                     KLLQQPPITTSYEELEKFGKANVAEGVLKKVNRQINRVHELERHIQSNNEEIERLIKW
                     EKLEIIPAHLEQFFFCKGKVGTIPRTVDNRLYNSFLENNIEVQEIFSNDREYGVVVFY
                     QSSCSIDFDEYLFEPFDYSRKELPKQRVVDLDQENMQLITEKENIIASLQDSKNNLID
                     LQWQIDYILSIYARQISKNNLLSTPHLVALEGWIEETR"
BASE COUNT         3873 a         1616 c         2202 g         3577 t
ORIGIN      
        1 gaatgcctca aagtccatgg gtagaaagga ttgtgcaggt attagattta gattatgaag
       61 atttatttcg gaggtaatta tgaaaagaat aattccagtt tatatattcc aacaagtaaa
      121 tgtcctattg gtatctctat acttattgaa atttctttgt agcgatgagt taactatact
      181 acagattctc tatggagcgt cactcatttc ttttttatgg atgtatggtc aacgaaaaca
      241 agtgatcaag gttaatatga aaactaggat acaatggctt ggtattggat tcgttagcct
      301 actgattata agtctatgtt ttagtctaat ccatgcgcaa gaaagcacga atcaagcaaa
      361 cttaattgga cttcaacatc aaattccttg gttttcattt ttattgtttt taatcaatgc
      421 gagtatggtt gaagaatttc tgtatagaga aattttatgg aacttggtta gaaaattaga
      481 tattcgagtt gctttgacaa gtgttttatt tgccttagca catcatccag gaaccattat
      541 agcttggtgt ttgtatgtat cgctggggat gtttttaggg cttgtacgct acaaattgga
      601 cttatggggc agtatggggc tacatttggt gtggaaccta ctagtttata gtttgctgct
      661 tttttaaaat aagtgatctg atttatctca taaatcagta gtttttatag gattattttt
      721 aattcggaaa caaaaatgta ttaacagcat aaaataaaga aactaggaac atttttttta
      781 ttttttagaa ataaaatgtt gtatagaaat tccgaaagaa ataataaaat caaaataaaa
      841 attaataaaa taggtatatt tgaacatatt gacgtcgaca aatgttcttg caagacataa
      901 aatacaaata aaaagaataa aaaattttta tatttttata tttgttgttc tgttataaaa
      961 tgaaagaaat tagaaactag tttctaaatc atgaaaaata ttgaaaaaaa aaaaataagt
     1021 gttaaaataa agaatgtaaa cgtttacttc aataaaggag ctcatatgtt actgcaaaaa
     1081 gaactaattc caatgataga agctaactta ccaaatatgg catatgctga aaaagacatt
     1141 gctaaattct tcttaaaaca gcaacctctg aataattatt catgtaaggc attgtgcgaa
     1201 tgccttaatg tatccaaagc aacattgact cgatttgcga aaaaatgtgg ttttaaaggt
     1261 tttagacaat tcattttcaa ataccaagag atgattcgtg agaaagaaaa gttagcattg
     1321 tatacagagg ctacagaaaa agttttatcc gactatgaag aaatgttgag aaaaacttac
     1381 acggttcttg atgaagttca acttgagcgt attgctgaga tgatagaaac tgctgagcgt
     1441 gtatatcttt atggtaaagt aagttctgtt cttgctttac aagaaatgaa gatgagattt
     1501 atgcgtctcg gagtcattgg tgaagtatta tcagacgagg atatgatttt gtggaatagc
     1561 ttattactta atgaaaattg ccttgtcatt ggagcatccg tttcaggtca aactgatatt
     1621 gtactagaag gtcttcaaaa agctgcggat aaaggcgcta aaacagtttt aatgactaca
     1681 agaaaatttg acgaagaaga ttgtttcttt gatgaactat tgttattagc ttcgaccaat
     1741 catctctcgt atggcaatcg catatcacct cagtttccaa tacttttaat tacagactgc
     1801 ttattctctc attatctgga aagtccagag agacaatatt attacaatca aactattatc
     1861 cataaggagg aataataaaa tgagtcaaat ttggactaaa gaaaaattta taagtcaagt
     1921 ccatggtgga gtcattgttt cttgtcaagc tttacccggt gaaccccttt ataatgaaga
     1981 atttagcttg atgcctttta tggctaaagc agctttagag gcaggagcag tgggcattcg
     2041 cgcaaattct gtgcgtgata ttaaagcaat tcagaaagta gtagatttac caataattgg
     2101 aattatcaaa agagattatc cacctcaaga accatatatt actgctacga tgaaagaagt
     2161 agatgaactt gtagaatgcg gaacaacagt cattgcattt gatgcaactt taagaccaag
     2221 atatgatggc ttagttatca atgaatttat caaaaaaata aaagaaaaat atcctaatca
     2281 attgttgatg gcggatgtaa gtaattttga tgaaggtctc tatgcattta aatcaggcgt
     2341 tgattttgtt ggtacaacat tatcagggta cacaagtaca agtgtacaat cagatgagcc
     2401 tgattttgaa ctaatgaaaa aattggctga ttttaatatt ccggtaattg ccgaaggaaa
     2461 aattcattat ccagaacaat taaaaaaagc ttatagttta ggtgttacca gtgttgtcat
     2521 tggtggagcg attacacgtc caaaagaaat tgctcagcga tttattaatg tcatcaaata
     2581 aaaaacaata taaaggagaa atctgatgaa agatttaact aaatacaaag gcgttattcc
     2641 tgcattttat gcttgctatg atgaaaatgg tgaaattagc caagaacgtg taaaatctct
     2701 ggtgcaatat ttcattgaca aaggtgtaaa aggtatctat gtaaatggtt cttcaggtga
     2761 atgtatttac caaagtgtag aagatcgtaa acaaattatt gaagctgtta tggaagttgc
     2821 taaaggtaaa ttaacagtta tcaaccatgt tgcatgtaat aacacgaaag atagtattga
     2881 attggcaaaa cattcagaaa gtgttggagt cgatgctatt gctgctatcc cacctattta
     2941 cttcaaattg ccagaatatt caattgcagc atattggaat gcaatgagtg aagctgcgcc
     3001 aaatacagat tttatcattt ataatattcc acaattggca ggggttgcgt tgactggtag
     3061 tttgtatgca acaatgcgtc aaaatcctcg tgtgattgga gttaaaaatt cttctatgcc
     3121 tgtacaagat attcaaatgt ttgtagctgc aggtggagaa gattacattg tattcaatgg
     3181 tccagatgaa caatatcttg gtggtcgctt gatgggagca gaagctggta ttggtggtac
     3241 ttatggcgtt atgccagatt tgttcttgaa attggaaagt ttgattcaag aacgagattt
     3301 agatactgct aaaaaacttc aatatgctat caatgaagtt atctataaga tgatatcagg
     3361 taaggcaaat atgtatgctg tagcaaaaga ggttttgcgt ctaaatgaaa aacttgattt
     3421 aggttctgtt cgtcaaccct tagaagcatt ggcagaaggt gacttggaag ttgcaaaaca
     3481 agcagcagaa cttattcaac aagcacgaaa agaattttta taataaataa aatcaatatg
     3541 gagatatgtt atgggcacaa caggatttac aataattgac ttaattatct tgattgttta
     3601 tttacttgcg gtgttggttg caggtatcta tttctctaaa aaagagatga aaggaaaaga
     3661 gttcttcaaa ggagatggtt cggttccttg gtatgttact tcggtatcca tttttgccac
     3721 aatgctcagt ccgatttcct tcttgggact cgctggtaac tcttatgcag gtagctggat
     3781 tttatggttt gctcaattag ggatggtagt agctattcca ctgacaattc gttttatctt
     3841 acctatcttt gcacggatag acatcgatac ggcatatgat tacttggata aacgttttaa
     3901 ttctaaagca cttcgtatta tttcagcact cttgtttatt atttatcaat tgggacgtat
     3961 gtctatcatt atgtacctcc catcagctgg tttatcagta ttgacaggaa ttgacatcaa
     4021 tattttgatt attttgatgg gtgcagttgc aattgtttat tcttacactg gtggtctaaa
     4081 atccgtatta tggacagact ttattcaagg tgtgattctg attagtggtg tcgttttagc
     4141 tttatttgta ctgatggcta atattaaagg tggctttggt gcagtagcag aaacattagc
     4201 aaacgggaaa ttccttgctg caaatgaaaa acttttcgat cctaacttgc tttcaaactc
     4261 catcttttta attgtgatgg gttcaggctt tacaatcttg tcttcctatg cttcatctca
     4321 agatttggtt caacgtttta ctacaacaca aaatattaag aaacttaata agatgttgtt
     4381 cacaaacggt gtcttgtcac ttgcaactgc aacagtcttt tacttgattg gtacaggctt
     4441 gtacgtattc tatcaagtac aaaatgcagg tagtgcagct agcaatatcc ctcaagacca
     4501 aatctttatg tactttattg cataccagtt accagtaggt atcacaggtt tgattttggc
     4561 agcgatttat gcagcatctc aatcaactat ttcaacaggt ttgaactctg ttgcaacttc
     4621 atggacattg gatattcaag atgtcatttc taaaaatatg tcagacgatc gtcgtacgaa
     4681 aattgcacaa ttcgtatctc tagcagtagg tttattctca attggtgttt ccattgtcat
     4741 ggctcactca gatattaaat ctgcatacga atggttcaat agcttcatgg gacttgtact
     4801 tggtctactt ggtggtgtat ttattcttgg atttgtttct aaaaaagcaa ataaacaagg
     4861 tgcttatgca gcgctgattg tatcaactat cgtcatggta tttattaaat acttccttcc
     4921 tccaacagct gtgagctact gggcatattc attgatttca atctctgtat cagtagtttc
     4981 aggttatatt gtatctgttc ttactggaaa taaagtatct gcacctaaat atacaacgat
     5041 tcatgatatt ccagaaatta aagcggattc aagttgggaa gttcgtcact aatagaaaag
     5101 agaaaataat atgattattt ctgaacaatc tgattttaga cgatatgctt ctatcaataa
     5161 acatttttca aaagtctgtg attttttaga aaatacaaat ttgacagatt tagttgatgg
     5221 aaaagttgat attgacgggg aaaatgtttt tgcaaattgt atgatctatc tagctgatgg
     5281 agtcccagga gatatttttg aaactcataa gaaatattta gatattcata ttgttgttga
     5341 aaatactgaa aaaatggcag taacttcccc agttcgtgcc cagtcacgtg taccttttag
     5401 cgaagaaaag gatattgctt tttacgatag caaagactat caaattgttg aattgcttcc
     5461 agggaatatg ttggtgactt ttgaagaaga tcttcaccaa ccaaagattc attgcaatga
     5521 tgagcctgtt aaaaaacttg ttattaaagt tttaaacgag gaaaaataaa atgaaaaaaa
     5581 atattaaaca atacgtaacc ttaggtactg cagtggtatt atcagcattt gttgctaact
     5641 cagttgcagc tcaggagact gaaacttctg aagtatcaac accagagttg gtgcaacctg
     5701 ttgcaccaac gactccgatt tcggaagtac aacctaaatc gggtaactct tcggaagtta
     5761 ctgtacaacc tagaacagtc gaaactactg ttaaggatcc atcttctgca acggaagaaa
     5821 ctcctgtctt agaaaaaaat aatgttactt taacaggggg cggagaaaat gttactaatg
     5881 agttaaagga taaatttact agcggtgact ttactgtagt gattaagtac aatcagtcta
     5941 gtgagaaagg cttacaagct ctgtttggaa tatctaattc taaacccggt caacaaaata
     6001 gttatgtaga tgtgttcctt agagacaatg gtgaattggg aatggaagcg cgtgatactt
     6061 cttccaataa aaatcaccta gtatccagac ctgcttcagt ttggggtaag tacaaacaag
     6121 aagctgtgac taacactgtt gcagtagtag cagattcagt caaaaaaaca tattctttat
     6181 atgcaaatgg tacaaaagta gtagaaaaga aagtggataa cttcttaaac atcaaggata
     6241 ttaaaggtat tgattactat atgcttgggg gagtgaaacg tgcaggaaaa acggcgtttg
     6301 gttttaacgg aacactagaa aatatcaaat tctttaatag tgcattggat gaagaaactg
     6361 ttaaaaagat gacaacaaac gctgttactg gacatttaat ttatacggct aatgatacaa
     6421 caggttctaa ctatttccgt attccagttc tgtatacttt tagcaatggt cgggtatttt
     6481 caagcattga cgctcgttac ggcggaactc atgatttttt gaataaaatt aatattgcta
     6541 caagttatag tgatgataat ggtaagacat ggactaaacc aaaattaaca ttggcattcg
     6601 atgattttgc gccagtacca ttagaatggc ctcgtgatgt tggtggacgt gacttacaaa
     6661 tcagcggtgg tgcaacctat attgactctg ttattgttga aaaaaataac aaacaagtac
     6721 tcatgtttgc ggatgtgatg cctgctggag taagttttag agaagctact agaaaagatt
     6781 caggttataa acaaattgat ggtaattatt accttaaatt aaagaaacaa ggtgatactg
     6841 attacaatta tactattcgt gagaatggta ctgtatacga cgatcgtacc aacagaccaa
     6901 ctgaattttc agtagataaa aatttcggta ttaaacaaaa tggtaattat ttgacagtag
     6961 agcaatattc ggtttcattt aaaaataata aaaagactga atatcgtaat gggactcacg
     7021 tccatatgaa tatcttctac aaagatgcat tgttcaaagt agtgccaacg aactatattg
     7081 catatatttc tagcaatgat catggcgaat cttggtctgc accaacttta ttacctccta
     7141 taatgggact taatcggaat gcgccttatt tgggtcctgg acgtggaatc attgaaagct
     7201 caactggacg tattcttatt ccgtcttaca ctggtaaaga gtctgcattc atttatagtg
     7261 acgataatgg agcatcttgg aaagttaaag ttgtgccact tccttctagt tggtcagcag
     7321 aagcacaatt tgtagaattg agtccaggag taattcaagc atacatgcgt acaaataatg
     7381 gtaaaattgc atatttaaca agtacagacg caggtactac ttggagtgca ccggaatatt
     7441 tgaaatttgt ttcaaatcca agttatggaa cacaattatc aatcatcaat tatagtcaac
     7501 tgattgatgg taaaaaggct gtcattttaa gtactccaaa ctccacaaat ggtcgtaaac
     7561 acggacaaat ttggattggt ctaattaatg atgataatac aattgattgg cgttatcatc
     7621 acgacgttga ttatagtaac tatggatact catattcaac attgacagag ttaccaaatc
     7681 atgaaattgg attgatgttt gaaaaatttg attcatggtc tcgtaatgaa cttcatatga
     7741 aaaatgttgt accatatata acatttaaga ttgaagatct gaaaaagaat taaagctgaa
     7801 atttgaaaat atataaaaag aggataaaaa ttatggtaaa ttacggtatt gttggagctg
     7861 gatattttgg agctgattta gctcgctcaa tgaacaaaat tgaagatgca aaagtggttg
     7921 cggtatttga cccaaatcat ggagaagaag ttgctcaaga gttgggatca gatgtttgtg
     7981 caagtttaga tgaacttgta gcacgtgaag atattgattg tgtgatcgta gcttcaccta
     8041 gctaccttca ccgtgaacca gttgtgaaag ctgctcaaca tggcaaacac gtattttgtg
     8101 aaaagccaat tgcattgtct tatgaagatt gtaaagccat ggttgacgca tgtaaagaaa
     8161 ataatgttat ctttatggct ggtcacatca tgaacttctt taacggtgta caccatgcta
     8221 aagaattgat tactcaaggt aaaatcggta aagttcttta ttgccatgcc gctcgtacag
     8281 gttgggaaga acaacaacca actgtatcat ggaagaaact tcgttctcaa tctggaggac
     8341 atttgtacca tcatattcat gaattagatt gcattcagtt tatcatggga ggacttcctg
     8401 aaaaagcgac aatggtagga ggcaatgtat atcataaagg tgaaaacttt ggtgatgaag
     8461 atgatatgct cattgtaaac ttagaatact ctgatgatcg ttatgctgtt ttggaatatg
     8521 gtaatgcttt ccgttggggt gaacactacg tcttgattca aggaactgaa ggagctatca
     8581 aacttgattt gttcaatact ggaggtactc ttcgtgttaa aggtgaagga gaatcacact
     8641 tcttagttca tgaaactcaa gaggaagatg atgaccgtac agctatctat accggtcgtg
     8701 gtatggatgg agcaattgcg tacggtaaac caggagtacg ttgcccatta tggttgcaaa
     8761 catgtattga taaagaaatg gaatatctac atgacatcat taaaggtgga gaaattacag
     8821 aagaatatga aaaacttctc aatggtgtag ctgctttaga atcaatcgct accgctgatg
     8881 catgtacttt atcagttaaa gaagatcgaa aagtaagtct ttcagaaatc acaaatgctt
     8941 aacttttgta aaacagaata gtaaattctt atcattatat aatttctaaa gttctgtgat
     9001 acaactcatt gaataaagaa atagagatgg gactgggata atgcccagtc ccatttttta
     9061 tcaaaaagta atgagatcaa aaatgtggga gtgatgaaat gaagattata gggatcgata
     9121 ttggcggaac aacaattaaa gcagatttat acaatgagtt tggaacgagt ttaaatcagt
     9181 tcaaagagat agaaacaatt attgactatg atttgggaac gaaccagata ttaaatcagg
     9241 tctgtgattt aattggtgag tatattttaa atcattcaat tgatggtgtt gggatttcca
     9301 ctgctggagt tgttaatgct aatacaggag agatcatcta tacaggctat acaataccag
     9361 ggtatatcgg agtaaacttt actttcgaaa tagaaaaacg ttttgggttg tctacttttg
     9421 ttgaaaatga tgttaattgt gctgcattag gtgaattgtg gaagggacaa gccaaagata
     9481 agaaaaatgt agtaatggtt actattggaa caggtatagg aggcagtatt attgtcaatg
     9541 gacaaattgt taacggattt aactatactg ctggtgaagt aggctatatt cctgtaggta
     9601 attcggattg gcaaagcaaa gcctcaacaa ccgcattgat tcatttatat caaaagaaaa
     9661 gcttgaaaac taatcaaact gggcgtactt tctttactga tttaagagct ggagataaag
     9721 tcgctaaaga aacttttgaa atttttgtag aaaatctaac aaaaggttta ttaacgatta
     9781 cttatctact taatccagaa attctcatat taggaggtgg gatcctggct aaaaaggata
     9841 ttttgttacc tgaaattcaa agttctttag ctaaaaatgc aatggataat aggtttttgc
     9901 ctaaaaatct tgtggcagct acattaggaa atgaagctgg tcgtatagga gctgtaaaaa
     9961 atttcttaga tagaatttct aataaatagt atgaaagata aggaggtgtc acaatgacta
    10021 actctgtatt ttcgacaatg caagatattg agaatgttgc aaccgatatt ataaaatcat
    10081 atgataatga gatttatact tataaagctg tttcccaaga agaattggaa aaactagaaa
    10141 aaagttatga tgaaaaaagt cacgaagaat tagtttcaat agaaagcaat ttagaaatga
    10201 aacaacagaa ccttattgat gaggttaata aaacaatcaa ggaaaattat gaaaagattc
    10261 agtatatttc atcaagtagg agaggagaat ttgtagaaaa aattattggt agggtggtag
    10321 aaaaatatgg ctattagtca gatgaaaaga atttctctac tattttctaa aagtagtctt
    10381 gatgatgttt taaaaactat tcaagaacta gagtcagtgc agttccgtga tttaaaggtt
    10441 caggataact ggtcagaagc tctagaaaaa gatgaggttg tatttccaac tattcaaatt
    10501 tctcatactt ctaattccaa tcatggggtt attgaaggaa atgatgcctt gatttatttg
    10561 atgaatcaac aacaatattt agaagcaact gtagagaaat tacaagaata cctaccgaaa
    10621 gaaaacacgt ttaaattatt acagcaacct ccgataacga cctcttatga agaattagaa
    10681 aaatttggta aagctaatgt tgctgagggt gttcttaaaa aagtgaatcg tcaaataaac
    10741 agagttcatg aattagaaag acacattcaa agtaataatg aggaaataga gagattaata
    10801 aaatgggaaa aattagaaat tattcctgcg catttagaac aatttttttt ctgtaaagga
    10861 aaagtcggaa caattccaag gactgtagat aatcgcttat acaatagttt tttagaaaac
    10921 aatattgaag ttcaagaaat attttctaat gatagagagt acggtgttgt tgttttctat
    10981 cagtccagtt gctctattga ttttgatgaa tacttatttg aaccatttga ttattctaga
    11041 aaggaattac cgaagcagcg agtagtagat ttggatcaag aaaacatgca gttaataact
    11101 gaaaaagaga atattatcgc atcgttgcaa gattcaaaga ataatttgat agatttacaa
    11161 tggcaaattg actatatttt atctatctat gctcgtcaaa tctctaagaa taaccttttg
    11221 agcactccgc atctagttgc actagaagga tggatagaag aaactcgt
//
LOCUS       DAVAZT010000061        11228 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVAZT010000061 DAVAZT010000000
VERSION     DAVAZT010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11228)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11228)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11228
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.061"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            1..502
                     /locus_tag="VQT45_001782"
                     /pseudo
     CDS             1..502
                     /locus_tag="VQT45_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(618..1421)
                     /locus_tag="VQT45_001783"
     CDS             complement(618..1421)
                     /locus_tag="VQT45_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HET2360059.1"
                     /translation="MQSTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRSEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(1700..2455)
                     /locus_tag="VQT45_001784"
     CDS             complement(1700..2455)
                     /locus_tag="VQT45_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HET2360060.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(2525..5176)
                     /locus_tag="VQT45_001785"
     CDS             complement(2525..5176)
                     /locus_tag="VQT45_001785"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HET2360061.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYSTTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPKFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTDDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNEAGEIYVGEEAPAGDGWKQDEDVLDTWFSS
                     ALWPFSTMGWPNTETTDFKRYYPNSTLVTGYDIIPFWVSRMIFQGIEFTGKSPFKNAL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIDKYGTDSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAEYPTVNPAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLVDLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(5169..5747)
                     /locus_tag="VQT45_001786"
     CDS             complement(5169..5747)
                     /locus_tag="VQT45_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET2360062.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYQLMYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(5747..6217)
                     /locus_tag="VQT45_001787"
     CDS             complement(5747..6217)
                     /locus_tag="VQT45_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2360063.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGYG
                     IVVKGTDKIVGSVDFNHRHEDDVLEIGYTLHPDYWGRGYVPEAARALIDLAFKDLGLH
                     KIELTCFGYNLQSQRVAEKLGFTLEARIRDRKDAQGNCCDDLRYALLKSEWEVI"
     gene            complement(6204..6782)
                     /locus_tag="VQT45_001788"
     CDS             complement(6204..6782)
                     /locus_tag="VQT45_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HET2360064.1"
                     /translation="MKQSFKTNKLYYGFPVFILGYQDQNFGYNITTCSSSYSLGDWVV
                     IGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEKLERLGVHYEISERTQ
                     TPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDEKGHFKNQLFAPTYFM
                     GDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(7065..7460)
                     /locus_tag="VQT45_001789"
     CDS             complement(7065..7460)
                     /locus_tag="VQT45_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET2360065.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            complement(7556..7810)
                     /locus_tag="VQT45_001790"
     CDS             complement(7556..7810)
                     /locus_tag="VQT45_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HET2360066.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            complement(7819..9153)
                     /locus_tag="VQT45_001791"
     CDS             complement(7819..9153)
                     /locus_tag="VQT45_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HET2360067.1"
                     /translation="MTDEWIHILRDILLELHNGASPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVLDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYELMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTVKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKRLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(9153..9386)
                     /locus_tag="VQT45_001792"
     CDS             complement(9153..9386)
                     /locus_tag="VQT45_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HET2360068.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLTGTPMDKIVRTLEANGYEVIGLD"
     gene            9417..9491
                     /locus_tag="VQT45_001793"
                     /pseudo
     CDS             9417..9491
                     /locus_tag="VQT45_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            9480..9605
                     /locus_tag="VQT45_001794"
     CDS             9480..9605
                     /locus_tag="VQT45_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004238277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysyl-tRNA synthetase"
                     /protein_id="HET2360069.1"
                     /translation="MDRTDEVSNHTYSKVKLTWFEEIFEEYKMILLLILYHMERD"
     gene            complement(9655..9795)
                     /locus_tag="VQT45_001795"
     CDS             complement(9655..9795)
                     /locus_tag="VQT45_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360070.1"
                     /translation="MKFFWTILAILFIKPIIGIVKFFWMIISFAVQLLFYKILDWFFK
                     LI"
     gene            complement(9792..9974)
                     /locus_tag="VQT45_001796"
     CDS             complement(9792..9974)
                     /locus_tag="VQT45_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360071.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKDDHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(9976..10759)
                     /locus_tag="VQT45_001797"
                     /pseudo
     CDS             complement(9976..10759)
                     /locus_tag="VQT45_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         3311 a         2470 c         2063 g         3384 t
ORIGIN      
        1 aaggatctaa aacaatggaa aagtgctaca cagatgtgac tgaatttgcc attccagcaa
       61 gtactcaaaa gctttactta tcaccagttt tagatggctt taacagcgaa attatcgcct
      121 ataatctttc aacttcaccc aacttagaac aagtacaaac aatgttggaa caggcattca
      181 cagagaagca ctacgagaat acgattctcc atagtgacca aggctggcaa taccgacacg
      241 attcttatca tcggttccta agagtaaggg aattcaagca tctatgtcac gcaagggaaa
      301 cagccaagac aacggtatga tggagtcctt ctttgggatt ctgaaatcgg aaatgtttta
      361 cggttatgag aagtcgtttc agtcgcttaa gcaattggaa caagccatta tagactatat
      421 tgattactac aacaataaac gaattaaggt aaaactaaaa ggacttagcc ttgtgcaata
      481 cagaactaaa tccttcggat aaattatttg tctaactttt tggggtcagt acacctaaaa
      541 ctttgatgat atacgttttc ttgtgagaat atttacttca tttttgccta aaattcaatg
      601 tttactcagt atttggatta tgaaaaatcg aggtctaaat ctagatacat tttttctgaa
      661 gacaaatcat tttgaccacc gagcaagaga ttttcaaaaa aagctgttaa aaactcagaa
      721 cgtcgctgta aaatctttgc attatctaat accaaggcat cacgaaaata tttggaatgt
      781 tgctgaaatg gtgtattatc aatatcaaaa ccaaactcac gaagatactg aatcaaaaag
      841 accgttactg tccgagtgtt tccttcgcga aatggatgaa tctgccagat tcctgaaata
      901 aaatgctgga tttgtttaac cacatccgcc tgagttagtg tcgcatatgc aacttgtttt
      961 tcctgattaa aatcataatc taaggtcatt tgaatcatgg agtaatcaga gtacacaaca
     1021 ctttcaccat tcaaaacagg ttcattcttt gtgatattgg tctgacgaaa ttgccccacc
     1081 ggaatagagg gttcaaatat atcttgaaac aactccttat gaatagcaag taaggtcgca
     1141 ggactaaagc taaagcctct tcgagacaat agttctacaa tacgtagaga aaccaagtct
     1201 gcctcttccg tacttgcatc aatagtatgg tgataagccg ttgcatcctc ataaacctgc
     1261 tcataagtca gttctccccg ggactgtttc tcagccaaag attccatata cgctgatggc
     1321 actagattgt caactttctg cagaccaaaa cctatccgcc ataaatcacg cttcgcttca
     1381 taagacaagt ttggattgtc aatgttgtaa gttgattgca tagaaatatc ctttcaattg
     1441 tttttcttca ttaccagtaa atcacgaaat tggttggaaa ctggcttaaa ctataaaaag
     1501 tcctcacaat aggttctatg atatatatat atatacttca tgtaaataat aaaagagtta
     1561 taatcagcac tactgataaa ttcaataccg atttcgccat cttaaaactt agtcaaacga
     1621 ataccgttga tttccagttc attaagtcgt tgacctgtca agacttctcg ttccttcaac
     1681 tggaaaagtt aagggggaac taatacaaat cctctacgct tctatattca atgatttcat
     1741 ttttgataat attcttttta aactcaaaat gttttaaagg attatcgatt aacactaact
     1801 ttggaatatc atctagattt gtgaccaagg ataaaataaa atccgattga aactccttga
     1861 ctttttcaaa ttcttttgca gttaaacgca cacgcccctt agattttcgg atacctttta
     1921 cttcggcaag gtaagaatac tcttggacat ctacctgaaa gtcatatcca tcaccataaa
     1981 gacgggcatc ggttaactgt ccaccttgga atttttcttc tttatcaaaa tgaaggataa
     2041 aataattctc agcctccatt cccgtttcct gtagacgttt gaatttagtt cgaactattg
     2101 gtttttcaac gatggttatg cctgttttct tcccttcact ggcaagtaac attttaacta
     2161 tttcagcata actatgaaca tcttcatttc caaacatcat atcaattaaa tctttacgaa
     2221 aacgataaac ttcagctttc tgccaccaac cttttcgatt attgtcaaaa taaggatcaa
     2281 ataaatccat tctatttttt acaactccag ttgtttcagc aattcccaga gaaaccacat
     2341 agcgataaaa ctccgacttg ctagagcatt gaaattcttt tataaaaagc ttgtcaaact
     2401 tggcaagacc gtagccaatt aaatttaaca attcataatg agggtgtttg gacatcactt
     2461 tctccatcaa tagatattga tttcattata ccaaaaaaca cggctcatca ccgtgtttct
     2521 gtgtttattt caccaacttc ttcatctcat caatacgtgc tacggtcgca tcatacttag
     2581 cttggtaatc tgcttgcttg tcgcgttctt tttggacaac ttctggttta gcgttggcga
     2641 cgaagcgttc gttgctgagt tttttgccaa ccatgtcgag ttctttctgc catttggcaa
     2701 gttctttttc cagacgtgcc aattcttctt cgacattcaa gaggtctacc agtggcaaga
     2761 agatttcggc tcctgtgatg acgcttgaca tagccagttc aggtgcaggg atggttgatg
     2821 cgatttccaa gtgttcagga tttgtgaaac gtttgatgta gttgacattg ctgttaaaga
     2881 aggcttccaa gtcgctatcg cttgtcttaa caaggatagt gataggcttg cttggagcaa
     2941 cgtttacttc cgcacgcgca ttacgaacgg cacggatcaa gtctttaagg ctttccacac
     3001 cagtgtgagc agcaaggtct tcaaaggctg ggttgacagt tgggtattct gctgtaacga
     3061 tagatccttc tgagatttgt ccaaagattt cctctgtcac aaatggcatg attgggtgaa
     3121 ggagacgaag gatcttgtcc aaagtgtata gtagaacaga acgtgtgatg actttctctt
     3181 cttcgttatc gctataaagg acttccttgg tcaactcaac ataccagttg gcaaattctt
     3241 cccagatgaa gttgtaaagg atatgaccag ccacaccaaa ctcgaactta tcaaagtttt
     3301 cagtaacttt tgcaatggtt tcgttgagat tgtggagaat ccagcggtcc gtcacattac
     3361 cagcctcacc tgttgcaact tttgtgacat tgtcatgcgc cacatccagc gtcaaacctt
     3421 cattgttcat gaggatatag cgagaaatgt tccaaatttt gttaataaag ttccatgaag
     3481 catccatttt ctcgtaagag aaacgaacgt cttgaccagg agctgagccg tttgacaaga
     3541 accaacgaag actatctgta ccatatttat caataacatc cattgggtca atgccatttc
     3601 caagagattt agacatctta cgtccttctt catcacgaat tagaccatgg ataagagcat
     3661 ttttaaatgg gctctttcct gtaaattcaa ttccttggaa aatcatgcgt gatacccaga
     3721 aaggaataat atcatagcct gttacgagtg ttgaatttgg atagtagcgt ttaaagtcag
     3781 tagtttcggt attaggccag cccatggttg agaagggcca gagggcagag ctgaaccaag
     3841 tgtcaaggac atcttcgtcc tgtttccagc catcgcccgc tggggcttcc tcgccgacat
     3901 agatttcgcc tgcttcatta taccaagcag ggatttggtg accccaccag agctgacggg
     3961 aaatcaccca gtcgtggaca ttttccatcc attgcaggaa ggtgtcgttg aagcgcggtg
     4021 ggtaaaattc caccttgtca tctgtgtctt ggttggcaat ggcgttcttg gccaattggt
     4081 ccatcttgac gaaccattga gtagacaagc gtggctcaac tacgacacct gtccgttctg
     4141 agtgaccgac tgaatggaca cgtttttcga ttttgacaag ggcaccgatt tcttccaact
     4201 tagcaacgac tgccttacga gcttcaaaac gatccatgcc tgaaaattca aaggcaagct
     4261 cgttcatagt tccgtcgtcg ttcatgacgt tgacttgtgg caagttatga cgttggccaa
     4321 ccaagaagtc atttggatcg tgggcaggtg tgattttcac gacaccagta ccaaacttag
     4381 gatctgcgtg ctcatcacca acgattggga ttaatttatt agcaattgga aggatgacat
     4441 ttttaccaat caagtccttg tagcgcgggt cttctgggtt gaccgcaacc gcaacgtccc
     4501 caaacatggt ctcaggacga gttgtagcaa cttcaagggc gcgtgaacca tcttccagca
     4561 tgtaattcat gtgatagaag gcaccttcga cgtccttgtg aataacctcg atatcagaaa
     4621 gggctgtgcg agctgctggg tcccagttga tgataaactc accacggtag atccagcctt
     4681 tcttgtaaag gtccacaaag accttacgaa cagcttttga caaaccttcg tcaagagtga
     4741 aacgctcacg agagtagtct acagagagcc ccatcttgcc ccattgttcc ttgatagtag
     4801 tggaatattc gtctttccat tcccagactt tcgtcaagaa agactcacga ccaaggtcat
     4861 agcgggaaat gccctcacca cgcaagcgct cctctacctt agcctgagtg gcaatccctg
     4921 cgtggtccat cccaggaagc caaagggtat caaaaccttg catgcgtttt tgacggatga
     4981 taatatcttg caaagttgta tcccaagcgt gaccaaggtg aagtttacct gtaacgtttg
     5041 gtggtggaat aacgattgaa taaggcttag ccttttgatc gcctgaaggc ttgaaaacat
     5101 cagcatcaag ccatttttgg taacgaccag cctcaacctc ggctggattg tatttagatg
     5161 aaagttcttt agacatgtgt gtgtcctttc tctattttgt ttattttatt ttgaatttgc
     5221 ttagcagctt cttctgcaga caaattcgta ttatttattt taaagtagtg gtgcaactca
     5281 ttcggttgat attgggaatt taattgaagt gtttcagcgg tctctaaaat ttctctttca
     5341 gatacctcaa tatgtcgttt taagggtttg tgctttaatc gattctccgt tcgatttcga
     5401 cgtatgcact cttcaagact tgtttccaac tcaacaaaaa gaatctcttg atgataatca
     5461 tccaacaaat tctgaatttg ctttaaatac atcagttgat actgatttga aaaatcaatt
     5521 acatctgtta aaattactga tcgctgattt cttgcacttg ctccaaggaa tgaaaaagtg
     5581 attccacgaa caaattccca catttcctct gtatagtcct gatagatttc tagtgcaaaa
     5641 tcaatggctt gatggttata aaatagggta gcatccgtca gtcgagataa ttcttgacca
     5701 atggtcattt ttcctgatgc tggagcacca atgatgaaaa gatgcatcaa atcacctccc
     5761 actcactctt cagcaaggca tatctcaaat catcacagca gttgccttga gcatctttac
     5821 ggtctcttat gcgagcttcg agggtaaagc caagcttttc cgcgactcgt tgactttgaa
     5881 ggttatatcc aaagcaagtt agttcaatct tgtgaagacc caaatcttta aaggctaagt
     5941 caatcaaggc acgcgcagct tctggcacat aacctcgccc ccaatagtct gggtgtaagg
     6001 tatagccgat ttccagcaca tcatcttcat ggcgatggtt gaaatcgaca gagccaacga
     6061 tcttatccgt tcctttgacg acaatcccgt agcctgctgg ataggcgacc tctggcaaac
     6121 tagcatagtc aaagatatcc tcagcatccg ccacagtacg gactcgtaaa acgagacgtt
     6181 ctgtttcgat tttatctggc agctcagttc ttgccatcct tcttcctcgc ttttttgatg
     6241 aaactgccct tcatatctac acgcttatcc agatagcgat aaacgcgctg atatccatct
     6301 cccatgaaat aggttggggc aaacagttga tttttaaaat gtcccttttc atccaggagt
     6361 tctggggcaa caagtcgctc aagaatcttg gcaaagatgt ggcaaatacc gtcttcctca
     6421 acaatcctat ctacccgaca atctaaaaca agtggacagg cgtctaaaat aggagtctga
     6481 gttcgttcag aaatttcata atgcactccc aaacgttcca atttctcctg atgactgata
     6541 aaaccagcct gctccatcgc aagcatagaa gtttcatcag aaatattcac agtaaatttt
     6601 tgatactgtt tgatctgctc tgcggcattc tctctcgcaa cgactccaat cacaacccaa
     6661 tctcctagac tatacgagga actacaggtc gtgatgttat agccaaaatt ctgatcttga
     6721 tatcctaaaa taaaaacagg aaaaccataa tatagtttat tagttttaaa tgattgtttt
     6781 ataacaacct cctttgacta agacacaaaa gaaaagccct gccatctaca tgacagggac
     6841 gaatgtattt atccgcggta ccacccaatt tcgggccaag cccgcatctt tagtctttaa
     6901 aataaaaaga cagaaatatt tcattttttc agtcattagc aaccagtttt gacacatttg
     6961 tggacttctc agcgccgcca ctttctgtaa aatgtgggat tcaaaacacc tctaatagct
     7021 ctattgtagc aagtttttct cggaaatgca aggctcaaga aaaattactt gaacttgatg
     7081 ccattttctt tcaatttctt gatggtagct gggccgattc ctttcaaggc aaggagttct
     7141 ttttcagtcc agtttttgaa atctgaagca gacttgattc cttcatcata gaaagtcttg
     7201 gcacgatcaa gtggaagtcc acccaagttt gctgcaaaat cttctacaga attagctact
     7261 ttttgagctt gctctttggt agcttctact gcttgttcaa cttttttaga aacagcctta
     7321 ccagctgcgc ttgctgactg ttctgcacgc ttcacgactt tttttgtctc atctacaacc
     7381 ttagtcacag tacttgaaaa ggcacctgcg cgacggaggc catttcgtaa ttgtttttta
     7441 cgattgagtt tctttgacat gataaaatcc tttcaataaa aaatccctgc tctgacaagg
     7501 atttaacata aacattctat caagatttta gtgaaaaatc aagaatcttt ctcgtttaat
     7561 aatttcgctc accaaacaag ccttctggca aatcatggaa tcccttgcct actttgaagt
     7621 tttcaaactt accaagcaag aactgataag catccaagcg actctcgtag cgaatcatgg
     7681 catctttggc acgctcgtcc tggtcttctt cgtaaacttt ttgactttcc ttgtgcgcca
     7741 tgtcgttaat catgatttgg gtattgaccc aagcttcaaa ttccttcata aattcttgtt
     7801 cgtaactcat ttttctcctt attctaatcc acgaaaatag tccgtatcaa tctcacggta
     7861 gggctggata tcctgaacat actccaacac tccttggaat tctccgtctt catcgtgtac
     7921 tgcagcatag gtgatgtgga caaacttacc tcgcgactca gacttgaacc acatttcata
     7981 cttgtctttg cttccctcac gaagcctctt catgatagtt ttgaccttgt ccaagtactt
     8041 aggcggatgg cagagttcga cattgcgccc gacttgagac ggcgtccgtt tgaaaatcat
     8101 ctcatcagct ggcgtattgt cattgtaata ctggaaaata tcttctttat tgacaaaggt
     8161 aatctccata gggagatgat tgaggatgag attggcctgc tcgactgaaa gatagccatt
     8221 accaaaagcc tgttgactat ggcggtccag cacagcttcc ttttccttag gggtaaaggt
     8281 aatggtaaaa tggccttctg gcgtatctat gacttgttga acttgacctt ctgccgtatc
     8341 tagctgtaca ggctcctctg caatcttttc ctcaataaag ctctgtcgtt ctggcaccca
     8401 tttctctgac ggacggatga tggcatagcc ataggcatcg ctctcctccg caatctgaag
     8461 ccagtcatcc tgagtaaaag actcaaggag aatcatgagg aggatggact cttccttgaa
     8521 aatcatactt tcaaactctg tcgcaaaagc ttcaaaagct tcctttacac tgctaattga
     8581 cacttctggt agtgacttga ctgtcgttag agctgtttga aagagttccc taatctgatc
     8641 atccactccc cacataactt tgggaggtga atcgtgtcca tagcgctcca tgataggaaa
     8701 gaagagttct tccttacgtt ggtaatggat gtcaaattgc cccacaagcc ccatctgacg
     8761 caccaagccc ttgcgcatct ccgcaagcat ttcctcgtct tccatcaact cataggtatc
     8821 taacaatcta cgaatgcgaa tcaaagctgc acggagggcc aaattttctt ccttaaagac
     8881 acgaactggg tgcccagggt gttcggtatc taaaacttcg acacctttga tagcattttt
     8941 aaaaagattg gcatggacat cacagagttc cataacatct tcaaaagtga cgcccgaatc
     9001 cgagttcatc agctcgtgct ccataaggga aatctcgatg gctgacacgc ccgtaaaggt
     9061 cgcatcaaag cgatcttgaa ccgactcagg agaggcgcca ttgtgcaatt ctaacaaaat
     9121 atcccgtagg atatgaatcc attcatctgt cattagtcta atccaatcac ttcgtagcca
     9181 ttcgcttcca gtgtgcgtac aatcttgtcc ataggagttc ctgttagctt agaaccctgt
     9241 ttaagtgata ctttacgacc aactgtattg cgcattaagg gattggcaag gggtttaaaa
     9301 cccaactcca ctagaatttc caagacttct ggatgcttgt ccaccacttc tgcaacagga
     9361 attgacacat cgatgatatt gtccatgacg acctccattg tatgttctaa tactcaatga
     9421 aaatcaaaga gcaaactagg aagctagccg caggttgctc aaaacagtgt tttgaggttg
     9481 tggatagaac tgacgaagtc agtaaccata cctacagcaa ggtgaagctg acgtggtttg
     9541 aagagatttt cgaagagtat aaaatgattt tactgcttat attataccat atggagagag
     9601 attaaaaaac tagcagtgga gttcctgcta gttttctgcg acttggatta ccatctagat
     9661 aagtttaaag aaccaatcca atatcttgta aaacagcaat tgaactgcaa aagaaatgat
     9721 catccaaaag aatttcacaa tcccaataat cggtttgata aaaagaatag caagaattgt
     9781 ccagaaaaat ttcattctct ctcctctggc ttaatgagcc accgagccgt atccattagc
     9841 ttatctgcaa taaagagttt tcccagacca acaacgacat ggtcatcttt ctttatcgtt
     9901 ttcatcactt ttacaccttg cacggtcaaa aagtaattac cataaatttt agcaaaagct
     9961 ttgataggat tcatattatt ctcctttgat gatttcagcc tcttttcgga ttgtttcaac
    10021 atcttcttga tattgaactt cactatagtt gactagcttg gataattctt tctgcaagct
    10081 ttcccccatt ggtttcatag ttgcaaaggt taaaccacct gaaatgatac cacccaagat
    10141 aggaataaat ttccccattc ctttggccaa ccctcccttg gtaagattca caccaaatat
    10201 ttttaagact tttttcaaaa tagggtacca aagcgtcttt gttaaagctt tattaggcac
    10261 tgttttcatt acctgtttgg caattgttat accaccagca cgtagcaaac aaagcagcgg
    10321 ttccattcac ccctaacatt acgcctagat aaagcaagag ggtattttga gcatcttcac
    10381 tcaactcctc acgtgaagcc caaagatcct cataaccata aatataacct aattcttggg
    10441 ccaatttcag agagaaacca taaaattgag ccacataagc tggaatggta attgccatag
    10501 caagccctcc aggtaatcct gccaaaacag aagtcccact cgctaataaa acattatccc
    10561 taatacaggc attagccact cgatctaaga tttcttgaga taagagagac gttggacctt
    10621 gttccaataa ggtaggaatg tcctgtggac ccaattcttt ggaaaactta tccactaaaa
    10681 atttcgaacg atcaacctta acaactggta gttttaccac ttgttgtaat acttgcatag
    10741 ctaagtcttg ttcagccata tacaaactcc ttatttcttt tttgcacctt atcatattat
    10801 atttcctaca aaaaaagcat tttctaatta gataacatta aaaaatacag aacccctttt
    10861 ttatagtaaa ataaaacaag aacaggacaa atcgatcagg acagtcaaat cgatttctaa
    10921 caatgtttta gaagtagagg cgtactattc tagtttcaat atattttaaa agaatatttt
    10981 tccatttcaa attcaaccta ttttcctcca ccaaaaaagg gctctataat atttgtagtg
    11041 ggtaaattcc ctatggatat tatggagcct atttttgtgt agaaaaaaag tcccatatga
    11101 cctataatga aaagcgacaa aacaactcat tagaaagaat catatggaac aattacattt
    11161 tatcacaaaa ctgctcgata ttaaagaccc aaacatcaag attctagata tcatcaataa
    11221 agatacac
//
LOCUS       DAVAZT010000062        11086 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVAZT010000062 DAVAZT010000000
VERSION     DAVAZT010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11086
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.062"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(6..890)
                     /locus_tag="VQT45_001798"
     CDS             complement(6..890)
                     /locus_tag="VQT45_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HET2360072.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDMIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(894..1280)
                     /locus_tag="VQT45_001799"
     CDS             complement(894..1280)
                     /locus_tag="VQT45_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HET2360073.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLISLMLEEQILTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            complement(1273..2616)
                     /locus_tag="VQT45_001800"
     CDS             complement(1273..2616)
                     /locus_tag="VQT45_001800"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HET2360074.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYEVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEGLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            complement(2698..3582)
                     /locus_tag="VQT45_001801"
     CDS             complement(2698..3582)
                     /locus_tag="VQT45_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2360075.1"
                     /translation="MIQVRNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHIEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            complement(3594..4211)
                     /gene="cysE"
                     /locus_tag="VQT45_001802"
     CDS             complement(3594..4211)
                     /gene="cysE"
                     /locus_tag="VQT45_001802"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HET2360076.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFIW
                     KHGFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            complement(4227..6440)
                     /gene="pnp"
                     /locus_tag="VQT45_001803"
     CDS             complement(4227..6440)
                     /gene="pnp"
                     /locus_tag="VQT45_001803"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HET2360077.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDDQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRLELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            complement(7125..7991)
                     /gene="metF"
                     /locus_tag="VQT45_001804"
     CDS             complement(7125..7991)
                     /gene="metF"
                     /locus_tag="VQT45_001804"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HET2360078.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            complement(8055..10304)
                     /gene="metE"
                     /locus_tag="VQT45_001805"
     CDS             complement(8055..10304)
                     /gene="metE"
                     /locus_tag="VQT45_001805"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HET2360079.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVASDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            complement(10565..10831)
                     /locus_tag="VQT45_001806"
     CDS             complement(10565..10831)
                     /locus_tag="VQT45_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2360080.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGVSQPVIARMETGESSLQLDTVLKVLTSLGKTLAVVPLEQGKS"
     gene            complement(10915..11086)
                     /locus_tag="VQT45_001807"
                     /pseudo
     CDS             complement(10915..11086)
                     /locus_tag="VQT45_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT         3095 a         2540 c         2194 g         3257 t
ORIGIN      
        1 cttctttaca aaccaactat agttgacaaa gaacctaaaa tcaattgata acacaaggtc
       61 aggtcggtca actctttcaa ctgaagccct gtcaactctt cccatttatc aatcttgtat
      121 tggagagaat tgcggtgcag atagagttgc tgggctgttt tagtgagaac agcactattt
      181 tcccaaagag agagaatgat ttcctgaatc tgatcttgat ccaaaatcat ctggtgtaga
      241 cattctttaa ttggcttcaa gtccacgagt ctttctccca tactccaaag atagagctga
      301 gaaaaagtat gaacaccttg gtgaccctga cgccaccatg tcttgaacaa atcccgctca
      361 gctttgatta agtctgatag ggcttgatgt cctgtctgag accaaacctg acccaacatg
      421 atagaaagac gaagtccaaa gtcatactca actgcttcaa tcatatcact taaaatatct
      481 cttacagaag tgtatttgtc ttgttgaagc acgaaaacat aatcctgagc tccgacctgt
      541 aacactgtct gacaattcgg aaaaagagtc cgcatcatat ctagccaaga agccagattt
      601 tcctgctgaa aataagaaag atggcaataa accaactgaa tctttttaaa aacttgcggt
      661 gcctgtccct tgccttcaac cagataggaa taccaagggt ttagcgaacg agcctgctcc
      721 tgctgggtca aaagggcaac caactgcttt tcacgctcgc tgagcccagc ttcctccagc
      781 aaaatccact gctgagaagc taaaggaagc gtgagatagc cctctttctc tactggttgg
      841 tctgaaatcc gagcctcagg aaaccagtct tgtagttctt ttgccctcat gttctagccc
      901 tccacttttt ggatgcacca tgaaaccaaa ctctcaagac gttccagatt ctcagtcata
      961 tggagatagc ccataactgc ttcaaatccc gtggacatac gataagtcac gacatctgca
     1021 tttttagcct ttgtgtgact attggtattg cggccacgtt tgtagatttc ttcttctttt
     1081 tccgttagga tctgctcctc caacatgaga gaaatcaggc gagcttgagc cttggctgac
     1141 acgtacttgg tcgcctcttg gtggagttta ttgggcttgg tcataccttt gaggatgagg
     1201 tggcggcgaa tatacataga atacaccgca tctccctcaa aggctagcgc aatcccgtta
     1261 atgagattga catcaatcac gtgtccacct cactccatcc ttggtatcaa ggagcttaat
     1321 tccttgagta accaattggt cacggatttg gtctgctgtc gcaaagtcac gattggcacg
     1381 cgcctcttgg cgtttttgaa tcaagtcttc aatctctgca tccaaaactt cctcaacaaa
     1441 gacaattcca aaaatttcta acatatctgc aagagcttgc ttgacacttg catcatagtt
     1501 ccctgagttg atccatttgg ccatttcaaa gacaactgtg ataccgttgg cagcattaaa
     1561 atcttcatcc atagctgcta caaacttatc tttaaagttt tgtaactctt gggcatccac
     1621 gtttcctgta aatggttgtt cgtaagtatt cttcagatac ttgagattgg tctcggcatc
     1681 gcgaactgcc ttttccgtga agttgatagg cttacggtag tgctgggtcg caaagaagaa
     1741 acgaagtact tgcccatcaa gagttttaag ggcatcgtgt accgtaatga agttacccaa
     1801 ggacttagac attttgacat tgtcgatatt gacaaagcca ttgtgcatcc agtagttagc
     1861 aaaagccttg cctgttttag cttcagattg ggcaatttca ttggtgtggt gtggaaactc
     1921 taggtcagct ccaccaccgt gaatatcaat ggtatcacct aaaatctctg tcgacatgac
     1981 tgaacactca atatgccaac ccggacgtcc aggtccccaa ggactatccc aagaaatctc
     2041 acctggtttg gaagatttcc atagagcaaa gtctacagga ttttccttac gagccgtttc
     2101 ttcatcggta cgacctgaag cacctagctc caaatcttcc aaggttttat tagccaattt
     2161 agcatagttg tgggattttt ctacacggaa atagacatcc ccttgactct cataggcaaa
     2221 gcctttctcg atcaagcctt ccacaaaacg gatgatgtct gccataaact ccactacacg
     2281 cggatggcga gtcgcaggtt tcacgcccaa ggccgtcaca tcctcacgaa aggcagcgat
     2341 gtacttatcc gcaacctcct gaggcgtgat gccttcttcc ctggcacggt tgataatctt
     2401 atcatccaca tccgtaaaat tggaaatata ggcaacctcg tacccacgat actcaaaata
     2461 gcgacgaatg gtatcaaaag ctaccgttga acgagcattc cctacatgaa tatagttgta
     2521 caccgttggc ccacaaacat acatcttgat cttgccgtcc tcaatcggga caaattctcg
     2581 caaatcacga gacatggtgt catagatttt aatcataaat cataatcaag aaagctgaaa
     2641 tccaagaaca attagtttca tcactaaaag ttcaagtaaa tttcagtccg aatatctcta
     2701 cacttcggaa tcccttgctc ctttctcatt cagataaacc acctgagtct gtttgacaaa
     2761 gccaattttt tcatacaaac gtttggcacc tacattgcta tcttccactg caatctgaaa
     2821 ttccttgtca ttttgctcaa ttagttggtt gacgagggat tttgctaagt agcttccata
     2881 gcctttccca cgttcaggtt ccgatattgc taaaccgtag aagtaattcg tattagtcga
     2941 taaatctacc gtgcaagtcc caataacctg accgtctttt aacaaaatat atagtcggct
     3001 ttctggatcc ttcagagctt cagcgacata tctatccaca acttctctcg attcatgttc
     3061 ctctgaaaat gcctgaaatt ttaattgact aatttgatcc tgatacgaac tatctgctaa
     3121 caaaacttca atatgggaaa catttgctaa cggataaggt cttctatcct tacctaacca
     3181 agtttctgtc tcttcatcct cgattagtcc ccagttactg gcaaagtcag gatgattctc
     3241 taaaaaaata cgttctgtct gaaaagtgac tgatcgaatg gggaaagaag ctgtttctct
     3301 ctcaaaacta gtaaacaatg cacgcgcaat cccctgacgg cgatgacctg gatgaaccag
     3361 tatcgtcact tctacatctt ggtcatctgc atagacagtt aataaaccaa caagttcgcc
     3421 tttttcataa taaaggaaaa aggcgggcat gtttgggtca aaattaagca tgttagagag
     3481 atagggatcg cgataggtac cgtcatagtt ttggcaacag ttaattactt ttttcgcctc
     3541 agatagctcc tcttggctta acttgtttct tacttgaatc atataggtat cctctacaaa
     3601 ccagacgatc tgtgactggc atctttagcc tgctcgagtt tattgacata atactctcgt
     3661 ttttcttcga cttcgtgaat gacaggctca tctttcttac catgaagacg gacaatcttg
     3721 gccggaatac cgacaaccgt cacatcacta ggtacatctg ctacgacaac tgctgcagca
     3781 ccgaccttgg cattttcacc aatttccaca ggtccgataa cttgggcatg ggctgatatg
     3841 agggctccct ttcgtacagt cggatggcgt ttgccacagt ctttccctgt tcccccaaga
     3901 gtcactccgt gatagagaag aacgcctttt tcaacaatcg ctgtctctcc aatcaccaga
     3961 ccagaaccat ggtcaataaa gacacctgaa tcaatctggg ctcctggatg aatctcaatc
     4021 tgagtccaaa agcgccaaaa ctgactgtgc atacgagcta agagtttgaa gccgtgcttc
     4081 cagataaaat gcgagagacg gtgggccgcc aaggccttga cacctggata agtcagcaaa
     4141 acctccaaag tggtgcgggc cgctggatca ttttctttta cgatatcaat ggtttcgcgc
     4201 caccacccca tacatttctc cttttcttat tctgaatctt ttggtgtttc tgtaaattct
     4261 ttcttaggtt tgtgatcctt gtgatgacgt gggcggtgag gacgctcaga cttttcacct
     4321 ttttcatcat gctcaggttt tggcggacga ggtagaagag ccttcataga ggcatcgata
     4381 cggccttttt catcaatctt gataacctta acatcaactt catccccgat ttctaccaaa
     4441 tcctctacac gattggtacg agtccaagcc atctcagaga tatgaacaag ggcatctgtc
     4501 ttatcaaaga ggttaacaaa ggcaccaaat ttctcgatac gaacgacttt agcacggtaa
     4561 acttcatcca ctttggcttc acgaaccaaa ccagcaataa tttctttggc acggttaata
     4621 gcatcttggt cactagagta gatagacaca tttccttctt cgtctatatc aatcttaaca
     4681 cctgtttcag cgataatctt gtcgatggtt tctccaccct taccgatgac aatcttaatc
     4741 ttgtccacat caatcttgat cgtatcaatt ttcggagcag ttggagccaa ttctagacga
     4801 acttctggaa tggttgcttc aatgacatca aggatttcaa aacgcgcttt cttggcttga
     4861 gcaagagcct ccgtcaagat ttctgcagta atcccttgaa tcttgatatc catttgaagg
     4921 gctgtaatcc catcacgagt acctgcaacc ttgaagtcca tatctccaaa gtgatcttcc
     4981 aaaccttgga tatctgtcaa tactgtgtag ttatttccat ctgagataag tcccatagca
     5041 ataccagcta ctggcgcctt gattggcaca ccaccagcca taagggcaag agttcccgca
     5101 cagatagaag cttgagatga agaaccgttt gattccaaaa cttctgctac tagacggata
     5161 gcgtatggga attcttccaa gcttggcaag acttgagcaa gagcacgctc accaagggca
     5221 ccgtgaccga tttcacgacg acctggcgca ccgtaacgac ctgtttcccc tacagaatat
     5281 tgagggaagt tatagtggtg cataaagcgt ttcttgtact ctggatccaa accatcaatg
     5341 atttgagttt ctcccatcgg agccaaggtc aagactgaaa gagcttgagt ttgcccacga
     5401 gtaaagagac ctgaaccatg tacacgagga aggaagtcaa caaccgcatc caaaggacgg
     5461 atttcatcga ccttacgacc atcaggacgc accttgtctt ctgtaattaa acgtcgcact
     5521 tctgcgtgtt ccatttgttc caagatttca gccacatcac gcataatacg gtcaaattct
     5581 tcgtggtccg catatttttc ttcgtaaacg gcagtcactt ggtctttcac tgcttgagtt
     5641 gcagcttcac gggccaattt ctcttctact tgaactgcct tttggaggtc actgttgtag
     5701 gctgcaatga tttcagcttg caattcagca tccacgtgaa gcaattccac ttctgctttt
     5761 tctttaccga cagcagcaac gatttcttct tggaaggcaa tcaattcttt gacagcttcg
     5821 tgccctttaa gaagcgcttc caacatgatt tcttctgaca attctttggc accagactct
     5881 accatgttga tagcgtgctt agttccagct actgtcaatt caagaagaga ttgctctgct
     5941 tgttcttgac ttgggttgat gatgatttgg tcatctacat atcccacttg taccccagca
     6001 attggtccgt caaatggaat atctgaaata gacagtgcca aagatgaacc aaacatagca
     6061 gccattggtg cagatgcatt ttcatcataa gaaagcactg tattgatgac ttggacttca
     6121 ttacggaaac cttccgcaaa cataggacga atcggacggt caatcaaacg cgctgtcaag
     6181 gtcgcatctg ttgaaggacg tccttcacgt ttcataaagc caccaggaaa cttcccagcc
     6241 gcatacattt tttcttcgta gttgacttgg agtgggaaaa aatccccagt tgccattttc
     6301 ttagacataa cggcagcagt caagacagtt gactcaccgt aacgtacgac aacagagcca
     6361 tttgcttgct tagcaacctg accagtctct acaattaact cacgacccgc aaaagtcgtt
     6421 tgaaacactt gttttgccat tttaatcccc tttggattga tgaaattata cgccttgcct
     6481 acaaagatca agataccaag gacgtcaaaa gcaaagtaaa aataggaaac tgacgaagtc
     6541 ttcgatgaag acaagacagt ttatcttttt tacacagctt ttcggccgtg ttcaattaca
     6601 caagatattt tggacggttc ggcttgccga acatttctgt agaaaaatag gaaggtgacg
     6661 tcgcactcga cgagtgctag gaagcttatc ttttttccta agaaatgaga ccaaaattca
     6721 agtcatcaag ataccaagcc gtcaagcaac tcaaaggaag ataggaaatc gaacgacgga
     6781 gcgactgctc ctaggcagat ttatcttttt ccacagagtt gtaggcgtgt tcagttttca
     6841 agatacatca ttagaaaggt ttaatattaa agtatctaaa cctttcacgc taatcgctat
     6901 cgggcgatta gctaaatgct ttactaactc tttcgtcaaa taacatcgat ttgactcact
     6961 cgtgtcgtta aatcttacag tttaaatgca ttgtattatt taataccttc atctttgtat
     7021 caagtacgta cagaatctat tttatcatat ttttcttaaa aagtgaggtc tttaccatta
     7081 aaaaggaacc attcccctca cctgagaaga atggtttgct tttattatcc tagagactgg
     7141 tgattaaaca aggcatgggt tgcttgatgg atgtattttg ctgtatcagc attattcatc
     7201 gtatagagat gcacaccggc aacatcctga gttaccaagt ccacgatttg gtccactgca
     7261 taggcaagtc ctgctgctct gagcgactca gggtcatgct catacttgtc taagatggct
     7321 ttaaatttgc gtggaagatg gatattctca caagtcttca agagtcggag agcctgattt
     7381 cgattcagaa ttggcataat tcctgcatga ataggaacat caatcccagc caagatacac
     7441 ttgtcctgaa aatcatagaa gcgctcattg tcaaagaaga gctgagttac gaggctcgaa
     7501 cagcctgcat ccactttctt cttaagattt tgaatatctg aaatctgatt tggcgaatct
     7561 ggatgccctt ctggatagca agctccaata atatcaaagt gaggggcttg ttccttgata
     7621 aactcaatca agtcggttgc atagcggaaa tccttttgtg gttctacgtc tggaataata
     7681 tccccacgaa gagccaagat tttctgaacc ccaactttgt ccaagtcagc aatagtttca
     7741 gcaaccttgt ccttagttag ataaatagct ggcaagtggg caatggtcgg aatcgccaag
     7801 tcattttgga taaagtcagc caaacgaacc gtcgtttcct tgatattaaa tttattattg
     7861 ctggcagtta cactgataaa atggggagcc aactcctgca tatcctgcaa ggctgaaata
     7921 atgttaccat tacccacggc tgggtttgga gggaacactt caaatgagag tgacggtgtt
     7981 tggcgtgaca tatgtaataa ccttttctag ttgatttctt tttgaacaac cactgtatgg
     8041 agagaaatcc aatcttacaa tttctcacgc gcagctttag ctgcttcaac aaggcggatc
     8101 aagctttctt ttgtttctgg gataccacgt gttttcaaac cacagtcagg gttgatccaa
     8161 actttcttgc ttggcacttt agcaaggatg gcttcgattg tgttgtcgat ttcgccttca
     8221 tttggtacac gaggtgagtg gatatcgtaa accccaggtc ccacttctgt ttggaagttt
     8281 ttcgctttga gttcgtccaa gatttcaagg tttgaacggc tggcttcaaa ggaaataacg
     8341 tctgcatcca tgttatcgat agctgggatg atatctgtaa attctgagta acacatgtga
     8401 gtgtggattt gtgtgtctga cgctactgtt gagtgtacca agcggaaggc aggaattgcc
     8461 cagtcaaggt aatcttcgta ccagtcacta cgacggagtg gcaatttttc acgaagagca
     8521 gcctcatcaa tttggatgat tttcacacca gcagcttcaa ggtcaagcac ttcatccttg
     8581 atagcaaggg cgatttgaag agtagaatcc ttgatagaga tgtcttcacg tgggaatgac
     8641 cagttaagga tggtaacagg tccagtcaac atacctttaa caggtttgtt tgtacgactt
     8701 tgtgcatagc tagaccattt aacagtgata gggttaagac gagtgacatc accccagatg
     8761 attggtggtt ttaccccacg cataccgtat gattgtaccc atccattttt agagaagagg
     8821 tatcctgaca agttttgacc gaagtactca accatgtcat tacgctcaaa ttcaccgtga
     8881 acaaggacat caaagtcaat atcttcttgc cacttgatcc attcgtcaat cgtttcagca
     8941 aggaaagcat cgtactcttt ttgagacaat tcacctttac ggtaagccaa acgtttggca
     9001 cgaacttctt ttgtttgagg gaatgaacca atcgttgttg ttggaagagc tggaagtttg
     9061 aaagcttctt cttggatagc ttcacgttct gcaaaggctg gcaaacgagt gtagtctgcg
     9121 tctgtcaagc cagcgatacg cgcacgaagt tcagcatttt caccaacacg ctcagtcgca
     9181 aagagttctt tgttggctgc aagagcttct gaaccttgac cattgcggat agcatccaag
     9241 tcacggattt catccaattt ttcaactgca aaggcaaagt ggttcaagag tgctggttca
     9301 aattcttcat tagcagttgt aaatggcaca tgaagaagtg agcaagagct tgtcaaaacg
     9361 atgttttcag ctggaatttg ctcaagaaca gccaagctct tttcgtagtt gttgcgccag
     9421 atgtttttac cattgacaat acctacatag agagtcttgt cagctgggaa gccaccttta
     9481 acgagttcaa gagttttctt accttcaaca aagtcaagac cgatagcatc tactggtaag
     9541 tttacaaggt cagcgtatac gtcacgaaca tcaccgaaat aagtttgaag caagacttca
     9601 agaccttttt tgtcagccaa gagtttgttg taaaggttca agaagagagc tttttcttca
     9661 gctgtcaagt cttttacaag agccgcttca tccaattgga tgcgagtcgc accaagttca
     9721 gccaatttag caaaaacttc ttggtaagca gccactaagc tatctacgaa gtcgtctgct
     9781 ttcacgcctt cttcaaagtc tgacaattga aggaaagtga agggacctac aagaacagga
     9841 cgagtgttca atccaagttc tttggcttct tggaactcat cgaaaatctt gtgaccagcc
     9901 aattttactt gagtgtcttt ttcaaattta ggaacgatgt agtggtagtt agtgttgaac
     9961 catttcttca ttggaagggc gcgaacgtcc cctttttctc cctggtaacc acgtcccaaa
    10021 gcgaagtagc gctcaaggtc agacaagtcc aagttttgaa cggatgcagg caccacgttg
    10081 aaaaggaaag ccgcatctag gaagttatca tagtgagaaa agtcatttga tggaatttca
    10141 gtgatgcctt tttctttgac aatgttccag tgtttagcac gcaagtcttt tgctgctgct
    10201 aaaagttctt cttctgagat ttcttttcta aagtattttt cagttgtaaa ttttaattca
    10261 cggaattcgc ccaaacgagg gaaaccgatg attgtagttg acatgatgtg tcctccaaaa
    10321 tttgttgttg aaactatctt aacagaaaag aaagcgtctg tataattgta aaaaattagg
    10381 gtttgatata gtttgaaact atatatctgt ttcggacaaa agaaaaagac ttgaagcaaa
    10441 cgtctcaaat cctttgtaat tcttacttta cagctatatt ccaattagaa tactaaaaca
    10501 tgttattagt aattcttata agtgactatg acctgttatt agaaaagact ataactgatt
    10561 ctagtcaact tttcccctgt tcaagtggaa cgactgctag tgtctttcct agactggtta
    10621 gaacttttaa gaccgtatcc aactgaagac tgctctctcc tgtttccatc ctagctatga
    10681 caggttgact cactccactg acttcttcca gctttttctg actgattcct tgttcatacc
    10741 tagcctcaat caactcgctc atgatagcca ctcgcatatc actttcaagg atttcctcct
    10801 tgctaaagag ctcagatgga catccttcca attactccca atagcactat tcttcatcac
    10861 ttaaccctct ttcttttacg tctatgtatt tttaaaagaa tgagcgaatt atgattcgat
    10921 agattgacca gcaggtttaa agttggtgct agcctgtttc ttaagcgctt ttccttttct
    10981 agggtaaagc agatcctgct tgcttaaccc caattttcca cgatgaatcc aatagtaaat
    11041 ggttgaaatt cccacgttaa cccctttagc catcaccatc atttca
//
LOCUS       DAVAZT010000063        10989 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVAZT010000063 DAVAZT010000000
VERSION     DAVAZT010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10989
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.063"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            136..2316
                     /locus_tag="VQT45_001808"
     CDS             136..2316
                     /locus_tag="VQT45_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET2360081.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDTSQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKNLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            2368..3183
                     /locus_tag="VQT45_001809"
     CDS             2368..3183
                     /locus_tag="VQT45_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET2360082.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETLVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            3323..4666
                     /locus_tag="VQT45_001810"
     CDS             3323..4666
                     /locus_tag="VQT45_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2360083.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLEIVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            5043..6233
                     /locus_tag="VQT45_001811"
     CDS             5043..6233
                     /locus_tag="VQT45_001811"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HET2360084.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            6786..7721
                     /locus_tag="VQT45_001812"
     CDS             6786..7721
                     /locus_tag="VQT45_001812"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HET2360085.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            7755..8792
                     /locus_tag="VQT45_001813"
     CDS             7755..8792
                     /locus_tag="VQT45_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET2360086.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNSSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            8965..9570
                     /locus_tag="VQT45_001814"
     CDS             8965..9570
                     /locus_tag="VQT45_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HET2360087.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            9726..10256
                     /locus_tag="VQT45_001815"
     CDS             9726..10256
                     /locus_tag="VQT45_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HET2360088.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            10277..>10989
                     /gene="rlmN"
                     /locus_tag="VQT45_001816"
     CDS             10277..>10989
                     /gene="rlmN"
                     /locus_tag="VQT45_001816"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HET2360089.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQGIVQESADGTVKYLFELPDGMLIETVLMCQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERISHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSISGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFP"
BASE COUNT         3341 a         2017 c         2395 g         3236 t
ORIGIN      
        1 tagaaatttt ttagaaaaaa gtgtaatttt tttataaaag cctttacaaa aaaaattaaa
       61 gtggtataat taaatcatag aaggtgcaaa cgttttcgta aaacgtttgc ctaaataaaa
      121 ataaaggaga tttgaatgat gaaagataca ttcaaaaatg tcttgtcttt cgaattttgg
      181 caaaaattcg gtaaggcttt gatggtagtt atcgcggtta tgccggctgc tggtttgatg
      241 atttcaatcg gtaagtctat cgtgatgatt aacccaacct ttacaccact tgtcatcaca
      301 ggtggaattc ttgagcaaat cggttggggg gttatcggta accttcacat tttgtttgcc
      361 ctagccattg gaggaagctg ggctaaagaa cgtgctggtg gtgctttcgc cgctggtctt
      421 gccttcatct tgattaaccg tatcactggt acaatttttg gtgtatcagg cgatatgttg
      481 aaaaatccag atgctatggt aactactttc tttggtggtt caatcaaagt tgctgattac
      541 tttatcagtg ttcttgaagc tccagccttg aacatggggg tattcgtagg gattatctca
      601 ggttttgtag gggcaactgc ttacaacaaa tactacaact tccgtaaact tcctgatgca
      661 ctttcattct tcaacgggaa acgtttcgta ccatttgtag ttattcttcg ttcagcaatc
      721 gctgcaattc tacttgctgc tttctggcca gtagttcaaa caggtatcaa taacttcggt
      781 atctggattg ccaactcaca agaaactgct ccaattcttg caccattctt gtatggtact
      841 ttggaacgtt tgctcttgcc atttggtctt caccacatgt tgactatccc aatgaactac
      901 acagctcttg gtggtactta tgacatttta actggtgcag ctaaaggtac tcaagtattc
      961 ggtcaagacc cactatggct tgcatgggta acagaccttg taaaccttaa aggtactgat
     1021 actagtcaat atcaacactt gttagataca gtacatccag ctcgtttcaa agttggacaa
     1081 atgatcggtt cattcggtat cttgatgggt gtgattgttg ctatctaccg taatgttgat
     1141 gctgacaaga aacataaata caaaggtatg atgattgcaa cagctcttgc aacattcttg
     1201 acaggggtta ctgaaccaat cgaatacatg ttcatgttca tcgcaacacc tatgtatctt
     1261 gtttactcac ttgttcaagg tgctgccttc gctatggctg acgtcgtaaa cctacgtatg
     1321 cactcattcg gttcaatcga gttcttgact cgtacaccta ttgcaatcag tgctggtatt
     1381 ggtatggata tcgttaactt cgtttgggta actgttctct ttgctgtaat catgtacttt
     1441 atcgcaaact tcatgattca aaaattcaac tacgcaactc cagggcgcaa cggaaactac
     1501 gaaactgctg aaggttcaga agaaaccagc agcgaagtga aagttgcagc aggctctcaa
     1561 gctgtaaaca ttatcaacct tcttggtgga cgtgtaaaca tcgttgatgt tgatgcatgt
     1621 atgactcgtc ttcgtgtaac tgttaaagat gcagataaag taggaaatgc agagcaatgg
     1681 aaagcagaag gagctatggg tcttgtgatg aaaggacaag gggttcaagc tatctacggt
     1741 ccaaaagctg acattttgaa atctgatatc caagatatcc ttgattcagg tgaaatcatt
     1801 cctgaaactc ttccaagcca aatgactgaa gcacaacaaa acactgttca cttcaaaaat
     1861 cttactgagg aagtttactc agtagcagac ggtcaagttg ttggtttgga acaagtaaag
     1921 gatccagtat ttgctcaaaa aatgatgggt gatggatttg cagtagaacc tgcaaatgga
     1981 aacattgtat ctccagtttc aggtactgtg tcaagcatct tcccaacaaa acatgctttt
     2041 ggtattgtga cggaagcagg tcttgaagta ttggttcaca ttggtttgga cacagtaagt
     2101 cttgaaggta aaccatttac agttcatgtt gctgaaggac aaaaagttgc agcaggagat
     2161 ctccttgtca cagctgactt ggatgctatc cgtgcagcag gacgtgaaac ttcaacagta
     2221 gttgtcttca caaatggtga tgcaattaaa tcagttaaat tagaaaaaac aggttctctt
     2281 gcagctaaaa cagcagttgc taaagtagaa ttgtaatata cttgaggttg gaagctgtat
     2341 tccaacctct tattttggga gaaaagaatg aaatttttaa cactcaatac tcacagttgg
     2401 atggagaaag aagcagagga aaaattccag attttgcttg aagatattct tgaaaaggac
     2461 tatgatttga tttgtttcca agaaatcaat caggagatga cctcgtcaga ggtggaggtt
     2521 aatgaccttt atcaagcttt gccagcagct gagcctattc accaagacca ttatgttaga
     2581 ctcttggttg aaaagttgtt agagcaaggg aaaaattact actggacctg ggcttataac
     2641 catatcggct atgaccgcta ccacgaaggt gtggctatct tgtctaaaac acctattgaa
     2701 gccagagaaa ttttggtttc agatgtggat gatccaacag actatcatac tcgccgtgtt
     2761 gccctagctg aaactttagt cgatggcaag gagctagcag ttgccagtgt tcatctctct
     2821 tggtgggata aaggtttcca agaagaatgg gcacgatttg aggctgtctt gaaaaaattg
     2881 aacaagccac ttttactagc tggagatttt aacaacccag caggtcagga aggttaccaa
     2941 gctattttag ctagtccatt aggcttacaa gacgcatttg aagttgctca agagaaaagt
     3001 ggtagctata ctgttccgcc tgaaattgat ggctggaaag ggaacactga accccttcga
     3061 atcgattatg tctttactac caaagagtta gcggtggaaa atttacatgt cgtatttgat
     3121 ggtaacaaga gtccacaagt gagtgatcac tatggcttga atgctatgtt aaactggaaa
     3181 taataactga aaagaggttg gaactataaa attccagcct tttcttacta gagaagctac
     3241 tggaaatagc ctaaataagt gagactactg taatggaata aaatatggta taattgataa
     3301 gatagataga atcgaggatg ttatgtcatt tacgaaattt caatttaaaa actatattag
     3361 agaagccttg aaggagttaa aatttacaac tccaacagag gtgcaagata agttgattcc
     3421 tattgttttg gcaggtcgtg acctagtagg agaatcaaaa acaggttcag gtaagactca
     3481 tactttcttg ttaccgattt tccagcaatt agatgaagct agcgatagtg tacaagcagt
     3541 gattactgca ccgagtcgtg agttggctac tcaaatttac caagtagcgc gtcagatttc
     3601 agctcactca gatgtcgaag ttcgtgtggt taattatgtg ggtggtacgg ataaggctcg
     3661 ccagattgag aaattggcaa gcaatcagcc tcatattgtt attggaacac caggccgtat
     3721 ctacgacttg gttaaatctg gtgatttagc tattcataaa gccaagacat ttgttgttga
     3781 tgaagcagat atgaccttgg atatgggatt cttggaaatt gttgataaga ttgctggcag
     3841 tcttccaaaa gacttgcaat tcatggtctt ctcagcgact atcccacaaa aactgcaacc
     3901 attcttgaaa aaatacttat caaatcctgt tatggagaaa attaagacta aaacggttat
     3961 ttctgacacc attgataatt ggttgatttc gaccaaggga catgataaga atgctcaaat
     4021 ttaccaattg actcagttga tgcagccgta tttggcaatg atttttgtta acactaaaac
     4081 gcgtgctgat gaattgcatt catatctgac tgctcaaggc ttgaaggttg caaaaatcca
     4141 tggagatatt gcccctcgtg aacgcaagcg aatcatgaat caggtgcaaa atctggattt
     4201 tgagtatatt gtcgcaacag atttagcagc gcgtgggatt gacattgaag gtgtcagcca
     4261 tgtcatcaat gatgccattc cgcaagactt atcttttttt gttcaccgtg ttggtcgtac
     4321 tggacgaaat ggcctaccag gtacagctat taccctttat cagccaagtg atgactcgga
     4381 tatccgtgag ttggagaaat tgggaatcaa gtttagtcct aagatggtca aagatgggga
     4441 atttcaagat acctatgacc gtgatcgtcg tgccaaccgt gagaaaaaac aagataaact
     4501 tgatatcgaa atgattggtt tggttaaaaa gaaaaagaaa aaagtcaaac cgggttataa
     4561 gaagaaaatt caatgggcgg ttgatgaaaa gcgccgtaaa actaagcgtg ctgaaaatcg
     4621 cgctcgcggt cgtgcagagc gtaaagctaa acgccaaaca ttttaataga aattgttgga
     4681 gtactgagct ccaacttttt tatttatgag aacgaactat ctaaaccgaa acactacatt
     4741 aaagactgca aattgcgatt aaaaatggta taatgataaa gttatatagt cccgataaga
     4801 tggtaggtat ttattacgaa gagttttcct atcagtagtt tgcaattcgc aaagaatgac
     4861 ggcttcgagg tcgctcgtct ttctacggtt gccgccatac tgcggtcacc ctatgcgcct
     4921 tactagcttc agaaataaaa aagtatcgtt tttatttctg aagctagtaa ctcttagata
     4981 atggaaattc ctatcagtac tttgtaactc tataacaata ttttttaagg ggggacattt
     5041 ttatgtcaga acgtaaatta ttcacgtctg aatctgtatc tgaggggcat ccggataaga
     5101 ttgcagacca aatttcagat gcgattttgg atgctatttt agcaaaggat ccagaggcgc
     5161 acgttgctgc tgaaacagct gtatatactg gttctgtcca cgtttttggt gaaatttcta
     5221 caaatgccta tgtggatatt aaccgtgtgg ttcgtgatac cattgcagag attggttata
     5281 ccaatacaga atatggattt tctgctgaga cggtgggagt acacccatct ttggtggaac
     5341 aatctcctga catcgctcaa ggtgttaacg aagccttgga ggttcgtgga aatgctgatc
     5401 aagatccact ggacttgatt ggagcaggtg accaagggct catgtttgga tttgcagtag
     5461 atgaaacaga agagctcatg ccattgccaa ttgcactcag tcataaattg gttcgtcgtc
     5521 tggcagaact tcgtaagtct ggagaaatta gctatctccg tccagatgca aaatcacaag
     5581 ttacagttga gtacgatgaa aatgaccgtc cggtacgtgt agatacagtc gttatttcta
     5641 ctcagcatga tccagaggcc actaatgaac aaatccatca agatgtgatt gacaaggtca
     5701 tcaaagaagt tattccatct tcttatcttg atgataagac aaaattcttt atcaatccga
     5761 caggtcgttt tgtaatcggt ggtcctcaag gggactcagg tttgactggt cgtaagatta
     5821 ttgtagatac ttatggtggc tactctcgtc atggtggtgg tgccttctct ggtaaagatg
     5881 cgactaaggt ggatcgttca gcctcttatg cggctcgcta tattgccaag aatatcgttg
     5941 cagcaggcct tgctaagaag gcagaagtgc agttggccta tgctatcggt gttgcgcaac
     6001 ctgtttctgt tcgtatcgat actttcggta caggaacagt agctgaaagt caacttgaaa
     6061 aagcggctcg tcaaatcttt gaccttcgcc ctgcagggat tatccaaatg ctggacctca
     6121 agcgtccaat ttaccgtcaa acatcggctt acggtcacat gggacgtaca gatattgatc
     6181 ttccatggga acgtttggat aaggtagatg ctttgaaaga agcagtaaaa taagatttta
     6241 agaggggaac gtcctctctt ttttatagtt tttaactata ctgggatact gttctgaaaa
     6301 tccattttgc gaaagtagag atttacatgt ataatggatt gaaactagaa tagtacacct
     6361 caacttctaa aacattgtta gaaatcgatt tgactgtcct gatcgatttc tcctgttctt
     6421 gtttcatttt actatatttc tttaaaaatg ataaaggttg agatttctcc tcgtaataga
     6481 taatcatggg gatatttcaa tccaaagttt tattcgttat cacttgacta ttgcaaggtt
     6541 ttctagagca acagagtcat ggaatggact catggttgag atttctcctt gttgcttgga
     6601 cttcattcaa aagtctgtta cccaagcctt gttcaaactt ccaatacact agctgtttcc
     6661 atagcatgac ttctgtacta gactttcttt tccgaataaa tagatagaac cacagaatct
     6721 agtaaaccta gaattaaaat tatggtataa tattagcaat aaaagaaatc tggaggatta
     6781 gaatcatggt atcaacgaaa acacaaattg ctggttttga gtttgacaat tgcttgatga
     6841 atgcagcagg tgtggcttgt atgacgatag aggagttaga agaggtcaaa aactcagcgg
     6901 caggaacctt tgttactaag acagcgacct tggacttccg tcaggggaat cctgagccac
     6961 gctaccaaga tgttccactt ggttccatca actctatggg cttgccaaat aatggcttag
     7021 actattattt ggattatctt ttagatttgc aggaaaaaga gtcgaaccga actttcttct
     7081 tatctctggt cggcatgtct ccagaggaaa cccatactat tttgaaaaaa gtccaagaga
     7141 gtgattttcg tggtctgact gagctaaatc tttcctgtcc aaatgttcca ggtaaacctc
     7201 agattgccta tgattttgag acaacagacc ggattttggc agaagtgttt gcttacttca
     7261 ccaaacctct tggaattaaa ttgccacctt attttgatat tgttcacttt gaccaagcgg
     7321 cagctatttt caacaaatat ccgctcaagt ttgtcaactg tgttaactct atcggaaacg
     7381 gcctctatat agaagacgaa tctgtcgtta ttcggcctaa gaatggtttt ggtggaattg
     7441 gtggagaata catcaaaccg actgctctag ccaatgttca cgccttttat caacgtttaa
     7501 atcctcaaat ccaaattatc ggaacaggtg gcgttctgac tggtcgagat gcctttgaac
     7561 acatcctctg tggagcaagt atggtgcagg tgggaacgac ccttcacaaa gaaggcgtca
     7621 gtgcttttga ccgcattacc aatgaactga aagcaatcat ggtggaaaaa ggctacgaga
     7681 gcttagaaga tttccgtggg aaattgcgct atattgacta aattaaatcg aaaaatctga
     7741 agaaaggaga gacgatgcta gccattgaag aaagtcagaa gttgacttta tcaaatttac
     7801 cgagcctgag cctatttaca gggacagatc agggtcagtt tgaagtgatg aagagtcaag
     7861 tgttgaaaca gattgggtat gattctgctg acctcaactt tgcctacttt gatatgaaag
     7921 aagtagttta caaggatgtg gaactggagt tggtcagcct tcctttcttt gcggatgaga
     7981 aaatcgtgat attagattat tttatggata tcacgactgc taagaaacgc tttttgacag
     8041 atgatgagct taagtcattt gaggaatacc ttgacaattc ttctccaaca accaagttga
     8101 taatctttgc agaaggaaag ctggatagca aaagacggtt agtcaaatta cttaagcgtg
     8161 atgccaaggt cttcgatgca gtagaagtaa aagaacaaga attgcgccag tatttccaaa
     8221 agtggagtca gaaacaaggt ctgcagttta ccaatcattc ttttgaaaat ctcctcatca
     8281 agtcggggtt tcaatttagc gaaatccaga aaaatcttct ctttttacag tcctataagg
     8341 cgaattctgt tattgaggaa gaggatattg ttaacgcaat tcccaagacc ttgcaggaca
     8401 atatttttga tttaactcag tttattctga ctaaaaagat ggatcaggcg cgcgatttgg
     8461 tgagagactt gaccttgcaa ggggaagatg aaatcaaact gattgcagtc atgctgggac
     8521 aatttcggac ttttactcag gtgaagattt tggcggagtc tggccaaaca gaatcgcaga
     8581 ttgcaagtag tttaggtagt tatctgggac gtaacccaaa tccttatcaa atcaagtttg
     8641 cattaagaga ttcgagagga ctttctttga gctttctgaa gcaagctatt tcctatttga
     8701 ttgagacaga ctatcagatt aagacaggtc tttatgaaaa aggtttcctt tttgaaaagg
     8761 cactcttaca gattgctagt caggtcaatt gacatttgtt gaaactacaa cccgcgtcag
     8821 gattatcttg tcgtgggttt cttgctgatt tgcttatttt attagaaagt atgtcagtga
     8881 tttccttatc tataagcaaa aaacttgaaa aaagtgaatg tttgcgttat cattttcata
     8941 tagaaagaaa aagaggtatt acagatggct attatcttac cagaacttcc atatgcatac
     9001 gacgctttgg aaccatacat cgatgcggaa acaatgcatt tgcaccatga caaacaccat
     9061 caaacttatg tcaacaatgc caatgcagct ttagaaaaac accctgaaat cggtgaagac
     9121 cttgaagcct tgcttgctga tgtagaatct atcccagctg atatccgtca agcacttatc
     9181 aacaatggtg gcggacactt gaaccacgct cttttctggg aattgatgac tcccgagaaa
     9241 acagctcctt cagcagaact ggcagcagca atcgatgcaa catttggttc atttgaagaa
     9301 ttccaagcag ccttcactgc agcagcaaca actcgttttg gttcaggttg ggcatggttg
     9361 gttgtcaaca aagaagggaa acttgaagtg acttcaacag caaaccaaga cacaccaatc
     9421 tcagaaggta aaaaaccaat cttgggcttg gacgtttggg aacatgctta ctacgtgaaa
     9481 taccgcaacg tgcgtcctga ctacatcaaa gctttctttt cagtaatcaa ctggaataaa
     9541 gtagatgaat tgtacgcagc tgctaaataa tgatagttgg agggaagaat tgttcttctc
     9601 tttttaggtt ataagattct ggtctgacaa aatcgtcaga cttttttcat ttttatgaga
     9661 aacgtgctaa ctgctagaaa ttatggtaga ataaagtatt aagtaatcgt ggaaaaagga
     9721 tatctatgcg aaaagaaatt gcacctgaat tatacaacta taacaagttt cctggtccgg
     9781 agttccattt acacggggat aaggtcgaaa cggaagggat agctttttcc ttggttgaaa
     9841 atatcaagga tgcctttgat gtgacgactt ttaatcagcg tttttcagaa gtcttaacca
     9901 agtttgatta tatcgtgggg gactggagca acgaacagct tcgcctacga ggtttttaca
     9961 aggatgaccg aacagaagaa aaacttgaaa aaatcagtcg tttacaagac taccttttag
    10021 agtattgtag ttatggttgt gcctattttg tcttagaaaa tgaagcccct aagcgagcat
    10081 catttgacaa gaaaatgcgt aagacggaag aagaaacacc ttctagaaaa ggaaagaaac
    10141 cgactcaaac taaacgaaag tcgaatgcag ataagaaaaa tagacgtcgt cagaaagacc
    10201 agcattctca gaaagaggac aaggaacaac gtcattttgt cattcgtcag aagtgagtag
    10261 agaataagga gaagaaatga aaccctcaat tcatagtttg gcacatcaaa ccatgcagga
    10321 atgggtattg gagcagggag aaaagaaatt ccgtgcagat caaatctggg aatggctcta
    10381 ccgtaaacgt gtgcagtcat ttgaagaaat gaccaacctt tccaaggatt tgattgctaa
    10441 gctcaatgac cagtttgtgg tcaatccctt gaaacaaggt attgtgcaag agtctgctga
    10501 tggtacagtc aaatatctct ttgaattgcc tgacggtatg ttaattgaga ctgtactcat
    10561 gtgtcaacac tatggtttat ctgtctgtgt gaccactcag gtcggctgta atatcggttg
    10621 taccttctgt gcctctggtt tgattaagaa gcagcgtgac ctcaataacg gtgaaatcgt
    10681 agcgcaaatc atgctggttc agaaatactt tgatgagcgt ggtcaggatg aacgcatcag
    10741 ccatatcgtt gtcatgggaa tcggtgagcc ctttgataat tacaacaatg tcttgaattt
    10801 ctttcgtact atcaatgatg ataaaggaat ggctatcggt gctcgtcaca tcacggtttc
    10861 aatctcaggt ttggctcata aaattcgtga ctttgctgat gaaggggttc aggtcaatct
    10921 tgccgtgtct cttcacgcac ccaacaatga acttcgttca agtatcatga agattaaccg
    10981 tgcctttcc
//
LOCUS       DAVAZT010000064        10796 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVAZT010000064 DAVAZT010000000
VERSION     DAVAZT010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10796
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.064"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            140..430
                     /locus_tag="VQT45_001817"
     CDS             140..430
                     /locus_tag="VQT45_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360090.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEYPELYAVAQTSGEIPEKNAKNCVRLSQLSLNKR"
     gene            454..1170
                     /locus_tag="VQT45_001818"
     CDS             454..1170
                     /locus_tag="VQT45_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2360091.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSIGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIISDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(1299..2114)
                     /locus_tag="VQT45_001819"
     CDS             complement(1299..2114)
                     /locus_tag="VQT45_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HET2360092.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(2111..3016)
                     /locus_tag="VQT45_001820"
     CDS             complement(2111..3016)
                     /locus_tag="VQT45_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HET2360093.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGMLFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
     gene            3414..5543
                     /locus_tag="VQT45_001821"
     CDS             3414..5543
                     /locus_tag="VQT45_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HET2360094.1"
                     /translation="MDKKYEKISQDLGVMLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRAQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYTAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVSVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
     gene            5530..5979
                     /locus_tag="VQT45_001822"
     CDS             5530..5979
                     /locus_tag="VQT45_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HET2360095.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            6038..6310
                     /locus_tag="VQT45_001823"
     CDS             6038..6310
                     /locus_tag="VQT45_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET2360096.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(6664..6855)
                     /locus_tag="VQT45_001824"
     CDS             complement(6664..6855)
                     /locus_tag="VQT45_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360097.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            7283..8041
                     /locus_tag="VQT45_001825"
     CDS             7283..8041
                     /locus_tag="VQT45_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2360098.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            8043..10031
                     /locus_tag="VQT45_001826"
     CDS             8043..10031
                     /locus_tag="VQT45_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2360099.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYSVKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNEGVKEQKALTLNDHQFSVKEEFTKDFIVNHVPNQF
                     NILTADYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVNASEAEQLKVAEEYEKYLQKF
                     NAQLNTEGNYVYGSTLADASAQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFLHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(10073..10717)
                     /locus_tag="VQT45_001827"
     CDS             complement(10073..10717)
                     /locus_tag="VQT45_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HET2360100.1"
                     /translation="MLRAGVLDANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNEEFKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLEQLFSI"
BASE COUNT         3341 a         2021 c         2255 g         3179 t
ORIGIN      
        1 actactatac catattttgt ttcgcaggaa gtctaatgct aaaatcttat cagtgagaag
       61 atttcttaaa gtttattctt tgtagtttca tctgtattag tacataattt aacttagaga
      121 aaataggagg actaatcgaa tggaattaaa agattttaca gaaaaagaac aggaaatgat
      181 taagaaaagg cttacaatgt ctaatattag tgacaaagaa actactgaga agattctggc
      241 gctagtccca caagacttga ttaagcgaat cccgtttttt gtcagaaaac atgctacaac
      301 acgtacgatt aaacgtattt caattgaata ccctgaactc tacgctgtag ctcaaacaag
      361 tggtgagatt ccagaaaaaa acgcgaagaa ttgcgtcaga ttatcacaac tatctttgaa
      421 caaaagatga ataagcatag tattaagtag agaatgaaaa aatattttat tggcggtttg
      481 ggaagcaatg cctatcatag caaggatttt cttcaagaac tagattcgca ggtctatttt
      541 ctaaatccat atgaaaagca tcttcgagat gaaacagaat tgaaatcatg gtttaaaaat
      601 gagattgtag aggaagaatc tatctgtctg ataggtcatt ctattggagg cgatttagct
      661 cgttatttcg catcggaatt tgaagaagta aagaaactga ttcttttgga tggtggctat
      721 ctagatttag ataagatttt acctttggat acagagttag aggaaactaa aaattatatc
      781 aaatctcaaa ttatttcgga cttagatgtt cttacttcta aagaaaaatc tgaagcaaag
      841 cattggtcag aaaatatgga gaaagctgta agacagtcct atcactggaa tgttgagtat
      901 aatagatatg agttggctat aaattatgaa aatatagaag cgatactccg cctacggaga
      961 aaaatacaag cttttaagag agaagtggga gataccttgt ttattagtcc tcgctatcct
     1021 aatgaagcta catggagaga ggaagcccta aaagaattgc cagactattt tgatactatt
     1081 tttttagaaa actttggcca tgagctttat actcaagcac ctaaagaaat cgctagtcta
     1141 atgaatgagt ggctcgctta ttttctatga gctacttgta ttgctggaaa tggtataaga
     1201 tgaaaatcta caagtcacta attttcatat aacaaaaaac gaacaggctc tttttctgtt
     1261 attcagaaga gaacttgttc gtttttatct tgattttctt aaaaagctct atatacatag
     1321 ggattttctg gtttatcgac tttggtaaag ctgtcgattt ccaaggttgg aaggttttgt
     1381 ttgagttctt tatggtagtg attgaccagt tttcctttgg ctgttatcca agtgttgttt
     1441 tcatactgcc gggtattgcc cttggtcagc aatccataga caccagaatc tgcgatacag
     1501 tggataatgc cgaatcggaa cagaaattga ctattggcat gactggggtc gttatagaca
     1561 aagcctgtaa actggattgt cttgccctca aactcatctg gatagtcgta gatagcctcc
     1621 atgacttcca tatagttttc attagtgatc tgaatactat cttgggataa gtatttatcc
     1681 gccgccgttc gcatttcctt ttcataggct gattttgaaa aataagaact ggtatctggt
     1741 ttcaaatatt ggcttgtcgt cccttcgctt gtctgaatgg ctagatctgt tccttccgat
     1801 agggggaaat gataaccttt agcagaaacg gtctgagaat ccaagctaac agttgggaaa
     1861 gttaagccga tgacaagtgg aatagccaga agagaaatac tcgtcatctt ggccaatcgg
     1921 ctgttcagat gactgtgggt tttgacttgc ttcatccaga tatacaattg aacaattgcc
     1981 aagataaagg aaagcaccat ggagatatag gccagatagg aatagtgcat gttgatgtac
     2041 tggtttagtt tgcccgacag atggaggtaa atagtcagtt caaaatagcc agctaaaact
     2101 aaaaatcgaa tcataggatg actccaatca agagagaata gactaagacg acaagagtta
     2161 caatcgttat gaagtgactg ataaatcgtg ctttcaagta atttttcatc atgagaatat
     2221 ttttgatatc cagcattgga ccaatgacga gaaaggccag aactggtgcc aaaccgaaac
     2281 tcgagagaag agaagcacct ataaaggcat ccgcctcact acagagcgaa agaagaaagg
     2341 ccaaaatcat caagagcagg atggcaaaaa gaggagtcgc actgatagag gtcagaatcc
     2401 gagtcggaac gtagacctgt attatagaag caaagaggca gccaaatacc aaataacgcc
     2461 ccgtatcaaa aaattcatca atggcctgca caaagacttg aaaaactttt tttgcagaac
     2521 tcaagtaaga aaaatcatgc tcatgacaag ccagacgatt ttctttctga atcggttctt
     2581 gccagaaaaa tcctagaaaa attcctagta ttacagccac aagaatggaa cccagagctc
     2641 gtaatagggc gacatggaag gagttgccaa aggcagaata ggtcgcaaaa agaacaatgg
     2701 gattgataac aggtgctgtc acaagaaaag gaacggctgt gtaactggga accttttttt
     2761 ccagaaaacg attgatgatg gggacgattc cacattcaca agaagggaaa agcataccga
     2821 caaaggtccc aaaaaagatt ctcccccaac gatttcgagg gagaaaatga taaaccttgt
     2881 caggtgtgat ataaacttca atcagccctg agacaatgct tcctattaga acgaagggaa
     2941 gggcttcaat gataatggag agaaaaatgg ctccagtttg aagtacacta gatgggagtt
     3001 gttgaaaagc agtcatctag tttttctttt ctgctttggc ttttttctct ttgtcatcag
     3061 ggaaagtaac ttgtttcaaa tcagggagtt tagcaaactc ttcaaacatc ttgtccaagt
     3121 cgtctcgttt tgtaaatttt acagccatag gtgtacctcg attctaaagt ctacctctat
     3181 tatactatta ttttgcggaa aagggagttt tttaatttgt tttcgatagt tgatacactt
     3241 cgaaaatctc ttcaaaccac gtcagcttcg ccttaccgta tatatgtgac ttatccacaa
     3301 cctcaaaaca gtattttgag cagcctgcgg ctagcttcct agtttgcttt ttgattttca
     3361 ttgagtatga aaaggattgg agaaagcctt ccagcttgtg gtataataga tttatggata
     3421 aaaaatatga aaaaatctct caggatttgg gagtgatgtt aaagcaaatt gataccgttc
     3481 taagtttgac agctgaaggg gcgactattc cctttatcgc gcgttatcgc aaggacatga
     3541 ctggtagtct ggatgaggtg gcgattaagg ctattattga tttggataaa agtctgacaa
     3601 atctcaatga ccgtaaggaa gctgtcttag ctaagattca agaacaaggt aagttgacca
     3661 aggaattgga agaagctatc ttagttgccg aaaaattagc agacgttgaa gaactctatc
     3721 ttccttataa ggaaaagcgt cgtaccaagg caaccattgc ccgtgaagct ggactctttc
     3781 ctcttgctcg tttgattttg cagaatatag ttgacttaga gaaagaagct gaaaagttcg
     3841 tctgtgaagg atttgcgact ggcaaggaag ccttgaccgg tgcagttgat attttggtcg
     3901 aagccttatc ggaagatgtg accttgcgtt ctatgactta tcaggaagtg ctgagacact
     3961 ctaaacttac ttctcaagcc aaggatgaaa gtcttgatga aaagcaggtt tttcagattt
     4021 attatgattt ttcagagaca gttggaacta tgcaaggcta tcgtaccttg gctctcaatc
     4081 gtggggagaa acttggtgtc ttgaagatcg gttttgaaca tgcgacggac cgtattcttg
     4141 ccttctttgc tactcgtttc aaggtgaaaa atgcttatat tgatgaagtt gttcagcaat
     4201 ccgttaagaa aaaggtcttg cctgctatcg agcgtcgtat tcggacagaa ttaactgaga
     4261 aagctgaaga aggagctatc caactttttt ctgacaatct gcgcaatctc ctcttggttg
     4321 ctccactgaa agggcgcgtg gttcttggat ttgacccagc ctttcgtaca ggtgccaagt
     4381 tagctgtcgt ggatgcaaca ggaaaaatgc tgacaactca ggttatttat cctgttaaac
     4441 cagcatcagc tcgtcaaatc gaagaagcca agaaagattt agcagattta attggtcaat
     4501 acggtgtaga gattattgcc attggaaatg gaacggccag tcgtgaaagt gaagcttttg
     4561 tagcggaagt tctgaaagat ttccctgaag tcagctatgt tatcgttaat gaaagtggtg
     4621 cttctgtcta ttctgccagc gaacttgctc gtcaggagtt tccagacttg accgttgaaa
     4681 aacgctctgc catttctatc gcccgtcgtt tgcaagatcc tcttgcggaa ttggtcaaaa
     4741 tcgatcctaa gtcaattggt gtcggtcaat accaacacga tgtcagtcag aagaaactat
     4801 ctgagagtct ggactttgtt gtcgatacag tggttaacca agttggtgtc aatgtcaata
     4861 cagctagccc agctcttctt tcacacgtag ctggactcaa caaaactatc tctgaaaata
     4921 ttgtcaaata ccgcgaggaa gaaggaaaaa tcacttcacg cgcccaaatc aagaaagttc
     4981 ctcgtctggg agccaaggcc tttgagcagg ctgctggttt ccttcgtatc cctgaaagta
     5041 gcaatatcct tgataataca ggagttcacc cagagaatta cactgcagtt aaggaactct
     5101 tcaaacgttt agatattaaa gacctaaacg aagaagccca aagcaaactc aagtcccttt
     5161 cagtcaagga aatggctcaa gagctagacc tcggtccaga aacccttaaa gatatcattg
     5221 cagatcttct caaaccaggt cgagatttcc gtgattcctt tgacgcacct gtgcttcgcc
     5281 aagatgtcct agatatcaaa gacctagtgg taggtcagaa gctagaaggt gttgtgcgta
     5341 acgttgttga cttcggtgcc ttcgttgata tcgggattca cgaggacggc ttgattcata
     5401 tttctcatat gagtcgcaag tttatcaaac accctagtca agtggtgtca gttggagatt
     5461 tggtgaccgt ttgggtcaag aaaattgata ctgaacgtga aaaagttaat ctgtcgctcc
     5521 tcgctccaaa tgaaactgac tgattatgtc aagcaggttt cactagaaga cttcgggaga
     5581 gcttttatcc atcatgtcca gtggaatagg cgtctacgtt cgacaggtgg gcgatttttc
     5641 cccaaagatg ggcatctgga ttttaatccc aaggtttatc agaaactggg tatggaggtt
     5701 tttaggaaaa ttgtccgaca tgaactctgt cattatcacc tttatttcca agggaagggc
     5761 tatcaacaca aggatcggga ttttaaggaa ctgttgaaag cagtggatgg attaaggttt
     5821 gtaccatcct tgcccaatag taactctaaa ccactcaagc tttatcgttg tcaatcctgc
     5881 cagcaaaggt atcagcgcaa gcgtaggatt gataccaaac gctatcgctg tggactttgt
     5941 cgaggtaaat tgcttctgat aaatcagcct gaggactgat gaaagccgag cctccccgtg
     6001 atatactatg tctaacctag cagaaagagg aaatatcatg aacagtaaat tttataaaat
     6061 gagacgcaat cgcatgattt caggagttct ggcaggtctg tcagacaagt ggaattttga
     6121 tgttacccta gttcgtttct tgtttgccat ttttacagtt gcaaactttg gacttggcgt
     6181 gattatctat atcatcctag cttctatcat gcctaccaag gaagaaatcg aagcagaaat
     6241 gtacggaaca ggcccacgta aacgcaaaga agcccaagcc attgacgaca atgaaggctg
     6301 gttttggtga ggttctacag aagatttgga ataagcaaaa agctttaaat caatagtcta
     6361 aactgcttga tttaaagctt ttttactttt atactcaata aaaatcaaag tgcaaactag
     6421 gaagccagcc acaggctgta atttagtcgg caatgtgaag ttgacatagt ttgcactttg
     6481 atttttgaat agtattaata atatttcgcc agcttcatcc acaaactata gtggattgga
     6541 actagaatag tacacctcta cttctaaaac attgttagaa atcgatttga ctatcctgat
     6601 cgatttgtcc tgttcttatt tcattttatt ataaaagcag taatttaaac tcagtttttt
     6661 aatctatttt tgctgctgag acaatacatt tttggaaaaa tggtggatgc tgataacaac
     6721 tgataaccag caaataacat aagcagtgcc ggtaaattct gtaccgataa agtgtgtgtg
     6781 ttcaactaag agctgaccga tgaatggaga gagcagatag agaagtccga tgagtatatg
     6841 ttctttgtgt ttcattaaag cgcaccttct ttccttatag gttgaacgac ttgcaagtgt
     6901 taaattgaat ggtatgttat ctaggtaagc ttactcaaat gatagttccc gcttcctcct
     6961 ttccaaagta agccttttca tacttatatt ttacaacttt aaaaatagga aatcaaatca
     7021 ttttctaagt aattttgctt atatttcacc caatcttaca aaaatgtaag attaaagtct
     7081 cttttgtaag gttaggttat ggcaagcggt ctttttttga tgtaaactag actcataaag
     7141 aacaaaggag taacatcatg aaacaaatct tacataagaa aactagaaaa ccaagtcaca
     7201 aagaaattga gcgcgttcag ctgggatgca ctatgatgca agctacattt catttgatgg
     7261 gatattaaga aaggagattc tcatgacact tttagatgta aaacacgttc aaaaaattta
     7321 taaaacacgt tttcagggca accaagtaga agccctcaag gatattcact ttaccgtcga
     7381 aaagggtgac tacgttgcca tcatgggtga gtctggttct ggtaaatcaa ctcttctcaa
     7441 tattctagct atgctggata aaccaagtcg tggtcaggtt tacttgaatg gaactgacac
     7501 cgcaaccatt aaaaattcac aggcctctag cttccgtcgt gaaaagttgg gctttgtctt
     7561 ccaagacttt aacttgctag atactctatc tgtaaaggac aatatcttgc ttccgcttgt
     7621 cttgtcaaga agacctatta cagagatgat gaagaaattg gtggtgacag ctgagaatct
     7681 gggaataaac caattacaag agaagtaccc ttacgagatt tctggtggcc agaaacagcg
     7741 tgtagcagta gcacgcgcca tcatcactga acctgaaatt ctccttgcgg acgaaccgac
     7801 aggagctctt gactccaagt catctgcagc cttacttgat gtctttgatg aaatcaatga
     7861 gcgcggccaa accattctca tggtaaccca ctcaacagca gcagctagca gagctaaacg
     7921 tgtactcttt atcaaagacg gcattcttta caatcaaatc taccgtggag agaagacaga
     7981 acgtcagatg ttccaagaaa tctctgatac cttgactgtc atggcaagcg aggtgaatta
     8041 gtatgtttcg attaaccaat aagttagcgg tatcgaactt gattaaaaac cgcaaactct
     8101 actatccttt tgcgctggct gttctcttgg cagtcactgt cacctatctc ttttactctc
     8161 taaccttcaa tcccaagatt gctgaaattc gtggaggaac aaccattcag gctacacttg
     8221 gatttggtat gtttgtcgtc acccttgcgt cagccattat cgttctctat gccaatagtt
     8281 ttgtcatgaa gaaccgttcc aaggaactag gaatttatgg catgttgggc ttggagaagc
     8341 gtcatcttat cagtatgacc tttaaggagt tagtggtatt tgggattcta actgttggag
     8401 cgggtatcgg tattggagcc ttgtttgaca agttaatttt cgctttcctg ctcaaactaa
     8461 tgaaattgaa ggttgagctg gttgctacct tccagacgaa agttgtcatt acagtgcttg
     8521 ttgtcttcgg tttgattttc ctaggcctca tgttcctgaa tgcccttcga atcgcccgta
     8581 tgaatgccct ccagctctct cgtgagaaag ctagtggaga gaaaaaaggt cgcttccttc
     8641 ctctccaaac cattcttggt tccataagtt taggaattgg ctattatctt gcccttacgg
     8701 taaaagatcc tcttacagcc ttaacaacct tcttcatagc tgttttactg gttatctttg
     8761 ggacttatct cttgtttaat gcagggatta ccgttttcct ccaaatctta aagaaaaata
     8821 agaaatacta ttaccaacca aataatctca tatctgtttc taacttgatt ttccgtatga
     8881 agaaaaatgc agttggacta gccaccatcg ctatcttgtc aacaatggtt ttggtaacca
     8941 tgtcagcagc gacaagcatt ttcaattcct cagaaagctt taaaaaagtt ctaaatcctc
     9001 atgattttgg ggtttcaggg caaaatgttg aaaaagaaga cttggacaaa ctcttgagcc
     9061 agtttgcaag tgacaaaggt tatagtgtca aagagaaaga agtacttcgt tacagtaact
     9121 ttggtattgc aaatcaagaa ggaactaagt taactatttt tgaaaaagga caaaaccgtg
     9181 tccaaccaaa aacagttttc atggtatttg accaaaaaga ttatgaaaat atgactggtc
     9241 aaaaactgtc tctatcagga aatgaggtcg gactctttgc aaagaatgag ggagttaaag
     9301 aacagaaagc tctaactcta aatgatcatc aattttctgt aaaagaagaa tttactaaag
     9361 attttattgt caaccatgtt ccaaatcagt ttaatatttt gactgctgat tacaattacc
     9421 ttgttgtacc tgatttacaa gcctttttgg atcaattccc agattcggct atctataatc
     9481 agttttacgg tggtatgaat gtaaatgcca gtgaagcaga acaactcaag gtcgctgagg
     9541 agtatgaaaa atacttacaa aagtttaatg ctcaattaaa cactgaaggt aactatgtgt
     9601 atggtagcac tctagcagat gctagtgctc agatgagtgc cctctttggt ggtgtcttct
     9661 ttatcggtat tttcttatcc attatcttta tggtcggaac cgttctggtc atctactaca
     9721 aacaaatttc tgaaggatat gaagaccgtg agcgctttat tatcttgcag aaagtcggtt
     9781 tagatcaaaa gcaaatcaag caaaccatca acaaacaggt tttaactgta ttcttccttc
     9841 ctttgctctt tgccttccta catctagcct ttgcctacca tatgcttagt ctgattttaa
     9901 aagtgattgg tgtactggat acgactatga tgttgattgt gaccttgtct atctgcgcta
     9961 tcttcctcat cgcctatgtg ctgattttca tgattacttc aagaagttat cgcaagattg
    10021 tgcaaatgta aaaaagatac ctcgacttca aaatcgaggt atttcttgta ttctaaatgc
    10081 tgaaaagttg ttcgagcagg aaggtaactc ccatggtcaa gagaccaata gcaaggttcc
    10141 gaatcatagc tgttttggtt ggggcttttc caagtctagc acttgtgtaa ccagtgagaa
    10201 gaagggccac accgacaata aggacggtag cagggatgcg gtaatcactt ggaaaaatgg
    10261 tcactgacag cattggaggc aaacttctaa ggaaaaaggc aacgaagcta gaaatggcag
    10321 cgtgccaagg attggtaaat tcttcatact caatcccata tttttcctct accagagcct
    10381 tgagtggatt tttaagaaag atcttattag tcaagagttg ggcagaagtt ttgaattctt
    10441 cattttggat ataagcagca tagagggatt ttttggctag ttccctatct tggtctagca
    10501 agagtttttc tcgcgaaacg gcagcttcct cggtatcttt tggagttgaa acggatacat
    10561 attctccacc agccattgaa aaggcaccag ctaagatagc cgcaaatcct gataaaaaga
    10621 taatccagat attggtcgtg gcactggcaa ccccgataac cacaccagca atggaaataa
    10681 ttccatcgtt agcatcaaga acacccgcac gcaggatatt taaacgacct gcaaaatttg
    10741 aatcaatttc gtgatttgtt tctgacgcta aatttcaagt tcaagttagc catcca
//
LOCUS       DAVAZT010000065        10764 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVAZT010000065 DAVAZT010000000
VERSION     DAVAZT010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10764
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.065"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            51..233
                     /locus_tag="VQT45_001828"
     CDS             51..233
                     /locus_tag="VQT45_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET2360101.1"
                     /translation="MKSQKIKVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTIL
                     RLESASIVSELVAGLR"
     gene            533..1372
                     /locus_tag="VQT45_001829"
     CDS             533..1372
                     /locus_tag="VQT45_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET2360102.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            1390..3228
                     /locus_tag="VQT45_001830"
     CDS             1390..3228
                     /locus_tag="VQT45_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET2360103.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPDVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTPAITKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     NLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            3241..4656
                     /locus_tag="VQT45_001831"
     CDS             3241..4656
                     /locus_tag="VQT45_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET2360104.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSAIPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDELNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            5248..6294
                     /gene="pheS"
                     /locus_tag="VQT45_001832"
     CDS             5248..6294
                     /gene="pheS"
                     /locus_tag="VQT45_001832"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HET2360105.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            6294..6803
                     /locus_tag="VQT45_001833"
     CDS             6294..6803
                     /locus_tag="VQT45_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2360106.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            6880..9285
                     /locus_tag="VQT45_001834"
     CDS             6880..9285
                     /locus_tag="VQT45_001834"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HET2360107.1"
                     /translation="MLVSYKWLKELVGIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEILSCEDVPETHLHVCQVNVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKKFADGIQILPENAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMRGVAHEVAAIYDKAVNFKEFTLTETNEAATDALSVGIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SHVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLRRQVRTIAE
                     GAGLTEIITYVLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLEVTYTATAEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSVIEAALQPAAPFVEITKFPAVSRDVALLLKAAVTHQEVIDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEKKVNA
                     EVR"
     gene            complement(9458..10459)
                     /locus_tag="VQT45_001835"
     CDS             complement(9458..10459)
                     /locus_tag="VQT45_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET2360108.1"
                     /translation="MIKTFLSALSVILFVIPIITYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMAAILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIADDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            10615..>10764
                     /locus_tag="VQT45_001836"
     CDS             10615..>10764
                     /locus_tag="VQT45_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2360109.1"
                     /translation="MQDNYTTKGKHLTIDSRRLIERWKKEGKSNREIASLLGKVPQTI
                     HTEIKR"
BASE COUNT         3449 a         1734 c         2287 g         3294 t
ORIGIN      
        1 accccaaaag ttagattttt tctgtctaac ttttggggtg tagttcacag ttgaagagcc
       61 agaaaattaa agtgtctttt actcaatcaa aaatagtaac gcctattctt ttggtgaata
      121 agactattgt ttggtatggt gcaatgccat tattagggaa ggtagatgag atgaccatat
      181 tacgtttgga atcagctagt atagtttctg aactagtggc aggtttacga tagagaaaat
      241 ttttaaaaat ttctatgtat gattttcatt tctttagtga gactgttgcc attatcacat
      301 tcgaatcaca caaaataaaa aaatttctac aagtacttga caaatagatt gaaatatcat
      361 aaaatgaaaa tggttacaga gttattaatt atttaagctt catgtcacca ttaaaaattg
      421 aaataaaagg atgttatcac taatacaagt gagcaggaac ctatttaatc acatcggaag
      481 aagtttcttg atgtttttaa gtaggttcct tttattttaa aagggaaatt ttatgatcat
      541 aaaacgaata ctaaaccaca atgccgtaat tgcgcaaagt aaaaaagata tcgatattct
      601 tctttttgga aggggcatag cttttggaag aaaaactgga gataaagtaa atccaattga
      661 tattgagaaa agtttttttc tcaaaaatag agataatatg acccgtttta cagagatgtt
      721 tattaacgtt cctttggagt tggtgtacat caccgaaaaa ataattaacc taggtaaaat
      781 aacattgggt aataattttg atgaaattat ctatattaat ttaacggatc atatttcttc
      841 gagcatagaa cgttataaag aagggattat tatttcgaat cccctacgct gggaaatatc
      901 gaaatattat aaagaagaat ttgaacttgg gaaaagggct ttacaaataa taaaaaaaga
      961 gttaggtatt gaacttccaa ttgacgaagc tgcattcata gcgctacatt ttgttaatgc
     1021 taatttagaa aataattttc aagagtcgta taaaatcact gaaataatta tgggaattga
     1081 gaaaatcatt caagatttct attgtactga gtttaaccaa gattctattg attattatag
     1141 attcataact catataaaat tatttgctca tcgcttggtt gaaaatacaa cttattgtga
     1201 cgatgatgat gaagacttgt tagcattaat gaaaaataaa tatcctagag aatatgaatg
     1261 tggtgaacag gtggcaatgt ttatacaaac tgagtacaat tatttgctga cttctagtga
     1321 attagtttat ttgatggctc atattcgtcg cttaacaaaa aatttagatt aatagaatag
     1381 gagaatacca tgagttataa agatacggta caaaaaatcc tcgatgtaat tggaggtgaa
     1441 aaaaatgtca atagagttac ccattgtgta acacgtttaa gattagaatt aaaagatgaa
     1501 aatttagtca atgatgatga tgtgaagaag ataccagatg taataggtat tatgaaaaag
     1561 aatggacaat atcaaattat acttggtaat gatgtagcta attattataa agaattcgtt
     1621 aaacttggca attttgaatc cgattcagtt gttcaagggc acaaagggaa tattttagaa
     1681 agaatcattg agtatatcgc tggttccatg actccaatca ttccagcaat gttaggggga
     1741 ggtatgttga aagtcttggt aatcatttta ccaatgcttg gtatattgca atcagattct
     1801 cagactattg cttttttgac attttttggg gatgctccat attatttctt accgctgtta
     1861 ttagcttatt ctgcatcaca aaaattaaaa gtaacatcta cattagctat gtctgtagca
     1921 ggtgtacttc tccatccaaa ttttgttcaa atggtgcaat cagggaatcc tcttagttta
     1981 tttggtgcac ctgtgacacc agctagttat ggttcatcag tcgttccaat tcttattatg
     2041 gtttggttga tgaaatatat tgaaaaaata attgctaaat taacaccagc tattactaag
     2101 agttttttgc aacctacgct agtattatta gtatcaagct gtattgcctt agttgtagtc
     2161 ggacctattg gagtaattgt tggtgaagga ttatcaaatc tagttgggca aatgtatggt
     2221 gtagctggat ggcttacatt agctattctt ggtgctatta tgccatttat tgttatgact
     2281 ggaatgcatt gggcttttgc acctattttt ttggcggcat ctattgctac tccagacgta
     2341 ttaattcttc cagcaatgtt agggtcaaac ttagctcaag gggctgcttc gatggctgtt
     2401 gcattaaaga gtaaaaataa taatacaaaa caaattgctt ttgcagcagg tttctcagcc
     2461 ttacttgcag ggattaccga acctgcatta tatggtgtga ctttaaaata taaaaaaccg
     2521 ctttatgcag ctatgattgg tggtggatta gcgggattat ttgcaggtct tactagtgtt
     2581 aaagcatatc tatttgctgt cccatctttg atagcgttgc ctcaatttat ttattctgat
     2641 gtgccatcaa atattgtaaa tgctttaatt gtggcggtca tttcggttgt tattaccttt
     2701 gtattagctt atatatttgg aatcgatgaa gaagagagtt ctagcaattt agaagttaaa
     2761 gctggagttt caaataaaaa aatgatattt tctcctatat caggagaaat cattccgtta
     2821 agcgatgtcc aggataaaac attttcagat aaattaattg gagacggagt agcgattatc
     2881 ccaagtgaag gtaaggttta tgcaccattt gatgggaaaa ttacaaatat ttttccgact
     2941 aagcacgcaa ttggattgaa gagtgatgag ggtgttgagt tactaattca tattggatta
     3001 gatactgttg agctaaaagg tcaaggtttt attagtcatg tagaagaagg agacagagtt
     3061 ttcaaaaatc agttgatttt tgaaatgaac ttgaatttaa tcaagactaa aggctacgaa
     3121 acagttacac cagtaattgt aacgaatacc aatgattttc tagatgtatt agtattacct
     3181 aataatcaga caatcgagca ttctaaggaa ttactggtaa tattataatg gaggaaagtt
     3241 atgaccattt ttccagatga ttttctttgg ggtggagcgg ttgcagctaa tcaagtagag
     3301 ggagcatata atgaagatgg taagggctta tcagttcagg atgtgttacc caaaggtgga
     3361 ttaggagaag caacagaaaa tcctacagaa gataacttaa aattgatagg tattgatttt
     3421 tatcataaat ataaggaaga tatatccttg ttttctgaaa tgggctttaa tgtttttcgt
     3481 acttctattg catggagtag aatttttcca aaaggagatg aggaagaacc taacgaagct
     3541 ggtttgaaat attatgatga attatttgat gaactacatg ctcacgggat agaaccactt
     3601 gtaactcttt cacactatga gactccatta tatttagcaa gaaaatatca tggatggatt
     3661 gataggagaa tgattcattt ttatgaaaaa tttgctcgaa cagttttaga aaggtataaa
     3721 gataaagtta aatattggct tacatttaac gaagtaaact ctgttttgga attaccgttt
     3781 actagtggag gaatagatat acctaaggag aatctttcga aacaagaatt atatcaagct
     3841 atacatcatg aattagtcgc ctcgagtttg gttacaaaaa ttgctcgtga gattaattca
     3901 gagtttaagg tggggtgtat ggtattagct atgccagctt atccaatgac tccaaatcca
     3961 aaagatgtat gggcgactca tgagtatgag aatctaaatt atctattttc agatgtgcat
     4021 gttagaggtt attatccgaa ttatgcaaaa agatatttta aggaaaatga cattaacata
     4081 gagtttgcag ctgaagatgc agagttatta aaaaattata ctgtagattt tttatccttt
     4141 agctattaca tgagtgtgac tcaatctgct attccaacac agtataattc aggagaaggg
     4201 aatattattg gtggtttagt aaatccttat ttagagtctt cagagtgggg atggcaaatt
     4261 gatccaattg gactacgtat aattttaaat agatattatg accgttatca aatcccatta
     4321 tttatagtag aaaatggatt aggtgctaaa gatcaactaa taaaagatga acttaataac
     4381 ttaaccgtcc aagatgatta tagaattcag tatatgaaag aacatttatt gcaagttgct
     4441 gaagctctac aggatggtgt tgaaattatg ggctatacgt cttggggatg tattgactgt
     4501 gtttctatgt ccactgcaca actttctaaa aggtacggtc tcatttatgt tgatcgaaat
     4561 gatgatggaa atggcacatt caatcgatat aagaaaatgt cctttacttg gtataaagga
     4621 gtgattgaat caaatggaga atccttattc aaatagtttg tttattgatg attagatatt
     4681 atcacggtta aggcaacatc tcattaaata taaaataaag aggtttggaa gacatcaaat
     4741 tctaaacctc tttattttat agggggatta attaatttaa ttttgttaca gagagccgat
     4801 tataaatagt taacttagga tagattggtt atatatagta gactgaatct aaaatagtac
     4861 gaaacaattg ctaaaacatt tatagaaatt aattttactt tcccaatcga tttgttttca
     4921 tcttatttca atccgctata aagttagata agaataagct aacaagcaga agtaagatag
     4981 gtcttgcaag aatggtaaaa atctgataaa ctaagtagta attgaatagg aatctgaaag
     5041 actagtagcc caagggaagt atatcaggga ggagagccgt gactgcaagc tctctatatg
     5101 aaagctgggt gaattcactt gcgcatggat ttagaaatga aggtctgact tgtcagatga
     5161 aaacggatgg taccgcgtgt caacgctccg agtggagttt ttggcatgtg gttttctttt
     5221 tatctacgag agactgatgg aggaaatatg tcaactattg aagaacaatt aaaagcgctt
     5281 cgcgaagaaa cgctggctag cttgaagcag attactgctg gaaatgaaaa agagatgcaa
     5341 gatttgcgtg tctctgtcct tggtaaaaag ggttcgctca ctgaaatcct caaagggatg
     5401 aaagatgttt ctgctgagat gcgtccaatc atcgggaaac acgtcaatga agctcgtgat
     5461 gtcttgactg ctgcttttga agaaacagct aagctcttgg aagaaaagaa agtcgcggct
     5521 caactggcta gcgagagtat cgatgtgacg cttccaggtc gtccagttgc gactggtcac
     5581 cgtcacgttt tgacacaaac cagtgaagaa atcgaagata tcttcatcgg tatgggttat
     5641 caagtcgtgg atggttttga agtggagcaa gactactata actttgaacg tatgaacctt
     5701 ccaaaagacc acccagctcg tgatatgcag gatactttct atatcactga agaaatcttg
     5761 ctccgtaccc acacgtctcc agttcaggcg cgtgctatgg atgcccatga tttttctaaa
     5821 ggtcctttga agatgatctc gccagggcgt gtcttccgtc gcgatacgga cgatgcgacc
     5881 cacagtcacc aattccacca aatcgaaggc ttggtagttg ggaaaaatat ctctatggct
     5941 gatcttcaag gaacgcttca gttgattgtc caaaaaatgt ttggtgaaga gcgtcaaatt
     6001 cgtttgcgtc catcttactt cccattcaca gagccatctg ttgaggtgga tgtttcttgc
     6061 ttcaagtgtg gtggagaagg ctgtaatgta tgtaagaaaa caggttggat cgaaattatg
     6121 ggggccggta tggttcaccc acgtgtcctt gaaatgagtg gtatcgatgc gactgtatac
     6181 tctggctttg cctttggtct tggacaagag cgtgtagcta tgctccgtta tggaatcaac
     6241 gatatccgtg gattctacca aggagatgtc cgcttctcag aacagtttaa ataatgatta
     6301 gaaaagtaga aatggcagat gttgaggtgt tggctaaaat tgccaaacaa gcctttcgtg
     6361 aaacctttgc gtatgataat acggaagagc agttacagga atactttgaa gaggcttata
     6421 gtctgaaaac tttgtcaact gagttgggaa atcctgactc tgaaacctat ttcattatgc
     6481 atgaggagga gatagctggt tttctcaaag tcaactgggg aagtgctcaa actgagagag
     6541 aattagagga cgcttttgaa attcaacgcc tctatgtgct acaaaaattc caaggatttg
     6601 gactaggtaa gcaactgttt gaattcgcac ttgaacttgc tacaaaaaat agtttttctt
     6661 gggcttggct aggtgtttgg gagcataata caaaagctca agcgttttat aaccgatatg
     6721 gttttgaaaa atttagccaa catcatttta tggttggtca aaaagtagat acggattggt
     6781 tactgagaaa gaaattaagg taagaagaga attcttctat tgaaatgata ggaaaggaaa
     6841 agaaccagtg tggcaatggt cattctggag aactaaatta tgcttgtatc ttataaatgg
     6901 ttaaaagaat tggtgggcat tgatgtgcca tcacaggagt tggctgaaaa aatgtcaacc
     6961 acagggatcg aggtcgaagg tgtcgaatca ccagctgccg gtctttcaaa aattgtcgtc
     7021 ggtgagatct tgtcttgcga agatgtgcca gaaactcacc ttcatgtttg tcaggttaac
     7081 gttggcgaag aagaagagcg tcagatcgtt tgtggtgccc caaatgtgcg tgcaggcatc
     7141 aaggttatgg tggctcttcc gggagctcgt atcgctgaca attacaaaat caaaaaagga
     7201 aaaatccgtg gcttagagtc acttggaatg atctgttcac ttggtgaatt gggtatttct
     7261 gactcagttg tacctaagaa attcgcagat ggtattcaaa ttttgccaga aaatgccgtt
     7321 ccaggtgagg aagtcttttc atatctagac ttggatgatg aaatcatcga actttctatc
     7381 acaccaaacc gtgcagatgc cctttctatg cgtggagtgg ctcacgaagt ggcagccata
     7441 tatgacaagg cagtcaactt taaagaattt actttgacag aaacaaatga agctgcgaca
     7501 gatgcccttt ctgtgggcat tgagacagac aaggcgcctt actatgcagc tcgtatcttg
     7561 gacaatgtga ctatcgcacc aagtccacaa tggttgcaaa accttctcat gaacgaaggc
     7621 atccgtccca tcaataacgt tgtagacgtg acaaactaca tcctgctcta ctttggtcaa
     7681 cctatgcatg cttttgactt ggacacattt gaagggactg acatccgtgt gcgtgaagcg
     7741 cgtgctggtg aaaaattggt gaccttggac ggtgaagaac gtgacttgga cgtgaatgac
     7801 ctagtcatca ctgttgcaga caagccagta gcccttgcag gtgtcatggg tggtcaagca
     7861 acagaaatct ctgaaaaatc tagtcatgtt gtccttgaag ctgctgtttt caatggcaaa
     7921 tctatccgta agacaagtgg tcgcctgaac cttcgttctg agtcatcttc tcgctttgaa
     7981 aaaggaatta atgtggcaac agttaatgaa gcccttgatg cggcagctag cctgattgcg
     8041 gaacttgcag gtgcgacggt gcgtaagggt atcgtttcag cgggtgagct tgatacttca
     8101 gatgtagaag tttcttcaac tcttgctgat gttaaccgtg tcctcggaac tgagctgtct
     8161 tatgctgatg tcgaagacgt cttccgtcgt cttggctttg gtctttctgg aaatgcagac
     8221 agctttacag tcagcgtacc acgtcgtcgt tgggatatca caatcgaagc tgatctcttt
     8281 gaagaaatcg ctcgtatcta tggatatgac cgcttgccaa ccagccttcc aaaagacgat
     8341 ggtacagctg gtgaattgac tgtgacacaa aaactccgcc gtcaagttcg taccattgct
     8401 gaaggagcag gtttgacaga aatcatcacc tatgttctaa caactcctga aaaagcagtt
     8461 gagtttacgg ctcaaccaag taaccttacg gaactcatgt ggccaatgac tgtggatcgt
     8521 tcagtcctcc gtcaaaatat gatttcaggt atccttgata ccgttgccta caacgtggct
     8581 cgtaagaata aaaacttggc cctttacgag attggaaaag tctttgaaca aacaggtaat
     8641 ccaaaagaag aacttccaaa tgaaatcaac agttttgcct ttgccttgac aggcttggtt
     8701 gctgaaaaag atttccaaac agcagcagtt ccagttgatt tcttctatgc taaaggaatc
     8761 ctagaagcgc tctttactcg cttgggacta gaagtgacct atacagcaac agctgagatt
     8821 gccagccttc acccaggacg tacagcagtc atttcactcg gtgaccaagt tcttggtttt
     8881 cttggccaag tgcatccagt cactgctaag gcttacgata ttccagaaac gtatgtggct
     8941 gagctcaacc tttcagtcat cgaagctgcc cttcaacctg ctgctccatt tgtggaaatc
     9001 acgaaattcc cagcagtcag ccgtgacgtt gcccttctcc tcaaggcagc agtaactcac
     9061 caagaagtta tagatgctat ccaagctgcc ggcgtgaaac gtttgacaga tatcaaactc
     9121 tttgacgttt tctcaggtga gaaattggga cttggtatga agtcaatggc ttatagcttg
     9181 accttccaaa atccagaaga cagcttaacg gacgaagaag tcgcacgcta catggaaaaa
     9241 atccaagcat cgcttgaaaa aaaagtgaac gcagaagtgc gttaaacgat agtaggatac
     9301 aaattccccc tctagtttat gaacactaga ggggtgattt tatataatac tcaatgaaaa
     9361 tcaaaaagca aactaggaag ctagccgtaa gctgtacttg agtactgtaa ggcgaggctg
     9421 acgtggtttg aagagattgt cgaagagtat aaaataatta aaatgtgatt tctgtaaaaa
     9481 tacatctatg atcagagttt tgaaaactta caatgtctaa atctttaaca tagtagtggt
     9541 ttttaggcaa taaaatatga tctattgttg cattaaaaag ttttggactt tggctattcc
     9601 aagttcctct ttcaaaaggt ggtagtacat ttaatgcgtc cctatgagag cttatttttg
     9661 caagtgctcc atgacgcata gttgcattaa aatcatctgc aataatagcc tttggatatt
     9721 ttgaagccaa ttgattatga atgatgttta agtcttgctt ccagatttcc attaaacctg
     9781 gcagaggagg agcagtatgc aaggcaatga tatctggtat attttgtttt ctcgaatgta
     9841 atacaattgt cccgaaccgt gttgtatgaa aagttttagc ttctgtatag aaaccataac
     9901 ttttcttgac aatcacagtc acaggagcta ttccactatt ggtaggtgga gaagtgaaaa
     9961 tatcatagtt ggccatagaa agtccaactt gatgaaacaa tagtttgatt ctctggtttt
    10021 cttgctcacc tctgatattg gtagctagtt cagggaatat agccatatcg gcgtcaaaat
    10081 ggctaaaaat tcgctcaata tgttgtgctt ctatttgatt agcgacgttc caagttacta
    10141 attttaaggt tttagtctta tttgatgcag aagaaagggt tttatctgtt ccgaataata
    10201 gtaatatgag cgatagtaag agcaaaatgc cagagtaaaa ccgtatttgt ttatttttct
    10261 tgtaaaaaga tagggaaaaa aatacgaaac ttaaaatagc agccatagtt gcagtagcta
    10321 aggggaaggc ataaatctgt gccaagatag gtctggtaga tagccaaata ttaagattag
    10381 aagatggaaa aaaagaataa gttatgatag ggataacaaa gagaatgacc gaaagggcag
    10441 agagaaatgt tttaatcatt gtgtgagtac ctcaatttgc aatggttgct cggagctaat
    10501 gtgactttgt gactttactt gattgatatt ctttttcttg tcttcctcat agattaagta
    10561 caacccaagt aaaaaaagtc caatttaaga ttgaaatgat taaaaggcac agaaatgcaa
    10621 gacaattata ctacaaaagg caaacatttg acaatcgata gccgtcgctt aatcgaaaga
    10681 tggaaaaaag aagggaaatc aaatagagaa attgcctctc tgcttggaaa agttcctcaa
    10741 actatccaca ctgaaatcaa gcgt
//
LOCUS       DAVAZT010000066        10317 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVAZT010000066 DAVAZT010000000
VERSION     DAVAZT010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10317
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.066"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..125
                     /locus_tag="VQT45_001837"
     CDS             <1..125
                     /locus_tag="VQT45_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360110.1"
                     /translation="KASQWFKVSDKWYYVNGSGALAVNTTVDSYRVNANGEWVN"
     gene            complement(355..1335)
                     /gene="dusB"
                     /locus_tag="VQT45_001838"
     CDS             complement(355..1335)
                     /gene="dusB"
                     /locus_tag="VQT45_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HET2360111.1"
                     /translation="MTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(1322..2194)
                     /gene="hslO"
                     /locus_tag="VQT45_001839"
     CDS             complement(1322..2194)
                     /gene="hslO"
                     /locus_tag="VQT45_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HET2360112.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQERHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGAGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2359..3786
                     /locus_tag="VQT45_001840"
     CDS             2359..3786
                     /locus_tag="VQT45_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2360113.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLDSAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            3945..5453
                     /gene="glpK"
                     /locus_tag="VQT45_001841"
     CDS             3945..5453
                     /gene="glpK"
                     /locus_tag="VQT45_001841"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HET2360114.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            5495..7321
                     /gene="glpO"
                     /locus_tag="VQT45_001842"
     CDS             5495..7321
                     /gene="glpO"
                     /locus_tag="VQT45_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HET2360115.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKHLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPILDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            7391..8095
                     /locus_tag="VQT45_001843"
     CDS             7391..8095
                     /locus_tag="VQT45_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET2360116.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            8392..8595
                     /locus_tag="VQT45_001844"
     CDS             8392..8595
                     /locus_tag="VQT45_001844"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360117.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(8682..9269)
                     /locus_tag="VQT45_001845"
     CDS             complement(8682..9269)
                     /locus_tag="VQT45_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360118.1"
                     /translation="MFVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNILSDEVLE
                     VVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVNTIHGNKQ
                     ANTFANFMTGAGISYMIGRIGTLLGGPWGAIIGGAYFGIQAYQSYLDSQSPYPYYITS
                     TYIHVAQKKWKFITEYYRNSNYTGYVKTVTTYVNF"
BASE COUNT         3002 a         2041 c         2356 g         2918 t
ORIGIN      
        1 tgaaagcaag ccaatggttc aaagtatcag ataaatggta ctatgtcaat ggctcaggtg
       61 cccttgcagt caacacaact gtagatagct atagagtcaa tgccaatggt gaatgggtaa
      121 actaaaccta atataactag ttaatactga cttcctgtaa gaactcttta aagtattccc
      181 tacaaatacc atatcctttc agtagataat atacccttgt aggaagttta gataaaaaaa
      241 taactctgta atctctagcc ggatttatag cgctagagac tacggagttt ttttgatgag
      301 gaaagaatgg cggcattcaa gaggctcttt aagagagtta cgggttttaa actattaagc
      361 cttctccaat tgcaagaggg cttcaatctc tgccagggtg ctagcttgcg aaatggctcc
      421 acggagtttg gcagcgccag atgttccacg gagatagtga ggagcgaggc cgcggaattc
      481 acgaactgcg acgttttctc ctttgaggtt aatcaatcgt ttcaagtgtt cgtaggcgat
      541 cttcatcttg tcttcaaagg tcaaatcagg taggatttct cctgtttcaa agtaatggtt
      601 gatttggttg aagaggtaag gatttcccat ggcagctcgg ccaatcatga ctgcgtcagc
      661 accaacttct tcgatgcgtt gcttggcttc ttggacagta cggatatcac cgttggcgat
      721 gaatggaatc ttggttagag cttgggcaac cttgtaaagg gtctcaaggt ctgcgtggcc
      781 agtatacatt tgttcacggg tacggccatg catggcgagg gcagaaacac ctgcagcctc
      841 agcagcgagg gcattttcta ctgcaagaga tgggtccgcc catccggtac gcattttgac
      901 agtaagtggg atatcaagga cagactggac cttgttgatg atagagtaga tcttgtcagg
      961 atccttgagc cacatagctc cagcttcgtt cttcacgatt ttgttgacag ggcagcccat
     1021 gttgatatcg acgatatcgg tcttggtgtt ttcttggatg aattctgctg cgcgtgctag
     1081 gctgtcttca tcgctaccaa aaagttggat agagacaggg ttttcgccct catcgatatg
     1141 aagcatgtgc agggtttttt cgttgttgta ttggattccc ttgtcagaga ccatttccat
     1201 tacaacgagt ccagctccga gctcttttgc gatggtacga aaggctgagt tggtcacgcc
     1261 agccataggc gctaaaacgg tacgattggg aatctcaata ttgccaatca taaaaggtgt
     1321 attaagattt gtcacgaatg agttcctcca ggtccttttc atcaaagttg taagtagttt
     1381 ggcagaattg acaagtgatt tctgccccgt ggtcttcctc tttcatttcc tgtaagtctg
     1441 agcttggaag gctggcaaga gcgttcataa agcgttcatg gctacagtca cattggaaac
     1501 ggatttcttc ttcagaaaga cgcttgtagg cttcgtcccc gtagatagcc ttgaggaggg
     1561 cttcgatatg gtcgtcgctt tcgagaagag tagagatagc tggcatttct tggatgcgtt
     1621 tttcaaagcg agcaatctct tctttcttgg ctcctggcaa gacttgaact aggaaaccac
     1681 ctgcaacctt gaccttgtct tcctcgtcca aaaggacatt gaggccgacc gctgaaggcg
     1741 tttgttggct ttcagtaagg taaaaggcaa ggtcttcacc gatttctcca gagatgaggg
     1801 gagttataga gttgtaagga tttccagcac cgtagtctgt gataacgagg aattgaccat
     1861 ttccaacaaa aggtccgact aggacttcac cagtcgcagt ctttttgatg tcaacaccag
     1921 gattttgaac atagcctttg acgttcccct tggtatcagc gacggtgata atagcaccta
     1981 gagagctaga gcccaacacc ttaactgtaa gtttggtatt tcctttttca ttggctgcga
     2041 gaatctggct agcgataaga gttcgaccaa gcgctacagt tgagctagct tgggtttgat
     2101 gtctttcttg agcagtgcgg acggtttccg tgctatcaag gacaaaagca cgaaaggctc
     2161 cgctttctga tatagtttta ataattttat ccatagctac tattttagca taaaaatgcc
     2221 caaaggggga gccgtgtgtt tactgatttt caggataatg gaccaggaaa tcagcatgaa
     2281 aataaaaaga gaaacagatt atttcagcat ttgtaagatt tatgctatgc ttaaggtaga
     2341 aaatgaaagg ggtaacaaat gtatttagga gatttgatgg agaaagccga gtgtggtcaa
     2401 ttttcaatcc tttcctttct attacaagag tctcagacga ccgtcaaggc tgtaatggaa
     2461 gaaacaggat tttcaaaagc aaccctaacc aaatatgtca ccctgctcaa tgacaaggct
     2521 ttggatagtg gcttagaact gactattcac tcagaagatg aaaatctgcg tctgtctatc
     2581 ggtgcagcta ccaaggggag agatattcgg agcttgtttt tggatagtgc tgttaaatac
     2641 cagattttgg tttatcttct ctaccaccaa cagtttttag cccatcagct ggctcaagaa
     2701 ttggtgatta gcgaggctac gcttggtcgt cacttggctg gtttaaatca gattttgtca
     2761 gaatttgatt tatccatcca aaatggacgc tggagaggtc cagagcatca gattcgctat
     2821 ttctatttct gtcttttccg aaaggtctgg tcgagtcagg aatgggaagg tcacatgcag
     2881 aaaccagaga gaaaacagga gattgccaat ttagaggaaa tctgcggtgc aagtttgtct
     2941 gcggggcaga aattggactt ggttctctgg gctcacatca gtcaacaacg tcttcgggtc
     3001 aatgcttgtc agtttcaagt catagaagag aaaatgcgag ggtattttga caatatcttt
     3061 tatcttcgtt tgctgagaaa ggttccgtcc ttttttgctg ggcaacatat tccactagga
     3121 gttgaggatg gtgagatgat gatattcttc tcttttctcc tatctcatcg cattcttcct
     3181 cttcatacta tggagtatat tcttggtttt ggagggcagt tggcagattt actgacgcaa
     3241 ttgattcaag aaatgaagaa ggaggaacta ttgggggatt atacagagga ccatgtcacc
     3301 tatgaactca gtcagctttg tgctcaagtc tatctctata agggctatat tttacaggat
     3361 cgctacaagt accagttaga gaatcgtcat ccatatttac tgatggaaca tgattttaaa
     3421 gagacagcag aggagatttt tcatgctcta cctgcttttc aacaggggac agatttagat
     3481 aagaagattc tctgggaatg gctccagtta atcgaatata tggctgaaaa cggtggccag
     3541 catatgcgga ttggtctgga tttgacatct ggttttcttg tcttttcaag gatggcagcc
     3601 attttgaaac ggtatttgga atacaatcgt tttattacca ttgaagctta tgaccctagt
     3661 cggcattatg atttgctggt taccaataac ccgattcata agaaggaaca gacaccagtc
     3721 tattatttaa aaaacgactt ggatatggaa gatttggcag ggattcgtca gttattattc
     3781 acttaaaagg cttggttaat ctaggtcttt tttgtgaaat tcacacaatc tcctcacatt
     3841 tttttaaaaa ttaaaaaaag ttgataaaca agaaagcgct ttattttgta tactagtaag
     3901 tgtaaagagg aaacacctca agatctttat caggaggaca gtacatgtca caagaaaaat
     3961 acatcatggc cattgaccag ggaactacaa gttctcgtgc catcattttc aacaaaaaag
     4021 gggaaaaggt tagctcgagt caaaaagagt ttacccagat tttccctcag gcaggttggg
     4081 ttgagcacaa tgccaatgaa atttggaact ctgttcagtc agttattgcg ggtgctttca
     4141 tcgaaagtgg tgtcaagcca aatcaaatcg aggcaatcgg gattaccaac caacgtgaaa
     4201 caacggttgt ctgggataag aaaacaggac ttcctatcta caatgctatc gtttggcagt
     4261 cacgccagac agcacctttg gctgagcaac taaaaagcca aggttatgtg gaaaaattcc
     4321 atgaaaagac tggtttgatt attgatgctt acttctctgc taccaaggtt cgttggattt
     4381 tggatcatgt agaaggtgct caagagcgag cagaaaaagg ggaattgctc tttggtacta
     4441 tcgatacttg gttggtttgg aaattgactg acggtgcggc tcacgtgact gactactcaa
     4501 atgcagctcg taccatgctt tataacatta aagaactcaa atgggatgat gagattttgg
     4561 aaatccttaa cattccgaag gctatacttc cagaagttcg ttctaactcc gaaatctacg
     4621 gcaagacagc tccattccat ttctacggtg gagaggtgcc aatctcaggt atggctgggg
     4681 accaacaagc agccctcttt ggacagttgg cttttgagcc aggtatggtt aagaatactt
     4741 atggaacagg ctctttcatc atcatgaata ctggggaaga gatgcagttg tctgaaaaca
     4801 acctcttgac aaccattggt tacggaatca acggtaaggt ttattatgcc ttggaaggtt
     4861 ctatcttcat cgcaggaagt gctattcagt ggcttcgtga cggtcttcgc atggttgaaa
     4921 attcaccaga atctgaaaaa tacgctcgtg attctcacaa caacgatgaa gtttatgtcg
     4981 ttccagcctt tacaggtcta ggcgctccat actggaacca aaatgctcgt ggttccgtct
     5041 ttggtttgac tcgtggaaca agcaaagaag actttatcaa ggcgactttg caatctattg
     5101 cttatcaagt gcgtgatatc atcgacacca tgcaagtgga tactcagacc gccattcaag
     5161 tactgaaggt ggatggtggt gcagccatga acaacttcct catgcagttc caggcggata
     5221 ttttaggcat tgacattgca cgtgctaaaa acctggaaac aacagctcta ggagcggcct
     5281 tcctagcagg tttgtcagta gggtactgga aagacttgga cgagttgaaa ctcttgaacg
     5341 agacaggaga actctttgag ccatctatga acgaatctcg caaggaacaa ctctacaagg
     5401 gctggaagaa ggctgtgaaa gcaactcaag tctttgcgga agtagacgac taatactggc
     5461 agaataaagc gatttattta gaaagtgtgt aaatatggaa ttttcaaaga aaacacgtga
     5521 attgtcaatt aaaaaaatgc aggaacgcac cctggacctc ttgattatcg gtggaggaat
     5581 cacaggagct ggtgtagcct tgcaggcggc agctagcggt cttgagactg gtttgattga
     5641 aatgcaagac tttgcagaag gaacatctag tcgttcaaca aaattggttc acggaggact
     5701 tcgttacctt aaacaattcg acgtagaagt ggtctcagat acggtttctg aacgtgcagt
     5761 ggttcaacaa atcgctccac acattccaaa accagaccca atgctcttac cagtttacga
     5821 tgaagatgga gcaaccttta gcctcttccg tcttaaagta gccatggact tgtacgacct
     5881 cttggcaggt gttagcaaca caccaactgc gaacaaggtt ttgagcaagg atcaagtctt
     5941 ggaacgccag ccaaacttga agaaggaagg cttggtagga ggtggagtgt atcttgactt
     6001 ccgtaacaac gatgcgcgtc tcgtgattga aaacatcaaa cgtgccaacc aagacggtgc
     6061 cctcattgcc aaccacgtga aggcagaagg cttcctcttt gacgaaagtg gcaagattac
     6121 aggtgttgta gctcgtgatc tcttgacaga ccaagtattt gaaatcaagg cccgtctggt
     6181 tattaataca acaggtcctt ggagtgataa agtacgtaat ttgtctaata agggaacgca
     6241 attctcacaa atgcgcccaa ctaagggagt tcacttggta gtggattcaa gcaaaatcaa
     6301 ggtttcacag ccagtttact ttgacacagg tttgggtgac ggtcgtatgg tctttgttct
     6361 cccacgtgaa aacaagactt actttggtac aactgataca gactacacag gtgatttgga
     6421 gcatccaaaa gtaactcaag aagatgtaga ttatctactt ggcattgtca acaaccgctt
     6481 tccagaatcc aacatcacca ttgatgatat cgaaagcagc tgggcaggtc ttcgtccatt
     6541 gattgcaggg aacagtgcct ctgactataa tggtggaaat aacggtacca tcagtgatga
     6601 aagctttgac aacttgattg cgactgttga atcttatctc tccaaagaaa aaacacgtga
     6661 agatgttgag tctgctgtca gcaagcttga aagtagcaca tctgagaaac atttggatcc
     6721 atctgcagtt tctcgtgggt ctagcttgga ccgtgatgac aatggtcttt tgactcttgc
     6781 tggcggtaaa atcacagact accgtaagat ggctgaagga gctatggagc gcgtggttga
     6841 catcctcaaa gcagaatttg accgtagctt taaattgatc aattctaaaa cttaccctgt
     6901 ttcaggtgga gaattgaacc cagcaaatgt ggattcagaa atcgaagcct ttgcgcaact
     6961 tggagtatca cgtggtttgg atagcaagga agctcactat ctggcaaatc tttacggttc
     7021 aaatgcaccg aaagtctttg cacttgctca cagcttggaa caagcgccag gactcagctt
     7081 ggcagatact ttgtcccttc actatgcaat gcgcaacgag ttggctctta gcccagttga
     7141 cttccttctt cgtcgtacca accatatgct ctttatgcgt gatagcttgg atagcatcgt
     7201 tgagccaatt ttggatgaaa tgggacgatt ctatgactgg acagaagaag aaaaagcaac
     7261 ttaccgtgct gatgtcgaag cagctctcgc taacaacgat ttagcagaat taaaaaatta
     7321 agaaaaaata aaagaggtgg agggcagcat tccttgtcgc ccgtcccttc tttttaatgg
     7381 agacagaaag atgatgaatg aattatttgg agaatttcta gggactttaa tcctgattct
     7441 tctaggaaat ggtgttgttg caggtgtggt tcttcctaaa accaagagca atagctcagg
     7501 ttggattgtg attactatgg gttgggggat tgcagttgcg gttgcagtct ttgtatctgg
     7561 caagctcagt ccagctcatt taaacccagc tgtgaccatc ggtgtggcct taaaaggtgg
     7621 tttgccttgg gcttccgttt tgccttatat cttagcccag ttcgcagggg ccatgctggg
     7681 tcagattttg gtttggttgc aattcaaacc tcactatgag gcagaagaaa atgcaggcaa
     7741 tatcctggca accttcagta ctggaccagc catcaaggat actgtatcaa acttgattag
     7801 cgaaatcctt ggaacctttg ttttggtgtt gacaatcttt gctttgggtc tttacgattt
     7861 tcaggcaggt atcggaacct ttgcagtggg aactttgatt gtcggtatcg gtctatcact
     7921 aggtgggaca acaggttatg ccttgaaccc agctcgtgac cttggacctc gtatcatgca
     7981 cagcatcttg ccaattccaa acaagggaga cggagactgg tcttacgctt ggattcctgt
     8041 tgtaggccct gttatcggag cagccttggc agtgcttgta ttctcacttt tctagtttat
     8101 actcttcgaa aatcaaattc aaaccacgtc agcgtcgcct taccgtactc aagtacagct
     8161 tacggctagc ttcctagttt gctctttgat tttcattgag tattagaaaa caattatgtt
     8221 gatagagctt gggcaagagc ccaatttcag caaaaaatga agtaaatctt ctcataataa
     8281 aacgcatcat atcaagcacg aaaattccac gaggtcaact acagtcagaa agctgaacaa
     8341 caagccaaaa cgcccaaaaa aggcggcaaa aagcaagcac ctgcaagcaa cgtgccgaaa
     8401 tggtcaaatc ctgattatgt caacgaatta gacccaaaaa tcgttgatat gctagtagaa
     8461 tttcacaagt cacaaggcac tttggaaact cccgaggcgc aagcagaaat cgcccaaaaa
     8521 cgtgaagaaa tcgagcaaag gagagctgag cttgaggata aaaaacaaga gcttttgaac
     8581 cgcttgaaca aatagagttt cgcaagtatt atgcttacaa attacttgag caattaacta
     8641 aaatataaac cctgccttta tatctaggca gggtttatat tttagaaatt cacgtaggtt
     8701 gttacggttt ttacataccc agtatagttt gagtttctat agtattcagt gataaacttc
     8761 catttttttt gagcaacatg gatataagta cttgttatgt agtatggata tgggctttgt
     8821 gaatccaagt aagactgata agcttgtata ccaaaatatg ctccaccaat tattgcaccc
     8881 catggacccc ccaataaagt acctatccta ccaatcatat aactgattcc agcaccagtc
     8941 atgaagttag cgaatgtgtt agcttgttta ttcccatgta ttgtgttgac gtaattccaa
     9001 acattaggat cgtatgatct aaaagatata tttaggtcga tttcattctt ttgataagcc
     9061 atataaaatg ccccattgat atagacgccg tcagcacgtc gttcaatagt gtctacactt
     9121 ccatctggat tgacaacctc aagaacttca tcgcttaaaa tatttacttg cgtatctccg
     9181 aaccgcactg atgagccatt ctcaaactga gcctcaccag atacaacttt agagtttgcc
     9241 gataagctat catcagcaaa aacaaacaag cgacggggaa atgctagaca tacagaaaac
     9301 agacataact agcaaacaca tgcatttaaa catcttagac ataacggaaa ctcctttgta
     9361 tttttgattt ttttcaactt ttattataca ataaaaccaa ataaaaagaa agcggtaaca
     9421 atatgcttaa tgcgaaaatt ttttatatat ttttatgttt gatcgttatc gaaactacag
     9481 gcttgttgtt gttgaaaaga ggtctcgaaa tgggttattt agacacagaa gctattatcc
     9541 tcgcagtttt ttcatttgct ttttacaacc tatgttcatt cgcttgggtc tgctctacaa
     9601 taaaaaacaa taaaaaataa atagacgtat tttcaaaaaa aaaaaaaaaa aatgcatatt
     9661 tatcttagca aaacgacaat ttaaatcgtc gtttttttgt agtacgacgg gcatgtcgta
     9721 tatctgaggt gtaagtcctc ggtgggcacc tgctaccggt gaacccaata gcgattccca
     9781 agcctgacta tcgtgaggta gcagggagag gaagggatag cgaaatcgtg gctctacgaa
     9841 caggaacgtg atagtaaggc gtatatagcg gataaggagg cttcaaactc taaagtccaa
     9901 aaaggtagtc gtaacctata tgtgtaaatc acgagagtaa ttgaattcgg actaaggttt
     9961 gtgtgaaaaa gataaatctt tctagagtct aaagactctg cgtcagattt cctattttca
    10021 ctgtaacctt ttaacgtcct catatcttgt ataaacgagg aaagatgtac gacttatccc
    10081 gtgaggtttc atgagcgctg aaagcgtagt aacaacgaat catgagaagt cagccgagcc
    10141 catagtagtg aggaaacttc cgtaatggaa gtggagcgaa ggggtgaata ctcaaacagt
    10201 ctggggagag actgtttgag gtctgtcgct agaaagagaa aacgacagat cgaagtaatc
    10261 ctacttcact tgtgtctgta aaatgagtgg tctgatagaa ctggactttg acacgta
//
LOCUS       DAVAZT010000067        10086 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVAZT010000067 DAVAZT010000000
VERSION     DAVAZT010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10086
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.067"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            588..986
                     /locus_tag="VQT45_001846"
     CDS             588..986
                     /locus_tag="VQT45_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET2360119.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEVGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKKQTVFLILQQ"
     gene            1024..1713
                     /locus_tag="VQT45_001847"
     CDS             1024..1713
                     /locus_tag="VQT45_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2360120.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNFV
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            1755..2003
                     /locus_tag="VQT45_001848"
     CDS             1755..2003
                     /locus_tag="VQT45_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360121.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLKWFVLERLELKDDA"
     gene            2033..2644
                     /locus_tag="VQT45_001849"
     CDS             2033..2644
                     /locus_tag="VQT45_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2360122.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            2805..3599
                     /locus_tag="VQT45_001850"
     CDS             2805..3599
                     /locus_tag="VQT45_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HET2360123.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            3596..4231
                     /gene="trmB"
                     /locus_tag="VQT45_001851"
     CDS             3596..4231
                     /gene="trmB"
                     /locus_tag="VQT45_001851"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HET2360124.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            4357..4836
                     /gene="rimP"
                     /locus_tag="VQT45_001852"
     CDS             4357..4836
                     /gene="rimP"
                     /locus_tag="VQT45_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HET2360125.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            4880..6016
                     /gene="nusA"
                     /locus_tag="VQT45_001853"
     CDS             4880..6016
                     /gene="nusA"
                     /locus_tag="VQT45_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HET2360126.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            6038..6331
                     /locus_tag="VQT45_001854"
     CDS             6038..6331
                     /locus_tag="VQT45_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HET2360127.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            6324..6623
                     /locus_tag="VQT45_001855"
     CDS             6324..6623
                     /locus_tag="VQT45_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HET2360128.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            6640..9432
                     /gene="infB"
                     /locus_tag="VQT45_001856"
     CDS             6640..9432
                     /gene="infB"
                     /locus_tag="VQT45_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HET2360129.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     VKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            9683..10033
                     /gene="rbfA"
                     /locus_tag="VQT45_001857"
     CDS             9683..10033
                     /gene="rbfA"
                     /locus_tag="VQT45_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HET2360130.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
BASE COUNT         3060 a         1847 c         2301 g         2878 t
ORIGIN      
        1 attcaagatt tggatgaaaa attttaaaaa acaatgatat actaaacttg tcaaagttgc
       61 aacgggtgct gctacattat gttaaaaatc gctcttgatt gataagctgg atttgttagg
      121 aaaggagtaa ataattatgg ataagaaaaa gatagtttcg actataatat gtatagtatt
      181 tcttgtagtg tcagtagata atttttttag agacttaacc ccgttactgt tcattttaaa
      241 tattattggc ctgtcttgct tttcagtgct aacatacatt aacataaaag agatactctt
      301 aaatataagt aaatgatgat ttggttagtc ctagaaccaa tcaacttatg tttatcggct
      361 tggcagattt tatgtttgtc atttgtttgt atagaggtat ttcagaaaca gaattctatc
      421 aacaactaat cgcttatata ggtgtattct ctgcttgttt atcacgcttc tgctcatgtg
      481 gggcttgaag tattataaaa agtagctttc tatccttttc tgacaggata tttgagtaga
      541 aggctctatt aaattgttag tgaaataaat gaatggaggt atttaatatg aaatacagat
      601 tattttttgt tattttcttg agtagtgtgt tggatattct tttagggaca tttttacaaa
      661 tctctatcgt atctattggg tggcttgttc tttacagtgg tttgtttgaa gtaggagttt
      721 tccttcttgc taataaaggg gtggcggtaa aaatcaagga agtagatatt cgaaatcgct
      781 ttaaatttat ttttggaaaa accttatggt ttcaaattct tttgctcatc tttttgataa
      841 tcaaacttta tcttggtttg gatgcgaggt tgattttatt ctatggacat attttcattg
      901 tctttaatgc cttaatgtat ctattatcta gtagtcaggt tagccttaaa aaaaaacaaa
      961 ctgtcttctt aatcttacag cagtagagtc tgacaaggtg aggtcatagt agggaggatt
     1021 tctatgaaaa agtatcaact tctattcaaa ataagtgcag tcttctctta cttatttttc
     1081 gtatttggtc tttctcagct gacgcttatc gtccaaaatt attggcaatt ttcttcccag
     1141 attggtaatt tcgtctggat tcaaaatatc ttgagtttac tttttattgg agtcatgatt
     1201 gtggttcttg ttaagacagg ccatggttat ctcttccgca ttccaagaaa aaaatggctt
     1261 tggtattcga ttttgacagt attagtggta gtgttccaga tctcttttaa cgttcagaca
     1321 gctaaacatg ttcagtcaac tgcggaaggt tgggctgtat tgattggtta tagtgggact
     1381 aactttgcag agctaggtat ttatatagcc ctgttctttc tggttccact gatggaagaa
     1441 ttgatttata gaggattact gcaacatgct ttctttaagc attcgcgatt tggtcttgat
     1501 ttgcttcttc cttctatttt atttgctctc cctcattttt caagcctgcc tagtctgtta
     1561 gatatcttcg tctttgcaac agttggaatc atctttgctg gtttgacccg ctataccaag
     1621 agcatttatc catcctatgc ggtgcatgtg atcaataata ttgtagcgac cttcccgttt
     1681 ttgctcactt ttctacatag ggtcttgggg taaaaaaaca aaaggcttgc ttttcagcca
     1741 tagaggaggt catcatgtat aaacacttat ttttcctaga ttccaaaact ttagatcggt
     1801 tgacacccta tattctagtc ttggcttctg acaccattgc ttttaatgtt tttgtgctaa
     1861 cctttgtatc tgcggtggtt tttaatttcc taaattccat gctagcttta atggctatat
     1921 tcataggggc tggctatgtg gtcggatttt ggttgctaaa atggtttgtt ttggaaaggt
     1981 tagagctaaa ggatgacgcg taggaagtct gtttggtgag gaggatagtt ttatggagtt
     2041 ttttgataaa tttcatgcct tgtgttttgg atttttagta ctaataattg tcattacagt
     2101 tccttatacg attaaccatg ggggtttttt tcaaaatgaa tctgcattga ttcttgtaag
     2161 tcttcttgta acctcgctga gtgttgctta tgctagaaag tttgaaatga tttcttttgg
     2221 gatgttaagc aagaaacaac ttttgctttt cattgcaatc tttcttctaa gtgtacttga
     2281 gacgctggtt tatattcatt tcttcgctgt ttcttctggc tcaggggtcc aacacttggc
     2341 ggaagtcagc agaggaattt ccctgtcttt gattttgact acctcagttt ttggccccat
     2401 ccaggaggaa ctcattttca gaggacttct tcaaggtgcg gtttttgaca attcttggtt
     2461 agggcttgtg ctaacttcct ctctcttttc tttcatgcat ggaccttcta atgtcccttc
     2521 gtttattttt tatctacttg ggggtttgtt gctgggcttt gcttataaaa agagtcaaaa
     2581 cctatgggtt tctactctag tacacatgtt ttacaacagt tggccactcc tatattattt
     2641 ataaaaatta tgaaaaggta agcagaagac ggtgcttacc tttttcaagc tataatgata
     2701 cccaagccaa tccagaggct tttctttgag aatcgggtta gagtggttga cgaataggcc
     2761 aaaaactagt agaatagtaa ggaaacttta tacggaggaa agaaatggat ttgggtgata
     2821 atgagctaac actgactccc atacctggga aaagtggcaa ggcttatatg ggtagctatc
     2881 ctgacgggaa gcgcatcttt gtaaaaatga acacctctcc aatcctacct ggtctagcta
     2941 gagaacaaat tgctccacaa ttattatgga gtcgtcgttt ggcagatggg cgtgatatgt
     3001 gtgctcaaga atggttgaca ggcaagatat tgacccccta tgatatgaat cgtaagcaaa
     3061 tcgtcaatat tttaacccgt cttcatcgct cacgtccgtt gatgacacaa ttgagtcgtt
     3121 tgggctatgc catggaaaca cctgtagatt tactacagtc ttggcaggaa acggctccag
     3181 atgctttgcg taaaaatcat tttatcagtg aagtgatggc tgatttacgt cagactattc
     3241 caggatttag agaggaccat gcgaccattg tccatggaga tgtacgacat agtaattgga
     3301 ttgagacaga tagtggcttg atttatttag tagattggga ttcggttcgc ttgaccgatc
     3361 gcatgtttga tgtggcccat atgctctgcc attatatttc agaacatcag tggaaggaat
     3421 ggttgaccta ctacggttac aagtacaatc aaacggtatt aagtaaattg tattggtatg
     3481 gtcaattgtc ttatttgagt cagatttcca agtattatat gaaccaagat ttagaaaatg
     3541 tcaatcggga gattcatggt ttgcgtcatt tccgagacaa gtatggaaag agaagatgag
     3601 agttagaaat cgtaaagggg caacagaatt actagaggca aatccccagt atgtggtcct
     3661 caatcccttg gaagccaagg caaaatggcg ggacttgttt ggcaatgata atcccattca
     3721 tgtggaagtt ggaagtggaa agggtgcctt tgtttcaggt atggccaagc aaaaccctga
     3781 catcaactat atcgggattg atattcaaaa gtctgttttg agctacgctt tggacaaggt
     3841 gcttgaagtt ggagtgccta acatcaagct cttgtgggta gatggttctg acttaactga
     3901 ctattttgaa gacggtgaga ttgatcgctt gtatctgaac ttttcagatc catggccgaa
     3961 aaaacgccat gaaaagcgtc gtttgaccta caagaccttc ttggatacct tcaaacgtat
     4021 cttgcctgaa aatggagaaa ttcatttcaa gacggataac cgtggcttgt ttgagtacag
     4081 tttagtgagc ttttctcaat atggcatgaa actcaatggt gtctggttag atttgcatgc
     4141 cagtgatttt gaaggcaatg tcatgacaga atacgagcaa aaattctcaa acaaggggca
     4201 agttatctac cgagttgagg cagaatttta agagatagcc taaaattagg ctgtacaagt
     4261 gcttttgctt tacataagtt ggcaaacgtg ctatactgat agtaagaata tgaaaagtga
     4321 ggcggggaaa tatcttcgcc tcttgcttat gaggaggtgg acgcaatcgc aacaatcgta
     4381 gaattagtca gagaagttgt agaacctgtc atagaagctc cttttgaact cgtggatatc
     4441 gagtatggaa agattggcag tgacatgatt ctcagtattt ttgtagataa acccgaagga
     4501 attaccttga acgacacggc agacttgaca gaaattatca gtcctgtcct agacaccatc
     4561 aagccagatc ccttcccaga acaatatttc ctagaaatta ccagtccagg tttggaacgc
     4621 cctttgaaaa ccaaggatgc cgtcgctgga gcggttggaa aatacatcca tgtcgggctc
     4681 taccaagcca tcgataagca aaaggtcttt gaaggaacct tgttggcctt cgaagaggac
     4741 gagttgacta tggaatatat ggacaagacg cgtaagaaaa ccgtccaaat tccatacagt
     4801 ttagtatcaa aagcacgttt agcagttaaa ttatagaaaa agaaaggata gcttttgagg
     4861 attcaaaagt gaagaaaaca tgagtaaaga aatgctagag gccttccgca ttttggaaga
     4921 agacaaggga atcaaaaaag aagatatcat cgacgcagta gtagagtcgc ttcgttccgc
     4981 ttatcgcaga cgctatggtc agtcagacag cgtagctatt gacttcaacg aaaaaacagg
     5041 tgactttaca gtttatactg tccgtgaagt tgttgatgaa gtatttgata gccgtttgga
     5101 aatcagcttg aaagatgctc ttgccattaa ttcagcttat gaacttggag acaaaatcaa
     5161 gtttgaagaa gcaccagctg agtttggtcg tgtagcagcc cagtctgcca aacaaaccat
     5221 catggaaaaa atgcgcaagc aaacacgtgc catcacttac aatacttaca aagaacatga
     5281 gcaagaaatc atgtctggta cagtagaacg ctttgacaac cgctttatct atgtcaacct
     5341 tggtagcatc gaagcccaat tgtcaaaaca agaccaaatt cctggagaag tttttgcttc
     5401 tcatgatcgt atcgaagttt atgtttacaa ggttgaagac aaccctcgtg gtgtgaacgt
     5461 ctttgttagc cgtagtcatc cagaaatgat caaacgttta atggagcaag aaattccaga
     5521 agtttatgat ggaactgttg aaatcatgag cgtggctcgt gaagcaggtg accgtacgaa
     5581 ggttgctgtt cgtagccaca atccaaacgt ggatgctatc ggtacaatcg ttggacgtgg
     5641 tggtgctaat atcaagaaga ttactagcaa attccaccca gctcgttacg atgctaaaaa
     5701 tgaccgcatg gtaccaatcg aagaaaatat cgatgttatc gagtgggtag cagatccagc
     5761 tgaatttatc tacaatgcca tcgctcctgc tgaggttgac caagttatct ttgatgaaaa
     5821 cgacagcaaa cgtgccttgg tggttgttcc agataacaag ctttctcttg ccattggtcg
     5881 tcgtggacaa aacgtgcgct tggcggctca cttgactggt taccgtatcg atatcaagtc
     5941 tgctagcgaa tttgaagcca tggaagacgc tgcttcagta gagttggaag tagaaaacga
     6001 tactgtagaa gaataaaagc tgctagagga gggaaagatg aaaacaagaa aaatcccttt
     6061 gcgcaagtct gttgtgtcta acgaagtcat tgataagcgt gatttgctcc gcattgtcaa
     6121 gaacaaggaa ggacaagtct ttattgatcc tacgggcaag gccaatggcc gcggcgctta
     6181 tatcaaacta gacaatgcag aagccctaga ggcgaaaaag aagaaggtct ttaaccgcag
     6241 ctttagcatg gaagtggaag aaagctttta tgacgagttg atcgcttatg tggatcacaa
     6301 agtgaaaaga agagagttgg gacttgaata agcaaaagat aagtaatctc ttggggcttg
     6361 ctcagcgagc agggcgcatc atatcgggtg aagaattggt ggtcaaggcc attcaagacg
     6421 gcaaggccaa gttggtcttt ctagctcatg atgctggacc caatctgacc aagaagattc
     6481 aagataaaag tcattattat caagtagaaa ttgtaaccgt gttttcaaca ctggaattaa
     6541 gcatagcagt cgggaaatcg agaaaggttt tggctgtaac agatgctgga tttacaaaga
     6601 aaatgaggtc tcttatggaa tagaagagga ggacatgatt tgtctaagaa aagattgtac
     6661 gaaatcgcaa aagaacttgg aaaagaaagt aaagaagttg tagcgcgtgc aaaagagttg
     6721 ggcttggatg tgaaaagcca ctcatcaagt gtggaagaag ctgtcgctgc aaaaattgct
     6781 gccagcttta agcctgcagc tgctccgaaa gtagaagcaa aacctgcagc accaaaagta
     6841 agtgcagaaa agaaagccga aaaatctgag ccagctaaac cagctgtagc taaggaagag
     6901 gcaaaaccgg ctgagccagt tgctccgaaa acagaaaaag tagcagtgaa accgcaaagt
     6961 cgtaatttca aggctgagcg tgaagcccgt gctaaagagc aggcagaacg acgcaagcaa
     7021 aataagggca ataaccgtga ccaacaacaa aacggaaacc gtcagaaaaa cgacggccgt
     7081 aatggtggaa aacaaggtca aagcaaccgc gacaatcgtc gctttaatga ccaagctaag
     7141 aagcagcaag gtcagcaaaa acgtagaaat gagcgccgtc agcaagagga taaacgttca
     7201 aatcaagcgg ctccacgtat tgactttaaa gcccgtgcag cagccctaaa agcagagcaa
     7261 aatgcagagt acgctcgttc aagtgaggaa cgcttcaagc agtatcaggc tgctaaagaa
     7321 gccttggctc aagctaacaa acgcaaggaa ccagaggaaa tctttgaaga agcggctaag
     7381 ttagctgaac aagcacagca agttcaagca gtggttgaag tcgtccctga gaaaaaagaa
     7441 cctgcagtgg atacacgtcg taaaaaacaa gctcgaccag acaaaaatcg tgacgattat
     7501 gatcatgaag aagatggtcc tagaaaacaa caaaagaatc gaagtagtca aaatcaagtg
     7561 agaaatcaaa agaatagtaa ctggaataac aacaaaaaga acaaaaaagg caataacaag
     7621 aacaaccgta atcagactcc aaaacctgtt acggagcgta aattccatga attgccaaca
     7681 gaatttgaat atacagatgg tatgaccgtt gcggaaatcg caaaacgtat caaacgtgaa
     7741 ccagctgaaa tcgttaagaa acttttcatg atgggtgtca tggccacaca aaaccaatcc
     7801 ttggatgggg aaacaattga actcctcatg gtggattacg gtatcgaagc caaacaaaag
     7861 gttgaagtgg ataatgctga catcgaacgt ttctttgtcg aagatggtta tctcaatgaa
     7921 gatgaattgg ttgagcgtcc accagttgtt actatcatgg gacacgttga ccacggtaaa
     7981 acaacccttt tggatactct tcgtaactca cgtgttgcga caggtgaagc aggtggtatt
     8041 actcagcata tcggtgccta ccaaatcgtg gaaaatggta agaagattac cttccttgat
     8101 acaccaggac acgcggcctt tacatcaatg cgtgcgcgtg gtgcttctgt taccgatatt
     8161 acgatcttgg tcgtagcggc agatgacggg gttatgcctc agactattga agccatcaac
     8221 cactcaaaag cagctaacgt tccaatcatc gtagccatta acaagattga taaaccaggt
     8281 gctaacccag aacgcgttat cggtgaattg gcagagcatg gtgtgatgtc aaccgcttgg
     8341 ggtggagatt ctgaatttgt tgaaatctca gctaaattca accaaaatat cgaagaattg
     8401 ttggaaacag tccttcttgt agctgaaatc caagaactca aggcagaccc aacagtgcgt
     8461 gcaatcggta cggttatcga agcgcgcttg gataaaggaa aaggtgcggt cgcaaccctt
     8521 cttgtacaac aaggtacctt gaatgttcaa gacccaatcg ttgtcggaaa taccttcggt
     8581 cgtgtccgtg ctatgaccaa cgaccttggt cgtcgtgtta aagttgctgg accatcaaca
     8641 ccagtctcta tcacaggttt gaacgaagca ccgatggcgg gtgaccactt tgccgtttac
     8701 gaggatgaaa aatctgcgcg tgcagcaggt gaagagcgtg ccaaacgtgc cctcatgaaa
     8761 caacgtcaag ctacccaacg tgttagcctt gaaaacctct ttgataccct taaagctggg
     8821 gaactcaaat ctgttaatgt tatcatcaag gctgatgtac aaggttctgt tgaagccctt
     8881 tctgcctcac ttcaaaagat tgacgtggaa ggtgtcaaag tgactatcgt ccactcagcg
     8941 gtcggtgcta tcaacgaatc agacgtgacc cttgccgaag cttcaaatgc ctttatcgtt
     9001 ggtttcaacg tacgccctac accacaagct cgtcaacaag cagaagctga cgatgtggaa
     9061 atccgtcttc acagcattat ctacaaggtt atcgaagaga tggaagaagc tatgaaaggg
     9121 atgcttgatc cagaatttga agaaaaagtt attggtgaag cggttatccg tgaaaccttc
     9181 aaggtgtcta aagtgggaac tatcggtgga tttatggtta tcaacggtaa ggttgcccgt
     9241 gactctaaag tccgtgttat ccgtgatggt gtcgttatct atgatggtga actcgcaagc
     9301 ttgaaacact ataaagacga cgttaaggaa gttacaaacg gccgtgaagg tggattgatg
     9361 atcgacggct acaatgatat taagatggat gatgtgattg aggcgtatgt catggaagaa
     9421 atcaagagat aagatttttt gctcctttct taggtggtga gggacgcaag caaaccgatg
     9481 gtttcattgc ttatttttga gcctagggtc tcaaaaatcc cctgtgatgg gactgataaa
     9541 tcagttccat cactttcacc acggcgaaag aagcagatga cttcaaattg aacttcgttt
     9601 caatttaaac tgaaaatcaa gaagtttaaa atagctaggt ctgctggcct agcttttggt
     9661 tcaaagtaga gaaaggaata tcatggcaaa tcatttccgt acagatcgtg tgggcatgga
     9721 aatcaagcgt gaagtcaatg agattttgca aaagaaagtc cgtgatccac gtgtccaagg
     9781 tgtgaccatc acagatgttc agatgctggg tgacttgtct gttgccaagg tttattacac
     9841 cattttgagt aaccttgctt cggataacca aaaagcccaa atcgggcttg aaaaagcaac
     9901 tggtaccatc aaacgtgaac ttggtcgcaa tttgaaattg tacaaaatcc cagatttgac
     9961 cttcgtcaaa gacgagtcca tcgagtatgg aaacaagatt gacgagatgc tacgcaatct
    10021 ggataagaac taaagaagag gggttgcccc tctttttcgg ctctttgtca actgtagtgg
    10081 gttgaa
//
LOCUS       DAVAZT010000068        10046 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVAZT010000068 DAVAZT010000000
VERSION     DAVAZT010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10046)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10046
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.068"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(104..1807)
                     /gene="ilvD"
                     /locus_tag="VQT45_001858"
     CDS             complement(104..1807)
                     /gene="ilvD"
                     /locus_tag="VQT45_001858"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HET2360131.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(2040..2972)
                     /locus_tag="VQT45_001859"
     CDS             complement(2040..2972)
                     /locus_tag="VQT45_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HET2360132.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATNNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(2969..3826)
                     /locus_tag="VQT45_001860"
     CDS             complement(2969..3826)
                     /locus_tag="VQT45_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET2360133.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(3830..5176)
                     /locus_tag="VQT45_001861"
     CDS             complement(3830..5176)
                     /locus_tag="VQT45_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET2360134.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMVIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSATEE"
     gene            complement(5189..5473)
                     /locus_tag="VQT45_001862"
     CDS             complement(5189..5473)
                     /locus_tag="VQT45_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2360135.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(5477..7507)
                     /locus_tag="VQT45_001863"
     CDS             complement(5477..7507)
                     /locus_tag="VQT45_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HET2360136.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NSHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            7699..8706
                     /locus_tag="VQT45_001864"
     CDS             7699..8706
                     /locus_tag="VQT45_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET2360137.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            8709..8909
                     /locus_tag="VQT45_001865"
     CDS             8709..8909
                     /locus_tag="VQT45_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET2360138.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            9061..9243
                     /gene="rpmF"
                     /locus_tag="VQT45_001866"
     CDS             9061..9243
                     /gene="rpmF"
                     /locus_tag="VQT45_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HET2360139.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKITKAASAE"
     gene            9259..9408
                     /gene="rpmG"
                     /locus_tag="VQT45_001867"
     CDS             9259..9408
                     /gene="rpmG"
                     /locus_tag="VQT45_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET2360140.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(9900..>10046)
                     /locus_tag="VQT45_001868"
     CDS             complement(9900..>10046)
                     /locus_tag="VQT45_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET2360141.1"
                     /translation="YLNESGSMATGWVTVSGKWYYTYNSGDLLVNTTTPDGYRVNANG
                     EWVG"
BASE COUNT         3256 a         2133 c         1627 g         3030 t
ORIGIN      
        1 ccaaaacact gttttgaggt tgtggataga actgacgaag tcagtaacca tacctacggc
       61 aaggcgacgt tgacgtgatt tgaagagatt ttcgagtatg agtttatttt ttacctgact
      121 tgtccatatt ccagaagtct gtcacggctc cgcgtgaagc agatgatacg atgtgggcat
      181 atttaccgag gacaccacgg ctgtaaagtg gtggcaaggt tgtttctgcc ttgcgttttt
      241 caagttcttc ttcggatacg gccatagaaa tttctttggt atcttggtca accgtaacga
      301 tatcgccggt acggagatag gcaattggtc caccatcctg agcttcagga gcgatatgtc
      361 caacaaccag accataagta ccaccagaga aacgtccgtc cgtcaagagg gccaccttat
      421 ctccctgacc tttaccaaca atcattgaag aaagtgatag catctcaggc ataccaggac
      481 cacctttagg tccaacaaaa cgaacaacga ctacatcgcc atcaacgatt tcatctgtca
      541 gaacggcctg aatcgcatct tcttctgagt caaagacctt agctggccca acgtgacgac
      601 gcactttaac acctgatacc ttggcaactg caccgtcagg agcaaggttc ccgttcaaga
      661 tgataagcgg accatccgca cgttttggat tttcaagtgg catgataact ttttggcctg
      721 gagtcaagtc tgcaaagtca gccaagtttt cagctacagt cttaccagta catgtgatgc
      781 gatctccgtg aaggaaacca tttgccaaca aatacttcat aaccgcaggg acaccaccga
      841 cttcgtagag gtcttggaag acatactgac cagatggttt caagtcggcc aagtgaggca
      901 cacgttcttg aatcgtattg aagtcctcaa gtgacaagtc aacatttgcg gcatgggcaa
      961 tggcgagcaa gtgaagagtg gcgtttgtag aaccaccgag agccatcgtt acagtgatag
     1021 catcttcaaa ggcttcacga gtcaagatat ctgatggttt gagaccaagt tccaacatct
     1081 taacaacagc acgtcctgct gcttcgatat cttctttctt atcagctgat tcagctgggt
     1141 gagaggatga ccctggcaaa ctcatcccta gaacttcgat agcagttgcc atggtattag
     1201 cagtatacat accaccacaa ccaccagggc cagggcaggc attacattca agacgtttca
     1261 cgtcctcagc tgtcatgtca ccgtggttcc attttccgat accttcaaag acagaaacca
     1321 agtcgatatc tttaccatca agatttcccg gtgcaatagt tccaccatag gcgaaaatag
     1381 ctgggatatc catattagca atagcaatca tagatccagg catgttcttg tcacagccac
     1441 cgatagcgac gaaggcatcc acgttgtgac cactcatagc cgcctcgatg gagtccgcga
     1501 tgatgtcacg agatgttaga gagaaacgca taccaggcgt tcccatagcg atcccgtccg
     1561 ctacggtaat ggttccaaac tgtacaggcc aagcgcctgc agatttgaca ccttctttag
     1621 ccagtttccc gaaatcatgc aagtgaatgt tacatggtgt attttccgcc caagtcgaaa
     1681 tcactcccac aatcgatgtt tcaaagtcct tatctgtcat accagtcgca cgaagcatag
     1741 cacggttagg tgatttaacc atgctgtcat aaatgctact gcggtgacgt ttatctaatt
     1801 cagtcatctt atccctccca tttcagtttt tactattata gcacaatttt cgcatgaaga
     1861 acagaataaa attcttgaat tttcagaaaa ttctatacac atgtgaaata tttaaaatta
     1921 aaaacaacaa agcggattag tgcactttct gatgaccaga atatgctttt taatccgctt
     1981 tctttaaata acgtactgta atttttacag aaattctttc aaataagtgt atttaacatc
     2041 tatcttgcat tataaatttc tagaaccttc tcttttatat tcgattcact caaaccatac
     2101 tcattaagaa gataatccat tttccctact tgaccgaatc tttcttgaac acccatccga
     2161 tgaatttttg ttattccatc atcagagaat aattcacata aagcactgcc aattccacct
     2221 atctgattgt ggttttctac agtaaatata gtttttccac ttaacattgt ttttatctgt
     2281 tctggtatcg gtttgattct aaataaatct atcacaccta ctgaataacc taatttagac
     2341 agttcatctg caactcgaat acttggagca accattatgc cagaagcaac gattacaaga
     2401 tcttcaccat gccttaactc aatgtagcct ttagaaaaat cttctccacc ttgatacaca
     2461 ggaactggag cttttctaat tgttcgaata tattttagtc cttttaagtc taatgtctgg
     2521 ttcaatattt cacgaaattg gatatcatca gttgcttcga aaatgattga tttaggaatt
     2581 aaacgtaaca atccaatttc ttcaaatggc atatgtgttc caccattcat ctctgccgtt
     2641 actcctgcat ctgatccaat cacagtggca tccaattgtg cgtatccaag agaaataaat
     2701 aattgatcaa atactcttcg tgaagcaaaa ggaccaaatg tatgaagata aggtctaaac
     2761 ccctgaatag acaagcctgc tgcaaggccg accatttctg cttccataat cccaacattc
     2821 acataacggt ctccaaagtc cttttcaaga ttattagtag ccatcgaact tgacaaatcg
     2881 gcttctaaga ctactatatc agaatcactt tgattagcct ctaaaaggaa gtctctatat
     2941 acatgccgta attctttcgt acttctcatc attctgtttc ctccaattcc tgacttaatc
     3001 tttctacaac tgaagttaac atttgtttct cctctacagt agggcgaaga tgatgattgg
     3061 atttcatttc ttccagctct tgaacccctt gacctttaat agtatctaat acaatgcact
     3121 taggtgatga attatttgac tgttttaatt ggacaatccc ttcataaatt tctctaatat
     3181 ctgaaccctt gaccctaatg gattcaaatc caaatgctga aaatttttct acgaaatcac
     3241 ctggattaca aatatccttt gtaaaaccat ctaattgttt tttgttatca tcaacaaata
     3301 caattaagtt ggataactgt tgatgagaag caaactgtat agcctcccaa cattgtccct
     3361 catttaactc accatctcca acaatagcgt aagtataaaa gggactcttt cttattctct
     3421 gaccatatgc aagtccagtt gcaacactaa ttccttgtcc taaagagccc gttgtcatat
     3481 ctatgcctgg cgttagattt ctatcaggat gagacggtaa tttggttcca tttgtattta
     3541 aagaatataa gaattctttg tcaaagaaac cattcaaata gagtgtactg tatagagctg
     3601 gtcctccgtg accttttgat aatatgaaat aatctctatc tcgtgctgca aatatttctg
     3661 gagtcattgg cattatttca ccataaagca ccgctaaaac ttctacgata gacagacttc
     3721 ctccgtaatg tccgaatcca agatgattca atgttctaag agtatttaat cggatgttag
     3781 tcgcaaattt tcttaaccca tcttctctat ttttacttaa aatcatccct tattcctccg
     3841 ttgcagatgg ctttttaata aaggatactc caaacataac tgctagaata agaacaagac
     3901 caatcacaat gcctgcttgt gagccaaatt gatttaacat tcctaaaata attcctgata
     3961 gaccaaaatc tgcatctgag aaagttgatc cttggaaacc aagtcctccc aaaactggca
     4021 ttaaaaagac tggaagaaaa ctgattaaaa taccttgtaa aaatgctcca atagtggctc
     4081 cacgaacacc accagatgca ttcccaatga cacctgcagt cgctccacag aagaaatgag
     4141 gcacaacacc tggtaagata acaaccgttc ctgaagcaat cataattacc atacttacta
     4201 aaccaccaac aaaactagag ataaatccaa ttagaactgc attgggtgca taagtataaa
     4261 caatcggaca atccaaagca ggttttgaat taggtacaag acgctctgaa atacctttaa
     4321 aggctggaac aatttcgccc aaaataaggc gaacacctgc taaaataaca aatacccctg
     4381 ctgcaaattg acctgctaat tgtaaagcat aaactagacc acttgtacca ctactgattt
     4441 ctttttctat atattctgac cctgcaaaga tagctacaat aatgtaaata actgccatgg
     4501 ataaagtaat actaacagta ctatcacgta aaaaagctaa actctttgga aatttaatgt
     4561 cctctgttga ttttgatttg tcaccgataa ggctaccagt aaaaccactc aaccaatatc
     4621 ccaaagaact gaaatgacct aaagctacct tgtcatttcc agttaattga accatatatt
     4681 tttgcacaaa tgctggggaa atactcataa taataccgag tgctaatcct cctagtaaga
     4741 tgagaggcaa gctagtaaag ccagcaactg ataaaatgac cgcaatcata catgccatat
     4801 atagagtgtg gtgccctgtt aaaaaaatat atttaaatcg agtaaaacga gcgattaaga
     4861 tattgaacac catgcctgca aacataatca ttgcagtagc tgagccatat gttgttaaag
     4921 ctacagctac aattgcttca ttattcggca caacgccaga taaatgaaaa gcatgctcaa
     4981 acatggtacc aaatggattt aaagaatttt gtacaattcc tgcaccacca gatacaacta
     5041 agaaaccaac aaaggtctta attccacctt taataatatc aggtaatttc ttcttctgaa
     5101 gaactaatcc taagattgca attaaagcta ctaaaatagc tggtgtacta acaatatcca
     5161 atatgaactt catcatgacg ctagcctcct atataagtcc tttttcttca caaagtttag
     5221 taattaattc tcgtagttca tccatatcaa taatactatt taagatacga acatctccaa
     5281 gatgactagc tgaatcagct agatcacgac caacaatcca aatatcagct gcatttggat
     5341 ctgctccacc taaatcataa tgttcaactt ctacatccga aacattcaaa tcactcaata
     5401 cagattcaat attcatctgt accataaaac ttgaacctaa tcctgaacca caagctgtac
     5461 caatttttaa cattatctaa tcctcctgtt taattatcat tttaatgtca tcatagtttt
     5521 ttgatgatat taaagtttga acatgatttt tatctcttaa aattgttgtt aaatgtgaca
     5581 aagcctttaa atgactctca ttatcaatgg ctgcaataca aatcaacaat cttacctctt
     5641 gttctggatt atccaataaa taaatcggtt cttccaaaac taacattgac attcctattt
     5701 cattcacacc ttcatctggc cgagcgtgag gaattgctac tcccttccct aaattaataa
     5761 aaggtccaaa ctcttctact ttttgaatca ttgcctcagg gtagttctca gttatcttat
     5821 cttgatccaa aagcggttta gctgctaaac gaatcgcctc cttccatcct aatttttgcg
     5881 aactaacctg ataggtttct ttggtaataa gttgttctag cactggtaca atttcctttc
     5941 tatcattttt ttggtaaaga taattcttta acgccaatct taattccaat tcttgtgtaa
     6001 taattccata tcttttgaca atattcagga tttgttcaat ctcaaaatct ccatactcta
     6061 aattcggaaa atcttttaac actagttcta ctagttgtat tgcttgctct tcagtcatca
     6121 taaccgaaac tagataattt ggcttttctg tctccacctt tatggtagaa aaaaccatat
     6181 catagtcact actagctttc acctgtaaat catcaatctt tgaggttcct ataaactcaa
     6241 tttgaggaaa taatgctaat agattctctt ttaacatcaa tgaagaacta acaccattag
     6301 gacaaatgat tgctgcttta taccattttt gaggcaaagt atctgctttc tttaaataac
     6361 ctccgaaatg gataacaaaa tatgctgttt cactatcagg tatgggattg tcaatagcgt
     6421 ccatcaaggg catcaaagaa tctttgacta attcaaataa atcaggataa tgttctttaa
     6481 catgcaatac atattcattt gaactaggta ggccgaactt taatctatag taagccggta
     6541 taaggtggcg gcgaagattt tctctcaatc cttccctttg tttaaaatgt aacaaagaaa
     6601 tatcttccat tctacttata atagcctctg ttaattgatt aaagtaaacc ggagcaacat
     6661 ctacttcacc ttcaaagcaa cttgataata aaacggtgat atagcgataa tcatcctcag
     6721 aaaacaccgt atctataatt cccaaatcaa ccactgtatc caataaaata gtggttatat
     6781 cttgaataac aggagatact aatgtctctg aaagacatac tctttcaaca tccctttgat
     6841 acctacacag aatgaatact aaaccgaaaa ggtaaacttt taattgatta acaataggta
     6901 ctagctgtag cttctcataa taatctttaa ctacctgatc aatcaaatca taagttaatg
     6961 aataccccca actggataaa acataatcca aaccccaaat ccctatggag gattccagca
     7021 actcactaac catttgaaaa gctaagcggt gcttattcca ctctgaaccg tgtaaagtat
     7081 aaccttttgc tctactgtac cctagctcca aatcattatc taacataatc tttcttaatg
     7141 attgaatatc agataaggtt gtattcttac ttactttcaa aaagtcttgg taatgactat
     7201 tcgatataaa atctaatcgg caaaaagtgt aaagatagat taaagctaag cgagtcgact
     7261 ttggtaaaac caattcatcc gacttaataa tatctgtcaa agactgcttc gtacgatttg
     7321 ataaactata gcgaccttgc tttttatcca gcactatccc tttattagct agataaggca
     7381 ctaaataatc tattccttct ttgacttcct ttataggtaa gctcacctta acagataatt
     7441 catataatga tagctcacaa tgatccatca aagtcatcaa aataactagt gctctataat
     7501 caaacatttc tcttcctttc taactacaat tatagtgtaa aaattataag aataaaagag
     7561 tatttgagca caatataatc tcacctttta aaagaaatta ttgggctgaa agtttttagt
     7621 gattattttt caactttcta ttgactttat aaattaaagt gatatcattt agatatcaaa
     7681 taacaggagg tcattcttat gactgaaaaa ctaatcaatt caaaaccaaa tggtgtattc
     7741 gcattgattc tcattgagtt gacaatcgta cttggtatct ttatatttat aatgggggtt
     7801 ggttcggaaa acatttttgg aattattatc ggacctttac taatcgtaat tgcaggtcta
     7861 gctcatgctg gtttaaaagt tgtcaaacct caagaagctc tggttctgac actctttggt
     7921 aactatacag gtaccatcaa agaacctggc ttttactttg tcaatccctt cagcgtagca
     7981 gtcaaccctg caaaccacac tcgacttgga caaagtggtg atgttagcac aaaatctcct
     8041 tttttaggag ctaaatcatc aaatgacaat gatgtaaatc ttgaaattgg caagaaacag
     8101 atttccctca aagtcatgac cttgagcaat tctcgtcaaa aaatcaatga ttgcttagga
     8161 aaccctgtag aaatcggtat cgcggtaact tggagagttg tcgataccgc taaggcagtc
     8221 ttcaacgttg ataactacaa agaatatctt tcattgcaat gtgatagcgc cctccgtaat
     8281 attgtccgca tctatcctta cgatgtgtct cctaatgtgg atactacggg tgatgggcaa
     8341 gcagatgaag gtagtctccg tggctctagc gaaattgttg ctaaccgtat tcgtgaagaa
     8401 atccaaagtc gtgttgagga tgctggcttg gaaatccttg aagcacgtat cacttaccta
     8461 gcttatgctc cagaaattgc tgccgttatg cttcaacgcc aacaagcatc tgccattatt
     8521 gatgcacgga agatgattgt agatggtgct gtaggaatgg ttgaaatggc actagaacgg
     8581 ctcaatgaag gggaattggt agaacttgac gaagaacgaa aagctgccat ggtttcaaat
     8641 ctccttgtcg ttctttgtgg caatcatgat gcacaaccaa ttgtcaacac aggaagcctt
     8701 tactaaagat ggctgaagct aaaaaaaagc agatccccct tcgactctca acaaagttat
     8761 acgctgcact cgcatcatgg gcagaagacg actttcgttc agtcaatggg caaatcgaat
     8821 atctcctcac agagtgtgtc aagcaacgga agaaagacgg aaaatacgta tcagaaacca
     8881 ttgacgaacc atttgagatt gatatttaac accttctcct gtctgccgtg tcggatagga
     8941 gaattttttc atcttttttt gtcaagtaac tttactttac aaaaaaaatg tgttatccta
     9001 gtatggttga tgaaaatcag tagattgaat cgaatataaa tacctaaagg agaaatcaaa
     9061 atggcagtac ctgcacgtcg cacttcaaaa gcgaagaaaa acaaacgtcg tacacactac
     9121 aaagtaacag ctccatctgt aaactttgac gaaactactg gagattactc acgttctcac
     9181 cgtgtatcac ttaaaggata ctacaaagga cgtaaaatca ctaaagctgc atcagctgaa
     9241 taatagaagg gagataccat gcgcgtaaat attacacttg aacacaaaga atctggtgaa
     9301 cgcttgtacc ttacttctaa aaacaaacgt aacactccag accgccttca attgaagaaa
     9361 tactcaccaa aacttcgcaa acacgttgtg tttacagagg ttaaataagc attcaatacg
     9421 aatcaataca gaagaaaaac gcttgatcag cgttttttct ttttgttaat ttcactacat
     9481 tgtaagggaa atcattcgaa tgactacatt tttcactacc ttttttgaaa taagaatacg
     9541 gattcggaca attaaaagca agaggaactc aaatgtaagt tggggttcct tttttgtata
     9601 tttttcaaat aacgcctcta cactatttgt agcaaattca ccaactacag ttgtatctta
     9661 gttaaaataa gttagaatat gtaagtgagt accagatata ccaagacatc gtcaccatct
     9721 aaggtatatt caaaatacaa aagttgacca actagatttc tgaatatcct tatatatcca
     9781 ttcttaaaat tggtttaaat agcgtagtct tttaaactag ttttgagaat ccaaaaaatc
     9841 ttcctacata tgtaagaaga ttttttagtt cagaatgatt agatttagct aatggatacc
     9901 tatcctaccc actcaccgtt agcattgact cgatagccat cgggtgtagt cgtgtttact
     9961 aataaatctc ctgaattata ggtatagtac catttaccag aaactgtaac ccaaccagta
    10021 gccattgaac ctgattcatt taagta
//
LOCUS       DAVAZT010000069         9471 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVAZT010000069 DAVAZT010000000
VERSION     DAVAZT010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9471
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.069"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            150..686
                     /locus_tag="VQT45_001869"
     CDS             150..686
                     /locus_tag="VQT45_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HET2360142.1"
                     /translation="MKKAHVYAIPAIGAALIAALAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALAVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            737..823
                     /locus_tag="VQT45_001870"
                     /pseudo
     CDS             737..823
                     /locus_tag="VQT45_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(892..1107)
                     /locus_tag="VQT45_001871"
     CDS             complement(892..1107)
                     /locus_tag="VQT45_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HET2360143.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            1205..1525
                     /locus_tag="VQT45_001872"
     CDS             1205..1525
                     /locus_tag="VQT45_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360144.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(1556..1894)
                     /locus_tag="VQT45_001873"
     CDS             complement(1556..1894)
                     /locus_tag="VQT45_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360145.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(1906..2625)
                     /gene="trmD"
                     /locus_tag="VQT45_001874"
     CDS             complement(1906..2625)
                     /gene="trmD"
                     /locus_tag="VQT45_001874"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HET2360146.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(2615..3133)
                     /gene="rimM"
                     /locus_tag="VQT45_001875"
     CDS             complement(2615..3133)
                     /gene="rimM"
                     /locus_tag="VQT45_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HET2360147.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKRYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(3164..3952)
                     /locus_tag="VQT45_001876"
     CDS             complement(3164..3952)
                     /locus_tag="VQT45_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2360148.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFEDVSIEAHIPVFVFCQP
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            complement(4529..4768)
                     /locus_tag="VQT45_001877"
     CDS             complement(4529..4768)
                     /locus_tag="VQT45_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HET2360149.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(4788..5060)
                     /gene="rpsP"
                     /locus_tag="VQT45_001878"
     CDS             complement(4788..5060)
                     /gene="rpsP"
                     /locus_tag="VQT45_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HET2360150.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            5230..5439
                     /locus_tag="VQT45_001879"
     CDS             5230..5439
                     /locus_tag="VQT45_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360151.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            5918..6139
                     /locus_tag="VQT45_001880"
     CDS             5918..6139
                     /locus_tag="VQT45_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360152.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            6222..7025
                     /locus_tag="VQT45_001881"
     CDS             6222..7025
                     /locus_tag="VQT45_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET2360153.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQSSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(7081..8622)
                     /locus_tag="VQT45_001882"
     CDS             complement(7081..8622)
                     /locus_tag="VQT45_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2360154.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMEMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DLPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(8624..9106)
                     /locus_tag="VQT45_001883"
     CDS             complement(8624..9106)
                     /locus_tag="VQT45_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET2360155.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVGVGTPDIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(9106..>9471)
                     /locus_tag="VQT45_001884"
     CDS             complement(9106..>9471)
                     /locus_tag="VQT45_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S rRNA methyltransferase"
                     /protein_id="HET2360156.1"
                     /translation="KLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALELAELLKNI
                     KKSSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGGNCVVRQEHGTDIDAACGQ
                     LLFNTMKRDRQKAVAAVNP"
BASE COUNT         2796 a         2028 c         1698 g         2949 t
ORIGIN      
        1 attttcgaat caacaaaaaa attatccaac ttgactagtc acgaaaatcg gctgttacag
       61 tttttgttac cttgttttta aaaaatggtt gacatcgact cctatatgag tataatagtt
      121 atcatacatt agaaaagagg ttaactattt tgaaaaaagc tcacgtttat gctatccctg
      181 ctattggggc tgctctcatt gctgctttgg cacaaatcag tcttccaatt ggacctgttc
      241 ccttcactct gcaaaacttt gcaatcggct tgattgctac tgtctttaga ccgagagagg
      301 ctgtactttc tgctggactc tatcttcttc taggtgctat cggtcttcct gtctttgcag
      361 gaggtggagc tggttttcag gctttagttg gccctactgc aggctatctt tggttttatc
      421 tcgtttactc tggacttact tcctctctaa ccaacagcaa gagtggtgtt gttaagattt
      481 ttcttgcaaa cctcttgggt gatgcccttg tctttgtcgg cgggattctc agcttgcatt
      541 tcctagctgg aatggcattt gaaaaagctc ttgctgtggg ggttcttccc tttatcattc
      601 cagaccttgg caaacttctg gctattagtt ttattagccg tcccctactt caacgcctta
      661 aaaatcaggc ttactttact aactaaaaaa ggatatcgag ttatcatgac tcaatatcct
      721 tttcttttat tttgaaaact tatactcaat gaaaatcaaa gagcaaacta gaaagctagc
      781 cgcaggctgc tcaaaacact gttttgaggt tgtggatgaa actgacgaag tcagtaacca
      841 tacatacggc aaggcaaagc tgacgcggtt tgaagagatt ttcgaagagt attagttgcc
      901 tttaaaggca tccaccatcg tttgaaattc ttcatttgag agagtaatcc ctttgcccat
      961 tttagtatgg tctggactcc aagcacgaat atcaaacttt gcaggggcac cattaaagct
     1021 cacacggtta atttccttgg tccaaccttt ttcgttttca gaaagagtca acaagtgctc
     1081 ttcgatttca aatgtaaatt ctgccatttt cttctccttt tttagtttca ttagtttatt
     1141 cgtaaaatct tgtagatttt aggaaaattt tatataatat tgatataaaa gaagggaggc
     1201 caatatgaga cataaattcc agcaagttct aaataaaata catgattttt taaatggata
     1261 tgaccaacct gaccagactg aaaccaactc ccttacagcc actattgaag aggctatcca
     1321 gaaacaaacc gctgttcacc ttatcttgtc tgagacaagt tttacaggtg atatcatcaa
     1381 atatgatcag caaggccagc aaattatcgt gaaaaatttt gccaaaaatg tgagccggat
     1441 tatccgtata agcgatattc aacgcctgcg atttgtcccc tcaactgtcc aaacagccca
     1501 aaaaaataga tttaagaaag agtgagatgt agttgcttca tcccactctt ttttcttagc
     1561 gaatttgttc aaaatgtaaa tgaactgcaa tatgatctcc ataaccactt ctttccaagt
     1621 cacgttgtaa acgataggaa atgtagtgtt ctgcaatggt aatgtaacct gcgcccaata
     1681 aacgatgttc aaccatagat tgaatcatac tgatagtcgc acgttccacc ttggcttctt
     1741 gtaaatccaa aactaccttc ttagtgactt gagcaagatt ttgacgcaaa tcatctgtca
     1801 aaacataaac agtttgggct gccttcaaga tggcttggta aatcttatct ggattaaatt
     1861 cagcaatttc gccattacgt ttgattactt gcataggttt ctcctttatt ctttgttttc
     1921 tttgatttct gccagcattt tttcttcttc tactgtcagt tgataatgtt caagtaaatc
     1981 cggtctgcgc tcgtaggttt tctttaaact ctcgtacaat cgccactgac gaatcttttc
     2041 atggtggcca ctcatcaata catctggcac gaccatgcct cgataatcat agggacgtgt
     2101 gtactgagga tattctaaaa gacctgaaga aaaactatca tcttggtggc tagactcctt
     2161 gccaatcact tctggaatca ggcgaactgt agcatcaatc atggtcatag ctgccaattc
     2221 tccaccagtg aggacatagt cgcctaggga aatctcatct gttaccaagg tcttaatgcg
     2281 ctcatcataa ccctcatagt gcccacagat aaagattagc tcttcctctt gagccaaatc
     2341 ttcagcataa gcctgatcaa actgctttcc agcaggatcg aggagaataa cgcgcggatt
     2401 tttcttttca atagcatcaa aggaatcgaa aataggttgt gctctgagca acatgccctg
     2461 accgcctccg tagggctcat catctacatg acgggccttt tcagcatttt ctcgaaaatt
     2521 atgatactgg atatccaaga gccctttttc tcgagccttt ccaacgattg agtgctccag
     2581 tggagaaaac atctctggaa agagggttaa aatatcaatc ttcatcgtct aacccttcta
     2641 agatttccac atcgacccgt ttatttggaa tatcaacatt gagaaccact ggtgggatat
     2701 aaggtaaaag caaatcacgt ttgccttttc gtttgaccac ccagacatca ttagcacctg
     2761 gttgcaggat ttccttgatg gttccaacca agctatcacc ctcatagact tccaaaccga
     2821 taatctcgtg atagtaaaat tcaccatcgt ctaggtcatt caaatcttcc tcagcgacct
     2881 tgagactata tctcttgtac ttttcgatag tattgatatg gtacatatct ttgaatttaa
     2941 taatgtcaaa gttcttctgt ttacggtggc tagcgatggt cactgtttgg acaaactgat
     3001 ctttttcatc aaacaaagcc agctcagctc cttttttaaa ccgttcttct gcaaaatccg
     3061 tcacagacaa gactcgcatc tcaccctgta atccctgcgt attaacgatt ttcccaacat
     3121 taaagtagtt catcttgtct cctgtaatct ccttttttcc atcttattct gacaattctc
     3181 gaataatagc cgcaattttt tccgattctg accattgtaa ataatggtga ttccctccta
     3241 aaatgagttt agtattggaa gtccaatatt ctgattctct gtactctttt tctctataag
     3301 gctgacaaaa aacaaataca ggaatatgag cttctataga tacatcctca aaatcttcct
     3361 cagtaatctc tccagatatc tgaaattctg gatcttgatt ttccaactct aagccttttt
     3421 cttgcattaa ttcccagatt tttttattcg tttcaggact aaatgttgct tgagttaagt
     3481 tcttaaaata aagttcagga ccacactcgt caatcagcct catctgctct tccatttctg
     3541 gataaggatt ttctgaaaaa tcagcaaaca tgactttttt agttgtcggt tcaattgcta
     3601 ctaaagtctg acgcttaatt ggtttctcga gtaatttgca agctaaaatt ccactccaac
     3661 tatgtgcaca aagtatatat tcagaaattc ctaattcttc aagtacttca taaaccgcat
     3721 ctgcaagatt atctagattt tttccagctt ggtcatgaat cggactccta cctgtgttcg
     3781 gaaaatcaat tgtcaaataa ccaattgtag gaggaggttt ttcaagtata agtgaaaaat
     3841 tttcataact tggtagcaaa cctgctccgt ttagacaaac tagcactttc ttttgctttt
     3901 gataagtaac agagaggcta ccaatttctg tagatacttc aaacctcttc ataaagaaat
     3961 ccactcattc tatataatga attattaaaa atccttatct tttattttat cacgttccaa
     4021 ggattttctc aagttggagg aaggggacaa catctctact ttcccttcaa aaatccttcc
     4081 aaatcatgtt tatgttggta attaacggct gcggttttgt ctttctcaaa gacagtcttg
     4141 gtaaggtcaa tatgattaat agctacgatt gcgacggtgt agtaaatgat atcagccagt
     4201 tctctggcaa gttcctcgtt cgaatcctat cccttctttt cgaccagagc gcctattcaa
     4261 aacctcggct acttctccga cttcctccac taacttcata aagagacctt catcagtccg
     4321 agactgctgt taatgttcga ttaagtagtc ttggaattgc ctaaacgttc aatcttttat
     4381 agtatattga aactagaata gtacaccttt acttctaaaa cattgttaga aatcgatttg
     4441 actgtcctga tcgatttgtc ctgttcttgt ttcattttac tatatcttct attccacaca
     4501 aaaaagcgag acatccgtcc cgcccttctt atttttcgtc aataacgatt cttacttttt
     4561 tgtattcagt tgggacagag tagacaatcg ttcttatcgc agaaatagtg cgacccttac
     4621 gaccgattac acgacccaca tcgctttgat caagattcaa atgatattcc aaaaattctg
     4681 gtgtatcctc aatcttgata gttaaggcat ctggttgtga aattaagggt ttcacaatcg
     4741 caataatgag attttcaatc gtatccatct gtcaacctac tttaaactta ttttgaaaat
     4801 ttagaatcgt ggaatttttt caatacgcct tcttttgaaa ggatgttacg tactgtgtct
     4861 gaaggttgag ctccattagc caaccatgca agaacgcggt cttctttcaa agttacttgg
     4921 ttttcagcaa caagtgggtt gtaagttcca actgtttcga tgaaacgtcc gtcacgtggt
     4981 gaacgtgaat ctgctacgtt gatacggtag aaaggttttt tcttagaacc catacgagtc
     5041 aaacggattt taactgccat ttttaaagtc tcatttcttt aattttttat ttcggtgaaa
     5101 tagctgagct atttagcaca tgttctatta tagcagattt ctggcatgtg tcaagaaaaa
     5161 aacttgacag actataaatt tcttaaagta tttagaaatt tgttagaata ggaaataaat
     5221 gtttgaaaga tgctatccgt gaatactatt ttagaaaaat tttataaaga acaccaagtc
     5281 aaacccttca tatcgcctga acgagagttg gatacttggc ttctaagtcc caagcccgtt
     5341 cccaagcgaa atatggactt attagtagat gattcactag caggagatat cattttacta
     5401 tggagaatcc agtttggtac ttttaccact gaaacatgat tttaaaaact cccattcgaa
     5461 tatgattcaa aattcgctta gaatcaatgt tttcccgctt tttcaaaaaa taaattttca
     5521 tctaatttaa ataactttca attaagtgtg aattttgctt aaaatcatta aaaagcaccc
     5581 catggtgtga accatgaagt gttgtaaatg ctgtgttgta gctagttctt agcgtttaga
     5641 gaactggcta gctttacgag ctttcttaag atctggtttc caaaatactt tgagtacact
     5701 tatggtattg atgcccctaa acatctaaaa actctggtag aaaaagggta tgctcttgtc
     5761 gaaacttctt ttgactcact tgaccatcta aataatacca tgaaaaagaa tatcctgaag
     5821 aagaagggag ttactggact ttctaaaatg aaatcttgcg acctggatca agcccttcat
     5881 gagcattttt cagaagaaga attagctggt cactttcatg tccttctatg gactttttta
     5941 caatggcatt gctatcacac ccaataccta tctaagcgcc tggttcgtaa actttattgc
     6001 agctcttcct ctaaatttcc taattgttga accaattgcc cgttttatac taagttcttt
     6061 tcagaaacca tttactgggg aagaagttga agaagttgaa gattttcaag atgatgatga
     6121 aatcccaact attatctaag ccagttctgt aaactactaa tatttgaaat ccacttcttt
     6181 ttagggtaca atggtataaa tgaatttttg agaggatcag aatgaaaaaa ctagcaaccc
     6241 ttcttttact gtctactgta gccctagctg ggtgtagcag cgtccaacgc agtctgcgtg
     6301 gtgatgatta tgttgattcc agtcttgctg ctgaagaaag ttccaaagta gctgcccaat
     6361 ctgccaagga gttaaacgat gctttaacaa acgaaaacgc caatttccca caactatcta
     6421 aggaagttgc tgaagatgaa gccgaagtga ttctccacac aagccaaggt gatattcgca
     6481 ttaaactctt ccctaaactc gctcctctag cggttgaaaa tttcctcact cacgccaaag
     6541 aaggctacta taacggtatt accttccacc gtgtcatcga tggctttatg gtccaaactg
     6601 gagatccaaa aggggacggt acaggtggtc agtccatctg gcatgacaag gataagacta
     6661 aagacaaagg aactggtttc aagaacgaga ttactcctta tttgtataac atccgtggtg
     6721 ctcttgctat ggctaatact ggtcaaccaa acaccaatgg cagccagttc ttcatcaacc
     6781 aaagctctac agatacctct tctaaactcc ctacaagcaa gtatccacag aaaattatcg
     6841 aagcctacaa agaaggtgga aaccctagtc tagatggcaa acacccagtc tttggtcaag
     6901 tgattgacgg tatggatgtt gtggataaga ttgctaaggc cgaaaaagat gaaaaagaca
     6961 agccaactac tgctatcaca atcgacagca tcgaagtggt gaaagactac gattttaaat
     7021 cttaaaaacc aaaaaaatac agtatccaca ttcggtactg tatttctttt actctcattc
     7081 ttaagttaaa ttattaaaat cccatatttg gtctatccag ccttcataaa agtctggctc
     7141 gtggcagacc ataaggatag atcccctata ttctttgaga gcgcgtttga gctcatcctt
     7201 tgcatccaca tccaaatggt tggtcggctc gtccagcact aaaacgttgt tttcacgatt
     7261 catcaagaga cagaaacgaa ccttggcttg ctctccccct gataatactt gaatctggct
     7321 ttcaatatgt ttggttgtca aaccacaacg ggcaagggct gcacggactt ctgcttgatt
     7381 aagggcagga aaggcattcc agacagcttc aagaggagtt tggcgattac cgccttctac
     7441 ttcctgctca aaataaccaa gttctaaata atctccacgc tccacttccc cagcgattgg
     7501 cgagataatg cccaagagac tcttcaagag agttgttttt ccaataccat tagcaccaat
     7561 aatcgcaacc ttttgattgc gttcgaaggt aagatttaaa ggcttagtaa gaggaaggtc
     7621 gtaaccaatt tgcaagttct tggcttggaa gataaagcgc cctggtgtac gagctggttt
     7681 gaaatcaaag gatggttttg gtttctcact ttggagttcg ataatatcca tcttatccaa
     7741 tttcttttga cgagacatag ccatattacg agttgcaaca cgggctttat tacgagccac
     7801 aaagtccttg aggtctgcaa tctctttctg ctggcgttcg taggctgcct ctagctgaga
     7861 tttcttcata gcataaactt cttggaactg gtagtagtca ccagagtaac gcgtcagctg
     7921 ttgattttcc acatgataga caatattgat aacgtcattg aggaatggaa tatcgtgcga
     7981 aatgagaaca aaggcattct catagttttg gagatagcgc ttgagccaat caatatgctc
     8041 agcatccaag tagttggtcg gctcgtccaa cagcaagata tcaggctttt caaggagaag
     8101 ttttgccaaa agcaccttgg ttctttgccc acctgacaaa gaagttacat ccgtatccat
     8161 gccaaagtcc ataacaccaa gagcacgcgc tacttcgtca atcttagcat ccaaggtata
     8221 gaaatcacga ctctccagac ggtcttgaag ttctcctact tcttccatga gagcatcaac
     8281 atccgcaccg tcttcagcca tttccatata gaggtcattg atacgagctt cagctttgaa
     8341 aagctcatca aaagccgtac ggagaacatc acgcaccgac tgtctttcag caaggacaga
     8401 gtgctgatcc aagtaaccag ccgtcacata tttggaccac tcaacctttc cttcatctgg
     8461 cagcatttta ccagtcacga tactcataaa ggttgatttt ccttcaccat tggcaccgac
     8521 caggccgata tgttctccct tgaggagacg gaaggacaca tcttcaaaaa ttgcacggtc
     8581 accaaaaccg tgactcagat ttttaacttc taaaatactc attttaattc cttatcttgt
     8641 ttttatgtaa tcgtttataa aggagccaag ccagatagcc acccaaagtg ttggtccaca
     8701 aatcatcaat ctcaaagacg cgattgaaat caaagaaaaa gtccaagatt aattgcgtac
     8761 actcgattcc aagactcaca agaaaactaa aaagaaggac cttttttgtt ttccgcaaat
     8821 ttggaaatag ataaaggagt tggaaaatca gaggaaaaaa caagaagaca ttgaggatat
     8881 tttgtaaaaa aatccaacat aattgtccaa tgtcactcac ttcgcccagt ttccagagag
     8941 aattgaaagg agtcaaaaga aaaaccaggc gtccaagatg ctgaatatct ggagttccca
     9001 ctcccacggt agattgttct tgaggagtaa agcaaaaata gacaatgcaa atgctataga
     9061 aaatgactcc ccagaccaaa atatgattat aagtcttctt catcattaag gatttaccgc
     9121 tgcgactgcc ttctggcggt cacgtttcat tgtgttaaag agcaattgtc cacaagctgc
     9181 gtcaatatct gtaccatgct cttgacgaac cacacagttg cccccttttt tcttaagcgt
     9241 atcatagaaa gccaacacgc gctctttggg actacggcta tattggtcat gctcactaac
     9301 tgggttataa ggaatcaagt ttacataaga cgatttcttg atgttcttga gcaattcagc
     9361 caattccaag gcttgttcca caccgtcgtt gacttcatta agcatgatat attcaaaggt
     9421 tacacgacgg tttgttgtct caatgtagta ttcaatagca gcaaagagtt t
//
LOCUS       DAVAZT010000070         9136 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVAZT010000070 DAVAZT010000000
VERSION     DAVAZT010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9136
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.070"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            1..294
                     /locus_tag="VQT45_001885"
                     /pseudo
     CDS             1..294
                     /locus_tag="VQT45_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466308.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            370..819
                     /locus_tag="VQT45_001886"
     CDS             370..819
                     /locus_tag="VQT45_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000337416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2360157.1"
                     /translation="MCTILVSIYYKIGLSSSGVYKAVADGEMTVSLSYEDPAVKLLND
                     GANIKVVYPKEGTVFLPASAAIVKKSKNMENAKKFIDFIISQEVQDTLGTTTTNRPVR
                     KNAKTSENMKPIDKIKTLTEDYDYVIKNKSDIVKKYNEVFTDIQSKQ"
     gene            832..1491
                     /locus_tag="VQT45_001887"
     CDS             832..1491
                     /locus_tag="VQT45_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2360158.1"
                     /translation="MSEIEIINAKKIYHDVPVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIEGGEFYFDDTKINNMEPSKRNIGMVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLELMQIAQYADRKPDKLSGGQQQRVTLACALAVNPSVLLMDEP
                     LSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRP
                     K"
     gene            1618..1923
                     /locus_tag="VQT45_001888"
                     /pseudo
     CDS             1618..1923
                     /locus_tag="VQT45_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809465.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TOBE domain-containing protein"
     gene            1913..3558
                     /locus_tag="VQT45_001889"
                     /pseudo
     CDS             1913..3558
                     /locus_tag="VQT45_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(3661..4353)
                     /locus_tag="VQT45_001890"
     CDS             complement(3661..4353)
                     /locus_tag="VQT45_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET2360159.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGCEKMEEGSI"
     gene            complement(4597..5934)
                     /locus_tag="VQT45_001891"
     CDS             complement(4597..5934)
                     /locus_tag="VQT45_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HET2360160.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALTETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     IGDSVARVLEEMGLETVGTHGTTVALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            complement(5944..6210)
                     /locus_tag="VQT45_001892"
     CDS             complement(5944..6210)
                     /locus_tag="VQT45_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HET2360161.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            complement(6475..6861)
                     /gene="rplQ"
                     /locus_tag="VQT45_001893"
     CDS             complement(6475..6861)
                     /gene="rplQ"
                     /locus_tag="VQT45_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HET2360162.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(6873..7808)
                     /locus_tag="VQT45_001894"
     CDS             complement(6873..7808)
                     /locus_tag="VQT45_001894"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HET2360163.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            complement(7851..8234)
                     /gene="rpsK"
                     /locus_tag="VQT45_001895"
     CDS             complement(7851..8234)
                     /gene="rpsK"
                     /locus_tag="VQT45_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HET2360164.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            complement(8252..8617)
                     /gene="rpsM"
                     /locus_tag="VQT45_001896"
     CDS             complement(8252..8617)
                     /gene="rpsM"
                     /locus_tag="VQT45_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HET2360165.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            complement(8635..8751)
                     /gene="rpmJ"
                     /locus_tag="VQT45_001897"
     CDS             complement(8635..8751)
                     /gene="rpmJ"
                     /locus_tag="VQT45_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HET2360166.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            complement(8776..8994)
                     /gene="infA"
                     /locus_tag="VQT45_001898"
     CDS             complement(8776..8994)
                     /gene="infA"
                     /locus_tag="VQT45_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HET2360167.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
BASE COUNT         2766 a         2044 c         1567 g         2759 t
ORIGIN      
        1 tcaaaagaaa atgataatgt tatcaaagaa tatcaaaaca caactggctt ctctactcct
       61 tatacactag atggtagtgt tttaatcgtc caccctgatt taactaaagg catgaacatc
      121 gaaggatata gcgaccttct caaacctgaa ctaaaaggaa aaatcgcaac tgctgaccca
      181 gcaaactctt ctagcgcctt tgctcaatta acaaatatgc tacaagctca aggtggttac
      241 aaagatgata aggcttggtc ttatgtaaaa gatcttttca cacttattga tggtatagta
      301 aaatgaaata agaacaggac aaattaatca ggacagtcaa atcgatttct aacaatgttt
      361 tagaagtaga tgtgtactat tctagtttca atatactata aaatcggttt aagttcatct
      421 ggtgtctata aagcagtcgc tgatggagaa atgactgtta gtctctctta tgaagatcca
      481 gcagttaaac tcttaaatga cggagctaac attaaggtag tctatccaaa agaaggaacc
      541 gtcttcctac ctgctagtgc tgctatcgtt aaaaaatcta aaaatatgga aaatgccaag
      601 aaatttatcg attttattat ctctcaagaa gtacaagata cacttggtac aaccactact
      661 aaccgtcctg ttcgtaaaaa tgctaaaaca agcgaaaaca tgaaaccaat tgacaaaatc
      721 aaaacactca ctgaagatta tgattatgtc atcaagaata aatcagatat cgttaagaaa
      781 tacaacgaag tctttacaga tatccaatct aaacagtaaa agaggttcac tatgagtgag
      841 atcgaaatta ttaacgccaa aaaaatctac cacgatgtcc ctgttattga gaatttgaac
      901 attacaattc caaaaggaag tctctttacc cttcttggag cttcaggatg tgggaaaacg
      961 acccttcttc gtatgattgc aggtttcaac agtatcgaag gtggagaatt ttacttcgat
     1021 gatacaaaaa tcaataatat ggaacccagc aaacgcaata tcgggatggt tttccaaaac
     1081 tacgctattt tcccacattt gactgtccga gacaacgttg cttttggtct tatgcaaaag
     1141 aaggttccaa aagaagaatt gattcaacag accaacaagt atcttgaact catgcaaatt
     1201 gctcaatatg cggatcgaaa gcccgataaa ctcagtggtg gacaacaaca acgtgtcacc
     1261 ttggcatgcg ccttagcggt taatccaagt gttctcctca tggacgagcc acttagtaat
     1321 ctggaggcca aacttcgctt ggatatgcgt caagccatcc gagaaatcca acacgaagtg
     1381 ggaattacaa ctgtttatgt aacccacgac caagaagaag ccatggctat ttcagaccaa
     1441 attgctgtta tgaaagatgg ggtgatccaa caaatcggcc gaccaaaata actctatcat
     1501 aaaccagcta atgagtttgt ggcaaccttt atcggacgca caaatattat ccctgccaat
     1561 cttgaaaaac ggagcgacgg cgcttatatc gtcttttcag atggctatgc ccttcgaatg
     1621 ccagctcttg atcaggttga ggagcaagct attcatgtaa gcattcgtcc cgaagagttt
     1681 atcaaagatg aatctggaga tatcgaagga actattagcg atagcgtcta tcttggacta
     1741 aatacggagt atttcattga gacaggtttt gcctcaaaaa tttaagttag tgaagaatca
     1801 acttttgaag aagaactaca aaaaggcaat cgtattcgtc tacgaatcaa tacgcaaaaa
     1861 ttaaacatct tttctgcaga tggttcccaa aacctgataa aaggagtcaa ccatggaatg
     1921 taaaaaacta aatatttgga cagcttcctc tttcttcatc tttcttacct atcttgtctt
     1981 tctcgtttat cctatcgtta ccgtgctcaa gcaagcactt atacatgaag gacaattctc
     2041 actagctaat tttgtcactt tctttagtaa agcctactac tctgagacac tagtcaacag
     2101 tttcaaggtt tccattaccg ctactatcac ttccttagtt gtaggaaccc tattagctta
     2161 tctcttctct atgtatgact tcaaggggaa gaaatttcta caaatattga ttatcattgc
     2221 ttccatgtca gctcctttcg taggagccta ctcctgaatt ctcttgctgg gacgaaatga
     2281 ggtcatcact aaatttttga caaatgccct tcatcttcca gctatcgata tttatggatt
     2341 caaaggaatt gtacttgtct ttacactgca actattccca ctggtatttc tatatgttgc
     2401 tggaacaatg aacagtattg acaattctct acttgaagca gctgaaagca tggggtcctt
     2461 cggatttaag cgtatcgtaa cggttgtttt acctctccta gttccaacct tactagcagc
     2521 tccttgcttg tatttatgag agcattctca gactttggaa cgcctatgtt gattgacgaa
     2581 ggatatcgga ctttccctgt cctgatttat acccaattta ttagcgaggt tggaggaaat
     2641 tctgcttttg caattatggc gattatcatt gccttggcaa ttttccttat ccaaaaacac
     2701 attgcaaacc gctacagttt cagcatgaat ctgctccatc caattgagcc taaaaaaact
     2761 acaaaaggaa aaatagctgc catttatgca acagtctacg gaattatctt tatctctgtt
     2821 ttacctcaaa tctacttaat ttatacctct ttcctaaaaa catcaggtat ggtatctgtt
     2881 aaaggttatt ctccaaacag ttacaaggta gctttcaatc gtatgggatc tgctattttc
     2941 aataccattc gtatcccttt gattgcctta gttctagttg ttctatttgc gacatttatc
     3001 tcctacctag ccgttagaaa acggaatttg tttacaaact taattgacag cctcagtatg
     3061 gtaccttata ttgtaccagg aaccgttcta gggattgcct tcatttcttc cttcaatact
     3121 ggtctatttg gaagtggatt tcttatgatt acagggactg ctttcatctt gattatgtct
     3181 ctatctgtca gaagattacc ttatactatt cgctcatctg ttgctagctt acaacaaata
     3241 gcaccaagta ttgaagaagc tgctgaaagc ttaggaagta gtcgtctcaa tacctttgct
     3301 aagattacaa ctccaatgat gctatctggt atcatttctg gagccatctt atcttgggtc
     3361 acaatgattt caaaactctc tacttctatc ctcctctaca atgtcaaaac aagaacaatg
     3421 actgtagcta tttatacaga ggttctcaga ggaaattacg gtgtagccgc agccttgtca
     3481 actatcctga ctgttctaac agtaggttcc ttgctcttgt ttatgaaaat ctctaaaagc
     3541 aatagcatta cactttagtt ttccacatca aaaacagccg aaaggagtgc cctcggctgt
     3601 tttttcttat cttgatattc ttatcaaatc cctagctcat ggcaagcaag tctagactga
     3661 ttaaatagag ccttcttcca tcttctcaca tcctagctct cggtaactac ggtcaccgac
     3721 aacttcaacc ctaaactgac cgtcctcata ttcaagaatc gtcacgctac cattatctag
     3781 accatgcgga tgcatgccat taatcagata aacaatggtt ccaatagtca ttccatggct
     3841 gacaacaagg gcgttacctc caccttgatc ttccatttct tttgcaatca tttcaaagcc
     3901 ttccttgatt cggccactga gtttttccca gccttcagcc caaccagctg tatcgacctc
     3961 taccaagccc tcagccagtt cagcataaga caattggtga acgtggtcca cattaaagat
     4021 acgaggaata atgcccatga aaagatcgcc atcataggct ccatcaaaac taccgaaaca
     4081 ccattctctg atacgcttgt ccatgcgata agggattttc ccctgcaagc caagttcttc
     4141 aaggataatt cccatggtct gaatggtacg accagaatca ctcgaataag cgcgctcaaa
     4201 ctgtagatca gattctcgca aaccgattcc taactcttga atccctcgtt caccttcagc
     4261 agttaaggga gtatcgctcc aaccttgcgc gcgaccaatc gtgttaaaca tggtcttgcc
     4321 atgacgtacc aaatacaatc gtacttttac cattttccgt cctccgtttg cttctattat
     4381 atcatgaatg ataaaataaa agccacccat acaggcgact tttgaaggag attattatga
     4441 aaaagtttag gagttcatta aataaagata ttagatgaaa atcaaattca aactaattca
     4501 gtgttatctg tttcaaataa tattaggagg tctttattta atgattatag tatacacatc
     4561 taatcttaaa tagaacttaa aatttctcct attttcttaa tttttaaaac tatgaattgg
     4621 tgctgggatt tgtccaccgc gagagatgaa gtcgacagac gaagccccat taaccttcat
     4681 aacaggtgca gttcctaata gaccaccaaa ctcaatcata tcgccttctc ttcctttggg
     4741 aatgatacga acagctgttg ttttcatgtt gataacaccg attgctgctt catccgcaat
     4801 catagccgca atggtttcag caggcgtatc ttctgggatg gcaatcatat ccaatccaac
     4861 agaacagata gccgtcatag cttctagttt ttctaaatta agagagccat tttgcactgc
     4921 agcaatcatt ccttcatcct cagaaacagg gataaaggcg ccagataaac caccgacttg
     4981 gttgcaggcc atcactccac cctttttaac ttggtcgttc aagagggcca aggcaaccgt
     5041 cgttccatgc gtgccaactg tttctagccc catttcctca aggacacgtg ccacagagtc
     5101 tccaatcgca ggggttggtg ccaaactcaa gtccacaata ccaaactcca cacccagtct
     5161 ctcactggcc atttgaccaa ccaattgacc gatacgagtg attttaaagg cagttttctt
     5221 aactgtttcg gctactacat caaagctctg tccacgaact ttttccaaag cacgtttcac
     5281 cacaccagga ccagaaactc cgacattgat gataacatct gcttccccaa caccatgaaa
     5341 ggcacccgcc ataaatggat tgtcctcaac agcattagcg aatacaacca acttagccgc
     5401 tcccatatct gaaagatttg ccgtttcctt gataattcgt cccatatctg ccacagccgt
     5461 catattaata ccagacttgg ttgagccgat attgactgac gagcagacct tatccgtctc
     5521 agtcaaagcg cgaggaatgg aattgatgag aatctcatct cccttttgat aacctttttg
     5581 tactaaggca gaaaaaccac caataaagtc cacaccaatc tctttcgcag ccttatcaag
     5641 cgcttttgcc agaaccacgt agtccgtcgc atctgtcgct gccccaatca gagaaatagg
     5701 tgtcaccgat acacgcttat taacgatagg aattcccaac tcagccgcaa tttcatcacc
     5761 aacagctact aaattagccg cctttgtcgt aattttttga tagattttct ccgcagcacg
     5821 attgatatct ggatcgatac agtccaaaag agaaatcccc atggtaatgg ttctaatatc
     5881 gaagttttgc tcctcaatca tggcgatggt ttcagtaact tgtctaatat ccatgatgac
     5941 ctcctagata ttatacatag cttcgaaaat cgctgcactc tgaatattga tttttacatt
     6001 caaagtttgc ccaaaagctt caaattcatt acgaagatag gtaaaatctt gcttttcatc
     6061 actagataca acagccatca tcgtaaaata ttcatccaag acagtttgag agatatcgtc
     6121 aatattcaat cctaattctg caattttacc agaaacacct gcaacaattc cagatttatc
     6181 tttaccaaca acagttataa tggctttcat aagtaaactc caattcttct taaaataaga
     6241 aaccttaaca ttaaacagga ttcttttcaa atagtatagc ataattctaa cgaaaatact
     6301 caaaaacgcc tgcttacgaa gttgttctta agaaaaaaac aatttcgtaa acaagcgtct
     6361 actatcccaa cttatgatga gtgttcccgc taggaccgaa atcctagcgg tagaccagag
     6421 ctagactaag agcacaagac tccatcatca taacactcaa caaaattgat gattttatac
     6481 taattcgatg atcgccattg gcgctgcatc accacgacgt ggttcagttt taaggatacg
     6541 agtgtatcca ccgttacgtt cagcataacg aggtgcgatt tctgagaaca atttttgaag
     6601 tgctgtagta gaagtgtact tatcagttgc ttcatcatag ttttcagatg cgatttcatt
     6661 acgtacgaaa gcagctgctt gacgacgtgc atgcaaatca ccacgtttac ctagagtaat
     6721 cattttttca acagttttac ggatttcttt agcacgagct tcagttgtca cgattgattc
     6781 gttgatcaaa aggtcagttg tcaaatcgcg aagcattgct ttacgttgtg agctagtgcg
     6841 tcctagttta cggtaagcca tgtattcctc ctttatttat cttttaatcc aagacccaaa
     6901 tcaatgagtt tgagtttcac ttcttccaaa ctcttgcgtc caagatttcg tactttcatc
     6961 atctctgctt cagatttttc tgtcaaatca tgcacagtat tgataccggc acgttttaaa
     7021 cagttgtatg aacgcacaga caagtccagt tcctcaatcg tacgatctaa aatacggtcg
     7081 tcagattcag tatcagcttc tttcatcact tcagttgact tagcaatctc agtaagattt
     7141 gtaaacaaat caagatgttc tgtcaaaata cgtgctgaaa gccctaaagc atcttctgga
     7201 ataattgttc catttgtcaa gatttcaagg gttaatttgt cgaaaccatc attgctacct
     7261 acacgagcag gttccacttg atagttgact tttgtaactg gtgtataaat agaatctaca
     7321 gcaagtgttc caactggtgc attatccttt ttattttcat cagcaggtac atatccacga
     7381 ccactgttaa cagtcatagt cgcttttaga gaagaacctt caccaattgt aaagagataa
     7441 tgatctggat ttacaatttc aatatcgcta tctgtcaaaa tgtcaccagc tgttacttca
     7501 gcaggacctt caacatccag ttcgatgatt ttttcgtctt caacgtacga tttcactgca
     7561 attcctttaa tgttcagaat gatttgcatc acgtcttcac gaacacctgg aactgtgtca
     7621 aactcatgta acacaccatc aatgttgata gatgtcacag ctgctcctgg tagagaagct
     7681 agaagtacac gacgaagaga gttaccaaga gttgtaccgt agccacgttc aagtggttcg
     7741 attacaaact tgccataatc tttattttca tcaatttttg ttatatttgg tttttcaaac
     7801 tcgatcattt agttactccc tcttaaacga aaagcagtgt aatgcgatga ttatacacgg
     7861 cgacgttttg gaggacgagc accattgtgt ggcactggag tcacatcacg aattgctgtt
     7921 acttcaagac cagcggcagc aagcgcacga atagctgact cacgaccaga acctggacct
     7981 tttacagtaa cttcaactga tttaagaccg tgttcttgtg cagatttagc agcagcttca
     8041 gaagccattt gagcagcgaa tggtgtagat ttacgagaac ctttgaaacc aagagcacca
     8101 gctgatgacc aagcaattgc attaccatgc acatcagtaa tcataacaat agtgttatta
     8161 aatgtagcgt gaatatgagc aataccagat tcgatattct ttttcacacg acgtttacgt
     8221 gttggtttag ccaagacttt tacctcctat attatttttt cttaccagca atcgcaacag
     8281 ctttaccttt acgagtgcga gcgttgtttt tagtattttg tccacggaca ggaagtccac
     8341 gacggtgacg gataccacgg tatgaaccga tttccatcaa acgtttgatg ttcaagttta
     8401 cttcacgacg aaggtcacct tcaactttga ttgcatccac ttcacgacgg atagcatctt
     8461 cttgatctga tgtaagatca cgtacacgaa catcttctga gattccagca gcagccaaaa
     8521 ttttcttaga tgttgcaagt ccgataccat aaacataagt caatgagatt actacgcgtt
     8581 tgtcatttgg aatatcaact ccagcaatac gagccatgtt ttctcctttc tatcttatcc
     8641 ttgacgttgt ttgtgttttg gatttgctgg gcaaattacc ataacacgac cattacgacg
     8701 aataacttta cagtattcgc aaattggttt gaccgatggt cttactttca tttcttatcc
     8761 ctccaagttt ttcgattatt taaagcggta agtgatacgt ccacgtgtca agtcatatgg
     8821 actcatttcg acagtaacac gatctcccgc taaaatacga atatagtttt tacgaatttt
     8881 accagaaact gttgctaaaa tctgatgtcc attttcaagt tcaaccgtaa acattgcatt
     8941 cggcattgta tcaactactt tgccttcaac ttcaatcaca tcgtcttttg ccacgcaaaa
     9001 gcacctccat aaatttcgat tcgatgcctc tagacacaga gacaacaatt ataagtcaga
     9061 ctatctcagt ataacatttg tagcggattt ttgcaagtgc gaaaaacgct ttatttcaaa
     9121 tttgtcaata cttttt
//
LOCUS       DAVAZT010000071         8984 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVAZT010000071 DAVAZT010000000
VERSION     DAVAZT010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8984
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.071"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            168..854
                     /locus_tag="VQT45_001899"
     CDS             168..854
                     /locus_tag="VQT45_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET2360168.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNQLLMAAISTFEEGKVAAESGVDFVGTTLSGYT
                     PYSPKKDNPDFELVERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPL
                     EIAKKFIEVV"
     gene            855..1787
                     /locus_tag="VQT45_001900"
     CDS             855..1787
                     /locus_tag="VQT45_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2360169.1"
                     /translation="MNQEILKKSKIQLTVEHIQKYWILYLMMIPATVLLILFTYGPMY
                     GIIMAFQDFTVFKGYTGSPFVGLKHFQRLFSDPLFYRLFKNTFMVGVLDFLFFFPAPL
                     IFALILNEVRKVRFKSVVQSISYLPHFIPLVVMVGIIFELFGSYGIINSLLSSLGMEP
                     ISFFTKSEWFLPLYIGSGVWKTIGWGSIIYMGALTNIDSTLYEAADMDGANRWHKMWH
                     VTLPSLRPTVVTLFILNAGGIMQVGFEKVFLMSSPATYEVSDVLSTYVYRQGILNSDF
                     SYSAAVGLFNNIVALLFVLLANKIAKKLGEEGIV"
     gene            1798..2727
                     /locus_tag="VQT45_001901"
     CDS             1798..2727
                     /locus_tag="VQT45_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2360170.1"
                     /translation="MIFSKNTKKSNRDKETFVDYLFIFILIIITLLMLYPLWWVVMTS
                     LSEPVWLSKNVVKLFPLKIDITAYKFIFGDSKLWQAYGNSVLYAALSTIVSVAVCSMY
                     AYPLTIPEIRGKKFWNTLILIPMFFSGGMIPLYIQVANLGLLNTAWALVLPGAVSTYY
                     IILFRTQFKSIPMELRESARIDGASEFRIFWNLVLPLSKVIFMIIALYCIVGSWNSFT
                     PPLLYLNDDTKMPLSIYLRNLVVTNTTDTAELSLSAGNTYYQQIAAQGGGIGMRIAIK
                     MGTIVVSVIPIMMIYPFIQKHFVKGILLGSVKG"
     gene            2741..4180
                     /locus_tag="VQT45_001902"
     CDS             2741..4180
                     /locus_tag="VQT45_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001178946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360171.1"
                     /translation="MQNLKKYLLLDSGLVVGYTLENAQLKLNKLKKDTENNPLFGEEY
                     FAENPKLWEVRFDNSYPNVIYDKELKLYRCWYQTFVSDEASEETPLAERGEKEYIVKS
                     SRMTALCYAESKDGVKWEKPNLNLVKFKGSKDNNIVLMHAHGAGIMLDEQELDPKKRY
                     KLVSKLEFSPNLHYMVVVFSEDGIHFDEPIPWKKWNPAADSHNFPFRDPKTGKYAVIT
                     RTWANNVRLSAITFSDDFINWSEPKEILRGDGFEDQIYSMPVISYADIYLGFASMYHE
                     GDTLNENYDKVDLELKFSANLEQWDSVCKGDYLIERGGGVYPQNADFDASCIFTAAPI
                     IEDDKIWFYYMGGNGNHTGFRESSLARGYIKKDQFAYYTNKREGIPAKISTVSFQTYD
                     DEIYILADIPENGYIKVAVGTKYGNAYSDFGQEDISLVQVSDGKYKLEFNKKSILDLG
                     NSPVAFKFEIENAKLYGIEGSIQQHYLKY"
     gene            4249..5826
                     /locus_tag="VQT45_001903"
     CDS             4249..5826
                     /locus_tag="VQT45_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2360172.1"
                     /translation="MVKLNKVLKGSVAFLSASLLLAACGNNANSKPAEKTADGKTKIS
                     FLSTWQINDVRPPKDETLVGQWLEEQLGIDIDLVTIPGEGVSSKVNSLITSNQLPTVL
                     LTTGDKSDIAGINKLGKQGAFLDLSQHMDKLPNYKKYLEKNNALAQIEDDEKHIYAFT
                     KFFTDENIMYTTPILRKDLLVGSEFEDLSKIKTVDDYTKVLKYLTEKQGSPAFIQRNG
                     YEGFMKRVTPLWNLSHRTYYDYESDSYKHPVEQPQLKQFVEWLKELRKDNVLHPDWAV
                     MKDETWEGLLASNKGSFTVDRMNIIGDNNFDKSFDWQPLVYPEINGKRYLQPKTPYIS
                     DSGWVINANAPKEEIDKALEFFNFLYADENQEKLAIGFEGKTFTRENPNTQAGIKWLI
                     QIYGENAGNDKAELLFKHGNQAFTRVQTKLDIEAQPGTFPKVMYDQVDKIKKDLGGFR
                     PDTPVLSFTTEELDVLTKSEAGLNTFFDENIIKFIEGQRDMSEWDSFINEAKSKDLDK
                     VTKVYNDAYKRVKDRMK"
     gene            5886..7346
                     /locus_tag="VQT45_001904"
     CDS             5886..7346
                     /locus_tag="VQT45_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET2360173.1"
                     /translation="MYDVVIIGAGSSGALAAIASGRLGLKTCLIEKGSRIGGVPINTL
                     MGSFANLYFDDSGRVNASKIVGELIERIIKKGGTVFNSMEELMNVNDFYQITIPYQPE
                     VYESVLTDMLIESKVDILLNVEVNNIIYDSKNIKSLEILSNQEVKLIDSKVFIDATGN
                     ATIASASGADVYEKNSSYGCLMRVGGVDISKTIEHIEKTKQWNYIEGYNQWLEEVLAN
                     RKYRATGAVLKDPVSYDHAPMLSKDDHFMNDEKWNYIKERWEKFRFIYTLEVSLFRNE
                     LKKAVESGDFNFEIYHDDKSGVTMNGDGISYGSWGQNVALINVAKAFGFNPKYMEDES
                     HANILSRKYNLTFLSFLKKYVPGFENSFILDQGTRATNRSCRHIDNSSMMDEILDFPM
                     YTFKTMYSYQTPKEITYKSIVGGKLNNLFVIGKGAYQSESFRSQISCMLMGISSAAAA
                     KTIIEDKSNTLNINRDLFKSNLDILFTWEFSNWITD"
     gene            7368..7823
                     /locus_tag="VQT45_001905"
     CDS             7368..7823
                     /locus_tag="VQT45_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001000318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT domain-containing protein"
                     /protein_id="HET2360174.1"
                     /translation="MNDTNKNQYFVYEFDTSFVEMSYSQFFEGYCILFSKEPYPSLSD
                     MPMEFRKEFLMEMSILGDAMLEVLNAYRINYDILGNSTPVLHAHLFPRYMWEEEERRK
                     TVVHRYDSSVFSNPEFEFTIEKHGPIIKKLRSAIDRHYREYQQLLDDSN"
     gene            7910..8315
                     /gene="cdd"
                     /locus_tag="VQT45_001906"
                     /pseudo
     CDS             7910..8315
                     /gene="cdd"
                     /locus_tag="VQT45_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221146.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
     gene            8328..8777
                     /locus_tag="VQT45_001907"
     CDS             8328..8777
                     /locus_tag="VQT45_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2360175.1"
                     /translation="MELVEFKNGHVNTVHEHIAITKVKEFLNNHDILKDKGGIHKIST
                     DFFYNIIDMETTTEENRPWESHKEYYDVHYLLNGEETILYNFLSQMELSEYKVDDDWQ
                     QMNGTALFSIKLKKDMLLLLEPNDAHRTGLLVEEPLNIKKVVFKVKI"
BASE COUNT         3115 a         1180 c         1679 g         3010 t
ORIGIN      
        1 gtgtattgaa tctataacag tacgccttaa atgctaaaat atttctataa attaatttaa
       61 ctttcctgat agggctgttc atatcttatt tcaattcact atataaataa aattgtagta
      121 gatgttattg aattagtaaa aaaaataaaa aaacggaggt tttctgaatg gaaactaaaa
      181 aaattaaaaa tttaaaaggt caaataattg tttcctgcca agcgttagaa ggagagccac
      241 tttatactcc aaatggagga gtgatgccgt tattagcaaa agccgccttt caagcaggcg
      301 ctaaaggtat tcgtgctaat tctgtccgcg atatttcaga aataaaagaa gaagttgact
      361 taccaattat aggtatcata aaaagagatt acgatggctt tgaacctttt atttcagcaa
      421 ctatgaaaga gattgatgaa ttagttagtg aaggagtaga cattttagct ttggattgta
      481 ctaatcgttc aagaccaggt tatgataata ttactgactt tattcatgat attaaagtca
      541 agtatccaaa ccaattatta atggctgcta tttctacttt tgaagaaggg aaagtagctg
      601 ctgaatcggg agtagatttt gtgggtacga cattatctgg ttatacacca tatagcccta
      661 aaaaagataa tcctgatttt gagttagttg aaagattggt aaaagagctt gacgtaccag
      721 ttattgctga aggaagaata agtactccgg aacaagctag aaaaatgtta gatttaggtg
      781 cttacgcagt ggttgttgga ggagctatca ctcgtccttt ggaaatagcg aagaagttta
      841 ttgaggtagt ttagatgaat caagaaatat taaaaaagag taagattcaa ttgacagttg
      901 aacatattca aaaatattgg attttatatt taatgatgat tccagcaact gttctactaa
      961 ttttatttac gtatggacca atgtacggca ttattatggc ctttcaagac tttactgtct
     1021 tcaagggata tactggaagt ccatttgtcg gtttaaaaca ttttcaaaga ttgttctcag
     1081 atcctttgtt ttatagattg ttcaagaata cgttcatggt aggggtttta gattttttat
     1141 tctttttccc agctccgctt atttttgcac tcatattaaa cgaagtcaga aaagtaagat
     1201 ttaagagtgt agttcaatct attagttatc ttcctcattt tattccccta gtggttatgg
     1261 ttggtattat ttttgaacta tttggttcat atggtattat taacagttta ctttcatcac
     1321 ttggaatgga gccaataagt ttctttacaa aatctgaatg gttcttgcct ctctacattg
     1381 gttcaggagt atggaaaaca ataggttggg gttctatcat ttatatggga gcattaacca
     1441 atatagattc aactttatat gaagcagcag atatggacgg ggctaataga tggcacaaaa
     1501 tgtggcatgt aactctacca agtttaagac ctacagtagt tactttgttt atactaaatg
     1561 ctggtggtat catgcaagta ggatttgaaa aggtattctt gatgtctagt cctgcaacat
     1621 atgaagtatc tgatgtatta tctacttatg tttatagaca aggtatttta aattctgatt
     1681 tcagttactc agctgcagta ggattattta ataacatagt agctttgtta tttgttttat
     1741 tagctaataa gattgctaaa aaacttggcg aagaaggaat tgtataaggg gggtaaaatg
     1801 attttttcaa aaaatacaaa aaagagtaat agagacaaag aaaccttcgt tgattatctc
     1861 tttatattca ttttaataat aataacctta cttatgttgt atccattatg gtgggtagtg
     1921 atgacgtcac tttcagaacc agtttggcta tctaaaaacg ttgttaaatt atttccctta
     1981 aaaatagata ttactgcata taagtttatt tttggggatt ctaaactatg gcaagcatat
     2041 ggtaatagtg tattgtatgc tgcactatct acaattgtta gtgttgcggt atgtagtatg
     2101 tatgcctatc cacttacaat tcctgaaatt aggggtaaaa aattctggaa tactcttatt
     2161 ttgattccaa tgttctttag tggaggaatg atcccgcttt atatacaagt tgcaaacctc
     2221 ggtttattga atactgcttg ggctcttgtt ttacctggtg ctgtttctac atattatata
     2281 attttgttta gaacacagtt taaatcaatc ccaatggagc ttcgtgagtc tgctagaatt
     2341 gatggggcaa gtgaatttag aattttttgg aatttagtat taccattatc aaaagttatt
     2401 ttcatgatta tagcacttta ttgcatagtt ggttcatgga atagttttac tcctccatta
     2461 ctttatttga atgacgacac taagatgcct ttatctattt atttgagaaa tttagtcgtt
     2521 acaaatacaa ctgatactgc tgaattatca ctttctgcag gtaatacata ttaccaacaa
     2581 attgctgctc aaggtggagg tattggtatg cgtattgcta ttaagatggg tactattgtt
     2641 gttagtgtta ttccaattat gatgatttat ccatttattc agaaacattt tgttaaggga
     2701 atcctgctag gttctgtgaa aggttaataa ggtaattatt ttgcaaaatt taaaaaaata
     2761 tcttttatta gatagcggtt tagtagttgg gtatacatta gaaaatgctc aattaaaatt
     2821 aaataagcta aaaaaagata ctgaaaacaa tccactattt ggtgaagagt attttgccga
     2881 aaatcctaaa ttatgggaag ttcgttttga taattcatat ccaaacgtta tctatgataa
     2941 agaattgaaa ttatatagat gttggtatca aacatttgtt agtgatgaag caagcgaaga
     3001 gactccttta gcagaacgtg gagagaagga atacattgtc aagtcatcta gaatgacagc
     3061 actttgctat gctgaaagta aagatggagt aaaatgggaa aaaccaaatc tcaatctagt
     3121 aaaatttaaa ggttcaaaag ataataatat tgttctgatg catgcacacg gtgcaggtat
     3181 catgctagat gaacaggagt tggatcctaa gaaacgatat aaattagttt caaaattaga
     3241 attttctccg aatcttcatt acatggttgt tgttttttca gaagacggta ttcattttga
     3301 cgaacctatt ccatggaaaa aatggaatcc tgcagcagat agtcataatt ttccatttag
     3361 agatccaaaa actggtaaat acgctgttat tacaagaacc tgggcaaata acgtacgtct
     3421 aagtgcaatt actttcagtg atgattttat taattggtca gaacctaaag aaatccttag
     3481 gggagatgga tttgaagatc aaatttattc tatgccagta atttcatacg cggatatcta
     3541 tttaggtttt gcttcaatgt accatgaagg cgacacttta aatgaaaact atgataaagt
     3601 agacttagaa ttgaaattct ctgctaattt ggaacaatgg gatagtgtat gtaagggcga
     3661 ctatctcatt gaaaggggag gtggagtata cccgcagaat gctgattttg atgctagttg
     3721 tattttcacg gctgctccaa taattgaaga tgataagatt tggttctact atatgggtgg
     3781 aaatggtaat cacactggct tccgagaaag ttcattagct agaggatata ttaagaaaga
     3841 ccaatttgct tattatacta ataagagaga aggaattcca gctaaaatat ctacagttag
     3901 cttccaaact tacgatgatg aaatttatat cttagctgat attcctgaaa atggttatat
     3961 taaagttgcg gtaggtacta aatacggtaa tgcttattca gatttcggtc aggaagatat
     4021 ctctcttgtt caagtttccg atggtaagta taagttggaa tttaataaaa aatctatctt
     4081 agatttaggt aattctccag ttgcgttcaa atttgaaatc gagaatgcaa aattgtatgg
     4141 tattgaaggt agtattcagc aacactatct caaatattaa ccagaataat tcgttaacaa
     4201 ataatctcta tattagtgga gatagatata taaaatggag gtcttattat ggtaaagctt
     4261 aataaggtat taaaagggag tgttgcattc ctgagtgcaa gtttattgct agcagcttgt
     4321 ggcaataacg ctaattcaaa gcccgctgaa aaaacagctg atggtaaaac gaaaatttcg
     4381 tttctatcta catggcaaat taatgatgtt cgtccgccta aagatgaaac acttgttggt
     4441 caatggttag aagaacagct aggtattgat attgatcttg taactattcc tggcgaggga
     4501 gtaagttcta aagtaaattc tcttattact agtaaccagt taccgactgt tttgttgaca
     4561 acaggagata agagtgatat cgctggtatc aacaaacttg gtaaacaggg tgcattctta
     4621 gatttgtcac aacacatgga caaactacca aactataaga agtaccttga aaaaaataat
     4681 gcattagctc aaatagaaga tgatgaaaaa catatttatg ctttcacaaa attctttact
     4741 gatgagaata tcatgtatac tacaccaatt ctgagaaaag acttacttgt tggttcagaa
     4801 tttgaagatc tttcaaaaat taaaactgtt gatgactata caaaagtttt gaaatatttg
     4861 actgaaaaac aaggttctcc agcatttatt caacgtaatg gctatgaagg cttcatgaag
     4921 cgagttacac cattgtggaa tttaagccat cgtacatact atgactatga atcagattca
     4981 tataaacatc cagttgaaca acctcaattg aaacaattcg ttgaatggtt gaaagaatta
     5041 cgtaaagata acgtacttca ccctgactgg gcagttatga aagatgaaac ttgggaaggt
     5101 ctattggctt ctaacaaggg ttcattcact gttgaccgta tgaatatcat tggagataat
     5161 aactttgata aatcatttga ttggcagcca cttgtttatc cagaaattaa tggaaaacgt
     5221 tatttgcaac cgaaaacacc gtacatttct gattcaggtt gggtaatcaa tgccaatgca
     5281 ccaaaagaag aaattgataa agcgttagaa ttctttaatt tcttatacgc tgatgaaaat
     5341 caagaaaaac ttgctattgg atttgaaggt aaaacattta cacgtgaaaa ccctaatact
     5401 caagcaggta ttaaatggtt gattcaaatt tacggtgaaa atgctggaaa tgataaagca
     5461 gaactgctgt ttaaacatgg taaccaagca tttactcgcg ttcaaactaa attagatatt
     5521 gaggcacagc caggaacatt ccctaaagtt atgtatgatc aagtagataa aattaagaaa
     5581 gatttaggtg gttttagacc agatactccg gttctttcct ttacaactga agaattagat
     5641 gttttaacta aatctgaagc aggattaaat actttctttg atgaaaatat tattaaattc
     5701 attgaaggac aaagagatat gagtgagtgg gattcattta tcaatgaagc taaatctaaa
     5761 gacttggata aagttacaaa agtatataat gatgcctaca aacgtgtcaa agatagaatg
     5821 aaatagacta aatggtagct ctctggtttt tcagagagct actactgcct gagggggagt
     5881 aagctttgta tgatgtagta attataggtg caggaagttc gggcgcattg gctgcaattg
     5941 cttcggggcg tctagggtta aaaacttgtc taatagagaa gggaagtaga attggtggag
     6001 ttcctattaa tacactaatg gggtcatttg ctaatctata ttttgatgat tctggtagag
     6061 taaatgcaag taaaattgtt ggggaattaa tagaacgtat tatcaaaaaa ggtggtactg
     6121 tctttaactc tatggaagaa ttgatgaatg taaatgattt ttatcagatt acaattccct
     6181 atcaaccaga agtttatgaa tcggttttaa ctgatatgtt gattgagtct aaagttgata
     6241 ttttactaaa tgttgaagtt aataatatta tttatgatag taaaaatatt aaaagtcttg
     6301 aaattttaag taatcaggaa gttaaattga ttgattctaa agtttttatt gatgctacag
     6361 ggaatgcaac aattgcttct gctagtggag ctgatgttta tgaaaaaaat tcttcttacg
     6421 gttgtttaat gagagttgga ggagttgata tctcaaagac tatagaacat attgaaaaaa
     6481 caaagcagtg gaactatata gaaggatata atcagtggtt agaagaagta ttagcaaatc
     6541 gaaagtacag agccactgga gcagttttaa aagatccagt ttcttatgat catgccccta
     6601 tgctttcaaa agacgaccat tttatgaatg atgaaaaatg gaattacatt aaagaaagat
     6661 gggaaaaatt tagatttatt tacactttag aagtatcact atttaggaat gaattaaaaa
     6721 aagctgtaga atctggggat tttaattttg aaatttatca tgatgataaa tctggagtca
     6781 ctatgaatgg cgacggtata agctatggtt catggggtca aaatgtagca ttaattaatg
     6841 ttgcaaaagc atttggattc aatcccaaat atatggaaga tgaatcacat gctaatattc
     6901 tttctagaaa atataattta acatttttat cttttcttaa aaaatatgta ccaggttttg
     6961 aaaattcttt tatccttgat cagggaacta gagctactaa cagatcatgt aggcacattg
     7021 ataattcatc tatgatggac gaaattcttg attttccaat gtatacattt aagactatgt
     7081 atagctatca aactcctaaa gaaataacgt acaaatcaat tgtaggtgga aaattgaata
     7141 atttgtttgt aataggtaaa ggtgcttacc aatccgaaag ttttagatca caaattagtt
     7201 gtatgttaat ggggatatca tcagcagcag cggcaaaaac tattattgaa gataaaagca
     7261 atactctaaa cattaataga gatttgttta aatcgaactt agatatatta tttacatggg
     7321 agttttctaa ttggattact gattaacaaa taataaggga atattaaatg aatgatacta
     7381 ataaaaatca atactttgtt tatgaatttg atactagctt tgtagaaatg tcttattctc
     7441 agttttttga aggatattgt attctttttt caaaagaacc ctatccttct ttatctgata
     7501 tgccaatgga atttagaaaa gaatttttaa tggaaatgag tatattaggt gatgcgatgc
     7561 ttgaagtgtt aaatgcctat agaattaatt atgatatctt aggaaattca acacctgtac
     7621 ttcatgctca tttatttccg agatacatgt gggaagagga agagagaaga aaaactgtag
     7681 ttcatagata tgattcttca gtttttagca atcctgagtt tgaatttact atagaaaagc
     7741 atggaccaat tattaaaaaa ctgaggtctg ctattgatag acattataga gagtatcaac
     7801 aattattaga tgattcaaac tgaactccac attttcgatt agatttaata ccttgtatat
     7861 tacaactagg ttgtggatga tataattttt tgaaaaatat attttaggaa tgacttataa
     7921 agcaattata tcagaggcta ttaaatcaat ggccaaagct tatgctcctt attctgattt
     7981 taaggttgga gctgcgttag taactgaaga taaaaaattt tttctggatg taatatagaa
     8041 aatgctgctt tttctcctac ttgctgtgca gaacgagtat ctttttataa agctgtattt
     8101 aaaggagaac gttcgttttc aagaacatgt attgtaggtg gaaaaaatgg tatcttatca
     8161 tcttttatag caccttgcgg agtgtgtcgc caggtaatga tagaatttgt aatcctgatt
     8221 catttgaagt tatattggct agtgatgttg atacttataa agtatataaa cttaaagaac
     8281 tactaccagt tagttttaat caagaaaatt tataacagga gggaactatg gaattagttg
     8341 aatttaaaaa tggacatgtt aatacggttc atgagcatat cgcaataacg aaagtaaaag
     8401 agtttctaaa taatcatgat atattaaaag ataaaggtgg catacataaa atttctactg
     8461 atttctttta caatataatt gatatggaaa ctacaactga agagaataga ccgtgggaaa
     8521 gtcataagga atattatgat gtccattatc tgttaaatgg agaagaaaca attttatata
     8581 acttcttgtc tcaaatggaa ttgtctgaat ataaagtaga tgatgattgg caacaaatga
     8641 atgggacagc tttatttagt attaaattaa agaaagatat gttacttttg ttggaaccaa
     8701 acgatgcaca tagaacaggc ctattggttg aagaaccact taatattaag aaagttgttt
     8761 ttaaggtaaa aatttaactg aaagtacttt cggggattaa gaattttaaa atatttaaga
     8821 aattgtattc taaagttcta aaattataga tatttaattt aaagcttgtt aaaatagaat
     8881 agtaacactc atctgctttc aaaaagcatt ctattccatc tccgattaac gatggacttt
     8941 atcacctcct tctccagtcc ttgtatgaca tcttggagtt gatt
//
LOCUS       DAVAZT010000072         8844 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVAZT010000072 DAVAZT010000000
VERSION     DAVAZT010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8844
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.072"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(135..1103)
                     /locus_tag="VQT45_001908"
     CDS             complement(135..1103)
                     /locus_tag="VQT45_001908"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET2360176.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(1248..2063)
                     /locus_tag="VQT45_001909"
     CDS             complement(1248..2063)
                     /locus_tag="VQT45_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HET2360177.1"
                     /translation="MKKSSILFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKKWELPKKVLILSLLGGMFLSGWLSSFTNTYIHDLLGVLFPD
                     SPFLNAFESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIG
                     YIRTDLPEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAHKEQKVGKKQGLI
                     FLGLALRTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            complement(2088..2585)
                     /locus_tag="VQT45_001910"
     CDS             complement(2088..2585)
                     /locus_tag="VQT45_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HET2360178.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(2658..4019)
                     /gene="radA"
                     /locus_tag="VQT45_001911"
     CDS             complement(2658..4019)
                     /gene="radA"
                     /locus_tag="VQT45_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HET2360179.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MSVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(4033..4548)
                     /locus_tag="VQT45_001912"
     CDS             complement(4033..4548)
                     /locus_tag="VQT45_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET2360180.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGFPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(4550..4993)
                     /locus_tag="VQT45_001913"
     CDS             complement(4550..4993)
                     /locus_tag="VQT45_001913"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HET2360181.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(5050..5147)
                     /gene="ffs"
                     /locus_tag="VQT45_001914"
     ncRNA           complement(5050..5147)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VQT45_001914"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5180..5647)
                     /locus_tag="VQT45_001915"
     CDS             complement(5180..5647)
                     /locus_tag="VQT45_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HET2360182.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(5848..7134)
                     /locus_tag="VQT45_001916"
     CDS             complement(5848..7134)
                     /locus_tag="VQT45_001916"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HET2360183.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGIGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGARNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(7365..7601)
                     /locus_tag="VQT45_001917"
     CDS             complement(7365..7601)
                     /locus_tag="VQT45_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HET2360184.1"
                     /translation="MLQKIYEQMTNFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            7867..8664
                     /locus_tag="VQT45_001918"
                     /pseudo
     CDS             7867..8664
                     /locus_tag="VQT45_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8699..>8844)
                     /locus_tag="VQT45_001919"
     CDS             complement(8699..>8844)
                     /locus_tag="VQT45_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2360185.1"
                     /translation="KLLPLPPYSPEYNPIEKTWAYIKKNLKKVLPSCNTFYEALFSCS
                     CFN"
BASE COUNT         2836 a         2104 c         1425 g         2479 t
ORIGIN      
        1 tgatgacgta cagtcatatt tcttctcttt ttattatatc acagttttaa atctagcttt
       61 actagattca ccgctactat ctatttattc ggaaaaaaga cgaaaaaacc tgagaatcat
      121 ctcaggcttg gtcattaaat ttttttctca atatcgaaaa gtggagaaag tggtcgtttt
      181 tcatgaatac gtacgatagc atcccctagg agatgagcga ttgaaatctg ctcaatctta
      241 tcaatcaaac gctcttctgg cagatagatg gtatccaaaa caaccaattt cttaatagct
      301 gatttttgga tattgtccgt agcaggacca gaaagaactg ggtgcgtaca gcttgcatag
      361 acttcaacag caccagcttc cgcaagagca tctgccgcat gacaaatcgt tccagcggta
      421 tcaatcatat catcaatcaa gatacaagtc ttgccttcaa ccttaccgat gatgttcata
      481 acttcactag tattcatctt atcaacgcta cgacgtttat caataatagc gatagatgtt
      541 ttcaaaaatt ctgccaactt acgagcacga gtcacccctc catggtccgg gctgacaacc
      601 acatagtcag aaccaaccat accacgacgc tcaaaataat ctgcaatcag aggagcaccc
      661 atcaaatgat ccacaggaat atcaaagaat ccttgaattt gcgcagcatg caagtcgatg
      721 gtcaataaac gatccactcc agctacttca agcatatttg cgacaagttt tgaagtgatt
      781 ggctcacgcg ctctcgcctt tctatcctga cgtgcatacc catagtaagg catgacaaca
      841 ttgacagatt ctgcactcgc acgcttcaaa gcatctacca taatcaaaat ttcaagcaga
      901 ttgtcattta caggcgaact agttgattgt aggataaaga cgtgtttccc acggattgat
      961 tcttcaatgt tgacctgaat ctctccatct gaaaattggc gaacacttga tttccccaac
     1021 tctatcccaa tctcctgcgc cacacgttct gccaattctt tattagaaga aagggcaaac
     1081 agctttaaat cagaaaaaga catgatttcc tccggtatat atgtatcgct tgtgcttttc
     1141 acaagatttt ccatctacca ttgtagcgct ttttgcacta tttttcaatc aaaaataaaa
     1201 gaagggcacc atatttgtac ccttgcatca ttcttttgaa aaatattcta ggtcatcaac
     1261 tcattgtgtt tctcaacaaa gcaataagca tgataaaaac catagagagc aatagccgta
     1321 accactggaa tcgctaaagg caactctgtt tccaactcca caaaaggaga gttaaacaag
     1381 aagtgagttc tcaaggctaa acctagaaaa ataaggccct gtttcttgcc aaccttctgt
     1441 tctttatggg ctctgtaaag caagtaaaca cctactacag ctagacctga aaaagtccag
     1501 tgagaggcaa ttcctgagat gatacgctct aaaattcgcg aaatagtaaa gtcaaagccc
     1561 tctggcaaat ccgtacgaat ataaccaata tcctcaatca tttggaatcc caaaccggaa
     1621 gcaattccaa gtaaaaacaa agattttaat tttcgcacag gaatcaaagc caaaacaaaa
     1681 acaagtggca ataatttcaa gggttcttct accaaaggag ccacaatagc actttcaaag
     1741 gcatttaaaa atggactatc tgggaaaaga acccccagta aatcatggat ataagtatta
     1801 gtaaaactag acaaccagcc tgaaaggaac atccctccca ataaagacag aatcaaaacc
     1861 ttctttggca attcccattt tttcccaata cggaagagaa aataaagagc cggaatcatg
     1921 taaaagagag ctagaaagat agaaactccc attagtccat attccgcacc tgacctcgaa
     1981 ccgtccgtat agtagatggt ttcatactgt aaaccaatac atagcaataa aataaaaata
     2041 aataaaatac tgcttttctt catacacttt ctttctaaat gaagtattta taattctacg
     2101 actgtcatac ttcctgtatc aacattgtaa atggcaccag agataatgac atcgtctggt
     2161 attaggggag actcgataag cagttgcata tcctcgcgta cactctcttc tatatcttgg
     2221 aagggcaaga agtcctggtc tgacacatct acacctaatt cctcttttaa atactcctga
     2281 aaaggttcat tttcaaaggt ctgagcacca cagtctgtat ggtgcaatac cacaatctct
     2341 cttgtcccca tttgttgctg ggaaataact agcgaacgaa tcatgtcttc agtcactcga
     2401 ccacctgcat tccgcaagat atgagcatcc ccaagtgcca agcccagagc ttgcgcaacg
     2461 tgcagacgag agtccataca ggtcacaata gctactcttg ttttgggttt aagtggcaga
     2521 tttaactgcc catgtagggc aacataagcc tgattagctt gcataaactg ttcaaaatac
     2581 gacacgattc cctccttgaa aatttgatag tcaaatattt ctcctatctt atcattttta
     2641 agagaatttg tcacggatta tgcaaagacc tttttcaaaa cttcctgaat cgttgtcacg
     2701 ccaatgacct gaatttcctt aggcagagtg attcctgtca aggaattctt aggtacataa
     2761 atcttagtaa agcccagttt agcagcttcg ttgatgcgtt gctcaatacg attcacgcgc
     2821 cgaatctctc ctgtcaagcc cagttctccg acaaaacatt cctgaggatt agttggcttg
     2881 tctttgtagc tcgaagcaat agcaactgca acagccaagt caatggcagg ttcatccaat
     2941 ttaacaccac cagcagattt gagataggca tcctgatttt gcaagagaag ccctgcccgt
     3001 ttttccaaaa cagacataat caagctagca cggttaaaat caagtcctgt cgtagtacgc
     3061 ttggcatttc caaacatggt cggtgttacc aaagcctgaa cctccgccaa aatcggacgc
     3121 gtcccttcca tggttacaac gatggaggaa ccagtcgccc catccaaacg ctcttctagg
     3181 aaaacttgac tcggattgag tacctcaacc aagccgcccg actgcatctc aaaaatccca
     3241 atctcattag tggaaccaaa acgatttttg accgctctca aaatacgaaa ggtgtggtga
     3301 cgctcccctt caaagtaaag caccgtatcc accatatgct ccaacatacg aggcccagcc
     3361 aaggttcctt ctttggtcac atgacctacg ataaagatgg caatgttatt ggtcttggcc
     3421 aactgcatga gttcagcggt cacttcacgc acctgagaaa cagacccctg cacccctgaa
     3481 atctcaggag acatgatggt ctggatggaa tcaataatga gaaagtctgg ctggatacgc
     3541 tccacttctg cacgaacact ctgcatattg gtctctgcat agagataaaa ctcactatca
     3601 atatcaccta agcgctctgc acgtagttta atctgctggg cagactcctc cccactgaca
     3661 tagagaactg tccccacttg ggacaactgg gttgagactt gtaggagaag agttgatttc
     3721 ccaatcccag gatccccacc gatgaggacg agacttcctg gtaccactcc gcctccaagc
     3781 acacggttga attcctccat ctccgtcttg gttcgattga cattgatgga agtcacctca
     3841 gctagtttca tgggcttggt tttctcacct gtcaaggaca cacgcgcatt cttgacctcg
     3901 gcaacctcaa cctcttccac aaaagaagac caagacccac agttggggca acgtcccaga
     3961 tatttagggg aattataccc acaattttga catacaaatg tcgctttttt ctttgcgatg
     4021 acaaacctct ttctatatct ctaactcaca ctcaatcact tggcaaaaat caatcttctc
     4081 atttggcaca aactggcgca tgagcattcg atgagcaaca actaccacag tctgatgttc
     4141 tcgatactta gacatacatt ctagaaaccg agacttcatt tccgtagctg tctcatattg
     4201 aataggacta ttaggaagca actccccctt gttttctaaa aacagtcttc tagctgtttc
     4261 aaagttttct attcctgttt tatagacctg ccattcatgt aataaaggct ctactcttaa
     4321 aggaaaaccc gtagcacata ccacatacga agccgtttct aaagctcttg tgactgcaga
     4381 agatacgatt atttcagctg acgagagtaa aggatttttg ctcaatttct ggacttgctg
     4441 ccgtcccatc tcagacaagg gtgccaaatc tatcccaaat cctatataag aacgctcctc
     4501 taactcacgg taatctggct ccccatgacg tacaaagata atcttcattc tagtgccctg
     4561 tcgatccaaa tccaccagtt cgaacgccat cagccgcatc tccatctgca attaagaaag
     4621 tagcaaaaac agcctggaca atacgctccc caacttcaag aacaacctct tggtctgtga
     4681 tattcttcat ctgcgcaaaa atatgccctt catttccagg atttccataa taatccccat
     4741 caatgactcc aactgagtta attaaaacca agcccttctt acgaggattt gaagaacgat
     4801 catagaggta gagaacctca gtcggctgca tataagcctt aacccctgtc ggaaccaaga
     4861 caatctctcc tggcgcaaca actgtacgca cagcaacctt taagtcgtaa ccagccgcat
     4921 gcgctgtctc acgcttgggc aataaatttt catctgtaaa actcgaaacc aattcaaaac
     4981 cacgaatttt cataattttc tcttttctat tatcatttat tctagattat tctatcttat
     5041 ttattcggaa aaagcacgaa aaaaagagca cacaattcaa atcgcttagg gctgctggat
     5101 tcctcccctg acccgcttca cgcagaactg ttgctccact atttattata tcacattcct
     5161 attcatttta aaagcaaaat tattttttcc gtctatttct aaaaaaatcc tgcatgatag
     5221 ctgcgcattc atcttccaaa attcctattt caacctccac acgatgatta agacgctcat
     5281 ctgtcaagat atcgtacaaa cttccagcag cgccaaattt ctggttttta gccccataga
     5341 ccacatttgg aatgcgggca agcccaatcg ccccactaca catgacacaa ggttcaatgg
     5401 tcacaaaaag tgtgcaatcc agcaagcgcc agctctcctc actcaagttc gcatcctcta
     5461 tagccataat ttccgcatgc ataaccgctc gctgtaattc ctcacgcgca ttatgcccac
     5521 gaccaatgat ttccccatct ttgacaatca cacaaccaat tggaatttca tcgtgttcaa
     5581 gagcaatctc agcctctctc aaagcctccc tcataaagac ttctttttct tcaagcgtat
     5641 aatacatctc ttttctcttt tcctacttat cgattttatt attatatcat gaatcccaac
     5701 acaaaaaaag ccaccgaatg cggtgactct atagggagat tattatgaaa aagaaaagtt
     5761 taggatattt gttacaacaa gttaggaggt cttcttgtaa ctgtctatag tatacccgac
     5821 ctatcttaaa caaatcttaa aaatctctta ggaccaaaca ctttctaaaa tatttgtttg
     5881 ttcacgacca ggacctactg agaaagtaga aatacgaacg ccaaccaatt cactcacacg
     5941 acgaacatag ttacgcgcat tctcaggaag atcttccaaa ttgcgagctc cggtaatatc
     6001 ttctgaccaa cctggcaact cttcatagat aggcttgcaa cgtttcaatt gctcaagact
     6061 agctggatag tagtcaatac gttgaccgtc aagatcatag gccacacaaa ttttcacagt
     6121 atccaagccg ctcaaaacat caatagagtt caaagaaagg ttagtaatac cagaaacacg
     6181 acggctatga cgcatcacaa ctgagtcaaa ccaacctaca cgacgtggac gaccagttgt
     6241 tgtaccatat tcatgaccca cttcacggat acgttctccc acttcatcaa acaactcagt
     6301 tgggaaagga ccatctccta cacgactcgt ataagcttta catacaccta caaccttgtc
     6361 aatcttgctt ggaccgatac cagaaccaat tgtcacacca ccagctacag ggtttgatga
     6421 cgtaacaaat ggataagtac cttgatcgat atctagcata acaccttgtg caccttcaaa
     6481 aagcacacgt ttgccattat caagcgcatc attcaagata acagatgtat ctatcacgta
     6541 tttcttgatt tgttgaccat attcgtaata ttcttcaaaa atatcatcga aaacaatcgc
     6601 tttactgtca tacaattttt caaaaagacg attcttttca gcaaggttac gttctaaacg
     6661 ctcacggaaa atatctttat ctaaaagatc tgcaatacga attccaacac gagcagcctt
     6721 gtccatataa gctggaccaa ttcccttaat tgtcgtacca atcttattgt cgcccttagc
     6781 ttcttcttgc aagcgatcca actcgatatg ataaggcaaa ataacatgcg cacgatcaga
     6841 aatacgcaag ttatcagttg ttacaccttc ctcatgaaga tagctcaact cttttacaag
     6901 agatttagga tttacaacca taccattccc aatgacagat attttttcag ggaagaaaat
     6961 cccagatgga atcaagtgca acttaaattt cttaccgtca atcacaatcg tgtgaccagc
     7021 attatcacca ccttggtaac gtgcaattac ttctgcattc gctgaaagga agtctgtaat
     7081 cttcccttta ccttcatcac cccattgggt acctacaaca acaactgaag tcataatttt
     7141 gtctgagccc tcaggctctt cctttctcac atacatggca ggactctcac ctgcaattat
     7201 atcttacaat ttattataat aaaaaatcgc ctttttatca agaagaaaca atagaaagat
     7261 ttgctatttc caactattaa aaaatgattt agaaaaatta ctagctattt actattatct
     7321 ttccataaaa gagtaaatta gttcggaaat ttactaaaat tacctcaaca agaaataaaa
     7381 ccccgattca ttaccaattt ttcaagatac aaacgataag caacacgata atggtaaacg
     7441 ataaaatccc tacgacaacc aatgccatat ctcactaaat aataaattaa aaatttaaaa
     7501 tgaacatgtt cccagtcaaa attatcacca aatgtaggac catactcttc ttcaatacta
     7561 tcatagaaat tagtcatctg ctcataaatt ttttgtaaca taatcaaata ctccttttct
     7621 tttttataaa cttattctaa caaaaaattt tacacattca ctatcaattc ctgaattgtt
     7681 aaaataccag cctcaacaag ataaaaatag gaaaagttga caaaatagaa acaaatttgc
     7741 tacctaaatt tcaaacgatt aaagttctaa aaagaccgcc ttaaaacttt tgggtaaatc
     7801 ctattagaac tataatattt atatatatgt attatggttc tgattttcta gtataaaaaa
     7861 attcaaacta gaattcttct tagaaaaggc cgttttaagt gctatcattg ctcaaaaatg
     7921 gaggtcgctg agacttctat cgtcaagaag aatcatcaaa ttccttgtat catcaaccaa
     7981 aagattgctc agaagttaat tgaaaagact tctatgaccg acattgatca tcagttgtct
     8041 atttcaactt caactgtcat tcgcaagatc aataattttc actttgagca tgatttttcg
     8101 cgtcttcctg agattatgtc ctaggacgtt gaaacagtcc ggggagtgac tgtttcaatc
     8161 gggagatgga gatgagcttt attgctcagg actttgataa actcaatatc ataactgttc
     8221 ttgagagcag aacacaagcc atcatccgaa atcccatgaa tacaaggcta tcaagcgcta
     8281 ctggaagctc attcaacaag atagtcagaa actgagtgat aaacgatttt atcgccctac
     8341 ttttcgtatg cacttgacta ataaagaaat tctagataaa cttttgagct attccgaaga
     8401 cttgaaacac cactataatc tctatcagct cttgcttttc cacctctgtt tcagactttg
     8461 tttaaaacct tcctcaaaga taaagagaaa atcgtcaacg cccttcaatt accttattcc
     8521 aacgccaaac tggaagccac caataatctc atcaaactta tcaagcacaa tgcctttggt
     8581 tttaggaact ttgaaaactt caaaaaagaa aggacgaaat ttgtcctttc tagatcttcg
     8641 ctttcttcaa cccactacag ttgacaaaga accgaaaaat gtctcgcctc taatatagtc
     8701 aattgaaaca agaacaagag aaaagagcct cgtaaaaggt attgcaactt ggtaatacct
     8761 ttttgaggtt ctttttgata taagcccatg ttttctcaat aggattgtac tcaggtgagt
     8821 agggaggaag aggtaaaagt ttat
//
LOCUS       DAVAZT010000073         8559 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVAZT010000073 DAVAZT010000000
VERSION     DAVAZT010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8559)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8559)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8559
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.073"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            221..2830
                     /locus_tag="VQT45_001920"
     CDS             221..2830
                     /locus_tag="VQT45_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HET2360186.1"
                     /translation="MDYNFNLEHPFFFTNNDYSTDTSIKYQVSLPFNWHEVMNNDEWV
                     YQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICHEMRIPFKHLSTEDKFIMRNGK
                     LVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGPYILSDKRWDEAPIYLRYGVFR
                     PSRDDEKKVAIDELIVGDEVVKDERLPVFKIPKGIVPPDFLNKWLDKKDKKQGDFPFI
                     IDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLGFDGTYSSEKLASECKALKILN
                     EWSETPKIYWHGKIWEHTFLGIEHMKGVPLNRWVTNNFPLYEVVDKTKDYLLRVSKIV
                     EKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIIDWEQAVFSNDEKVVHKVAAPGF
                     RAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNYVSQTRIEGKKLFESLGYTREH
                     IDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIESEQDIQDFIIKLLRGFTLTYG
                     QWRKEFQSRFFPVHYYGLNFNQGIAFSDLAILWSYQQLAKKVKNFKFDDYYEIRTQVI
                     NEAVNNFKKSSLSGLFDGKIGTIWLIYEFGEIDRAVELFTTHFIEIFENSQNKNLYSG
                     QAGILLVGLYFLSKGEIDNKLGEEILIRLREYTLNYIENPETFCKVGASDVQSNDPYE
                     NFGGLLYGHAGVAWLFGEAYKLTGESIYKNGLELAVDKELVAYKVDSNNSLQYSQGHR
                     LLPYLATGSAGLLLLINRNKEILSSKYLKYLTSLERATDVVFCVLPGLFNGFCGLEVA
                     NNIYSDIDDNFSGQKKLIEQLYRYLCVIEEGFVIAGDNGLKITTDIASGFAGVAIGLV
                     SIMDNKLTILPQI"
     gene            2863..4803
                     /locus_tag="VQT45_001921"
     CDS             2863..4803
                     /locus_tag="VQT45_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HET2360187.1"
                     /translation="MNQSNEIFLNTIQEKTHYKRSISSSFQELKKWNSLIFRRGRYWY
                     QFDNWSIPNTGVIKEWYVEDNDWIPKVSSSSLDNSNSLKIVFDVEKYTLPDDSILQDV
                     RISSDESYIVLVVSSLRSTNLIGIKKYTMEELFIIEDISVESSFYLGKFGVMYTRSKE
                     YGRPSKLFYKSFDSFTEEELFEENECSFRLKIVHIDSNNCFVKSVDFQKGRIFLYSFD
                     RTGFVRHSYTETVAPTPRDIALFSTEKAQYFLGLSSTEEKKDQLILRETSSGDRVSIT
                     IPYQDRARRVHCIGRYILLDCSNAANSVFYLATFKNNSLRELSVNKITFDEKTTLYEN
                     SFSDRVLLFLERRTFYEKILSFDLIENTLKTEFERPIIKSNNTKYFSKVIWTKKDSYD
                     VSIPISLFWKSEDTDELPRRKKCILSVYGAYGKNDNSDLDEIMLSIIDAGFIYAIVHV
                     RGGGYLGGEWYRSGKALNKWNSIRDFIEGVNYLRENDVIDSKRLGLITSSAGGIIAGA
                     VLNEEKNLLQSILLFSPFINPYDTLQNPNDPLSKTEIAEWGDIRDPEVKAYIKSYSPM
                     QNIEKARDSNTVIVNILGEKDPYINNNEVIEWSKKLNSIGVKSLLYLNKAAGHGGFTP
                     SDVLLMIDTLNYFFEEVGRNNL"
     gene            4800..6407
                     /locus_tag="VQT45_001922"
     CDS             4800..6407
                     /locus_tag="VQT45_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2360188.1"
                     /translation="MNYLKFIKKTKLILMGILIFLSSFNGVLLSGIIVYAGSLNQTSS
                     FSDVLRFGAISILGWSAIYISNYYLEVTEASITKDINVKIKQGYFREQYLSSEMVKDY
                     SSIISVLSNDLRLIEENYFRQIFEIISSILLFIVSLSFMLYLNFLVSIIFIVLSALPI
                     IVPVFMKKMLSNSANEYSNSNAEYTHIIKEIFNGFKTLKSYSVTKEIISLSDKKLDKL
                     EDSTFNLKRSEVLSKLVAVLISGFCFLVPLVVGCYFVIYHKSLSFSELIGIFLANDKV
                     LGPIQSIAYSLNKINTTKDLRKPFLKYLSGEKNFIDAEHDNNGLYTSSIDEIHMKDVV
                     YSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLINGSLKPQKGYVNLLSHGKKS
                     SDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVLKKVNLYEELEKIDILNYQC
                     GENGSNLSGGQKQKIALARALIRNNKVYLFDEISANLDNDNSNSIHDILFNLGISFIE
                     VSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            6422..7162
                     /locus_tag="VQT45_001923"
     CDS             6422..7162
                     /locus_tag="VQT45_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2360189.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            7165..8484
                     /locus_tag="VQT45_001924"
     CDS             7165..8484
                     /locus_tag="VQT45_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360190.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASLLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIASKWNLLYRKPY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     SLEDVLIDDMNLLGLILPNFIVSIILFILIFITKSSYFIFKNAKIIS"
BASE COUNT         2949 a         1060 c         1602 g         2948 t
ORIGIN      
        1 cgttgcggta actggagtgc ttttagttgg gaaaattgtt aattcattta aattgtaaac
       61 tttagagatt ctctggagtt atggatgtcg ttccaatatg tgcacgttgg aatgttagtg
      121 cttatatggg gagaatccaa aggattctcc ctttttattt aaataagtct gtctagctat
      181 agatatatta agtttgataa aatttcttgg agattttgtt atggattata atttcaattt
      241 ggagcatcct ttctttttca ctaataatga ttatagtaca gatactagca taaagtacca
      301 agtaagtctg ccttttaatt ggcacgaagt aatgaataat gatgagtggg tttatcaata
      361 ccctattgga aaatttgttg aaagacaagg gtggaaaata cacattagtt cagagtataa
      421 cagttcacat gaattgttac aagatgtagc aaaaatttgc catgaaatgc gaattccatt
      481 taaacatctt agtacagaag acaaatttat catgcgaaac gggaaattgg ttagtcgagg
      541 attttctggt aaatttatta catgttatcc aaatcaaaat gaattagagt cggttttgca
      601 aaggttagaa agtgccttaa agcaatataa tgggccatat attttaagcg ataaacgttg
      661 ggatgaagca ccaatatatc tgaggtatgg tgtgtttagg ccgtcaaggg atgatgaaaa
      721 gaaggttgct attgatgaat taattgttgg cgatgaagtt gttaaagatg aacgtttacc
      781 agtatttaaa attccaaaag gtatagtgcc ccctgacttt ttgaataaat ggcttgacaa
      841 gaaagataaa aaacagggag actttccctt tattatagat aatgcaatta gattttcaaa
      901 cagtggtggg atatataatg ctaggctaaa agaagatggg aaaaaaataa ttttaaaaga
      961 ggctagaccg tatacaggtc taggatttga tggtacttat tcttcagaga aattagcttc
     1021 ggagtgcaaa gcactaaaaa ttctaaatga atggagtgag acgcctaaaa tatactggca
     1081 cggtaagatc tgggagcaca ccttcttagg aattgaacat atgaagggcg ttccactaaa
     1141 tagatgggtt accaataatt ttcctttata tgaagttgtt gataagacca aagattatct
     1201 attgagagtt tcaaagatag tagaaaaact catcgattta acgaataagt ttcattctga
     1261 aaatgtatat catcaagatt tacatttagg aaatatcttg gttaaggatg aagatgagat
     1321 tagtataata gactgggaac aggctgtctt ttcaaatgat gaaaaagttg tacataaagt
     1381 tgcagcccct ggttttagag catggcgaga aacacttccc agtgagatag attggtatgg
     1441 tattagacaa atagctcatt atttatacat gccactagta actacatcgg atttgacata
     1501 caactatgta agtcaaacca ggatagaagg aaaaaaacta tttgagtctt tgggttatac
     1561 aagagaacat atagattatg tagaaagttt attgtcatat ctagattcta aatgtccaca
     1621 gattgagaat atttccagga aaaaagtttt aaaacccatg catgagatta gaactatcga
     1681 gagtgagcaa gatatacaag attttattat aaaattattg agagggttta cgctaactta
     1741 tggacagtgg cgtaaagaat ttcaatcaag attcttccca gttcattatt atggtctgaa
     1801 ttttaatcaa ggaattgcgt tttcagattt agctatcctt tggagttatc aacaactagc
     1861 taagaaagta aaaaatttca agtttgatga ctattatgag attcgaacac aggttattaa
     1921 tgaggcagta aataatttta agaaatcgtc cctttctggt ctttttgatg gtaaaattgg
     1981 tacaatctgg ctcatttatg aatttgggga gatagatcgg gcagttgaac tttttacaac
     2041 tcattttata gagatatttg agaattcaca aaataaaaat ttatatagtg ggcaggctgg
     2101 aattttactg gttggactgt attttcttag taaaggggaa attgataata aactaggaga
     2161 agaaatacta attaggctta gagaatatac tttaaattat atagaaaatc cagaaacttt
     2221 ttgtaaagtt ggcgctagtg atgttcagag taatgatcct tatgagaatt ttggtggatt
     2281 actatatggt cacgcagggg tagcttggct cttcggtgaa gcttataaat taactggtga
     2341 aagtatctat aaaaatggtc tagaattggc tgtagataaa gaattagttg cttataaagt
     2401 agatagtaat aattcattgc agtacagcca aggtcataga ttactaccat atctagcaac
     2461 tggaagtgct ggcctgcttt tacttattaa tagaaataaa gaaatcttgt caagcaaata
     2521 cttaaaatat ttaacttctt tagagagggc aactgatgta gttttttgtg tattaccagg
     2581 tttatttaac ggattttgtg gtcttgaagt tgctaataat atatatagtg atatcgatga
     2641 taacttttca ggacaaaaga aattaattga acaactttat agatatttgt gtgtaattga
     2701 agaaggattt gttattgcgg gagataatgg tttaaagata acaacagata ttgcttcggg
     2761 atttgcgggt gttgcaattg gattggtatc aataatggat aataaattga cgattcttcc
     2821 tcaaatataa tatttagata ccattattaa ggggtcatac ttgtgaatca gagtaatgaa
     2881 atatttttaa atacaataca ggaaaaaaca cactataaga ggtctatctc ttcatcattt
     2941 caggaattaa aaaaatggaa ttctttgata tttaggagag ggcgatattg gtaccaattt
     3001 gataattgga gtatacccaa tactggtgta ataaaggaat ggtatgtcga agataatgac
     3061 tggattccta aggttagttc ttccagttta gacaattcaa attcacttaa aattgtcttt
     3121 gatgtggaaa aatatacttt gccagatgat agtatcttac aggatgttag gatttcatct
     3181 gatgagagtt atatagtttt ggttgtatcc tcactgcgta gcactaattt aattggaata
     3241 aaaaaatata ctatggaaga gttatttatc attgaagata tttcagtaga aagttcgttc
     3301 tatttgggta aattcggtgt tatgtatact cgctccaaag agtacgggag gccaagtaag
     3361 ttattctata aatcttttga tagctttaca gaagaggaac tgtttgaaga aaacgaatgc
     3421 tcttttcgat taaaaatagt ccacattgat agcaataatt gttttgtaaa gtcagtagac
     3481 tttcagaaag gcaggatttt tctatacagt ttcgaccgga cgggttttgt tagacactct
     3541 tacacagaaa cggtagcccc aacacctaga gatatcgctc tatttagtac agaaaaagca
     3601 cagtactttc ttgggctctc ttcaactgaa gaaaagaaag atcaactaat tctaagggaa
     3661 acttcttcgg gagacagagt ttctattact ataccatatc aagatagggc tagaagagtt
     3721 cactgtatag gacgttatat ccttttagac tgttcaaacg cagcgaattc cgtcttttat
     3781 cttgctacat ttaaaaataa tagtttgagg gagttgagtg ttaataagat aacatttgat
     3841 gaaaagacaa cactttatga aaattcattt tctgatcgtg ttcttctgtt tttagagagg
     3901 agaacttttt acgaaaaaat acttagtttt gatttaatag aaaatacatt aaaaactgaa
     3961 tttgaaagac ccatcataaa atcgaataat actaaatatt tttctaaggt gatttggact
     4021 aaaaaagaca gttatgatgt aagcataccg atttctttat tttggaaaag tgaagatacg
     4081 gatgagctcc caagaagaaa aaaatgtatt ctaagtgtct atggggctta tggtaagaat
     4141 gataattctg atttagatga aattatgtta tctataatag atgcaggttt tatttatgct
     4201 atagttcatg taagaggtgg aggctatttg ggtggtgaat ggtatcgctc aggaaaggcg
     4261 ttaaacaaat ggaattctat cagagatttt attgagggag taaattattt aagggaaaat
     4321 gatgtaattg acagtaagcg attaggttta ataacttcta gtgcaggtgg aataattgct
     4381 ggtgcggtgt tgaacgagga aaaaaattta ttgcaaagca ttctcttatt ttcgccattt
     4441 ataaatcctt atgatacact tcagaatcca aatgatcctc tttctaagac cgaaatagca
     4501 gagtggggag atattagaga ccctgaagta aaggcttata taaagtcata ttcgcctatg
     4561 caaaatattg aaaaggcacg agactcaaat actgttatag ttaatatttt gggtgagaaa
     4621 gacccatata ttaataataa cgaagtgata gagtggtcaa agaaattaaa ttctattgga
     4681 gttaaaagtt tgttgtattt aaacaaagca gctggtcatg gaggttttac tccatcagat
     4741 gttctcttaa tgattgatac tttaaattat ttctttgaag aagtgggaag gaataactta
     4801 tgaattattt aaaatttata aaaaagacta aacttatatt aatggggatt ttaatatttc
     4861 tatcttcgtt taatggtgtc ttgctctcag gaattattgt atatgcaggt agtttaaatc
     4921 agacttcctc attttctgac gttctaagat ttggtgctat aagtattctg ggttggtcag
     4981 caatctatat atcaaattac tatttagaag taacggaagc atcaataacg aaagatataa
     5041 atgtaaaaat taaacaagga tattttagag aacagtatct ttcttctgaa atggttaaag
     5101 attactcatc tattatttca gttttgtcaa atgatttgag attaatcgaa gaaaactatt
     5161 ttagacaaat ttttgaaata atttcttcaa tattgttgtt catcgtctct ctaagtttta
     5221 tgctttattt aaacttccta gtttcaataa tatttattgt attatcagca ttgccgatta
     5281 tagtacctgt ctttatgaag aagatgttgt ctaattcagc taatgagtac tctaacagca
     5341 atgcagagta tactcacata ataaaagaaa tttttaatgg ttttaagaca ttaaaatctt
     5401 attctgttac taaagaaata attagtttgt cggataaaaa gttggataaa ctagaagatt
     5461 ctacttttaa tttgaaacga tcagaggttc tttcaaaatt ggttgcagta ctaatttcag
     5521 gtttttgctt tctagttccc ttggttgtag gatgttattt tgtaatttat cataaaagcc
     5581 tttcttttag tgaactgata ggtattttct tagcaaacga taaagtttta gggccgatac
     5641 aatcaattgc ctattcatta aataagataa atacaaccaa agatttaagg aaaccgtttt
     5701 taaaatactt aagtggagag aagaatttta tagacgctga acatgataat aacggactgt
     5761 atacttcatc aatagatgag atacacatga aagatgttgt atattctatt acaccagaaa
     5821 ataaattaag tattgacttc tcatttaagt caccatttag ggtattatta acaggaactt
     5881 ctggtagtgg gaaaacaacg attttaaatt taattaatgg ttctttaaag ccacaaaaag
     5941 gttatgtaaa tttgttatca catgggaaaa agagttcaga ttcaatacca acagttgatc
     6001 agacaccata tatttttgac actactattc gtgagaacgt aactttattt caaaatgaat
     6061 atttttcaga tgatcagata attgaggtgt taaaaaaggt aaatctatat gaagaattag
     6121 aaaagataga tatactaaat tatcaatgtg gtgaaaatgg tagtaatttg tctggaggtc
     6181 aaaaacaaaa aatagcttta gctagagctc tgattagaaa taataaagtg tacttatttg
     6241 acgaaatatc agctaattta gataatgata attcaaattc catacatgat attctgttca
     6301 atttaggtat ttcatttatt gaagtttcac atcattatga cttaaatgac aagagataca
     6361 ctgatatata taaattggaa aatggaacac ttttcaaaat taagtgattg gaggcaagaa
     6421 tatggataaa gattatatat taaaagtgaa agggctgtat catcaatttt tactaggaaa
     6481 taataaaacg ttgcaagtgc tgaaaaatgt ttctctttct gcttcgagag gagaatttat
     6541 aagtattcta ggaattagtg gttctggaaa gtcaacttta ttaaaatgta tttctagttt
     6601 gcttgaacca acaagtgggg aagtaatttt aaatggaatc aacccctata aaatcagaaa
     6661 tgcaaaattg tcaagtataa gacgtaacga agtatctttt atatttcaag catacaattt
     6721 aataccttcc ctgccggtaa tagaaaatat agcacttcct ttgcgattat cacaaaaaaa
     6781 attaactatt aaaaatgtag aaaacttact caaaagaatg aagtttaatg ctggcttaaa
     6841 cgattttgtt ggaactctgt ctggtggaga acaacagaag gttgctatag ctagagcggt
     6901 tattgctgat agtgatataa tatttgctga tgagccaact ggggctttag acagcgtttc
     6961 tcgtgaagta atttttgaat tattgagaga gttagtaggg gcgggtaagt gtgtaattat
     7021 ggtaacgcac gatatagaat tggcctcgaa aactgatcgt gcattaatat tgaaagatgg
     7081 aaaaattttc aaagaacttc atagacctag cggggaagag ttgtataaaa tcttagaggt
     7141 acaatcaact acggaggaat agagatgctc agattagttt actatcaatt tttacataat
     7201 aagaaacaat ggttaggcgt ttcaccagta atttttgttt cgagtttagt tatgggattg
     7261 gctgttaatg gggtaattaa tgttgagaat aattcgcaag tatttgtcgg acttccagat
     7321 cctaaaccaa tttttatgtt tccgatagta ttcggaggag taacattatt ctttgtgctc
     7381 tctaacataa taaatatgtt ggttgaaatt tttagagatg attacgaact tctggaggtg
     7441 ttgggagcaa gtctccttca actatcattt cttgtggggg gacagatttt tatcatttcc
     7501 tcgattatta gttttattgc atatctatgc tctatatttg ttacgtcaaa ttattattat
     7561 tttttacaat actttttcgg ggaaaatata ttacctgata tccaatttca aacgagtgct
     7621 gttggatgta tcattacagt agtgttgatt tcatttttag cctttctaag tggttgcttt
     7681 tatacgttca agaagattag aaataggaag agttctaaaa taaggcatgt tctttcaata
     7741 gtaaaaagaa tactgctatt ggctggtttt agtgttatct ggttgctttc tttgcaacaa
     7801 attttccaag atagcacaat tttagcgaag gcccagataa tattcaatat tgtaatctta
     7861 gatattgtga ttatttatca attatctcct tttatacagt catgttttat caaactactt
     7921 tctataatta tatttagaaa taattttatg ttcattgctt cgaagtggaa tttactatat
     7981 cgtaagcctt atataaaatc tatcagtgct gcaattacag gagctatatt actaatttct
     8041 agttttcaaa tgatttctca gaatatacta tctcaatttc aagatgacag tgatttagag
     8101 ctaaaagtgg catttattgt ctatgtagga gcaccaattt tgatagtact tgcaaatatt
     8161 atttcaattg catttttgtc atcgcatcaa gaaaggattg agattcagca atttgaaatt
     8221 ttaggaactt ctaattacca gatggttaag attaaagttg gtgaggctat atttttgaca
     8281 tttgttactt cattaattgc atttttactt aacattaaaa ttatggcttt aatatactac
     8341 tctttagagg atgttttaat agatgatatg aatcttttgg ggttaatact tccaaatttt
     8401 atagtgtcta ttattttatt tattttaata tttattacta aaagttccta ttttatcttt
     8461 aagaatgcaa aaattatttc ttaaaaattt gtaagttttc gctatataaa atagttaaat
     8521 ctattttgta tcattgcttg cattttactg gtggagaga
//
LOCUS       DAVAZT010000074         8550 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVAZT010000074 DAVAZT010000000
VERSION     DAVAZT010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8550
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.074"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..128
                     /locus_tag="VQT45_001925"
     CDS             <1..128
                     /locus_tag="VQT45_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET2360191.1"
                     /translation="FQSLNQLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
     gene            complement(257..460)
                     /locus_tag="VQT45_001926"
     CDS             complement(257..460)
                     /locus_tag="VQT45_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2360192.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(453..1535)
                     /locus_tag="VQT45_001927"
     CDS             complement(453..1535)
                     /locus_tag="VQT45_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET2360193.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(1661..2443)
                     /locus_tag="VQT45_001928"
     CDS             complement(1661..2443)
                     /locus_tag="VQT45_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HET2360194.1"
                     /translation="MVYTSLSSKDSNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2443..3786)
                     /locus_tag="VQT45_001929"
     CDS             complement(2443..3786)
                     /locus_tag="VQT45_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HET2360195.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQSL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(3885..5201)
                     /locus_tag="VQT45_001930"
     CDS             complement(3885..5201)
                     /locus_tag="VQT45_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HET2360196.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQSLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5394..6615
                     /locus_tag="VQT45_001931"
                     /pseudo
     CDS             5394..6615
                     /locus_tag="VQT45_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
     gene            6814..8388
                     /locus_tag="VQT45_001932"
     CDS             6814..8388
                     /locus_tag="VQT45_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2360197.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
BASE COUNT         2454 a         1652 c         1892 g         2552 t
ORIGIN      
        1 cgtttcagtc gcttaatcaa ttggaacaag ctattgtaga ctatattgat tactacaaca
       61 ataaacgaat taaggtaaaa ctaaaaggac ttagtcctgt gcaatacaga actaaatcct
      121 tcggataaat taattgtcta actgtttggg ggcagtacat attcaacacc tgatactatg
      181 cgttttattg tgggaagatt ttcctcattt tctagtgaaa ttgaactttt tctaacatct
      241 tttgatagat gacttcttaa tcaattatca tttccattgt tgtttcttgg ggtttcatcc
      301 cttgtctttg ataaaagcgg agagcaccct cgttatcatt ccagacactt agggttagat
      361 tattgcagcc aatttcttta gcataatagc agaaaaatga caataaaata gcccctagat
      421 attttgaaag gaaagcatag gggctatata gtttaatcaa aataaagcaa atctttgctg
      481 gtgcttgtaa agaggtcgaa gccatccttg gtaacaacac cgcagtcttc aatacgaaca
      541 ccgactttac cagggatata gatacctggt tcaacagaga agcacatgcc ttcttcgatg
      601 accatgtcgt ttccttccat gatagatggg aattcatgga catccatacc gataccatgc
      661 ccgagacggt ggttgaagta ctcaccataa ccagcttttt cgatgacctc acgggcagcg
      721 cggtccactt catgagcagt cacacctggc ttgataaagt caagagcagc ttgttgggct
      781 tcaagagtca agttgtaaat atctttcttg aattggtctg gtttgccgac agcgactgta
      841 cgagtcatat ctgacgcata gccattgacc agaacaccca ggtcaaagag gagaagagca
      901 tcattttcaa ccttattagc tgctggaatg ccgtgtggat tcgcagcatt atcaccagtc
      961 aagaccatgg tatcaaagct catttcataa ccttcacgtt tcatggcaaa gtcgatttgt
     1021 gcgatgatat ctgtctcagt cttatcaaga gaaatattgt caaaaccaac atgaacagcc
     1081 ttgtcagcat aaagacctgc aaccatcatt ttttgcactt catcagctga tttgatgagg
     1141 cgcatgcgtt ggatacgagg agtgaggttg tcaaactcag cagtctcaaa aactgttttc
     1201 aaaccatggt atttggtcaa gatgagattg tcaaactcaa cagcgacacg tttgaagtca
     1261 agttgtggaa gagcatgttt gattttttgc catggatttt cagaatcgac atagcccact
     1321 actgggaagg aaacggtgct acttgcacgt tctacttcaa gagctgggac aaagaggaga
     1381 ggttcctgat ccgctaggac aaagaggaac atttggcgtt catggggatc actgtaaaaa
     1441 ccagtgaggt aattgattgt gacggggtca gatacgacag cgacgtctag tttttctgat
     1501 tcaagatatg ttaggatttg ttgtaattta gacatatgct accttctttc tacccctcta
     1561 ttttggcaaa aaatgagaga aaatgcaagg gagaagggta aaagaaaaga caaaaaactc
     1621 cgacaagata acggagttct ttgatatcat tttcctttgt ttaagaaaag tcagccttgc
     1681 ttttgacgtc actgtactct tcagcgattt cttggctgag aatgtcctca taggcaggga
     1741 gttggatgtc ctgaccatat ttcttcttga gggcagtagt aactaggcga taagccagat
     1801 tggcattacg agagaggata ggcccgtgga agtaggaacc aaagacattc ttataatgaa
     1861 ccccttcacc gaccttttct tcgttgtttc catttccata gacaacctgt cccagcggtt
     1921 tttggtcatc agagaggaag gtacgacctt ggtgattttc aaatccatag taggtttcat
     1981 cgaaatcttc attgtgaatc ttgatgtcac cgataaaacg gttattggtc tggttgagcg
     2041 tgtagtgtcc catgacccct agcccttcga tacgttttcc tgaagcttca acataatatt
     2101 gacccaatag ttggaaacca ccgcagatag ccagaactac accgtcgttt tggatgtagt
     2161 tgtcaatgct ctctttttta gcaggtaggt cgtctgcaat gatactttgt tcaaagtctt
     2221 gaccaccacc gaaaaaggcg atgtcgtagt gattttcatc aaagtcatca tggagagaaa
     2281 cgatgtcaac ggtcacatgg gctcccagtt tttcagccac atacttgagc atgaggatgt
     2341 ttccattgtc cccgtaggta ttcatgagat ttccgtagag gtgggcaatg ttgagctgat
     2401 aggggtaatt gctatctttt gaggaaagtg aagtataaac cattagttca tctcctttct
     2461 aacaatctga cgactagcca gcagttcacg aaattccagc atggcagtat aagttgccag
     2521 aatataggca tgcttgcagt cttgattctc aatggtcttg agaacttgct ccagattact
     2581 cgtttcagtg attttctcag ctggatagcc agtcactcgg aggcgacgag cgatttcaga
     2641 atgacgaaca ccgccagcgt tgatttcagg aatgtccatg tcagtgattt gctcaaagtc
     2701 tgcatcccag atccagctag tgtcaattcc atctgcatag ttggcattaa ggaggacaga
     2761 taggctaaat ggataaggtg ctagtttgat catttcgata gcttgggttg caccgactgg
     2821 atttttaatc aagacaaggg tacattcctt gtcaccgata tgaaaggttt cttggcgtcc
     2881 aaagacagca cggctcttgt caaatccctg tttgatgagt tgggaatctg cgccgaggaa
     2941 acgggcgatg gccacagcag ctagggcgtt atagatatta tagagcccgc cgatttggat
     3001 accgtattct tggccgtcta tgacaaagcg agagcgattg ttggtcaact caaccagttt
     3061 tgtcaaacga tagtcgagat caggacgttt acatccacaa ccttcacaga tataggcacc
     3121 caagtttgca taggtattat gctcatattt gaggatgcct tggcagtcag gacagagaat
     3181 cccttcggta ttgtagtgag ccagttgggc tggtcctttt tccaagtcaa aaccaaaata
     3241 ctctataggg tttggaatag ttggcttgta gaaaagtgga ctgtctccgt taaggagaac
     3301 agtagcagtt ggaacttttc gaatggcatc caatatcatg ttataggtag tatagatttc
     3361 accgaaacgg tccatctggt cacggaagat attagtaatg acaaaaagac taggctggat
     3421 atagtcacag atacgagata gactggcttc gtcaatttcg aggacggcaa tatttttccc
     3481 agtttttgaa gatttggctg ttaggaaggt tgttgcaatc cctgtaatca tgttggcacc
     3541 gcttgggttg gttagaactt gaccataaac ctcttttaaa atgccgacag tgagggcagt
     3601 tgtcagggtt tttccatttg ttccagtgac aacgacaatc tcgtagttct tagctaggct
     3661 ttgtaaaata tctttatcaa attgaagggc gactttccct gggagcgtac ttccacgtcc
     3721 aagacggctt aaaacgaagt gggaagaacg cccagcaaga aggcccaaag tagtttttaa
     3781 gttcatgttt ctattatatc acaaaagagg gaaaagacag atttggtgtt tcgtagaagt
     3841 aaaaacagcc caaagagggc tgtcagttaa gatgagattt caacttaaat cgcaaacaag
     3901 tcattcaagt tctcagccaa ggttgggtga gtgaagattt gttttgtgaa gtaagtgtaa
     3961 ggaatcttgt tgtccatagc aacagtaatg atgttgatga tttcttgaga accttctgag
     4021 aagatgcttg caccaagaat ttcttttgtt tcagtattaa caacagcttt gaaagctccg
     4081 cgaaggtctc catttacgtg accacgaggc atggctgcaa cagggatttc tttcactgcg
     4141 tatggaagtt tcaaatcagc tgcttggctt tcagtcaaac caacttgtga aagtgcaggt
     4201 gtgatgaaca tagtatttgg cacattgaga cggtcctcaa gtgtgtagct gccatctcca
     4261 gcaaggtagc tgtaaacaac acggaagtca tcaagtgaaa tgtaagtaaa ttgaaggcca
     4321 ccgttgacat ctccaactgc aaagacacca ggaacgtttg tttgacagtg tttgtctact
     4381 ttaatagcac cacgttcagt tagttcaata tctgtatttt caagttgaag tggttctaca
     4441 tttggtttgc gtccagttgc gtagagaagg gcgtcgaaac ggtaagtttc gtcttcagtt
     4501 acgacaagca cttggtcacc atcgtttttg atttcagtag tatggatatt ttgaagcaat
     4561 tcaatgccat cttcttccat gtattgttta gcaagagctg cgatggaagg ttctgcacga
     4621 ggtaggaatg tatccaaggc atctaggact gtgaccttgc ttccaagttt gttgtaaagg
     4681 ccggcaaatt caagaccgat atttccgcca ccaaggattc caagtttttc aggtaatttg
     4741 tccaagcttt ggatacctgt tgagtcaaag atgtttttgc ttgtagcaag tccaggaatt
     4801 ggcaagacgt ttgaaacagc accagtgttg atgacgattg tttcagcagt cagttctttc
     4861 ttttcatcac cagcttggat ttcgatgact ttatttgaaa ggaagtgagc ttccgcatca
     4921 aagatatcta cgcctgtacc agcaacagtc gcatagtttt taccgttgag gcgaccagtg
     4981 atcgtgtttt tagtagcaat cacttcttca aaagacaagt ccttttcagc agcaactagc
     5041 aaggttttag ttgggataca accaatgttg atacaagttc caccgtacat agccttgctg
     5101 cgttcaacga gggcaacttt tttgccagct gaagccaatt tacctgctag tgttttacca
     5161 gctttaccaa atccaataac aattaaatcg tatgttaaca tttatcttcc tcctattcga
     5221 atttcattct agcacaagaa aaaaactttt gcacaattct gctacggaaa agacagaaaa
     5281 agataaaaac gctttccaga caaaaaacta gtaatttttt gacaagcttg ataaactaaa
     5341 atcctatcta tttttatata agaaagaata aatgttcgaa aataggaggt tttatgaaat
     5401 cgaatcgtta tattattgcc tttgctgggg tcattttaca cttaatgctg ggttcgactt
     5461 atgcttggag tgtttatcgt aaccctatta ttgaaaaaac gggatgggat caggcttctg
     5521 ttgccttcgc ctttagtcta gcaatctttt gtttgggctt atcggctgca tttatggggc
     5581 gtttggtaga aaaatttggt ccgaaagtca tggggagtct atctgctttt ctatacgcag
     5641 gtggaaatat cttaacagga tttgcaatag accgtcagga actgtggttg ttgtatctag
     5701 cttatggcat tttaggtggg cttggtttgg gagcaggcta tattacccct gtgtcaacga
     5761 ttataaaatg gtttcctgat aaacgtggtc tcgcaacagg tttagcgatt atggggtttg
     5821 gttttgcttc tttattgact agtcccatag cgcaacacct catcgcaggg gtagggattg
     5881 tagaaacttt ttatatttta ggagcaagtt actttattat catgctccta gcttcacaat
     5941 tcattaagcg tccaaatgag caagagcttg caattttatc ttcttcaggg aaagaaaaaa
     6001 cagcctcttt gacgcaagga atggctgcaa atcaggctct aaaaagcaat cggttttata
     6061 tgctttggat tattttcttt atcaacatag cttgtggttt aggcttaatt tcagcggcat
     6121 cgccaatggc acaggagatg gctggcttgt ctacaagtca tgcagcagta atggtgggtg
     6181 ttttggggat tttcaatgga tttggtcgct tgctctgggc gagtttgtct gactatatcg
     6241 gtcgccctct aacctttagt atattactgc ttgtcaatct tttctctctc actttggctc
     6301 tttacagatt ccgttttatt tgtagttgct atgtctattt tgatgacttg ctatggagct
     6361 ggtttttctt tgattccagc ttatctcagt gatatttttg gaaccaagga attggccgct
     6421 ctgcatggtt atattttaac agcttgggca atggctggtt tagcgggacc tattttatta
     6481 gcagagactt ataaaatggc tcattcgtac acacaaacct tgttcgtttt tctcatttta
     6541 tacagtatcg ccttggcttt gtcttattat ctaggtcgtt caatcaaaaa agaaagtcaa
     6601 aaaccgctta catgattttc tgtagaaatg gggctatctt ttgctctggt cttgtgttat
     6661 actagatagg ttgcaaagaa aacagtactt ttcttttgtg gaaaagaagc aacacgattt
     6721 tatatctagt tatatgaaaa tacgtcataa aaagaaaagt ataaactaag ccctataggg
     6781 tggcttcgca ccacctttag aaagaagaat aacgtgaaat ttaatgaatt aaacttgtct
     6841 gctgatttgc tagcagaaat tgaaaaagct ggttttgtag aagctagtcc tatccaagaa
     6901 caaactattc ctttggccct tgaaggcaag gatgttatcg gtcaagctca gactggtaca
     6961 ggaaaaactg cagcctttgg cttgcctacc cttgaaaaaa tccgtacaga agaagcgact
     7021 atccaagctt tggtcatcgc tccaactcgt gaactagctg tccaaagtca agaagaactc
     7081 ttccgctttg gtcgtagtaa gggagtcaaa gtccgttcag tatatggcgg atcaagcatt
     7141 gaaaaacaaa ttaaggctct taaatctggt gcccatatcg tggtgggaac tccaggtcgc
     7201 ctcttggact tgattaaacg caaggccttg aaattacaag acattgaaac ccttatcctt
     7261 gacgaagcgg atgaaatgct taacatgggc ttccttgaag acatcgaagc cattatttcc
     7321 cgtgtacctg agaaccgtca aactttgctt ttctcagcaa ctatgccaga tgccatcaaa
     7381 cgtatcggtg ttcagtttat gaaagcccct gaacatgtca agattgcggc taaggaattg
     7441 acaacagaat tggttgacca gtactatatc cgtgttaagg aacaagaaaa atttgacacc
     7501 atgactcgtc tcatggatgt ggcacaacca gaactcgcta ttgtatttgg tcgtaccaaa
     7561 cgccgtgtgg atgaattgac tcgtggtttg aaaattcgtg gcttccgtgc agaaggaatt
     7621 catggcgacc tagaccaaaa caaacgtctt cgtgtccttc gtgactttaa aaatggcaat
     7681 cttgatgttt tggttgcgac agacgttgca gcgcgtggtt tggatatttc aggtgtgacc
     7741 catgtctaca actacgatat tccacaagat cctgagagtt atgttcaccg tatcggtcgt
     7801 acaggtcgtg ctggtaagtc aggtcaatct attacttttg ttgctccaaa cgaaatgggt
     7861 taccttcaaa tcattgaaaa cttgactaag aaacgcatga aaggtctcaa acctgcaagt
     7921 gtagaagaat ccttccaatc aaaaaaacag gtagctctca agaaaatcga acgtgatttt
     7981 gcagatgaaa ccattcgtgc caactttgag aaatttggta aggatgctcg caaattggct
     8041 gctgagttta ctccagaaga attggcaatg tatatcttga gtctgacagt ccaagaccca
     8101 gatagccttc cagaagtgga gattgcacgt gaaaaaccac taccgtttaa accatcaggt
     8161 aatggtttcg gtggtaaagc taagggaggt cgtggaggcc gtcgtgggga cgaccgtcga
     8221 gagcgtgatc gccgtggcaa tggtcgccgt gatgagttca aaaaaggaag tcgtggcaac
     8281 gatcgttttg ataaggaaaa acgttaccgt aaggataata aaaaaccacg caatacttta
     8341 agcgaaaagc aaacaggctt tgttattcgt aacaaaggcg ataaataaga aaaagcggtt
     8401 caaaatgaat cgctttttta tataaggaga ccgaatgtga aaagacaaat aaaattacta
     8461 tattatcttt tataatgtta tgatacacaa aaataggcaa cttgtcaata gaaaaggaac
     8521 aatttaatta aaaatattct ggtttttaat
//
LOCUS       DAVAZT010000075         8107 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVAZT010000075 DAVAZT010000000
VERSION     DAVAZT010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8107
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.075"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            120..497
                     /locus_tag="VQT45_001933"
     CDS             120..497
                     /locus_tag="VQT45_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET2360198.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIALV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            732..2123
                     /locus_tag="VQT45_001934"
     CDS             732..2123
                     /locus_tag="VQT45_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HET2360199.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIDQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            2237..3079
                     /locus_tag="VQT45_001935"
     CDS             2237..3079
                     /locus_tag="VQT45_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HET2360200.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQEQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            3352..4113
                     /locus_tag="VQT45_001936"
     CDS             3352..4113
                     /locus_tag="VQT45_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET2360201.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            4483..5400
                     /gene="glyQ"
                     /locus_tag="VQT45_001937"
     CDS             4483..5400
                     /gene="glyQ"
                     /locus_tag="VQT45_001937"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HET2360202.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
     gene            5660..7696
                     /locus_tag="VQT45_001938"
     CDS             5660..7696
                     /locus_tag="VQT45_001938"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HET2360203.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSELFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            7738..7995
                     /locus_tag="VQT45_001939"
     CDS             7738..7995
                     /locus_tag="VQT45_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HET2360204.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
BASE COUNT         2554 a         1431 c         1794 g         2328 t
ORIGIN      
        1 gctttctttt ccgaataaat agatagaagc atagaatcta gcaaacctag atttaaaaat
       61 gtgctataat agaaggagga aaaggaggat tctcagacat ccaggtatca gcccaactaa
      121 tgatttgtca atttatccgc gatatgctgg acttgccagc aaaaaatgtg acgattttgg
      181 agggaagtaa cattcacgtc ttgccttcca tgccctactc agcgcaagat ttctatacta
      241 gtatagacgt cttggcggag ttagataatg gaatccaagt tatcatcgaa attcaggttc
      301 atcatcagaa ttttttcatc aatcgcctat gggcttatct gtgcagtcag gttaatcaaa
      361 acctagaaaa aattcgccaa cgtgaaggtg atacccacca gagctacaaa caaatcgcac
      421 tagtatacgc tatcgcaatt gtcgatagta attacttctc agatgaccta gcttttcata
      481 gttttatagt aaaatgaaat gagaacagga caaatcgatc aggacagtca aatcgatttc
      541 taacaatgtt ttagaagtat aggtctacta ttctagcttc aatctactag aaattccata
      601 gatagaaaac tacataatct ctacagatac ggatgttgga gttgatgtaa gatgctttgg
      661 cttgctagag gaattgtgga ttgccaaatt gtatcattga aattattgct caaatttgtt
      721 atgatataaa tatgaataaa agtagactag gacgtggcag acacgggaaa acgagacatg
      781 tattattggc tttgattggt attttagcaa tttctatttg cctattaggc ggatttattg
      841 cttttaagat ctaccagcaa aaaagttttg agcaaaagat tgaatcgctc aaaaaagaga
      901 aagatgatca attgagtgag ggaaatcaga aggagcattt tcgtcagggg caagccgaag
      961 tgattgccta ttatcctctc caaggggaga aagtgatttc ctctgttagg gagctgataa
     1021 atcaagatgt taaggacaag ctagaaagta aggacaatct tgttttctac tatacagagc
     1081 aagaagagtc aggtttaaag ggagtcgtta atcgtaatgt gaccaaacaa atctatgatt
     1141 tagttgcttt taagattgaa gagactgaaa agaccagtct aggaaaggtt cacttaacag
     1201 aagatgggca accttttaca cttgaccaac tgttttcaga tgctagtaag gctaaggaac
     1261 agctgataaa agagttgacc tccttcatag aggataaaaa aatagatcaa gaccagagtg
     1321 agcagattgt aaaaaacttc tctgaccaag acttgtctgc atggaatttt gattacaagg
     1381 atagtcagat tatcctttat ccaagtcctg tggttgaaaa tttagaagag atagccttgc
     1441 cagtatctgc tttctttgat gttatccaat cttcgtactt actcgaaaaa gatgcggcct
     1501 tgtaccaatc ttactttgat aagaaacatc aaaaagttgt cgctctaacc tttgatgatg
     1561 gtccaaatcc agcaacgacc ccgcaggtat tagagaccct agctaaatat gatattaaag
     1621 cgactttctt tgtgcttggg aaaaatgttt ctgggaatga ggacttggtg aagaggataa
     1681 aatctgaagg tcatgttgtt ggaaaccata gttggagcca tccgattctc tcgcaactct
     1741 ctcttgatga agctaaaaag cagattactg atactgagga tgtgctaact aaagtgctgg
     1801 gttctagttc taaactcatg cgtccacctt atggtgctat tacagatgat attcgcaata
     1861 gcttggattt gagctttatc atgtgggatg tggatagtct ggactggaag agtaaaaatg
     1921 aagcatctat tttgacagaa attcagcatc aagtagctaa cggctctatc gttttgatgc
     1981 atgatattca cagtccgaca gtcaatgcct tgccaagggt cattgagtat ttgaaaaatc
     2041 aaggttatac ctttgtgacc ataccagaga tgctcaatac tcgcctaaaa gctcatgagc
     2101 tgtactatag tcgtgatgaa taagcaagaa aaaataggtc tgttagatat ttgacagact
     2161 tattttttac agaatatagt actacttaaa aaatgtttta tgctataatt gatgaataaa
     2221 atagaaggag aagcatatga atacctatca attaaataat ggagtagaaa ttccagtatt
     2281 gggatttgga acttttaagg ctaaggatgg agaagaagcc tatcgtgcag tgttagaagc
     2341 cttgaaggct ggttatcgtc atattgatac ggcggcgatt tatcagaatg aagaaagtgt
     2401 tggtcaagca atcaaagata gcggagttcc acgtgaagaa atgttcgtaa ctaccaagct
     2461 ttggaatagt cagcaaacct atgagcaaac tcgtcaagct ttggaaaaat ctatagaaaa
     2521 actgggcttg gattatttgg atttgtattt gattcattgg ccgaacccaa aaccgctcag
     2581 agaaaatgac gcatggaaaa ctcgcaatgc ggaagtttgg agagcgatgg aagacctcta
     2641 tcaagaaggg aaaatccgtg ctatcggcgt tagcaatttt cttccccatc atttggatgc
     2701 cttgcttgaa actgcaacta tcgttcctgc ggtcaatcaa gttcgcttgg cgccaggtgt
     2761 gtatcaagaa caagtcgtag cttactgtcg tgaaaaggga attttattgg aagcttgggg
     2821 gccttttggt cagggagaac tatttgatag caagcaagtg caagaaatcg cagcaaatca
     2881 cggaaaatcg attgctcaga tagccttggc ctggagcttg gcagaaggat ttttaccact
     2941 tccaaaatct gtcacaacct ctcgtattca agctaatctt gattgctttg gaattgaact
     3001 gagtcatgag gagagagaaa ccttaaaaac gattgctgtt caatcgggtg ctccacgagt
     3061 tgatgatgtg gatttctaga aaatcataaa aagaattgta cattattcta atttttgata
     3121 taatagtcag caggaaagaa agtcttatgg cgttcttcaa gcgagcttgg gatagtggga
     3181 gccaagtagg gcaaaataat gagctggcgc tttctgtagt attttcaaaa acaatgaagt
     3241 aataaattag ggtggaaccg cgtttctgac gcccctaggt taaatcaacc taggattgtc
     3301 ggacgcggtt cttttgctta ttcagtctat tgtgtgaaag aaaggagagc cgtggacaac
     3361 ctttatcttg taaaagacga tagtcaacta gctacatttc gtgattttgt agtaagaaat
     3421 actgaaaagt tgaaagatta tcaatctttt ttaaagaatg aacttgcagt ctgtgattta
     3481 ccgcaagccg ttatttggtc agattttaat gctgctacac agattattag ggaaagcgct
     3541 gttccagcct atacaaataa tagacgaatg gttatggcgc ctgatttagc tgtttggaaa
     3601 gagttgtatt tgtatcaatt gatggactac gagtgttctc agcaaactca agcaatagaa
     3661 agtcactatc attctttatc tgaaaatttc ctcttacaga ttgtaggaca tgagttagct
     3721 cattggtcgg agcatttttt agatgatttt gatggttatg actcttatat ctggttcgaa
     3781 gaggggatgg ttgaatatat tagtcgcaag tatttcttga cagaagagga atttcaagcg
     3841 gaaaaaattt gtaatcaatc tctcgtagaa ctttttcaga agaagtatgg ttggcattca
     3901 ttgaatgatt ttggttcttc gacttatgat aagaactatg caagtatttt ttatgaatac
     3961 tggcgcagct ttttgacagt agataagttg gtagaaaatt taggtagtgt acaagcggtc
     4021 ttagattctt atcatttatg ggcaaataca gaaaaaactt ttcccttgtt agattggttt
     4081 gttcagcaga aattaattga aaaagaaata taaaaactaa aggagtaaac aatgtctaag
     4141 aaattgacat ttcactgcgt cagtggcaga aacctcctta cagtcggact gccccacgct
     4201 cagcactaga gtgcctgagc tagacgcagt actaactcgt cttgcctcgt atgatcgacg
     4261 aggcagactc atgtcgcaag taattatttt ttattaagga gtaaacaatg tctaagaaat
     4321 taacatttca ctgcatcagt ggcagaaacc tccttacagt cggactgccc cacgctcagc
     4381 accctagtgc tgagctagac gcagtactaa ctcgtcttgc ctcgtataat cgacgaggca
     4441 gactcgtgtc gcaagaaatc attttttatt aaggagtaaa caatgtctaa gaaattaaca
     4501 tttcaagaaa ttattttgac tttgcaacaa ttttggaatg accaaggttg tatgcttatg
     4561 caggcttatg acaatgaaaa aggtgcgggg acaatgagtc cttacacttt ccttcgtgct
     4621 atcggacctg agccatggaa tgcagcttat gtagagccat cacgtcgtcc tgctgacggt
     4681 cgttatgggg aaaaccctaa ccgtctctac caacaccacc aattccaggt ggtcatgaag
     4741 ccttctccat caaatatcca agaactttac cttgagtctt tggaaaaatt gggaatcaat
     4801 cctttggagc acgatattcg ttttgttgag gacaactggg aaaacccatc aactggttca
     4861 gctggtcttg gttgggaagt ttggcttgac ggaatggaaa tcactcagtt cacttatttc
     4921 caacaagtcg gtggattggc aactggccct gtgactgcgg aagttaccta tggtttggag
     4981 cgcttggctt cttacattca agaagtagac tctgtctatg atatcgagtg ggctgatggt
     5041 gtaaaatacg gagaaatctt tatccagcct gagtatgagc actcaaaata ttcatttgaa
     5101 atttcggacc aagaaatgtt gcttgaaaac tttgataagt ttgaaaaaga agctggtcgt
     5161 gcattagaag aaggcttggt acaccctgcc tatgactatg ttctcaaatg ttcacatacc
     5221 tttaatctgc ttgacgcgcg tggtgccgta tctgtaacag agcgtgcagg ctatatcgct
     5281 cgtatccgta acttggcccg tgttgtagcc aaaacctttg ttgcagaacg caaacgccta
     5341 ggttacccac ttttggatga agaaacacga gttaaacttt tagcagaaga cgcagaatag
     5401 tgagtaatac tgtactctaa aatcgttaga ggcaagtcga agacttgcta gagggatatg
     5461 caccgccgta ctgttatgtg gggatttttg aaaccttagg ttcaaaaatc agtcagctaa
     5521 atccactttg atgagattgt tggaaatctt gataaattta gcattggatt tccatacaga
     5581 ctcacagagt tagttagcga cgtccccagt acctaaggtg catatcaaaa aagattgaag
     5641 aaaatgtaaa ggaaaaaaca tgacaaaaaa cttattagta gaactcggtc ttgaagaatt
     5701 accagcctat gttgtcacac caagtgaaaa acaactaggc gaaaaaatgg cagccttcct
     5761 caaggaaaac cgcctgtctt ttgaagccat tcaaaccttc tcaacaccac gtcgtttggc
     5821 tgttcgtgtg actggtttat cagacaaaca gtctgatttg acagaagatt tcaagggacc
     5881 agcaaagaaa attgccttgg atagtgatgg aaactttacc aaagcagctc aaggatttgt
     5941 ccgtggaaaa ggcttgactg ttgaagatat cgaattccgt gaaatcaagg gtgaagaata
     6001 tgtctatgtc actaaggaag aagttggtca agcagttgaa gccattgttc ctggtgttgt
     6061 agatgtcttg aagtcattga ctttccctgt cagcatgcac tgggctggaa atagctttga
     6121 atacattcgt cctgtccaca ctttaactgt tctcttggat gagcaagagt ttgacttgga
     6181 tttccttgat atcaagggaa gtcgtgtgag ccgtggccat cgtttcttgg ggaaagaaac
     6241 caaaattcag tcagcattga gctatgaaga agaccttcgt aagcagtttg taatcgcaga
     6301 tccatgtgaa cgtgagcaaa tgattgttga ccaaatcaag gaaattgagg caaaacatgg
     6361 tgtacgtatc gaaattgatg cggatttgct gaatgaagtc ttgaatttgg ttgaataccc
     6421 aactgccttc atgggaagtt ttgatgctaa ataccttgaa gttccagaag aagtcttggt
     6481 gacttctatg aaggaacacc agcgttactt tgttgttcgt gatcaagatg gaaaactctt
     6541 gccaaacttc atttctgttc gtaacggaaa cgcagagcgt ttgaaaaatg tcattaaagg
     6601 aaatgaaaaa gtcttggtag cccgcttgga agacggagaa ttcttctggc gtgaagacca
     6661 aaaattggtg atttcagatc ttgttgaaaa attaaacaat gtcaccttcc atgagaagat
     6721 tggttccctt cgtgaacaca tgattcgtac gggtcaaatc actgtacttt tggcagaaaa
     6781 agctggtttg tcagtggatg aaacagttga ccttgctcgt gcagcagcca tttacaagtt
     6841 tgacttattg acaggtatgg ttggtgaatt tgacgaactc caaggaatta tgggtgaaaa
     6901 atacaccctt cttgctggtg aaactccagc ggtggcagct gctattcgtg aacactacat
     6961 gcctacatca gctgaaggag aacttccaga gagcaaggtc ggcgcagttc tagccattgc
     7021 agacaaattg gatacgattt tgagtttctt ctcagtagga ttgattccat caggttctaa
     7081 tgacccttat gcccttcgtc gtgcaactca aggtgtggtt cgtatcttgg atgcctttgg
     7141 ttggcacatt gctatggatg agctgattga tagcctttat gcattgaaat ttgacagttt
     7201 gacttatgaa aataaagcag aggttatgga ctttatcaag gctcgtgttg ataagatgat
     7261 gggctctact ccaaaagata tcaaggaagc agttcttgca ggttcaaact ttgttgtggc
     7321 agatatgttg gaagcagcaa gtgctctcgt agaagtaagc aaggaagaag attttaaacc
     7381 atctgttgaa tcactttctc gtgcctttaa cctggctgag aaggcagaag gggttgctac
     7441 agttgattca gaactatttg agaatgacca agaaaaagct ttggcagaag cagtagaaac
     7501 actcgtttta tcaggacctg caagtcagca attgaaacaa ctctttgcgc ttagcccagt
     7561 cattgatgct ttctttgaaa atactatggt aatggctgaa gatcaggctg tccgtcaaaa
     7621 tcgtttggca atcttgtcac aactaaccaa gaaagcagct aagtttgctt gttttaacca
     7681 aattaacact aaataaaatt tgataaacgg actttatctt attacaaagg agaagaaatg
     7741 gatccgaaaa aaattgctcg tatcaatgag cttgctaaaa agaaaaaaac agaaggctta
     7801 acaccagaag aaaaagtgga acaagccaaa ctacgtgagg agtacatcga aggttatcgc
     7861 cgcgctgttc gtcaccacat tgaaggaatc aaaattgtgg acgaagaagg aaacgatgtt
     7921 acaccagaaa aactacgcca agtacaacgt gaaaaaggat tacatggccg tagtcttgat
     7981 gacccaaatt cataatatgt actctttctt ttaacaaaga tagatgaaac gataacaaag
     8041 agactagcag tttgtgtttg ctagtctttt ttcgctaaaa aaggaaccat aatggttcct
     8101 aaaaact
//
LOCUS       DAVAZT010000076         7926 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVAZT010000076 DAVAZT010000000
VERSION     DAVAZT010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7926
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.076"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            226..6657
                     /locus_tag="VQT45_001940"
     CDS             226..6657
                     /locus_tag="VQT45_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HET2360205.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALNISDKEKV
                     VVDKETENKEKHEDIHNAIETSQDFKEKKTAVIEGKEVVSKNPVTDNNTSNEEARIKE
                     DSNQSQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKQLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPYGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANHADEKG
                     MISYYLVDPDKDASKYEKLGEISEDKLKNAKSPEENTNNNQAKDEDSKPDEKSSVEGE
                     ASLEINKTISTIREFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKGNIIAY
                     DDGSALQYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIEI
                     KATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKET
                     KAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGY
                     ALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQ
                     AVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKS
                     NVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWE
                     LRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDG
                     NVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRN
                     NGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTG
                     EVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKD
                     AGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQ
                     REDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVG
                     IFLGLKKKNQD"
     gene            complement(6948..7294)
                     /locus_tag="VQT45_001941"
                     /pseudo
     CDS             complement(6948..7294)
                     /locus_tag="VQT45_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7389..7574)
                     /locus_tag="VQT45_001942"
                     /pseudo
     CDS             complement(7389..7574)
                     /locus_tag="VQT45_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            7602..7829
                     /locus_tag="VQT45_001943"
     CDS             7602..7829
                     /locus_tag="VQT45_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2360206.1"
                     /translation="MRERLLTQPLLHADETSYRVLESHSHLTYYWTFLSGKVENQAIT
                     LYHHDQSRSGSVVQEFLGDYSGYVHCDMLRQ"
BASE COUNT         3028 a         1106 c         1548 g         2244 t
ORIGIN      
        1 taatcttatt ttttaacgtg tgctaaaaaa taaattaatg catgttaatt tttcttgaat
       61 taaatttttt taaatgatat actgttttta tggagagata acaattatat ataaatgtac
      121 tactctattt cctagataat acttagtaaa actttttata acaaaggcta gcaaagttaa
      181 agtttattat ctattggaag ttaaataaat atgtaaggaa ttaaaatgaa aaaaagtaca
      241 gtattgtcat taaccacagc tgcagttatt ttagcagcct atgcccctaa tgaggtagtc
      301 ttagcagaca catctagctc tgaagatgct ttaaacatct ctgataaaga aaaagtagta
      361 gtagataagg aaacagaaaa taaagagaaa catgaagata ttcataatgc tatagaaact
      421 tcacaggatt ttaaagagaa gaaaacagca gtcattgagg gaaaagaagt tgttagtaaa
      481 aatcctgtga cagacaataa cactagcaat gaagaagcaa gaatcaaaga agattccaat
      541 caatcccaag gagatcatac ggactcattt gtgaataaaa acacagaaaa tcccaaaaaa
      601 gaagataaag ttgtctatat tgctgaattt aaagataaag aatctggaga aaaagcaatc
      661 aagcaactat ccaatcttaa gaatacaaaa gttttatata cttatgatag aatttttaac
      721 ggtagtgcca tagaaacaac tccagataac ttggacaaaa ttaaacaaat agaaggtatt
      781 tcatcggttg aaagggcaca aaaagtccaa cccatgatga atcatgccag aaaggaaatt
      841 ggagttgagg aagctattga ttacctaaag tctatcaatg ctccgtttgg gaaaaatttt
      901 gatggtagag gtatggtcat ttcaaatatc gatactggaa cagattatag acataaggct
      961 atgagaatcg atgatgatgc caaagcctca atgagattta aaaaagaaga cttaaaagga
     1021 actgataaaa attattggtt gagtgataaa atccctcatg cgttcaatta ttataatggt
     1081 ggcaaaatca ctgtagaaaa atatgatgat ggaagggatt attttgaccc acatgggatg
     1141 catattgcag ggattcttgc tggaaatgat actgaacaag atatcaaaaa ctttaacggc
     1201 atagatggaa ttgcacctaa tgcacaaatt ttctcttaca aaatgtattc tgacgcagga
     1261 tctgggtttg cgggtgatga aacaatgttt catgctattg aagattctat caaacacaac
     1321 gttgatgttg tttcggtatc atctggtttt acaggaacag gtcttgtagg tgagaaatat
     1381 tggcaagcta ttcgggcatt aagaaaagca ggcattccaa tggttgtcgc tacgggtaac
     1441 tatgcgactt ctgcttcaag ttcttcatgg gatttagtag caaataatca tctgaaaatg
     1501 accgacactg gaaatgtaac acgaactgca gcacatgaag atgcgatagc ggtcgcttct
     1561 gctaaaaatc aaacagttga gtttgataaa gttaacatag gtggagaaag ttttaaatac
     1621 agaaatatag gggccttttt cgataagaat aaaatcacaa caaatgaaga tggaacaaaa
     1681 gctcctagta aattaaaatt tgtatatata ggcaaggggc aagaccaaga tttgataggt
     1741 ttggatctta ggggcaaaat tgcagtaatg gatagaattt atacaaagga tttaaaaaat
     1801 gcttttaaaa aagctatgga taagggtgca cgcgccatta tggttgtaaa tactgtaaat
     1861 tactacaata gagataattg gacagagctt ccagctatgg gatatgaagc ggatgaaggt
     1921 actaaaagtc aagtgttttc aatttcagga gatgatggtg taaagctatg gaacatgatt
     1981 aatcctaata aaaaaactga agtcaaaaga aataataaag aagattttaa agataaattg
     2041 gagcaatact atccaattga tatggaaagt tttaattcca acaaaccgaa tgtaggtgac
     2101 gaaaaagaga ttgactttaa gtttgcacct gacacagaca aagaactcta taaagaagat
     2161 atcatcgttc cagcaggatc tacatcttgg gggccaagaa tagatttact tttaaaaccc
     2221 gatgtttcag cacctggtaa aaatattaaa tccacgctta atgttattaa tggcaaatca
     2281 acttatggct atatgtcagg aactagtatg gcgactccaa tcgtggcagc ttctactgtt
     2341 ttgattagac cgaaattaaa ggaaatgctt gaaagacctg tattgaaaaa tcttaaggga
     2401 gatgacaaaa tagatcttac aagtcttaca aaaattgccc tacaaaatac tgcgcgacct
     2461 atgatggatg caacttcttg gaaagaaaaa agtcaatact ttgcatcacc tagacaacag
     2521 ggagcaggcc taattaatgt ggccaatgct ttgagaaatg aagttgtagc aactttcaaa
     2581 aacacggatt ctaaaggttt ggtaaactca tatggttcca tttctcttaa agaaataaaa
     2641 ggtgataaaa aatactttac aatcaagctt cacaatacat caaacagacc tttgactttt
     2701 aaagtttcag catcagcgat aactacagat tctctaactg acagattaaa acttgatgaa
     2761 acatataaag atgaaaaatc tccatatggt aagcaaattg ttccagaaat tcacccagaa
     2821 aaagtcaaag gagcaaatat cacatttgag catgatactt tcactatagg cgcaaattct
     2881 agctttgatt tgaatgcggt tataaatgtt ggagaggcca aaaacaaaaa taaatttgta
     2941 gaatcattta ttcattttga gtcagtggaa gaaatggaag ctctaaactc caacgggaag
     3001 aaaataaact tccaaccttc tttgtcgatg cctctaatgg gatttgctgg gaattggaac
     3061 cacgaaccaa tccttgataa atgggcttgg gaagaagggt caagatcaaa aacactggga
     3121 ggttatgatg atgatggtaa accgaaaatt ccaggaacct taaataaggg aattggtgga
     3181 gaacatggta tagataaatt taatccagca ggagttatac aaaatagaaa agataaaaat
     3241 acaacatccc tggatcaaaa tccagaatta tttgctttca ataaccaagg gatcaacgct
     3301 ccatcatcaa gtggttctaa gattgctaac atttatcctt tagattcaaa tggaaatcct
     3361 caagatgctc aacttgaaag aggattaaca ccttctccac ttgtattaag aagtgcagaa
     3421 gaaggattga tttcaatagt aaatacaaat aaagagggag aaaatcaaag agacttaaaa
     3481 gtcatttcga gagaacactt tattagagga attttaaatt ctaaaagcaa tgatgcaaag
     3541 ggaatcaaat catctaaact aaaagtttgg ggtgacttga agtgggatgg actcatctat
     3601 aatcctagag gtagagaaga aaatgcacca gaaagtaagg ataatcaaga tcctgctact
     3661 aagataagag gtcaatttga accgattgcg gaaggtcaat atttctataa atttaaatat
     3721 agattaacta aagattaccc atggcaggtt tcctatattc ctgtaaaaat tgataacacc
     3781 gcccctaaga ttgtttcggt tgatttttca aatcctgaaa aaattaagtt gattacaaag
     3841 gatacttatc ataaggtaaa agatcagtat aagaatgaaa cgctatttgc gagagatcaa
     3901 aaagaacatc ctgaaaaatt tgacgagatt gcgaacgaag tttggtatgc tggcgccgct
     3961 cttgttaatg aagatggaga ggttgaaaaa aatcttgaag taacttacgc aggtgagggt
     4021 caaggaagaa atagaaaact tgataaagac ggaaatacca tttatgaaat taaaggtgcg
     4081 ggagatttaa ggggaaaaat cattgaagtc attgcattag atggttctag caatttcaca
     4141 aagattcata gaattaaatt tgctaatcat gctgatgaaa aggggatgat ttcttattac
     4201 ctagtagatc ctgacaaaga tgcttctaaa tatgaaaaac ttggtgaaat ttctgaagat
     4261 aaactcaaaa atgcaaagag cccagaggaa aataccaata ataatcaagc taaggatgaa
     4321 gattcaaaac cagatgaaaa aagttcagtt gagggagaag ctagccttga aataaataaa
     4381 actatttcaa caattagaga gtttgaaaat aaagacctaa agaaactcat taaaaagaaa
     4441 tttagagaag ttgatgattt tacaagtgaa actggtaaga gaatagagga atacgattat
     4501 aaatacgatg ataagggaaa tattattgct tatgacgatg gtagtgcctt acaatatgaa
     4561 actgaaaaac ttgacgaaat aaaatcaaaa atttatggtg ttctaagccc atctaaagat
     4621 ggacactttg aaattcttgg aaagataagc aatgtttcta aaaatgccaa ggtatattat
     4681 ggaaatagct ataaatcgat agaaatcaaa gcgactaagt atgattcaca ttcaaaaacg
     4741 atgatatttg atttatacgc taatattaat gatattgtag atggattagc ttttgctgga
     4801 gatatgagat tatttgttaa agatgacaat caaataaaag ctgaaactaa gattagaatg
     4861 cctgaaaaaa ataaggaaac taaagcagaa tatccctatg tatcaagtta tgggaatgta
     4921 atcgaattag gagaaggaga tctttcaaag aacaaaccag acaatttaac taaaatggaa
     4981 tctggtaaaa tctattctga ttcagaaaaa caacaatatc tgttaaagga taacatcatt
     5041 ctaagaaaag gctatgcact aaaagtgact acctataatc ctggaaaaac ggatatgtta
     5101 gaaggaaatg gagtctatag caaggaagat atagcaaaaa tacaaaaggc caatcctaat
     5161 ctaagagtcc tttcagaaac aacaatttat gctgatagta gaaatgttga agatggaaga
     5221 agtacccaag ctgtattaat gtcggctttg gacggcttta acattataag gtatcaagtg
     5281 tttacattta aaatgaacga taaaggggaa gctatcgata aagacggaaa tcttgtgaca
     5341 gattcttcta aacttgtatt atttggtaag gatgataaag aatacactgg agaggataag
     5401 tccaatgtag aagctataaa agaagatggc tccatgttat ttattgatac caaaccagta
     5461 aacctttcaa tggataagaa ctactttaat ccatctaaat ctaataaaat ttatgtacga
     5521 aatccagaat tttatttaag aggtaagatt tctgataagg gtggttttaa ctgggaattg
     5581 agagttaatg aatcggttgt agataattat ttaatctacg gagatttaca cattgataac
     5641 actagagatt ttaatattaa gctgaatgtt aaagacggtg acatcatgga ctggggaatg
     5701 aaagactata aagcaaacgg atttccagat aaggtaacag atatggatgg aaatgtttat
     5761 cttcaaactg gctatagcga tttgaatgct aaagcagttg gagtccacta tcagttttta
     5821 tatgataatg ttaaacccga agtaaacatt gatcctaagg gaaatactag tatcgaatat
     5881 gctgatggaa aatctgtagt ctttaacatc aatgataaaa gaaataatgg attcgatggt
     5941 gagattcaag aacaacatat ttatgtaaat ggaaaagaat atacatcatt tgatgatatt
     6001 aaacaaataa cagacaagac actaaacatt aagattgttg taaaagattt tgcaagaaat
     6061 acaaccgtaa aagaattcat tttaaataaa gatacgggag aggtaagtga attaaaacct
     6121 catagggtaa ctgtgaccat tcaaaatgga aaagaaatga gttcaacgat agtgtcggaa
     6181 gaagatttta ttttacctgt ttataagggt gaattagaaa aaggatacca atttgatggt
     6241 tgggaaattt ctggtttcga aggtaaaaaa gacgctggct atgttattaa tctatcaaaa
     6301 gataccttta taaaacctgt attcaagaaa atagaggaga aaaaggagga agaaaataaa
     6361 cctacttttg atgtatcgaa aaagaaagat aacccacaag taaaccatag tcaattaaat
     6421 gaaagtcaca gaaaagagga tttacaaaga gaagatcatt cacaaaaatc tgattcaact
     6481 aaggatgtta cagctacagt tcttgataaa aacaatatca gtagtaaatc aactactaac
     6541 aatcctaata agttgccaaa aactggaaca gcaagcggag cccagacact attagctgcc
     6601 ggaataatgt ttatagtagg aatttttctt ggattgaaga aaaaaaatca agattaagac
     6661 aaaagctata gaaaaaaatg gtttatgtac tgagattaga tagtgaggtg atgacatagt
     6721 tttgtgaaaa cagccattta taactcaatt atttagttta cttcactatt gatactattt
     6781 ggagttatta atggacttag tttagataac taatgaattg attgaaaggg ttagtattga
     6841 caatattggt catattgatt agaaaataga gtctatcaaa atttaaaggc taatagaggt
     6901 gatgagacaa tttcggctct ttgtcaactg tagtgggttg aagtcagcta agctcgagaa
     6961 aggacaaatt ttgtcctttc ttttttgata ttcagagcga tgaaaatccg ttttttgaag
     7021 ttttcaaagt ttcgaaaacc aaaggcattg cgcttgataa gtttgatgag attattggtc
     7081 gcttccagtt tggcattaga atagtgtagt tgaagggcat tgacaatctt ctctttatct
     7141 ttgaggaagg ttttagagga tgaacctgat tcagattgtc ctcaatgagt ccgaaaaatt
     7201 tgtcaggctc cttattctga aagtgaaaaa gcaagagttg atagagatta tagtggtgtt
     7261 tcaagtcttc tgaatagctc aaaagtttat ctatagtaga ttgaaactag aatagtacac
     7321 ctctgcttct aaaacattgt tagaaatcga tttgactgtc ctgaatgatt tgtcctgtta
     7381 ttatttcatt ttactataaa tccacgttta cgaatctctt tccacacttg ttcaatgggg
     7441 ttcatctctg gtgtgtatgg aggaataaat gcaaaaccaa tattagtcgg aatctttaag
     7501 gtacttgatt tatgccatat agcattgtcc ataacgagta aaagataatc atctggataa
     7561 gcttgtgaaa gctcctattc ctaaagcccc tttataacct cttgcgagag agactattga
     7621 ctcagccctt acttcatgcg gatgaaactt cttatcgggt tctagagagt catagccatc
     7681 tgacctacta ttggaccttt ttgtctggga aagttgagaa tcaagcaatc acgctgtacc
     7741 atcatgatca gagtcggagt ggttcggtag tacaagaatt cctaggagat tattctggct
     7801 atgttcattg tgatatgttg cggcagtaac ttaggacttt agtcctctag ttctgcctat
     7861 gcgatagcag tccaaggttt aggagcaagg cgacgctaag cttggtaaac tgcgaactgc
     7921 tagaag
//
LOCUS       DAVAZT010000077         7489 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVAZT010000077 DAVAZT010000000
VERSION     DAVAZT010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7489
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.077"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..1038
                     /locus_tag="VQT45_001944"
     CDS             <1..1038
                     /locus_tag="VQT45_001944"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Produces ATP from ADP in the presence of a proton
                     gradient across the membrane. Subunit I is part of the
                     membrane proton channel; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HET2360207.1"
                     /translation="IKVMDERFGHSIYIYESETLSDNQDEIPIKLTNHSLIEPFELLT
                     EMYALPKYYEKDPTPVLAPFYFTFFGMMVADLGYGLLLFLGTMLALKIFHLPSETKRF
                     LKFFNILGVAVAIWGGIYGSFFGYELPFHLISTTSDVMIILVVSVVFGFITVFAGLLA
                     SGLQKVRMKKYAEAYNSGFVWCVILLGLLFIAVGMLMPDMRLLFVLGKWVSIFNAVGI
                     LVVSIIQAKSLSGIGAGLFNLYNISSYIGDLVSFTRLMALGLSGASIASAFNLIVGLF
                     PGTLAKLTIGLVLFILLHAINIFLSLLSGYVHGARLIFVEFFGKFYEGGGKPFQPLKA
                     SEKYIKVITKN"
     gene            1054..1530
                     /locus_tag="VQT45_001945"
     CDS             1054..1530
                     /locus_tag="VQT45_001945"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HET2360208.1"
                     /translation="MEHLATYFSTYGGAFFAALGIVLAVGLSGMGSAYGVGKAGQSAA
                     ALLKEQPEKFASALILQLLPGTQGLYGFVIGILIWLQLTPELPLEKGVAYFFVALPIA
                     IVGYFSAKHQGNVAVAGMQILAKRPKEFMKGAILAAMVETYAILAFVVSFILTLRV"
     gene            1564..2145
                     /locus_tag="VQT45_001946"
     CDS             1564..2145
                     /locus_tag="VQT45_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360209.1"
                     /translation="MSNLENLRESVIEQAHEKGRMKLLDSKKKIDDEFEMQKSVIVKK
                     KEVEHERKLKELQQKYQIIFQQLKNKERQSTLVSKQKILKELFQSALIEMESWSADKE
                     MEFIYRILERYSQQEVIVTFGERTLAKFNLEQLEKLKFSFPNHLFSEQPISNESGLLI
                     SIGKIDDNYLYKTLIGSISKEESSSIANQIFIN"
     gene            2210..3217
                     /locus_tag="VQT45_001947"
     CDS             2210..3217
                     /locus_tag="VQT45_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HET2360210.1"
                     /translation="MDTNLFSKINTTISVKENDFITEDKFQKIIQSKDTETMAFILEA
                     TPYHLSIDVLENPSQTETSLMTKLVNDYRWAYAESPSNKIVTLFALRYVYHNIKVLLK
                     SKAAIKKDFSKLLIPIGIFDIESLKHLVSSLHSDTLPDFMVHEVESIWNEYETFNNIR
                     VLDVGADLAYFKHLKLLSNELDEVLSQVIVAMIDFYNIITVKRGLSQNKSHGDILQLL
                     SDEGSISAKEFIYIVENQEIFVWFNKINPSLDSIFSTYELKMQDATISSSELEFLCDL
                     LLYKILDQGRYNVDGPLVLARYLLGCEFEVKNLRMIISALQNTIPFGSIKERIRPHYG
                     S"
     gene            3207..3527
                     /locus_tag="VQT45_001948"
     CDS             3207..3527
                     /locus_tag="VQT45_001948"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HET2360211.1"
                     /translation="MEANKYKIGIIGSRDIILPFSMIGFDIFPAYQEQEAINTLRKLA
                     QSDYGVIYITEDIASMILDTIRHYDSQVVPAIILLPTHKQGLNLGLKRIEDNVEKAVG
                     HNIL"
     gene            3590..5365
                     /locus_tag="VQT45_001949"
     CDS             3590..5365
                     /locus_tag="VQT45_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HET2360212.1"
                     /translation="MTQGKIIKVSGPLVIASGMQEANIQDICRVGKLGLIGEIIEMRR
                     DQASIQVYEETSGLGPGEPVVTTGEPLSVELGPGLISQMFDGIQRPLDRFKLATHNDF
                     LVRGVEVPSLDRDIKWHFDSTIAIGQKVSTGDILGTVKETEVVNHKIMVPYGVSGEVV
                     SIASGDFTIDEVVYEIKKLDGSFYKGTLMQKWPVRKARPVSKRLIPEEPLITGQRVID
                     TFFPVTKGGAAAVPGPFGAGKTVVQHQVAKFSNVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMQRTVLIANTSNMPVAAREASIYTGITMAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLEEMPGDEGYPAYLGSRIAEYYERAGRSQVLGIPEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYKDSVGIYIDGKE
                     KTDWNSKITRAMNYLQRESSLEEIVRLVGIDSLSDNERLTMEIAKQIREDYLQQNAFD
                     SVDTFTSFAKQEAMLSNILTFADQANHALELGSYFTEIMEGTVAVRDRMARSKYVSED
                     RLDEIKIISNEITHQIHLILETGGL"
     gene            5366..6751
                     /locus_tag="VQT45_001950"
     CDS             5366..6751
                     /locus_tag="VQT45_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HET2360213.1"
                     /translation="MSVIKEYRTASEVVGPLMIVEQVNNVSYNELVEIQLHNGEIRRG
                     QVLEIHEDKAMVQLFEGSSGINLEKSKIRFAGHALELAVSEDMVGRIFNGMGKPIDGG
                     PDLIPEKYLDIDGQAINPVSRDYPDEFIQTGISSIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDENFAVVFAAMGITFEEAEFFMEELRKTGAIDRSVLFMNLAND
                     PAIERIATPRIALTAAEYLAFEKDMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLVGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSHE
                     LYNQGYRPPINVLSSLSRLKDKGSGEGKTRGDHAPTMNQLFAAYAQGKKVEELAVVLG
                     ESALSDVDKLYVRFTKRFEEEYINQGFYKNRNIEDTLNLGWELLSILPRTELKRIKDD
                     LLDKYLPLVEV"
     gene            6774..7385
                     /locus_tag="VQT45_001951"
     CDS             6774..7385
                     /locus_tag="VQT45_001951"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HET2360214.1"
                     /translation="MVRLNVKPTRMELNNLKERLKTAERGHKLLKDKRDELMRRFISL
                     IRENNRLRKEVESYLIDNLKSFAVAKSLKNSLMVEELFSIPSKEIELFIEKENIMSVT
                     VPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIDKLLRLAEVEKTCQLMADEIE
                     KTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK"
BASE COUNT         2458 a         1042 c         1525 g         2464 t
ORIGIN      
        1 ataaaagtta tggatgagcg ttttggacat tctatttata tttatgaatc ggaaacattg
       61 tcggataatc aagatgaaat acctatcaaa ttaacgaatc attctttaat tgaaccattt
      121 gaattattga cagaaatgta tgctctgccc aaatattatg agaaagatcc tacacctgta
      181 ttagcaccat tttactttac attttttgga atgatggttg ctgatttagg ctatggttta
      241 ctattgtttt taggaacaat gttagcatta aaaatttttc atctaccttc agaaactaag
      301 agatttttaa aattctttaa tatattaggg gtagccgttg caatttgggg tggaatctat
      361 ggctcatttt ttggatatga gttgccattt catctgatat ctacaacctc tgatgtcatg
      421 attatattag tagtgtcagt tgtgtttggg tttattacag tatttgcagg tttgttagct
      481 tcaggactac aaaaagtaag aatgaagaaa tatgcagaag catataattc aggatttgtg
      541 tggtgtgtta ttctgcttgg cttgttattt attgctgtcg gaatgttgat gcctgatatg
      601 agactgttat ttgtattagg gaaatgggta tctattttta atgctgtggg aattttggtt
      661 gtttctatta ttcaagccaa aagcttgtca ggtattggag caggattgtt taatctatat
      721 aacatttcat cttatatagg tgatttagtt agtttcactc gattgatggc attaggatta
      781 tctggagcaa gtatagcatc agctttcaat ttaattgttg gtttgtttcc gggaacattg
      841 gctaaactaa caattggatt agtattattc attcttttac atgcgatcaa tatttttcta
      901 tcgttactat caggatatgt tcatggagca cgtctgatat ttgttgaatt ttttggtaag
      961 ttttatgagg gtggaggaaa accatttcaa cctttgaagg cttctgagaa atatattaag
     1021 gttattacaa agaattaatg gaggatatat ataatggaac atttagcaac ttatttttca
     1081 acctatggag gagctttctt cgctgcattg ggaattgtat tggcggttgg attaagtggt
     1141 atggggtctg cttatggagt tggtaaggct gggcaatctg ccgcagcttt actgaaagaa
     1201 cagccagaaa agtttgcctc tgctttgata ttgcaattac tgcccggaac acaaggatta
     1261 tatggttttg ttattggaat tttgatttgg ttgcaattaa ctccagaact tcctttagaa
     1321 aaaggcgttg cttatttctt tgtagctctt ccaattgcta ttgtaggata cttttcggct
     1381 aagcatcaag gaaatgtagc agtagcggga atgcaaatct tggctaaaag accaaaagaa
     1441 ttcatgaagg gagcaatttt ggctgccatg gtagaaacct atgcaattct tgcctttgtc
     1501 gtatcattca ttttgaccct tcgtgtataa gaaattaatt tgctattcaa aggaggtgtc
     1561 taaatgagca atttagaaaa cttacgagag tctgttattg aacaagctca tgaaaaaggg
     1621 cgtatgaaat tattggattc caaaaagaag attgatgatg aatttgaaat gcaaaagtcg
     1681 gtcattgtaa agaaaaaaga agtggaacat gaacgaaagt taaaagaatt acaacagaaa
     1741 tatcaaataa tttttcaaca attaaaaaat aaggaacgcc aatcaacgtt agtatcaaaa
     1801 cagaaaatat taaaagaact ttttcaatct gctttaatag aaatggaatc ttggagtgca
     1861 gataaagaaa tggagttcat ctatcgaatt ctggaacgat attcacaaca agaggtcata
     1921 gtaacttttg gggagcggac tttagctaaa ttcaatctgg aacaattaga gaaattgaaa
     1981 ttctcttttc caaatcattt atttagtgaa cagcctatct caaatgaatc aggcttactt
     2041 atttcaatag gtaaaattga tgataactat ttgtataaaa cattaattgg atcgatttct
     2101 aaggaagaaa gttcaagtat cgcaaatcaa atttttatca attaaggatg aaattggtta
     2161 atccttctta gaaatttgga gtattccaat aaaattagaa aggtatttta tggatactaa
     2221 tcttttttca aaaataaata cgacgatttc ggtaaaagaa aacgatttta ttacagaaga
     2281 taaatttcaa aaaattatac aatccaaaga tacggagaca atggcattta tcttagaagc
     2341 aactccctat catttatcga ttgacgtttt agaaaatcct agtcagacag agacttcgct
     2401 aatgacaaaa ttagtcaatg attatagatg ggcctatgct gaaagtccgt ctaataaaat
     2461 tgtgacttta tttgctttac gatatgttta tcataatatc aaagttttat taaaatctaa
     2521 ggcggcaatt aagaaagatt tttctaaatt attaattcca atagggattt ttgatataga
     2581 aagtttaaaa catttagttt cttccttaca ttcagataca cttcctgatt ttatggttca
     2641 tgaagtagaa tcaatttgga atgagtatga aacttttaat aatattcgtg tacttgatgt
     2701 cggagctgat ctagcatatt ttaaacatct gaaactttta tctaatgagt tagatgaggt
     2761 gctgtctcag gttattgtcg caatgattga cttttataat attattactg taaaacgtgg
     2821 tttatctcaa aataagagtc atggggatat tttacaatta ctttcagatg aaggaagtat
     2881 ttctgctaaa gaatttatat acattgtaga aaatcaagaa atatttgtgt ggttcaataa
     2941 aataaatcca agcttagatt caatcttttc aacttatgaa ttgaagatgc aggacgcaac
     3001 aatttcatct tctgagttag aatttttatg tgatttatta ttgtataaaa ttttagatca
     3061 aggaaggtac aatgtagatg ggccgttagt acttgctaga tatttattgg gatgtgagtt
     3121 tgaagtaaag aatctcagaa tgattatatc agctcttcaa aatacaattc cctttggatc
     3181 aataaaagaa aggatacgcc cgcattatgg aagctaataa gtataaaatt ggcataattg
     3241 gtagccgtga tattatttta ccctttagca tgattgggtt tgatatattt cctgcctatc
     3301 aagaacaaga agctataaat actctaagaa aattagccca atctgattat ggtgtcattt
     3361 atatcactga agacattgct tcaatgatat tagatacaat tcgccattat gattctcaag
     3421 ttgtgcctgc tattatttta ttaccgactc ataaacaagg tttaaattta ggattaaaac
     3481 gtatagagga taatgtggag aaagcagtag gacacaatat tttataataa tgtacaaaat
     3541 tgtctgtaat attattctat aatttttgga cttagtaagg agaataactt tgactcaagg
     3601 gaagattata aaagtatcgg gacctctagt tattgcatca ggtatgcagg aggctaatat
     3661 tcaagatatt tgccgtgtag gtaagctagg gttaatcggt gaaattattg aaatgagaag
     3721 agatcaggca tctatccaag tctatgagga aacatctggt cttggtccgg gagaacctgt
     3781 tgttacaact ggagaacctc tctcggttga attaggacca ggattgattt ctcaaatgtt
     3841 tgatggcata caacgcccat tagatcgatt taaattggct actcataatg attttctagt
     3901 tcgtggggta gaagttccaa gtttggatag agatattaag tggcattttg attccactat
     3961 agcaattggt caaaaagtga gtacgggtga tattctagga actgtcaagg aaaccgaggt
     4021 agttaatcat aaaattatgg ttccttatgg agtatctggc gaagtcgttt ctatcgcatc
     4081 tggcgatttt acaattgatg aagttgtata tgaaataaaa aaattggacg gtagtttcta
     4141 taaaggaacg cttatgcaaa aatggcctgt tcgcaaggcg cgtcctgttt ctaaacgttt
     4201 aatcccagaa gaaccattaa tcacaggtca acgagttatt gatacattct ttccagtaac
     4261 caaaggggga gcagcagctg ttcctggacc gtttggagca ggaaagacag ttgtacaaca
     4321 ccaagtagct aaattttcca atgttgatat tgttatttat gtcggttgtg gagaacgtgg
     4381 aaatgaaatg acggatgtac tgaatgagtt tcctgagttg attgacccta ataccggaca
     4441 atcaattatg caacggacag ttctgattgc taatacttca aatatgcctg ttgctgctcg
     4501 tgaggcttca atttatacag gaattaccat ggctgagtat tttcgtgata tgggctactc
     4561 tgtcgccatt atggctgatt cgacttcacg ttgggcagaa gcactacgtg aaatgtcagg
     4621 acgtctagaa gaaatgcctg gtgatgaggg ttatcctgct tatctgggaa gtcgtatcgc
     4681 tgaatattat gaaagagcgg gacgttctca ggttctaggg attccagaac gtgaaggaac
     4741 tattactgct attggagctg tatcgccacc cggtggagat atttcagaac cagttactca
     4801 aaacacttta cggattgtga aagttttttg ggggcttgat gctccgttgg cacagagacg
     4861 tcattttcct gcaattaact ggcttacatc ttattcactc tataaagaca gtgtgggaat
     4921 ttatatagat ggtaaagaga agacagattg gaatagtaaa ataactcgtg cgatgaacta
     4981 cttacaacgg gaatctagtt tagaggaaat tgttcgtctt gttggaattg attctctgtc
     5041 tgataatgaa cgactaacga tggaaattgc taaacaaatt cgagaagatt atttgcaaca
     5101 gaatgctttt gattcagtag atacattcac ttcgtttgca aaacaagaag caatgctaag
     5161 taatatccta acttttgctg atcaggcaaa tcatgcttta gagttaggtt cttactttac
     5221 agagattatg gaaggtaccg tggcagttcg agaccgtatg gcgcgaagta aatatgtttc
     5281 agaagataga ttagatgaaa tcaaaattat ttcaaatgag attacacatc aaattcattt
     5341 gatattagaa acaggaggtc tataaatgag tgttataaaa gaatacagaa ctgctagtga
     5401 agttgttggg cctcttatga ttgttgaaca agtaaataat gtgtcttaca atgagttagt
     5461 tgaaattcaa cttcataatg gagaaattcg tcgtggacaa gttttagaga ttcacgaaga
     5521 taaagcaatg gttcaacttt ttgaaggatc tagtggaata aatttagaaa agtctaaaat
     5581 tcgttttgct ggtcatgcac tagaattggc tgtatctgag gatatggttg gtcgtatttt
     5641 taatgggatg ggaaaaccaa ttgatggtgg accagattta attccagaga aatatttaga
     5701 tattgatggt caagctatta atcctgtatc tagagattat ccagatgaat ttattcagac
     5761 agggatctcc tctattgatc atttgaatac tcttgtacgt ggtcaaaaat taccagtatt
     5821 ttcaggttcg ggcttacctc ataatgaatt agcagctcag atagcaagac aagcgactgt
     5881 tttaaattct gatgaaaatt ttgcggttgt atttgcagca atgggtatta cttttgaaga
     5941 agctgagttt tttatggaag aactcagaaa aacaggagcg atcgatcgtt cagtcttatt
     6001 tatgaacttg gcaaatgatc ctgcaattga gcgtattgca actccccgca ttgctttaac
     6061 cgcggcagag tatctagctt ttgaaaaaga tatgcacgtt ctagttatca tgacggatat
     6121 gactaactat tgtgaagcgt tacgtgaagt ctcggcagcg cgccgtgaag ttccaggtag
     6181 acgaggctat ccgggatatt tatatacaaa tttatcaact ctatatgaaa gggctggtcg
     6241 cttagttggt aaaaaaggtt cagtgacaca gattcctatt ttaacaatgc cagaagatga
     6301 cataacacat ccaattcctg atttaactgg atacattact gaagggcaaa ttattttgtc
     6361 tcatgagttg tataatcaag gttatcgtcc accaatcaat gttttatctt ctctctctcg
     6421 attaaaagat aagggatctg gagaaggtaa aactcgtgga gatcatgctc caactatgaa
     6481 tcaactgttt gcagcctatg cccaagggaa aaaggttgaa gagttagcag tagtattagg
     6541 agaatcggct ttatctgatg tagataaatt gtatgtgaga tttacaaagc gttttgaaga
     6601 agagtacatc aaccaaggat tttataaaaa tcgaaatata gaagatacgt tgaatcttgg
     6661 gtgggaatta ctatcaattc ttcctagaac agagttaaaa cgtatcaaag atgatttgct
     6721 tgataaatat ttacctttgg tagaagttta atccagaaat ggagtgatta tctatggtac
     6781 gtttgaatgt aaaaccaact cgtatggaat tgaataactt aaaggaacgt ttgaaaacag
     6841 ctgaacgtgg acataagtta ttaaaggata aaagagatga attgatgagg cgatttattt
     6901 ctttgattcg tgagaataat cgacttcgga aagaagtaga aagttatcta attgataatc
     6961 taaaatcttt tgcagttgct aaatcattaa agaactctct aatggtggag gaattatttt
     7021 caattccatc gaaagaaatt gaattattta ttgagaaaga aaatatcatg agtgtaacag
     7081 ttcctagaat gcatatgaat attacttctc aaaatgagaa cagtgaatac agctatttat
     7141 cttctaatag tgaaatggat gatgtatttg ctacaatgaa tagtttaatt gataaattac
     7201 taagactggc agaagttgaa aaaacgtgtc agttaatggc tgatgaaata gaaaaaacac
     7261 gtagacgtgt aaatggttta gaatattcga ttattccaaa cttgtcggaa actattcatt
     7321 atatagaatt gaaactagag gaggcagaaa gagccaattt agttcgtatt atgaaagtga
     7381 agtagttcct ttatttagat ttttaattag atgaacaaat atcagcttgg ataaggcggt
     7441 aagcctttct aagctttttt aggctctttg tcaactgtag tgggttgaa
//
LOCUS       DAVAZT010000078         7474 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVAZT010000078 DAVAZT010000000
VERSION     DAVAZT010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7474
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.078"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            60..929
                     /locus_tag="VQT45_001952"
     CDS             60..929
                     /locus_tag="VQT45_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET2360215.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            933..1889
                     /locus_tag="VQT45_001953"
     CDS             933..1889
                     /locus_tag="VQT45_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET2360216.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKLPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            1889..2653
                     /locus_tag="VQT45_001954"
     CDS             1889..2653
                     /locus_tag="VQT45_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2360217.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            2653..3363
                     /locus_tag="VQT45_001955"
     CDS             2653..3363
                     /locus_tag="VQT45_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2360218.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKIPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            3828..4484
                     /locus_tag="VQT45_001956"
     CDS             3828..4484
                     /locus_tag="VQT45_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET2360219.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDESIDLPALREKFEANGIQVEEIARTSAKVL
                     "
     gene            4592..5687
                     /gene="prfB"
                     /locus_tag="VQT45_001957"
     CDS             join(4592..4663,4665..5687)
                     /gene="prfB"
                     /locus_tag="VQT45_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HET2360220.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            5705..6397
                     /gene="ftsE"
                     /locus_tag="VQT45_001958"
     CDS             5705..6397
                     /gene="ftsE"
                     /locus_tag="VQT45_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HET2360221.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            6390..7316
                     /locus_tag="VQT45_001959"
     CDS             6390..7316
                     /locus_tag="VQT45_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2360222.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
BASE COUNT         2208 a         1292 c         1682 g         2292 t
ORIGIN      
        1 agaacctatc aaaaagtgag ggaaaaccct cggaattata aatagaaaga gtgaatctta
       61 tgctccaaca actcgtaaat ggtttgattc taggtagtgt ttacgcgctg ttagccctag
      121 gatataccat ggtttacgga attatcaagc tcatcaactt cgcccatggt gatatttata
      181 tgatgggagc ctttatcggt tatttcttga tcaattcttt ccaaatgaat ttctttgtag
      241 cgcttattgt agctatgcta gcgacagcta ttcttggtgt cgtgattgag tttcttgctt
      301 accgaccttt gcgccactct actcgtattg ctgttttgat tacggctatt ggggtttctt
      361 tcctattgga gtatggaatg gtctatctgg ttggtgccaa tacccgtgcc ttccctcaag
      421 cgattcaaac agttcgatat gatttgggac caattagctt aacaaatgtg cagttaatga
      481 ttttggccat ttccttgatt ttgatgattt tgttacaagt cattgtccaa aagactaaga
      541 tggggaaagc catgcgtgca gtatcagtag atagcgacgc ggcgcaattg atggggatca
      601 atgtaaaccg tacgattagc tttaccttcg ctttgggttc tgctcttgcg ggtgcggctg
      661 gtgttctgat tgctctttat tataactctc ttgagccttt gatgggggtt actccaggtc
      721 ttaaatcttt cgttgccgca gtacttggtg gtatcggaat tattcctggt gcggctcttg
      781 gtggctttgt gattggtcta ttggaaacct ttgcgactgc ctttgggatg tcagatttcc
      841 gtgatgccat tgtttatgga atcttgttgt tgatcttgat tgtccgccca gctggtatcc
      901 ttggtaagaa tgtgaaagag aaggtgtaaa cgatgaagga aaatttaaaa gttaatattc
      961 tatggttact ccttttgtta gctggctata gcttgattag tgtactggtt tcagtcggag
     1021 tacttaatct attctatgta cagattttac aacaaattgg aattaatatt attttggctg
     1081 ttggtctcaa cttaatcgtt ggtttttcag gacaattttc acttggtcat gctggtttca
     1141 tggcgattgg tgcctatgca gcagctatta ttggttctaa attaccaacc tacggtgcct
     1201 tctttggagc tatgcttgta ggggctttgc tttcaggagc agttgcctta cttgtcggca
     1261 ttccaacctt gcgcttgaag ggggactatc ttgcggtagc aactctaggt gtttctgaaa
     1321 ttatccgtat ctttatcatc aatggtggaa gtcttacaaa tggtgcggca ggtatcttag
     1381 ggattcctaa ctttacaact tggcaaatgg tttacttctt tgtcgtgatt acaaccattg
     1441 caaccttgaa cttcttgcgt agcccaattg gccgttcaac cctctctgtt cgtgaagatg
     1501 aaatcgctgc tgagtcagtt ggggttaata cgactaaaat taaaatcatc gcttttgtct
     1561 ttggtgccat tactgcaagt attgctgggt cacttcaggc aggatttatc gggtctgttg
     1621 taccgaaaga ttacaccttc attaactcaa tcaacgtttt gattattgtt gtatttggtg
     1681 gactcggttc cattacaggt gcgattgttt cggctattgt tctgggaatt ttgaatatgc
     1741 ttctccaaga tgttgctagt gtgcgtatga ttatttacgc tttagccttg gtattggtaa
     1801 tgattttcag accaggtgga ctccttggaa cgtgggaact gagcctatca cgtttcttta
     1861 aaaaatctaa gaaggaggaa caaaactaat ggcattactt gaagtaaaac agttaaccaa
     1921 acattttggt ggtctaacag ctgttggaga tgtgactctt gaattgaacg aaggggaact
     1981 ggttggatta atcggtccaa acggagctgg gaaaaccacc cttttcaacc ttttgaccgg
     2041 tgtttatgaa ccaagcgagg gaacagtaac cctagatggt caccttttga atgggaaatc
     2101 accttataag attgcctctt tgggacttgg acgtactttc caaaatatcc gtctctttaa
     2161 agatttaaca gttttagata atgttttgat tgcttttgga aaccatcaca aacagcatgt
     2221 ttttactagt ttcttacgct taccagcttt ttacaagagt gaaaaagaat taaaggctaa
     2281 agctttggaa ttgttgaaaa tctttgattt agatggtgat gcagagactc ttgctaaaaa
     2341 tctttcctac ggacaacaac gtcgtttgga aattgttcgt gcccttgcta cggaacctaa
     2401 aattctcttc ttagatgaac cagcagcagg tatgaaccca caggaaacag ccgaattgac
     2461 tgagttaatt cgtcgtatca aagatgaatt taagattaca atcatgttga ttgaacacga
     2521 tatgaatctg gtcatggaag taacagaacg tatctacgta cttgaatatg gccgtttaat
     2581 tgctcaagga actccagacg aaattaagac caataaacgc gttatcgaag cttatctagg
     2641 aggtgaagcc taatgtctat gttaaaagtt gaaaatcttt ctgtgcatta cggtatgatc
     2701 caagcagtcc gtgatgtaag ctttgaagtt aatgaaggag aagttgtttc ccttatcggt
     2761 gccaacggtg caggtaagac aactattctt cgcaccttgt caggtttggt tcgaccaagt
     2821 tcaggaaaga ttgaattttt aggtcaagaa atccaaaaaa taccagctca gaaaatcgtg
     2881 gcaggtggtc tttcacaagt tccagaagga cgccacgtct ttcctggctt gactgttatg
     2941 gaaaatcttg aaatgggagc tttcttaaag aaaaatcgtg aagaaaatca agctaacttg
     3001 aagaaggttt tctcacgctt tcctcgtctt gaagaacgta agaaccaaga tgcagctact
     3061 ctttcaggag gggaacaaca aatgcttgcc atgggacgcg ctcttatgtc aacaccaaaa
     3121 cttcttcttt tagatgaacc atcaatggga cttgccccaa tcttcatcca agagattttt
     3181 gatatcattc aagatattca gaagcaagga acaaccgtcc tcttgattga acaaaatgcc
     3241 aataaagcac ttgcaatctc tgaccgagga tatgtattgg aaacaggaaa aatcgtccta
     3301 tcaggaacag gaaaagaact cgcttcatca gaagaagtca gaaaagcata tctaggtggc
     3361 taaaacaatc cagtggattg ttttagtcgg cagatgaaga ttacgaagta atcatcaata
     3421 tagtccgggg gcccttttta gtcggtagat tgagattgcg aagcaatcat caaatccaga
     3481 ggattgtttt agccggcaga taaagattac gaagtaatca tcaatatagt ccgggggccc
     3541 tttttagtcg gtggatgaag attgcgaagc aatcatcaaa tccagaggat tgttttagcc
     3601 ggtagattga gattgcaaac aaatctgcat ctacattgaa agcttaattt ctaataattg
     3661 aaaaaatcga atgaaaagtt tcttaccttc attcacagag ctcgatttta gagctctttt
     3721 tgctagctta ttcatacttt tctaaatttt gaaaaagaaa tgtaagcgtt tgatagattt
     3781 gcaaaaagat tgtataatag ggataagaat agaaaaggag aagtctcatg gcagttaaag
     3841 attttatgac ccgcaaggta gtttatatta gtccagatac aacagtatct catgcagcag
     3901 atttgatgag agagcaaggt ttgcaccgtc tgcctgttat cgaaaatgat caattggttg
     3961 gtttggtgac tgagggaacc attgcacaag caagtccatc taaagcaaca agtctttcta
     4021 tctatgagat gaattatctt ctgaataaga caaaagtaaa agatgtcatg attcgcgatg
     4081 ttgtcactgt ctcaggctat gctagtctag aagatgcaac ttatctgatg ttgaaaaata
     4141 agattggtat tctccctgtc gtagataacc atcaagtata cggagttatt actgaccgtg
     4201 acgttttcca agcctttctt gaaattgcag gttatggcga agaagggatt cgtgtacgct
     4261 ttgttacaga agatgaagtt ggtgttcttg gaaaaattgt ttctttgatt gtagaagaaa
     4321 atttgaatat ctcccataca gtcaatattc cgcgtaagga tggtaaggtg attatcgaag
     4381 tgcaaatcga tgaatcaatt gatttaccag ccttgagaga aaaatttgaa gcaaatggta
     4441 ttcaagtgga agaaatcgct cgcacttcag caaaagtctt gtaagaaggg aagtccaaag
     4501 gcttcttttt tcatgaaaag gggattagag caaaagatgg aaagaaatga taaaatatgc
     4561 tataatgaaa taatgtaaaa aaggagtatt tatggacatt tcagtaattc gtcagaaaat
     4621 tgacgcaaat cgtgaaaaat tagcttcttt cagggggtct ctttgacctc gaagggctag
     4681 aggaagagat tgccatcttg gaaaacaaga tgacagaacc tgatttttgg aacgataata
     4741 ttgcggccca aaaaacgtcg caagaattga atgaattaaa aaacacttac aataccttcc
     4801 ataagatgga agagttgcag gatgaagtcg aaattttatt ggattttttg gctgaagacg
     4861 agtcagtgca tgatgaactg gtagcgcagt tagccgaact tgataagata atgaccagct
     4921 acgagatgac tctactcttg tcagaacctt atgaccacaa caatgccatc ttggaaatcc
     4981 atccaggttc tggtggtact gaggcgcagg actggggtga tatgttgctt cgtatgtata
     5041 ctcgttatgg taatgctaaa ggctttaaag tggaagtgtt ggattaccaa gcaggtgatg
     5101 aggctggtat taagtcggta actttatcat ttgaagggcc taatgcctat ggtctcctca
     5161 agtcagaaat gggtgttcac cgcttagtgc gaatctcacc atttgactct gccaaacgtc
     5221 gccatacctc tttcacatct gtagaagtga tgccagaatt ggatgatact attgaagtgg
     5281 aaatccgtga agatgatatc aagatggata ccttccgttc aggtggtgcc ggtggacaaa
     5341 acgtcaataa ggtttcaaca ggtgtacgtt taacccacat tccaactgga attgttgtcc
     5401 aatcaacagt ggatcgtacc cagtatggaa atagagatcg tgccatgaag atgttgcagg
     5461 ctaagctcta tcaaatggag caagataaga aggctgcgga ggtagattct ctcaaaggtg
     5521 agaaaaagga gatcacttgg ggaagccaaa tccgttctta tgtcttcacg ccttatacta
     5581 tggtaaaaga tcaccgaact agctttgagg ttgctcaggt agataaggtt atggatgggg
     5641 acctagatgg ttttatagat gcttatctca agtggcgaat tagctaagat agaaaggaac
     5701 tcacatgtca attattgaaa tgagagatgt cgttaaaaaa tacgacaacg gaacgactgc
     5761 tctacgcggt gtttcggtca gcgttcaacc gggggaattt gcttacatcg taggaccttc
     5821 aggagcaggg aagtcaactt ttattcgttc tctgtatcgt gaagtaaaaa tcgataaagg
     5881 aagtctatca gttgctggtt ttaatctggt taagatcaaa aagaaagatg tcccgcttct
     5941 acgtcgtagt gttggggttg tcttccaaga ttataaattg ttaccaaaga aaactgtcta
     6001 tgaaaatatt gcttacgcta tggaagtaat cggggaaaat cgccgtaata tcaaaagacg
     6061 agtgatggaa gttttggact tggttggatt gaagcataag gttcgttctt tcccaaatga
     6121 actctcaggt ggggagcagc agcgaattgc gattgcgcgt gcaattgtaa ataatcccaa
     6181 agtattgata gctgatgagc caacaggaaa tctggatccg gataattcat gggaaattat
     6241 gaatctcttg gaacggatta acctacaagg gacaactatt ttgatggcga ctcataatag
     6301 ccagattgta aataccttgc gccaccgtgt cattgccatt gaaaatggcc gtgtcgttcg
     6361 tgacgaatca aaaggagagt atggatacga tgattagtag attttttcgc catttatttg
     6421 aagccttaaa aagtttgaaa cgaaatggtt ggatgacagt agctgctgtc agttcagtca
     6481 tgattacttt gaccttggtg gcaatatttg catctgttat tttcaataca gcgaaactag
     6541 ctacagatat tgaaaataat gtccgtgtag tagtttatat ccgaaaggat gtggaagata
     6601 atagtcagac aattgaaaaa gaaggtcaaa ctgttacaaa taatgactac cacaaggtat
     6661 atgattcttt gaagaacatg tctacggtta aaagtgttac cttttcaagt aaagaagaac
     6721 aatatgaaaa attaaccgag ataatgggag ataactggaa aatctttgaa ggagatgcca
     6781 atcctctcta tgatgcctat attgtagagg caaacactcc aaatgatgta aaaactatag
     6841 ccgaagatgc taaaaaaatt gaaggtgtct ctgaggttca agatggcggt gccaatacag
     6901 aaagactctt caagttagct tcatttatcc gtgtttgggg actagggatt gctgctttgt
     6961 taatttttat cgcagttttc ttgatttcaa ataccattcg tattaccatt atttcccgca
     7021 gtcgcgaaat tcaaatcatg cgcttggttg gagctaaaaa cagttatatc cgtggaccgt
     7081 tcttgttaga aggagccttt atcggtttat tgggagctat cgcaccatct gttttggtct
     7141 ttattgttta tcaaattgtt taccaatctg tcaacaaatc gttggtaggg caaaatctat
     7201 ccatgattag tccagattta tttagtccgt tgatgattgc cctactattt gtgattgggg
     7261 ttttcattgg ttcattggga tcaggaatat ccatgcgccg attcttgaag atttaggtaa
     7321 aatagctgct tttatgagga gattgtaaaa tctccttttt tgctacaaga gtttttgaaa
     7381 agagatgcgt agaagaaaag agcttccaaa gaagtccccc agagaagact tcttgatggc
     7441 taatttgaac ttgaaatttg gcgcactaga aatt
//
LOCUS       DAVAZT010000079         7220 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVAZT010000079 DAVAZT010000000
VERSION     DAVAZT010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7220
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.079"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            231..645
                     /locus_tag="VQT45_001960"
                     /pseudo
     CDS             231..645
                     /locus_tag="VQT45_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720030.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(684..1127)
                     /locus_tag="VQT45_001961"
     CDS             complement(684..1127)
                     /locus_tag="VQT45_001961"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HET2360223.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(1157..3379)
                     /locus_tag="VQT45_001962"
     CDS             complement(1157..3379)
                     /locus_tag="VQT45_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HET2360224.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRMIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            3790..4032
                     /locus_tag="VQT45_001963"
     CDS             3790..4032
                     /locus_tag="VQT45_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360225.1"
                     /translation="MTRFEEIFEEYKNPQDTFFYPLVYKENTYEKTAISIFALLMLGV
                     CCLFLFSQQSYKKLVQYYANDQNLPSRITYSEYSDK"
     gene            4372..5001
                     /locus_tag="VQT45_001964"
     CDS             4372..5001
                     /locus_tag="VQT45_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET2360226.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            complement(5124..7016)
                     /gene="pepO"
                     /locus_tag="VQT45_001965"
     CDS             complement(5124..7016)
                     /gene="pepO"
                     /locus_tag="VQT45_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HET2360227.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
BASE COUNT         1985 a         1681 c         1378 g         2176 t
ORIGIN      
        1 ttatcatttt atgacaaaca tactatcgtt aaatgctgat ttaatcgaaa ttttgagtta
       61 taaactcctc agtttcgaac tcaaaattag ccgtgcagga taggataccc ttcataaact
      121 tatataacta ctttaatacc ttaaaaagct aataaaataa ggaatatcta agcaatatac
      181 attctaaaat acctgtacgg gagtgtctct aaagaaaagg aggttttagc atgaaaaaaa
      241 tcatcttcat caaaaccatt caactccttg tcattgatgg aatcatgctg gcatttttga
      301 catttaaaag gggggcttac ttgggactgg attttgattt atagtggttg gctcattttc
      361 tttcatcctg tgctattgac ctatctttca aaccaacttt gtgaccactt tagtcaactc
      421 tattcccaga ttagaccgag attctggcgt tttgctttac aaattctcct atgggatagc
      481 ctgatgattc tctccttggt gtctttaagt gatattccac ttttccttca gggaactctc
      541 ctcatcctag gacatctcat cccttcctat cgcatctgcc aaagcctgaa aagagacttc
      601 ccccaagcat atcaagaacc gatttctttt tggagtattt tatgatcgat gagaaagacc
      661 aagccgactg ggcttggtct ttcttatctc tttttagtat ctaggataat ggtaacaggt
      721 ccgttattaa ccagctcaac ctgcatatct gctccaaaga tacctgtctg aacgggcact
      781 tcttgcgcta atttttgatt gaaagcatca tagaagtctg atgccatatc aggtttagct
      841 gcccctgtaa aggctggacg attgcctttc ttagtatccg caaagagggt aaactgagaa
      901 atagagagga tttctccttc aatatctttg acagacaggt tcatcttgcc ttctgcgtct
      961 gaaaaaatcc gcatattgac cagttttctc acagcatagt ccaaatcttc ctcttggtcc
     1021 tctggtccaa caccaaccag caataaaagt ccctgattga tttttccctg aatctggcct
     1081 tctatactca cttgggcttt tttaacccgt tggataatga ttttcataat agcctttcta
     1141 gtaagagcta ggacaactag ccgttggtcc gtttgacaga gtaaacttct ggcacactct
     1201 taattttatc gacaaccgtg gtcagtgtag agaggttggc aataccgaag gacacatgga
     1261 tattagcaaa cttcatatcc ttggttggtt gggcattgac cgttgaaata ttcttggttg
     1321 tatttgaaag aacttgcagt acatcgttca acagtcctgt acggttgaga ccgtagatat
     1381 cgatatgggc catatactcc ttatttgagc tagagtactg gtcttcccat tccacatcaa
     1441 ggagacgttg ctcgtagttt tcttgggcac gcaggttcat acagtccaca cggtgaatag
     1501 ccacaccacg acccttggta atgtagccaa caatatcgtc accaggcacg gggttacaac
     1561 acttagcaat ccgcactagg agaccagaag caccttcaat aaccactccc ccctcatgct
     1621 tgaccttgag agtttcttta ttttcaacct tgacctcgcc acctttgaca agctcctctg
     1681 cctcagcctt ggccttggca cgctcttcct cacggcgttc cttttcagtc agacggttaa
     1741 agacggtaat cgcaccgatt tccccaaaac caatggccgc aaagagggag tcttctgtct
     1801 tgtaactggt cttttgcaga acttgatcca tgtggcgctt gtccataaat ttatttgcca
     1861 catagccatt ttcttggaac tgagccatca gcatctcacg acccttgttg acagacaatt
     1921 ccttatcttg gtttttaaag aactggcgaa tcttattgcg cgccttgcta gtcttgacca
     1981 tattgagcca gtcacggcta ggtccaaagg agttcgggtt ggcgataatt tcaacctgat
     2041 cccctgtctt taacttggtt gtcagtggaa ccatgcggcc attgaccttg gcaccagttg
     2101 ctttttcacc gaccttggta tggatttcgt aggcaaaatc aatcggtcct gaatctttgg
     2161 gaagagaacg gacagctcca tctggggtaa aaacgtaaat ctcctcagcc agatagtttt
     2221 ccttaacaga gtccacaaat tccttagcat catcagcctg gtcttggagc tccatcatct
     2281 ccttgatcca gttcattcca atagctgatt ccttgctgtt aacttgcccc tttatacctt
     2341 tcttataagc ccagtgagcc gcaaccccgt actcagccac ctcgtgcatt tccttggttc
     2401 gaatctggaa ttcaatcggc ccttttggtc cataaacagt cgtatggata gactgataac
     2461 cattagcctt gcggttggca atatagtctt tgaagcgacc tggcatcggt ttccaaaatt
     2521 catgcacgta accaagcatg gcataaacat cactttgggt atctaaaata caacgaatag
     2581 caatcagatc atagatttcc tcaaaccgtt ttctcttgtc ctgcattttg cggaaaattg
     2641 agtaaatatg cttgggacga ccataaatct tccctttcaa gtgacgttct gtcgtatact
     2701 cctctaattt tgtgactacc tcatccacca aggcctcacg ctccctgcgc ttttccttca
     2761 tcatatgggt aatcttgtaa aactccgttg gattgagata acggaaagac aagtcttcta
     2821 attcccattt gacactggaa atccccaaac gatgggcaag cggggcatag atttccatgg
     2881 tttctttgga aatacgctcc tgcttgtctt ttcgaagatg tttcagggtc cgcatattgt
     2941 gcaagcggtc agacagtttg accaaaataa cgcggatgtc ctcagacatg gccatgagca
     3001 tcttgcgatg attttccgct aattgctcct cgatcgattt gtactcgacc ttgccaagct
     3061 tggtaactcc gtcaacaatc atccgcacat caggaccaaa ctctctttcc aaatcgtcca
     3121 aagtcgcatc tgtatcttcc accacatcat gcaagaatcc acaagctact gttacagcat
     3181 ccagctttag cttagctaaa atacctgcca cttggatagg gtgaatgata taaggctcgc
     3241 ctgatttgcg atattgacca ctgtggcatt caacagcata gaccaaggcc ttatggacaa
     3301 aatgaacatc ctcttccgtt aaatattctt tggttaaagc gacaacttct tcgcctgtta
     3361 aattcacttc tttcggcatc tctactctcc aattcttcct accattttat cactttttta
     3421 agaatatgaa aactagattg gaacagaata agaaaaaaat aattcaaaat tgcttgataa
     3481 ttctgaatta ttggcccata atatactacg aagttagatt ttaaacttag gtgatagaag
     3541 gagagataga agaacggaaa ccatattgta acccaaagac tttctgattt ccccaattcc
     3601 attgaagata cgaaagataa acggtggaac tcgtatcaca tacactggta ccttgactgg
     3661 attttggaat taatactcaa tgaaaatcaa agagcaaact aggaaactag ccacaggttg
     3721 ctcaaagcac tgctttgagg ttgtagataa gactgacaaa gtcagtcaca tatatacggc
     3781 aaggcgacgt tgacgcggtt tgaagagatt tttgaagagt ataaaaatcc tcaagatact
     3841 ttcttctatc ctttagttta taaggagaat acctatgaaa aaactgctat ttctatcttt
     3901 gctctcctaa tgttaggagt ttgctgcctg ttcctattca gccagcaaag ctataaaaaa
     3961 ctcgttcaat actatgctaa cgaccagaac ctgcccagta ggataactta tagtgaatat
     4021 agcgacaaat gagaagccaa ctacggtagc actctaaaca tcacgtctat caaacaagct
     4081 aatgacggag tttatgcaac ctatgaaggg caattgacac ctttccaata ttgataaatt
     4141 gataaccagc ctgtcttcat ctagtcatgc tggtttttaa gttcatttta aatccttacc
     4201 tattctccct aactgtgcta tacttaattt atactcaatg aaaatcaaag agcaaactag
     4261 aaagctagcc gcaggctgtt caaagcactg ctttgaggtt gcagataaag ttgacgcggt
     4321 ttgaagagat tttcgaagag tattagtaca ttctttgaga ttggagttag tatgaaaatc
     4381 cataaaaccg tgaatcctgt tgcctatgaa aatacctatt atctagaagg cgaaaagcac
     4441 ctcatcgtcg tcgatcctgg tagtcattgg gaagccattc gtcagacaat cgagaagatc
     4501 aacaaaccga tctgtgctat tctcttgacc cacgcccatt atgaccatat catgagtctg
     4561 gacttggttc gcgagacgtt tggcaatcct cctgtctata tcgcagagag cgaagccagc
     4621 tggctctaca ctcctgtcga taatctctcc ggtctccctc gccacgatga tatggcagat
     4681 gtggtcacaa aacctgcaga acacaccttt gtctttcacg aagaatacca actagaggaa
     4741 tttcgtttta aggttctacc gaccccaggg cactctatcg gtggtgtttc cctagtcttt
     4801 cctgatgctc acctagtctt gacgggagat gctctattcc gcgaaactat cggacggacc
     4861 gaccttccga ctggtagcat ggagcaactc cttcatagta tccagaccca actcttcacc
     4921 ctaccaaact acgatgtcta tccaggacat ggtccagcta ctactatcgc tcacgaaaag
     4981 gccttcaatc cctttttcta gcaagatgat gacaatcgaa atttaagtaa actatccagc
     5041 aaatctttct attacaaaag gcatcctatc aaggttttca cacgtgattg gatgcctttt
     5101 ttctgatgac tagatttttt gtattaccaa ataatcacgc gctcctctgg tgaacgccac
     5161 attccgtctc cttctttgac atcataggtt gtaaagaaat cgtcgaagtt tggtacttgc
     5221 acattgacac ggagtttggc tggtgcgtgc acatcgacgc tagccaaaag tttcataaat
     5281 tctggtcgac ctttcatgcg ccagatgcga ccgaagttgt agaagaactc ttctgctgag
     5341 aagtctgctt ctctcttagc tgcttcaagc gctgctgcga ttcctcccaa gtcagccacg
     5401 ttttctgata cagtcaattt accgttaatg gttgctccat aagaatcctg tccatcaaat
     5461 tggtcaatga ctttttgtgt tttctccttg aaggcagcat agtcgctctc tgtccaccaa
     5521 tccttgaggc taccattttc gtcaaaggaa gccccgttag tatcaaaggc gtgggaaatt
     5581 tcatgggcaa tcactgcccc aataccaccg tagttagcag aagatgactg atgcaagtca
     5641 tagaaaggcg cctgtaaaat ggccgctgga aagacaatca ggttcttctg aggattgtag
     5701 taggcattga ccatatgagc aggcatgccc cattccttat agtctacagg ctggttccac
     5761 ttactccaac tgtgcttgat ttccacacgc gcaaaggcta gagcattctc aaaaagactg
     5821 gcagtttcat tcactacctt atccttgtaa cgtgcaggca attcttctgg atagccaata
     5881 taaggtttga tcacattgag cttcacgata gcctgtttac aggtttctgg agtgagccag
     5941 tcattcttaa gcagacgctc cttatagaca tcaatcatgg ttgccacttt tttctccaca
     6001 tccgccttgg cttctggaga gaacttctca cgggcgtacc aaagccccag ggcttgcttg
     6061 aaaggttcct gtgctagatg ataagctgct ttgaccttat cttttgcctc tggaactcca
     6121 gaaagggcac ggctgtaggc accagacaaa acacggatat cctctgttaa atagctggtt
     6181 gaaagattga caacactcaa aatcaaggtt gctttaagga gagaccaggc ttcctcactg
     6241 taaaattgct ctgctgcttg ccagaaacgt tcctcgtcta caataacctt gtctggtaat
     6301 tgcccaataa ctgctttgaa gaagtcatcc aaaggtaggg caggcgcgaa tttcttgaaa
     6361 tcttcgtaag aatatggatg atagagttta gcatattctg aactttcttc attagagagc
     6421 accactgccg caactcggcg gtccaattca agtctttttt ctagcaagtc ttcaatttct
     6481 tcatcagaga aatcataagc cttgaggaga tttgcgctgc tttctttcca aagagtcaag
     6541 agctcttcgc gctgaggatg ttcttctgca tagtaggtcg tatctggcaa gattgtgctt
     6601 ggagcgctag cccatagaac attgattcta gcatccataa agtctggcga tacaccaaaa
     6661 ggaaggaagt ttggttttcc tgcaagctca aactctgcta gtttagctgt aaaatccgca
     6721 aaagtttcca attcttggaa ttctttaagg agtggtaaga caggtgtgat accgtcagct
     6781 tctctcttgt caaaatcacg aactaggcgg tggtatttga caaagttttc caagatagca
     6841 tcctcaggca cttcttcacc tgctaaccac ttgtctgttg tcgccagcat caggtcttca
     6901 atttcctggt ctaaatcaac aaaacctcct gtttgagact tatctgctgg gatttcagct
     6961 gtctgttgcc attctccatt gatagcatca taaaaatcat cttgataacg tgtcatcttg
     7021 ttctcgcttt catttgtatt tgcatttatc ttaacaaaaa tcactaggga atgcaattaa
     7081 taaccattta actattattt tttagctatt ataaaaaacc tttccatgat aaaacgcata
     7141 attccaagtt ttttacactt gatactatgc gttttataat ttagaaattt atcctgaaag
     7201 ttatctttag aatctatttt
//
LOCUS       DAVAZT010000080         7162 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVAZT010000080 DAVAZT010000000
VERSION     DAVAZT010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7162
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.080"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(741..1001)
                     /locus_tag="VQT45_001966"
     CDS             complement(741..1001)
                     /locus_tag="VQT45_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360228.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADIHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
     gene            complement(1060..1611)
                     /locus_tag="VQT45_001967"
     CDS             complement(1060..1611)
                     /locus_tag="VQT45_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360229.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIYEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(1601..1798)
                     /locus_tag="VQT45_001968"
     CDS             complement(1601..1798)
                     /locus_tag="VQT45_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360230.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(1802..2386)
                     /locus_tag="VQT45_001969"
     CDS             complement(1802..2386)
                     /locus_tag="VQT45_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360231.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEIPKELTPSEQLTWIAFLLPDGDIKQIKSVSNLLYGGAYALS
                     HSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(2794..3219)
                     /locus_tag="VQT45_001970"
     CDS             complement(2794..3219)
                     /locus_tag="VQT45_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360232.1"
                     /translation="MTSRVFIDADCISAFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVTKGSAEIVSIDIGTEEYALYRDLTRNYDSNKIIGKGEATSIFLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(3212..3706)
                     /locus_tag="VQT45_001971"
     CDS             complement(3212..3706)
                     /locus_tag="VQT45_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360233.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKEMVLGHYIKSTEQLLENNRISQGKYEELLLDAFRYDIVYGLDEEGE
                     LSFD"
     gene            complement(3752..3958)
                     /locus_tag="VQT45_001972"
     CDS             complement(3752..3958)
                     /locus_tag="VQT45_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360234.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLGR"
     gene            complement(3945..4106)
                     /locus_tag="VQT45_001973"
     CDS             complement(3945..4106)
                     /locus_tag="VQT45_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2360235.1"
                     /translation="MNMINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(4471..5427)
                     /gene="lytA"
                     /locus_tag="VQT45_001974"
     CDS             complement(4471..5427)
                     /gene="lytA"
                     /locus_tag="VQT45_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HET2360236.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPDFTVEPEGLITVK"
     gene            complement(5803..7155)
                     /locus_tag="VQT45_001975"
     CDS             complement(5803..7155)
                     /locus_tag="VQT45_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET2360237.1"
                     /translation="MDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVGRFLGQE
                     SLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWILGALLSI
                     LVMLLGFLGLYHLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLRSIGDSL
                     AALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRKSVPELL
                     PQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQTAARRI
                     MTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIFLFFASP
                     ALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPLVSSFIE
                     LIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAILATKVQS
                     "
BASE COUNT         2298 a         1486 c         1132 g         2246 t
ORIGIN      
        1 tggtttcgca ggaagtctat tatatatgca cagacatatg aaatcttttt gagacagcag
       61 ttatgatata tttatccatt cacaacatct tctgtactaa tactacaata ttggtacatt
      121 ttgattacac aatcgtttca aaaaatatga tggaagcctg agtattttat agtaattccc
      181 ttcctatcaa ctagatcaac cagttgagtg ttgaatgttg aaacacccta gcctcagcaa
      241 aggactatga tcagcatttc ctagccaata ggacgctcca aatcacctat tctaagtcca
      301 tcactagctt ggtcagtaag atacagactg caaggcgaga ctgacgtggt tgatgagatt
      361 ttggaagagt attacaatca tagattcacc agtagacttg accgcagatt taactatagt
      421 agattgaaac tagaatagta catctctgct tctaaaacat tgttagaaat cgatttgact
      481 gtcctgatca atttgtcctg ttctcgtttc atttcactat actaaaaaac cacctgaaac
      541 aaatcaagtg actagaggat aaaaacaaag actaggcaaa aagttttgaa aagcaaaaaa
      601 cgcataatat caggtcttga aaaaccttga tactatacgt ttgattgtgg gaagattgac
      661 ttcattttct cctgaaattg aagttttttc tagtttccag atatagacga attcaatata
      721 gccatctcgc tacaattatt ttaaccatcg agaaaatttt tcagaatttc aaaaatttca
      781 ttttgatcca atgaaatgtc atcattttga agaatagttg acttcacagg ctctaattct
      841 atcacaaagc ggtgtatgtc tgcttttacc gcactacttg atgttatagc cgataacttt
      901 tcatctccta gcaaggaagc tgtcaaacgg gtaaggtcat tcaaatgctt tttaatggac
      961 ttacttaaac cttgagcacc tgtagcagag cgttccctca tatccagcca agctttagcc
     1021 ttaaaaataa ttaatactca atgaaaatca aagagcaaac taggaagcta gctgcaggct
     1081 gctcaaaaca ctgttttgag gttgtagatg gaagctgacg tggtttgaag agattttcga
     1141 agagtataaa ccacaattac tcaataccga atacccctga atggtttctt tttcatgcac
     1201 caatatatta taataatctt catccaataa taaggctgat aaactagcat cttggtcaaa
     1261 atgtaaggga atttctcgac cgtccttctt taatggatat tctggtaaga tactaaatag
     1321 ttcaatcata gaaggaaact caggattagt tgttgtaaat cgaaaaagct gcgctttctc
     1381 atctttctga cttccttgat actctcccaa ttctaaaaaa tgattcaagg tagtataaaa
     1441 ttccttattt tttacttcat aaatgatgac catatcataa tcttttgttg tgcgactttt
     1501 aaatccttgc gaatccaata cgatagaggt agcagttccc ccaatcagaa cataatagtt
     1561 ctgaaaatcc gcaaacattt cttgaaaaat aactttcgta ttagctggca tcatcttctc
     1621 ccagatactg taatatcata ttttctagtg cttcactctc ttcctctata cgtgggtcat
     1681 catcatcttt taaggtcaaa taaagagaaa tcggatctac aaattgttta tcatgattat
     1741 ttttaaaatc attccaaaac tcagatacaa aaggacgata tttccatatc tctagcatct
     1801 ttcattttaa aacatgctga gaaagtggca aggataactg attgaatttt ctctgccata
     1861 tgacatagct agtattttca tccgtttcag ctaaaaaagt tgaatgcgac aaagcataag
     1921 caccaccata tagaaggtta gaaacagatt ttatctgctt tatatcgcca tctggcaata
     1981 aaaaggcaat ccacgttaat tgttcgctag gtgttaattc cttagggatt tcagtatcat
     2041 tcgcattgag tactagtccc aatggaggga agaagaggtt tcccttaaag tctacaaacg
     2101 gaactctagc ttgaagtaat tgcttttttt cactgtctga taacttcgaa aacaccaaaa
     2161 caacatccat attggctttt tcacccatag tgcgagcctg agtaacaaat gaactcaaac
     2221 tcccccttct cttttcttta atcaataaaa atgattcctt atgaaaagtc atttgagtat
     2281 actcaaacct ttttacaaaa ctgattggta aagtcaaagt cagttcctca atactgacat
     2341 caacataaaa ggattgaaaa attgacatta tctttttgac attcatgttt tttccttatt
     2401 ctatcatttt tattatattt tatcattcgg tataataaaa tataagtttt ttgataaaat
     2461 aaccaaaaac tactcgctat cccctctcac attaccctac atatcgtttg acatgcgact
     2521 gatagttcag gaaaacttca aggagaactt ttctctcatc cactatgcag gacttactat
     2581 ttcacttcta ctcctatagg ctcaatttga cacttttctt tttcgaattg ctcatatgcc
     2641 tcctgaatag tgagttcgat ttatccaaat ttatttttgt ctattttgat gaatacttcc
     2701 acgaagatag tctgaaaatg aatttgcacc aattttcctt ctctttttaa gcatattatt
     2761 ccagatatga ttgccctctt gttcagtaat aaattacgct ttaaacgctt caatcagtat
     2821 atctcctgtt gtcatatgtt ctaaagaaaa ttcttctaca tatggtttaa catctcttag
     2881 gttattactt cctaatatcc cattatgctt tttcgctaag aaaatagaag tcgcttctcc
     2941 cttaccaata atcttgttac tatcataatt tcttgttaaa tctctatata atgcgtattc
     3001 ttcagttcca atgtctatgc tcacaatctc agctgaaccc ttagttacca actggtctat
     3061 cctagatttt aaatggggaa ttgtaggtat attgatttca tcatacacct cttgtggaat
     3121 aacaatttta cccgaataga gcttttctaa aagatgttca gtgccaaccc ataaaaatgc
     3181 tgaaatacaa tctgcatcaa taaatacacg actagtcaaa cgacaactcc ccctcttcat
     3241 ctagcccata tacaatatca tatctgaaag catctagtaa cagttcctca tacttccctt
     3301 gcgaaattct gttattttct aaaagttgtt cagtcgattt aatatagtgc cctaatacca
     3361 tttccttttt actttctgac aaaggacgat ataaacttgt atcatagcct aatcttgaag
     3421 ctgtctctat aacactaata tccatatttt taatttcttc tgcatcaagg tatccatcat
     3481 ttctcaatct atataacata gctttatgac tgataccata aaactgaccc aattttataa
     3541 tatcttctac ttcaagatga gttctattgg cattttctct gatttcctca accatcctat
     3601 acagtgaaga tgggaaaatt aaaaaataag aagcaaactg atccgctttt ctttcagttt
     3661 catctccttc accaatcaag ataagactga ctgaactctt cttcacctca tcataataaa
     3721 gatgatacag tccatgtgct aaagaaaatc tttaccttcc taatggcatg tctgaattga
     3781 ctgcaatgag actgaactga gttcctttat aacagactcc gctaatattc tttccgagtc
     3841 cataaaatac cagcgtcaaa ttttctatct tttgtaccaa tttaaaaata tctatcggcg
     3901 attcaccatc agctcccaac ttttttctaa gatttgaagc tttattactt aaatccattc
     3961 gtgatattcc tttcaccttt ttccattttg gcaatcatgc tttgattcaa agacaaatac
     4021 tcagcaatct tatcttgagt aagatttgaa gatattctaa gttcttttat tctttttcca
     4081 acatcacata catttatcat attcatacac ctctcataaa aagaatagca cattcttgtc
     4141 ataatttttt aaataaaaaa attatgacaa aacaaggaag caatttattg atgctactta
     4201 aaaatctaaa attgatgata ttaaacctat ttgatgagtt cctatcaaaa atcgtatctt
     4261 caacctcaaa acagtactta aagctatccg actcggttta cattgtcaaa tttagatttt
     4321 atttgagcat aactttctag tttgcttttt gatttttgtt taatatagta acaaaaattg
     4381 aaggaaatat ctccacaaga aaacgcatac tattaagctt tttcaagacc taataatatg
     4441 cgctgttctg atttgaaaga cattccatta ttattttact gtaatcaagc cttcaggctc
     4501 tactgtgaag tctggcttgt ctgccagtgt tccgtctggt ttgaggtagt accagcctgt
     4561 tccgtccgct gactggataa aggcatttga taccatggcg ccttctttag cgtctaagta
     4621 gtaccaagtg tccttgtact tgacccagcc tgtcttcatg gcaccttctt cgttgaaata
     4681 gtaccactta tcagcgattt tcttccagcc tgtagccatt tcgcctgagt tgtcgaacca
     4741 gtaccagttg ccgtctgtgt gcttcctcca gcggtctgca agcatatagc ctgaactgtc
     4801 aaagtagtac caagtgccat tgattttctc aaacttgtct tttggataag agccgtctga
     4861 atgtacgtac cagtagccag tgtcattctt ctgccagcct gtttcaatcg tcaagccgtt
     4921 ctcaatatca tgcttaaact gctcacggct aatgccccat ttagcaagat atggataagg
     4981 gtcaacgtgg tctgagtggt tgtttggttg gttattcgtg caatactcgt gcgttttaat
     5041 tccagctaaa ctccctgtat caagcgtttt cggcaaacct gcttcatctg ctagattgcg
     5101 taagagttcg atataaaggc ggtagtccgt catgaactct tctttggttg aatggctttc
     5161 aatcagttca accgctgcat aggtctcagc attccaaccg cccccaacgt cccaggcacc
     5221 attatcaaca ggtcctacct gcatgatgca accgttccca acaatgtgcg agaaaaaacc
     5281 taattctggg tctttccgcc agtgataatc cgcttcattc tgtacggttg aatgcggatt
     5341 cccagttgag tgtgcgtgta cttgcctata tggttgcacg ccgacttgag gcaaatctgt
     5401 tcttaattta ctcacattaa tttccatatt ctactcctta tcaattaaaa caactcattt
     5461 tttacaatcc agaaccagaa actcctttat ttctacctta caaagaagac aatcttagtc
     5521 acgattaagc ttgtagatag aacctcaaaa cgcactattt tgacactgta aataggactg
     5581 acaaggtctg cattctatct acaataacac cccagactaa aaagcttttc aaaagtatat
     5641 ttttacagtc tctatatgtc cttttcataa atactatact ttattatatc acataaaaga
     5701 agtcaaaagt ctgttaaact attttcaaca ccaaactaaa gaagagaaca caagtttttt
     5761 cgatgttcac tagaggaaat ggattttatt cagtaaatcc aactaggatt gcactttggt
     5821 tgccaaaatt gcctttcctt cttttatcaa gggatgacgg aatagtgaga agtacagttg
     5881 aactgtcatg gcaacccaga taagaggttc acaaaggata acacccttat atcctgccca
     5941 aggaataatc aaaaccacaa aaacgatttt tccgattagt tcaataaagc tagaaactag
     6001 aggaaggatc ttctgcccca agccctgcaa gcaattgcga taaatcaaca agaggctcaa
     6061 aatgggataa aaggctgaac tgatttgcag atagagactt ccattttcta tcaagtaacc
     6121 atctgtcgaa ctagccaaga aggaaaccaa ggctggactg gcaaaaaaga ggaaaataca
     6181 aacaaaaact gcccaggata tacttaaacg actgccgatt cgaagacctt gaacaatgcg
     6241 gtcaggtcgc ttagctccta gattctgaga agcaaaggtc gtcattgatg cagaaatagc
     6301 ggtcatagga agaagggcaa aggtcataat gcgtcgagct gccgtctggg cactaataat
     6361 cactgcacca aatgtattaa cagaaaactg taaaatcaca ctgccgatag atacaattga
     6421 actcatcaag cccatagcca aaccttgctc caagagatcc gcgtacaagc ttttgtccca
     6481 tttgaaatgt ttaaactgtg gcaagagttc tggcacactt ttacgaatat aataaaagca
     6541 gagaaccgct gataaacctt gcgaaataat ggtagcaagt cctgcggatt gaactcccag
     6601 atgcaattgc gtaataaaat agagatccag aaccacatta accaaggcag agaaaatcag
     6661 aaatcccagg gctgctagac tgtcaccaat agaccgcaac aagcctgcaa aaagattata
     6721 agcaaagctg acacctacac aggtcacaat catagaaata tattgataag attgaggaag
     6781 aatttctgca ggagtatcta agtattgcaa gagatgatac aagccaagaa agcccagcaa
     6841 cataactaga atgctcaaaa gagcacctaa aatccaagta gctgctactg cttccttgat
     6901 tttagtgaaa ttccgagccc cataataacg agcaatgaca atccccatgc cattgccaac
     6961 accaagtgta aaacctacaa tcaggtcaaa aatcgctgtc gtcgctccta ctgcagccaa
     7021 ggattcttga ccaagaaatc gtccaacaat caagacatca gcagtgttat agagctgttg
     7081 aaaaatattt gatagcaaaa ttggaaaggt gaagcttaag agcgagggaa gaatcggacc
     7141 atgtatcagg tccactgttc gt
//
LOCUS       DAVAZT010000081         6863 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVAZT010000081 DAVAZT010000000
VERSION     DAVAZT010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6863
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.081"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..290
                     /locus_tag="VQT45_001976"
     CDS             <1..290
                     /locus_tag="VQT45_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2360238.1"
                     /translation="ETMTSDFFEVWFQKFFLPTLTTPSVIIMDNVRFHRMGKLELLCE
                     EFGHKLLPLPPYSPEYNPIEKTWVHIKKHLKKVLPSCNTFYEALLSCSCFN"
     gene            351..1313
                     /locus_tag="VQT45_001977"
     CDS             351..1313
                     /locus_tag="VQT45_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET2360239.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYDDTSISVSSNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVIIFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVEPLRYE"
     gene            1490..2497
                     /gene="gap"
                     /locus_tag="VQT45_001978"
     CDS             1490..2497
                     /gene="gap"
                     /locus_tag="VQT45_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HET2360240.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2564..3400)
                     /locus_tag="VQT45_001979"
     CDS             complement(2564..3400)
                     /locus_tag="VQT45_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET2360241.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQYLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETYVSRLKQFSNKTSLARCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            3526..5721
                     /locus_tag="VQT45_001980"
     CDS             3526..5721
                     /locus_tag="VQT45_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET2360242.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMASQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVAAVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIAYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5774..5926
                     /gene="rpmG"
                     /locus_tag="VQT45_001981"
     CDS             5774..5926
                     /gene="rpmG"
                     /locus_tag="VQT45_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET2360243.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            5936..6112
                     /gene="secE"
                     /locus_tag="VQT45_001982"
     CDS             5936..6112
                     /gene="secE"
                     /locus_tag="VQT45_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HET2360244.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6168..6704
                     /gene="nusG"
                     /locus_tag="VQT45_001983"
     CDS             6168..6704
                     /gene="nusG"
                     /locus_tag="VQT45_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HET2360245.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
BASE COUNT         2135 a         1192 c         1491 g         2045 t
ORIGIN      
        1 aagagacgat gacgagcgac ttttttgaag tatggtttca gaagtttttc ttaccaacat
       61 taaccacacc atcggttatt attatggata atgtaagatt ccatagaatg gggaagctag
      121 aactcttgtg tgaagagttt gggcataaac ttttacctct tcctccctac tcacctgagt
      181 acaatcctat tgagaaaaca tgggttcata tcaaaaagca cctcaaaaag gtattaccaa
      241 gttgcaatac cttttacgag gctcttttgt cttgttcttg tttcaattga ctatatatca
      301 cggatacagt tgggaaagaa gctattaaac atttggagag tccttttggg atgaacatgt
      361 caaatattac tatagatggg caagaaatgg atctgagtca aacgatgcct tcttatgctc
      421 aagtagtgag tctttatgat gatacaagta tctctgttag tagtaatgag acggacaaag
      481 tgttggctgg ctccctctat actgatacaa atgaacaggg attaacgatt ccaagcagtt
      541 tactaaaaaa ttggaatgaa cagacaggaa aaaatttgac agctaatgat cttattggca
      601 aatcagtctc agccagcatt gtagaaagtg ctgccgaaac tagtaagatt gctcaatttc
      661 aaacgaagat tgtacgtgta atcaatgatg aagatgacat ggaggacagc aacagtttca
      721 tgctgtctca tcaaatggaa acgattttga aagaggctgg atttacgaaa gctgtatctt
      781 attttatctt ggaactcaaa gatccatcac agacaaaagt agtaacagaa gaattacaga
      841 aaaataagaa gtatactgtg ctttctcaac agagagttct tgatattgtg attatcttta
      901 ttcgtgttat tcagggatta ttgattgtgc tttcatcaca agctattgtg gtagcagcgg
      961 ttatgattgg tatcattatt tacatcaata tcatgcagcg ttccaaggaa ataggtgtca
     1021 tgaaggcagt tggttatcag aatcgtgatg tcaaaggaat ttttatttac gaggctatct
     1081 ggattgtagg catcgccttg ctgctggcat ttttggttgc acaaggggtg ggaagtttgg
     1141 cgaatgcgat tgtaagtcac ttttacccat ccatcactaa agtttttgaa ttaaatcttt
     1201 tatctgtttt aggaactcta gttttcgctc tattacttgg ttatgtctca gcctacttcc
     1261 cggcgcgtaa gattagtaaa atggatcctg tagaaccgtt acgctatgaa tagtaaggga
     1321 ttccttgatt tacagtctta aaaagaaact aacatagaaa aacaatggac atacttgcaa
     1381 ttcaactcaa atagttgtat aataggtttg ttgaaaggtg atttgtagtg attcaagtta
     1441 ctcttttcac aataaaaatt tcatgatttt cataaggagg aaatcactaa tggtagttaa
     1501 agttggtatt aacggtttcg gacgtatcgg tcgtcttgct ttccgtcgta tccaaaacgt
     1561 agaaggtgtt gaagttacac gcatcaacga ccttacagat ccagttatgc ttgcacactt
     1621 gttgaaatac gacacaactc aaggtcgttt cgacggtact gttgaagtta aagaaggtgg
     1681 atttgaagtt aacggtaaat tcatcaaagt ttctgctgaa cgtgatccag aacaaatcga
     1741 ctgggctact gacggtgtag aaatcgttct tgaagctact ggtttctttg ctaagaaaga
     1801 agcagctgaa aaacacctta aaggtggagc taaaaaagtt gttatcactg ctcctggtgg
     1861 aaacgacgtt aaaacagttg tattcaatac taaccacgac gttcttgacg gtactgaaac
     1921 agttatctca ggtgcttcat gtactacaaa ctgcttggct ccaatggcta aagctcttca
     1981 agacaacttt ggtgttgttg aaggattgat gactactatc cacgcttaca ctggtgacca
     2041 aatgatcctt gacggaccac accgtggtgg tgaccttcgc cgtgctcgcg ctggtgctgc
     2101 aaacatcgtt cctaactcaa ctggtgctgc aaaagctatc ggtcttgtaa tcccagaatt
     2161 gaatggtaaa cttgatggat ctgcacaacg cgttccaact ccaactggat cagttactga
     2221 attggtagca gttcttgaaa agaacgttac tgttgatgaa gtgaacgcag ctatgaaagc
     2281 agcttcaaac gaatcatacg gttacacaga agatccaatc gtatcttcag atatcgtagg
     2341 tatgtcttac ggttcattgt ttgacgcaac tcaaactaaa gttcttgacg ttgacggtaa
     2401 acaattggtt aaagttgtat catggtacga caacgaaatg tcatacactg cacaacttgt
     2461 tcgtactctt gaatacttcg caaaaattgc taaataattc ttgagttgat agaaagcaag
     2521 gctttgtggt cttgcttttt atatggaaaa atggatgaca cgatcatcca ttctttttta
     2581 attctttttc aaatgtattt gaaagggtag tgaaagttag cttctctaaa gtaagtgggt
     2641 gggtaaagga aagtcggaag gcatgaagca taagccgact tgtctttgat ttactattat
     2701 agagagggtc gcccaggata ggaagattat gatgcgaaag gtgcacacga atctgatggg
     2761 ttcgccctgt ctttagcttg caacgagcca aggaagtctt gtttgagaat tgctttaatc
     2821 tgcttacata cgtttcagca tattgcccat tttttgcatc aactattctt tttctacgat
     2881 catggcgatc acgtccaatt ttgtctctga aaacaagttc ttttctgttg atatttccat
     2941 caactagagc ccaatattct ctagaaatct cttttttctc caataagcga ttgagaatgg
     3001 gcaggataaa aggatttttg gcaaagagaa ctaagccact ggtttccatg tccagacgat
     3061 gaacgacata gcaggtttgg ccaacatagg tactgacatg gttaagaagg gcaatttcgt
     3121 ttggttgatt accatgcgtt ttcatcccct ctggtttgtt tacaataatc aagtattgat
     3181 cttgataaac ttcctgcact aagtctgggt tgccccaagg gatcgtcttt tggggataat
     3241 cttcctcgtc aaaagtcaac tggcaaacat ctccaggatt tacgatttcg ttccagtgga
     3301 cttcttcttg atttatcaaa atatgtttct tgattctcaa aaaatgacgg atttttctag
     3361 ggatgaggag ttgttcctca agtaattgct ttaccgtcat ttgaggtaga gaggcgggta
     3421 atgtaaatgt gaattgcata cagatattgt aacaaaaaaa gccctatttg gataggaaat
     3481 agctaaattc ttgtcttcct atgatgaaga tgataaaata aacgcatgaa attagataaa
     3541 ttatttgaga aatttctttc tctttttaaa aaagaaacaa gtgaactaga ggactctgat
     3601 tctactatct tacgtcgctc tcgtagtgat cgaaaaaaat tagcccaagt aggtccgatt
     3661 cgaaaattct ggcgtcgtta tcatctaaca aagattatcc ttatactagg tttgagtgca
     3721 ggcttgctag ttggaatcta tttgtttgct gtagccaagt cgaccaatgt caatgatttg
     3781 caaaatgcct tgaaaactcg gactcttatt tttgaccgtg aagaaaaaga ggctggtgcc
     3841 ttgtctggtc aaaagggaac ctatgttgag ctgactgata tcagtaaaaa cttgcagaat
     3901 gctgttattg cgacagaaga ccgttctttc tataaaaatg acgggattaa ctatggccgt
     3961 ttcttcttgg ctattgtcac tgctggacgt tcaggtggtg gctctaccat tacccaacag
     4021 ctggctaaaa acgcctattt atcacaggat caaactgttg agagaaaagc gaaagaattt
     4081 ttccttgcct tagaattaag caaaaaatat agtaaggagc aaattctaac catgtacctt
     4141 aacaacgctt attttggaaa tggtgtgtgg ggtgtagaag atgcgagtaa gaaatacttt
     4201 ggagtttctg catcagaagt gagtctggat caagctgcga ctctggcagg gatgctcaag
     4261 gggccggaac tgtataatcc cttgaattcc gtagaagatt ctactaatcg gcgcgatact
     4321 gtcttgcaga atatggttgc agcaggatat attgataaaa accaagaaac cgaagctgct
     4381 gaagttgata tggcttcgca attgcacgat aagtatgaag gaaaaatctc agattaccgt
     4441 tacccctctt attttgatgc ggtggttaat gaagctgttt ccaagtataa tctaacagag
     4501 gaagagattg tcaataatgg ctaccgcatt tacacagagc tggaccaaaa ctaccaagca
     4561 aatatgcaga ttgtttatga aaacacatcg ctatttccga gggcagagga tggaacgttt
     4621 gctcaatcag gaagtgtagc tctcgaaccg aaaacagggg gagttcgtgg agttgtcggt
     4681 caagttgctg acaatgataa aactggattc cggaatttca actatgcaac ccaatcaaag
     4741 cgtagtcctg gttctacaat taagccttta gttgtttata cgccagcagt tgaagcaggc
     4801 tgggctttga ataagcagtt ggataaccat accatgcagt atgacagcta taaggttgat
     4861 aactatgcag ggatcaaaac gagtcgagaa gttcctatgt atcaagcctt ggcagaatcg
     4921 cttaatctac ctgctgttgc cgctgttaat gatttgggtg tcgacaaggc ttttgaggca
     4981 ggcgaaaaat tcggactcaa catggaaaag gtcgaccgtg ttcttggtgt cgccttggga
     5041 agcggtgttg aaaccaaccc tcttcaaatg gctcaagcat acgctgcctt tgcaaatgaa
     5101 ggtttaatgc ctgaagctca ttttattagt agaattgaaa atgctagtgg acaagttatt
     5161 gcgagtcata aaaattcaca aaaacgggtg attgataagt ctgtagctga caagatgacc
     5221 agtatgatgt tggggacttt caccaacggt accggtatta gttcatcgcc tgcagactat
     5281 attatggcag ggaaaactgg aacaactgaa gcagttttca atccggagta cacaagtgac
     5341 cagtgggtaa ttgcttatac tccggatgta gtgattagcc actggcttgg ctttcctacc
     5401 actgatgaaa atcactatct agctggctct acttcaaacg gtgcagctca tgtctttaga
     5461 aacattgcca ataccatttt accttatacg ccaggaagta cctttacggt tgaaaatgct
     5521 tataagcaaa atggaattgc accagccaat acaaaaagac aagtacaaac caatgataat
     5581 agccagacag atgataattt gtctgatatt cgagggcgtg cgcaaagtct agtagatgag
     5641 gctagccggg ctatctcaga tgcgaagatt aaggaaaagg ctcaaacaat atgggattcg
     5701 atagtcaatc tatttcgcta agatgcttgt caaagcctag ctttcttgtt ataatggata
     5761 ggatggaggc gttatggcac taaaaaaagc aagcctagct tgtgcggttt gtggttcgag
     5821 aaactattca atcaagatca gcggaaaccc caagcctaca cgactagaag taaataaatt
     5881 ttgtaagcat tgtggcaagt acactacaca cagagaaacg agataggaga gagcgatgcg
     5941 ttttattgga gatattttta gacttcttaa agacacaacg tggccaactc gcaaggaaag
     6001 ctggagagat tttcgttcta tcatggaata cacagctttc tttgtagtaa ttatttacat
     6061 ttttgaccag ttgattgttt caggtttgat tcgatttatt aacatttttt agaagattag
     6121 tggagttaat tacactagaa atcttctata ttatgaaagg aaatatcatg gatagttttg
     6181 ataaagggtg gtttgtttta caaacttatt ctggttatga aaataaggtg aaagaaaatc
     6241 tattacaacg tgcacaaacc tacaatatgt tggataatat tctacgcgtt gaaattccaa
     6301 cacaaacagt gcaagttgaa aaaaatggaa agagaaaaga agtagaagaa aatcgctttc
     6361 caggttatgt tcttgtagaa atggtcatga cagatgaagc ttggtttgtt gttcgaaaca
     6421 caccaaatgt tacaggattt gtcggatcac acgggaacag atcaaaacca actccattat
     6481 tggaacaaga aattcgtgac attttggtat ctatgggaca aactgttcaa gaatttgatt
     6541 tcgatgttga gattggtcaa actgtacgta ttattgatgg tgcttttgca gactacactg
     6601 gtaagattac agaaattgat aataacaaag tgaaaatgat tatctctatg tttggtaatg
     6661 acacagttgc agaagtaaac ctaaaccaaa tcgcagaatt ataaccctga gagaggctgg
     6721 agcctctctt ttttgtgcag tttaggagct aaagggaaca gaatggagaa aatgtaacaa
     6781 atgtgttttc taatctgtta gactgtatct agaaagggga aaattatgat taaagaattg
     6841 tatgaagaag tccaagggac tgt
//
LOCUS       DAVAZT010000082         6834 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVAZT010000082 DAVAZT010000000
VERSION     DAVAZT010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6834
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.082"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(201..1625)
                     /locus_tag="VQT45_001984"
     CDS             complement(201..1625)
                     /locus_tag="VQT45_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HET2360246.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMLKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2169..4448)
                     /gene="pulA"
                     /locus_tag="VQT45_001985"
     CDS             complement(2169..4448)
                     /gene="pulA"
                     /locus_tag="VQT45_001985"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HET2360247.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4560..6518)
                     /gene="ligA"
                     /locus_tag="VQT45_001986"
     CDS             complement(4560..6518)
                     /gene="ligA"
                     /locus_tag="VQT45_001986"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HET2360248.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6611..>6834)
                     /locus_tag="VQT45_001987"
     CDS             complement(6611..>6834)
                     /locus_tag="VQT45_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2360249.1"
                     /translation="FFTQVQTKVESEFLGRVLSTIFTLAILFMPIAKGFMTVLPSVHL
                     SSFLIIGSGVIILSCISFIYVRTHFEKLI"
BASE COUNT         2022 a         1502 c         1239 g         2071 t
ORIGIN      
        1 actatatata gtaaaatgaa ataataacag gacaaatcga tcaggacagt caaatcgatt
       61 tctaacaatg ttttagaagt aaatctgtac tattctagtt tcaatatact ataataccaa
      121 aaagttcgta ttttttctat aattattatt attttatagc aaaaaataaa accaggaaaa
      181 caatttcctg attttacacg ttatttcaca tcaaaaacaa tggatttgac atttgtcatc
      241 gcttcaatgc tatatttaat tccttgcact ccagctccag aacctttgac accaaggaat
      301 gggaaattat ctggaccacg ctgggtttta ttattaatgt ggactgtacc tacttcaagt
      361 ttttcagcaa tttcaaaggc ttttttgaaa tcatttgtaa agactgatga ttgaaggccg
      421 aattcagatt cgttggcaaa ggcaatagct tcctctacac tagccacacg aatgattggt
      481 aaaacaggac caaatggctc ttcccatgcc actttcatat cttttgtaac ttggtcaaaa
      541 agcactggcc agaggagatt gccctcacgt ttgattggtg taagagcctg agcctctttt
      601 tcttgtgcat cctcaatcaa gccccaaatg aagtcggctg aagcattgtc aataacaggt
      661 gtaatatcag cattgtcaaa tggatcacca actgttaatt tagaaacttc ttcctgaagc
      721 aaagtagcta atttatctgc tacactttcg agaacaatga cacgtttaat ggccgtgcaa
      781 cgttgtcctg agtagctaaa ggctcccgca acaatttgct tggcagcatg ttccaaatct
      841 gcatcttcta gtacaagagc tgcatctttc ccaccaagtt ccaacatgat aggacgcata
      901 ccagctaaac gaccaatacg ttctccaata ggagttgaac ctgtaaagtt gatgaagttg
      961 acttctttgt gctcaatgat ataatcccca atttctgaac cacgacctgt aatggtgttg
     1021 aaaacacctg ccggaatccc tgcttcttca aatgctttag ccaacaagag tccagaaatg
     1081 gaaccttgtg ttggtggctt caacatgacc acattccctg caatcaaggc aggtgcaatt
     1141 ttagaagcag ataaattaac tggataatta aagggagcaa tcgctagcac gataccaact
     1201 ggttcacgac ggacaacagc cagtttgttt ttacttgctg cctcaaaacc accaccttcc
     1261 attgcttgtc cagtgatacg gagaccttcc tcagcagcat aacgaatcaa gtctgctgta
     1321 cgcactactt ctccaattgc tgctttaatc ccttttgcta cttctttggc aaggatagta
     1381 ccaatttttt ccttatcgcg ttctaaaata gctgctgttt tatgcaaata agccgcacgt
     1441 tcaattgctg ataaagctcg ccatgctggc agggctgcac gcgcagcttg catagcctca
     1501 tcagcttcag tctgagtcat ggctggaact gtacccaatt cttcttgatt gattggtgaa
     1561 taaatcgtaa tttcttgttc agatgatttc cattttccat ttactaaatt ctgatatctt
     1621 gtcaaattct tgtcctcctg aaaatgatta agatatattt taccaaattt tcagaaaata
     1681 acaacccttt ttgcaaaatt tttgagatta ttttcacaag cttgattttt caaagtatac
     1741 tcaataaaaa taaaaaaatc cactacgtca aggcgaggct aatgtggttt gaagaaattt
     1801 tcgaagagcg tgaatgagta tcatctatag taaaataaaa aaactgaaca atttggttgg
     1861 ggacagccaa accaatttct cacaatgttt cagaaacaag ggtgtgctat tccaatttca
     1921 gcctactata actgtcatag attgctgaaa caaagtctag gtaaaagtct tcataataaa
     1981 aagacctcct atcaaatgtt caaaaacttt gataggaggt cttgtttcgt gaaaatattt
     2041 atcaaatttt ctatacaagt gagctgttag ccaggttctt tctattcttt caatttcaat
     2101 gaatggattt tttaccaata ctcataactg ggaatttttc tgtctaaaaa tagcgagata
     2161 gatggtattt ataaaacact caagacagct agactaatat catttaaaac attatcttct
     2221 tttgagcgac tgttggttac caacatagct aaatttcctg cattttcaaa ttgatagggt
     2281 tctgatttag cattcacaac taccaagagg tgttctttgc cgtgaacttc atagataagg
     2341 cagccgctat gttcaatcgc agaatgcaca aagacatgat ggtaaatttc atcatagcta
     2401 gagtaagaaa aggcaccagt ttttgtcttc aatcggatga cttgacggat aaactcaata
     2461 ctgtcttgac gctcattaat caagttccag ttcacttggt tcacactgtc aggagcatta
     2521 tagctattca tcgcacgctc tctatcatca tgggtcaact caccattttc accagtcgca
     2581 accagtttgg tacgaccaaa ttcttgaccg atttccataa aggccatccc ctgcatgagc
     2641 agattcatgg ctgtggcagt ttcgaccttg cgcatgattt gctctgaact ttggtctgga
     2701 tgaagggttg ccaataaatc gtgaagattg taattgtcat gggcttctac atagttaagc
     2761 acctgatttg gatgtgtata gcttcctaat tcacgacttc ctaggattgc tttagctaga
     2821 attggctctg tcgcagcacc actgacaaaa cctgacttga tagcaccata aacttctccc
     2881 cctttgacag catcgcgctg attgtcatta aagaaaccaa tatttggcat ctggtaggca
     2941 ttgtccttct tggccttatc ataaggggca agacctgttc ccatatccca tccttctcca
     3001 tagaggataa tgttggagtc aatttcatcc aagctttgac gaatcatctg catggtcttg
     3061 acatcatgaa tccccatcaa gtcaaaacgg aagccgtcaa tattatattc ctgcacccag
     3121 tatagaagag aatcaatcat atacttgcga aacatttcgt gttcactggc tgtttcattt
     3181 ccaacacccg ttccattctg gaaggtacca tctggattca tacgataata gtaatcaggg
     3241 actgttgttt ggaatggtgc atcaacaact gagaaggtat ggttatagac tacatccata
     3301 atgactccaa tacccgcatc gtgataagct tgaaccatca ccttcaaatc acgaatgacc
     3361 tgagctggat catctggatt agttgaaaaa ctagtttctg gcgcgttata gttttgtgga
     3421 tcataacccc agttgtaggt tacatttcca tcctcatcgt attctttatg acggtctgca
     3481 attggttgca attgaacata attgtagccc agcttcttga tgtaatcaaa agcagttgac
     3541 tggccgtatt ggttaactgt tccagcctga gcagcaccca agaaagttcc tcgaagatgt
     3601 tcatctacac ccgatgtagg tgatttagtc aaatcacgaa tatgcatttc acagataact
     3661 gccttacatg gattttccaa gcgccaagta gcctccgaac cgtgcttaac ctcgaagttt
     3721 tcaacttgct tttctacatg gctcagaata gctgaacgtt tgccatcagg gctggtcgcg
     3781 attgtataag gatcacgtgt cagtgtttgg tgatgaggga attggacttg atactgataa
     3841 gtcttaccta ccaaatcttc ttcaacatcc aaactccaga caccgattgt attgtcctta
     3901 tgattataag agtagctatt gcctcttttc atctcaaaag tcttccaaac gggtgcatca
     3961 ttagcagctg attcataaac gacaacttgc acttctgtcg ctgtaggtga ccagagggaa
     4021 aaatgagcct gattgtcctc tacacggcaa cccaattctc cttggtaacc ccaatgatga
     4081 tcaaaactag cactgttaat ggccttatca aaggcaaaag gattttgatt tttatagaaa
     4141 ggactggcaa tagcaggatt ttcagagtaa taaatcctat catcgccttc caaaatccag
     4201 acctctgtta ataggggata gtgattaaaa cggatagaat attctttact agtttgacct
     4261 gtatgaacca caaaattcaa gctttctata acatgtgaac ttgggtgttc aaagctaaat
     4321 aaagctccaa aataatcttc tttgtaggtt agcaaatcaa ttcgttgatc ctgacttttt
     4381 acaaaggagc aagtgtcata ttctccattc ttacgatggt aatgaatgcg catagggtag
     4441 ttatacattt tttatttttc ctttttactt tgtttctatt tcactaataa atttttgtca
     4501 atctcgtctc aattaacaga catagtcata ttctctaaac tctgttttta aacgatccat
     4561 tacaaacttt ctagccatgc ctcatctctg acctggatac caagttcttg tgctttttgc
     4621 agtttacttc cagcgtctgc acctaccacg acgaggtcgg tctttttaga aacactacct
     4681 gtcactttgg cacccagact ttcgagttta cttttagctt ctgagcgctt gagtcgttcc
     4741 aattttcctg tcaataccac ggtcaaacct gacaaggccg catccgctac taccgtctgt
     4801 cctttatagt ccagattgac cccagtttct ttcaattctc tgagcagaat ttcagagcct
     4861 tctgtcgcaa aataagtctg aagacttttg gcaatcacgc cacctagact ttcaatacta
     4921 gccacttcct ctgaatctgc ctgagacaga ttttcaattg aatggaaata ttgaagtaaa
     4981 agctgactag ccttgcttcc gacatgacga attcccaaac caaataagag cttctcggca
     5041 gaattttcct ttgatgcttg gatagcctga tacagtttag cagcggactt ttccttaacc
     5101 ccctctaaaa ggaggaaatc ctcttcttgc aaacgataaa tatccgccac atccttgact
     5161 aaattagcag caaaaagctt ctcaacaata gatggaccaa ggcctgtaat attcatagca
     5221 tcacgagaag caaagtgaat caagccttcc atgatttgag cagggcaacg cggattgata
     5281 caacgtaggg ccacttcatc ttcaaagtgc aacaagtcag agttacaact tggacagttt
     5341 gtagggatat ctagtttttc ttcagaaacc cgtttggact ctaccacacg taaaacggca
     5401 gggatgatgt caccagcctt atatacaatg accgtatcgt cttttcggat atctttttca
     5461 gcaatataat ctacattgtg cagggtcgca cggctaacag tcgtaccggc aagttgtact
     5521 ggtgttagat tagcagttgg agttacaaca ccggtacggc caactgtcca gtcaactgat
     5581 aagagttgag cttctttttc ttcagcaggg aacttgtagg ctactgccca ctttggagcc
     5641 ttaacggtaa aaccaagttc ttcttgactt gctaggtcgt tgaccttgat taccactcca
     5701 tcaatatcgt aaggcagatt ttcccgttcc tgtcctactt cttggataaa attccagatt
     5761 tcatctatgt tttcagccaa gattcgctta ggattgacca caaaacctag ttgttctagg
     5821 tacttcaaac ccttttcttg gctatcacga gttgaagggc tggcttcttg atagagaaac
     5881 gttgcaagat tacgcttggc aactactgct gtatccaact gacgcagagt tcctgctgcc
     5941 gcattacgag gattagcaaa ttcaggctct ccattttctt ggcgcacttg gttaacttgg
     6001 tcaaaggaag cgcgtggcat gtaacattcc ccacgaactg tgatatctag ttcttctggc
     6061 aaagtcaaag ggatgtcctt aacacgcttg aggttttctg tgatattttc accaattgaa
     6121 ccatctccac gtgttacccc agcaaccaaa atcccctttt cataagtcag cgagatagat
     6181 aagccatcga ttttcagctc acaaatatag gtcggatgag ccacttcctt acgaacacgc
     6241 gcatcaaaag catctagctc ctcacgtgaa aaagcatcct gcaaactata aagaggatac
     6301 tgatgactgt atttttcaaa accatctaaa accttgccac caacacgatg agtcggactg
     6361 tctgctagca cttgctctgg ataagcagtt tctaactcga ccaactcacg gtaaaggcgg
     6421 tcatactcac tgtctgaaac cgagggatta tcgctggtat agtactcagt cgcatagcga
     6481 ttgagcaaag cgactaactc attcattctt ttattcataa gaccatttta ccataaaaca
     6541 agccctcctc acaaacgaga agggcggaaa aaacacttag tttgaaatta tttttgaaac
     6601 tcaagcaacc ttatatcaat ttttcaaaat gagttcgaac ataaataaac gatatacaag
     6661 acaagatgat aacaccactt ccaattatca ggaaagaaga gagatgtaca cttggcaaga
     6721 ctgtcataaa tccttttgca ataggcataa atagaatagc taaggtaaaa attgtactca
     6781 gtactcttcc aagaaattcg ctctcaacct tggtttgtac ttgagtaaaa aagt
//
LOCUS       DAVAZT010000083         6688 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVAZT010000083 DAVAZT010000000
VERSION     DAVAZT010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6688
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.083"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(84..1244)
                     /locus_tag="VQT45_001988"
     CDS             complement(84..1244)
                     /locus_tag="VQT45_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2360250.1"
                     /translation="MKKKFALSFVALASVALLAACVEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTNMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            complement(1345..1593)
                     /locus_tag="VQT45_001989"
     CDS             complement(1345..1593)
                     /locus_tag="VQT45_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HET2360251.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            complement(1672..2262)
                     /gene="clpP"
                     /locus_tag="VQT45_001990"
     CDS             complement(1672..2262)
                     /gene="clpP"
                     /locus_tag="VQT45_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HET2360252.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            complement(2436..3065)
                     /gene="upp"
                     /locus_tag="VQT45_001991"
     CDS             complement(2436..3065)
                     /gene="upp"
                     /locus_tag="VQT45_001991"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HET2360253.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETFQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(3154..3621)
                     /locus_tag="VQT45_001992"
     CDS             complement(3154..3621)
                     /locus_tag="VQT45_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HET2360254.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            complement(3640..4197)
                     /locus_tag="VQT45_001993"
     CDS             complement(3640..4197)
                     /locus_tag="VQT45_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET2360255.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            4322..5167
                     /locus_tag="VQT45_001994"
     CDS             4322..5167
                     /locus_tag="VQT45_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET2360256.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEDGGLLM
                     GYEID"
     gene            5226..6398
                     /locus_tag="VQT45_001995"
     CDS             5226..6398
                     /locus_tag="VQT45_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET2360257.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSNPI"
     gene            6413..6658
                     /locus_tag="VQT45_001996"
     CDS             6413..6658
                     /locus_tag="VQT45_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HET2360258.1"
                     /translation="MEQSPKKKKGTTLEHIILLRGVTPNGKNAIPKMSYLVDILTEAD
                     FQQVRTYIQSGNIILESNLALEEIREQVHTLLDFLQN"
BASE COUNT         1912 a         1396 c         1294 g         2086 t
ORIGIN      
        1 agtttgaaga gattttcgaa gagtattaaa tatcgaaaca gggagtgagt caaaggctca
       61 ttccctattt caacattttt ctattatggt tttacaactt ctgctgcttc aactttacca
      121 ttgttcatgg tcatcatgta agcagttttg actgtgttgt ggtctgcatc gaagcttgtt
      181 tgaccagtta caccttcaaa atcttttgtt ttagcaaggt tatccttgat ttcacctgaa
      241 tttttagcac cttttgctgc gtttgctaca aggtgaactg aatcataagc caaggctgca
      301 aatgttgaag gctcttcatt gtacttagca cggtaagcgt caaggaaggc tttagcttta
      361 gctgaaactt ctacagtagt tgagaagcct gagataaagt agatgtttga tgctttttca
      421 gcagttgctt gttgtacaaa ctcctcaccg ttgaatccat caccaccaac gattggtttg
      481 tcaattccca tgccacgcgc ttggtttaca atcttaccag cctcattata gtaaccagga
      541 acaacgatag catcaaagtc tttccctttc atgtttgtaa gggctgcttg gaagtctgtg
      601 tcacctgcta cgaaagtttc atctgcaacg atttcaccct tgtatgactc gcggaaagat
      661 ttagcaatcc ctttagcata gtcactggca ttgtcagtgt aaagaacaac tttcttagca
      721 tttaattttt cagaaacata gtttgagata atttttcctt ggaagctatc ttggaaagtt
      781 ccaataaaga ggtaatcttg acctttagtc aatccatctt gagtcgcact tggtgagatc
      841 aatggaacac ctgcttttgt agcgttcgct accgcagctg cagtcgcacc agatgtcgca
      901 ggtcctacga ctgctgatac tttagattgg gttacaaggt tagttgtaac tgaagcagcc
      961 tcagctgttt cagacttatt atctttatcg actacttcga tttgttttcc atcgatacca
     1021 cctgcggcat tgatttcatc aacagccaat tgggcacctt tttgttcagc tgttccgtat
     1081 gcagctaaag aacctgattc ttcaaagtta aacccgattt taattgtctt ttcctctact
     1141 gagttaccag cagtgttgac tgctccagac ttcacttcta cacaggctgc aagaagtgct
     1201 acacttgcaa gcgccacaaa cgatagggca aattttttct tcatcttttt gtctccttat
     1261 ttcttaaata gtctgttaag aatataccga attatcagaa aattgtcaat gttttccttg
     1321 aactttttcg atgataacgt tttcctatcg ataaagattg cccacaaagg gtgtttccaa
     1381 ctcttggata tgacaaaccc taactttttt aataaatttt tccttgctca agcgtccgac
     1441 caattgctcc acttcttgag ttggaacata gagttgtaag taacgatgtt tcttggaatg
     1501 ataggtaata tctccataat cctgcagttt tttggcatca cgattatagt aaagatagat
     1561 aatcaagcca gagcgattga ctttttcaaa catgataaat cctctttcta agaaatctct
     1621 ccctattata ccaaaaaaag caaacccagt cgagtttgcc ttctatcatc attagttcaa
     1681 tgaattgttg gccataattt catcaataaa gccatattca agtgtttcct gggcgctcat
     1741 ccagttatca cgttctgcat ctgcatggac tttttccatt gactgacctg aattttcagc
     1801 caagattttt tccaaggtat tacgagtttt gagcaagtgt tctgcagcga tagccatatc
     1861 agtttgttgg gtaccaccac ctgtaccgcc cattggttgg tgaatcatgt attcagcatt
     1921 tggaagcatg aaacgtttgc cttttgctcc acttgatgcg atgactgttc ccatagatgc
     1981 agccattccc ataacaatgg tttggacatc tgccttgata aagttcatgg tatctacgat
     2041 tgccaaacca gctgaaacag aaccacctgg tgtattgaca taaaggtaaa tatcttttgt
     2101 actatcttgg gcatccaaga aaagcagttg ggcaataaca gagttagcca tattgtcttc
     2161 aaccggacct gtcagcataa tgatgcggtc tttgagaaga cgtgagtaaa tatcgtaaga
     2221 acgttctcca cggcttgttt gttcaataac tacaggaatc attcatttct ccttttgagt
     2281 tttaattttg ttggtcaaat gactgaagat aagactatta taatatcttg gtcaaaaaag
     2341 gtcaaatttt tgctctgctt tcattagaca gaaacaaaaa cccaacctcc tttcgtgact
     2401 ggaaatactt ttccaagtca ttcttctttt cgatcttatt ttgtaccgaa caagcggtct
     2461 ccagcatctc caagacctgg aacgatataa ccgtgttcgt tcaaacgttc atccaaggct
     2521 gctgtaaaga tttctacatc tggatgagct tcttgaaggg cttttacacc ctctggagca
     2581 gatacaaggc agacaaattt gatatttgat gcgccacgtt ttttaagaga atcaacagcc
     2641 aagattgctg agccacctgt tgccaacatt gggtctacta caaaaatttg acgttggtca
     2701 atgtcctcag gcaatttcac caagtattca actggttgaa atgtttcttc atcacggtac
     2761 ataccgatgt ggccaacttt agcagctgga accaagctca agagaccatc aaccatcccg
     2821 atacctgcac gcaagattgg gacgatggcc aatttcttac ctgccaattg tttttgaact
     2881 gtttttgtaa ttggtgtttc gatttccaca tcttctagtg gaagatcacg aagtacttca
     2941 taccccatca acattgcaat ctcatctact agctcacgaa aagcttttgt agaagtatct
     3001 gtacgacgca agattgacaa tttgtgttga atcagtgggt gattaataac ttcaattttt
     3061 cccatttttg gaattccttc tttcaattta ttcttcttat tataccaaaa aacgggttaa
     3121 aaatctttct aaaccattta tttttgataa tttttacatt agatcagcct ctttaagagc
     3181 tgtctgtact gtctcaagtg gtaaatgggt caattctgtc cctttttctt gataaaggta
     3241 ttgggcgtag tcgtccattc ggtactggtt gatataaacc acacgcttgc agccgacctg
     3301 aagcaattgt tttgtacagt tgagacaagg aaaatgggtt acataggctg taaagccttt
     3361 gggaacacca cgctcagcac cttgaaggat agcattgacc tcagcgtgaa gggtgcgaac
     3421 acagtggcct tcaatgacca aacattcgtg atcaatacaa tgctcagtcc ctgacaccga
     3481 accattgtaa ccagtggaaa taaccttatt atcttttacc agaatcgcgc ccactttagc
     3541 acgtttacaa gtggaacgat tcgcaattag tagagcttgg gctgcaaaat actcatccca
     3601 ggccagtctt ttttcagtca tctcttttct cctttttctc tattttttaa aaaatggtaa
     3661 acctaaatct gcaatctttt cagctggtac cttcatgcca tccttgatcc attttagaag
     3721 gacagagacg atggctgagc tccagaagga atgaagataa gagctgacac cttttgattt
     3781 cccatggtat ttttctagaa attcctgcat ggcttggaca aagatttttt ccagatggta
     3841 atccaaggcc aattgaatta ctctagcttc ctttctggcc tcccggaaaa ggtgaaccca
     3901 aaccaaataa aggtctgtct ttaaatcgta atgatgcagc tgttccataa tattgtggac
     3961 agttcgttta aagacgctct ctaaaatttc ctctttggag tcataattgc gataaaaggc
     4021 cgcacgcgaa acacctgcac gtttgaccaa ttcagaaata ctaatcttgg tcagttcctt
     4081 tttttccaag agttgcaaga gggctgtttc aatggcttct ctggttaata aattggattc
     4141 ttggtttgat tttctgagat tttcaagaga cttttcagag attctacgtt cagacataac
     4201 attttctttc tacttgtcac aacagacgga tgatgctttt gtttcaaggg ttttcatgat
     4261 ataattgtaa aaaaagacag aacctttgtc aatgtataac tgacaaagat ggagaatttc
     4321 tatgacttgg aagattattg ctgactctgg ttgtgattat cgtcaactgc caacaccagc
     4381 tattaacaca acctttgtaa gtgtcccctt aaccattcaa gtagctgatc aggtctttgt
     4441 tgatgacgcc agtctcgata ttgaccaaat gatggaaacc atgtatgcaa ctgcagaagc
     4501 ttcaaaatcg gcttgtccaa gcccagatga ctatttgcga gcatttgaag gtgccaaaaa
     4561 cattttccta gtaaccatca caggtaccct ttctggcagt cacaatagtg ctcaactagc
     4621 aaagaatatt tatctggaag accatcctga cactaagatt catgtgattg atagtttatc
     4681 tgctggtggt gaagttgacc tactcgtaga aaaattgaat gacttgattg accagggctt
     4741 gtcttttgaa gaagtggttg aagctatcac cgcctatcaa gaaaaaacta agttgctctt
     4801 tgtcctagcc aaagtcgata acttggtgaa gaacggccgt ttgagcaagc ttatcggtac
     4861 ggtcgttggc cttctcaaca ttcgtatggt cggaaaagct agtgaaactg gaactctcga
     4921 attgctacaa aaagcaaggg gatcaaagaa atcagttcaa gctgcctatg atgagttagt
     4981 aaaagctgga tatgctggtg gccgtattgt catggcccaa cgcaataacg aaaaatgttg
     5041 tcaacagctc tcagagcgaa tccgtgaaac cttcccacaa gcggatatta aaattctacc
     5101 aacctctggt ctctgcagtt tctatgcaga agatggcggt ttgctgatgg gctatgaaat
     5161 tgattaattg tattcttgac aagaggtgac catcatctct tgtttttttg tggtacaata
     5221 gagctatgaa acattttgat actattgtca tcggtggggg acctgctggt atgatggcta
     5281 cgatttccag tagcttttat ggacagaaaa ccctcctcat cgaaaaaaat cggaaacttg
     5341 gaaaaaaatt agctgggact ggtgggggac gttgcaatgt gaccaacaat ggtagcttag
     5401 acaacctgct agctggaatt cctggaaacg gacgctttct ttacagtgtt ttctcccagt
     5461 tcgataatca tgacatcatc aactttttta cagaaaatgg tgttaaactt aaggtcgaag
     5521 accacggacg cgtctttcca gccagtgaca agtctcggac tattatcgaa gctttggaaa
     5581 agaaaatcac cgaactaggt ggtcaagttg ctactcaaat agaaatcgtt tctgttaaaa
     5641 aagtagatga ccagtttgtc cttaagtcag cggatcaaac cttcacttgt gagaaactca
     5701 ttgtcacaac aggtggtaag tcttatcctt cgactggttc gactggtttt ggtcacgaga
     5761 ttgctcgcca ttttaagcat accatcaccg atcttgaggc tgctgaaagt cctttattaa
     5821 cagattttcc acataaagcc ttacaaggga tttctttgga cgatgtgacc ctaagttatg
     5881 gtaagcatgt catcactcat gatttactct ttacccactt tggtttgtca ggtcctgctg
     5941 ccctacgcat gtctagcttt gtcaaaggtg gggaggttct ctcactcgat gttttgcctc
     6001 aactttctga gaaggacttg gttacatttc tagaagaaaa tcgggaaaaa tccttgaaaa
     6061 acgctttaaa aaccttgtta ccagaacgct tggccgaatt ttttgtacaa ggatatcctg
     6121 aaaaagtcaa acaactgact gaaaaggaac gagaacaact tgtccagtcc attaaagaac
     6181 ttaaaattcc tgtaactgga aaaatgtccc ttgcaaagtc ctttgttacc aagggtggag
     6241 tcagtctcaa ggaaatcaat cctaaaaccc ttgaaagtaa gctggtacct ggcctccact
     6301 ttgcaggcga agttatggat atcaatgccc acacaggtgg ctttaacatc acttctgccc
     6361 tctgtaccgg ctgggtggcg ggatcaaatc caatctaaat atacattact aaatggaaca
     6421 atcccccaaa aaaaagaaag gaactacttt ggaacatatt atcttgctaa ggggagtcac
     6481 tcctaatgga aaaaatgcta tccctaaaat gtcttatcta gtagatatct tgacagaagc
     6541 tgattttcaa caagttcgaa cttatattca aagtggaaat attattcttg aaagtaactt
     6601 agctctcgaa gaaatacgag aacaggttca tactctatta gacttcctgc aaaactagaa
     6661 tcctagttca tgattgataa taccagca
//
LOCUS       DAVAZT010000084         6447 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVAZT010000084 DAVAZT010000000
VERSION     DAVAZT010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6447
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.084"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            222..422
                     /locus_tag="VQT45_001997"
     CDS             222..422
                     /locus_tag="VQT45_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360259.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            447..863
                     /locus_tag="VQT45_001998"
     CDS             447..863
                     /locus_tag="VQT45_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360260.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1094..1801
                     /gene="ccdA2"
                     /locus_tag="VQT45_001999"
     CDS             1094..1801
                     /gene="ccdA2"
                     /locus_tag="VQT45_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET2360261.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1812..2369
                     /gene="sdbB"
                     /locus_tag="VQT45_002000"
     CDS             1812..2369
                     /gene="sdbB"
                     /locus_tag="VQT45_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HET2360262.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2490..3881
                     /locus_tag="VQT45_002001"
     CDS             2490..3881
                     /locus_tag="VQT45_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HET2360263.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPSWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4024..4941
                     /gene="adcAII"
                     /locus_tag="VQT45_002002"
     CDS             4024..4941
                     /gene="adcAII"
                     /locus_tag="VQT45_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HET2360264.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            4949..>6447
                     /locus_tag="VQT45_002003"
     CDS             4949..>6447
                     /locus_tag="VQT45_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2360265.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLVFDPAQITYRTVNGVAVPHGDHYHFIPYSQLSPLEEKLA
                     RMIAVKGQNGAVLPGMHYLKPAPKPQVQPSTEKKQTDFAVEQVVRKVGEGYVVEIAGV
                     SHYVFAKDLAKDKIDAIENLLSKKTQETHALVAKKENVAPRDQEFYDKAYNLLTQAHK
                     VLSENKGRTSDFQALDKLAERLNNESSNKVKLVDDLLAFLAPITHPERLG"
BASE COUNT         1980 a         1172 c         1354 g         1941 t
ORIGIN      
        1 atggtttcag aaatttctct taccaacatt aaccacacca tcggttatta tagtaaaatg
       61 gaataagaac aggacaaatc gatcaggaca gtaaaatcga attctaacaa tgttttagaa
      121 gtctatatgt actattctag tttcaatata ccataactgc tcctagtcaa cctgcaagtc
      181 ctgtcccagc tccaagctca gctccgactc aagatcctag agtggtagca agcgcttcgg
      241 ctagctcaac gagcacacaa gctcaagagc aagttgacaa gtctgaactt cgtgccttga
      301 gtcaagagtt agaccaacgc ttgaaagctt tggcaacagt atctgatcca aaaatcgatg
      361 caaccaaggc tgtcctccta gatgctcaaa aagctccgga agatagtgcc ttgacagagt
      421 aaggtctgca tactgcagta gagtctgtga aggctgcctt ggactctctc aaagatgtga
      481 aagcaaatgc tagcgacagc aagcctgcac aggacaagaa ggatgcaaaa caaggaacgg
      541 aagatagtaa ggattcagat aagatgactg aaacaaactc agttccggca ggagtgattg
      601 tggtcagtct acttgccctc ctaggcgtga ttgccttctg gctgattcgc cgtaagaaag
      661 agtcagaaat ccagcaatta agcacggaat tgatcaaggt tctaggacag ctagatgcag
      721 aaaaagcgga taaaaaagtc cttgccaaag cccaaaacct tctccaagaa acccttgatt
      781 tcgtgaaaga agaaaatggc tcagcagaga cagaaactaa actagtagag gagcttaaag
      841 caatccttga caaactcaag taaaacatga tttatgaaat gtcagaccta aaagacattt
      901 tcgttcacaa aagcagtgac gagtaatcct tgtcgttgct ttttggctat tttgggggat
      961 aagatccgcc ttgactagca aaagaaaaga ttggtccaat agtgcccgat acgattttgc
     1021 gtagcagaaa gcttacaaat aaaattgaat atagtaaaat aggattagaa ttattaagaa
     1081 agttggttct ttattggaaa cgatagtatt tttaatctct gtttttctag caggtgtttt
     1141 atcctttttt tctccttgta tttttcctct tctgccagtc tatgctggga ttttattgga
     1201 tgatcaagaa agtgcaaaaa gcttttcttt gtttgggaga aaggttctct ggtcaggctt
     1261 gattcgaaca ctttgcttta tcgctggtat ctctctcatt ttctttattc taggctttgg
     1321 tgctggttac tttggtcata ttctctatgc aaattggttt cgatatgtca tgggagctat
     1381 tattatcatt ttgggtcttc accagatgga aatttttcat ttgaagaaat tagaagttca
     1441 aaaaagtttt acctttaaaa aatcagattc taatcgttat tggtcagctt ttttacttgg
     1501 tattaccttt agctttggtt ggacaccttg tattggtcca gttttaagtt ctgttttagc
     1561 acttgcggct tctggaggca atggtgcttg gcaaggagcg atttatactc tcatttacac
     1621 tctgggcatg gcccttcctt tcttggtctt ggcactagct tcaggtctag tcatgccata
     1681 ttttagtaaa atcaagcgtc atatgatgct actaaagaaa attggtggtt tcctcattgt
     1741 tttaatggga attttgttac tattaggaca agtaaatgtt ctagctggaa tttttgaata
     1801 aaggaggaca aatgaaaaaa gtaatgtttg ctggcttaag tctcttgtca ttagttgtat
     1861 tgatggcctg tggtgaggaa gaaactaaaa agactcaagc agcacaacag ccaaaacaac
     1921 aaacgactgt acaacaaatt gctgttggaa aagatgctcc agacttcaca ttgcaatcca
     1981 tggatggcaa agaagttaag ttatctgatt ttaagggtaa aaaggtttac ttgaagtttt
     2041 gggcttcatg gtgtggtcca tgcaagaaaa gtatgccaga gttgatggaa ctagcggcga
     2101 aaccagatcg tgatttcgaa attcttactg tcattgcacc aggaattcaa ggtgaaaaaa
     2161 ctgttgagca attcccacaa tggttccagg aacaaggata taaggatatc ccagttcttt
     2221 atgataccaa agcaaccacc ttccaagctt atcaaattcg aagcattcct acagaatatt
     2281 taattgatag ccaaggaaag attggaaaga ttcaatttgg tgctatcagt aatgcggatg
     2341 cagaagcagc atttaaagaa atgaactaga atcgataaaa tctgattaca agatgtagtc
     2401 agattttttt agaaaaacat tttataaata ttcacatatc tcctatattt atggtaaaat
     2461 agaattatca gtttattttg gagtcaaaga tgaatatatt tagaacaaag aatgttagtt
     2521 tagataaaac agagatgcat aggcatttga agttatggga tttgattttg ctgggtatcg
     2581 gagccatggt agggacaggc gtctttacaa tcacaggtac tgcagctgca acacttgctg
     2641 gcccagccct agtgatttca atcgttattt ctgccttgtg tgtgggatta tcagccctct
     2701 tttttgcaga atttgcctcg cgagtacccg ctacaggagg tgcctatagt tacctctatg
     2761 ctatcttagg agaattccct tcctggttgg ctggttggtt aaccatgatg gagttcatga
     2821 cagccatatc aggcgtagct tcgggttggg cagcttattt taaaggcttg ctctctcaat
     2881 acgggatagc ctttcctcag gctttaaatg gtacctttaa tcctcaagca gggacatttg
     2941 ttgatttatt gcctattctt gtcttggtct tggtgacttc gcttgtttta ctaaatgcca
     3001 aggcagcctt acgctttaat tcgattctag ttattttgaa attttccgct ttagctctct
     3061 ttgttttagt aggaatttgg aatattaagt ttgataattg gagcaatttt gctccttacg
     3121 gttttggaca aatctatgga gctagcactg gtattatggc tggtgcgtcc ttgatgttct
     3181 tcggtttttt gggatttgaa tccatctcta tggctgtaga tgaagtcaag actcctcaaa
     3241 aaaatattcc tagagggatt gtcttatcgc tttctatcgt aaccattctc tatgccttgg
     3301 tgacccttgt tttgactggt gtggttcact atagtcattt aaatgtcgat gatgccgttg
     3361 cctttgccct tcgtagtgtt gggattagtt gggcagccaa ctatgtgtca ttagtggcta
     3421 tcttgacctt gattacagtt tgtatttcga tgacctatgc cctatcgcgt atgatttaca
     3481 gtttagcacg tgacggctta gtgcctgctg cctttaagga actgacgaag actagcaaga
     3541 taccaaagaa tgctactatc ttgacaggtc tagcttcagc agtagcagca ggaatgttcc
     3601 cactagccag tattgcagcc tttttaaata tttgtacctt agcctacttg atcatgctgg
     3661 cttatggtct gattcgctta cggaaagaaa aaggaatgcc caaagctggg gaatttaaaa
     3721 caccattggt acctctgtta ccaattttat cgatcatcat ttgtttatcc ttcatgttac
     3781 agtataatat gaacacctgg attgctttcc tagttgcgtt gttagtagga agtattattt
     3841 acttcactta tggctataag cattctacca tagaagaata aagtgaaagt ctattgagtt
     3901 gttgacactc agtagatttt tatatgtgaa agaaatttca aattttttct aaaaatatct
     3961 tgacagatta aattttcagg agtagaatat ttactagtta attaaatggt taaggagttg
     4021 ttcatgaaga aacaaaattt atttttagtc ctgttaagtg tctttctttt gtgtttgggg
     4081 gcttgtggtc aaaaggaaag tcagacagga aaggggatga aaattgtgac cagtttttat
     4141 cctatctacg ctatggttaa ggaagtatct ggtgacttga atgatgttcg gatgattcag
     4201 tcaagtagtg ggattcactc ctttgaacct tcggcaaatg atatcgcagc catctatgat
     4261 gcagatgtct ttgtttacca ttctcataca ctcgaatctt gggcaggaag tctggatcca
     4321 aatctaaaaa aatccaaagt gaaggtctta gaggcttctg agggaatgac cttggaacgt
     4381 gtccctggac tagaggatgt ggaagcaggg gatggagttg atgaaaaaac gctctatgac
     4441 cctcacacat ggctagatcc tgaaaaagct ggagaagaag cccaaattat cgctgataaa
     4501 ctttcagagg tggatagtga gcataaagag acttatcaaa aaaatgcgca agcctttatc
     4561 aaaaaagctc aggaattgac taagaaattc caaccaaaat ttgaaaaagc gactcagaaa
     4621 acatttgtaa cacaacatac agccttttct tatctagcga agagatttgg gcttaatcaa
     4681 cttggtattg caggtatctc tcctgaacaa gaaccaagtc cacgacaact aacagaaatt
     4741 caggaatttg ttaagaccta taaggttaaa acgattttta cagaaagtaa cgcttcttca
     4801 aaagtagctg aaactcttgt caaatcaaca ggtgtgggtc ttaaaactct gaatccttta
     4861 gagtcagacc cacaaaatga caagacctat ttagaaaatc ttgaagaaaa tatgagtatt
     4921 ctagcagaag aattaaagtg aggaaagaat gaaaatcaat aaaaaatatc tagcaggttc
     4981 agtggcagtc cttgccctaa gtgtttgttc ctatgaactt ggtcgtcacc aagctggtca
     5041 ggttaagaaa gagtctaatc gagtttctta tatagatggt gatcaggctg gtcaaaaggc
     5101 agaaaatttg acaccagatg aagtcagtaa gagagagggg atcaacgccg aacaaattgt
     5161 tatcaagatt acggatcaag gttatgtgac ctctcatgga gaccattatc attactataa
     5221 tggcaaggtt ccttatgatg ccatcatcag tgaagaactt ctcatgaaag atccgaatta
     5281 tcagttgaag gattcagaca ttgtcaatga aatcaagggt ggctatgtga ttaaggtaga
     5341 cggaaaatac tatgtttacc ttaaagatgc agcccatgcg gacaatattc ggacaaaaga
     5401 agagattaaa cgtcagaagc aggaacgcag tcataatcac aactcaagag cagataatgc
     5461 tgttgctgca gccagagccc aaggacgtta tacaacggat gatgggtata tcttcaatgc
     5521 atctgatatc attgaggaca cgggtgatgc ttatattgtc cctcacggca atcacttcca
     5581 ctatattcct aagagtgatt tgtctgccag tgaattagct gctgcccaag cctattggaa
     5641 tgggaagcag ggatctcgtc cttcttcaag ttctagtcat aatgcaaatc cagctcaacc
     5701 aagattgtca gagaaccaca atctgactgt cactccaact tatcatcaaa atcaagggga
     5761 aaacatttca agccttttac gtgaattgta tgctaaaccc ttatcagaac gccatgtaga
     5821 atctgatggc ctagtatttg atccggcaca aataacatat cgtacagtca atggtgttgc
     5881 tgtaccgcac ggagaccatt atcactttat tccttattca caactgtcac ctttggaaga
     5941 aaaattggct cgtatgattg ctgttaaggg acaaaatggt gcagtcttgc caggaatgca
     6001 ttatttgaaa ccagcaccaa aaccgcaagt tcaaccatca actgagaaaa aacaaactga
     6061 ttttgcagta gaacaggttg ttagaaaagt tggagaaggc tatgttgtgg aaattgctgg
     6121 tgtcagtcac tatgtttttg ctaaagactt ggctaaggat aagattgatg ctattgaaaa
     6181 tctcttgtct aagaaaactc aagagacaca tgctctagtt gctaaaaaag aaaatgtcgc
     6241 tcctcgtgac caagaatttt atgataaagc ttacaatctg ttaacccagg ctcataaagt
     6301 cttgtctgaa aataaaggtc gtacttctga tttccaagcc ttagacaaat tagcagaacg
     6361 cttgaataat gaatcttcta ataaagtaaa attggtagat gatttattgg cattcctagc
     6421 accaattacc cacccagaac gccttgg
//
LOCUS       DAVAZT010000085         5482 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVAZT010000085 DAVAZT010000000
VERSION     DAVAZT010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5482
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.085"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..403
                     /locus_tag="VQT45_002004"
     CDS             <1..403
                     /locus_tag="VQT45_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HET2360266.1"
                     /translation="FKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANYYKE
                     GSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPANAY
                     QKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            361..1041
                     /locus_tag="VQT45_002005"
     CDS             361..1041
                     /locus_tag="VQT45_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2360267.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPEIPSPQEPGTPGEPTPEKPIPQPNPEHPSVPTPNPELPNQETPTPDK
                     PTPEPGTPKAETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAGLGLGF
                     FKKKEDEK"
     gene            1264..2133
                     /locus_tag="VQT45_002006"
     CDS             1264..2133
                     /locus_tag="VQT45_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET2360268.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            3044..4240
                     /gene="tuf"
                     /locus_tag="VQT45_002007"
     CDS             3044..4240
                     /gene="tuf"
                     /locus_tag="VQT45_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET2360269.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            4624..5482
                     /locus_tag="VQT45_002008"
                     /pseudo
     CDS             4624..5482
                     /locus_tag="VQT45_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         1769 a         1058 c         1101 g         1554 t
ORIGIN      
        1 ttttaaagaa gcagatacaa attctgcaag tttaactggg aatattgtaa gcgaaggtag
       61 aacagtgacc ttagtttata gagaaagcga agcgccaacc actgctacag taacagccaa
      121 ttactataaa gaaggtagcc aagagaagtt ggcagagtct gttataaaag ctgatttagc
      181 gataggttct gagtatacca cagaatcaaa aactattgaa gggaaaacaa caactgagga
      241 caaagaagac cgagttatca caaggaaaac aacatacacc ttggtagcaa ctcctgcaaa
      301 tgcgtaccag aagacggtgc aacagttgac tattactacc gtgagaatgt tgaggaaaca
      361 gtggttccca aaacagcaac ctctactgag acgaagacta taacgcgtat cattcattac
      421 gttgataaag ttacgaacca aaatgtaaaa gaagatgttg ttcaacctgt aaccttaagc
      481 cgtacaaaaa ctgagaacaa ggtcacggga gttgtaacct acggtgaatg gacaacagga
      541 aactgggacg aggttatatc tggtaagatt gacaagtaca aagatccaga tattccaaca
      601 gttgaatcac aagaagttac gtcagactct agtgataaag aaataacggt aaggtatgac
      661 cgtttatcaa caccagataa accaactcca gaaaaaccag aaattccaag tcctcaggaa
      721 ccaggtactc caggtgaacc gactccagaa aaaccaatcc cacaaccaaa tccagagcat
      781 ccaagtgttc cgacaccaaa cccagaacta ccaaatcaag agactccaac accagataaa
      841 ccaactccag aaccaggtac tccaaaagct gaaactccag tgaatccaga cccagaagtt
      901 ccgacttatg agacaggtaa gagagaggaa ttgccaaaca caggtacaga agctaatgct
      961 accttggcta gtgctggtat catgaccttg ttagctggtc taggattagg attcttcaag
     1021 aaaaaagaag atgaaaaata atagatttta gaatctagga accaggaaaa gatcacagat
     1081 gtgggctttt tcctggtttt gagaatgagg tctttcgtga agaataaaaa cgcttacaag
     1141 tacgttgaac tgggaaacta tgaatcctat ttttttaaaa atatttccag aaatcagttg
     1201 ctaaataggg taaaaattga taaaataagg aatatctaaa aaattttaag gagaatctag
     1261 caaatggatt tcacatgggc actgaagtat gccactgaat ttttgggaac tgccattttg
     1321 atcattcttg ggaatggtgc agttgccaac gttgaactta aaggtacgaa aggtcaccaa
     1381 agtggctgga tcgtcatcgc tgttggttat ggtatggggg ttatgatccc agccttgatg
     1441 tttggtaacg tatctgggaa tcacatcaac cctgctttca ctctagggct tgcagttagc
     1501 ggtcttttcc cttgggcaca agtggtacct tacattatcg cgcaagtctt gggggctatc
     1561 tttggccaag ccttagttgt ggcaacatac cgtccattct acttgaaaac tgaaaaacca
     1621 aataacatct tgggaacttt ctcaactatt tcaagtattg accatggtac aaaagaaagt
     1681 cgctatgcag caactgtcaa tggtttgatt aatgagtttg ttggttcatt tgttttgttc
     1741 tttgcagctc ttggtttgac taaaaacttc tttggtgctg aagtgcttca attcatgaaa
     1801 caaaaggcaa tagaagcagg acaaacagtt gatttttctg acttggctat taaagcacag
     1861 gtggctccac acactgcttc aggactttct gtggctcact tggcacttgg attcctcgtt
     1921 atggctttgg taacatcact tggaggacct acaggacctg ccttgaaccc agcccgtgac
     1981 ttgggaccac gtctccttca tgctttcctt ccaaaatcag ttcttggtga gcataaaggc
     2041 gattcaaaat ggtggtattc ttgggtacca gtagtagcac ctatcgcagc agcaattgcg
     2101 gcagtagctg tattcaaatt cctttatctc taagaaatag ctcctttaac atttgagtga
     2161 gcaccatcta taagtaagag aggatcagac tggttctctc tttttgattt tttagggaaa
     2221 tgaaagaaac tctaaacaaa ctcctctcca gcagtggttt agaagtctca gtgggctatt
     2281 ccagcttcaa tgggctatag taggttgcag ttgaaataat agacccttgt ttctaaaaca
     2341 ttgttagaaa ttggtttgaa ttctccaatc aaattgtgca gttttcattc tactatatat
     2401 tatcggagat gggttcccta tcttgtaagt ctgctttata gtgggttgaa gttggaatag
     2461 tcctcccttc tttctcaaac attgtgagga attgatttac cttcctcaac aaaatgttca
     2521 gtttctattt cattttgcta taaaataagc gattaggggg gctattcttc gacctacatt
     2581 gactctgctg agtcctatga ttgttatcgt tttatctgca attttatact caatgaaaat
     2641 caaagggcaa actaagaagc tagccgcagg ttgttcaaaa cacagttttg aggttgtata
     2701 gtagattgaa actagaatag tacacatcta cttctaaaac attgttagaa atcgatttga
     2761 ctgtcctgat cgatttgctc tattcttgtt tcattttact atataaacca gagactgttt
     2821 acattttcag caagtgagtg gatggataat gctgaaaact ccttgaagga taagtctatt
     2881 tagtactttc tattaattag ttaaattttt accaagaata attcacaaaa acgttgtaaa
     2941 acacttgcaa tttagctgaa atttgataaa atagtaagga aagttagact gtattgccta
     3001 ctgtctatct ataaaatata ttttattgga ggcttttact caaatggcaa aagaaaaata
     3061 cgatcgtagt aaaccacacg ttaacattgg tactatcgga cacgttgacc acggtaaaac
     3121 taccctaact gcagctatca caactgtttt ggcacgtcgc ttgccttcat cagttaacca
     3181 acctaaagac tatgcgtcta tcgatgctgc tccagaagaa cgcgaacgcg gtatcactat
     3241 caacactgcg cacgttgagt acgaaactga aaaacgtcac tacgctcaca tcgacgctcc
     3301 aggacacgcg gactacgtta aaaacatgat cactggtgct gctcaaatgg acggagctat
     3361 ccttgtagta gcttcaactg acggaccaat gccacaaact cgtgagcaca tccttctttc
     3421 acgtcaggtt ggtgttaaac accttatcgt cttcatgaac aaagttgact tggttgacga
     3481 cgaagaattg cttgaattgg ttgaaatgga aatccgtgac ctattgtcag aatacgactt
     3541 cccaggtgac gatcttccag ttatccaagg ttcagcactt aaagctcttg aaggtgactc
     3601 taaatacgaa gacatcgtta tggaattgat gaacacagtt gatgagtata tcccagaacc
     3661 agaacgtgac actgacaaac cattgcttct tccagtcgag gacgtattct caatcactgg
     3721 acgtggtaca gttgcttcag gacgtatcga ccgtggtatc gttaaagtca acgacgaaat
     3781 cgaaatcgtt ggtatcaaag aagaaactca aaaagcagtt gttactggtg ttgaaatgtt
     3841 ccgtaaacaa cttgacgaag gtcttgctgg agataacgta ggtgtccttc ttcgtggtgt
     3901 tcaacgtgat gaaatcgaac gtggacaagt tatcgctaaa ccaggttcaa tcaacccaca
     3961 cactaaattc aaaggtgaag tctacatcct tactaaagaa gaaggtggac gtcacactcc
     4021 attcttcaac aactaccgtc cacaattcta cttccgtact actgacgtta caggttcaat
     4081 cgaacttcca gcaggtactg aaatggtaat gcctggtgat aacgtgacaa tcgacgttga
     4141 gttgattcac ccaatcgccg tagaacaagg tactacattc tctatccgtg agggtggacg
     4201 tactgttggt tcaggtatgg ttacagaaat cgaagcttaa ttcgatttag ttcccagaag
     4261 aacaattatt taagtcagac actaaaagaa tcttgcttgg caaggttctt tttttagata
     4321 ttgaactaat actcaatgaa aatcaaagag caaactataa tatattgaaa ctagaatagt
     4381 acacatttac ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatc gatttgtctt
     4441 gttcttattt cattttacta tagaaagtta gctacagact gctcaaaaca ctgtttttag
     4501 gttgtagata gaactgacga agtcagtaac atctatacga caaggcgaag ctgacgcggt
     4561 ttgaagagat tttcgaagag tataatacta gactaaaatc aaaaagcatt atacaatagt
     4621 aatatgaaat caattaaaga agaaatccaa accatcaaaa cacttttaaa agactctcgt
     4681 acagctaaat atcataaacg tcttcaaatc gttctatttc gtctgatatg ggcaaatctt
     4741 ataaagagat tatagaactt ttagactgta atcaaacaat gatttggcga aatgtaaaaa
     4801 aatatgagga gttcggactc gactctctcc ttcaagaaac acgtggtggt cgtaaccatg
     4861 catatatgac agttgaggaa gagaaagtct ttcttgcccg ccatttgaag gctgcagagg
     4921 caggagaatt tgttacaatt gatgccttat ttcaggctta taaaaaggag ttaggtcgtt
     4981 cctacacacg tgatgccttc tatcaactgt tgaagcgcca tggttggcga aatattatgc
     5041 cacgtccaga acatcctaag aaagcagacg ctcaaaccat tgtcgcgtct aaaaataaaa
     5101 tctcaattca agaagacaag aaagcgtttt aaatatagta gacgttttcg taaggttcgc
     5161 ttgatgtacc aagatgaggc tggtttcggt agaatcagta aactgggatc ttgttgggct
     5221 ccaataggag taggtccaca tatccatagt cactatatac gagaatttcg ctattgttat
     5281 ggagctgttg atgcccatac aggcgaatca tttttcttaa tagctggtag atgtaatact
     5341 gagtggatga acgccttttt agaaaagctt tcacaagctt atccagatga ttatttttta
     5401 ctcgttatgg acaatgctat atggcataaa tcaagtatct taaagattcc gactaatatt
     5461 ggttttgcat ttattcctcc at
//
LOCUS       DAVAZT010000086         4595 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVAZT010000086 DAVAZT010000000
VERSION     DAVAZT010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4595
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.086"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(56..1066)
                     /locus_tag="VQT45_002009"
     CDS             complement(56..1066)
                     /locus_tag="VQT45_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HET2360270.1"
                     /translation="MSFLSKNGAGILACLLISIVSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIDAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKELSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            1215..2384
                     /locus_tag="VQT45_002010"
     CDS             1215..2384
                     /locus_tag="VQT45_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2360271.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQVISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            2381..3151
                     /gene="recO"
                     /locus_tag="VQT45_002011"
     CDS             2381..3151
                     /gene="recO"
                     /locus_tag="VQT45_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HET2360272.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            3148..4140
                     /gene="plsX"
                     /locus_tag="VQT45_002012"
     CDS             3148..4140
                     /gene="plsX"
                     /locus_tag="VQT45_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HET2360273.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            4146..4379
                     /locus_tag="VQT45_002013"
     CDS             4146..4379
                     /locus_tag="VQT45_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET2360274.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQSVGDVVKIIQGK"
     gene            4425..4595
                     /locus_tag="VQT45_002014"
                     /pseudo
     CDS             4425..4595
                     /locus_tag="VQT45_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1349 a          876 c         1174 g         1196 t
ORIGIN      
        1 aacatatata cggcaaggcg acgttgacgt ggtttgaaga gattttcgaa gagtgttaga
       61 aaatgccgat aagggtctgc ataccaagag tggtgaggat gatggcaatc cagcagatgg
      121 ctccaagaag aatggatttt ccactggatt tgaccatagc gaccagattg gttttgagac
      181 cgatagcact catggccatg acaataagga atttagagag ttctttgaga ggggtaaaga
      241 aactactgga cacacctaga gaggtgagta gtgtagtgag gagagaggca aggataaagt
      301 aaaggataaa aagtgggaag acttttttca gttgtaggct ttgcttgttt tcttgttggc
      361 gactttgcca gtaggagaga aagagcgtga tagggataat agccaaagta cgtgtgagtt
      421 taacaatggt tgcagactcg agggtattgc tttggtaaag actgtcccaa gcgctggcgg
      481 cagccgttac agaggaagtg tcgttgaccg cagtccctgc aaagagggcg aagccttcat
      541 tggatagatg aagccaggtg ccgagggttg gaaagatgag cgcagccaag acattgaaga
      601 aaaagataac ggaaatggct tgggctactt ccttttcctt agcatcaata acgggcgctg
      661 tcgctgcaat ggcagaaccc ccacagatag aagaacctac tccaaccaag gtagccagtt
      721 ttgtatccag tgcaaagaaa cgctggaaga ggtaggcaat aatcagagct attgagatag
      781 tggacaggat gacagggagt gaagattggc caactgcgaa gacctgcgag atattgagac
      841 caaaaccaag caagacaacg gcatattgga gcaacttctt ggaactaaag gtcaaaccag
      901 catccagttg tttataggac gagagaaagg gatgtaggag catgcctatg aaaatggcaa
      961 aaacgggcgc gccaatcaca gggaagaatc ctcctaagta ccaagatacg atagaaatga
     1021 gaaggcaggc caagatacct gctccatttt ttgatagaaa tgacataaaa acctccaaat
     1081 aaaatctatt accattatag acctataaac aggaaaagta aaatagaaag tggaaagcta
     1141 ttctctaatg tatttttgcg gtcggggggc ttttgtagta taatagagat acgttttgaa
     1201 agtaggaggt atctatggac ttaactaagc gctttaataa acagttagat aaaattcaag
     1261 tttcgttgat tcgtcagttt gaccaggtta tttcggagat tcctggggtc ttgcgtttga
     1321 ccttggggga acctgatttt acaacgccag accatgtcaa ggaggcggcc aagcgagcga
     1381 ttgatcagaa ccaatcctac tatacaggga tgagtggtct gctgactcta cgtcaggcag
     1441 ccagtgactt tgttaaggaa aagtaccaac tggactatgc tcctgaaaat gaaattttgg
     1501 ttacaattgg ggcgacagag gctttatctg cgactttgac ggctattttg gaagagggag
     1561 acaaggtact tttgccagct cctgcttatc caggctatga accgattgtt aacttagttg
     1621 gggcagaaat tgttgagatt gatacgactg aaaatggttt tgtcttgact cctgagatgt
     1681 tggagaaggc cattttggag cagggtgata agctcaaggc ggttattctc aactatccag
     1741 ccaatccgac aggaattacc tacagtcgag agcagttaga ggccttggca gctgttttac
     1801 gcaagtacga aatttttgtt gtctgtgatg aggtttactc agaattgacc tacacaggcg
     1861 aagcccatgt gtctctagga acgatgttga gagaccaggc tattattatc aatggtttgt
     1921 ctaaatcgca tgccatgaca ggttggcgtt tggggctgat tttcgctcct gcggccttca
     1981 cagcccagtt aatcaagagt caccaatact tggtcactgc cgcaaatacc atggcgcaac
     2041 atgctgcggt agaagccttg acggctggta aaaatgatgc ggagcccatg aagaaggaat
     2101 atatccaacg tcgggactat atcatcgaaa aaatgactgc tcttggtttt gagattatca
     2161 aaccagacgg tgccttctat atttttgcta aaattccagc gggctacaat caagactcct
     2221 ttgcttttct gaaggatttt gctcagaaga aggccgttgc ctttatccct ggtgcagcct
     2281 ttggacgtta cggggaaggc tacgtccgcc tatcttatgc agccagcatg gagactatca
     2341 aagaagccat gaaacgactt gaggagtaca tgagagaagc atgattcagt ctatcacgag
     2401 tcaaggcttg gtgctttaca atcgcaattt tcgtgaggat gacaagctcg tcaaaatttt
     2461 tacagagcag gttggcaaac gcatgttttt tgtcaaacac gctggtcagt ctaagctggc
     2521 gcctgttatt cagcccttgg tgctggcacg atttctcttg cgaatcaatg atgacggact
     2581 cagttacatc gaagactatc atgaggtcat gacttttccc aagattaata gtgacctctt
     2641 tgtcatggcc tatgcgacct atgtggcagc tcttgcagat gctagtttgc aggacaatca
     2701 gcaggatgct cccttgtttg cttttttgca aaagactttg gagttgatgg aagcaggctt
     2761 ggattatcag gttttgacca atatttttga aattcaaatt ttgactcgat ttggaatcag
     2821 cctcaatttt aatgagtgtg tcttctgcca tcgggttggt caggcttttg acttttcttt
     2881 caaatatgga gcctgcctct gtccagagca ttatcatgag gataagagac gttgtcatct
     2941 caatcccaat atcccctatc tgctcaatca atttcaagct attgattttg agactttgga
     3001 gaccatttcg ctcaagcctg gaatcaagca agagctacgc caatttatgg atcaattata
     3061 tgaagagtac gttgggattc acctaaaatc aaagaaattt attgattccc tagcagactg
     3121 gggacaatta ctaaaagagg aaaagaaatg aaaaaaatcg cagtagatgc catggggggc
     3181 gattacgcac ctcaggccat tgttgagggt gtcaatcaag ccctatctga cttttcagat
     3241 atcgaggttc aactttacgg agatgaagct aaaatcaagc aatatctgac agcgacagag
     3301 cgcgtcagca ttatccatac ggatgagaag attgattcgg atgatgaacc tacgagagct
     3361 attaggaata agaaaaatgc cagtatggta ttggcagcca aggctgtcaa agatggtgaa
     3421 gcagacgctg tcctttcggc tgggaataca ggtgccttgt tggcagcagg attcttcatc
     3481 gtgggtcgta tcaagaatat cgaccgtcct ggactcatgt ctaccttgcc taccgttgat
     3541 ggaaaaggtt ttgacatgct agaccttggt gccaatgcag aaaatacagc ccagcacctc
     3601 catcaatatg cggttctagg ttccttctat gctaaaaatg tccgtggcat tgcgcaacca
     3661 cgcgttggtt tgctcaacaa cggaacagag agtagcaagg gcgacccgct tcgtaaggaa
     3721 acttatgaat tactggcggc tgatgaaagt ttgaacttta tcggaaacgt ggaagcgcgt
     3781 gatttgatga atggcgttgc agatgttgtt gtggcagatg gtttcacggg aaacgctgtg
     3841 ctcaaatcca tcgaagggac agctatggga atcatgggct tgctcaagac agctattaca
     3901 ggtggtggtc ttcgagcgaa actaggtgcc ctccttctca aggacagcct cagaggtttg
     3961 aaaaaacagc tcaattattc agatgttggt ggagcggtct tgtttggtgt taaggcacct
     4021 gttgtcaaga ctcatggctc aagcgatgcc aaggctgttt atagtacgat tcgtcagatc
     4081 cgtaccatgc tagaaacaga cgtggttgcc cagactgcgc gtgaattttc aggagaataa
     4141 aagagatgac agaaaaagaa atttttgacc gtattgtgac cattatccaa gagcgacagg
     4201 gagaggactt tgtcgtgaca gaatccttga gtctgaaaga cgatttggat gcggattctg
     4261 ttgacttgat ggagtttatc ttgactctgg aagatgaatt tagtatcgaa atcagcgatg
     4321 aggaaattga ccaactccaa agtgtaggag atgtggttaa aatcattcaa ggaaaatagc
     4381 aatcggagtt ccaagtcaac ggaagtagat ggtttttaga aatgagaaat atcggacaag
     4441 ctggtaaaat cttggctgac agtggttatc aagggctcat gaagatatat cctcaagcac
     4501 aaacttccac gtaaatccag caaactcaag ccgctaacag ttgaagataa agcctgtaat
     4561 catgcgctat ctaaggagag aagcaaggtt gagaa
//
LOCUS       DAVAZT010000087         4583 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVAZT010000087 DAVAZT010000000
VERSION     DAVAZT010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4583
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.087"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..1261
                     /locus_tag="VQT45_002015"
     rRNA            <1..1261
                     /locus_tag="VQT45_002015"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1313..1385
                     /locus_tag="VQT45_002016"
     tRNA            1313..1385
                     /locus_tag="VQT45_002016"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1346..1348,aa:Ala,seq:tgc)
     gene            1510..4411
                     /locus_tag="VQT45_002017"
     rRNA            1510..4411
                     /locus_tag="VQT45_002017"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            4488..>4583
                     /gene="rrf"
                     /locus_tag="VQT45_002018"
     rRNA            4488..>4583
                     /gene="rrf"
                     /locus_tag="VQT45_002018"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1268 a          944 c         1362 g         1009 t
ORIGIN      
        1 atacatagcc gacctgagag ggtgatcggc cacactggga ctgagacacg gcccagactc
       61 ctacgggagg cagcagtagg gaatcttcgg caatggacgg aagtctgacc gagcaacgcc
      121 gcgtgagtga agaaggtttt cggatcgtaa agctctgttg taagagaaga acgagtgtga
      181 gagtggaaag ttcacactgt gacggtatct taccagaaag ggacggctaa ctacgtgcca
      241 gcagccgcgg taatacgtag gtcccgagcg ttgtccggat ttattgggcg taaagcgagc
      301 gcaggcggtt agataagtct gaagttaaag gctgtggctt aaccatagta ggctttggaa
      361 actgtttaac ttgagtgcaa gaggggagag tggaattcca tgtgtagcgg tgaaatgcgt
      421 agatatatgg aggaacaccg gtggcgaaag cggctctctg gcttgtaact gacgctgagg
      481 ctcgaaagcg tggggagcaa acaggattag ataccctggt agtccacgct gtaaacgatg
      541 agtgctaggt gttagaccct ttccggggtt tagtgccgta gctaacgcat taagcactcc
      601 gcctggggag tacgaccgca aggttgaaac tcaaaggaat tgacgggggc ccgcacaagc
      661 ggtggagcat gtggtttaat tcgaagcaac gcgaagaacc ttaccaggtc ttgacatccc
      721 tctgaccgct ctagagatag agttttcctt cgggacagag gtgacaggtg gtgcatggtt
      781 gtcgtcagct cgtgtcgtga gatgttgggt taagtcccgc aacgagcgca acccctattg
      841 ttagttgcca tcatttagtt gggcactcta gcgagactgc cggtaataaa ccggaggaag
      901 gtggggatga cgtcaaatca tcatgcccct tatgacctgg gctacacacg tgctacaatg
      961 gctggtacaa cgagtcgcaa gccggtgacg gcaagctaat ctcttaaagc cagtctcagt
     1021 tcggattgta ggctgcaact cgcctacatg aagtcggaat cgctagtaat cgcggatcag
     1081 cacgccgcgg tgaatacgtt cccgggcctt gtacacaccg cccgtcacac cacgagagtt
     1141 tgtaacaccc gaagtcggtg aggtaaccgt aaggagccag ccgcctaagg tgggatagat
     1201 gattggggtg aagtcgtaac aaggtagccg tatcggaagg tgcggctgga tcacctcctt
     1261 tctaaggata aggaactgcg cattggtctt gtttagtctt gagaggtctt gtggggcctt
     1321 agctcagctg ggagagcgcc tgctttgcac gcaggaggtc agcggttcga tcccgctagg
     1381 ctccattggt gagagatcac caagtaatgc acattgaaaa ttgaatatct atatcaaata
     1441 gtaacaagaa aataaaccga aaacgctgta gtattaataa gagtttatga ctgaaaggtc
     1501 agaaaataag gttaagttaa taagggcgca cggtggatgc cttggcacta ggagccgacg
     1561 aaggacgtga caaacgacga tatgccttgg gtagctgtaa gtaagcgatg atccagggat
     1621 ttccgaatgg gggaacccaa caggtagtac ctgttaccca catctgttaa ggatgtgagg
     1681 aggaagacgc agtgaactga aacatctaag tagctgcagg aagagaaagc aaaagcgatt
     1741 gccttagtag cggcgagcga aacggcagga gggcaaaccg aagagtttac tcttcggggt
     1801 tgtaggactg caatgtggac tcaaagatta tagaagaatg atttgggaag atcagccaaa
     1861 gagagtaata gcctcgtatt taaaatagtc tttgtaccta gcagtatcct gagtacggcg
     1921 ggacacgtga aatcccgtcg gaatctggga ggaccatctc ccaaccctaa atactcccta
     1981 gtgaccgata gtgaaccagt accgtgaggg aaaggtgaaa agcaccccgg gaggggagtg
     2041 aaatagaacc tgaaaccgtg tgcctacaac aagttcgagc ccgttaatgg gtgagagcgt
     2101 gccttttgta gaatgaaccg gcgagttacg ttatgatgcg aggttaagtt gaagagacgg
     2161 agccgtaggg aaaccgagtc tgaatagggc gccttagtat catgacgtag acccgaaacc
     2221 atgtgaccta cccatgagca ggttgaaggt gcggtaagac gcactggagg accgaaccag
     2281 ggcacgttga aaagtgcttg gatgacttgt gggtagcgga gaaattccaa acgaacttgg
     2341 agatagctgg ttctctccga aatagcttta gggctagcgt cgacattaga gattcttgga
     2401 ggtagagcac tgtttgggtg aggggtccat cccggattac caatctcaga taaactccga
     2461 atgccaatga attatggtcg gcagtcagac tgcgagtgct aagatccgta gtcgaaaggg
     2521 aaacagccca gaccaccagc taaggtccca aaataattgt taagtggaaa aggatgtggg
     2581 gttgcacaga caactaggat gttagcttag aagcagctat tcattcaaag agtgcgtaat
     2641 agctcactag tcgagtgacc ctgcgccgaa aatgtaccgg ggctaaaaca atttaccgaa
     2701 gctgtggata cctttatagg tatggtagga gagcgttcta tgtgtgatga aggtataccg
     2761 tgaggagtgc tggaacgcat agaagtgaga atgccggtat gagtagcgaa agacaggtga
     2821 gaatcctgtc caccgtaaga ctaaggtttc caggggaagg ctcgtccgcc ctgggttagt
     2881 cgggacctaa ggagagaccg aaaggtgtat ccgatggaca acaggttgat attcctgtac
     2941 tagagtatgt agtgatggag ggacgcagta ggctaactaa agcagacgat tggaagagtc
     3001 tgtctaagca gtgaggtgtg atatgagtca aatgcttata tctgtaacat tgagctgtga
     3061 tggggagcga agtttagtag cgaagttagt gacgtcacac tgccaagaaa agcttctagc
     3121 gtttaaacat actctacccg taccgcaaac cgacacaggt agtcgaggcg agtagcctca
     3181 ggtgagcgag agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa
     3241 ggggtgctga ctttaagtca gccgcagtga ataggcccaa gcaactgttt atcaaaaaca
     3301 cagctctctg ctaaatcgta agatgatgta tagggggtga cgcctgcccg gtgctggaag
     3361 gttaagagga gtgcttagcg taagcgaagg tatgaattga agccccagta aacggcggcc
     3421 gtaactataa cggtcctaag gtagcgaaat tccttgtcgg gtaagttccg acccgcacga
     3481 aaggcgtaat gatttgggca ctgtctcaac gagagactcg gtgaaatttt agtacctgtg
     3541 aagatgcagg ttacccgcga caggacggaa agaccccatg gagctttact gcagtttgat
     3601 attgagtgtc tgtaccacat gtacaggata ggtaggagtc taagagatcg ggacgccagt
     3661 ttcgaaggag acgctgttgg gatactaccc ttgtgttatg gccactctaa cccagatagg
     3721 tgatccctat cggagacagt gtctgacggg cagtttgact ggggcggtcg cctcctaaaa
     3781 ggtaacggag gcgcccaaag gttccctcag aatggttgga aatcattcgc agagtgtaaa
     3841 ggtataaggg agcttgactg cgagagctac aactcgagca gggacgaaag tcgggcttag
     3901 tgatccggtg gttccgtatg gaagggccat cgctcaacgg ataaaagcta ccctggggat
     3961 aacaggctta tctcccccaa gagttcacat cgacggggag gtttggcacc tcgatgtcgg
     4021 ctcgtcgcat cctggggctg tagtcggtcc caagggttgg gctgttcgcc cattaaagcg
     4081 gcacgcgagc tgggttcaga acgtcgtgag acagttcggt ccctatccgt cgcgggcgta
     4141 ggaaatttga gaggatctgc tcctagtacg agaggaccag agtggactta ccgctggtgt
     4201 accagttgtc ttgccaaagg catcgctggg tagctatgta gggaagggat aaacgctgaa
     4261 agcatctaag tgtgaaaccc acctcaagat gagatttccc atgattatat atcagtaaga
     4321 gccctgagag atgatcaggt agataggtta gaggtggaag tgtggcgaca catgtagcgg
     4381 actaatacta atagctcgag gacttatcca aagtaactga gaatatgaaa gcgaacggtt
     4441 ttcttgaatt gaatagatat tcgattttga gtaggtatta ctcagagtta agtgacgata
     4501 gcctaggaga tacacctgta cccatgccga acacagaagt taagccctag aacgccggaa
     4561 gtagttgggg gttgccccct gtg
//
LOCUS       DAVAZT010000088         4576 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVAZT010000088 DAVAZT010000000
VERSION     DAVAZT010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4576
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.088"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..160)
                     /locus_tag="VQT45_002019"
     CDS             complement(<1..160)
                     /locus_tag="VQT45_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HET2360275.1"
                     /translation="MNIKKRVLSAGLTFASVLLLAACGQSGSDTKTYSSTFSGNPTTF
                     NYLLDYYTD"
     gene            complement(318..1925)
                     /locus_tag="VQT45_002020"
     CDS             complement(318..1925)
                     /locus_tag="VQT45_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HET2360276.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLVRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            2078..3562
                     /locus_tag="VQT45_002021"
     CDS             2078..3562
                     /locus_tag="VQT45_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HET2360277.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFLNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGISPADRKVAVVARQKAEETGGPALALELPNGDIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            3657..4139
                     /locus_tag="VQT45_002022"
     CDS             3657..4139
                     /locus_tag="VQT45_002022"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HET2360278.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(4425..4576)
                     /locus_tag="VQT45_002023"
                     /pseudo
     CDS             complement(4425..4576)
                     /locus_tag="VQT45_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT         1319 a         1058 c          866 g         1333 t
ORIGIN      
        1 tatcagtgta atagtctaat agatagttaa atgtagttgg atttccacta aaggttgatg
       61 agtaagtttt tgtatctgaa cctgattggc cgcaagcagc taaaagcaaa acagatgcaa
      121 aagtcaggcc tgcactaagg acacgcttct ttatgttcat cttctttctc cttaatagtg
      181 ggaatttgta aagttaattg aatttcgaga atgaaagttt ataaaccttg gttataaaaa
      241 acaaaggatt tctgctttta tacagtcctc ccttgttttt atatgatttc aattttaaat
      301 ttttctgcaa aaaatattta tagtaattcc acacagaaag catcccatgg aactaagatt
      361 tgtttttcaa agacttcttg agctagggtg ttttcaatca agacagattt gacttttcct
      421 tctactgtca agtcttgctc ttcattggac aagttagcca caactaggaa gcgacggtcg
      481 ccatccttac gtatataagc aaagacctta tcagccgtat caagcaattc aaagtcagct
      541 cgaactagcc agctattctc cttgcgaatt tggaccagtt tctgataggt atagaaaata
      601 gaatctggat ttgccagcgc ttcttggaca ttgatcatct cgtaatttgg attaaccgcc
      661 aaccaaggtt gacctgttga gaaaccagcg tttttgctct cgtcccattg cataggggta
      721 cgggcattgt cacgtccaat aacacggata ctgtccatga tttcttcaat cggaacacct
      781 ttttcaagag cctcacgcgc atagttgaga gattcaatat cttctacttg atccagtgtt
      841 tcaaacggat agttggtcat cccaatctcc tcaccttggt agatataagg agttcctctc
      901 ataagatgaa gcaagattgc aaaggctttg gcagattttt cgcggtattc ttggtcattt
      961 ccccagattg agacaatacg agggaggtca tggttgttcc agaagaggga attccagccg
     1021 tcctcaactc ctaactctgt ctgccatttg ttgaagattt cttttaactt agcgatattc
     1081 agctcttttt gatagtgcca tttaggctga ccttcctgat actgaagacc gatatgttca
     1141 aactggaaga ccatagacaa ttcttgcccc tttggatcag agtagagctt ggcaatctct
     1201 ggcgttgctc cccaagtctc ccctactgtc aagagatcct tatctccaaa ggtcgcctga
     1261 ttcatttcct tgagataggg atggagcata ggaccattat tgactacctt ctcgtcagga
     1321 attttgccaa tcatgtcaat aacatccata cggaaaccac caataccctt atcaatccag
     1381 aagttcatca tctcataaat tttctggcga agtttttcat tttcccagtt gagatccggc
     1441 tgtttcttgc tgaaaaagtg gagatagtat tgacctgact tttcatcgta ttcccaagca
     1501 gacccactaa agatagaatc taaatcgtta ggctcatccc gccagatata gtagtctcgc
     1561 tcagggctat taggattttc acaggcctct acaaaccagg catgctcatc cgaggtatga
     1621 ttgaccacca agtccatgat gatacggata tcacgcttct tagcttctgc aatcagctga
     1681 tccatgtcct ccatggttcc aaaaatagcc gcaatcgctt gataatcagc aatatcgtag
     1741 ccattatcat ccatagggct gtcataaacg ggagaaagcc aaattgctgt gattcctagc
     1801 ttggctagat agtccaactt actggtaatt cctggcaaat cgccaattcc atctccatta
     1861 ctatccataa aactctttgg atagacttga tagactacgg cattatgcca ccatttttct
     1921 tgcatctgtt tacctcatta ttttcataat ctatagtcta tgatagcact ttttaaaatt
     1981 ttgtgcaagc gtttgcttaa tctttttaat ttctttttta gctccgtagt ttcctaactt
     2041 ccaatttttt attataatag agtccagagg taaaaaaatg aaaaaacaag cttttagttc
     2101 tgaacagtat ttgaatttac aacgcgacca tattttggag cgcattaacc aatttgacgg
     2161 caagctctac ttagagtttg gcggtaaaat gttagaagat ttccacgctg ctcgtgtcct
     2221 tcctggttat gaacctgaca acaaaatcaa gctcttgcaa gaattgaaag agcaggttga
     2281 ggttgtgatt gccattaatg ctagcaacat tgaacattcc aaagcacgtg gcgacttggg
     2341 catttcttat gaccaagaag ttcttcgttt gattgacaaa ttcaatgaat tagggatttt
     2401 tgttggttcc gttgtcatta cacaatacgc tggccaaccc gctgcagatg ccttcctcaa
     2461 ccaacttgag aaaaacggaa ttgattctta tcttcattat ccaatcaaag gatatccgac
     2521 ggatatggat cacatcattt ccccagaagg catgggcaaa aacgactaca tcaaaaccag
     2581 tcgcaacttg attgtcgtaa ccgctcctgg acccggttct ggaaaattgg caacgtgtat
     2641 gtccaatatg taccacgacc aaatcaatgg catcaagtct ggctacgcta aatttgaaac
     2701 cttccctgtt tggaatcttc cccttcatca tccagttaac ttggcttatg aagctgccac
     2761 agctgacctt gatgatgtca acatgattga ccccttccat cttcaaacct atggagaaac
     2821 cactgtcaac tacaaccgtg atatcgaaat cttcccagtg ctcaagcgca tgttggaacg
     2881 tattctcgga aaatcaccat acgcttcacc gacagatatg ggtgtcaaca tggttggttt
     2941 cgctattaca gatgacgagg ctgctgtcga agcttctaaa caagaaatca tccgccgtta
     3001 ctatcaaaca gttcttgact tcaaagctga aaaagttggc gaagctgccg tcaagaaaat
     3061 tgagttgctc atgaacgacc tcggtatctc acctgcagac cgtaaggttg ctgtcgttgc
     3121 gcgccaaaaa gcagaagaaa ctggcggacc agccctagct cttgaattac caaatggtga
     3181 cattgtcact ggtaaaaact cagaactctt tggccctaca gccgctgcct tgatcaacgc
     3241 catcaaaaaa tcagctgaca tcgctaaaga agtaaaacta atcgagcctg aagttgttaa
     3301 gccaatccaa ggacttaaaa tcgatcatct cggtagccgc aatccacgcc ttcattcaaa
     3361 tgaaatcctg attgcacttg ctatcacagc tacagaaaat cctgatgctg cccgcgctat
     3421 ggaagaactc ggcaacctca aaggaagcga agcccactca accatcatct tgactgatga
     3481 agacaagaat gtccttcgta aactgggtat caacgtaacc tttgacccat actaccaata
     3541 cgaccgctta tatcgtaagt aaagatttca acctctccag cctcggagag gttttctctc
     3601 tgtctcagga gcaagcttta tgatataatg agagaagaaa actgaaagga tttaccatgt
     3661 caaaagaagt tattgtcgaa agttttgaac ttgaccacac cattgtcaaa gcaccctatg
     3721 ttcgcttgat tggggaagaa acaggaccaa aaggagacat catctccaat tatgatattc
     3781 gcttggtgca accaaacgaa gactctatcc ctactgccgg ccttcacact atcgagcacc
     3841 tcttagccaa actcatccgt acccgcattg acggcatgat tgactgttca ccatttggtt
     3901 gccgcacagg cttccacatg attatgtggg gacgtcacac cagtgctaaa atcgcagctg
     3961 ttatcaagga ttcgctcaag gaaatcgctg aaactactac ttgggaagat gtcccaggga
     4021 caaccatcga atcttgcgga aactacaagg accacagcct cttctctgct aaagaatggg
     4081 caaaactcat cttggaacaa gggatttcag atgatgcctt tgaacgtcat gtgatttaaa
     4141 atcgagtagg ggataatctc tagcccctct cacaccaccg tacgtgccgt tcggcatacg
     4201 gcggttcaac taacttttaa cgcatgtcgt tcaaggtaat aatccaaaca cgaaaccaat
     4261 ccacgttttt caaggactgg ttttgatata gcacgtttaa gtaccgactt ctgagctact
     4321 atagtggatt gaaactagaa tagttcacct ctgcttctaa aacattgtta gaaatcgatt
     4381 tgactatcct gatcgatttg ttctattctt atttcatttt actataattg atagtggtcg
     4441 ccccagccag ataccttatc tgctatccat ttaggaaccc ctaacttaag caatccccat
     4501 aatcgtctcg atttcttctt ccattgcttc cagataatca ctcgtaggcg agtatgcaaa
     4561 cgctcatcta tgctgg
//
LOCUS       DAVAZT010000089         4552 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVAZT010000089 DAVAZT010000000
VERSION     DAVAZT010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4552
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.089"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(112..549)
                     /locus_tag="VQT45_002024"
     CDS             complement(112..549)
                     /locus_tag="VQT45_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HET2360279.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(634..3267)
                     /gene="polA"
                     /locus_tag="VQT45_002025"
     CDS             complement(634..3267)
                     /gene="polA"
                     /locus_tag="VQT45_002025"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HET2360280.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            3520..3873
                     /locus_tag="VQT45_002026"
     CDS             3520..3873
                     /locus_tag="VQT45_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET2360281.1"
                     /translation="MILRHLGISPTNDLVAKKIFSNPEITCQFIRDMLDLPAKNVTIL
                     EGSNIHVLPSMPYSAQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQV
                     NQNLEKIRQREGDTH"
     gene            4088..4204
                     /locus_tag="VQT45_002027"
     CDS             4088..4204
                     /locus_tag="VQT45_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET2360282.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            4197..4430
                     /locus_tag="VQT45_002028"
     CDS             4197..4430
                     /locus_tag="VQT45_002028"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360283.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
BASE COUNT         1385 a         1096 c          837 g         1234 t
ORIGIN      
        1 gtatctacaa cctcaaaaca gtgttttgag cagcccgcga ctagtttcct agtttgctct
       61 ttgattttca ttgagtataa cacaaaaggt agcccatcag ctaccttttt cttatgcttc
      121 ctcaatcaag cgagtatgtt ctctcttgat acagcgattc atcacgatat catcacatcc
      181 accatcacgc aaaatctctt tcgcttctaa actttcaagt cctagctgtg cccaaaaaat
      241 cttggcatca gctttgagaa aatcacgcgc cacatcgggc agaaattcac tgcgacgata
      301 aacattgaca atatctacag gaaaaggaat ttcagcgagg ctagcataag ccttttcacc
      361 caagatttcg ccacctgccg ccttgggatt gactgggatg attttatagc cccgagcctg
      421 catttccttt gtcactcgat tgctggttgt ttcttcacgg tcagacaaac ccaccacagc
      481 aagggtttta ctcgttgcga gatactgacg aatcacgcca tcacttggat tgataaattc
      541 ttgactcata gaaaacctcc tttttcatca gtatagcaca ttttgaaaag gtttgcagaa
      601 ttctactaca aaaaaggagg actagccccc tttttattta gcctcgtacc aggttgcccc
      661 ttcattctca tctgcgataa gaggaacact gagttgaatg gcttcttcca tggtttgttt
      721 caccaatttt ttcatctcta ccaattcaga tttaggcact tcaaggacga tttcatcgtg
      781 cacttgtaac agcatcttag tctgataacc acctgcaacc aaggctttat ccagctgaat
      841 catggcaatc ttgagaatat ctgctgccga accctggata ggtgagttga tagcagttcg
      901 ctccgcaaaa ccacgaatat tgaagttgcg cgaattgata tctggcaact cacggcgacg
      961 cttaaagagg gtctctacat agcccttatc acgcgcctcc cgcaccactt catccatgta
     1021 gtttttaata cctggaaaac gttcaaagta ggtatcaatg taggctttgg cttccttacg
     1081 actaattccc aaattattag acaagccaaa gtctgaaatc ccataaacca ctccaaagtt
     1141 aactgccttg gcattgcgac gatcatttgc agtcacatta tcaggacgct caatgccaaa
     1201 gacccgcatg gctgtcgaag tatggatatc tgccccctct tggaaggcct taatcaagtg
     1261 ctcatcctta gaaatatgcg ccaaaacgcg caattcaatc tgtgaatagt cagagctgag
     1321 tagcacacta tcctcccact ctggcacaaa agccttccga atcaagcgcc cttgttccaa
     1381 tcgggcagga atattttgca agtttggatc cacactagac aaacgcccgg tctgggtcaa
     1441 atcctgcata tagcgagtat gaatctttcc atcagccaaa atccagtcct gcaagccaat
     1501 tacataagta gattgaatct tagcaatttg acggtaatcc aggattttct taacaatcgg
     1561 agcaatagga gcgagacgct ccaacacatc cactgctgtc gaataacctg tcttggtttt
     1621 cttagtgtat tctagaggaa gtcccaattt ctcaaagaga agcacgccca actgcttagg
     1681 cgagttgaca ttaaactcct caccagccag ctcgtaaatc tcttgagtca gtttttcaat
     1741 gacaagctca ttttcagcct gcatctcaag caaggtctct ttcttgacca caatcccagc
     1801 aatttccatc ttggcaagaa caaaagccag aggttgctcc atatcataaa gaagctctaa
     1861 ttgcccattt tcgctgagtt tttcaagtaa aataggctct gtttctacca aaacagcaag
     1921 tttacaagct aagtgttcca agaatttctc acgttcagga atggcctttt taacaccctt
     1981 accgtagaaa gtttcatcat caaccaagta agtctgacca taaagactag cgatggtcgc
     2041 aatttcattg tcctccacag tcgaaaggag gtatttagcc aaacggatgt caaaagcagg
     2101 cgcctgcaaa tccacaccaa aacgttgcaa aagaacttta accttcttaa agtcataaac
     2161 tctcagagat gttttttcta agaaatcctt gaaaatcggg tcttgcaaca gctcaagctt
     2221 gtctgtggca tagagcttat ccccacaaga ccaggcaaat ccaaccaaat tatccgtatg
     2281 ataattctca ccaaaaagct caaagtggaa gatagactct tcactcagca tatcttgact
     2341 gatttggtca acaatagtaa aatccaaacc ctcagccaca tcagctgacg acacatttaa
     2401 agcctgcttg agctgtttga atcccatctc atcgtaaaat ttcccaagat tttcaacatc
     2461 tggaccacta tagaccaagt cctctaaacc aatcgcaatc ggtgccttgg tatcaatggt
     2521 cgctagtgtt ttagacaaaa aggcctgttc cttgtcattg atgagatttt ccttcatctt
     2581 agaagtcttc attccatcaa tattttcata aatcccctca agcgaaccat gctccagcaa
     2641 gagcttaata cccgtctttt caccgacttt ggtcacccca gggatattat ccgacttatc
     2701 acccatgagc gccttgagat cgataaactg agctggtgtg aggcccattt cttccatgag
     2761 gtaatctggc gtaaaggcct caaactcagc cacacctttc ttggaaattt caaccaccgt
     2821 atgctcatcc gtcagctgaa tcaaatcctt gtccccactg acaatggtaa tatcaaaacc
     2881 atcctgctct gctagcttat ccaacgtccc aatgatgtca tccgcctcat actgagccag
     2941 ctcatagtga cgaatcccca tatgatccag caactcacga atgaaaggaa attgctcacg
     3001 aaactcatca ggagtcttgg cccgaccacc cttatagtcc gcatacatct ctgtccggaa
     3061 ggtcgtcttt cccgcatcaa aagccaccaa aatatgactc ggctcaaccc gctccaacaa
     3121 atgactcaac atcaactgaa aaccataaat cgcattggta tgcaaaccag ccgcattctt
     3181 aaaacggtcc aactgctgat acagcgcaaa aaacgcccga aaagctacag aagacccatc
     3241 aatcaataat aattttttct tatccataca cccattataa aggaaagaat caaaaaatac
     3301 cattgggaag agctagagca agtatttttc aaactttttc cgaataaata gatagagcca
     3361 gagaatttag taaacctaga tttaaaaatg tgctataata tagtatattg aatctataat
     3421 agtacacctt gactgctaaa atatttctat aaattaattt gactttcctg atagagttgt
     3481 tcacatctta tttcaattca ctatagaagg aggaaaagga tgattctcag acatctggga
     3541 attagcccga ccaatgactt ggttgctaag aaaattttca gcaacccaga aatcacttgt
     3601 caatttatcc gcgatatgct ggacttgcca gccaaaaatg tgactatttt ggagggaagt
     3661 aacattcatg tcttgccttc catgccctac tcagcgcagg atttttatac cagtatagac
     3721 gtcttggcgg agttggataa cggtactcaa gtaattattg agattcaagt ccatcatcag
     3781 aattttttca tcaatcactt gtgggcttac ctgtgcagtc aggttaatca aaatcttgaa
     3841 aaaattcgtc agcgagaagg tgatactcac tagatctaca aacacatcgc tcctgtttac
     3901 gtcattgcta tcgtggatag taattatttc tcagatgacc tggcttttca tagctttagt
     3961 atgcgcgaag acacaacagg tgaggtattg gcgattacca acaatggaca ggaaaaccat
     4021 ctggttaaga tggcattctt ggaattaaaa aatacagaga aaccagcaaa gacaaggttc
     4081 gcaagccatg gttggagttt ttcggcaaca agccctttac ccagcaaccg caacgagcca
     4141 ttacccaagc aaatcaactg ctggactaca agagctggtc cgaggaggac aggaaaatgt
     4201 ttagtcaact acatatgcga gaagaacaag tcttgttagc acaggactat gccttggaaa
     4261 ctgctagggc tgaaggcctt gaacaaggac tagagcgtgg gaaagttgaa ggaagggcag
     4321 aaaggaaact ttttgccttc ctagacatag tacgccaagg tcttctgact tctgaggttg
     4381 ccagccagca attaggtatg tcagtatctg aatttgaggc actgttgtaa aatggctcca
     4441 taatatccat agtgggtaaa tcccctatgg atattatgga gcctattttt gtgtagaaaa
     4501 aaagtcccat atgacctata atgaaaagcg acaaaacaac tcattaaaaa ga
//
LOCUS       DAVAZT010000090         4438 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVAZT010000090 DAVAZT010000000
VERSION     DAVAZT010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4438
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.090"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..119
                     /locus_tag="VQT45_002029"
     CDS             <1..119
                     /locus_tag="VQT45_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2360284.1"
                     /translation="QQGFTDRLVGYSSSIALVFTTLIGMISLVQRRVLKEDD"
     gene            121..966
                     /locus_tag="VQT45_002030"
     CDS             121..966
                     /locus_tag="VQT45_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2360285.1"
                     /translation="MKRFKPTTILEYILLTLLAGLFLFPMVWMVVSAMKPEADVYKNL
                     TSWQAFLPSLNPADWFKPYQEVFERFSIFTYLGNSIFYAGTFAIGSIIVNALAGFAFA
                     KVNFSGKKILFGFLLALLIIPVETVLIPQFTIINSLGLVNNRLAVIIPGLASVFNIYL
                     FRNFFIAIPEEILESAKMDGASIVRIFFRIMLPMSKPAVATVGVLSFISSWNDYIWPL
                     MVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTISTIPLILVYVVAQKYIVQGLGGS
                     GTGIK"
     gene            976..2295
                     /locus_tag="VQT45_002031"
     CDS             976..2295
                     /locus_tag="VQT45_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET2360286.1"
                     /translation="MINKTFTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGGEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWREKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(2503..2575)
                     /locus_tag="VQT45_002032"
     tRNA            complement(2503..2575)
                     /locus_tag="VQT45_002032"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2540..2542),aa:Lys,seq:ctt)
     gene            complement(2839..4110)
                     /locus_tag="VQT45_002033"
     CDS             complement(2839..4110)
                     /locus_tag="VQT45_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HET2360287.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWIKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
BASE COUNT         1294 a          809 c          976 g         1359 t
ORIGIN      
        1 atcaacaagg ttttactgat cgtcttgtag gatattctag ctcaatcgct ttagtattta
       61 caacgttaat tggtatgatt agcttagtac aacgtcgcgt tctgaaggag gatgactaag
      121 atgaaacgat ttaaaccaac aacaatctta gaatatattc tgttaacttt attggcagga
      181 ctcttccttt ttcctatggt ttggatggta gtttcagcta tgaagccaga agcggatgtt
      241 tataaaaatt tgactagttg gcaagccttc ttaccaagtt taaatcccgc tgattggttt
      301 aaaccttatc aggaagtatt tgagcgcttt agtattttta catatctagg gaacagcatt
      361 ttttatgctg gaacgtttgc tattggttct attattgtca atgcactggc cggtttcgct
      421 tttgcaaaag tcaatttttc aggtaagaaa attttatttg gtttcttact tgctttactt
      481 attattccag tggaaactgt gttaattcca caatttacca ttatcaattc cttaggtttg
      541 gtcaataatc gtcttgcagt tattattcca ggattggcga gtgtatttaa tatttactta
      601 tttaggaatt tctttattgc aattccagaa gagattcttg agtctgcaaa gatggacgga
      661 gcaagtatcg ttagaatttt ctttagaatt atgcttccaa tgtctaaacc tgcagttgct
      721 acagttggtg ttttatcatt tatttcaagc tggaatgatt atatctggcc attgatggtt
      781 ttgacagatt cttctaaatt ttcaatgcag gttgcaatta caactattaa tacaactcaa
      841 ccagtttata tcaatcaggt aatggctgta ttaactattt caacgattcc gttgattttg
      901 gtctatgtag tcgctcagaa atatattgtt caaggtctgg gtggttccgg aactggaata
      961 aaataggata tacttatgat aaataaaaca tttacagtag aaaaagccaa tcgttttata
     1021 gcagaaaata aacatctcgt taatactcaa tataagcctg aagaacattt ttcagctgag
     1081 attggttgga tcaatgatcc aaatggattt gtctattttc gtggagaata ccatctcttt
     1141 tatcaattct atccatatga tagtgtttgg gggcctatgc actggggaca tgctaaaagt
     1201 aaggacttgg tgacttggga gcacttgcca gtggcacttg ctcctgacca agattatgac
     1261 cgaaatggtt gtttctcagg ctctgccatt gtcaaggatg atcgcctctg gctcatgtac
     1321 actggacata tcgaagaaga aaccggtgtc cgccaagtgc aaaatatggc attttcagat
     1381 gacgggattc actttgaaaa gatttcccaa aatccagttg caactggatc agacttgcca
     1441 gatgagttga ttgctgctga tttccgtgat ccaaaactct ttgaaaaaga tggacgctat
     1501 tactccgtag tagctgccaa acacaaggat aatgtgggct gtatcgttct actagggtcc
     1561 gataacctag tagaatggca gttcgaatcc atctttttaa aaggaggaga acaccaaggc
     1621 tttatgtggg aatgcccaga ttacttcgag ttagatggga aagattgcct tattatgtca
     1681 cccatgcgtt atcagcgtga gggagactca tatcataaca tcaactcatc gcttttgttc
     1741 acgggtaagg tagattggag agaaaaacgt tttatcccag aatcagttca agaaattgat
     1801 catggccaag acttctatgc gcctcaaaca ttgttggacg atcaaaatcg tcgtatcctg
     1861 attgcttgga tgcagacatg ggggcgtacc cttccaaccc atgaccaaga acacaaatgg
     1921 gcatgtgcca tgactttacc tagaattcta agattggaag atggcaaact aagacaattc
     1981 cctgttaaaa aaggccaata tcaaatccaa atagataaag attgtcatta ccacttagga
     2041 aatgatacag attatcttga atttggttat gacagtaatg cgcagcaagt ttacattgat
     2101 cgtagccatc ttattcaaaa aattctaggt gaagaagaac aggacactag tcgacggtat
     2161 gtagatattg aagctaaaga attggaagtt gttctagata aaaattccat cgagattttt
     2221 gtcaatcaag gtgaagcaag cttgactgca acttattact taacggtgcc agctgagcta
     2281 tcacgaattg attaaaaatt aagttatttc tcctaaagaa aaagttctct ttctaaaata
     2341 gtggaaagag gactttttgt gttttgggta tataagctta gtttatggta tttgtaaaat
     2401 tggtgttgga ttatgattta agctagtttt ctaaagaatt tgaaaaaaat tttatttaag
     2461 caaaaaaacc ttggttccaa ggcttttcct gttgtattta gatgccccct acagggatcg
     2521 aacctgtgac ccacggatta agagtccgct gctctgccag ctgagctaag gaggcaaaga
     2581 aaaagctgta ttggtgccga aacttcacgg tttgtattga acccgcgcaa ttaagcaggt
     2641 gggcaactcg ctctaactga agctgtttcc gtgtgagacg gcctacatgc tgttagaaga
     2701 cttttgtttc cctaataata caaaaaatag tcggtcaaca cttaagtgtg aagtcgtaca
     2761 ccacagcgtt tctatactta tatgatacca ctttttcaaa aaaaatcaag aggaaagtgc
     2821 aattttttga aaaggatttc agatttttcg caaacgatcg atagcttcct ttctttgagc
     2881 caaagcccgt tcatatttac cagtatcttc tgcttggaaa tagtgatgat tacgaatttt
     2941 ttctggcaga tagtcttgct tgatccaatt tccaggatag ttgtgtggat agagatagtc
     3001 ttgggcattc cccagttcct tgcttccact gtagtgccca tcacgcaggt gtcgcggaat
     3061 aggcaagtgc cctgatgttt tgaggtcagc aagtgcctta tccatagcta cataggctga
     3121 gttggatttt ggagaaaggg ccaaatcaat cacgacattg gcaatgagaa tgcgggcttc
     3181 ggggaaacca atcctttgtg cagcatccag agcagtcacg gtatgaatct gggcctcagg
     3241 attggctaag ccaatatctt cataggcgat aacagtcaag cgacgagcga gactaggcag
     3301 atccccagcc tcaatcaagc gggcagcata gtggagactg gcatccacat ctgagccacg
     3361 gatagacttt tgcagggcag atagaacatc atagtgaccg tctccatcct tgtccatagt
     3421 gatgtagctt ctctgaagac tattttccat gatgtctaag gtgatgtggc gaatgccctc
     3481 gtcattctca ggggtagaga gaacagccaa gtccagtgag ttaaaggcag agcgaaggtc
     3541 tccgtttgta gaggttgcga tgaaatccag cgcatcctca tctagttcta ttggaaaatc
     3601 aaaaccacgt tcagggttac ttagagctat ctgcagggcc tctttgacgt cttggttaga
     3661 cagaggttcc aactcgaaaa tttgaacacg gctacgaatg gcaggagtga cagagaagaa
     3721 aggattttca gtcgttgctc caatcatgat gaccagtcca ctttccaaga gaggcaagag
     3781 gaagtcttgc ttggtcttat ctagtcgatg aatttcgtct agcaatagga cgagaccacc
     3841 agaaaattta gcttcttccg agatttcttg cagtcgcttt ttactatcaa ctgtcgcatt
     3901 gaaagttcga aaggcatact tggtcgttcc agcgatggca gaggcaatac tggttttgcc
     3961 gattccagga gggccatata gaatcatgga ggacaggcgg ttggcttcca ccatgcggcg
     4021 gatgattttt ccaggtccga ccagatgctc ctgaccgatg acctggtcga tggttttagg
     4081 gcgcatgcga agcgcgagat tgtctggcat agcagtcctt tctaacgtgg atttgagtag
     4141 aatgactcat ctactatatc ttactatgtc cattctagcc tattagttgt gatatttcaa
     4201 tggttttgta ataatcaggg agtgagatag aatctttttt actatttaat ttaatgagga
     4261 gaggtatcag catgagagat ttgattttcc ttaaagctca aaataggata gttgagccta
     4321 aagaagtgga agtgctgact tgagaaataa tattgctgaa tgtcattgta tgaactataa
     4381 tgaaaagaga ggtgataagc aatggaaatg atggaccaag tcaggaaatt ttgatttt
//
LOCUS       DAVAZT010000091         4411 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVAZT010000091 DAVAZT010000000
VERSION     DAVAZT010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4411
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.091"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(139..573)
                     /locus_tag="VQT45_002034"
     CDS             complement(139..573)
                     /locus_tag="VQT45_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2360288.1"
                     /translation="MLLVLVSLVHSFGSVSIIAHTIHQKFNLKVPNYRQEEDWARMGL
                     PITRKEISNWHIKASQYYLESLYKLLREKLLEQPLLHADETSYRVLESDSHLTYYWTF
                     LSGKAENQAITLYHHDQRRSGLVVQEFLGDYSGYVHCDMLRQ"
     gene            complement(649..1500)
                     /gene="rfbD"
                     /locus_tag="VQT45_002035"
                     /pseudo
     CDS             complement(649..1500)
                     /gene="rfbD"
                     /locus_tag="VQT45_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647909.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
     gene            complement(1566..2615)
                     /gene="rfbB"
                     /locus_tag="VQT45_002036"
     CDS             complement(1566..2615)
                     /gene="rfbB"
                     /locus_tag="VQT45_002036"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HET2360289.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLVAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGIYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            complement(2625..3221)
                     /locus_tag="VQT45_002037"
     CDS             complement(2625..3221)
                     /locus_tag="VQT45_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HET2360290.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     VLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENLEEADVSEADKHHPLLKDVKPLKKEDLE"
     gene            complement(3222..4079)
                     /gene="rfbA"
                     /locus_tag="VQT45_002038"
     CDS             complement(3222..4079)
                     /gene="rfbA"
                     /locus_tag="VQT45_002038"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HET2360291.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLHRFQELLQDGSEFGIKLSYAEQPSTDGLAIGEEFISDDSVALIL
                     GDNIYHGPGLSTMLQKAAKKEKGATVFGYQVKDPERFGVVEFDTDMNAISIEEKPEYP
                     RSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRGFAWL
                     NTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQPLKKNEYGQ
                     YLLRLIGEA"
BASE COUNT         1263 a         1014 c          792 g         1342 t
ORIGIN      
        1 ccaacatcca acaagttcag cttcttccag ttgacgataa gcttctagcg gttcgcagtt
       61 taccaagctt agcgtcgcct tgctcctaaa ccttggactg ctatcgcata ggcagaacta
      121 gaggactaaa gtcctaagtt actgccgcaa catatcacaa tgcacatagc cagaataatc
      181 tcctaggaat tcttgtacta ctaaaccact ccgacgctga tcatggtggt acagcgtgat
      241 tgcttgattc tcagctttcc cagacaaaaa agtccaatag taggtcagat ggctatcact
      301 ctctagaacc cgataagagg tttcatccgc atgaagaaga ggttgttcta acaacttttc
      361 tcgtaaaagc ttataaaggg actctaaata gtattgactt gccttgatat gccaattaga
      421 gatttcctta cgtgtgattg gtaaacccat cctagcccaa tcttcttctt ggcgataatt
      481 gggtaccttc agattaaact tctgatggat ggtgtgagcg ataatagaaa ctgagccaaa
      541 gctatgcacc aaagagacca gcaccaacaa caagataatt gtacatctta agctcctttg
      601 gagttcatta tctgcctctt ttattagact agaaaatcat tctactactt atctcacttc
      661 ttgtttgtaa aattcttgca atgcatcttg ccaagttgga ataacaaatc cagtagcttt
      721 ggctttggcc aggctcatcg ttgagtttag cggacgttga gctttggctg gaaattgact
      781 ggaatctact ggcttgactt cgacatctgt atctttcaaa atttcaactg caaaatcata
      841 ccatgttgtg tcttctgtcg catcatttga caaatgataa taaccaaatt ccttacgatt
      901 ttcagctagg tagatcatga attcagccaa ggtacgagtc caagtcggac gaccgtactg
      961 gtcatttaca actgttaaag tcttatgagt tttcgcaaga ttttgcatgg taaaaacgaa
     1021 gtttttgcca taatttccaa atacccaggc agtacggata atatagaaat tagacacatg
     1081 cttctcaact aactcttccc ccatacgctt agtgcgtcca tattctgtct gtggatctgg
     1141 tcggtcatca acttcccact cttgtccaac tggtttctta ccgtcaaaga cctagtccgt
     1201 agaaatataa actagagttg caccatgctt ttcagatgct tttgcgacat tttttgtccc
     1261 catcacattg atggcgaagt ccaactcttt tccttcatcc tctgctgcat caacagcggt
     1321 gtaggctgca caatggtaga ctaaagtcgg tttcacctct tcaaaaactt tctcaaccat
     1381 ttcttcattg gtaatgtcca tctcagccac atctactgcc acgtattctt cattacgttc
     1441 atccaataaa tagcgaagtt ccgttcctaa ttggccattt gcccctgtaa ttaaaatcat
     1501 ctctagacct ttctaatatg taactcttcc caatatagca ataaaaagca gcgatttcct
     1561 gctttttata ctgtaataat ctcctgagtc ttagcataat tggcttcaac agcttctttt
     1621 tctgctttcc accattcttg gttatctgta taccacttga ttgttgcctt gagcccagct
     1681 tcaaagttgg taaattcagg tttccacccc aactcatcac ggagcttgct ggcatcaatc
     1741 gcatagcgaa ggtcatgtcc tgcacggtca gtcacatgat cataggcatc cgtagcttgt
     1801 cccatttcct taaggataag ttccaaaact tccttattgt tcttctcacc atcagcccca
     1861 atcaagtagg tttcaccgat ttgccctttt gtcaagattg tccaaactcc tgaagaatgg
     1921 tcattggtat gaatccagtc acgaacgttc ttaccttcac cgtaaagttt tggcttaatt
     1981 ccacttagga tgttagtaat ctgacgtggg atgaattttt cgatatgttg ataaggaccg
     2041 tagttatttg aacagttgga aatcgttgcc ttgactccaa aagaacgcac ccaggctttg
     2101 acaatcaagt ctgatgcggc cttggttgat gagtacggag agcttgggtt gtattttgtt
     2161 tcagcagtaa atttctcacc tggtccttca ccatgacctg gcaaatcttc tcgtaaaggg
     2221 agatccccat aaacttcatc tgtcgataca tggtggaagc gaatatcata cttacgagca
     2281 gcttctaaaa gagtatagat tccaatgaag ttagtatgaa taaatggcga tggatcattg
     2341 agcgaattat cattgtggct ttccgctgca taatgaacga tagcatctgc ttgagcaacc
     2401 aacttgtcta ccaactccgc atcagcaatg tcaccaacaa ctaactcaac acgattgcct
     2461 aaaatttcct caatattcgc gcggtttcca gcataagtca acttatctag gactgtcacg
     2521 tgaacatctg gaaagttctc gtaaacataa tggacaaagt tagaaccgat aaagccagct
     2581 ccacctgtca cgataatatt tttgtattca gtcatattct ttccttattc caaatcttct
     2641 tttttcaaag gcttcacgtc cttaagtagg ggatgatgtt tgtctgcttc agatacgtct
     2701 gcttcttcca gattttccca ttcaatacca aggcttggat cagcgtagtt cacaaaggca
     2761 tacttgggtt tgagttcaag agcccagtaa tcattgacca gatagctata tgacactgta
     2821 tctgataaaa cttggaagcc attagctacg cctcgaggaa caaagattcc cttgcttgca
     2881 tcaattactg tctgataggt attcccaaag gtttcaccct cgcgtagatc aacccaagaa
     2941 cccagaactt tccctccatc tgctacagag atgtacttat cccaaggctc tgcgtggagg
     3001 cctcgaagga catttttacg tgagaaggat acattgtttt gcaattttcc ttctgcaaag
     3061 aaagactctg gaaatccaag tggaagcact ttttcctttt ggaaattttc tttaaaccag
     3121 ccacgattat ctccatgaac ggggatatca aactccaaca tgcctggaat agcttcaacc
     3181 ttgcgtgccg caagcgtctt accgaaaaaa ttatctgtca tctatgcttc tccaatcaaa
     3241 cggagcagat actgtccgta ttcatttttc ttaagtggtt gggctaaggc caatacatct
     3301 tctcgactga tatagcccat acggtaagca atttcttcta agtttgctac ctgaacattt
     3361 tgcatccgtt gcactgtttc gatgtactgt gaagcctcta gtaaactttc atgagttcca
     3421 gtattcagcc aagcaaagcc acgtcccata agctcaacag acaaatcacc acgatctagg
     3481 taagccttgt ttacatctgt aatttccagt tcaccacgag ggcttggttt aatactcttg
     3541 gcaatttcga caacatcgtt atcatagaaa tacagtcctg tcactgcata gttggagcga
     3601 ggatactccg gtttttcttc tatggaaata gcattcatgt ctgtatcaaa ctcaaccaca
     3661 ccaaaacgct ctggatcctt cacttggtag ccaaaaacag tcgcaccttt ctctttcttg
     3721 gctgcttttt gaagcattgt gctcagacca ggaccatggt agatattgtc gcctaaaatc
     3781 aaggcaacgc tatcgtcaga aataaactct tccccaattg ccaaaccatc tgtacttggt
     3841 tgctctgcat aagaaagttt gatcccaaac tcagatccgt cttgaagaag ctcttgaaat
     3901 cgatgtaaat cctgtggagt ggaaataatc aaaatatccc taatcccagc caacatcaat
     3961 gttgaaagtg ggtagtaaat catcggttta tcataaaccg gcataagttg ttttgacgca
     4021 gcgcgagtca aaggatataa acgtgtcccc gaaccacctg ctagaataat acctttcata
     4081 gtagggtacc tttctttgtt attttagagt caattactat taattgtgta ctgctctaaa
     4141 aagaaaacaa tcatcccatg ttttatatgg ctctataata tttgtagtgg gtaaatccac
     4201 tatagatatt atggagccta ttttattgta gaaaaaaagt cccataagat ctataatgaa
     4261 aagcgaccaa acaactcatt agaaagattc atatgggaca attacatttt atcacaaaac
     4321 tactcgatat caaagaccca aacatcaaga ttctagatat catcaatatg gatacccaca
     4381 aagaaattat cgctaagctg gattatgagg c
//
LOCUS       DAVAZT010000092         4116 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVAZT010000092 DAVAZT010000000
VERSION     DAVAZT010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4116
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.092"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..776
                     /locus_tag="VQT45_002039"
     CDS             <1..776
                     /locus_tag="VQT45_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360292.1"
                     /translation="DYSIVEEKLDWQSKLSKIYPNVEFIKIEKLKLILLCKYRNQIID
                     LEDDKKRLLLLKLLYLTSKQFCYDEFKGAKFGCMSFFSHYQGYMSRLDSLDSDKFVSV
                     KQRIVSSISKLVEQYSDHIINLDRTLVDSLSDTLENQLFDDWDYILSEITTYSELLAK
                     SGLLYNSLDYKIDNVKKEVAKLSDFHQSLFKIEGFSDFFDSWQFQRYRSLVNQVYEIF
                     SMLQVSSVERTVLCGALSTIVFSKSNFNYQAFFEYLKDT"
     gene            805..1713
                     /locus_tag="VQT45_002040"
     CDS             805..1713
                     /locus_tag="VQT45_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360293.1"
                     /translation="MDYVDVILDEYGSVFLIKDHIKLKINNLELYRYFSSFGMSHLQF
                     RKEELPGKLKQFDFEKNKSDSYFSKKSSLIDFIKRNYFYDIKLYSDNPKNPIESWKNK
                     TEKIKIAKSTEILWSEVANFSSISKSPYYCLLYNLKNTENYILIISKTYFSAIQKMVS
                     YNLNNYFELEDVCCKSIVSKRELIENSININKSKMKLLNVCEGSKGYTRRVFKYNNIF
                     VGQLEFHSNIIFSEIALNELSIVKLLDSVESVLSEQLFGKLNWDNLFVVLSDDFNDYL
                     DINESQKYYSNGSLRGLELGIFMGGV"
     gene            1715..3613
                     /locus_tag="VQT45_002041"
     CDS             1715..3613
                     /locus_tag="VQT45_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HET2360294.1"
                     /translation="MRIIEIVDVEDQLLQLLSAHTNIDIRAQELSTLDPDSKVDLIIY
                     LKSRRDIENINNIIIKSPNRNIIVIISAFDIIYALYFPKSTFRPCLNCLLLKLKDNNP
                     EHNLLLFLKYGTLPSKHFNLDNRLKSNLILFNEKLDPKVEEYSIEGVNTTNFTFHFSC
                     SCENSGYDMSERMADILLGEGKKLSPKNYRLKKSEHLFDFTRYLDRNFGFFHHSYDEK
                     ISEYAPLHAVEINVDAGYESGWGRTFMTEAATKSAFLESLERYCNSRNRRYKKLIRGC
                     FSDLSKKYNTLNPVDFCLSNKEYRDSSYKFHDFDSEKNYDWIFGKNITTGKICLLPSQ
                     LVFYKDFSKSEENERFVYETSNGCALGSSIEEAIFYGILEIIERDNFLLTWYLKEEVK
                     QLSWESLPSRLRIINERLKEDNCELKLFNITKEVGIPVIWALYINHNENASIRSFSAA
                     GCHINPLSAIESAIFEVITSVPTFERLIEVRNKESFIEEIQNNFSLIRDIDDHILYHA
                     HADYKNKMPFLFKNNYSEYQNEFDENRIFNTYSHATLTSDLQALIKIIEKKFGDIYVV
                     NISDKVSEKFGLYCVKVLIPGLLNMSFGHSNRRVNIERIKNYVDYRGGNVNSITLNSI
                     NHLPHPFP"
     gene            3637..>4116
                     /locus_tag="VQT45_002042"
     CDS             3637..>4116
                     /locus_tag="VQT45_002042"
                     /inference="COORDINATES: protein motif:HMM:NF025394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="HET2360295.1"
                     /translation="MKRDWKSKHLFYHDVQQFDKLVIYLSKFMDKLVNQNQIEKYFYI
                     RYWEGGPHIRLRYLVRDTQNFETIDSMINKYAYKFWENNPPMKLLNKTDYKKIYNESI
                     DNNGKMDRKLRKNATIENIAYIPEIERYGGEEALIVSEDLFCICSQVSTALLNVVDNY
                     "
BASE COUNT         1539 a          443 c          712 g         1422 t
ORIGIN      
        1 cagattactc aatagtggaa gaaaaattag attggcaaag taaattatct aaaatttatc
       61 cgaatgttga atttataaaa attgaaaaat taaaattgat tttgttgtgt aaatatagaa
      121 atcaaattat tgacttagag gatgataaaa aaagattgtt actattgaaa ttattatatt
      181 tgacttcaaa gcaattttgc tatgatgaat ttaaaggagc gaaatttgga tgtatgtcat
      241 ttttttcaca ttatcaaggt tatatgagca gattagattc actcgactca gataaatttg
      301 tttcggttaa acagaggatt gtttcctcta tttctaaatt agttgagcaa tattcagatc
      361 atattataaa tctggataga actttagttg attctctaag tgataccctt gagaatcagc
      421 tatttgatga ttgggattat atattaagcg aaataactac atatagcgaa ttattagcaa
      481 aatcaggatt gttatataat tcgctagact ataagattga taatgtaaaa aaagaagtgg
      541 ccaagctaag tgactttcac caatctttat ttaaaattga aggattttca gatttttttg
      601 atagttggca atttcaaaga tataggtctc tcgtgaacca agtttatgaa attttttcaa
      661 tgttacaagt aagtagtgta gaaagaactg tgttgtgcgg agctctaagt actattgtct
      721 ttagtaagtc aaattttaac tatcaagctt tttttgagta tctaaaagat acgtagaatt
      781 cgattttaaa ggaggctgaa atatatggat tatgtagatg taatattgga tgagtatggg
      841 agtgtttttc tgataaagga tcacataaaa ctaaaaatta ataatctaga actatatcgg
      901 tattttagta gctttggaat gagtcatctt caatttagaa aagaagagct tccaggaaaa
      961 ttaaagcagt ttgattttga aaaaaataaa agtgacagtt atttttctaa gaaaagtagt
     1021 ctgattgatt ttattaagag aaattatttt tatgatatta agttatattc tgataatccg
     1081 aaaaatccga tagagtcttg gaaaaataag acagaaaaaa ttaagattgc taaaagtaca
     1141 gaaattcttt ggagtgaagt agcaaatttt tcgtcaattt ctaaatctcc ttactattgc
     1201 ttgttatata atttaaagaa tactgaaaat tacatattga taatcagtaa gacatatttt
     1261 tcagccatcc aaaaaatggt ttcgtataat ctaaataatt attttgaatt agaagatgtt
     1321 tgttgtaaaa gcatagtgag caagcgagaa ttgatagaaa attcaattaa tattaacaaa
     1381 agcaaaatga aactgctaaa tgtttgcgaa ggtagtaaag gttacacaag aagagtattt
     1441 aagtacaata atatttttgt gggacaattg gaatttcact ctaacataat cttttcagaa
     1501 attgctttaa atgaattaag tattgttaag cttttagatt ctgttgaaag tgttttatct
     1561 gagcaactat ttggaaaatt aaattgggat aatttatttg ttgttttatc agatgatttt
     1621 aatgattatc tggatataaa tgaatctcaa aaatactact caaatggttc tttgagagga
     1681 ctggagcttg gaatctttat gggaggggtt taaaatgaga ataattgaaa ttgttgatgt
     1741 tgaggaccaa cttttacaac ttttaagtgc acataccaat attgatatta gagcacaaga
     1801 gttatcaaca cttgacccag attcaaaagt tgatttgatc atatacttga aatctcgacg
     1861 tgatattgaa aacataaata atattattat taaatcacct aacaggaata tcattgttat
     1921 aataagtgct tttgatatta tatatgcatt gtattttcca aaatcaacat ttagaccttg
     1981 tttgaactgt ctattattaa aacttaaaga taacaaccct gagcataatc tattattatt
     2041 cctgaaatac ggaacattac ctagtaaaca ttttaatctt gataataggt taaaatcaaa
     2101 tttaatacta tttaatgaga agttagaccc taaggtagag gagtatagta ttgagggggt
     2161 aaatactaca aattttactt tccattttag ttgtagctgt gaaaatagtg gttacgatat
     2221 gtcggaaaga atggcagata ttctacttgg tgaaggaaaa aaattatctc ctaaaaatta
     2281 tcgtttaaaa aagagtgagc atctattcga ttttactaga tatctagata gaaattttgg
     2341 attttttcat cattcatatg atgaaaaaat ctccgaatat gcgcctctcc atgcagtaga
     2401 gattaatgtt gatgctggtt acgagtcagg ctggggaagg acttttatga cagaggctgc
     2461 aacaaaatct gcttttttag agtcattaga gagatactgc aactctagaa atagacgcta
     2521 taaaaaatta attagagggt gtttttctga tttatctaaa aagtacaata cattaaatcc
     2581 tgttgatttt tgtctttcta ataaagaata tagagatagt tcctataaat ttcatgattt
     2641 tgattctgag aaaaattatg attggatatt tggtaaaaat ataactaccg gaaaaatttg
     2701 cttattgccc tcgcaactag tattttataa agactttagt aaaagcgaag aaaatgaaag
     2761 gtttgtttat gaaacatcaa atggatgtgc tttggggagt agtattgagg aagctatttt
     2821 ttatgggatt ttagagatta ttgaaagaga taatttttta cttacatggt atttaaaaga
     2881 agaagtaaaa caattatcat gggaatcttt accatctcgc ctacgtatta ttaatgaaag
     2941 actaaaagaa gataactgtg agctcaaact ttttaatata actaaagaag tgggcatacc
     3001 agtaatttgg gcattgtata taaatcataa tgaaaatgct agtattcgaa gtttttcagc
     3061 tgcaggctgt catattaatc ctttaagtgc aattgaatca gcaatttttg aagtaataac
     3121 ttctgtgcca acttttgaaa gattaattga agttagaaat aaagagtcat ttattgagga
     3181 aattcagaat aatttttctt taatacgaga tattgacgat catatattgt atcatgctca
     3241 tgcggattat aaaaataaaa tgcccttttt atttaaaaat aattatagtg aatatcaaaa
     3301 tgaatttgat gagaatagaa tttttaatac ttattcacat gcaacgctta catcagattt
     3361 acaggcacta ataaaaatta ttgaaaaaaa atttggagat atatatgtag tgaatataag
     3421 tgataaagtt tccgaaaaat ttggacttta ttgtgttaaa gtgttgattc ctggacttct
     3481 taatatgtca tttggacatt caaatcggcg tgtaaatata gagaggataa aaaattatgt
     3541 agattataga gggggaaatg taaatagtat tacattgaat tccataaacc atcttcccca
     3601 tccatttcca taagattata tataaaggaa taataaatga aaagagattg gaaatcaaag
     3661 catttatttt atcatgatgt tcaacaattt gataaattgg taatctattt atcaaaattt
     3721 atggataaat tagttaatca gaatcagatt gaaaaatatt tctatattcg ttattgggaa
     3781 ggggggcctc atattcgatt aagatatttg gtgagggata cacaaaattt tgaaacaatt
     3841 gatagtatga taaataagta tgcttataaa ttttgggaaa ataatcctcc aatgaagtta
     3901 ttaaataaga ccgattataa gaaaatttat aatgagagta ttgataacaa cggaaagatg
     3961 gatagaaaat tgaggaaaaa tgcgactatt gaaaacattg cctatatacc ggaaatagag
     4021 agatatggcg gggaagaagc tctgatagta agcgaagatc tattttgtat ctgtagtcag
     4081 gtttcaactg cgttacttaa tgtggtagat aactat
//
LOCUS       DAVAZT010000093         3939 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVAZT010000093 DAVAZT010000000
VERSION     DAVAZT010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3939
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.093"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            98..1357
                     /locus_tag="VQT45_002043"
     CDS             98..1357
                     /locus_tag="VQT45_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HET2360296.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQIQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    1433..1568
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            1607..2107
                     /locus_tag="VQT45_002044"
     CDS             1607..2107
                     /locus_tag="VQT45_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HET2360297.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            2183..2551
                     /gene="rplL"
                     /locus_tag="VQT45_002045"
     CDS             2183..2551
                     /gene="rplL"
                     /locus_tag="VQT45_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HET2360298.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKTKLEEAGASVTLK"
     gene            2738..2908
                     /locus_tag="VQT45_002046"
     CDS             2738..2908
                     /locus_tag="VQT45_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360299.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            2908..3156
                     /locus_tag="VQT45_002047"
                     /pseudo
     CDS             2908..3156
                     /locus_tag="VQT45_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            3170..3510
                     /locus_tag="VQT45_002048"
                     /pseudo
     CDS             3170..3510
                     /locus_tag="VQT45_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812122.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3503..3883
                     /locus_tag="VQT45_002049"
     CDS             3503..3883
                     /locus_tag="VQT45_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET2360300.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
BASE COUNT         1260 a          700 c          842 g         1137 t
ORIGIN      
        1 agatagaact gacgaagtca gtaaccacac ctacggcaaa gtgaatctga agtggtttga
       61 agagagtaca acttgtcttt tagaaaagga gcctataatg aaagtctttc agcatgtaaa
      121 tatcgtgact tgtgatcaag atttccatgt ttatcttgat ggaatcttag cagtcaagga
      181 ttctcaaatc gtctatgtcg gtcaagataa gccagcgttt ttagagcaag ctgagcagat
      241 tatagactat cagggagctt ggattatgcc tggtttggtc aattgtcaca cccattctgc
      301 aatgacaggt ctgagaggga tccgagatga cagcaatctc catgaatggc tcaatgacta
      361 tatctggcca gcagaatctg agtttactcc cgacatgact accaatgcgg tcaaagaagc
      421 cctgacagag atgctccagt caggaacaac aacctttaac gatatgtata atcccaatgg
      481 tgtggatatc cagcaaattt atcaggtggt gaaaacttcc aagatgcgtt gttatttttc
      541 tccgactctc ttttcttcag agacagaaac aactgctgag actataagca gaactcgatc
      601 catcatagac gaaatcttaa aatataaaaa tccaaatttc aaggttatgg tagcacctca
      661 ttctccgtat agctgcagta gagacttgct ggaagcgagt ttggaaatgg caaaagagct
      721 aaatattccg ctccatgtcc atgtggcgga gaccaaggag gagtcaggaa ttatcctcaa
      781 acgatacggc aaacgccccc ttgcttttct tgaagaactg ggttatttag atcatccgtc
      841 cgtatttgct cacggggtcg aattaaacga gagagaaatt gaacgcttgg catcttctca
      901 agtggctatc gcccacaatc ctatcagtaa cctcaaactg gcatcaggaa ttgctccaat
      961 tatccagatc caaaaagcgg gagtagcagt cggaattgcg actgactcgg ttgcttccaa
     1021 taacaatcta gatatgtttg aggaaggaag gactgcagct cttcttcaga agatgaaaag
     1081 tggggatgcc agccagtttc caatcgaaac agctctcaag gtactgacaa tcgaaggggc
     1141 taaggtcctt ggaatggaaa atcagatagg aagtctggaa gtcggcaagc aagcagattt
     1201 tctggtcatt caaccacaag ggaaaattca tctccaacct caggaaaata tgctgtctca
     1261 cctggtttat gcagttaaat ctagtgatgt agatgatgtt tatatcgccg gagaacaggt
     1321 tgttaagcaa ggtcaagtcc tgacagtaga actttaaaag aaaaatcacg aaaaatttta
     1381 aaaaaagttt gcaaaaatct tgcattcttt ttttgactat gctatactta tatacggttt
     1441 aaaaaaactg cctaagacag taggggagct cgactcataa atatcctacc gaggacaaga
     1501 cgtatcatgt aaaaagaagc gtattgtact ttcgtgtcta ggtttgggcg cgtttttctt
     1561 tttgaaaaat tccccaagca aaataattac ggaggtgaac acactaatga gtgaagcaat
     1621 tattgctaaa aaagcggaac tagttgacgt agtagctgaa aaaatgaaag ctgctgcatc
     1681 tatcgtcgtt gtagacgctc gtggtttgac agttgagcaa gatacagttc ttcgtcgcga
     1741 gcttcgtgga agcgaagttg agtataaagt tattaaaaac tcaatcttgc gtcgtgcagc
     1801 tgaaaaagct ggtcttgaag atcttgcatc tgtatttgtt ggaccatctg cagtagcatt
     1861 ttctaatgaa gatgttatcg caccagcgaa aatcttgaac gacttttcta aaaacgctga
     1921 agcacttgaa attaaaggtg gtgcaatcga aggcgctgtc gcatctaaag aagagattct
     1981 tgcacttgca actcttccaa accgcgaagg acttctttct atgctccttt ctgtacttca
     2041 agcgccagtg cgcaacgttg ctcttgcagt caaagcggtt gcagaaagca aagaagacgc
     2101 ggcttaatct taagctacac agcgtagcct agctacgaaa aaaactatta taaaatttaa
     2161 aacttatttg gaggaaataa caatggcatt gaacattgaa aacattattg ctgaaattaa
     2221 agaagcttca atccttgaat tgaacgacct tgtaaaagct atcgaagaag aatttggtgt
     2281 aactgcagct gctcctgtag ctgttgctgc agctgatgca gctgatgctg gtgctgctaa
     2341 agattcattc gacgttgaat tgacatctgc aggcgacaaa aaagttggcg ttatcaaagt
     2401 tgtacgtgaa atcactggtc ttggtcttaa agaagctaaa gaacttgttg acggtgcacc
     2461 agcacttgtt aaagaaggcg ttgcaactgc agaagctgaa gaaatcaaaa ctaaattgga
     2521 agaagctgga gcttcagtta ctcttaaata atagagtatc gcaatttgat tgcggaatcc
     2581 ctatttacca gtctttgaga gcgataagcg attgatagaa actgataaat tgatttggtt
     2641 tcctgccaaa aattctttgg caggattttt gttttaataa actttcgggg gtagacacta
     2701 gattgtctac cccttttttt gtgtttcgga ggtaattatg caaaaggaag gacagtcatc
     2761 acgtcaattc gtgaagagtc atctcatgac tatcatggga gttgatattg taaaagcaac
     2821 tcagttagtt gatgaaatgg aacaagtagg tttaatccga tttgatgaat ttggaaatgt
     2881 tggaatttta gtcttggagg gacaataatg aagtgtatta ccgctaatca atatcagaca
     2941 tcagagcgtt attataagct ccccaaactt ttatttgaga gtgaacggta taagaatatg
     3001 aaactggagg ttaaggtggt ttactcagtt ttaaaagatc ggttggagtt gtctttgagc
     3061 aaaggttgga ttgatgagga tggggctatt tatttgattt attccaattc aaatttgatg
     3121 gcacttttag gctgttcaaa gtcaaaatta ctctccatgt gagtttgaag tgacattttt
     3181 agatgattac cataaaaaac ataactaccc actattttac gaatcctatc ttcaaaacgt
     3241 tatggaattc cttgaaagtc aagacataaa gaatggggtt gatgcctttg tagatgatca
     3301 tcaaaatctc gtttttgttt tatatggaca aggctatcga gccgagggaa aagagggaat
     3361 acttacaacc caagtaactg taaaagctta tgatgaagac aagaaaccga ttaacttcgc
     3421 aaatttatta gattccttaa tttattagat tccttaatcg tgtcagaata tcaaatggaa
     3481 ccgaatcttt gggaggtctc ccatgattga tctctatcta agtaaaaata gacaaagaaa
     3541 tcaacttctt ttagatttct tccaaaacta tggcatagag gtatcttgtc attcagtttc
     3601 tgaaatgaca aaggacaaat taattgagat gatgagctat tcttcagatt gttttgagtt
     3661 tttatctccc aatttattac gatttaagaa ccgtgacaat ctaagattaa cggatttcgt
     3721 tgagataatt ttaaaaaatc ctgaactaac catcagactt cctcttgcgg tttcaaataa
     3781 gcgagtttat ccaagtctga atttggaaga ggctagagct ctattgccaa gagatacgaa
     3841 acaattgatt tacatggcgc aaacacatta tttatctaac taaaggagaa gcaatatggc
     3901 tgaacgattt tgggagaact tgtccattat tttggctga
//
LOCUS       DAVAZT010000094         3548 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVAZT010000094 DAVAZT010000000
VERSION     DAVAZT010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3548
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.094"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            2..1242
                     /locus_tag="VQT45_002050"
     CDS             join(2..341,341..1242)
                     /locus_tag="VQT45_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET2360301.1"
                     /translation="MVKLIDRYGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSIS
                     LDYALPNQGMLSFWPAQYKKNGYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENE
                     RLRTEVAYLKKFKRVRGKGRSPRARKAETVREMVSGGFRLDFLLETARLARSTYYYQL
                     KQLDGVDKDKEIKTEIQGIDNEHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLT
                     ARIRRKRKYSSYQGEIGKKAENLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPV
                     LDGFNSEIIAYHLSTSPNLEQVKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLE
                     SKGIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNN
                     KRIKVKLKGLSSVQYRTKSFG"
     gene            complement(1477..2085)
                     /locus_tag="VQT45_002051"
     CDS             complement(1477..2085)
                     /locus_tag="VQT45_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001165927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HET2360302.1"
                     /translation="MQIKFIDKVSNLIMLNLLYVASVVTVIAIGSGESALIATLIKIV
                     RHEESYPYRDFANSFFKDYWKNLGAALISNLPILILLFSLFFLPYIPLPIYIISILRH
                     IGVIYIILHLIATTFLIPLIGRYNNTLKNSLHNSIMLAYKHFFIAVLIRIIEIIPVLL
                     FFILQNQLLVWITLMIFILPSITKYANAFLYNFIFSKYEKLN"
     gene            2251..2421
                     /locus_tag="VQT45_002052"
                     /pseudo
     CDS             2251..2421
                     /locus_tag="VQT45_002052"
                     /inference="COORDINATES: protein motif:HMM:NF013577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
     gene            2410..3021
                     /locus_tag="VQT45_002053"
     CDS             2410..3021
                     /locus_tag="VQT45_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET2360303.1"
                     /translation="MTKDILELESQKMSSDTFIDEIKNNYLSIVESTRKLIDGRQIEL
                     AIKLIREANQILMIGVGSSGNAAREFESSLLRIGIISKTVIDTHFQLMHTALLKDNDL
                     IIAFSLSGSTKEVEETLLNAKRKNVKIISITNYSSRNIAKLSDCVLLTSKKESYLEGG
                     SLMAKASQLFIIDVICTRLSLINYEDTICKKEEIASLLSNKVE"
BASE COUNT         1350 a          447 c          630 g         1121 t
ORIGIN      
        1 catggtgaaa ttaattgacc gttatggcat agaaatcgtt aaaaaaggga agaatcgtca
       61 ctattcttct aaattgaaac aagaaatgat ggataaagcc ttactggaag gttgttcaca
      121 aagaagtatt agtcttgatt atgccctccc aaaccaagga atgctttcat tttggccggc
      181 acaatacaag aaaaacgggt atactattgt tgagaaaaca agagggagac cagctaaaat
      241 gggacgtaaa cggaagaaga cttgggaaga aatgacagaa ctagaacgac tccaggagga
      301 gaatgaacgc ttacggactg aggtggccta cctaaaaaag ttaaaagagt tagaggaaag
      361 ggacgaagcc ctagagcgag aaaggcagag acagttagag aaatggtttc aggaggattt
      421 cgactagatt ttcttcttga aacagcacgt ttagctcgct cgacttacta ttatcagttg
      481 aaacaactgg atggggttga taaagataaa gagattaaaa ccgaaattca gggcattgat
      541 aatgaacata aaggcaacta tggctatcgt cgaatccatt tagaactaag gaatcgtggt
      601 tttgtggtca atcataagaa agttcaacgg ttgatgagaa ttcttggttt aacggctcga
      661 attcgccgta aacggaagta ttcttcctac caaggagaga ttggcaagaa agcagagaat
      721 ctcattcaac gccagttcga agcatcgagg ccaatggaaa agtgctatac agatgtgaca
      781 gagtttgcca ttccaaatag cacacagaaa ctctatttat caccagtttt agatggtttt
      841 aacagtgaaa tcattgctta tcatctttct acttcgccaa acttagaaca agtgaagagt
      901 atgttagaac aggcctttac agagaaatac tatgagaata cgattctcca tagtgaccaa
      961 ggctggcaat accaacacga ttcttatcat cggttcctag agagtaaggg aattcaagca
     1021 tccatgtcac gcaagggcaa cagcccagac aacggcatga tggaatcttt ctttggcatt
     1081 ttaaaatccg aaatgtttta tggctatgag aagaacttta gatctttaga aaaccttgaa
     1141 caagctattg tggactacat tgattactac aacaacaaac gaattaaggt aaaactaaaa
     1201 ggacttagtt ctgtgcagta cagaactaaa tcctttggat aaattatttg tctaattttt
     1261 tggggtcagt acagtattaa ataccatgat cttatgcgtt ttataataaa aaatctgttc
     1321 ttgttttatt tttagaaaat ttactaaaga ctaaaaatat tatgaataat ttaaaaaata
     1381 gtcaggttat atagtttttt gaaattaaaa ttattttatc gttgaaatta gttaaaaatt
     1441 tttataaaat caagatgcaa ggctatgaga tgttctctag tttaattttt catacttcga
     1501 gaatataaag ttatataaaa atgcattagc atattttgtt attgagggaa gtataaaaat
     1561 cattaaagtt atccaaacta gtaattgatt ctgtaatata aagaagagta gaactgggat
     1621 aatttcaata attctaataa gaacggcaat aaaaaaatgt ttataggcta acatgattga
     1681 attgtgtaga gaatttttta aagtgttatt atatctaccg attaaaggaa ttagaaatgt
     1741 tgttgctatt aaatgaagta tgatatatat tactccaata tgtcgtaaga tagaaatgat
     1801 atatataggt aatggtatgt agggtaggaa gaacaaactg aataataaga ttaaaattgg
     1861 taaattagat attaatgctg ctcctaaatt tttccaataa tctttaaaaa aactgtttgc
     1921 gaagtctcta tagggatagg attcctcgtg tcgtacaatt tttattagag ttgctattag
     1981 ggcactttca cctgatccga tagcaataac tgttactact gacgctacat agagtagatt
     2041 taacattata agatttgaaa ctttatcaat aaattttatc tgcatcttta actcctgctg
     2101 tttttatact tataatatca catcatttga gtttcatcaa ctttgaatac attaagaaag
     2161 aatataacta tgaggaaagg aaaaaattat tatgaataaa tccaaaaaat ataaagaaag
     2221 aattcattat gaatacgata atcttactaa atcagagaaa aaattgctga ctatatttta
     2281 gttagagata gtgaaatagt ttatgaaacg tcttcagaaa ttgttagtaa agtaaaagtt
     2341 ggagagggaa ctcttaatcg attttgcaaa aagattggat actctggttt tcaggaacta
     2401 aaattaaaaa tgacgaaaga tatattagag ttagaatctc aaaaaatgag tagtgacaca
     2461 tttattgatg aaataaaaaa taattattta tctattgtgg aaagtacaag aaaattaatt
     2521 gatggtagac aaatagaatt agctataaaa ttaataagag aagcaaacca gattttaatg
     2581 attggtgtgg gttctagtgg aaatgcggct agagaatttg agagtagttt gttaagaatt
     2641 ggaataataa gtaagacggt aattgatacc cattttcaac tcatgcatac tgcgttattg
     2701 aaagataatg atttgataat agcgtttagt ttatctggtt ccacaaaaga agttgaggaa
     2761 actttattaa acgcaaaaag aaaaaatgtt aaaattattt caataacaaa ttattcgtcc
     2821 agaaatatag caaaattatc tgactgcgtt cttttgacat caaaaaaaga atcttattta
     2881 gagggtggta gtttaatggc taaggcttct caactattca taattgatgt aatatgcact
     2941 agactctctt taataaatta tgaagatact atatgtaaaa aagaagagat tgcttctttg
     3001 ctgtcaaata aagtggaata aatcaataat ttttaaattt taataaaaat tttttaaaat
     3061 aaattaaaaa acgatcctaa aagggtcgtt tttttgctaa agttttaaaa ataaacaata
     3121 attaagatta tagtgcgttg aatctatatt aggacataac aattcttaaa tcattgttag
     3181 aaattagttt gaattttcca atcaatttgt tcgattttta catcattgca ttatatcacg
     3241 tgactattaa ccttgttttc tcctaaaatt gattttcttc ttttcttatc ttgtccactc
     3301 gaaacaagta ttgtaagaat ttgattattt ttgaaagtac ttttaatata tttgagatag
     3361 ttaaaaaaga tttgaaacta aattccaaat tagaaaaaga cttgaaatgc taaaaaaaaa
     3421 aagtatactc taattgaaaa cggtaacaaa actaatttag agaatgaaat atagagtatt
     3481 tctctcttaa aagtttttgg tgaaacgaga tgtagaaagg agatttagcc aaagagtcta
     3541 ttagtgct
//
LOCUS       DAVAZT010000095         3287 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVAZT010000095 DAVAZT010000000
VERSION     DAVAZT010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3287
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.095"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..327
                     /locus_tag="VQT45_002054"
     CDS             <1..327
                     /locus_tag="VQT45_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2360304.1"
                     /translation="VKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMTSS
                     TNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLGLK
                     NKKEEN"
     gene            494..1192
                     /locus_tag="VQT45_002055"
     CDS             494..1192
                     /locus_tag="VQT45_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2360305.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            1189..2241
                     /locus_tag="VQT45_002056"
     CDS             1189..2241
                     /locus_tag="VQT45_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET2360306.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVTKLEKGQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            2436..3047
                     /gene="rpsD"
                     /locus_tag="VQT45_002057"
     CDS             2436..3047
                     /gene="rpsD"
                     /locus_tag="VQT45_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HET2360307.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
BASE COUNT          995 a          631 c          740 g          921 t
ORIGIN      
        1 gttaaagaaa catcagacac agcaaatggt tcattatcac cttctaactc tggttctggc
       61 gtgactccga tgaatcacaa tcatgctaca ggtactacag atagcatgcc tgctgacacc
      121 atgacaagtt ctaccaacac gatggcaggt gaaaacatgg ctgcttctgc taacaagatg
      181 tctgatacga tgatgtcaga ggataaagct atgctaccaa atactggtga gactcaaaca
      241 tcaatggcaa gtattggttt ccttgggctt gcgcttgcag gtttactcgg tggtctaggt
      301 ttgaaaaaca aaaaagaaga aaactaatca gctaaggaaa taaatgatgg atagtgggct
      361 gactaagatt agtttaacaa ctcaatcagc aatcaggact ttctttcaat agcagattaa
      421 aatcatcgta aaacaataaa aatagtgtta tacttaaagc agtatagcac tgtttttatc
      481 aaaggagaga cagatgggaa agacaatttt actcgttgac gacgaggtag aaatcacaga
      541 tattcatcag agatacttaa ttcaggcagg ttatcaggtc ttggtagccc atgatggact
      601 ggaagcgcta gagctgttca agaaaaaacc gattgatttg attatcacag atgttatgat
      661 gcctcggatg gatggttatg atttaatcag tgaggttcaa tacttatcac cagagcagcc
      721 tttcctattt attactgcta agaccagtga acaggacaag atttacggcc tgagcttggg
      781 agcagatgat tttattgcta agccttttag cccacgtgag ctggttttgc gtgtccacaa
      841 tattttgcgc cgccttcatc gtgggggcga aacagagctg atttcccttg gcaatctaaa
      901 aatgaatcat agtagtcatg aagttcaaat aggagaagaa atgctggatt taactgttaa
      961 atcatttgaa ttgctgtgga ttttagctag caatccagag cgagttttct ccaagacaga
     1021 cctctatgaa aagatctgga aagaagacta cgtggatgac accaatacct tgaatgtgca
     1081 tatccatgct cttcgacagg agctggcaaa atatagtagt gaccaaacgc ccactattaa
     1141 gacagtttgg gggttgggat ataagataga gaaaccgaga ggacaaacat gaaactaaaa
     1201 agttatattt tggttggata tattatttca accctcttaa ccattttggt tgttttttgg
     1261 gctgttcaaa aaatgctgat tgcgaaaggc gagatttact ttttgcttgg gatgaccatc
     1321 gttgccagcc ttgtcggtgc tgggattagt ctctttctcc tattgccagt ctttacgtcg
     1381 ttgggcaaac tcaaggagca tgccaagcgg gtagcggcca aggattttcc ttcaaatttg
     1441 gaggttcaag gtcctgtaga atttcagcaa ttagggcaaa cttttaatga gatgtcccat
     1501 gatttgcagg taagctttga ttccttggaa gaaagcgaac gagaaaaggg cttgatgatt
     1561 gcccagttgt cgcatgatat taagacccct atcacttcga tccaagcgac ggtagaaggg
     1621 attttggatg ggattatcaa ggagtcggag caagctcatt atctagcaac cattggacgc
     1681 cagacggaga ggctcaataa actggttgag gagttgaatt ttttgaccct aaacacagct
     1741 agaaatcagg tggaaactac cagtaaagac agtatttttc tggacaagct cttaattgag
     1801 tgcatgagtg aatttcagtt tttgattgag caggagagaa gagatgtcca cttgcaggta
     1861 atcccagagt ctgcccggat tgagggagat tatgctaagc tttctcgtat cttggtgaat
     1921 ctggtcgata acgcttttaa atattctgct ccaggaacca agctggaagt ggtgactaag
     1981 ctggagaagg gccagctttc aatcagtgtg accgatgaag ggcagggcat tgccccagag
     2041 gatttggaaa atattttcaa acgcctttat cgtgtcgaaa cttcgcgtaa catgaagaca
     2101 ggtggtcatg gattaggact tgcgattgcg cgtgaattgg cccatcaatt gggtggggaa
     2161 atcacagtca gcagccagta cggtctagga agtaccttta ccctcgttct caatctctct
     2221 ggtagtgaaa ataaagccta aaaccccttt acaaatccag ctattcatgg taaaatggat
     2281 tttgtgtgaa atatcagcag gaaagcatga agctcgtcaa caggtgtctt atgacaagta
     2341 accttggctg tttaggcgaa gggcatctgc acgaatcagg gctttctaag tgactatttc
     2401 caccgaaata ttatttatat caggaggaca ttcatatgtc acgttataca ggaccatctt
     2461 ggaaacaagc tcgtcgcctt ggcctttcac ttacaggtac aggtaaagaa ttggcacgtc
     2521 gtaactacgt accaggacaa cacggaccaa acaaccgttc taaattgtca gaatacggtt
     2581 tgcaattggc tgaaaaacaa aaacttcgtt tcacttacgg tgtaggtgaa aaacaattcc
     2641 gtaacttgtt cgtacaagct acaaaaatca aaggcggaat cctaggtttc aactttatgc
     2701 ttcttttgga acgtcgtttg gataacgttg tttaccgtct tggtctcgcg actactcgtc
     2761 gtcaagctcg tcaattcgta aaccacggtc acatccttgt tgacgggaaa cgcgttgata
     2821 tcccatcata ccgcgtaact ccaggtcaag tgatctcagt tcgtgaaaaa tcattgaaag
     2881 ttccagcaat ccttgaagca gtagaagcta ctcttggacg tccagcattc gtatcattcg
     2941 acgctgaaaa attggaaggt tcattgactc gcttgccaga acgcgacgaa atcaacccag
     3001 aaatcaacga agcacttgtc gttgaattct acaacaagat gttgtaatat tttattgaat
     3061 aagacaggct ttgaggcctt gatattaagc actttgggac gttctccctt agtgcttttt
     3121 tgatttctct tagtatccag ctataatcgt ttagacataa ctagaccgat atagtccaaa
     3181 gtgatatagt aaaatgaacc aaaaatagta cacaatgtgg tataatcctt ttatggcata
     3241 ttcaatagat tttcgtaaaa aaattctctc ttattgtgag cgaacag
//
LOCUS       DAVAZT010000096         2694 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVAZT010000096 DAVAZT010000000
VERSION     DAVAZT010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2694
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.096"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            276..590
                     /locus_tag="VQT45_002058"
     CDS             276..590
                     /locus_tag="VQT45_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360308.1"
                     /translation="MWVLGFILFLIFFYSNDSKKIKKLEKKIKRLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            600..806
                     /locus_tag="VQT45_002059"
     CDS             600..806
                     /locus_tag="VQT45_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2360309.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            806..1003
                     /locus_tag="VQT45_002060"
     CDS             806..1003
                     /locus_tag="VQT45_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360310.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            1059..1739
                     /locus_tag="VQT45_002061"
     CDS             1059..1739
                     /locus_tag="VQT45_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HET2360311.1"
                     /translation="MGMFVGMFKARVESHEIILDVKALMPWISAICLLIGFISMFLTF
                     NFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAFNITGVVIPLAIFISLSEV
                     IILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLEFFATPKDVLNYINSYDEG
                     ERQANLEQSFRILFQLHQYVLPALYIFLIILSFLTGEIQLLAFLLVGAIHVYINVMQL
                     PMVKRYFK"
     gene            1751..2392
                     /locus_tag="VQT45_002062"
     CDS             1751..2392
                     /locus_tag="VQT45_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2360312.1"
                     /translation="MKLLKNLGWFLLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            2410..2640
                     /locus_tag="VQT45_002063"
     CDS             2410..2640
                     /locus_tag="VQT45_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360313.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
BASE COUNT          791 a          442 c          559 g          902 t
ORIGIN      
        1 gatagaactg acgaagtcag ctcaaaacat ggttttgagg ttgtagatga aactgacgaa
       61 gtcagtaacc atacctacgg caaggtgaag ctgacgtggt ttgaagagat tttagaagag
      121 tattaatgat agataaagtg gtcaggaacc tactcctgac ctttttcttt tgcaaaatga
      181 caaaaatcat aatttttttg acaactatac ttgtcaaaaa gaaaaagatg tgttacaatg
      241 taagcaagtt aagagaaaag aagaaaggag ctatgatgtg ggtactaggg tttatactat
      301 ttctgatttt cttttattct aatgattcta aaaaaatcaa gaaactagag aagaaaatca
      361 aaagacttga gcgaaaagag aaaggaaatg cagaaatgtc gagattatta caagaaatga
      421 ttggaaagga accaattata acgggagtgt atattgggcc agataactgg gaagttgtgg
      481 atgttgatga ggaatgggta aagctacgac gtgtagataa tacgggaaaa gaaaaattca
      541 agttgcaacg tattgaggat atccaaaccg ttgaatttga cggagagtag gtgtgtaaca
      601 tgcaactaaa aaatcgtcta aaagagcttc gagctcgcga tggtctcaat caaaccgacc
      661 tagccaaact ggcaggggtt tccagacaga ccattagcct actagaacgg gatgagtaca
      721 ccccatccat tatcattgcc ctgaaaatat ctcaaatttt caacgaaaca gtcgaatcgg
      781 tatttcgttt ggaggaggac gagtgatgaa caagtataaa gtgatttatt atgtagtggt
      841 catagcttta ttagtcagcg tatttctact gattgggatg gacctaagct ggtttaatcc
      901 ctatcaaagc gaccaatttg tttgggtcta ctttgctctc atcccagtaa ttgaatggat
      961 tgaaaagaaa tccaaaaatc tagcaagtga aaaaggagaa tgaatatgaa aaagaaacgt
     1021 agattgttat ttttgatgtc tattgtcttg gggggttctt gggcatgttt gtagggatgt
     1081 ttaaggcacg tgtcgaatcc cacgaaatta ttttagatgt aaaagccttg atgccatgga
     1141 tatcagctat ttgtttactg ataggtttca ttagtatgtt tttgactttc aatttcttaa
     1201 agaaaagcag aaaatttcat tccttgtatc aagaggaaat ggatgacgat ctgaatgaaa
     1261 cctattatgt gcaaatgtat cggaatcttg agtttggaac cattgctttt aatattacag
     1321 gtgtagtgat tccattggct atttttattt cattaagtga ggtgattata ttgcatacaa
     1381 accctcaaac atttttcctt tctttcttac tctttgtggt attcttagtc gctcaaaaat
     1441 ctctttttaa aaccattgcg attgttcgtc agtttgattt ggaatttttc gctacaccaa
     1501 aggatgtctt gaactatata aattcttatg atgaagggga gcgtcaggct aatttggaac
     1561 agagttttcg aattttattc caattacacc aatatgtctt accagcctta tatatttttc
     1621 ttattatcct ttctttcttg acaggagaga ttcagttact agctttcttg cttgtaggag
     1681 ccatccatgt ttatatcaat gtgatgcagt tacctatggt aaaacgttat ttcaaataaa
     1741 ggagttatct atgaaattac ttaaaaacct tggctggttt cttctagccc ttctatcctt
     1801 tttctttatc tatggcttta ttcaggggct cgcgactgcg tcgcttgctt taggcgcttc
     1861 accctatgct gttactctac tctatgtggt cttggctgga gtatatgtgt acggcattta
     1921 caaatggtat cagaaagctc ctgtttatat tgagaagagc ggctttaacc gatttatttg
     1981 gcttcctgcc ttggtttggt tcttatctct ggtcgttcaa ttcttcttgc cagatgatcc
     2041 ttcagtaaat cagcaaatag cgacagactt gaccttgtct caaccacttt tctcattctt
     2101 tgctgtggtt atttttgctc ctttgacgga agagattgtt tttagaggga tgttagcacg
     2161 ctatctcttt cctaagcagg acaatagtaa acgaaccctg atttttcttc tggtatctag
     2221 tcttctattt gccttgattc attttccagg tgatgtgcaa caattttttg tctattttag
     2281 ccttggtttt agtttgggtt tggcttacat tagcagaaaa ggtctggtct acagtatttc
     2341 tcttcacgct ttgaataatt tagtcggctt tttgatgatt ctcatgctat aatagagtca
     2401 ggaggtcaca tgaaacgagt aattttatta gcagtgattc aggcagtcgt tctatttttc
     2461 atcattggag cgctagctta tgccttcaaa ggcgatttct tctataacta tctagcagtt
     2521 gtctttgctc ctattgcagg tgtactgcgt tttgggacgg cttacataac ggaaattgtc
     2581 ttgcctcgaa aggcagccga aatcgctgaa aagcgtaaag caggcaaaaa ttcaaaataa
     2641 aagagtccgg tgaagttcat cggatttttg tattatactc aatgaaaatc aaag
//
LOCUS       DAVAZT010000097         2609 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVAZT010000097 DAVAZT010000000
VERSION     DAVAZT010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2609
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.097"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..661
                     /locus_tag="VQT45_002064"
     CDS             <1..661
                     /locus_tag="VQT45_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2360314.1"
                     /translation="FYLNKGKVYGFVGPNGAGKTTIIKMILGILKPDSGKITIFNQTV
                     EQNSKNILSRIGLVLGPSFYGHLDAYKNLKLIANMKGLSLDTERLNEYLSMVGLKDVK
                     KKKVKNFSMGMKQRLSIAASLLGSPEILIWDEPINGLDPQGVIEIRSLIRFLQEKKGI
                     TFLISSHILSELDKVISDIIIINYGKVEFFGSCHYLLQKYNCRNLEEAYLACLAGGEY
                     D"
     gene            654..1391
                     /locus_tag="VQT45_002065"
     CDS             654..1391
                     /locus_tag="VQT45_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2360315.1"
                     /translation="MIKLEFLKQKKSILWFVLIFPIILNALLYIDLTFRYRGYLLVHQ
                     NELALSNWQLIFKEQTIFYFSELFYLVLSLIIYEVFAVEFKNDAWLTVISLPFRNKYT
                     INSKLLITVVYTFTFWLSDYISLYVIGKAIDNSLEIGLIFFLKTFTIQLISSLMIMLL
                     YFLTLVLIRKISGIIPIGIIMMILTISIYYNDYNFKIYLPFTYLSHAFRVTESQFYMI
                     LLSNIIIIVLFYILIRKLNERSFEMKL"
     gene            1404..2129
                     /locus_tag="VQT45_002066"
     CDS             1404..2129
                     /locus_tag="VQT45_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360316.1"
                     /translation="MKLLKNELIKSKIFLFIIVDICIQILVILAIKTYILDISAPYSE
                     LDYNKYWYVLHALIYMPMIFPIQILYQNLREALIEDNNNGWNIMVINTNNLVKIIYIK
                     VTINIVRCFICYFVYTIFSLIQLGGMGTDMLLTNIIFPNIIFPNIMSFLLFLPIAIFM
                     QICCIRFDSILAKALPNILLILIVLITFQSDWNIFIPATYYYTEIQSTTNLGIKLLVC
                     IWIMGFEFSLLPKLIKLKEQNLV"
BASE COUNT          908 a          317 c          388 g          996 t
ORIGIN      
        1 attttattta aataagggaa aagtatatgg ttttgttgga ccaaatgggg ctggaaaaac
       61 tacaattatc aaaatgattc tagggatttt aaaaccagat tctgggaaaa taactatttt
      121 taatcaaacc gtagaacaga attccaaaaa tatattatct aggataggat tagttttggg
      181 accttcattt tatggtcatc ttgatgctta taaaaatttg aagttaatag caaatatgaa
      241 agggcttagt ttagatactg aaagacttaa tgaatatcta tcaatggtag gattaaaaga
      301 tgttaaaaag aaaaaagtga aaaatttttc aatgggcatg aaacaacgtc taagtatagc
      361 tgcatcattg ttaggtagtc cagaaatatt aatttgggat gaaccaatca atggacttga
      421 tccacagggt gtaattgaaa ttagaagttt aatccgtttt ctacaggaga aaaaaggtat
      481 tacattttta atatcaagtc atattcttag tgaactggat aaagtgatat ctgatattat
      541 aattataaat tatgggaaag ttgaattttt tggttcttgc cactaccttt tacaaaagta
      601 taattgtcga aatctggaag aagcctactt agcttgttta gctggaggtg aatatgatta
      661 aattagagtt tctaaagcag aaaaaaagca tcttatggtt tgttcttatt tttccaataa
      721 ttctgaatgc tttgttatat atagacttaa cttttaggta tcgaggttat ttattggtgc
      781 atcaaaatga acttgcttta tctaattggc agttaatttt taaagaacaa acaatatttt
      841 atttttctga actattttat ttagttctat ctttaataat ttacgaagtg tttgcagtag
      901 aatttaaaaa tgatgcatgg ttaaccgtaa tttcattgcc atttagaaac aagtacacaa
      961 taaattctaa attactcatt acagtggttt acacatttac tttttggttg tctgattata
     1021 ttagcttata cgttattggg aaggctattg ataacagttt agagattggt ttgattttct
     1081 ttttaaaaac atttaccatt caattaattt cctcgttgat gataatgtta ttatattttc
     1141 taactttagt acttataagg aaaatttctg gaataatacc aattggtatt ataatgatga
     1201 ttttaacaat tagcatatac tacaacgatt ataattttaa gatttactta ccatttactt
     1261 atctttctca tgcttttaga gtgactgaaa gtcaatttta tatgatttta ctatctaata
     1321 taataatcat cgtacttttt tatatattaa ttcgtaaatt gaacgaaaga agttttgaga
     1381 tgaaacttta ataggtaata aaaatgaagt tacttaaaaa tgaattgatt aagagtaaaa
     1441 tatttttatt tattattgtt gacatctgta ttcagattct agtcattcta gctataaaaa
     1501 catatatttt agatatttcg gcaccatact cagagcttga ttataataag tattggtatg
     1561 ttttacacgc tttaatatat atgccaatga tttttcctat acaaattttg tatcaaaatc
     1621 taagagaggc attgattgaa gataataata atggttggaa tatcatggtg attaacacta
     1681 ataatctcgt gaaaatcatc tatataaaag taacgataaa tatcgtgaga tgttttattt
     1741 gttattttgt ttatacaatt ttttctttaa ttcaattagg tggtatggga actgatatgt
     1801 tattaaccaa tataatattt cccaatataa tatttcccaa tataatgtca tttctgttat
     1861 ttttacctat agctatcttt atgcaaattt gctgtataag atttgattcc attttagcaa
     1921 aggccttacc taatattttg ctgatactta ttgttttaat cacgtttcag agtgattgga
     1981 atatatttat acctgcaact tattattata cagaaattca gtcaactaca aacttaggta
     2041 ttaaattatt agtttgtatc tggattatgg gatttgaatt ttcccttctt ccaaaactaa
     2101 taaaattgaa agaacaaaat ctagtttaaa tgttgctcga aaattaaata attgaatacg
     2161 attaacaatg aaacaataca acgtgagtca tgacttcaaa gtaattgatt ttatgattct
     2221 ggtttcttac gcttaattaa gcaagttgta ttcactttat caaattgtta ttactctaaa
     2281 aagcgtctaa cagctataga gtgtctgttt gcttctcttt acttttattt taaataattc
     2341 attaaccttc cgtaagtgcc caataataag gtgtgttgaa gaagtctgag ataaaatagt
     2401 tctcagtcac aaaaaaagct atagattccc attggtgaac agctccctgt caagtagaca
     2461 gtaaaataat ataaaatctt aagcgacctg attcctgaat tccagtggag tcaggttgtt
     2521 ttttaaccgt ctttcttaat attgtctcac ctataataga tatgcttatg agatatgttt
     2581 aataaattaa ttttagttca aaatgtcca
//
LOCUS       DAVAZT010000098         2508 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVAZT010000098 DAVAZT010000000
VERSION     DAVAZT010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2508
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.098"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..2253
                     /gene="phtA"
                     /locus_tag="VQT45_002067"
     CDS             <1..2253
                     /gene="phtA"
                     /locus_tag="VQT45_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HET2360317.1"
                     /translation="EQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEELLMKDPNY
                     KLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHSQHREGGTP
                     RNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNELSASELA
                     AAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSNTNSQASQS
                     NDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGDHYHFIPYSQMSE
                     LEERIARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSNSSLVSQLV
                     RKVGEGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKENVAPRDQE
                     FYDKAYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDLLAFLAPIT
                     HPERLGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYVTPHMGHSH
                     WIGKDSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVKGEKRIPLV
                     RLPYMVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLFATIKYYVE
                     HPDERPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVPQVETEKVE
                     AQLKEAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEKLLALLKGSN
                     PSSVSKEKIN"
     gene            2411..>2508
                     /locus_tag="VQT45_002068"
     CDS             2411..>2508
                     /locus_tag="VQT45_002068"
                     /inference="COORDINATES: protein motif:HMM:TIGR01363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2360318.1"
                     /translation="MKINKKYLAGSVATLVLSVCAYELGLHQAQTV"
BASE COUNT          881 a          467 c          497 g          663 t
ORIGIN      
        1 gagcaaatcg tcatcaagat aacagaccaa ggctatgtca cttcacatgg cgaccactat
       61 cattattaca atggtaaggt tccttatgat gcgattttca gtgaagaatt actcatgaaa
      121 gatccaaact ataagctaaa agatgaggat attgttaatg aggtcaaggg tggatatgtt
      181 atcaaggtag atggaaaata ctatgtttac cttaaggatg ctgcccacgc ggataacgtc
      241 cgtacaaaag aggaaatcaa tcgacaaaaa caagaacata gtcaacatcg tgaaggtggg
      301 actccaagaa acgatggtgc tgttgccttg gcacgttcgc aaggacgcta tactacagat
      361 gatggttata tctttaatgc ttctgatatc atagaggata ctggtgatgc ttatatcgtt
      421 cctcatggag atcattacca ttacattcct aagaatgagt tatcagctag cgagttggct
      481 gctgcagaag ccttcctatc tggtcgggga aatctgtcaa attcaagaac ctatcgccga
      541 caaaatagcg ataacacttc aagaacaaac tgggtacctt ctgtaagcaa tccaggaact
      601 acaaatacta acacaagcaa caacagcaac actaacagtc aagcaagtca aagtaatgac
      661 attgatagtc tcttgaaaca gctctacaaa ctgcctttga gtcaacgaca tgtagaatct
      721 gatggccttg ttttcgaccc agcgcaaatc acaagtcgaa cagctagagg tgttgcagtg
      781 ccacacggag atcattacca cttcatccct tactctcaaa tgtctgaatt ggaagaacga
      841 atcgctcgta ttattcccct tcgttatcgt tcaaaccatt gggtaccaga ttcaaggcca
      901 gaacaaccaa gtccacaacc gactccggaa cctagtccag gcccgcaacc tgcaccaaat
      961 cttaaaatag actcaaattc ttctttggtt agtcagctgg tacgaaaagt tggggaagga
     1021 tatgtattcg aagaaaaggg catctctcgt tatgtctttg cgaaagattt accatctgaa
     1081 actgttaaaa atcttgaaag taagttatca aaacaagaga gtgtttcaca cactttaact
     1141 gctaaaaaag aaaatgttgc tcctcgtgac caagaatttt atgataaagc atataatctg
     1201 ttaactgagg ctcataaagc cttgtttgaa aataagggtc gtaattctga tttccaagcc
     1261 ttagacaaat tattagaacg cttgaatgat gaatcgacta ataaagaaaa attggtagat
     1321 gatttattgg cattcctagc accaattacc catccagagc gacttggcaa gccaaattct
     1381 caaattgagt atactgaaga cgaagttcgt attgctcaat tagctgataa gtatacaacg
     1441 tcagatggtt acatttttga tgaacatgat ataatcagtg atgaaggaga tgcatatgta
     1501 acgcctcata tgggccatag tcactggatt ggaaaagata gcctttctga taaggaaaaa
     1561 gttgcagctc aagcctatac taaagaaaaa ggtatcctac ctccatctcc agacgcagat
     1621 gttaaagcaa atccaactgg agatagtgca gcagctattt acaatcgtgt gaaaggggaa
     1681 aaacgaattc cactcgttcg acttccatat atggttgagc atacagttga ggttaaaaac
     1741 ggtaatttga ttattcctca taaggatcat taccataata ttaaatttgc ttggtttgat
     1801 gatcacacat acaaagctcc aaatggctat accttggaag atttgtttgc gacgattaag
     1861 tactacgtag aacaccctga cgaacgtcca cattctaatg atggatgggg caatgccagt
     1921 gagcatgtgt taggcaagaa agaccacagt gaagatccaa ataagaactt caaagcggat
     1981 gaagagccag tagaggaaac acctgctgag ccagaagtcc ctcaagtaga gactgaaaaa
     2041 gtagaagccc aactcaaaga agcagaagtt ttgcttgcga aagtaacgga ttctagtctg
     2101 aaagccaatg caacagaaac tctagctggt ttacgaaata atttgactct tcaaattatg
     2161 gataacaata gtatcatggc agaagcagaa aaattacttg cgttgttaaa aggaagtaat
     2221 ccttcatctg taagtaagga aaaaataaac taatgaaaaa tgaaagtctc gataaagagg
     2281 ctttcatttt tattatgtat atatgtaaaa ttcttgacaa gcaatattaa aaagagtaaa
     2341 ctattaacta gttaattaac cggtttgtta ctttatagtg aatcaaatat acttaagaaa
     2401 agaggaaaga atgaaaatca ataaaaaata tctagctggg tcagtagcta cacttgtttt
     2461 aagtgtctgt gcttatgaac taggtttgca tcaagctcaa actgtaaa
//
LOCUS       DAVAZT010000099         2396 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVAZT010000099 DAVAZT010000000
VERSION     DAVAZT010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2396
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.099"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(30..426)
                     /locus_tag="VQT45_002069"
                     /pseudo
     CDS             complement(30..426)
                     /locus_tag="VQT45_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(371..553)
                     /locus_tag="VQT45_002070"
     CDS             complement(371..553)
                     /locus_tag="VQT45_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET2360319.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            910..>2396
                     /gene="pcpA"
                     /locus_tag="VQT45_002071"
     CDS             910..>2396
                     /gene="pcpA"
                     /locus_tag="VQT45_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HET2360320.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDGA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKGLWYYLNESGSKATGWVKDKGLWYYL"
BASE COUNT          837 a          359 c          396 g          804 t
ORIGIN      
        1 agccttcata gcgtggcatt tctttttact tccgtcacat caatcattac cgtgtcctca
       61 gaactgagag gagttcttga aatcgtaaca ccacctttga acaagagtta cttcaaccca
      121 ttagctccga cggattaagt tgctttcgtg aataccaaaa tcagccgcaa tttcttcata
      181 agtgcggtat tctcgcacat attgaagagt ggccataaga aggtcttcta ggcttaattt
      241 aggttttcgt ccaccttttg tgtgtttaag ttgataagct gtttttaaca cagctaacat
      301 ctcttcaaaa gtggtgcgct gaacaccaac aagacgctta aatcgtgcat cggttagttg
      361 tttacttgct tcataatttc gcagggagtc tattgactct ttggtaggtg tcaatgtttt
      421 tttcatctat cccgagaatt attttcccgc catttgtatt tgcaaatgct gagtaggttt
      481 cccagaaaga ctctggaaga ttgtttttag cttttttgta ttctaaatca accccttcaa
      541 attttaagtc catatttttc ctttacatct gttttttgtg gttctggtat ttgttcaagt
      601 tgagtgataa tatagcgaat tgaatttcga gagtttttac tcagttaatt tcttttttaa
      661 cccactttaa tttctttttt aacccacttt aatttctttt ttaacacggg ttaaaaaaga
      721 aattaaagtg ggttaatttt tcttgactta aaatttaaaa atgatatact gtgtttatgg
      781 agagatgaca atttataaaa tgtactactc tattctacta gataatgatt gaataaaact
      841 ttttataaca acggctagca aagttataat tttatatcta ttagaaaata aatatgtaag
      901 gaaatttaaa tgaaaaaaac tacaatatta tcattaacta cagctgcggt tattttagca
      961 gcatatgtcc ctaatgaacc aatcctagca gatactccta gttcggaagt aatcaaagag
     1021 actaaagttg gaagtattat tcaacaaaat aatatcaaat ataaggttct aactgtagaa
     1081 ggtaacatag gaactgttca agtgggtaat ggagttactc ctgtagagtt tgaagctggt
     1141 caagatggaa aaccattcac gattcctaca aaaatcacag taggtgataa agtatttacc
     1201 gttactgaag tagctagtca agcttttagt tattatccag atgaaacagg tagaattgtc
     1261 tactatccta gctctattac tatcccatca agcataaaaa aaatacaaaa aaaaggcttc
     1321 catggaagta aagctaaaac tattattttt gacaaaggca gtcagctgga gaaaattgaa
     1381 gatggagctt ttgatttttc tgaattagaa gagattgaat tgcctgcatc tctagaatat
     1441 attggaacaa gtgcattttc ttttagtcaa aaattgaaaa agctaacctt ttcctcaagt
     1501 tcaaaattag aattaatatc acatgaggct tttgctaatt tatcaaattt agagaaacta
     1561 acattaccaa aatcggttaa aacattagga agtaatctat ttagactcac tactagctta
     1621 aaacatgttg atgttgaaga aggaaatgaa tcgtttgcct cagttgatgg tgttttgttt
     1681 tcaaaagata aaacccaatt aatttattat ccaagtcaaa aaaatgacga aagttataaa
     1741 acgcctaagg agacaaaaga acttgcatca tattcgttta ataaaaattc ttacttgaaa
     1801 aaactcgaat tgaatgaagg tttagaaaaa atcggtactt ttgcatttgc agatgcgatt
     1861 aaacttgaag aaattagctt accaaatagt ttagaaacta ttgaacgttt agccttttac
     1921 ggtaatttag aattaaaaga acttatatta ccagataatg ttaaaaattt tggtaaacac
     1981 gttatgaacg gtttaccaaa attaaaaagt ttaacaattg gtaataatat caactcattg
     2041 ccgtccttct tcctaagtgg cgtcttagat tcattaaagg aaattcatat taagaataaa
     2101 agtacagagt tttctgtgaa aaaagataca tttgcaattc ctgaaactgt taagttctat
     2161 gtaacatcag aacatataaa agatgttctt aaatcaaatt tatctactag taatgatatc
     2221 attgttgaaa aagtagataa tataaaacaa gaaactgatg tagctaaacc taaaaagaat
     2281 tctaatcagg gagtagttgg ttgggttaaa gacaaaggtt tatggtatta cttaaatgaa
     2341 tcaggttcaa aggctactgg ttgggttaaa gacaaaggct tatggtatta cttaaa
//
LOCUS       DAVAZT010000100         2332 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVAZT010000100 DAVAZT010000000
VERSION     DAVAZT010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2332
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.100"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            101..1078
                     /locus_tag="VQT45_002072"
     CDS             101..1078
                     /locus_tag="VQT45_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET2360321.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGVRFEAEK"
     gene            1075..2157
                     /locus_tag="VQT45_002073"
     CDS             1075..2157
                     /locus_tag="VQT45_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2360322.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFELLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(2221..>2332)
                     /locus_tag="VQT45_002074"
     CDS             complement(2221..>2332)
                     /locus_tag="VQT45_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET2360323.1"
                     /translation="LEDVMNQLQDVIQGLEKEVIKSIVNRRWTRMLFESR"
BASE COUNT          728 a          528 c          417 g          659 t
ORIGIN      
        1 aaagctaata gcttatttga aattttctcc tctctgttgg atagtcccgt ctatctatgt
       61 tataatgaaa gaaggattta aaatcggaaa aggagtattt atgctaaaat taggtgtcat
      121 cggaactggc gctatcagcc atcatttcat agaagcagcc cataccagtg gagaatacca
      181 actggtcgca atctattcta gaaaactaga aactgcagca acctttgctt ctcgctatca
      241 gaatatccaa ctattcgatc aattagaagt cttcttcaaa tcttcttttg atttagtcta
      301 tatcgccagt ccaaactcct tacattttgc tcaggcaaaa gctgccttgt ctgctggtaa
      361 acatgttatt cttgaaaagc cagctgtcac tcaaccacaa gaatggtttg atttgattca
      421 aacagctgaa aaaaataact gttttatctt tgaagcagct cgtaattatc acgagaaagc
      481 ctttactact atcaaaaact ttttagcaga taagcaagtg ttaggagcag atttcaacta
      541 tgccaaatac tcttccaaga tgcctgactt attggctgga caaacaccaa atgtcttttc
      601 agaccgtttt gctggtggag ccctcatgga tttggggatt tatcccctct atgctgctgt
      661 tcgtcttttt gaaaaagcta atgacgcgac ttaccatgct caacagcttg acaatagcat
      721 tgacctaaat ggagatggta tcctcttcta cccagactat caagttcaca tcaaggctgg
      781 aaaaaacatc acttccaatc ttccttgcga gatttataca acagatggaa ccttgactct
      841 caacacgatt gagcatattc gctcagctat ttttaccgac caccaaggaa atcaagtcca
      901 gcttcctatc caacaggctc ctcatacgat gactgaggaa gtcgctgcat ttgcacacat
      961 gatccagcaa ccagatctga atctctacca aacttggctg tatgatgcag gctctgttca
     1021 tgagctacta tataccatgc gccagactgc tggcgttaga tttgaggcag aaaaatgaaa
     1081 accaaactac cgactgaatg gcaagaactg agtgaccaac tcggtttcca agaattcacc
     1141 cccattcaaa ctcaactatt tgagctcctt cttgctggag aaaacctcct aggagtgagc
     1201 caaaccggaa ctggtaagac cctagcgtat ctcctaccaa gtcttctcag actacaaaag
     1261 aaaaaagccc aacaactctt gattctagca ccaaacacgg aacttgctgg acagattttt
     1321 gatgtatgta aaacgtgggc agaagctatc ggattgactg ctcaactctt cctttcaggt
     1381 tcaagtcaga aacgacaaat tgaacgtctt aaaaaggggc cagaaattct gattggaact
     1441 cctggccgta tctttgaact cattaaactt aaaaaaatca agatgatgaa tgtggaaacc
     1501 atcatcctgg atgaatttga ccaattacta gatgattctc agattcactt tgtagagaaa
     1561 atcactcact acgcacctcg tgaccaccaa ctggtctaca tgagtgccac gaccaagttt
     1621 gaccaagaaa agattgtgcc gaatacacgc actattgatc tctctgatca aaaattggac
     1681 aatatccagc atttctacat gcaggtagac caacgtcatc gagtggatat gctacgaaaa
     1741 ctggctcatg tagaggattt ccgtggtcta gtcttcttca atagcctgtc agaccttggg
     1801 aatgccgagg aaaaactaca gtatcgtgat atattggctg tttccctcgc tagtgatgtt
     1861 aatgttaaat ttagaaaaat catcttagaa aagtttaaag ataaccaact aaccctgctt
     1921 cttgcaactg accttttggc tcgtggaatt gatatcgata gcctagaatg tgtcgtaaac
     1981 tttgatattc ctagagatag cgaaacctac acacaccgtg ctggccgtac tggtcgtatg
     2041 ggcaaggaag gttatgttat cactctcgtc actcatccag aagaaatcaa aaaacttaaa
     2101 aagtttgcaa gtatccgaga aattgtccta aaaaaccaag aactctatat caaataaagc
     2161 cccattgctc tatacacatc cagtgtatgg agctttttta taagcaattc aattttatac
     2221 tcatctgctt tcaaaaagca ttctagtcca tctccgatta acgatggact ttatcacctc
     2281 cttctccaat ccttgtatga catcttgaag ttgattcatg acatcttcca aa
//
LOCUS       DAVAZT010000101         1834 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVAZT010000101 DAVAZT010000000
VERSION     DAVAZT010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1834
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.101"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(57..176)
                     /locus_tag="VQT45_002075"
     CDS             complement(57..176)
                     /locus_tag="VQT45_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HET2360324.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            complement(280..429)
                     /gene="blpO"
                     /locus_tag="VQT45_002076"
     CDS             complement(280..429)
                     /gene="blpO"
                     /locus_tag="VQT45_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HET2360325.1"
                     /translation="MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            complement(673..876)
                     /gene="blpN"
                     /locus_tag="VQT45_002077"
     CDS             complement(673..876)
                     /gene="blpN"
                     /locus_tag="VQT45_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HET2360326.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            complement(892..1146)
                     /gene="blpM"
                     /locus_tag="VQT45_002078"
     CDS             complement(892..1146)
                     /gene="blpM"
                     /locus_tag="VQT45_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HET2360327.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            complement(1296..1834)
                     /locus_tag="VQT45_002079"
                     /pseudo
     CDS             complement(1296..1834)
                     /locus_tag="VQT45_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT          578 a          411 c          251 g          594 t
ORIGIN      
        1 attaaagaaa ctcccctgta aattaagcta gcaaatacag gggagaaatt tattttttag
       61 agagtactat ccgtatcctt tttggaagat tttgaaaata tttttctaat taagtcatcc
      121 atataaggac caaatatacc aactactaaa ccaataataa aacttttaaa atccataatt
      181 accaccaaca tattgctgca taggctacac ctccaagtat agctccacct gcagcaccag
      241 ttacacctat tcctatagca aatggtccca atagaaatgt caaaccgttg ttgcacaccc
      301 atcaattgcg ccatatgcaa cccctgctgc acaactaatt tttcttcccc aatcaatatc
      361 tccaccttca acgcaagcaa gcatttcatt atccataact gcaaattgtg acatcatttt
      421 tgtatccata tagtatatca cttttcagtt acggaacaag tttaatataa aaattatcaa
      481 aaaaacatag gcaataaaga gaaaaattaa tttatcatag attagaaata atatgacaaa
      541 acaattcaat gatgttaatt caatagtctt ttgtttttta tcggagatac ttatggatag
      601 ataaataaga taggtttgaa aagcgaagag aataataaag aatatagcct tcataaaatt
      661 tagctttcat ttttatgatg tagcggtata ggctaaatat ccacaaacca ctgctcctcc
      721 aattcctcct attgcagcgc cccatggtcc tagaagtctc ccatatttca ctccacccgc
      781 tgcacaacct aaagcagcaa ctacagctgc tcctccggaa ttacctccat aaacctcact
      841 cagcattgtt tcatttatat tacaataagt attcatacaa gtctcctttt attaaaatcc
      901 acccgttgcc cctgttactc ctgcccaaag atccacacca aatttagctc ctatgtatcc
      961 acatgctccc ataaatggtg ctccaacacc actcgcagca caaatagctg tccctagccc
     1021 ccagccacca aaagcagcac caccaccttc caagacatta gtttgccaat tattcttgcc
     1081 tccttcaata ctagataaca tagttatatc catttcatga aattgttcca taatttttgt
     1141 atccatgaca aatactcttt tttattttta atttttgtct tgttgtaact ttgacaagtt
     1201 tagtatatca tcgtttttta aaatttttca tccagatctt gaatagtcat cgaaacgtct
     1261 tgaattgcaa aaattacatt agacttcctg caaaactaga atcctagttc atgattgata
     1321 ataccagcac tcaaattcat tcgtaatccg aagcgtttac gatgatttcg ataggttgtt
     1381 gaaaacattt taaacgtttt tactttggca aagatgttct caaccttgct tctctcctta
     1441 gatagcgcat ggttacaggc tttatcttca actgttagcg gtttgagttt gctggattta
     1501 cgtgaagttt gtgcttgagg atatatcttc atgagccctt gataaccact gtcagccaag
     1561 attttaccag cttgtccgat atttctgcga ctcattttga acaacttcat atcatgacaa
     1621 tagttcacag tgatatccaa agaaacaatt ctcccttgac ttgtgacaat cgcttgagtc
     1681 ttcatagcgt ggcatttctt tttaccagaa tcattcgcta attctttttt tagggcgatt
     1741 gatttgtact tccgtcgcat caatcattac cgtgtcctca gagctgagag gagttcttga
     1801 aatcgtaaca ccactttgaa caagagttac ttca
//
LOCUS       DAVAZT010000102         1671 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVAZT010000102 DAVAZT010000000
VERSION     DAVAZT010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1671)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1671)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1671
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.102"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            100..1575
                     /locus_tag="VQT45_002080"
     CDS             100..1575
                     /locus_tag="VQT45_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HET2360328.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNIVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
BASE COUNT          474 a          335 c          334 g          528 t
ORIGIN      
        1 tccagtattt gacaatattg aagcagctat taaagaacac ggattaagct aattctaatt
       61 tgttaacatt catataacat aaaaaaggga ggaactgtta tggatgcaat ctttgaccta
      121 atcggaaagg ttttcaatcc cattttagaa atgggtggac ctgtcatcat gttaatcatt
      181 ttgacagtat tggctttact ttttggagtg aaattctcca aagcgcttga aggtggtatc
      241 aaacttgcca tcgctcttac aggtatcggt gctatcatcg gtatgctaaa tggtgctttc
      301 tcagcatcac ttgcaaaatt cgttgaaaac actggtatcc aattgagtat taccgacgtt
      361 ggttgggcac cactcgcaac aatcacttgg ggttctgctt ggacactata cttcttgctc
      421 atcatgttga ttgtcaacat agtgatgcta gctatgaaga aaacagatac acttgacgtt
      481 gatatctttg atatctggca cttgtctatc acaggtctct tgattaaatg gtatgctgat
      541 aacaatggtg tgagtcaagg ggtttcactc tttattgcta cagcagctat cgtccttgtc
      601 ggtgtgttga aaattatcaa ctctgacttg atgaaaccta catttgatga ccttcttaac
      661 gccccaagtt catcaccaat gacatcaact cacatgaact acatgatgaa cccagttatc
      721 atggttttgg ataagatttt tgaaaaattc ttcccaggcc ttgataaata tgactttgat
      781 gctgctaaat tgaacaagaa aatcggtttc tggggatcta aattcttcat cggtttcatc
      841 cttggtatcg ttatcggtat tatgggaact ccacatccaa ttgcaggtgt tgcagatgca
      901 gataaatggc gtcttgttat caaaggatgg ttgtctcttg gtttgactgc cggtgtatct
      961 ttggaactct tctcacttat cggttcatgg ttcatcgcag ccgtagaacc actatcacaa
     1021 ggtattacaa acgttgctac taaacgtctt caaggacgta aattcaatat cggtcttgac
     1081 tggccattca tcgctggtcg tgctgaaatc tgggcttgtg ccaacgtact tgcaccaatc
     1141 atgttgattg aagcagtgct tctttcaaaa gttggaaatg gtatcttgcc acttgcaggt
     1201 atcatcgcta tgggtgttac tccagctctc ttggttgtaa ctcgtggtaa attgctccgt
     1261 atgattatct tcggaacact cttgttgcca ctcttccttc tttcaggtac acttattgca
     1321 ccatttgcaa cagaacttgc taaaggtgta ggtgccttcc cagaaggtgt gagccaaact
     1381 caattgatta ctcactctac tcttgaagga ccaatcgaaa aacttcttgg ttggacaatt
     1441 ggtaacacta caactggtga tatcaaagca atccttggtg cagtagtctt ccttgtattc
     1501 tatatcggta tctttgcttg gtacagaaaa caaatgatca aacgtaacga agagtacgca
     1561 gcaaaagcaa aataatgcgc tcctataaaa tataaactca atgaaaatca aagagcaaac
     1621 taggaaacta gccacaggtt gctcaaaaca cagttttgag gttgtagata a
//
LOCUS       DAVAZT010000103         1638 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVAZT010000103 DAVAZT010000000
VERSION     DAVAZT010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1638
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.103"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            108..407
                     /locus_tag="VQT45_002081"
     CDS             108..407
                     /locus_tag="VQT45_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic biosynthesis protein"
                     /protein_id="HET2360329.1"
                     /translation="MDSYAINFWESKGVGIDKKILEFIQKNITVIKNKNFLNKDFDIY
                     VKKIHNLFFVISTLVSKEQYMGIVSSQIHMFANRMGISPTIEVTMLDFFLREDSD"
     gene            409..1179
                     /locus_tag="VQT45_002082"
     CDS             409..1179
                     /locus_tag="VQT45_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SagB/ThcOx family dehydrogenase"
                     /protein_id="HET2360330.1"
                     /translation="MEKYFFDISIFEKIKKVLSYQSKYWEISKPRDKYSFKSQNRISG
                     SNSIKFKDFELDYELESLGKILLKRRSFLLNEFDKNASFDKLIYLLKTVFSPTNCKFV
                     FGEEVPLFSYPTSGALNSITPFVYIDNMDEVKNGIYEVKYDGLEFKKSMNIIDLETFT
                     PITSKNSDVQNNSFKKVNMIIMLCSNYENIFNKYGLLAYRLLHLEAGHIAQNIQLVST
                     ALGIKSLPMGGWFDDKIETFINEISDKKNIYLYAIAVG"
     gene            1199..1363
                     /locus_tag="VQT45_002083"
     CDS             1199..1363
                     /locus_tag="VQT45_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360331.1"
                     /translation="MNAEDKFRELENENKLLKLHNKELENEIQNGWKFWIWVTVPILG
                     LIYAIIQKIF"
BASE COUNT          601 a          180 c          267 g          590 t
ORIGIN      
        1 ataactatta ttacgaaaaa aaattcttgt gtaaaattct attgactttc tatattattt
       61 ttgtatttca taacgaatgt aatttaacaa gtgaagaaat tttaaagatg gattcctatg
      121 ctattaattt ctgggagagt aaaggggtcg gtattgacaa aaaaatcttg gaatttattc
      181 aaaaaaatat tacagttatt aaaaataaaa attttttgaa taaagatttt gatatttatg
      241 ttaaaaagat tcataattta ttctttgtca tttctacttt agtttcaaaa gagcaataca
      301 tggggatagt ttcttcccaa atacatatgt tcgcaaatag gatgggaatt tctcccacca
      361 ttgaagttac catgctagat ttttttctga gggaggattc tgattaatat ggaaaaatat
      421 ttttttgata tttctatttt tgaaaaaata aaaaaagtat tatcatacca atctaaatat
      481 tgggaaatat cgaagcctag ggataagtac agtttcaaaa gtcaaaatag aatatctggc
      541 tctaatagca ttaaatttaa agattttgag ttagattatg aactggagtc acttggtaaa
      601 atacttttaa aaaggagatc gtttttacta aatgaatttg ataagaatgc gagttttgac
      661 aaactgattt acttgttgaa aactgtattc tctcctacaa attgcaagtt tgtatttgga
      721 gaagaggttc ctttatttag ctatcctaca tcaggtgcgt taaattcaat tactcctttt
      781 gtttatattg ataatatgga tgaagtaaag aatggtatat atgaagtaaa gtatgacgga
      841 cttgaattta aaaaaagtat gaatattata gacttagaaa catttacccc aataacaagt
      901 aaaaacagtg acgtacaaaa taattcattt aaaaaggtaa atatgataat tatgttatgt
      961 tcgaattatg aaaatatttt caataaatat ggattattag cttatcgact tttgcattta
     1021 gaggctggtc atattgcaca aaatatccag cttgtttcta ctgcgctagg aataaaaagt
     1081 ttaccgatgg gaggttggtt tgatgataaa atagaaactt ttattaatga aattagtgat
     1141 aaaaaaaata tttatctcta tgcaattgca gttggataaa tttaaggagg aagtgtagat
     1201 gaacgcagag gataaatttc gcgaactaga aaatgaaaat aaacttctaa aacttcataa
     1261 caaggagctt gagaatgaaa ttcaaaatgg atggaaattt tggatatggg taactgtccc
     1321 tattttaggt ttgatatatg ctattattca aaaaattttt taattatgct agtttgtcag
     1381 gttgagtagt ttttgttcaa aatttaataa acttttttca atgaagatta tctaaagatt
     1441 gcttctcaga tgagaatggc ttctctatct tatataaatt atcttcatag agtgtcctgt
     1501 tattcatgtt atcacagaat agatagtttt tttggctcta taatatttgt agtgggtaaa
     1561 tcccctatag atattatgga gcctattttt gtgtagaaaa aaagtcccat atcatctata
     1621 atgaaaagca accaaact
//
LOCUS       DAVAZT010000104         1586 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVAZT010000104 DAVAZT010000000
VERSION     DAVAZT010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1586
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.104"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            84..491
                     /locus_tag="VQT45_002084"
     CDS             84..491
                     /locus_tag="VQT45_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2360332.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLYEATSFKEVQKPLENFN
                     HIAWFPIDEAIQNLKRGSHKWAIESWKKQHKIG"
     gene            656..955
                     /locus_tag="VQT45_002085"
     CDS             656..955
                     /locus_tag="VQT45_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HET2360333.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVNEANIKTLYSEKLIGISIPIK"
     gene            1216..1539
                     /gene="tnpB"
                     /locus_tag="VQT45_002086"
     CDS             1216..1539
                     /gene="tnpB"
                     /locus_tag="VQT45_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HET2360334.1"
                     /translation="MMIVLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTSEQVDWLMKGFS
                     ITPQI"
BASE COUNT          544 a          314 c          282 g          446 t
ORIGIN      
        1 actataataa taacgatact agataatgag gaaaatgcaa tggcaaaccc aactttcgga
       61 gaaaaaaagc gaatacagac tatattgctc gctatggcgt atatgcagtt atccctaatc
      121 ctgaacaaaa acaaattgtt cttgttcaag aaccaaatgg tgcttggttc ctaccatgtg
      181 gagaaattga agcaggtgaa aatcatcagg aagccctaaa gcgtgagttg attgaagagc
      241 ttggtttcac agcagaaatt ggtacctatt acggacaagc tgacgaatat ttctattctc
      301 gtcatcgtga tacctactac tacaatcctg cctacctcta tgaagcaact tctttcaaag
      361 aagtacaaaa gccactagaa aactttaatc atattgcctg gttccctatt gacgaggcta
      421 tccaaaacct taaacgtggt agccataaat gggccattga atcttggaaa aaacagcata
      481 agattggcta atactcttcg aaaataaaat tcaaaccacg tcagcgtcgc cttaccgtac
      541 tcaagtatag cctgcggcta gcttcctagt ttgctctttg attttcattg agtataaatc
      601 aagcgacttt attcaaaaag tgctataata gaattagaaa atcggaggaa atattatgaa
      661 gcttatcaat acgacaaact cacactcgca acttgtaaaa agtcaactag aaagtaccga
      721 tgcaaccctt gttgaggttt attctgcagg gaatacagat gttattttta cccaagctcc
      781 gcttcactat gaaatcctca tctcaaacaa acaccgtgct attcgtgagc ctgaaatcga
      841 aaccattcaa gaatttttct tgaaacgtaa aattgataag acctctgtta atgaagccaa
      901 tatcaagaca ctctactcag agaaattaat tggaatttca atcccaatca agtaagaaaa
      961 ttgagtaaaa actcgatttg agagaaagtc caataagtct ttccataaca aaacgcatag
     1021 taacaagagt ttctacaccc actattatac gtttttatca ttttgaaatc tgctgctaat
     1081 caatgaagaa gcaaagatca aactaggcag ctagttacaa gttacgtaag cgcgtcataa
     1141 caaggtatct atcctaattc cccaacttcc agtatactag ataaaaaata attatcagag
     1201 gaaaggtatt gtactatgat gattgtacta agtgatttag gtcaagttca ccttgtttgt
     1261 ggcaagacag atatgaggca gggaatagac tcattagcct atgtagttaa aacccacttt
     1321 gaattggatc ctttctccgg tcaagtcttt ctcttttgtg gtggacgtaa agaccgcttt
     1381 aaagcccttt actgggatgg tcaaggattt tggctactat ataaacgctt tgagaacggc
     1441 agactgactt ggcccagtac agaaaaggat gtcaaagctc tcacatctga acaagtagac
     1501 tggcttatga agggcttttc tatcactccc caaatatagt ggatttaaac tagaatagta
     1561 cacctctact tctaaaacat tgttag
//
LOCUS       DAVAZT010000105         1455 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVAZT010000105 DAVAZT010000000
VERSION     DAVAZT010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1455
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.105"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(412..804)
                     /gene="rpsI"
                     /locus_tag="VQT45_002087"
     CDS             complement(412..804)
                     /gene="rpsI"
                     /locus_tag="VQT45_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HET2360335.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(824..1270)
                     /gene="rplM"
                     /locus_tag="VQT45_002088"
     CDS             complement(824..1270)
                     /gene="rplM"
                     /locus_tag="VQT45_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HET2360336.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
BASE COUNT          420 a          290 c          279 g          466 t
ORIGIN      
        1 cccaaactct tcacacaaga gttctaactt acccattcta tggaatcttg cattatccat
       61 aatatagtag attgaaacta gaatagtaca cctctacttc taaaacattg ttagaattcg
      121 atttgactat cctcggtttg tcctattctt atttcacctt actataaaaa taaggtaaac
      181 ttttcaaaaa aacacgaaaa aagcacccat agggcaaacc tttgagtgct ttgaaacatt
      241 gatataattg tattgattag cgttttgagg caactgacct tgtcaggttg cagccacatt
      301 tgtaagcaac taaagtcgca acaactgtgt caattgcacc aatttagtaa gaaagtataa
      361 aaaaagaaca ccccgaaagg tgctctgtat aagtatagta attctttcga attaacgttt
      421 actaaattgt gatgctttac gagctttctt aagacctggt ttcttacgtt caactttacg
      481 tgagtcacgt gtaagaagtc ctgcgcgttt caatgaatcg cggaagtctg ggtctacttg
      541 aagaagggca cgagcgatac cgtgacggat agctcctgat tgaccagcgt atccaccacc
      601 tacaacgtta acgaaaacgt cgtatgaacc tacagttgaa gtaactgcga atggttggtt
      661 gatgacaaga cgaaggtcag catgtgggat gtactcttca acatcttttt tgttaacagt
      721 gattttacca gttcctggaa caaggcgaac gcgtgcaaca gcgtttttac gacgtccagt
      781 acctgcatat tgtgcttgtg acatacttta tttgttcctt tccttagata agtcctgaaa
      841 tgtcaagaac ttctggttgt tgtgcagcat gagtgtgctc agctccaaca aatactttca
      901 acttcatacc ttgagcgcgt ccaagtgtat tgtgtggaag cataccttta actgatttct
      961 caatcaaacg tactgcattt ttagaacgaa gttcacctgc agagatttgt ttcaatccac
     1021 ctgggtggtt tgagtgagtg tagtagattt tatcagttgc ttttttacca gtcaatttaa
     1081 ctttttcagc attgataaca atcacgaagt cacctgtatc agtgtgtggt gtaaatgttg
     1141 gtttgttttt tccgcgaagt acgctagcaa ctactgcaga aagacgtcca agtggtacat
     1201 cagttgcgtc aactacgtac catttacgtt caacttggcc tggtttagcc ataaatgttg
     1261 ttttgttcat gatttctcct atatatagtt cgatttttgt ttacggtgat gggtgttcct
     1321 tcccatcgaa aagtatttgg aaggttccgg ggcctttcaa atggggtaaa caataccgcc
     1381 tactatcata ccaaatttca cccctaaaag tcaatagata tgaaaaatat ttttcggtaa
     1441 cttctcaaag taact
//
LOCUS       DAVAZT010000106         1389 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVAZT010000106 DAVAZT010000000
VERSION     DAVAZT010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1389
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.106"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(704..1389)
                     /locus_tag="VQT45_002089"
                     /pseudo
     CDS             complement(704..1389)
                     /locus_tag="VQT45_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          386 a          283 c          287 g          433 t
ORIGIN      
        1 tacgtgacag agtccagttc tatcagaccg ttcgttttac agacacaagt gaagtaggat
       61 tacttcgatt agttgtttac cccttcgctc cacttccatt acagaagttt cctcactact
      121 atgggctcgg ctgacttctc atgattcgtt gttactacgc tttcggcgct catgagacct
      181 cacgggataa gccgtacatc tttcctcgtt tatacaagat atgaggacgt taaaaggtta
      241 caatgaaaat aggaaatctg acgcagagtc tttagactct aggaagattt atctttttca
      301 catagacctt agtccgaatt caattactct cgtgatttac gcatataggt tacgactacc
      361 tttttggact ttagagtttt aagccccctt atccgctgta tacgccttac tatcacgttc
      421 ctgttcgtag agcctcgatt tcgctatccc ttcctctgac gattcttatt tcctgcgtca
      481 gacttaaaac ggtctatccc cagaccgttt taatccgcta cctcacgata gtcaggcttg
      541 ggaatcgcta ttgggttcac cggtagcagg tgcccacgga ggacttacac ctcagatgca
      601 cgacatgccc gtcgtactta aaatcagcct aaatgattca ggctgatttt tctattgatt
      661 caaaaaaacg gctctttgtc aactgtagtg ggttgaagaa aagctaagat cgagaaagga
      721 caaatttcgt cctttctttt ttgatattca gagcgataaa aatccgtttt ttgaagtttt
      781 caaagttccg aaaaccaaag gcattgtgct tgataagttt gatgagatta ttggtcgctt
      841 ccaatttggc gtttgaatag ggtagttgaa gggcgttgat aatcttttct ttatctttga
      901 ggaaggtttt aaagacagtc tgaaaaatag gatgaacctg cttcagattg tcctcaataa
      961 gtccgaaaaa tttctctggt tccttattct ggaagtgaaa aagcaagagc tgatagagct
     1021 gatagtggtg tttcaagtct tccgaatagc tcaaaagctt gtctaaaatc tctttattgg
     1081 ttaaatgcat acgaaaagta ggacgataaa aacgcttatc actcagttta cggctatcct
     1141 gttgtatgag cttccagtag cgcttgatag ccttgtattc atgggatttt cgatgaaact
     1201 gattcatgat ttaaacacgc acacgactca tagcacggct aagatgttgc acaatgtgaa
     1261 agcgatcaag aacgatttta gcattcggga gtgaaacagt ctgggagact gtttcagcct
     1321 gagcctagaa atttgaaagc gaagctgtct agctaagtca tagtaagggc taaacatatc
     1381 catagtaat
//
LOCUS       DAVAZT010000107         1326 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVAZT010000107 DAVAZT010000000
VERSION     DAVAZT010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1326
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.107"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            236..676
                     /locus_tag="VQT45_002090"
     CDS             236..676
                     /locus_tag="VQT45_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2360337.1"
                     /translation="MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            673..1131
                     /locus_tag="VQT45_002091"
     CDS             673..1131
                     /locus_tag="VQT45_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HET2360338.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
BASE COUNT          421 a          288 c          249 g          368 t
ORIGIN      
        1 ccttgccaga gggagtaaaa tagtggtata ctcaataaaa atcaaagagc aaactagaaa
       61 gctaggcgca gacagctcaa aacactgttt tgaggttgta gataaaactg acaaagtcaa
      121 caactatcct acggcaagac gacgctgacg tggtttgaag agatttttga agagtattaa
      181 taaaggtgta caagaagtga gattaatttt gtatgaaaaa caaggagaga aatttatgaa
      241 agtagaatta cagattagtg agacttacga ggaggaaaag ctgattgtcc aagcacctca
      301 gccgacagat aaagttcaga aagtcatcga gttcgcagaa aatctggacc aaagagaaaa
      361 aatcaaaggg aaaatcgatg atcaggtcta tctagttgag attggcaaga ttcagcgctt
      421 ctatatcgag aatcggaagg ttctagcaga aaccgcgagt cagacctaca gcattgattt
      481 gcgactctat caggttctta aactcttgcc aaccaatttt atccaaattt cccaatcaga
      541 aatcatcaat atcgattcca tctctcacct caagctcacg ccaaacggtc tggtagaaat
      601 tttcttgaaa aacgaaagct tcacctactc ttcacgccgt tatctaaaaa ccatcaagga
      661 gaaattagaa ctatgaaaaa acaagtattt cacgatgcag ctgccggtgt tcttatcggc
      721 ctcatcctct ctatcctctt ttcactcatt tatgcaccaa atacctacgc accactaaat
      781 ccctactctc tcatcggcca agtgatggat cagcatcagg ttcacggtgc cttggtcttg
      841 ctctactgca cacttatctg ggcagccatt ggtatgctct tcaactttgg caatcgctta
      901 ttcagccgtg actggagcat gcttcgtgcc actctgactc atttcttcct tatgctggct
      961 ggctttgtcc cactagcaac tcttgctggt tggttccctt tccactggat tttctacctc
     1021 cagctcatta tcgagtttgc gattgtctat ctcatcatct gggctattct ctataaaaga
     1081 gaggctaaaa aagtagatca catcaatcaa ctcttggagc atagaaaata ggaacctcat
     1141 aataagcaaa tccgagaaag aaacttctcg gtttttcttt atcctgctgc accttactat
     1201 agtgaaatga aataagaaca ggataaatcg atcaggacag tcaaatcgat ttctaacaat
     1261 gttttagaag cagaggtgta ctattctagt ttcaatcctc tatatcataa cagttatttc
     1321 agatct
//
LOCUS       DAVAZT010000108         1190 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVAZT010000108 DAVAZT010000000
VERSION     DAVAZT010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1190
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.108"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            239..>1190
                     /locus_tag="VQT45_002092"
     CDS             239..>1190
                     /locus_tag="VQT45_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET2360339.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HNEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRR
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
BASE COUNT          413 a          210 c          249 g          318 t
ORIGIN      
        1 agccacctta ccttagtcaa gaattagatg tttcactatg tttgagtaag ttgatgattt
       61 catttgataa caggtttgaa actgttaggc taggtggcca aggctaatca tagccttggt
      121 ttagctgaaa aaacaggttc aagggttcct gttgtcaaat gaaatgtgat ttaaggtata
      181 agaaaacacc tctgtgctat acttgttgtt caccacaaac acaaggaaag gcacagagat
      241 gcaagaacat tataccccaa aagggaaaca tttgacaata gataaccgtc gcttgattga
      301 gcggtggaag aatgaaaata agtccaatcg tgaaattgca ggcttgttag gaaaggcgcc
      361 tcaaacgatt cataatgaag tcaaaagagg tacaacttta caacaagtga gaaaagggct
      421 atacaaaaag gtctattctg ccgattacgc acaaactgtt taccaattca atcgaaaacg
      481 gtcggtgaaa aagttaattt taacaaagga aatcagagag aagatcttac actatcataa
      541 gcaaaaattt tcgcctgaaa tgatggttaa caagaagcaa gtgaaagttg gtatttcaac
      601 catctactac tggtttcata atggtcattt aggattgacg aaggccgaca tgctttatcc
      661 cagaaaaagg aaaggtgtca agaagcaagc tagtccgaac tttaagccgg caggtaaatc
      721 tatcgaagaa cgtcctgacg ttattaatct tcgcttggaa aatggtcatt atgaaattga
      781 taccgtccta ctgactaaga taaaaaatta ttgcctgtta gtcttaaccg accggcggag
      841 cagacaccaa attataaggt taattccaaa taaaactgct gaatctgtca atcaggcgct
      901 tacgttacta ttaggggagc atcgtattct gtccattact gcagataatg gttcggagtt
      961 caaacgattg tctgaggtat ttcctgagga acatatctac tacgcacatg cttactcttc
     1021 atgggagaga ggttcaaatg aaaatcataa tcgattaatt cggagatggt tacctaaagg
     1081 aaccaagaaa acgactccga aagaagtagc ttttatcgaa aattggatta acaactaccc
     1141 taaaaaatgc ttggactaca agtcgccaag tgaatttctt ttgggtggct
//
LOCUS       DAVAZT010000109         1142 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVAZT010000109 DAVAZT010000000
VERSION     DAVAZT010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1142
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.109"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..1122
                     /gene="rlmD"
                     /locus_tag="VQT45_002093"
     CDS             <1..1122
                     /gene="rlmD"
                     /locus_tag="VQT45_002093"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET2360340.1"
                     /translation="CGGCQIMHLHYDKQLEFKTDLLHQALKKFAPAGYENYEIRPTIG
                     MQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELKDCLVQDKETQVIANRLAELL
                     TYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNRQLNLTQLVKELVKDFPEVVT
                     VAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSLSPRAFYQLNPEQTEVLYSEA
                     VKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDIIPEAIEDAKRNAKRMGFDNT
                     HYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLLDTILTYVPEKMVYISCNVST
                     LARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKKV"
BASE COUNT          387 a          196 c          243 g          316 t
ORIGIN      
        1 tgcggaggct gccaaatcat gcacctgcat tatgataagc agctggagtt caagacggac
       61 ttacttcatc aagcgctgaa aaaatttgct cctgcaggat atgaaaatta tgaaattcgt
      121 ccaactattg gaatgcagga accaaaatat tacagagcta agttacaatt tcagactcga
      181 aaatttaaaa atcaggtcaa ggcgggctta tatgcacaaa actctcacta tttagtagag
      241 ttgaaagact gcctggtaca agataaggaa acccaagtga ttgctaatcg cttagcagaa
      301 ttacttactt atcaccagat tccaatcacg gatgagagaa aagttctagg tgtccgtact
      361 attatggtcc gacgcgcgag aaagaccgga caggttcaga ttattattgt tacaaaccgc
      421 cagcttaatt taactcaatt ggtaaaagag ttggttaaag atttcccaga agttgtgaca
      481 gtagctgtta atacaaatac agctaaaacc agtgagatat atggtgaaaa gacagagatt
      541 atctgggggc aagagagtat tcaagaaggt gtactcaatt atgaattttc actatcccct
      601 cgagcttttt atcaactaaa tcctgagcaa acagaagtcc tctatagcga agcagtaaaa
      661 gcgctggatg ttgataaaga agaccatttg attgacgctt attgtggagt tggaacgatt
      721 ggatttgcct ttgcaaagaa agtaaaaaca ctcagaggta tggatattat tccagaagct
      781 attgaagatg ccaagcgaaa tgctaaaaga atgggatttg acaatactca ttatgaagct
      841 ggaacggcag aagagattat tcctcgttgg tacaaggaag gctaccgagc agatgctttg
      901 attgttgacc caccacgtac aggtctggat gataagttat tagatactat tcttacttat
      961 gtaccagaaa aaatggttta tatttcttgt aatgtttcga ccttggctcg tgatttggta
     1021 cgcttagtag aagtctatga tcttcattat atccagtcgg tcgatatgtt cccacataca
     1081 gctcgaactg aagctgttgt aaaattaata aaaaaagttt aaaaaaggtg ttgacaaaac
     1141 at
//
LOCUS       DAVAZT010000110         1094 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVAZT010000110 DAVAZT010000000
VERSION     DAVAZT010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1094
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.110"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            122..590
                     /locus_tag="VQT45_002094"
                     /pseudo
     CDS             122..590
                     /locus_tag="VQT45_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            883..1053
                     /locus_tag="VQT45_002095"
                     /pseudo
     CDS             883..1053
                     /locus_tag="VQT45_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT          394 a          162 c          222 g          316 t
ORIGIN      
        1 gagaagagga ttgccatctt ctccattttt atgtgcagag ttatagtggc ttgatgctgg
       61 gaaagtacac tgtgactgct aaaacattcc tagaagctgc tttgatttcc ctaatctatt
      121 tatgcaaatt ttatgttatt ttactataac agttgttgct aagccaaata atagtgggga
      181 agttcattta gacgtaagca ttgaagataa tcagggaggt agtgggtata atttcagttc
      241 tgtttcaagt agctcacaaa cagctaaata tgaaggaact ggttataata acaattcatc
      301 attatatata acgattgata aaacgtctga tgcaacagct cttttgaaat taaagttgaa
      361 taatgttgat aatcaacctg ctactgaagt tcctagttca ggaattactg taaaattaaa
      421 tgctaaagat aatgctggaa actggacaag tgcttcgaat aaagacaagt gcttcgaata
      481 aaaaagaaat aacagtaaaa attgtttctg ctaaaccgac atatccagac aaaatcttag
      541 tgaaaaatcc tgataatata aaagatacag aaaaaaatgc cattattgaa aaattgaaag
      601 aggcaaataa aaatcatcca gcaggagctc caacctttgc taaaggtgaa ggagagcatg
      661 caaatgatat tgtagcaact tattcagatg gtacaactta ttatgtaccg ttaaatgatg
      721 tgacaaaata tgcgaggtag tggctgtacc actcacttat tcacctcccc gtgatttgta
      781 gtagtgatag gctttctcac tattattata aaacaaaata aagatcacaa cactttttca
      841 ttctgtgttg tgccttgagt gaaacgaaag gaatgaatta taaatatgaa aagtatagtc
      901 actagcatag atgagcgctt gcgtactcgc ctacgagtga ttatctggaa gcaatggaag
      961 aagaaatcga gacgattatg gggattgctt aagttagggg ttcctaaatg gatagcagat
     1021 aaggtatctg gctggggcga ccactatcaa ttatagtaaa atgaaataag agtaggacga
     1081 attgatcagg gcag
//
LOCUS       DAVAZT010000111         1092 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVAZT010000111 DAVAZT010000000
VERSION     DAVAZT010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1092)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1092)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1092
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.111"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(1..311)
                     /locus_tag="VQT45_002096"
                     /pseudo
     CDS             complement(1..311)
                     /locus_tag="VQT45_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(547..858)
                     /locus_tag="VQT45_002097"
     CDS             complement(547..858)
                     /locus_tag="VQT45_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360341.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYVCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(873..>1092)
                     /locus_tag="VQT45_002098"
     CDS             complement(873..>1092)
                     /locus_tag="VQT45_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HET2360342.1"
                     /translation="VEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELLTIKVPQPV
                     QAGDMVRALKEGLINLYKEDGTSVTVRA"
BASE COUNT          340 a          216 c          183 g          353 t
ORIGIN      
        1 aagtcttgtt tgatagcttc aaacttttca ggactttcaa gataggcatc cacaaccgcc
       61 ttgtagcagt tggttactgt taatacatag tgaatagact ccatacgtcc ttcgattttt
      121 agactgtcca caccattttc aatcatatct ggaatgtggt caatcataga catgtcaacg
      181 gctgacattg aaaattcttc tggaatctca ccctgcaaac tcttacgttc tttcccaaat
      241 ggcatatcgt aaaggtcgta tttccaacgg catgactgag aacatccacc acggttggca
      301 tcacgcatac tctagacgca attctaatct tttagacttt gcataataac tgttaaacag
      361 ttgaaaatta acccagtttt aacaagtagt caaaatacca gataaaggaa aaaaagtctt
      421 taaaatctta aaaacgcata gtatcaggta ttgaacaatc ttgatattat gcgttttatt
      481 gtgggaagat ttacttcatt ttctcttgga attgagtttt ctcctacttc aaaactagat
      541 gatttgctat ttaaaatagc gttccttatg attttggcaa cctggattaa agcgagaaaa
      601 acaaaagggg caacttaagc tttctttata ttgcttatat gttagtagtt ttagacaaac
      661 accacataaa ataggcttat cctgtatcaa agataaggga tacggctcaa aagggtgatt
      721 ttctaatgaa tcatgacacc gataacaagc atagtacttt ttacaaacat agcattgtaa
      781 agcaataata tccagcttgc tatggtaatg aatgcatctt gtttgcttat ccactaagaa
      841 accctgtgcc tctatcattt ccttttcctt tcttaagctc gaactgtgac gctggttcca
      901 tcttccttat aaagattgat gagtccttct tttaatgcac gaaccatgtc tccagcttga
      961 acaggttgag gcaccttaat agtcaatagt tccattggat ttggagcgcg gtcgatttta
     1021 ttgcctttgg catcatgcaa atcttcaata taggtttcaa aatgacggaa acctggacca
     1081 taaaactcaa ct
//
LOCUS       DAVAZT010000112         1070 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVAZT010000112 DAVAZT010000000
VERSION     DAVAZT010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1070
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.112"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(1..78)
                     /locus_tag="VQT45_002099"
                     /pseudo
     CDS             complement(1..78)
                     /locus_tag="VQT45_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(527..925)
                     /locus_tag="VQT45_002100"
     CDS             complement(527..925)
                     /locus_tag="VQT45_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2360343.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT          328 a          201 c          160 g          381 t
ORIGIN      
        1 acgcttgatt tcagtgtgga tagtttgagg agcttttcca agtagagagg caatttctct
       61 atttgatttc cctttgttcg ccttttgtag tataatggtt ttgcatctct gtgcctttct
      121 tgtgtttgtg gttgaacaac aagtataaca caaaggtgtt ttcttatgcc tacaagagct
      181 ttcattattt ccattttctt ttggatttca ctctattctg aaaaacttgt gtatatttac
      241 tgaagctagc aagtcttacc tgtaaattta atgaaagcaa cacaaaatcc gagaggggaa
      301 tctcggatta atgtcaattt aaaaagatag agagttttta gtttaaataa attgttttaa
      361 aatatcaaca acatcacttc ttttcttaac ctgataagcc ttgattccta attttggggc
      421 tacgattata ttgtcctcaa tatcgtctag aaagacacaa tttctaggtt ataactggta
      481 tttatcgata gttactcata tatatcagtc cacctccata ctcaccttac agattctttt
      541 gataataata tctttgccta atgtagagat agtcttgcaa agaaaaaact tccttgtagc
      601 catgtttctg ataaaagtcc ggtgcctgga actggtaagt attgacaaag gcaaaacaac
      661 aatttcgatt cttagcttca ctttctgcct gttgcaatag ttttgaaccg attccttgcc
      721 ctcgcagttc ctcttttaca aacaaatact cgatttctag ccaatttcca aaagtctctg
      781 ctatcaaacc cgcaaggaga ttgccctttt catcttcgac ataaagatta agtggctcac
      841 tttcagcctc ttctcttttt gaacggttat aaacacgaat cagattccct atttcttgcg
      901 atttatgtga ttccttattt tccaatctaa agtataatga aatgaaataa aacatgcgca
      961 aatcgattaa ggaatttaat ctaatttcta acaatgtctt agaaatcaaa gtgtactatt
     1021 ttaacttcaa tgcactatac atctaatact caataaaaat caaagagcaa
//
LOCUS       DAVAZT010000113         1054 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVAZT010000113 DAVAZT010000000
VERSION     DAVAZT010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1054
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.113"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..555
                     /locus_tag="VQT45_002101"
     CDS             <1..555
                     /locus_tag="VQT45_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2360344.1"
                     /translation="KDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGTE
                     IPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIPA
                     THNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPIS
                     NHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(503..1048)
                     /locus_tag="VQT45_002102"
     CDS             complement(503..1048)
                     /locus_tag="VQT45_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2360345.1"
                     /translation="MNWVVIKIKDIFSINTGLSYKKGDLSINNKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQLWK"
BASE COUNT          380 a          165 c          153 g          356 t
ORIGIN      
        1 aaagacgaaa caacctctta tcctatatat gaaatcccag aagcatggag atatattaaa
       61 tttgctagcc tagttaactt cagaatagga aaaactcctc cacgcagtga agctactttt
      121 tggggaactg aaataccttg ggtatctata tcagatatgc ctatatctgg ttatgtaact
      181 aatacgagag aatctatttc taaattagca ttaaaatcaa agaaaataga catttcacct
      241 aaaggaactt tattaatgag ttttaaatta tctattggaa aagttgccat attggatatt
      301 cctgccactc ataatgaagc cattatatcg atattcccct atgctaataa agaaaatatt
      361 atcagagatt acttaatgat atttttgcca cttatctcta ctttaggtga ttcaaaagat
      421 gctataaaag ggaaaacatt aaatagtacc agtatctccg aattattaat ccctatttct
      481 aatcatgaag agatgaaaag aatcatttcc aaagttgatt tactttttca aaaagtttct
      541 caactttttg agtaataagt tcctgttcct caaaaggagc taacggaatt aatagctcgc
      601 ttagtgtagt tttaggaata ttatataaag cttgacctga tagtttagtt attgctttca
      661 attgtttata aaataacgga gaggacaagt taaataatag aaattttgaa ataatctctg
      721 aactttcgaa tggtgttaat tggaaaataa atccaccagc cacaacacca tcatagtctt
      781 tatcgattct tgcaaacttt ccaatatgtt ctaaagaggt tgatacaggt gttattagct
      841 gattatgttt taaataaact tgctcagagg agatgaattg tgtatcaatg tagtaatcat
      901 tatccaacag agaaaattct aaaggcttaa tattaccacc acgtataatt ctaacacctt
      961 tattattaat gcttaaatcg cccttcttgt aagaaagacc tgtatttatt gaaaaaatat
     1021 cttttatttt tataacaacc caattcatag gtat
//
LOCUS       DAVAZT010000114         1035 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVAZT010000114 DAVAZT010000000
VERSION     DAVAZT010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1035
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.114"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..990)
                     /gene="ltrA"
                     /locus_tag="VQT45_002103"
     CDS             complement(<1..990)
                     /gene="ltrA"
                     /locus_tag="VQT45_002103"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HET2360346.1"
                     /translation="MSKLLDKILSRDNMLEAYNQVKSNKGSAGIDGITIEEMDGYLRQ
                     NWRLTKELIKQRKYKPQPVLRVEIPKPNGGIRQLGIPTVMDRMIQQAIVQVISPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAAAKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVWRFKLKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSL"
BASE COUNT          270 a          226 c          183 g          356 t
ORIGIN      
        1 caatgagaaa tagtttatcc atcctcgaat agacaaattc agttgctcaa tacgtcttgt
       61 taggtctata ctccatttcc tctgtgttag tttcttcaat ttaagcttaa atctccaaac
      121 actatcttga tgtggacgac ttttccaacc atctgatgat ttccagaacc cgaaacctag
      181 atatttcaac tctcttggtc tggtaatctt agtcttggtc atgtttactt tcagacctag
      241 ccgtttctca ataaaacgac tgactgaata catcacacgc ttagcggctg cctcgcttcc
      301 gaccgtaatc acacaatcgt ctgcgtagcg aacaaatcga agccctctct tttctaattc
      361 cttgtccaat tcattaagca tgatattgga taagagagga gataaatttc ctccctgtgg
      421 cgtgccaact agcgttttat aacgttgacc gttaatgata acacctgaat gaagatattt
      481 acgaatcaag gattccgtat ctccgtcttc gataatgtta tgtactaagg acatcaatct
      541 atcttgagga actgtatcga aaaatttctc taggtctatg tccactatcc actcatagcc
      601 gtcatttaag tactctaaga gcttcatgat ggctttttca catgacctat ttggtctgaa
      661 tccatagctc gtatctgaga aatggggttc acaaataggg ctaataactt gaacaatggc
      721 ctgttgaatc attctatcca taactgttgg aattcctagt tggcggatgc ctccgtttgg
      781 tttgggaatc tcaactctaa gaactggttg aggcttatat tttctctgtt ttatcagttc
      841 cttagtcagg cgccagtttt gtctgagata gccatccatc tcttcgatag taattccatc
      901 aatcccagct gagcctttat tagattttac ttgattgtag gcttcaagca tattgtcgcg
      961 tgataatatt ttatctagca attttgacat gtgcctattc ctttcttgtt ttggtgcctg
     1021 agggacatct tatat
//
LOCUS       DAVAZT010000115          943 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVAZT010000115 DAVAZT010000000
VERSION     DAVAZT010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..943
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.115"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..223
                     /locus_tag="VQT45_002104"
     CDS             <1..223
                     /locus_tag="VQT45_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2360347.1"
                     /translation="QAQTPRKSSKLKPLTAEDKACNHVLSKERSKVENIFAKVKTLKM
                     FSTTYRNHRKRFGLRMNLIVGIINHELGF"
     gene            240..818
                     /locus_tag="VQT45_002105"
                     /pseudo
     CDS             240..818
                     /locus_tag="VQT45_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
BASE COUNT          357 a          123 c          181 g          282 t
ORIGIN      
        1 tcaagcacaa actccacgta aatccagcaa actcaagccg ctaacagctg aagataaagc
       61 ctgtaaccat gtgctatcta aggagagaag caaggttgag aacatctttg ccaaagtaaa
      121 aacgcttaaa atgttttcaa caacctatcg aaatcatcgt aaacgcttcg gattacggat
      181 gaatttgatt gttggtatta tcaatcatga actaggattc tagttttgca ggaagtctat
      241 tatcaaaaat accatcagga ttatataaga ttgatacagg aaaagtttta ttttatggta
      301 taaatattaa tcaaatagat aaaaaaatat taagtcaaaa tttaggagta gttccacagg
      361 attcattttt attgaaccga agtattcttg ataatataac tttaaagcac gaagttactt
      421 cacaaaagat agaggaagtt tgtaaagcag ttcaaatcta tgatgaaatc atggctatgc
      481 cgatgaaatt taatactatc atctcagaga tggggtcaaa tatttcaggt gggcaaaggc
      541 aacagatagc actggcacgt gcattaataa ataatcctag tattgtaatt ttagatgaag
      601 caactagtgc attagacact attaatgagg aaagaataac aaagtatata caaagtcagg
      661 gttgtactca aataattata gctcatagat tgtcaacgat taaggatgcg gatattattt
      721 ttgtaatgaa aggtggtaag attgttgagt caggaaatca taagtactta ataactcttg
      781 gtggagagta ctacagctta tatacaaaaa ggaaatgagg tgtaaagaaa atgaagaaag
      841 aaaatgaata tgtaatttta acaatagcct cactaggggt gatgattgga atagtgtttg
      901 caattttttt agattttcca gttgaatatg gtatttcttt agg
//
LOCUS       DAVAZT010000116          830 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVAZT010000116 DAVAZT010000000
VERSION     DAVAZT010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..830
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.116"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            21..830
                     /locus_tag="VQT45_002106"
                     /pseudo
     CDS             21..830
                     /locus_tag="VQT45_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558050.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element IS1515 family transposase"
BASE COUNT          266 a          174 c          162 g          228 t
ORIGIN      
        1 aaaagtgtta tactattttt atggaaacag tatacgacaa agcacaaaaa cttaactcaa
       61 aaaacttcaa actattgatt ggtgtcaaaa aggaaacctt tcaactcatg ctagaacacc
      121 tgaattcagc ctatcagatt cagcaccgaa aaggtggacg tccacgtagt ctgcccatgg
      181 aagaccagct cattatgacc ctccgttact tgcgatatta tcccactcag cgtctgctgg
      241 cctttgattt tggcgtcggt gtagctacgg taaatgccat catcacttgg gtggaggata
      301 cacttcgtgc gtcaggtagc tttgatttgg accatttaga agccccgagt gctgctgtgg
      361 ctattgacgt gaccgaaagt ccgattcagc gtccaaaaaa aaccaaagca aaaattattc
      421 tggtaaaaag aaacgacaca ccttaaaaac tcaaattatg ctggatttga cgacacataa
      481 agtctgtcaa atggcctttt ctgacggaca tacgcatgat tttactctct tcaaagaaag
      541 tattggacaa agtttgcctg aaacgacgct tgcctttgtt gacctaggtt atttaggcat
      601 cttgaaattt catgagaata ctttcattcc tgctaaaaat tccaaaaatc gccgcctgag
      661 tgaggatgat aagcagttaa ataaagagat gtcagcgata cgaattgaaa ttgaacattt
      721 taacgctaaa ttcaagacct tccaaatcat gtcagtccct tatcgtaacc gcagaaaacg
      781 tttcgagtta cgggcggaat taatttgtgc catcatcaat tatgaagtga
//
LOCUS       DAVAZT010000117          810 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVAZT010000117 DAVAZT010000000
VERSION     DAVAZT010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 810)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 810)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..810
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.117"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(144..731)
                     /locus_tag="VQT45_002107"
     CDS             complement(144..731)
                     /locus_tag="VQT45_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2360348.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHTGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLF"
     gene            complement(734..>810)
                     /locus_tag="VQT45_002108"
     CDS             complement(734..>810)
                     /locus_tag="VQT45_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET2360349.1"
                     /translation="MPQSPWVERIVQVLDLDYEDLFRR"
BASE COUNT          298 a          167 c          111 g          234 t
ORIGIN      
        1 tctctccacc agtaaaatgc aagcaattat acaatgttgt cacatagaaa ataatgtttc
       61 cgtaactttt caaagtaact tccatctctc tcccaaaact ggaagttagt tttagaagtt
      121 acctaaaaat caggtcacct attttaaaaa agcagcaaac tataaactag taggttccac
      181 accaaatgta gtcccatact gccccataag tcagatttat agcgcaccat acctaaaaac
      241 atcccaagtg aaacatacaa acaccaagct agaatggttc ctgtatgatg tgctaaggca
      301 aataaaacac ttgtcaaagc aactctgata tctaattttc tgaccaaatt ccataaaatt
      361 tctcgataca gaaattcttc aaccatactc gcattgatta agaacaataa aaatgaaaac
      421 caaggaattt gatgttgaag gccaattaag tttgcttgat tcgtgcttcc ttgagcatga
      481 atcagactaa aacatagact tataatcagt aggctaacaa attcaacacc aagccatttc
      541 atcctagatt tcatattgac cttatgcgct tgtttgcgtt ggccatacat ccataaaaaa
      601 gaaatgagtg acgaaccata gagaatctgt agtatagtta actcaccgat acaaagaaat
      661 ttcaataagt atagagatac caataggaca tttacttgtt ggaatatata aactggaatt
      721 attcttttca tagttacctc cgaaataaat cttcataatc taaatctaat acctgcacaa
      781 tcctttctac ccatggactt tgaggcattc
//
LOCUS       DAVAZT010000118          774 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVAZT010000118 DAVAZT010000000
VERSION     DAVAZT010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 774)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 774)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..774
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.118"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            1..774
                     /locus_tag="VQT45_002109"
                     /pseudo
     CDS             1..774
                     /locus_tag="VQT45_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          237 a          158 c          137 g          242 t
ORIGIN      
        1 ccaattgaag aaatatgact ttcaaaaacc ttctaaaatt ccttatcttg aaacgactgg
       61 tatgcctact agaattctcc ttagaaagcg tcgtttcaag tgctatcact gttcaaaaat
      121 gatggtcgct gaaacttcta tcgtcaagaa taatcaccaa atccctcgta tcatcaacca
      181 aaagattgct caaaagttaa ttgaaaagat ttctatgact gatattgccc atcagctttc
      241 catctcaact tcaactgtta ttcgtaagct caatgacttc cactttgagt gtaattttag
      301 aaatctgcct gagattatgt cttgggacgt tgaaacagtc cggggagtga ctgtttcaat
      361 cgggagatgg agatgagctt cattgcgcaa gattttaaca atctcaatat catcactgtt
      421 cttgagggta gaacacaagc tgtcatccga gatcactttc ttaaatatga tagagccgtc
      481 cgatgtcgcg tcaaaattat tactatggat atgtttagtc cttactatga cttagctaga
      541 caacttttcc catgtgctaa aatcgtgttg gatcgctttc acattgtaca acatcttagc
      601 cgtgctatga gtcgtgtgcg tgttcaaatc atgaatcaat tggatcgaaa gtctcatgaa
      661 tacaaggcta tcaagcgcta ctggaagctc atacaacagg atagtcgtaa actcagcgat
      721 aaacattttt atcgccctac ttttcgtatg catttaacca ataaagagat ttta
//
LOCUS       DAVAZT010000119          671 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVAZT010000119 DAVAZT010000000
VERSION     DAVAZT010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 671)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 671)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..671
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.119"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..>671
                     /locus_tag="VQT45_002110"
     CDS             <1..>671
                     /locus_tag="VQT45_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2360350.1"
                     /translation="HVESDGLVFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKR
                     IARIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPSNPIDEKLVKEAV
                     RKVGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDRE
                     FYNKTYDLLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLVDDILAFLAPIR
                     HPERLG"
BASE COUNT          210 a          148 c          137 g          176 t
ORIGIN      
        1 catgtagaat ctgatggcct tgttttcgac ccagcgcaaa tcacaagtcg aaccgccaga
       61 ggtgtagctg tccctcatgg taaccattac cactttatcc cttatgaaca aatgtctgaa
      121 ttggaaaaac gaattgctcg tattattccc cttcgttatc gttcaaacca ttgggtacca
      181 gattcaagac cagaacaacc aagtccacaa tcgactccgg aacctagtcc aagtctgcaa
      241 cctgcaccaa atcctcaacc agctccaagc aatccaattg atgagaaatt ggtcaaagaa
      301 gctgttcgaa aagtaggcga tggttatgtc tttgaggaga atggagtttc tcgttatatc
      361 ccagccaagg atctttcagc agaaacagca gcaggcattg atagcaaact ggccaagcag
      421 gaaagtttat cgcataagct aggagctaag aaaactgacc tcccatctag tgatagagaa
      481 ttttacaata agacttatga cttactagca agaattcacc aagatttact tgataataaa
      541 ggtcgacaag ttgattttga ggctttggat aacctgttgg aacgactcaa ggatgtctca
      601 agtgataaag tcaagttagt ggatgatatt cttgccttct tagctccgat tcgtcatcca
      661 gaacgtttag g
//
LOCUS       DAVAZT010000120          662 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVAZT010000120 DAVAZT010000000
VERSION     DAVAZT010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..662
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.120"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            298..662
                     /locus_tag="VQT45_002111"
                     /pseudo
     CDS             298..662
                     /locus_tag="VQT45_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          200 a          115 c          125 g          222 t
ORIGIN      
        1 gttagttgtt tacttgcttc ataattcata gaactattat accatatttt gtttcgcagg
       61 aagtctattg aaaaatctcc agactagaga actcacggat agttcctaat ctggagattt
      121 cttatttgca cttttcttgt gcaactttag tccacggtaa ataggcctct aaaacctctt
      181 tgtttacgag agtttcctcg tttggaagac attctagaag ataggataga tatttctcgc
      241 tatttatact agactaaaat caaaaagcat tatacaatag tgatatgaaa tcaactgaag
      301 aaaagaaagc gctttaaaac cagtagacgt tttcataagg ttcgcttgat gtaccaagat
      361 gaggctggct tcggtagaat cagtaaactg ggatcttgtt ggtctccaat aggagtaggt
      421 ccacatgtcc atagtcacta tatacgagaa tttcactatt gttatggagc tgttgatgcc
      481 catacaggcg aatcattttt cttaatagct ggtggatgta atactgagtg gatgaacgcc
      541 tttttagaag agctttcaca agcttatcca gatgattatc ttttactcgt tatggacaat
      601 gctatatggc ataaatcaag taccttaaag actccgacta atattggttt tgcatttatt
      661 cc
//
LOCUS       DAVAZT010000121          650 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVAZT010000121 DAVAZT010000000
VERSION     DAVAZT010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..650
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.121"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            101..265
                     /locus_tag="VQT45_002112"
     CDS             101..265
                     /locus_tag="VQT45_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360351.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIAYVIAVMIYF
                     AINKKKGEKK"
     gene            262..>650
                     /locus_tag="VQT45_002113"
     CDS             262..>650
                     /locus_tag="VQT45_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET2360352.1"
                     /translation="MKTFFAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSVVFQF
                     LLVVINLASILVTVYLTREMRIREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITA
                     GESYQQIIAYIGAVLCLIIMLLLMWGL"
BASE COUNT          184 a          103 c          119 g          244 t
ORIGIN      
        1 atttatgatt tgagtgatcc aaggtcaaaa taagtgctat actagcagtg taaatgttct
       61 tgctcaacta agataaatcg cacatttagg aggaaatctt atgaagaaaa aaatactgat
      121 tattttcgtt ctgtatctaa tcatgtccat ctttctatat ccgcttaggg agagtgcttg
      181 gtatcagcta ttttatacca tagcctatgt gattgcagtt atgatctatt ttgctatcaa
      241 taaaaagaaa ggagaaaaga aatgaaaact ttttttgcta aaaaacggaa catcttcctt
      301 gcgagattgt tcttaggtca gttgcccttg cttgtttcta cttatctatt tctatctcgt
      361 cagtttttaa atttttccgt agttttccaa tttcttttag tagttattaa cttggcttct
      421 attttggtta ctgtttatct cactagggaa atgaggataa gagagtttga agatgatgat
      481 ttggttagtc ctagaaccaa tcaacttatg ttcatcggct tgacaggttt tatgtctatt
      541 atttgtttgt atagaggtat cacagcagga gaatcctacc aacaaataat cgcttatatt
      601 ggcgctgttc tctgcttaat catcatgctt ctgctcatgt ggggcttgaa
//
LOCUS       DAVAZT010000122          611 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVAZT010000122 DAVAZT010000000
VERSION     DAVAZT010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..611
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.122"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(189..>611)
                     /locus_tag="VQT45_002114"
     CDS             complement(189..>611)
                     /locus_tag="VQT45_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET2360353.1"
                     /translation="KPNEEKPQTEKPEEDKEHDEVSEPTHPESDEKENHAGLNPSADN
                     LYKPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNAVET
                     LTGLKSSLLLGTKDNNTISAEVDSLLALLKESQPTPIQ"
BASE COUNT          155 a          121 c           93 g          242 t
ORIGIN      
        1 gatgaagttt tttctcaact tcttttactt tattaaatag ttttctaaac cggttattta
       61 accatttaat taaccagtaa atagtttact atttaaaatt acttttgtca agtttctgtt
      121 acgtttttct aaaaaagaga agtaacacga aaggttactt ctccataaaa tatgctccat
      181 tcattttact actgtatagg agtcggttga ctttctttta acaaagccaa gagactatct
      241 acttctgctg aaatagtgtt attatctttc gttccgagaa gaagactact ttttagacca
      301 gtcaatgtct ccacagcatt ttgtctaata ctagaatctg ttactttttc tagcaaggcc
      361 tccgcctctg ctatcttagc gttaataaca gaatgctcta cttgaggaat ttcagcctca
      421 tctgtagtat cttcagcttc ttcctctgtc tcttccgtat cagtgcttgg tttataaaga
      481 ttatctgctg aaggatttaa accagcgtga ttctcttttt catcagattc agggtgagtt
      541 ggctcactta cttcatcatg ttccttatct tcctcaggtt tttctgtctg aggtttctcc
      601 tcgtttggtt t
//
LOCUS       DAVAZT010000123          569 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVAZT010000123 DAVAZT010000000
VERSION     DAVAZT010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..569
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.123"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..>569)
                     /locus_tag="VQT45_002115"
     CDS             complement(<1..>569)
                     /locus_tag="VQT45_002115"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360354.1"
                     /translation="AEALVDAEADALVEADSEAEVLAEADALVDAEADALVLAEADAL
                     VDAEADALVLAEAEALVDAEADALVLAEAEALVDAEADALVLAEADALVLAEAEALVD
                     AEAEALVDADSEALVDAEADALIDADSEADVLAEAEALVDAEAEALVDADSEALVDAE
                     AEADVDAEADALVDAEADALVDAEAEALV"
BASE COUNT          137 a          187 c          130 g          115 t
ORIGIN      
        1 tcaaccagcg cctcagcttc agcatcaacg agtgcgtcgg cttcagcatc aacgagtgca
       61 tcggcttcag catcaacgtc tgcctcagct tcagcgtcaa ccagtgcctc tgaatcggca
      121 tcaaccagtg cttcagcctc agcatcgaca agcgcttcgg cttcagcaag tacatcagct
      181 tctgaatctg catcaataag tgcgtcggct tcagcgtcaa ccagtgcctc tgaatcggca
      241 tcaaccagtg cttcagcctc agcatcaacg agtgcttcgg cttcagcaag tacaagtgcg
      301 tcagcttcag caagcacaag tgcgtcagct tcagcatcaa cgagcgcctc ggcttcagca
      361 agcaccagtg cgtcagcttc agcatcaacg agtgcctcgg cctcagcaag tacaagtgcg
      421 tcagcctcag catcaaccag tgcatcagcc tcagcaagta ccagtgcatc agcttccgca
      481 tcaacgagtg catcagcctc agcaagcacc tcagcttctg aatcggcctc aacgagtgcg
      541 tcagcctcag cgtcaacgag tgcttcggc
//
LOCUS       DAVAZT010000124          525 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVAZT010000124 DAVAZT010000000
VERSION     DAVAZT010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..525
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.124"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(238..325)
                     /locus_tag="VQT45_002116"
     tRNA            complement(238..325)
                     /locus_tag="VQT45_002116"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(289..291),aa:Ser,seq:gct)
     gene            complement(332..405)
                     /locus_tag="VQT45_002117"
     tRNA            complement(332..405)
                     /locus_tag="VQT45_002117"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(369..371),aa:Ile,seq:gat)
     gene            complement(440..510)
                     /locus_tag="VQT45_002118"
     tRNA            complement(440..510)
                     /locus_tag="VQT45_002118"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(476..478),aa:Gly,seq:tcc)
BASE COUNT          177 a          121 c           92 g          135 t
ORIGIN      
        1 gcaatgcctt tggttttcga aactttgaaa actttaaaaa acggattttt atcgctttga
       61 acatcaaaaa agaaaggacg aaatttgtcc tttctcgagc ttagcttttc ttcaacccac
      121 tacagttgac aaagagccat aaaaataact tcagattagt aattcaatta agttttacgg
      181 atctgaagct ttattgtctc taaaaataaa aaagagagtt acaaactctc attaaaacgg
      241 agaataaggg attcgaaccc ttgcgccagt tacccgacct aacgatttag caaaccgtcc
      301 tcttcagcct cttgagtaat tctccaatta atgggcacga gtggactcga accaccgacc
      361 tcacgcttat caggcgtgcg ctctaaccac ctgagctacg cgcccaagtc aaaaacttgg
      421 tacaaagaac aaagttcaaa gcgggtgacg agaatcgaac tcgcgacaac agcttggaag
      481 gctgtagttt taccactaaa ctacacccgc ataaatacta tcaat
//
LOCUS       DAVAZT010000125          509 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVAZT010000125 DAVAZT010000000
VERSION     DAVAZT010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..509
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.125"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..>509)
                     /locus_tag="VQT45_002119"
     CDS             complement(<1..>509)
                     /locus_tag="VQT45_002119"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360355.1"
                     /translation="AEALVEADSDALVEADSDAEVLAEAEALVDAEAEALVLAEADAL
                     VLAEAEALVDADSDAEVLAEAEALVLAEADALVDAEAEALVDAEAEALVDADSEADVL
                     AEADALVDADSDALVDAEAEALVDADAEALVLAEADALVLAEAEALVDAEAEALVLAE
                     ADALVEAEA"
BASE COUNT          123 a          168 c          116 g          102 t
ORIGIN      
        1 tcagcttcgg cctcaacaag tgcgtcagct tcagcaagca ccagtgcttc ggcttcagcg
       61 tcgacaagtg cctcagcttc agcaagtacc agtgcgtcag cctcagcaag tactagcgcc
      121 tcagcatcag cgtcaacaag tgcttcggct tcagcgtcaa cgagtgcgtc tgagtcagca
      181 tcaacgagtg cgtcagcctc agcaagcaca tcagcttctg aatccgcatc aacaagtgct
      241 tcagcctcag cgtcaacaag tgcttcagct tcagcatcaa ccagtgcatc agcttcagca
      301 agtactagcg cctcagcttc agcaagcacc tcagcgtctg aatcggcatc aacgagcgcc
      361 tcagcttcag caagtaccag tgcgtcagcc tcagcaagta ccagtgcttc agcctcagcg
      421 tcgacaagtg cctcggcttc agcaagtacc tcagcgtctg aatcggcctc aaccagtgca
      481 tctgaatcgg cctcaaccag tgcctcagc
//
LOCUS       DAVAZT010000126          482 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.126, whole genome shotgun sequence.
ACCESSION   DAVAZT010000126 DAVAZT010000000
VERSION     DAVAZT010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.126"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..>482)
                     /locus_tag="VQT45_002120"
     CDS             complement(<1..>482)
                     /locus_tag="VQT45_002120"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2360356.1"
                     /translation="EALVLAEADALVLAETEALVLAEAEALVDAEAEALVLAEAEALV
                     DADSDAEVLAEAEALVDAEAEALVLAEAEALVLADSDALVDAEAEALVDAEAEALVDA
                     EADALVDAEAEALVDAEAEALVDAEAEALVLAEADALVDAEAEALVLAEADALVEAEA
                     "
BASE COUNT          120 a          161 c          106 g           95 t
ORIGIN      
        1 tcagcttcgg cctcaacaag tgcgtcagct tcagcaagca ccagtgcttc ggcttcagcg
       61 tcgacaagtg cgtcagcctc agcaagcacc agtgcctcag cttcagcatc aacaagtgct
      121 tcagcctcag cgtcaacaag tgcttcagct tcagcatcaa caagtgcgtc agcttcagca
      181 tcaaccagtg cctcagcctc agcgtcgaca agtgcctcgg cttcagcatc gacaagtgca
      241 tctgaatcag caagcacaag tgcttcagct tcagcaagta ccagcgcctc agcctcagca
      301 tcaaccagtg cttcggcttc agcaagtacc tcagcgtctg aatcggcatc aacaagtgct
      361 tcagcttcag caagtacaag cgcctcagct tcagcatcaa ccagtgcttc ggcttcagca
      421 agcaccagtg cctcagtctc agcaagcacc agtgcgtcgg cttcagcaag cacaagcgcc
      481 tc
//
LOCUS       DAVAZT010000127          476 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.127, whole genome shotgun sequence.
ACCESSION   DAVAZT010000127 DAVAZT010000000
VERSION     DAVAZT010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.127"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..>476
                     /locus_tag="VQT45_002121"
     CDS             <1..>476
                     /locus_tag="VQT45_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2360357.1"
                     /translation="EQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEELLMKDPNY
                     QLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHSQHREGGTS
                     TNDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNELSASE"
BASE COUNT          158 a           89 c          106 g          123 t
ORIGIN      
        1 gaacaaatcg tcatcaagat aacagaccaa ggctatgtca cttcacatgg ggaccactat
       61 cattattaca atggtaaggt tccttatgac gctatcatca gtgaagaatt gctgatgaag
      121 gatccaaact accagctaaa ggacgaggat attatcagtg aaatcaaggg tggttatgtg
      181 attaaggtag atggaaaata ctatgtttac cttaaggatg cagctcatgc ggataatgtc
      241 cgtacaaaag aagaaatcaa tcggcaaaaa caagaacata gtcagcatcg tgaaggaggg
      301 acttcaacaa acgatggtgc ggtagccttt gcacgttcac aaggacgcta tactacagat
      361 gatggttata tctttaatgc ttctgatatc attgaggaca cgggtgatgc ttatatcgtt
      421 cctcacggcg accattacca ttacattcct aagaatgagt tatcagctag cgagtt
//
LOCUS       DAVAZT010000128          453 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.128, whole genome shotgun sequence.
ACCESSION   DAVAZT010000128 DAVAZT010000000
VERSION     DAVAZT010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..453
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.128"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            57..>453
                     /locus_tag="VQT45_002122"
     CDS             57..>453
                     /locus_tag="VQT45_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HET2360358.1"
                     /translation="MNDEASKQLTDARFKRLVSVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLHYVREYRTYEQIAADFGIHESNLIRRSQWVEVTLVQSGFTISR
                     TPLSSEDTVMIDATEVQINRPKKRISELFW"
BASE COUNT          152 a           85 c           90 g          126 t
ORIGIN      
        1 tccagtattt gacaatatta gacttcctgc gaaacaaaac atggtatagt agttctatga
       61 atgatgaagc aagtaaacaa ctaaccgatg cacgatttaa gcgtcttgtt agtgttcagc
      121 gtaccacttt tgaagagatg ttagctgtat taaaaacagc ttatcaactt aaacacgcaa
      181 aaggtggacg aaaacctaaa ttaagcctag aagaccttct tatggccact cttcactatg
      241 tgcgagaata tcgaacttat gaacaaattg cggctgattt tggtatccac gaaagcaact
      301 taatccgtcg gagccaatgg gttgaagtaa ctcttgttca aagtggtttt acgatttcaa
      361 gaactcctct cagttctgag gacacggtaa tgattgatgc gacggaagta caaatcaatc
      421 gccctaaaaa aagaattagc gaattattct ggt
//
LOCUS       DAVAZT010000129          433 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.129, whole genome shotgun sequence.
ACCESSION   DAVAZT010000129 DAVAZT010000000
VERSION     DAVAZT010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.129"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(46..432)
                     /locus_tag="VQT45_002123"
     CDS             complement(46..432)
                     /locus_tag="VQT45_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002202361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2360359.1"
                     /translation="MPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEDWARMGLPI
                     IRKEISNWHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYWTFLS
                     GKAEKQGITLYHHVLIDLFISYFNPL"
BASE COUNT          135 a           79 c           92 g          127 t
ORIGIN      
        1 cgtttggaag acattctaga agataggata gatatttctc actatttata atggattgaa
       61 ataagatatg aacaaatcga ttaggacatg atggtaaagc gtaatccctt gtttctcagc
      121 tttcccagac aaaaaagtcc agtagtaagt cagctgacta tcactctcta gcaccctata
      181 agaagtttca tccgcatgaa gtaagggctg agtcaatagt ctctctcgca agaggttata
      241 aaggggctcc aaatagtatt gactcgtctt gatatgccaa ttagagattt ccttacgtat
      301 gattggtaaa cccatcctag cccaatcttc ttcttggcga taattgggta ccttcagatt
      361 aaacttctga tggatggtgt gagcgataat agaagctgag ccaaagttat gcgctaaagg
      421 ggctttagga ata
//
LOCUS       DAVAZT010000130          430 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.130, whole genome shotgun sequence.
ACCESSION   DAVAZT010000130 DAVAZT010000000
VERSION     DAVAZT010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.130"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            321..>430
                     /locus_tag="VQT45_002124"
     CDS             321..>430
                     /locus_tag="VQT45_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIBC"
                     /protein_id="HET2360360.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIV"
BASE COUNT          152 a           59 c           78 g          141 t
ORIGIN      
        1 ctaatctgga gatttttcaa tagacttcgt tattgggcgg ttacgatatg atcactgact
       61 tcgtcagtct tatctacaac ctcaaaactg tgttttgagc aacctgcggc tagcttccta
      121 gtttgctctt tgattttcat tgagtattag aacagaaaaa atacttggag tatttgtttg
      181 tgtgtttatt tttatataac aaactataaa caaaacaaaa atataaaaaa agagacaaaa
      241 aagaacagaa agcaattgac aacggtttca tatagtgtta tacttatggc ataaagttaa
      301 tggaaagaag ggaaaaactt atggtattag attatttctt tgacaaaaac cttgtgtttt
      361 gcttagaagc ggataatcaa gaacaactct ttgatcaggt tgcaacttta ttggaagaac
      421 gagaaattgt
//
LOCUS       DAVAZT010000131          393 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.131, whole genome shotgun sequence.
ACCESSION   DAVAZT010000131 DAVAZT010000000
VERSION     DAVAZT010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..393
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.131"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..>393
                     /locus_tag="VQT45_002125"
     CDS             <1..>393
                     /locus_tag="VQT45_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET2360361.1"
                     /translation="YLHLWELSDWDQEGMLCLHELISREEGLVDDIPRLRKYFKTKFR
                     NRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQSK
                     EKQEELERVLSNERFRGRQRVLRDLRIVF"
BASE COUNT          143 a           57 c           93 g          100 t
ORIGIN      
        1 taccttcatt tatgggaatt gtcggattgg gaccaagaag gcatgctctg cttacatgaa
       61 ttgattagta gagaagaagg actggtagac gatattccac gtttaaggaa atatttcaaa
      121 accaagtttc gaaatcgaat tttagactat atccgtaagc aggaaagtca gaagcgtaga
      181 tacgataaag aaccctatga agaagtggga gagatcagtc atcgtataag tgaggggggt
      241 ctctggctag atgattatta tctctttcat gaaacactaa gagattatag aaacaaacaa
      301 agtaaagaga aacaagaaga actagaacgc gtcttaagca atgaacgatt tcgagggcgt
      361 caaagagtat taagagactt acgcattgtg ttt
//
LOCUS       DAVAZT010000132          310 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.132, whole genome shotgun sequence.
ACCESSION   DAVAZT010000132 DAVAZT010000000
VERSION     DAVAZT010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..310
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.132"
                     /strain="ST1"
                     /db_xref="taxon:1313"
BASE COUNT           87 a           38 c           74 g          111 t
ORIGIN      
        1 cgttgcggta actggagtgc ttttagttgg gaaaattgtt aattcattta aattgtaaac
       61 tttagggatt ctctgaagtt atggatgtcg ttccaatatg tgtacgttgg aatgttagtg
      121 cttatatggg gggaacagaa tcctctcttg attgaagaca agttagccat taggctggtt
      181 tgtctctttg tcaactgtag tgggttgata taatagtatt agtgagtggg ataaaagttt
      241 catttagttt attcagtaca aatttaacgg gtcaagattt attgaactgc accccaatag
      301 ttagacagaa
//
LOCUS       DAVAZT010000133          292 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.133, whole genome shotgun sequence.
ACCESSION   DAVAZT010000133 DAVAZT010000000
VERSION     DAVAZT010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.133"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            51..>292
                     /locus_tag="VQT45_002126"
     rRNA            51..>292
                     /locus_tag="VQT45_002126"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT           90 a           54 c           81 g           67 t
ORIGIN      
        1 gaaaaaaaca ataaatctgt cagtgacaga aatgagtgag aactcaaact tttaatgaga
       61 gtttgatcct ggctcaggac gaacgctggc ggcgtgccta atacatgcaa gtagaacgct
      121 gaaggaggag cttgcttctc tggatgagtt gcgaacgggt gagtaacgcg taggtaacct
      181 gcctggtagc gggggataac tattggaaac gatagctaat accgcataag agtagatgtt
      241 gcatgacatt tgcttaaaag gtgcacttgc atcactacca gatggacctg cg
//
LOCUS       DAVAZT010000134          288 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.134, whole genome shotgun sequence.
ACCESSION   DAVAZT010000134 DAVAZT010000000
VERSION     DAVAZT010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.134"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..>288
                     /locus_tag="VQT45_002127"
     CDS             <1..>288
                     /locus_tag="VQT45_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET2360362.1"
                     /translation="NRVKAAKKVPLDRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEW
                     FDEGLYEAPKGYTLEDLLATVKYYVEHPNERPHSDNGFGNASDHVQRNKNG"
BASE COUNT           93 a           59 c           59 g           77 t
ORIGIN      
        1 caaccgcgtg aaagcagcta agaaggtgcc acttgatcgt atgccttaca atcttcaata
       61 tactgtagaa gtcaaaaacg gtagtttaat catacctcat tatgaccatt accataacat
      121 caaatttgag tggtttgacg aaggccttta tgaggcacct aaggggtata ctcttgagga
      181 tcttttggcg actgtcaagt actatgtcga acatccaaac gaacgtccgc attcagataa
      241 tggttttggt aacgctagcg accatgttca aagaaacaaa aatggtca
//
LOCUS       DAVAZT010000135          277 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.135, whole genome shotgun sequence.
ACCESSION   DAVAZT010000135 DAVAZT010000000
VERSION     DAVAZT010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..277
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.135"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..>277
                     /locus_tag="VQT45_002128"
     CDS             <1..>277
                     /locus_tag="VQT45_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2360363.1"
                     /translation="QRIIEAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAM
                     QGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQG"
BASE COUNT          126 a           37 c           47 g           67 t
ORIGIN      
        1 aacaacgcat aatagaagca atcgaatcag ctttagaaaa agtagatgaa tatgctgaaa
       61 gttataatag actagaacag ctagataaag aatttccaga taaactaaaa aaatctattc
      121 ttcaatatgc tatgcaagga aaattagttg aacaagaccc aaatgatgaa tcagtcgaag
      181 ttttacttga aaaaatacga gcagaaaaac aaaaactctt tgaagaaggc aagattaaaa
      241 agaaagattt ggacatttct attgtttccc aaggaga
//
LOCUS       DAVAZT010000136          263 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.136, whole genome shotgun sequence.
ACCESSION   DAVAZT010000136 DAVAZT010000000
VERSION     DAVAZT010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..263
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.136"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(1..263)
                     /locus_tag="VQT45_002129"
                     /pseudo
     CDS             complement(1..263)
                     /locus_tag="VQT45_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="internal stop; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT           82 a           42 c           55 g           84 t
ORIGIN      
        1 tgaaaaagca agagctgata gagttgatag tggtgtttca agtcttccga ataactcaaa
       61 agcttgttta aaatctcttt attggttcaa tgcatacgaa aagtaggacg ataaaaatgt
      121 ttatcactca gtttacgact atcctgttga atgagtttcc agtagcgctt gatagccttg
      181 tattcatggg attttcgatg aaactgattt atgatttgaa cacgcacacg actcatagca
      241 cggctaagat gttgtacaat gtg
//
LOCUS       DAVAZT010000137          239 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.137, whole genome shotgun sequence.
ACCESSION   DAVAZT010000137 DAVAZT010000000
VERSION     DAVAZT010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..239
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.137"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(163..236)
                     /locus_tag="VQT45_002130"
     tRNA            complement(163..236)
                     /locus_tag="VQT45_002130"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(200..202),aa:Asn,seq:gtt)
BASE COUNT           86 a           47 c           34 g           72 t
ORIGIN      
        1 ctgttcgctc acaataagag agaacttttt tacgaaaatc tattgaatat gccataaaaa
       61 gattatacca cattgtgtac tatttttggt tcattttact ataacacgaa atagattatt
      121 attacataac aaaaaagagg tctaaacctc ttaactaaat tactccgcca gtaggactcg
      181 aacctacgac atcatgatta acagtcatgc gctactacca actgagctat ggcggatta
//
LOCUS       DAVAZT010000138          229 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.138, whole genome shotgun sequence.
ACCESSION   DAVAZT010000138 DAVAZT010000000
VERSION     DAVAZT010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..229
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.138"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..>229
                     /locus_tag="VQT45_002131"
     CDS             <1..>229
                     /locus_tag="VQT45_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2360364.1"
                     /translation="YTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHS
                     HWIKKDSLSEAERAAAQAYAKEKGLTPPSTDH"
BASE COUNT           72 a           49 c           55 g           53 t
ORIGIN      
        1 tacactgatg atgagattca agtagccaag ttggcaggca agtacacaac agaagacggt
       61 tatatctttg atcctcgtga tataaccagt gatgaggggg atgcctatgt aactccacat
      121 atgacccata gccactggat taaaaaagat agtttgtctg aagctgagag agcggcagcc
      181 caggcttatg ctaaagagaa aggtttgacc cctccttcga cagaccatc
//
LOCUS       DAVAZT010000139          204 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064491-rid20179543.denovo.139, whole genome shotgun sequence.
ACCESSION   DAVAZT010000139 DAVAZT010000000
VERSION     DAVAZT010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064491
            Sequence Read Archive: ERR351824
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980448.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980448.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:10:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,132
            CDSs (total)                      :: 2,093
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 67 of 142
            Pseudo Genes (incomplete)         :: 72 of 142
            Pseudo Genes (internal stop)      :: 36 of 142
            Pseudo Genes (multiple problems)  :: 29 of 142
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..204
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064491-rid20179543.denovo.139"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            79..152
                     /locus_tag="VQT45_002132"
     tRNA            79..152
                     /locus_tag="VQT45_002132"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:113..115,aa:Met,seq:cat)
BASE COUNT           47 a           48 c           59 g           50 t
ORIGIN      
        1 gggaacggtc ttgaaaaccg tcaggcgtgt aaaagcgtgc gtgggttcga atcccacatc
       61 ctccttttat attattaacg cgggatggag cagctcggta gctcgtcggg ctcataaccc
      121 gaaggtcgta ggttcaaatc ctgctcccgc aataaggctc ggtagctcag ttggtagagc
      181 aatggattga agctccatgt gtcg
//
